Alloy Ventures is an early-stage venture capital firm based in Palo Alto, California, founded in 1996. The firm specializes in investing across various sectors, including life sciences, information technology, healthcare, software-as-a-service, manufacturing, mobile technology, media, telecommunications, and cleantech. Alloy Ventures focuses on identifying and supporting innovative companies at the forefront of these industries in the United States.
Agari is a security company focused on protecting businesses from phishing and social engineering attacks. It employs advanced data science and various signals to defend against threats such as business email compromise, supply chain fraud, spear phishing, and account takeovers. By addressing these vulnerabilities, Agari helps reduce business risk and restore trust in email communications. Additionally, the company safeguards outbound emails from enterprises to customers, enhancing email deliverability and maintaining brand integrity. Through its data-driven security platform, Agari aims to eliminate email as a viable channel for cyber-attacks, ensuring safer interactions for both businesses and consumers.
AEGEA Medical
Series D in 2018
AEGEA Medical, Inc. is a medical technology company based in Menlo Park, California, focused on improving women's healthcare through innovative treatment options. The company has developed a water vapor ablation system, known as Mara, which provides a safe and effective method for endometrial ablation to treat heavy menstrual bleeding, or menorrhagia. This FDA-approved technology allows for a straightforward, office-based procedure that typically takes only minutes to perform. AEGEA is dedicated to enhancing patient outcomes and expanding access to effective therapies, while also supporting physicians in delivering these procedures with confidence and ease. Founded in 2008, AEGEA Medical is committed to pioneering advancements in women’s health.
Agari
Series D in 2016
Agari is a security company focused on protecting businesses from phishing and social engineering attacks. It employs advanced data science and various signals to defend against threats such as business email compromise, supply chain fraud, spear phishing, and account takeovers. By addressing these vulnerabilities, Agari helps reduce business risk and restore trust in email communications. Additionally, the company safeguards outbound emails from enterprises to customers, enhancing email deliverability and maintaining brand integrity. Through its data-driven security platform, Agari aims to eliminate email as a viable channel for cyber-attacks, ensuring safer interactions for both businesses and consumers.
AEGEA Medical
Series C in 2015
AEGEA Medical, Inc. is a medical technology company based in Menlo Park, California, focused on improving women's healthcare through innovative treatment options. The company has developed a water vapor ablation system, known as Mara, which provides a safe and effective method for endometrial ablation to treat heavy menstrual bleeding, or menorrhagia. This FDA-approved technology allows for a straightforward, office-based procedure that typically takes only minutes to perform. AEGEA is dedicated to enhancing patient outcomes and expanding access to effective therapies, while also supporting physicians in delivering these procedures with confidence and ease. Founded in 2008, AEGEA Medical is committed to pioneering advancements in women’s health.
Restoration Robotics
Series C in 2014
Restoration Robotics is a privately held medical device company focused on advancing hair transplantation technology. It has developed the ARTAS™ System, an innovative image-guided platform that facilitates follicular unit extraction, enhancing the precision and efficiency of hair restoration procedures. By integrating advanced imaging and robotics, Restoration Robotics aims to improve outcomes for patients seeking hair transplants, positioning itself as a leader in the evolving field of hair restoration. The company is committed to transforming traditional practices through its state-of-the-art technology.
Agari
Series C in 2014
Agari is a security company focused on protecting businesses from phishing and social engineering attacks. It employs advanced data science and various signals to defend against threats such as business email compromise, supply chain fraud, spear phishing, and account takeovers. By addressing these vulnerabilities, Agari helps reduce business risk and restore trust in email communications. Additionally, the company safeguards outbound emails from enterprises to customers, enhancing email deliverability and maintaining brand integrity. Through its data-driven security platform, Agari aims to eliminate email as a viable channel for cyber-attacks, ensuring safer interactions for both businesses and consumers.
GigaOm
Series F in 2014
GigaOm is a media company that specializes in providing news, analysis, and opinions on startups and emerging technologies. Founded in 2006 by Om Malik and based in San Francisco, GigaOm aims to humanize technology and offer deep insights into disruptive companies and trends. The company attracts over 6.5 million unique monthly readers who rely on its content to comprehend significant technological disruptions and the business opportunities that arise from them. GigaOm's information is produced by a network of more than 200 independent analysts, who deliver timely content bridging breaking news and long-term research. Additionally, GigaOm hosts events that combine focused editorial content with opportunities for attendees to engage with technology disruptors, equipping them with the tools needed to capitalize on emerging trends. The company serves both individual and corporate subscribers, making it a valuable resource for those seeking in-depth analysis of the technology landscape.
Grand Junction
Venture Round in 2013
Grand Junction, Inc., based in San Francisco, California, operates a Software-as-a-Service platform that facilitates local deliveries across the United States and Canada. Acquired by Target Corporation in 2017, the company has managed nearly 100 million deliveries to date and is recognized as the sole provider of same-day delivery in every market within these regions. Grand Junction's technology platform supports a diverse range of clients, including small to medium-sized businesses, Fortune 500 companies, and individual consumers, by connecting them with a network of 700 local carriers. The platform offers various delivery options, including on-demand, same-day, scheduled, and two-person deliveries, providing users with tools such as dashboards, GPS alerts, and invoice auditing. This comprehensive approach enhances customer experience while significantly reducing delivery costs. By allowing clients to customize their service offerings, Grand Junction empowers businesses to optimize their local delivery processes.
Hightail
Series E in 2013
Hightail, Inc. is a cloud services company that specializes in file sharing and creative collaboration, enabling professionals to share large files such as videos, designs, artwork, and presentations. Founded in 2004 and based in Campbell, California, Hightail offers a platform that enhances visual project management by allowing users to preview files, comment, assign tasks, and manage versions visually. The company serves a diverse clientele, including agencies, creative and marketing departments, and businesses worldwide. Hightail also provides digital transformation services, focusing on data organization and content protection through various business processes. In 2013, Hightail rebranded from its original name, YouSendIt, and it operates as a subsidiary of Open Text Corporation.
