HealthPlan Data Solutions
Venture Round in 2025
Founded in 2010 by pharmacists, business executives, and software professionals, HealthPlan Data Solutions specializes in pharmacy benefits cost containment. Its platform analyzes prescription claims in real-time, reconciles them with contracts, and provides data-driven insights to control drug spending and improve health outcomes.
REM Electronics
Grant in 2025
REM Electronics is a distributor and manufacturer of electronic parts and components.
Orthobrain
Venture Round in 2025
Orthobrain empowers general dentists to offer orthodontic services through its digital platform. Combining AI-driven learning systems, expert mentorship, and comprehensive clinical support, Orthobrain enhances practice capabilities and patient outcomes. Its SimplyClear aligner system, awarded Product of the Year in 2024 by Benco, offers effective smile correction.
GE Aerospace
Grant in 2025
GE Aerospace specializes in designing, manufacturing, and servicing jet engines and integrated systems for commercial, military, business, and general aviation aircraft. With a global installed base of nearly 70,000 engines, the company generates significant recurring revenue through long-term service agreements. GE Aerospace is committed to developing sustainable products that reduce CO2 emissions by 20% and improve fuel efficiency.
XII Medical
Series B in 2024
XII Medical is a medical device developer focused on addressing obstructive sleep apnea through innovative technology. The company specializes in creating a minimally invasive outpatient solution that utilizes an implantable neurostimulation device. This device functions by preventing the muscles in the throat from relaxing during sleep, thereby avoiding airway blockage. By enhancing oropharyngeal airflow, XII Medical aims to provide patients with a proactive approach to managing their sleep apnea, improving their overall quality of life.
Metallus is an American-based manufacturer of alloy steel, carbon steel, and micro-alloy steel products, including special bar quality steel and seamless mechanical tubes. The company provides value-added solutions such as precision steel components and offers machining and thermal treatment services. It operates raw material recycling programs that feed its melt operations, supporting an integrated production process. Metallus serves customers across sectors including oil and gas, automotive, industrial equipment, mining, construction, rail, aerospace and defense, heavy trucking, agriculture, and power generation, delivering metal products and tube solutions for demanding applications.
OnStation
Series A in 2024
OnStation develops an application for construction and roadway projects that delivers instant jobsite location, access to plans and design documents, and team communication tools. Its Station Finder automatically determines a user’s location on the jobsite and can be adapted to operate with statewide milepost networks, enabling quick reference on smaller projects where survey data and documents may be limited. The platform reduces worker downtime, minimizes errors, and lowers project management overhead by centralizing site data and coordinating field teams, designers, and other stakeholders, thereby increasing worksite efficiency and consistency across roadway projects.
Abre.io provides an administration and data management platform for K-12 schools, consolidating learning management, school and classroom management, data capture, analytics, and communications into a centralized system. The platform integrates with other software, supports single sign-on, and visualizes data to support decision-making and improve outcomes for students inside and outside the classroom. By removing data silos, it enables stakeholders to turn analysis into action and aligns data to support the whole child.
Cloverleaf.me
Series A in 2024
Cloverleaf LLC offers a visualization and scenario-planning platform designed to enhance team management and employee development. Founded in 2015 and based in Covington, Kentucky, the platform analyzes employee data to provide insights into team dynamics by cross-mapping personality traits, skills, and organizational culture. This enables users, including agile practitioners, project managers, and human resource professionals, to position team members effectively, improve communication, and identify suitable candidates to boost productivity. Additionally, Cloverleaf's automated coaching features deliver personalized nudges through commonly used tools like Google Workspace, Microsoft Outlook, and Slack, fostering collaboration and performance improvements within teams.
AssetWatch
Venture Round in 2024
AssetWatch specializes in proactive predictive maintenance solutions. It offers a rapidly deployable remote condition monitoring service featuring wireless sensors, communication hubs, advanced software, and expert analysis. The company combines predictive analytics with expert insights to provide actionable recommendations, helping global manufacturers minimize unplanned downtime and transition from reactive to proactive maintenance.
