JobsOhio is a private non-profit economic development agency based in Columbus, Ohio, established in 2011. Its primary mission is to drive job creation and stimulate capital investment across the state. The organization focuses on attracting, retaining, and expanding businesses in strategic industry sectors that leverage Ohio's strengths. With a team of industry experts, JobsOhio provides essential resources and support to meet the needs of growing businesses, ensuring they have the tools necessary for success. Through its efforts, JobsOhio plays a crucial role in enhancing the economic landscape of Ohio.
Avation Medical, Inc. is focused on developing a non-invasive closed-loop neuromodulation system designed for the at-home treatment of overactive bladder. Established in 2016 and based in Columbus, Ohio, the company is pioneering wearable nerve stimulation platforms that emphasize patient empowerment and personalized care. By re-imagining neuromodulation through innovative, proven technologies, Avation Medical aims to enhance the management of chronic conditions, offering solutions that prioritize the needs and experiences of patients.
Clarametyx Biosciences
Series A in 2024
Clarametyx Biosciences, Inc. is a biotechnology company based in Columbus, Ohio, focused on developing targeted and immune-enabling biologic therapies to address persistent infections linked to biofilms. Founded in 2020, the company utilizes a novel technology platform designed to penetrate the protective layers surrounding bacteria, facilitating immune responses and enhancing the effectiveness of antibiotic interventions. Among its key developments is CMTX-001, a humanized monoclonal antibody currently in preclinical stages aimed at treating hospital-acquired pneumonia. Clarametyx's innovative approach seeks to combat life-threatening infections while addressing the growing concerns of antibiotic resistance.
Society Brands
Grant in 2023
Society Brands is a tech-enabled consumer products company based in Canton, Ohio, that specializes in acquiring e-commerce native brands. Established in 2020, the company focuses on brands that primarily sell through Amazon and their own direct-to-consumer (DTC) websites. By leveraging technology, Society Brands aims to optimize the growth and performance of the brands in its portfolio, enhancing their market presence and operational efficiency.
Lentechs
Venture Round in 2023
Lentechs is a medical device company based in Columbus, Ohio, specializing in the development of innovative soft bifocal contact lenses. The company focuses on creating a new generation of soft, suspended progressive contact lenses that enhance visual clarity and comfort. These lenses are designed to allow natural eye movement, similar to the experience of wearing bifocal glasses, while minimizing irritation. Lentechs aims to provide a comprehensive range of products that address the needs of patients throughout their visual health journey.
Enspire DBS Therapy
Series B in 2023
Enspire DBS Therapy, Inc. is dedicated to developing a proprietary deep brain stimulation (DBS) therapy aimed at restoring motor function in stroke survivors with disabilities. Founded in 2010 and based in Cleveland, Ohio, the company is currently conducting a Phase I clinical trial to evaluate the effectiveness of its DBS therapy in stroke recovery. The therapy integrates deep brain stimulation with physical rehabilitation techniques, leveraging natural pathways to enhance the effects of both stimulation and therapy. This innovative approach aims to accelerate recovery for stroke patients, offering them improved access to rehabilitation and the potential for greater restoration of motor function.
Invirsa
Series B in 2023
Invirsa Inc. is a biotechnology company based in Columbus, Ohio, established in 2016. The firm focuses on developing therapeutic agents to enhance immunity and promote wound healing, with its lead compound, INV-102, at the forefront of its research. INV-102 is a naturally occurring small molecule that aims to strengthen the immune response, reduce cellular injury caused by adenovirus, and stimulate DNA repair. The compound is being explored primarily for applications in ophthalmology and pulmonary medicine, targeting conditions such as keratoconjunctivitis and upper respiratory tract infections. Invirsa's approach not only seeks to reduce inflammation and viral infections but also has the potential to serve as a first-line therapy for common infectious diseases, addressing the significant number of viral pulmonary infections and infectious conjunctivitis cases in the United States.
MediView
Venture Round in 2023
MediView, LLC is a medical device company based in Cleveland, Ohio, established in 2017. The company specializes in developing an augmented reality surgical navigation system designed to enhance the surgical process for healthcare providers. Its primary product, MediView, utilizes extended reality technology to offer real-time, fused-holographic visualization, which aids in the ablation and biopsy of cancerous tumors. This innovative approach allows surgeons to navigate procedures with greater accuracy and efficacy compared to conventional two-dimensional displays. Additionally, MediView's technology supports remote collaboration and telehealth, providing healthcare professionals with valuable insights and the ability to examine patients more effectively using three-dimensional holograms.
Genetesis
Series C in 2022
Genetesis LLC is a medical technology company based in Mason, Ohio, that specializes in biomagnetic imaging solutions to improve patient diagnosis and monitoring of cardiac conditions. Founded in 2013, the company has developed the Genetesis CardioFlux, a mapping system designed to enhance the detection and treatment of cardiac rhythm disorders by visualizing the heart's electrical currents in three dimensions. Additionally, Genetesis offers the Faraday Analytical Cloud, a HIPAA-compliant platform that manages the data workflow for the CardioFlux magnetocardiograph. The system is non-invasive and avoids exposing patients to radiation or requiring exercise, enabling clinicians to accurately measure the magnetic signals generated by the heart during its electrical activity.