Scifiniti
Series B in 2013
Scifiniti is an early-stage company focused on developing innovative technology for photovoltaic cells. The company aims to provide a low-cost, drop-in replacement for traditional crystalline silicon wafers by directly creating high-quality wafers with a suitable crystal structure for solar applications. This novel approach eliminates the need for the conventional processes of casting polysilicon ingots and sawing them into wafers, potentially enhancing performance and reducing production costs in the solar energy market. By streamlining the manufacturing process, Scifiniti's technology could significantly impact the solar industry, enabling businesses to produce and sell more efficient solar modules.
OptiMedica
Series E in 2013
OptiMedica Corporation, established in 2004 and based in Silicon Valley, is a global ophthalmic device company focused on enhancing patient outcomes through innovative technologies. The company is dedicated to transforming cataract surgery by developing a reproducible, noninvasive technique that utilizes femtosecond laser technology to replace traditional manual steps, which can be inconsistent. This approach aims to provide cataract surgeons with improved precision, control, performance, and efficacy. OptiMedica has conducted clinical trials for its Catalys Precision Laser System, yielding promising results. Although the system is not available for sale in the United States at this time, OptiMedica anticipates launching it in both U.S. and international markets.
RainDance Technologies
Series E in 2013
RainDance Technologies, based in Billerica, Massachusetts, specializes in developing genomic tools for non-invasive liquid biopsy applications focused on the research, early detection, and treatment of cancer, as well as other inherited and infectious diseases. The company offers a range of innovative products, including the RainDrop digital polymerase chain reaction platform, which utilizes picoliter-sized droplets for multiplex detection of various genetic materials. Additionally, RainDance provides the ThunderStorm automated next-generation sequencing content enrichment solution, and the ThunderBolts NGS panels, designed for profiling significant cancer mutations and targeting genes associated with myeloid disorders. Through its advanced droplet technology, RainDance enables research institutions and laboratories to conduct precise genetic analysis, facilitating the understanding of complex genetic variations. Founded in 2004, the company operates as a subsidiary of Bio-Rad Laboratories and serves a global market through sales representatives and distributors.
Labcyte
Series D in 2013
Labcyte Inc. is a laboratory instrumentation company based in San Jose, California, specializing in acoustic droplet ejection (ADE) technology for life sciences applications. Established in 2000, Labcyte develops innovative solutions for drug discovery, genomic research, cancer research, and personalized medicine through its precise liquid dispensing technology. This technology utilizes focused acoustic energy to eject nanoliter-scale droplets of fluid, allowing for high accuracy and reduced consumption of materials. Labcyte's product offerings include automation systems, laboratory workstations, and control software aimed at enhancing research efficiency and data reliability. The company operates as a subsidiary of Beckman Coulter, Inc. and maintains additional offices across multiple countries, including Canada, the United Kingdom, and Japan.
Genomatica
Series D in 2012
Genomatica, Inc. is a biotechnology company based in San Diego, California, specializing in the development of manufacturing processes for intermediate and basic chemicals derived from renewable feedstocks. Founded in 1998, the company utilizes its proprietary biotechnology platform to create fermentation-based processes and to engineer microorganisms that facilitate the conversion of these feedstocks into essential chemicals. Genomatica has successfully commercialized processes for chemicals such as butanediol, which is used in biodegradable plastics and apparel, and butylene glycol, commonly found in cosmetics and personal care products. The company is also actively working on bio-nylon and has developed a pipeline targeting the production of 20 different chemicals. Recognized for its innovative technologies, Genomatica has received numerous accolades, including the Kirkpatrick Award for outstanding chemical engineering technology and the ICIS Innovation Award for its Brontide butylene glycol.
Siluria Technologies
Series C in 2012
Siluria Technologies is a materials innovation company focused on addressing global challenges in the natural gas, chemicals, and fuel sectors. By leveraging advancements in nanotechnology, biotechnology, and chemical engineering, Siluria has created a platform that enables the efficient production of chemicals and fuels from natural gas, which is a more abundant and cost-effective resource than oil. The company's technology allows for the conversion of natural gas and low-value by-products into higher-value products, including liquid fuels such as gasoline, diesel, and jet fuel. Siluria's research and development teams are actively working towards commercializing their technology through partnerships with leading chemical and fuel companies, facilitating pilot-scale production to integrate their innovations into existing industry infrastructure.
Ensenda
Venture Round in 2012
Ensenda is a prominent third-party logistics provider specializing in local delivery services across North America. The company operates a comprehensive network of local carriers that facilitate home and commercial deliveries, catering to various industries, including furniture retail, industrial supply, printing, office supplies, electronics, and logistics. With a focus on enhancing the delivery experience, Ensenda addresses a critical segment of the supply chain often overlooked by businesses. The local delivery sector, valued at $46 billion, is vital for customer loyalty and sales, as it encompasses the final step in the transportation process. Ensenda's diverse range of delivery programs is available in every market throughout the United States and Canada, positioning the company as a leader in this essential industry.
Agari
Series A in 2011
Agari is a security company focused on protecting businesses from phishing and social engineering attacks. It employs advanced data science and various signals to defend against threats such as business email compromise, supply chain fraud, spear phishing, and account takeovers. By addressing these vulnerabilities, Agari helps reduce business risk and restore trust in email communications. Additionally, the company safeguards outbound emails from enterprises to customers, enhancing email deliverability and maintaining brand integrity. Through its data-driven security platform, Agari aims to eliminate email as a viable channel for cyber-attacks, ensuring safer interactions for both businesses and consumers.
Siluria Technologies
Series B in 2011
Siluria Technologies is a materials innovation company focused on addressing global challenges in the natural gas, chemicals, and fuel sectors. By leveraging advancements in nanotechnology, biotechnology, and chemical engineering, Siluria has created a platform that enables the efficient production of chemicals and fuels from natural gas, which is a more abundant and cost-effective resource than oil. The company's technology allows for the conversion of natural gas and low-value by-products into higher-value products, including liquid fuels such as gasoline, diesel, and jet fuel. Siluria's research and development teams are actively working towards commercializing their technology through partnerships with leading chemical and fuel companies, facilitating pilot-scale production to integrate their innovations into existing industry infrastructure.