Avation Medical
Series C in 2024
Avation Medical, Inc. is a company focused on developing a non-invasive closed-loop neuromodulation system aimed at treating overactive bladder in a home setting. Incorporated in 2016 and based in Columbus, Ohio, Avation Medical is at the forefront of innovation in wearable nerve stimulation systems. The company emphasizes empowering patients to manage their therapies, facilitating a more personalized approach to care. By leveraging advanced technologies, Avation Medical seeks to transform the neuromodulation market, enhancing the quality of care for individuals with chronic conditions through patient-centric solutions.
AlensiaXR
Series A in 2024
AlensiaXR is a technology startup, spun out of Case Western Reserve University, that specializes in developing a cutting-edge learning platform for human anatomy education. The company's innovative platform employs advanced mixed-reality technology to project and illuminate the human body in three dimensions, facilitating faster learning, improved information retention, and enhanced classroom engagement. This innovative approach also helps universities reduce the need for expensive and time-consuming cadaver procurement and maintenance.
Clarametyx Biosciences
Series A in 2024
Clarametyx Biosciences, Inc. is a biotechnology company founded in 2020 and headquartered in Columbus, Ohio. The company focuses on developing targeted and immune-enabling biologic therapies that address persistent infections associated with biofilms, which are protective layers that shield bacteria and complicate treatment. Clarametyx has created a novel technology platform that allows for the targeting of these biofilms, thereby enhancing immune response and facilitating antibiotic intervention. One of its key products in development is CMTX-001, a humanized monoclonal antibody currently in the late preclinical stage, aimed at treating hospital-acquired pneumonia. Clarametyx Biosciences is dedicated to combating life-threatening infections and reducing antibiotic resistance through its innovative therapeutic solutions.
Society Brands
Grant in 2023
Society Brands is a consumer products company established in 2020. Headquartered in Canton, Ohio, it acquires e-commerce native brands that primarily sell on Amazon and their own direct-to-consumer sites. The company aims to enhance the shopping experience for everyday products by integrating various brand offerings, focusing on e-commerce efficiency and customer engagement.
Lentechs
Venture Round in 2023
Lentechs is a medical device company based in Columbus, Ohio, specializing in the development of innovative soft bifocal contact lenses. The company focuses on creating a new generation of soft, suspended progressive contact lenses that enhance user experience by allowing natural eye movement, similar to that achieved with traditional bifocal glasses. This design aims to provide improved comfort and visual clarity, enabling users to see freely without discomfort. Lentechs is dedicated to addressing the needs of patients throughout their lifecycle, ensuring that its products offer both functionality and ease of use.
Enspire DBS Therapy
Series B in 2023
Enspire DBS Therapy focuses on restoring motor function for stroke survivors through proprietary deep brain stimulation (DBS) therapy combined with physical rehabilitation. It aims to accelerate post-stroke recovery by mediating the effects of stimulation and rehabilitation.
Invirsa develops therapeutic agents that enhance immunity and promote healing. Its lead compound, INV-102, reduces cellular injury caused by infections like adenovirus, stimulates immune response, and accelerates wound repair. Invirsa focuses on treating conditions such as keratoconjunctivitis and upper respiratory tract infections.
MediView
Venture Round in 2023
MediView, LLC is a medical device company based in Cleveland, Ohio, that specializes in developing augmented reality surgical navigation systems aimed at enhancing surgical processes for healthcare providers. Founded in 2017, the company focuses on creating advanced technologies for surgical navigation, particularly for the ablation and biopsy of cancerous tumors. MediView's flagship product, MediView, utilizes real-time, fused-holographic visualization to enable surgeons to navigate procedures with greater accuracy and efficacy. This innovative approach allows for enhanced examination of patients through augmented reality 3D visualization, facilitating improved surgical outcomes and supporting remote collaboration among healthcare professionals.
BIOHM is a microbiome-focused company specializing in digestive health. It offers a range of whole probiotics and gut microbiome testing services. Founded on over two decades of research by Dr. Ghannoum, supported by the National Institutes of Health (NIH), BIOHM's innovative approach addresses the critical role of fungi in maintaining digestive health.
