Parkinson's UK

Parkinson's UK is a charity dedicated to supporting individuals affected by Parkinson's disease and advancing research in the field. The organization focuses on providing crucial information, resources, and support to those living with the condition, as well as their families and caregivers. By funding innovative research initiatives, Parkinson's UK aims to improve treatment options and ultimately find a cure for the disease. Through various programs and community engagement, the charity works to raise awareness and foster understanding of Parkinson's, ensuring that those impacted have access to the support they need.

Arthur Roach Ph.D

Director of Research

7 past transactions

MISSION Therapeutics

Grant in 2024
MISSION Therapeutics is a biotechnology company specializing in developing drugs that target the cellular process of deubiquitylation for the treatment of cancer and other diseases. Their focus is on developing small molecule drugs that selectively inhibit specific deubiquitylating enzymes (DUBs), which play crucial roles in regulating protein degradation and cellular processes. These drugs aim to intervene in disease mechanisms where DUB dysregulation is implicated, offering potential therapeutic benefits.

Lucy Therapeutics

Venture Round in 2024
Lucy Therapeutics is a biotech company focused on developing innovative treatments for neurological diseases that originate from mitochondrial dysfunction. The company utilizes a unique approach to drug discovery by targeting early disease mechanisms, which holds potential for addressing a range of neurological disorders, including Parkinson's Disease and Alzheimer's Disease. In addition to its therapeutic efforts, Lucy Therapeutics is engaged in the development of proprietary small molecule therapies and diagnostic biomarkers aimed at enhancing the understanding and treatment of central nervous system conditions. By leveraging genetic technologies, the company aims to provide deeper insights into personalized medicine, thereby improving patient outcomes and enabling more precise healthcare interventions in the neurological field.

Neumora Therapeutics

Grant in 2024
Neumora Therapeutics operates as a clinical-stage biotechnology company pioneering precision medicines for brain diseases through the integration of data science and neuroscience.

University of Nottingham

Grant in 2024
The University of Nottingham is a leading, financially secure, campus-based institution renowned for its research, international outlook, and comprehensive academic offerings. It provides undergraduate sport courses and boasts a prestigious business school with campuses in the UK, China, and Malaysia, renowned for its influential research and strong corporate connections. The university is committed to internationalising its core activities, recruiting top students and staff globally, and preparing students for successful futures.

NRG Therapeutics

Seed Round in 2021
NRG Therapeutics is a drug discovery company established in 2018 that specializes in developing therapeutic approaches aimed at restoring mitochondrial function to address neurodegenerative diseases, including Parkinson’s disease, Alzheimer’s disease, and motor neuron disease. The company focuses on creating novel medicines that preserve mitochondrial function and halt disease progression. With a team experienced in neuroscience drug discovery, NRG Therapeutics is initially concentrating on the discovery and development of brain-penetrant inhibitors of the mitochondrial permeability transition pore specifically for Parkinson’s disease. This strategic focus is intended to empower physicians with effective treatment options for patients suffering from chronic neurodegenerative disorders.

NRG Therapeutics

Grant in 2019
NRG Therapeutics is a drug discovery company established in 2018 that specializes in developing therapeutic approaches aimed at restoring mitochondrial function to address neurodegenerative diseases, including Parkinson’s disease, Alzheimer’s disease, and motor neuron disease. The company focuses on creating novel medicines that preserve mitochondrial function and halt disease progression. With a team experienced in neuroscience drug discovery, NRG Therapeutics is initially concentrating on the discovery and development of brain-penetrant inhibitors of the mitochondrial permeability transition pore specifically for Parkinson’s disease. This strategic focus is intended to empower physicians with effective treatment options for patients suffering from chronic neurodegenerative disorders.

Keapstone Therapeutics

Seed Round in 2018
Keapstone Therapeutics Limited is a biotechnology company based in Sheffield, United Kingdom, focused on drug development targeting the Nrf2 signaling pathway for conditions such as Parkinson's disease and Motor Neuron Disease (MND). Founded in 2017, the company specializes in developing a novel series of small molecule activators that prevent the interaction between KEAP1 and Nrf2. This mechanism enhances redox balance, improves mitochondrial function, promotes autophagy, and reduces inflammation, ultimately aiming to improve the quality of life for individuals suffering from Parkinson's disease. In addition to its drug development efforts, Keapstone Therapeutics engages in biotechnology research and offers consulting services related to fatal neurodegenerative diseases.
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