Verinata Health
Series C in 2011
Verinata Health focuses on maternal and fetal health by developing non-invasive tests for the early identification of fetal chromosomal abnormalities. Utilizing proprietary technologies, the company analyzes cell-free DNA in maternal blood to offer a safe and accurate assessment of fetal aneuploidy. This approach aims to alleviate the anxiety associated with traditional prenatal screening methods that often involve multiple steps, high false-positive rates, and invasive procedures. Verinata seeks to provide women with a straightforward solution, consisting of a single blood draw that delivers definitive results. The company is also conducting a large-scale, prospective, blinded pivotal study to validate the sensitivity and specificity of its prenatal test, with results anticipated to enhance the understanding and effectiveness of prenatal care.
Restoration Robotics
Series C in 2011
Restoration Robotics is a privately held medical device company focused on advancing hair transplantation technology. It has developed the ARTAS™ System, an innovative image-guided platform that facilitates follicular unit extraction, enhancing the precision and efficiency of hair restoration procedures. By integrating advanced imaging and robotics, Restoration Robotics aims to improve outcomes for patients seeking hair transplants, positioning itself as a leader in the evolving field of hair restoration. The company is committed to transforming traditional practices through its state-of-the-art technology.
Crux Biomedical
Series C in 2011
Crux Biomedical, Inc., established in August 2004 by physicians Tom Fogarty and Frank Arko, focuses on developing innovative medical devices to address the limitations of existing vena cava filters. The company's primary product, the Crux VCF System, serves as a preventive device for pulmonary embolisms, effectively stopping blood clots from reaching the lungs. This system is particularly beneficial for patients at risk of pulmonary embolism who are unable to tolerate blood thinners, providing a vital method for preventing potentially life-threatening clots.
Infineta Systems
Series B in 2011
Infineta Systems is a privately-held network infrastructure company that develops and markets a line of high-performance network optimization products. Infineta’s system architecture will power a generation of products to address the urgent need for high-speed enterprise data center interconnects. Infineta is pioneering a new category of products that will help Global 2000 enterprises address the explosion in inter-data center traffic resulting from mission-critical storage replication, backup and emerging “private cloud†applications. At the center of this architecture is Infineta’s patent-pending Velocity Dedupe Engine™. The Velocity Dedupe Engine is providing an innovative, hardware-based solution to obtain the high throughput and zero-latency requirements necessary for today’s enterprise data centers. Infineta offers customers dramatically lower costs and more control of their critical data center-to-data center traffic. Customers leverage the Infineta solution to build high-performance inter-data center fabric, transforming a rigid and inflexible model into an agile ‘global area network’ of pooled resources for a more powerful and cost-effective computing experience.
Mavenir
Series E in 2011
Mavenir develops a cloud-native network software, a mobile communications software stack that runs on cloud infrastructure and connects devices, as well as people to the internet and apps, thereby offering multimedia messaging for connectivity among people.
AEGEA Medical
Series B in 2011
AEGEA Medical, Inc. is a medical technology company based in Menlo Park, California, focused on improving women's healthcare through innovative treatment options. The company has developed a water vapor ablation system, known as Mara, which provides a safe and effective method for endometrial ablation to treat heavy menstrual bleeding, or menorrhagia. This FDA-approved technology allows for a straightforward, office-based procedure that typically takes only minutes to perform. AEGEA is dedicated to enhancing patient outcomes and expanding access to effective therapies, while also supporting physicians in delivering these procedures with confidence and ease. Founded in 2008, AEGEA Medical is committed to pioneering advancements in women’s health.
GigaOm
Series E in 2011
GigaOm is a media company that specializes in providing news, analysis, and opinions on startups and emerging technologies. Founded in 2006 by Om Malik and based in San Francisco, GigaOm aims to humanize technology and offer deep insights into disruptive companies and trends. The company attracts over 6.5 million unique monthly readers who rely on its content to comprehend significant technological disruptions and the business opportunities that arise from them. GigaOm's information is produced by a network of more than 200 independent analysts, who deliver timely content bridging breaking news and long-term research. Additionally, GigaOm hosts events that combine focused editorial content with opportunities for attendees to engage with technology disruptors, equipping them with the tools needed to capitalize on emerging trends. The company serves both individual and corporate subscribers, making it a valuable resource for those seeking in-depth analysis of the technology landscape.
Cameron Health
Series F in 2011
Cameron Health, Inc. is a development-stage medical device company focused on creating advanced implantable electronic devices aimed at improving patient care in the field of cardiac health. The company specializes in the development and manufacturing of subcutaneous implantable defibrillator (S-ICD) systems designed for patients at risk of life-threatening ventricular tachyarrhythmias. Their product line includes the SQ-RX pulse generator, which is essential for managing cardiac arrhythmias, and the Q-TRAK subcutaneous electrode, designed for optimal placement within the body. Additionally, the Q-TECH programmer enables wireless communication with the SQ-RX device, enhancing device functionality. Cameron Health's mission is to address unmet medical needs through innovative technology, leveraging the expertise of its team to tackle complex medical challenges.
RainDance Technologies
Series D in 2011
RainDance Technologies, based in Billerica, Massachusetts, specializes in developing genomic tools for non-invasive liquid biopsy applications focused on the research, early detection, and treatment of cancer, as well as other inherited and infectious diseases. The company offers a range of innovative products, including the RainDrop digital polymerase chain reaction platform, which utilizes picoliter-sized droplets for multiplex detection of various genetic materials. Additionally, RainDance provides the ThunderStorm automated next-generation sequencing content enrichment solution, and the ThunderBolts NGS panels, designed for profiling significant cancer mutations and targeting genes associated with myeloid disorders. Through its advanced droplet technology, RainDance enables research institutions and laboratories to conduct precise genetic analysis, facilitating the understanding of complex genetic variations. Founded in 2004, the company operates as a subsidiary of Bio-Rad Laboratories and serves a global market through sales representatives and distributors.
GigaOm
Series D in 2010
GigaOm is a media company that specializes in providing news, analysis, and opinions on startups and emerging technologies. Founded in 2006 by Om Malik and based in San Francisco, GigaOm aims to humanize technology and offer deep insights into disruptive companies and trends. The company attracts over 6.5 million unique monthly readers who rely on its content to comprehend significant technological disruptions and the business opportunities that arise from them. GigaOm's information is produced by a network of more than 200 independent analysts, who deliver timely content bridging breaking news and long-term research. Additionally, GigaOm hosts events that combine focused editorial content with opportunities for attendees to engage with technology disruptors, equipping them with the tools needed to capitalize on emerging trends. The company serves both individual and corporate subscribers, making it a valuable resource for those seeking in-depth analysis of the technology landscape.