Genetesis
Series C in 2022
Genetesis LLC, established in 2013 and based in Mason, Ohio, specializes in designing, developing, and providing biomagnetic imaging solutions for cardiac healthcare. The company's primary product is Genetesis CardioFlux, a mapping system that optimizes the detection, characterization, and treatment of cardiac rhythm disorders by visualizing electrical currents of the heart in 3D. Additionally, they offer Faraday Analytical Cloud, a HIPAA-compliant platform managing end-to-end data workflow for their Magnetocardiograph (MCG). Genetesis aims to redefine clinical diagnosis, monitoring, and screening processes for patients at risk of myocardial ischemia and coronary artery disease, using non-invasive, radiation-free methods.
Guided By Mushrooms
Grant in 2022
Guided By Mushrooms is an urban mushroom farm specializing in gourmet mushrooms, mycology products, mycological landscaping, and more.
Drive My Way
Venture Round in 2022
Drive My Way operates an online, personalized recruitment platform that connects CDL truck drivers with trucking companies and owner-operators. The service uses proprietary Matching technology to pair drivers with jobs based on qualifications and lifestyle preferences, including home time, benefits, location, and schedule. For employers, it provides a streamlined recruitment process by facilitating job postings, scoring candidates with a Match My Way metric, and exporting driver profiles into applicant tracking systems. Drivers can create profiles tailored to their qualifications and lifestyle, while a content portal offers industry news and networking opportunities. Founded in 2014 and headquartered in Chagrin Falls, Ohio, the company aims to improve hiring efficiency, reduce recruiting costs, and decrease turnover by delivering precise, data-driven job matches.
Founded in 2018, CIONIC develops precision bionics designed to enhance human performance and improve quality of life. The company specializes in wearable solutions that provide comprehensive analysis and precise augmentation, pushing the limits of integrated hardware, software, and algorithms.
OvationCXM
Series C in 2022
OvationCXM is a prominent provider of customer experience management solutions, specializing in the integration of artificial intelligence to enhance customer journeys. The company offers a comprehensive platform that empowers enterprises to identify and address friction points in real time across digital platforms, back-office operations, and partner interactions. This innovative platform features journey orchestration, knowledge management, generative AI, dynamic chat capabilities, and partner connectivity, all designed to deliver actionable, data-driven insights. By enabling businesses to achieve complete visibility and control over their customer experiences, OvationCXM supports revenue security, profitable growth, and the cultivation of customer loyalty and employee retention.
Centerline Biomedical
Series B in 2022
Centerline Biomedical, Inc. is a Cleveland, Ohio-based company founded in 2014 that specializes in developing advanced surgical navigation technologies. The company focuses on an Intra-Operative Positioning System, which utilizes non-x-ray based three-dimensional GPS technology to enhance the precision of endovascular procedures and minimize radiation exposure for both patients and medical staff. Centerline's innovative system aids surgeons in navigating complex three-dimensional vascular anatomy, thereby improving surgical outcomes in interventional vascular procedures. The technology is rooted in advancements made at the Cleveland Clinic, reflecting a commitment to enhancing the safety and effectiveness of minimally invasive surgeries.
AssetWatch
Series A in 2022
AssetWatch specializes in proactive predictive maintenance solutions. It offers a rapidly deployable remote condition monitoring service featuring wireless sensors, communication hubs, advanced software, and expert analysis. The company combines predictive analytics with expert insights to provide actionable recommendations, helping global manufacturers minimize unplanned downtime and transition from reactive to proactive maintenance.
SHARE Mobility
Series A in 2022
SHARE Mobility offers a comprehensive transportation management platform designed to optimize fleet operations and commuter transit services. The platform features real-time vehicle tracking, dynamic routing, customizable rider parameters, scheduling management, compliance reporting, and automated notifications, enabling efficient operations and tailored transit experiences for fleet operators, transit agencies, and organizations managing employee transportation.
