Serina Therapeutics
Serina Therapeutics, Inc. is a clinical-stage pharmaceutical company based in Huntsville, Alabama, focused on developing novel therapeutics for neurological diseases, cancer, pain, and metabolic disorders. Founded in 2006, the company utilizes its proprietary polymer technology, specifically polyoxazoline (POZ), to create new drug candidates. This technology allows for the attachment of small molecules, proteins, peptides, and DNA to the polymers, resulting in enhanced pharmacokinetic profiles that can improve safety and efficacy compared to the parent compounds. Serina's pipeline includes drug candidates aimed at treating conditions such as Parkinson’s disease, refractory epilepsy, post-operative pain, and chemotherapy-induced nausea and vomiting. The company's innovative POZ platform is designed to provide precise control over drug loading and release rates, addressing the limitations of traditional biocompatible polymers.
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AgeX Therapeutics
Acquisition in 2024
AgeX Therapeutics, Inc. is a biotechnology company based in Alameda, California, specializing in the development and commercialization of innovative therapeutics aimed at addressing human aging and degenerative diseases. The company harnesses proprietary technologies, including telomerase-mediated cell immortality and induced Tissue Regeneration, to create novel treatments. Its product pipeline features two primary cell-based candidates: AGEX-BAT1, which targets age-related metabolic disorders such as Type II diabetes, and AGEX-VASC1, designed to restore vascular support in ischemic tissues. Additionally, AgeX is working on AGEX-iTR1547, a drug formulation intended to enhance regenerative potential in aged tissues suffering from degenerative conditions. The company also offers human embryonic stem cells and a suite of genomic interpretation tools for researchers. AgeX has collaborated with the University of California, Irvine, on neural stem cell research related to Huntington's disease and other neurological disorders. Founded in 2017, AgeX continues to advance its mission of addressing the challenges associated with aging.
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