Siluria Technologies
Series A in 2010
Siluria Technologies is a materials innovation company focused on addressing global challenges in the natural gas, chemicals, and fuel sectors. By leveraging advancements in nanotechnology, biotechnology, and chemical engineering, Siluria has created a platform that enables the efficient production of chemicals and fuels from natural gas, which is a more abundant and cost-effective resource than oil. The company's technology allows for the conversion of natural gas and low-value by-products into higher-value products, including liquid fuels such as gasoline, diesel, and jet fuel. Siluria's research and development teams are actively working towards commercializing their technology through partnerships with leading chemical and fuel companies, facilitating pilot-scale production to integrate their innovations into existing industry infrastructure.
Ciranova
Venture Round in 2010
Ciranova, Inc. is an electronic design automation company based in Santa Clara, California, established in 2002. The company specializes in developing interoperable tools aimed at aiding custom chip designers in the creation and migration of legacy analog intellectual property (IP). Its product offerings include PyCell Studio, which streamlines the creation of parameterized cells (PCell) and layout generators for advanced manufacturing processes, and PCell Xtreme, designed to facilitate the migration of PCells from proprietary languages into multi-vendor OpenAccess environments. Additionally, Ciranova provides services such as custom layout generator development, Python code development consulting, and analog and mixed-signal design support, enabling engineers to integrate complex RF, analog, and mixed-signal content into nanometer-scale silicon efficiently.
Xactly
Series F in 2010
Xactly is a prominent global provider of cloud-based Sales Performance Management solutions designed to enhance the effectiveness of sales organizations. The company specializes in planning and managing sales quotas, territories, and incentive compensation, while also offering predictive analytics to inform strategic decision-making. Its software platform enables employers to design and automate compensation plans that align employee incentives with business objectives. By delivering error-free commission payments and on-demand visibility, Xactly fosters employee trust and loyalty, thereby improving operational efficiencies and productivity. The company's solutions aim to optimize sales behaviors, enhance employee performance, and mitigate risks, ultimately supporting organizations in achieving their business goals.
Hightail
Series D in 2010
Hightail, Inc. is a cloud services company that specializes in file sharing and creative collaboration, enabling professionals to share large files such as videos, designs, artwork, and presentations. Founded in 2004 and based in Campbell, California, Hightail offers a platform that enhances visual project management by allowing users to preview files, comment, assign tasks, and manage versions visually. The company serves a diverse clientele, including agencies, creative and marketing departments, and businesses worldwide. Hightail also provides digital transformation services, focusing on data organization and content protection through various business processes. In 2013, Hightail rebranded from its original name, YouSendIt, and it operates as a subsidiary of Open Text Corporation.
PacBio
Series F in 2010
PacBio designs, develops, and manufactures sequencing systems to resolve genetically complex problems. Its single molecule real-time (SMRT) sequencing technology enables single molecule real-time detection of biological processes.
BarRx Medical
Series D in 2010
BARRX Medical, Inc. specializes in developing endoscopic treatment solutions for Barrett's esophagus, a precancerous condition linked to gastroesophageal reflux disease (GERD). The company offers advanced ablation systems, including HALOFLEX, HALO360, and HALO90, which utilize a balloon-based electrode to deliver a uniform and controlled ablation effect aimed at removing diseased tissue and promoting the regrowth of healthy cells. Clinical studies have demonstrated the effectiveness of these systems, showing high rates of complete eradication of dysplasia and intestinal metaplasia, along with a significant reduction in disease progression and cancer development. The HALO systems have received FDA clearance for use in the United States and hold CE Mark approval for Europe. To date, more than 58,000 procedures have been successfully performed in over 400 hospitals globally. Founded in 2000 and based in Sunnyvale, California, BARRX Medical is a privately-held company committed to addressing chronic gastroenterological diseases.
Xactly
Series E in 2010
Xactly is a prominent global provider of cloud-based Sales Performance Management solutions designed to enhance the effectiveness of sales organizations. The company specializes in planning and managing sales quotas, territories, and incentive compensation, while also offering predictive analytics to inform strategic decision-making. Its software platform enables employers to design and automate compensation plans that align employee incentives with business objectives. By delivering error-free commission payments and on-demand visibility, Xactly fosters employee trust and loyalty, thereby improving operational efficiencies and productivity. The company's solutions aim to optimize sales behaviors, enhance employee performance, and mitigate risks, ultimately supporting organizations in achieving their business goals.
Mavenir
Series D in 2010
Mavenir develops a cloud-native network software, a mobile communications software stack that runs on cloud infrastructure and connects devices, as well as people to the internet and apps, thereby offering multimedia messaging for connectivity among people.
Apptera
Venture Round in 2010
Apptera is a mobile communications and advertising company that specializes in delivering multimedia content and interactive experiences to mobile devices. Its flagship product, Raved, enhances consumer engagement while the Apptera MobileAd Network connects advertisers with a diverse array of publishers, enabling effective outreach to millions of mobile users. The company collaborates with notable partners such as AOL Moviefone and Movietickets.com to maximize advertising impact. Founded in 2001 and based in Silicon Valley, Apptera has received several industry accolades, including recognition as one of the OnMobile 100 Top Private Companies in 2011. The company also holds multiple patents related to its communications technology, underscoring its innovative approach in the mobile advertising space. Apptera maintains additional offices in New York and Los Angeles, reflecting its expansive operational footprint.
Scifiniti
Series A in 2010
Scifiniti is an early-stage company focused on developing innovative technology for photovoltaic cells. The company aims to provide a low-cost, drop-in replacement for traditional crystalline silicon wafers by directly creating high-quality wafers with a suitable crystal structure for solar applications. This novel approach eliminates the need for the conventional processes of casting polysilicon ingots and sawing them into wafers, potentially enhancing performance and reducing production costs in the solar energy market. By streamlining the manufacturing process, Scifiniti's technology could significantly impact the solar industry, enabling businesses to produce and sell more efficient solar modules.