Cloverleaf.me
Series A in 2022
Cloverleaf LLC offers a visualization and scenario-planning platform designed to enhance team management and employee development. Founded in 2015 and based in Covington, Kentucky, the platform analyzes employee data to provide insights into team dynamics by cross-mapping personality traits, skills, and organizational culture. This enables users, including agile practitioners, project managers, and human resource professionals, to position team members effectively, improve communication, and identify suitable candidates to boost productivity. Additionally, Cloverleaf's automated coaching features deliver personalized nudges through commonly used tools like Google Workspace, Microsoft Outlook, and Slack, fostering collaboration and performance improvements within teams.
XII Medical
Series A in 2022
XII Medical is a medical device developer focused on addressing obstructive sleep apnea through innovative technology. The company specializes in creating a minimally invasive outpatient solution that utilizes an implantable neurostimulation device. This device functions by preventing the muscles in the throat from relaxing during sleep, thereby avoiding airway blockage. By enhancing oropharyngeal airflow, XII Medical aims to provide patients with a proactive approach to managing their sleep apnea, improving their overall quality of life.
Orthobrain
Series A in 2022
Orthobrain empowers general dentists to offer orthodontic services through its digital platform. Combining AI-driven learning systems, expert mentorship, and comprehensive clinical support, Orthobrain enhances practice capabilities and patient outcomes. Its SimplyClear aligner system, awarded Product of the Year in 2024 by Benco, offers effective smile correction.
Rhyme
Venture Round in 2022
PriorAuthNow, Inc. is a software company based in Columbus, Ohio, established in 2014. The company specializes in developing solutions that facilitate the submission, monitoring, and completion of insurance prior authorization requests for medical providers. Its flagship product, PriorAuthNow, integrates with electronic health record systems and connects directly with insurance carriers, streamlining the prior authorization process. By serving a diverse range of clients, including hospitals, surgery centers, drug manufacturers, and other healthcare organizations, PriorAuthNow aims to enhance patient care access and improve the overall healthcare experience. The company focuses on creating a seamless workflow that empowers medical providers and their staff, ultimately driving patient satisfaction and transforming healthcare delivery.
Prevedere
Venture Round in 2022
Prevedere is a predictive analytics company based in Columbus, Ohio, with an additional office in Sunnyvale, California. Founded in 2012, the company specializes in developing business performance forecasting software that helps leaders make informed decisions by providing real-time insights into future business performance. Prevedere's platform tracks and manages economic, environmental, and consumer behavior data to identify leading indicators for company revenues, profits, and individual products. The company offers a range of solutions, including predictive marketing analytics, financial forecasting intelligence, demand planning, and sales planning. Additionally, Prevedere provides industry outlook reports, Chinese consumer behavior data, and predictive insights, along with economic consulting, data science, and training services.
Valley Foods
Debt Financing in 2021
Valley Foods is a family-owned business specializing in food service solutions. They manufacture and distribute shelf-stable meal kits, frozen sandwich meal kits, and retort trays for military applications, disaster relief efforts, and institutional programs like school summer programs.
Aware is a cloud intelligence platform that leverages advancements in cognitive computing, artificial intelligence, and behavioral analytics to enhance enterprise value through social graph monitoring. The company provides governance, compliance, and monitoring solutions aimed at improving connectivity, collaboration, and security within organizations. Their platform addresses challenges faced by legal, compliance, information security, and IT departments, offering tools for archiving, monitoring, organizational insights, data loss prevention, eDiscovery, retention, and legal holds. By harnessing insights into human behavior and interactivity, Aware aims to improve employee engagement while minimizing the risk of unsafe behavior in the workplace.
Eikonoklastes Therapeutics
Series A in 2021
Eikonoklastes Therapeutics is a biopharmaceutical company based in Cincinnati, Ohio, founded in 2019. The company focuses on developing innovative immunotherapies for severe diseases with high unmet clinical needs. Their pipeline includes two primary assets: ET-101, a gene therapy engineered to overexpress Caveolin-1 for treating neurodegenerative diseases, and ET-201, a tissue factor therapy targeting solid tumor cells, tumor vasculature, and tumor stem cells to inhibit tumor growth and recurrence. Eikonoklastes aims to rapidly advance these therapies from preclinical stages to clinical proof-of-concept and approval through relatively small clinical trials.
