Incyte

Escient Pharmaceuticals, Inc. is a biotechnology company based in San Diego, California, specializing in the development and manufacture of G protein-coupled receptor (GPCR)-targeted drugs aimed at treating neuro-immuno-inflammatory and autoreactive diseases. Founded in 2017, Escient focuses on harnessing the therapeutic potential of specific orphan GPCRs, particularly the Mas-Related G-Protein Receptors (Mrgprs). The company aims to provide innovative therapies for a variety of conditions, including mast cell-mediated disorders and cholestatic pruritus, thereby expanding treatment options for healthcare providers facing these complex diseases.

BioTheryX is a clinical-stage biopharmaceutical company focused on restoring protein homeostasis through targeted protein degradation. It specializes in developing innovative small molecule degraders, initially targeting cancer, using its proprietary PRODEGY platform built upon expertise in Cereblon binding.

Villaris Therapeutics is a biopharmaceutical company developing novel antibody therapeutics for treating vitiligo and other tissue-specific autoimmune diseases involving pigmentation cells.

Agenus Inc. is a clinical-stage immuno-oncology company focused on the discovery, development, and commercialization of innovative immunotherapies and vaccines for cancer and infectious diseases. Based in Lexington, Massachusetts, the company aims to activate the immune system to recognize and combat cancer cells through a diverse portfolio that includes checkpoint antibodies, tumor microenvironment modifiers, and vaccine adjuvants. Agenus utilizes its proprietary Retrocyte Display platform for antibody discovery and develops a range of therapeutic candidates, including monoclonal antibodies and vaccines targeting various tumor-specific neo-epitopes. The company has several products in clinical trials, including CTLA-4 and PD-1 antagonists, and collaborates with notable partners such as Incyte Corporation and Merck Sharpe & Dohme to advance its immuno-oncology therapies. Founded in 1994, Agenus continues to build its capabilities in research, development, and manufacturing within the field of immunotherapy.

ARIAD Pharmaceuticals - European operations focuses on cancer.

Maxia Pharmaceuticals is a privately-held drug discovery and development company that specialized in small molecule drugs.

Iconix Biosciences specializes in toxicogenomics, offering a comprehensive database known as DrugMatrix, which includes microarray and pharmacology data. The company combines this extensive information with advanced informatics expertise to analyze and interpret toxicological data effectively. Additionally, Iconix has developed a library of Drug Signatures, which are genomic biomarkers that predict specific toxicological outcomes and mechanisms of action. This innovative approach aids pharmaceutical research by providing critical insights into the effects of various compounds, ultimately supporting the development of safer and more effective drugs.

De Novo Pharmaceuticals is an emerging computational drug design company. De Novo Pharmaceuticals uses its proprietary computational software for drug design to create novel, patentable lead molecules as candidates for drug development. De Novo's proprietary algorithms can convert information from structural genomics and medicinal chemistry rapidly into new chemical designs, maximising value within a pharmaceutical partner's research portfolio. De Novo's drug discovery partners include British Biotechnology, Aventis Pharmaceuticals and NV Organon.

Proteome is a privately held company specializing in proteomics information, focusing on the development of an integrated biological knowledge system that aids researchers in understanding gene and protein functions. The company's flagship product, the BioKnowledge Library, serves as a comprehensive database containing annotations for over 50,000 proteins across various organisms, including humans, rats, mice, worms, and yeast. This extensive library is curated by a network of nearly 100 scientists, ensuring high-quality and reliable data. Additionally, Proteome provides tools that transform scientific publications into analyzable relational data, facilitating sophisticated online searches for protein analysis and supporting the scientific community in their research endeavors.

GeneEd is the leading provider of e-Learning solutions for life science, combining advanced web technologies, creative design and educational skills into a productive and compelling learning experience. They take validated content created by domain experts and transform it into accredited multimedia courses including animations with synchronized streaming audio and thoughtfully designed interactive exercises. The courses are viewed in their Webinar™ environment that captures all of the positive attributes of a live seminar but retains the "anytime, any place, any pace" power of the internet. Their catalog courses are delivered using a platform that allows online registration, as well as student testing and tracking for corporate clients.

Synteni is a privately held microarray-based gene expression company. The company specializes in genetic research.