Infineta Systems
Series A in 2010
Infineta Systems is a privately-held network infrastructure company that develops and markets a line of high-performance network optimization products. Infineta’s system architecture will power a generation of products to address the urgent need for high-speed enterprise data center interconnects. Infineta is pioneering a new category of products that will help Global 2000 enterprises address the explosion in inter-data center traffic resulting from mission-critical storage replication, backup and emerging “private cloud†applications. At the center of this architecture is Infineta’s patent-pending Velocity Dedupe Engine™. The Velocity Dedupe Engine is providing an innovative, hardware-based solution to obtain the high throughput and zero-latency requirements necessary for today’s enterprise data centers. Infineta offers customers dramatically lower costs and more control of their critical data center-to-data center traffic. Customers leverage the Infineta solution to build high-performance inter-data center fabric, transforming a rigid and inflexible model into an agile ‘global area network’ of pooled resources for a more powerful and cost-effective computing experience.
Genomatica
Series C in 2010
Genomatica, Inc. is a biotechnology company based in San Diego, California, specializing in the development of manufacturing processes for intermediate and basic chemicals derived from renewable feedstocks. Founded in 1998, the company utilizes its proprietary biotechnology platform to create fermentation-based processes and to engineer microorganisms that facilitate the conversion of these feedstocks into essential chemicals. Genomatica has successfully commercialized processes for chemicals such as butanediol, which is used in biodegradable plastics and apparel, and butylene glycol, commonly found in cosmetics and personal care products. The company is also actively working on bio-nylon and has developed a pipeline targeting the production of 20 different chemicals. Recognized for its innovative technologies, Genomatica has received numerous accolades, including the Kirkpatrick Award for outstanding chemical engineering technology and the ICIS Innovation Award for its Brontide butylene glycol.
Integrating PV
Series A in 2010
Integrated Photovoltaics is a leading developer of next-generation photovoltaic solutions. Integrated Photovoltaics is a privately held company headquartered in Sunnyvale, California.
Standard BioTools
Venture Round in 2009
Standard BioTools, previously known as Fluidigm, is driven by a bold vision – unleashing tools to accelerate breakthroughs in human health. Standard BioTools has an established portfolio of essential, standardized next-generation technologies that help biomedical researchers develop medicines faster and better. As a leading solutions provider, the Company provides reliable and repeatable insights in health and disease using its proprietary mass cytometry and microfluidics technologies that help transform scientific discoveries into better patient outcomes. Standard BioTools works with leading academic, government, pharmaceutical, biotechnology, plant and animal research, and clinical laboratories worldwide, focusing on the most pressing needs in translational and clinical research, including oncology, immunology, and immunotherapy.
Cambrios Technologies
Series D in 2009
Cambrios Technologies Corporation specializes in developing and manufacturing advanced electronic materials, particularly electrodes made from silver nanowires. These materials simplify the manufacturing processes for electronic devices while enhancing their performance. The company's flagship product, ClearOhm, consists of silver nanowire coating materials that create transparent conducting layers on various substrates. This technology is applicable to a wide range of products, including touch screens, liquid crystal displays, e-paper, organic light-emitting diodes (OLED), and thin film photovoltaics. Founded in 2002 as Semzyme, Inc., the company rebranded to Cambrios Technologies Corporation in 2004 and is headquartered in Sunnyvale, California, with additional offices in Japan and Taiwan. Cambrios aims to leverage its nanostructured materials to improve the efficiency and capabilities of next-generation consumer devices.
Ravenflow
Venture Round in 2009
Ravenflow specializes in business requirements definition software that accelerates the application development process for enterprises. Its flagship product, RAVEN, facilitates requirements elicitation and definition, enabling stakeholders to reach consensus more quickly and reducing approval times for specifications. By minimizing developer rework caused by requirements errors, RAVEN integrates seamlessly with various application lifecycle management platforms, enhancing the overall efficiency of project delivery. The software helps business analysts visualize and validate requirements, produce specifications for business process workflows and use cases, and address specific application needs. Additionally, Ravenflow offers training and professional services to support its clients across multiple sectors, including finance, banking, insurance, government, telecommunications, technology, healthcare, education, and independent software vendors.
Teradici
Series C in 2009
Teradici Corporation specializes in PC-over-IP (PCoIP) technology, which facilitates the transmission of software images from central servers or workstations to various PCoIP-ready endpoints. This technology enhances the management and provisioning of computing services, supporting diverse work styles including local, remote, and mobile environments. Teradici offers a range of PCoIP solutions, including zero clients, optimized thin clients, hardware accelerators, remote workstation cards, and workstation access software, all designed to provide high-definition, secure computing experiences. The company's offerings also include cloud solutions such as desktop virtualization infrastructure and remote workstation services, along with optimization and monitoring tools. Teradici serves a wide array of clients, including Fortune 500 companies, educational institutions, government agencies, and cloud service providers, and collaborates with OEM partners globally. Founded in 2004 and headquartered in Burnaby, Canada, Teradici emphasizes innovation and has secured over 40 patents to date.
SynergEyes
Series C in 2009
SynergEyes, Inc. is a technology-driven company specializing in the manufacture and sale of contact lenses for eye care professionals. Founded in 2001 and based in Carlsbad, California, SynergEyes focuses on hybrid contact lenses that combine the clarity of rigid gas permeable lenses with the comfort of soft lenses. Their product offerings cater to various eye conditions, including astigmatism, presbyopia, myopia, hyperopia, and keratoconus. By utilizing advanced high-Dk materials and vision-optimized designs, SynergEyes aims to enhance vision and quality of life for its patients. The company's products are distributed in the United States and internationally, addressing a recognized need for innovative lens solutions in the eye care industry.
Crux Biomedical
Series B in 2009
Crux Biomedical, Inc., established in August 2004 by physicians Tom Fogarty and Frank Arko, focuses on developing innovative medical devices to address the limitations of existing vena cava filters. The company's primary product, the Crux VCF System, serves as a preventive device for pulmonary embolisms, effectively stopping blood clots from reaching the lungs. This system is particularly beneficial for patients at risk of pulmonary embolism who are unable to tolerate blood thinners, providing a vital method for preventing potentially life-threatening clots.