DAtAnchor
Convertible Note in 2021
Traditional IT controls focus on locking down networks, devices, and people. All of this is done in the name of protecting data. But, once files are moved, shared, or stolen, the data is no longer protected. Even worse, these controls get in the way and frustrate business users to the point they intentionally work around them. Anchor inverts the equation by baking protection into the data, invisible to the business users (like antivirus), so that files are free to travel and security is out of the way. Simply put, wherever the data goes, it is protected.
Anchor is a SaaS platform, with an endpoint component, that bakes protection into your files with a unique transparent combination of encryption, continuous multi-factor access controls, and a digital chain of custody. And when you do share or collaborate, Anchor protection stays with your data, even when it leaves your organization. Anchor empowers you to maintain control of your files while collaborating on premise or in the cloud, including forensic logging and revoking access.
In under 90 minutes, Anchor is fully deployed and empowers your business users to securely work and collaborate without complicated security products or rules in the way. All without requiring you to change existing IT controls or how your users and applications work today.
DAtAnchor is a result of a multi-year research activity, developed at Ohio State University. The development team currently has 6 members, 4 of which are full-time. We have seed level funding for >1M and an advisory board with members at the senior vice president level in Fortune 500 companies.
S4 Medical
Series A in 2021
Founded in 2017, S4 Medical specializes in developing medical devices for cardiac procedures. Its flagship product is a device designed to protect the esophagus during catheter ablation treatments for atrial fibrillation.
Aware is a cloud intelligence platform that leverages advancements in cognitive computing, artificial intelligence, and behavioral analytics to enhance enterprise value through social graph monitoring. The company provides governance, compliance, and monitoring solutions aimed at improving connectivity, collaboration, and security within organizations. Their platform addresses challenges faced by legal, compliance, information security, and IT departments, offering tools for archiving, monitoring, organizational insights, data loss prevention, eDiscovery, retention, and legal holds. By harnessing insights into human behavior and interactivity, Aware aims to improve employee engagement while minimizing the risk of unsafe behavior in the workplace.
Abre.io provides an administration and data management platform for K-12 schools, consolidating learning management, school and classroom management, data capture, analytics, and communications into a centralized system. The platform integrates with other software, supports single sign-on, and visualizes data to support decision-making and improve outcomes for students inside and outside the classroom. By removing data silos, it enables stakeholders to turn analysis into action and aligns data to support the whole child.
Ohio Valley Bank
Grant in 2019
Ohio Valley Bank is a full-service financial institution that operates primarily in Southeastern Ohio and western West Virginia. As a financial holding company, it offers a comprehensive range of commercial and consumer banking services. Customers can open various types of accounts, including checking and savings, as well as access trust services. The bank provides a variety of loan options, including personal, vehicle, VA, construction, and real estate loans, along with student loans. Additionally, Ohio Valley Bank facilitates individual retirement accounts, safe deposit boxes, and wire transfers, ensuring a complete suite of banking products to meet the needs of its clientele.
Transportation Research Center
Grant in 2017
Transportation Research Center (TRC Inc.) specializes in research and development testing services. Brakes, crashworthiness, emissions, durability, fuel economy, handling, driver training classes, and performance testing is conducted at the independent automotive proving ground. Facilities include a 7.5 mile (12.1 km) test track, 50-acre (20 hectare) vehicle dynamics area, 9,000 ft. x 84 ft. (2723 x 25 m) skid pad, wet basalt and tile surfaces, emissions lab, dynamic handling courses, off-highway area, and crash test barrier and simulator sled.
Ahalogy is a digital marketing company that operates as the Passion to Purchase Platform, focusing on helping brands and agencies connect with consumers through their interests. The company provides a range of services, including category trend data, authentic influencer content, and social optimization technology, which enable clients to enhance user engagement and drive sales. As an official Pinterest Marketing Partner, Ahalogy collaborates with leading social networks to deliver effective marketing solutions. Headquartered in Cincinnati, Ohio, Ahalogy also has offices in New York, Chicago, Los Angeles, and San Francisco, positioning itself in key markets for brand marketing. Through its innovative platform, Ahalogy aims to provide proven return on investment for its clients by leveraging data-driven insights and creative content strategies.