Centerline Biomedical
Series B in 2022
Centerline Biomedical, Inc. is a Cleveland-based company founded in 2014, focused on developing advanced navigation systems for interventional vascular procedures. The company specializes in a non-x-ray based, three-dimensional GPS surgical navigation technology that enhances the precision and outcomes of endovascular procedures while significantly reducing radiation exposure for both patients and healthcare providers. This innovative system assists surgeons in accurately navigating catheters and guide wires through the complex three-dimensional anatomy of patients with vascular diseases, ultimately enabling safer and more effective image-guided surgeries. The technology is rooted in research and development from the Cleveland Clinic, highlighting its commitment to improving surgical practices in the medical field.
Prevedere
Venture Round in 2022
Prevedere, Inc. is a predictive analytics company that specializes in business performance forecasting software. Founded in 2012 and headquartered in Columbus, Ohio, with an additional office in Sunnyvale, California, Prevedere provides a range of services including industry outlook reports, consumer behavior data, and predictive insights. The company's platform helps businesses monitor economic, environmental, and consumer behavior data to identify leading indicators for revenue and profit, thereby aiding in informed decision-making. Prevedere's offerings include predictive marketing analytics, financial forecasting intelligence, and demand planning solutions. The company also develops proprietary systems and APIs that integrate diverse data sources to ensure data accuracy and relevance. With a team comprising industry experts, data scientists, and economists, Prevedere supports organizations in navigating an ever-evolving market landscape.
Eikonoklastes Therapeutics
Series A in 2021
Eikonoklastes Therapeutics, Inc. is a biopharmaceutical company based in Cincinnati, Ohio, focused on developing innovative immunotherapies for diseases with significant unmet clinical needs. Since its incorporation in 2019, the company has established a pipeline of new therapies aimed at advancing from preclinical stages to clinical proof-of-concept efficiently and affordably. Its lead product, ET-101, is a gene therapy engineered to enhance the expression of Caveolin-1, which plays a critical role in neuromuscular signaling and aims to treat various neurodegenerative diseases. Additionally, Eikonoklastes is developing ET-201, a novel tissue factor therapy designed to target proteins prevalent in solid tumors, including triple-negative breast cancer and metastatic melanoma, while sparing normal cells. By addressing conditions such as ALS and cancers with high mortality, Eikonoklastes seeks to provide effective treatment solutions where current options are lacking. The company plans to expand its pipeline to include further indications with inadequate treatment alternatives, such as Alzheimer’s and Parkinson’s diseases.
DAtAnchor
Convertible Note in 2021
Traditional IT controls focus on locking down networks, devices, and people. All of this is done in the name of protecting data. But, once files are moved, shared, or stolen, the data is no longer protected. Even worse, these controls get in the way and frustrate business users to the point they intentionally work around them. Anchor inverts the equation by baking protection into the data, invisible to the business users (like antivirus), so that files are free to travel and security is out of the way. Simply put, wherever the data goes, it is protected. Anchor is a SaaS platform, with an endpoint component, that bakes protection into your files with a unique transparent combination of encryption, continuous multi-factor access controls, and a digital chain of custody. And when you do share or collaborate, Anchor protection stays with your data, even when it leaves your organization. Anchor empowers you to maintain control of your files while collaborating on premise or in the cloud, including forensic logging and revoking access. In under 90 minutes, Anchor is fully deployed and empowers your business users to securely work and collaborate without complicated security products or rules in the way. All without requiring you to change existing IT controls or how your users and applications work today. DAtAnchor is a result of a multi-year research activity, developed at Ohio State University. The development team currently has 6 members, 4 of which are full-time. We have seed level funding for >1M and an advisory board with members at the senior vice president level in Fortune 500 companies.
S4 Medical
Series A in 2021
S4 Medical, established in 2017 and headquartered in Cleveland, Ohio, specializes in manufacturing medical devices for catheter ablation treatment of atrial fibrillation. Its primary product, the eSolution device, is designed to minimize complications to the esophagus during these procedures.
Ohio Valley Bank
Grant in 2019
Ohio Valley Bank is a full-service financial institution headquartered in Southeastern Ohio, also serving western West Virginia. It offers a comprehensive range of banking services, including checking and savings accounts, trust services, and various types of loans such as personal, commercial, and real estate loans. The bank also provides specialized services like VA loans, vehicle loans, and student loans, as well as home loan options. In addition to traditional banking products, Ohio Valley Bank offers individual retirement accounts, safe deposit boxes, and wire transfers, ensuring a wide array of financial solutions for both individual and business clients.
Ahalogy
Series B in 2015
Ahalogy, now part of Quotient, operates as a digital marketing platform focused on connecting brands with consumers through their interests. It provides services that include category trend data, authentic influencer content, and social optimization technology. This enables brands and agencies to enhance user engagement and drive sales by leveraging proven return on investment strategies. Ahalogy is recognized as an official Pinterest Marketing Partner and collaborates with other major social networks to optimize marketing efforts. Headquartered in Cincinnati, Ohio, Ahalogy also maintains offices in New York, Chicago, Los Angeles, and San Francisco, positioning itself in key markets for brand marketing.
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