Humanigen
Series D in 2008
Humanigen, Inc. is a clinical-stage biopharmaceutical company based in Burlingame, California, that specializes in the development of proprietary monoclonal antibodies aimed at immunotherapy and oncology treatments. The company’s leading candidate, Lenzilumab, targets granulocyte-macrophage colony-stimulating factor and is currently undergoing Phase Ib/II clinical trials for chronic myelomonocytic leukemia and juvenile myelomonocytic leukemia. Additionally, Humanigen is developing Ifabotuzumab, which targets the EphA3 receptor and has completed the Phase I portion of a Phase I/II clinical trial for various hematologic malignancies. The company is also working on HGEN005, an anti-EMR1 monoclonal antibody in the pre-clinical stage for eosinophilic diseases. Humanigen has established collaborations, including a clinical partnership with Kite Pharma to study Lenzilumab in patients with relapsed or refractory diffuse large B-cell lymphoma and a research agreement with the Department of Defense to facilitate the development of Lenzilumab for potential emergency use in COVID-19. Formed in 2000, the company was previously known as KaloBios Pharmaceuticals and rebranded as Humanigen in 2017.
Mavenir
Series C in 2008
Mavenir develops a cloud-native network software, a mobile communications software stack that runs on cloud infrastructure and connects devices, as well as people to the internet and apps, thereby offering multimedia messaging for connectivity among people.
Apptera
Debt Financing in 2008
Apptera is a mobile communications and advertising company that specializes in delivering multimedia content and interactive experiences to mobile devices. Its flagship product, Raved, enhances consumer engagement while the Apptera MobileAd Network connects advertisers with a diverse array of publishers, enabling effective outreach to millions of mobile users. The company collaborates with notable partners such as AOL Moviefone and Movietickets.com to maximize advertising impact. Founded in 2001 and based in Silicon Valley, Apptera has received several industry accolades, including recognition as one of the OnMobile 100 Top Private Companies in 2011. The company also holds multiple patents related to its communications technology, underscoring its innovative approach in the mobile advertising space. Apptera maintains additional offices in New York and Los Angeles, reflecting its expansive operational footprint.
Apptera
Venture Round in 2008
Apptera is a mobile communications and advertising company that specializes in delivering multimedia content and interactive experiences to mobile devices. Its flagship product, Raved, enhances consumer engagement while the Apptera MobileAd Network connects advertisers with a diverse array of publishers, enabling effective outreach to millions of mobile users. The company collaborates with notable partners such as AOL Moviefone and Movietickets.com to maximize advertising impact. Founded in 2001 and based in Silicon Valley, Apptera has received several industry accolades, including recognition as one of the OnMobile 100 Top Private Companies in 2011. The company also holds multiple patents related to its communications technology, underscoring its innovative approach in the mobile advertising space. Apptera maintains additional offices in New York and Los Angeles, reflecting its expansive operational footprint.
Verinata Health
Series C in 2008
Verinata Health focuses on maternal and fetal health by developing non-invasive tests for the early identification of fetal chromosomal abnormalities. Utilizing proprietary technologies, the company analyzes cell-free DNA in maternal blood to offer a safe and accurate assessment of fetal aneuploidy. This approach aims to alleviate the anxiety associated with traditional prenatal screening methods that often involve multiple steps, high false-positive rates, and invasive procedures. Verinata seeks to provide women with a straightforward solution, consisting of a single blood draw that delivers definitive results. The company is also conducting a large-scale, prospective, blinded pivotal study to validate the sensitivity and specificity of its prenatal test, with results anticipated to enhance the understanding and effectiveness of prenatal care.
GigaOm
Series C in 2008
GigaOm is a media company that specializes in providing news, analysis, and opinions on startups and emerging technologies. Founded in 2006 by Om Malik and based in San Francisco, GigaOm aims to humanize technology and offer deep insights into disruptive companies and trends. The company attracts over 6.5 million unique monthly readers who rely on its content to comprehend significant technological disruptions and the business opportunities that arise from them. GigaOm's information is produced by a network of more than 200 independent analysts, who deliver timely content bridging breaking news and long-term research. Additionally, GigaOm hosts events that combine focused editorial content with opportunities for attendees to engage with technology disruptors, equipping them with the tools needed to capitalize on emerging trends. The company serves both individual and corporate subscribers, making it a valuable resource for those seeking in-depth analysis of the technology landscape.
ForteBio
Series C in 2008
ForteBio is a life science company focused on developing analytical systems for protein quantification and the characterization of protein-protein interactions. The company offers the Octet family of instruments, which facilitate real-time analysis of biomolecular interactions using micro-volume samples. These instruments provide essential data on affinity, kinetics, and concentration for proteins, peptides, DNA, RNA, and small molecules. Key products in the Octet line include the Octet RED, which is designed for quantitation and kinetics analysis while also enhancing the range and resolution for small molecule screening, as well as the Octet Q and QK models that perform similar analytical functions. By enabling rapid, real-time results, ForteBio's systems support scientists in their research endeavors.
Humanigen
Series D in 2008
Humanigen, Inc. is a clinical-stage biopharmaceutical company based in Burlingame, California, that specializes in the development of proprietary monoclonal antibodies aimed at immunotherapy and oncology treatments. The company’s leading candidate, Lenzilumab, targets granulocyte-macrophage colony-stimulating factor and is currently undergoing Phase Ib/II clinical trials for chronic myelomonocytic leukemia and juvenile myelomonocytic leukemia. Additionally, Humanigen is developing Ifabotuzumab, which targets the EphA3 receptor and has completed the Phase I portion of a Phase I/II clinical trial for various hematologic malignancies. The company is also working on HGEN005, an anti-EMR1 monoclonal antibody in the pre-clinical stage for eosinophilic diseases. Humanigen has established collaborations, including a clinical partnership with Kite Pharma to study Lenzilumab in patients with relapsed or refractory diffuse large B-cell lymphoma and a research agreement with the Department of Defense to facilitate the development of Lenzilumab for potential emergency use in COVID-19. Formed in 2000, the company was previously known as KaloBios Pharmaceuticals and rebranded as Humanigen in 2017.
Kalobios Pharmaceuticals
Series D in 2008
KaloBios Pharmaceuticals provides medicines for respiratory diseases and certain cancers. The company is a biopharmaceutical company focused on advancing medicines for patients with neglected and rare diseases. They designed to overcome marketed antibody products.
3Leaf
Series C in 2008
3Leaf Systems specializes in server virtualization solutions that enhance corporate data center initiatives, focusing on power management and optimized scale-out architectures. Their Virtual Compute Environment (VCE) architecture provides system-level virtualization, allowing organizations to achieve mainframe-class capabilities on commodity servers. By utilizing 3Leaf's technology, businesses can significantly lower their infrastructure and operational costs while enabling rapid deployment and provisioning of data center resources. This ensures that organizations can meet the demands of modern applications effectively.
Hightail
Series C in 2008
Hightail, Inc. is a cloud services company that specializes in file sharing and creative collaboration, enabling professionals to share large files such as videos, designs, artwork, and presentations. Founded in 2004 and based in Campbell, California, Hightail offers a platform that enhances visual project management by allowing users to preview files, comment, assign tasks, and manage versions visually. The company serves a diverse clientele, including agencies, creative and marketing departments, and businesses worldwide. Hightail also provides digital transformation services, focusing on data organization and content protection through various business processes. In 2013, Hightail rebranded from its original name, YouSendIt, and it operates as a subsidiary of Open Text Corporation.
PacBio
Series E in 2008
PacBio designs, develops, and manufactures sequencing systems to resolve genetically complex problems. Its single molecule real-time (SMRT) sequencing technology enables single molecule real-time detection of biological processes.
Verinata Health
Series C in 2008
Verinata Health focuses on maternal and fetal health by developing non-invasive tests for the early identification of fetal chromosomal abnormalities. Utilizing proprietary technologies, the company analyzes cell-free DNA in maternal blood to offer a safe and accurate assessment of fetal aneuploidy. This approach aims to alleviate the anxiety associated with traditional prenatal screening methods that often involve multiple steps, high false-positive rates, and invasive procedures. Verinata seeks to provide women with a straightforward solution, consisting of a single blood draw that delivers definitive results. The company is also conducting a large-scale, prospective, blinded pivotal study to validate the sensitivity and specificity of its prenatal test, with results anticipated to enhance the understanding and effectiveness of prenatal care.
Moxsie
Series A in 2008
Moxsie is an online retailer where shoppers can discover independent fashion - including clothing, footwear and accessories from new, up and coming designers.
Zannel
Series B in 2008
Zannel makes the mobile industry's first Instant Media Network(TM), which allows people to instantly and visually communicate what's happening now across mobile and the web, including all major social networks. Zannel won a Webby for Best Mobile Social Network in 2008, serves million of unique visitors per month, has over 50 partnerships with leading operators, media companies, and brands. Founded by the team that built the first large-scale mobile media storefronts in the US, Zannel combines the best of mobile messaging, media sharing, and social networking into an intuitive, compelling user experience. Located in San Francisco, Zannel is backed by USVP, Alloy, and Palomar Ventures.
Molecular Imprints
Venture Round in 2008
Molecular Imprints Inc., founded in 2001 and based in Austin, Texas, specializes in manufacturing imprint and lithography systems designed for creating nanometer-scale surface relief structures. The company is recognized for its Jet and Flash imprint lithography technology, which offers advanced nanopatterning capabilities for various high-tech industries, including displays, life sciences, and light-emitting diodes. With a robust intellectual property portfolio, Molecular Imprints has applied for over 700 patents, resulting in more than 100 issued patents that encompass imprint tools, materials, and process technology. The core of its technology, the Jet and Flash Imprint Lithography, employs the IntelliJet Drop Pattern Generator to achieve precise placement of photoresist on substrates in extremely small volumes, facilitating the uniform imprinting of features down to 10 nanometers and below. Through a combination of specialized competencies and strategic partnerships, Molecular Imprints delivers innovative solutions that meet the demanding needs of its customers.
NovaSys
Venture Round in 2008
NovaSys Health is a prominent provider of managed healthcare services, operating one of the largest health plans in Arkansas. With approximately 11,000 contracted providers in the region and over 4,300 in Arkansas, the company emphasizes strong relationships with healthcare providers. It offers a range of health plans and related services, including customized solutions, provider relations, and eligibility and billing administration, catering to a diverse network of hospitals, physicians, and ancillary providers.
NOVASYS MEDICAL
Series D in 2008
$25 million in Series C preferred stock financing. The financing will be used to ramp up operations and prepare for sales and marketing in anticipation of the company commercializing its first product, the Novasys Micro-remodeling™ System. The system, which is designed to treat female stress urinary incontinence (SUI), has received the CE Mark for use in the European Union and is pending FDA marketing clearance for sale in the United States. Novasys Medical Inc is testing a new, non-incisional, transurethral treatment which requires no visualization of the treatment site (neither cystoscopy nor fluoroscopy), being guided by familiar balloon palpation (similar to a Foley catheter). In addition, the Novasys Micro-remodeling™ System incorporates numerous, automatic safety features making the treatment process very easy to learn and use. The treatment does not require general anesthesia and is performed in the outpatient or office setting. Not only is the treatment rapid (less than 10 minutes), but patients immediately return to virtually all activities. As there are no incisions, no wound care or dressing changes are required.
Xactly
Series D in 2008
Xactly is a prominent global provider of cloud-based Sales Performance Management solutions designed to enhance the effectiveness of sales organizations. The company specializes in planning and managing sales quotas, territories, and incentive compensation, while also offering predictive analytics to inform strategic decision-making. Its software platform enables employers to design and automate compensation plans that align employee incentives with business objectives. By delivering error-free commission payments and on-demand visibility, Xactly fosters employee trust and loyalty, thereby improving operational efficiencies and productivity. The company's solutions aim to optimize sales behaviors, enhance employee performance, and mitigate risks, ultimately supporting organizations in achieving their business goals.
OptiMedica
Series C in 2008
OptiMedica Corporation, established in 2004 and based in Silicon Valley, is a global ophthalmic device company focused on enhancing patient outcomes through innovative technologies. The company is dedicated to transforming cataract surgery by developing a reproducible, noninvasive technique that utilizes femtosecond laser technology to replace traditional manual steps, which can be inconsistent. This approach aims to provide cataract surgeons with improved precision, control, performance, and efficacy. OptiMedica has conducted clinical trials for its Catalys Precision Laser System, yielding promising results. Although the system is not available for sale in the United States at this time, OptiMedica anticipates launching it in both U.S. and international markets.
Labcyte
Series C in 2008
Labcyte Inc. is a laboratory instrumentation company based in San Jose, California, specializing in acoustic droplet ejection (ADE) technology for life sciences applications. Established in 2000, Labcyte develops innovative solutions for drug discovery, genomic research, cancer research, and personalized medicine through its precise liquid dispensing technology. This technology utilizes focused acoustic energy to eject nanoliter-scale droplets of fluid, allowing for high accuracy and reduced consumption of materials. Labcyte's product offerings include automation systems, laboratory workstations, and control software aimed at enhancing research efficiency and data reliability. The company operates as a subsidiary of Beckman Coulter, Inc. and maintains additional offices across multiple countries, including Canada, the United Kingdom, and Japan.
Ciranova
Series D in 2008
Ciranova, Inc. is an electronic design automation company based in Santa Clara, California, established in 2002. The company specializes in developing interoperable tools aimed at aiding custom chip designers in the creation and migration of legacy analog intellectual property (IP). Its product offerings include PyCell Studio, which streamlines the creation of parameterized cells (PCell) and layout generators for advanced manufacturing processes, and PCell Xtreme, designed to facilitate the migration of PCells from proprietary languages into multi-vendor OpenAccess environments. Additionally, Ciranova provides services such as custom layout generator development, Python code development consulting, and analog and mixed-signal design support, enabling engineers to integrate complex RF, analog, and mixed-signal content into nanometer-scale silicon efficiently.
Retrevo
Series B in 2008
Retrevo is an online shopping platform dedicated to consumer electronics, offering a comprehensive service for product search, discovery, recommendations, and purchasing. It aggregates and analyzes information from various sources, including expert reviews, user feedback, and technical manuals, to provide users with insightful and objective guidance on a wide range of electronic products such as cameras, laptops, audio equipment, and more. Utilizing machine learning and big data analytics, Retrevo continually updates its offerings to ensure consumers have access to the latest information and trends in the electronics market. Competing with other consumer electronics platforms, Retrevo positions itself as a leading resource for individuals looking to make informed purchasing decisions.
AEGEA Medical
Series A in 2008
AEGEA Medical, Inc. is a medical technology company based in Menlo Park, California, focused on improving women's healthcare through innovative treatment options. The company has developed a water vapor ablation system, known as Mara, which provides a safe and effective method for endometrial ablation to treat heavy menstrual bleeding, or menorrhagia. This FDA-approved technology allows for a straightforward, office-based procedure that typically takes only minutes to perform. AEGEA is dedicated to enhancing patient outcomes and expanding access to effective therapies, while also supporting physicians in delivering these procedures with confidence and ease. Founded in 2008, AEGEA Medical is committed to pioneering advancements in women’s health.
LightPole
Series A in 2008
LightPole is designed to give you information you're interested in about points of interest (POI)—locations such as your current location or locations you're traveling to. For any location, LightPole is designed to answer the most probable questions in the shortest amount of time and with the least amount of interaction.
ViVOtech
Series C in 2008
ViVOtech, Inc. specializes in providing software and hardware solutions for the Near Field Communication (NFC) mobile payment and promotion market. Founded in 2001, the company offers a range of products, including NFC payment software, smart posters, contactless readers, and over-the-air card provisioning systems. Its ViVOnfc software facilitates mobile payments and promotions, while the ViVOplatform supports retailers with tools for promotional and loyalty applications. ViVOtech's solutions cater to various sectors, including movie theaters, fast food outlets, convenience stores, and transportation services, enabling merchants, banks, and wireless operators to enhance their value propositions. In October 2012, Sequent Software, Inc. acquired ViVOtech's Software Division, further integrating its innovative technologies into the broader NFC ecosystem.
Ravenflow
Venture Round in 2008
Ravenflow specializes in business requirements definition software that accelerates the application development process for enterprises. Its flagship product, RAVEN, facilitates requirements elicitation and definition, enabling stakeholders to reach consensus more quickly and reducing approval times for specifications. By minimizing developer rework caused by requirements errors, RAVEN integrates seamlessly with various application lifecycle management platforms, enhancing the overall efficiency of project delivery. The software helps business analysts visualize and validate requirements, produce specifications for business process workflows and use cases, and address specific application needs. Additionally, Ravenflow offers training and professional services to support its clients across multiple sectors, including finance, banking, insurance, government, telecommunications, technology, healthcare, education, and independent software vendors.
Ensenda
Venture Round in 2008
Ensenda is a prominent third-party logistics provider specializing in local delivery services across North America. The company operates a comprehensive network of local carriers that facilitate home and commercial deliveries, catering to various industries, including furniture retail, industrial supply, printing, office supplies, electronics, and logistics. With a focus on enhancing the delivery experience, Ensenda addresses a critical segment of the supply chain often overlooked by businesses. The local delivery sector, valued at $46 billion, is vital for customer loyalty and sales, as it encompasses the final step in the transportation process. Ensenda's diverse range of delivery programs is available in every market throughout the United States and Canada, positioning the company as a leader in this essential industry.
Arbor Surgical Technologies
Series C in 2008
Arbor Surgical Technologies, Inc. located in Irvine and Portola Valley, CA (USA), is a privately held cardiovascular medical device company focused on the heart valve replacement market. Founded in 2002 by Dr. Thomas J. Fogarty and noted heart valve designer, Ernie Lane, Arbor is developing multiple technologies that have the potential to deliver significant clinical benefit to patients worldwide. Arbor intends to develop and commercialize its core technologies in varying combinations, giving the company the opportunity to create a portfolio of product offerings. Currently in clinical trials, Arbor is developing a tissue heart valve family of products designed for improved performance over existing valves and compatible implantation tools that simplify and speed valve replacement surgery.
Zest Labs
Venture Round in 2007
Zest Labs specializes in providing on-demand data visibility solutions focused on cold chain and asset management. The company offers advanced XC3 Extended Capability RFID products and technologies that facilitate temperature monitoring for perishable food and pharmaceuticals, as well as asset tracking for construction sites and remote works. Its solutions extend to vehicle and yard management, security, and access control. Through real-time monitoring, Zest Labs helps organizations minimize shrinkage, optimize asset management, lower operational costs, and enhance profitability. In addition, the company provides post-harvest freshness management services aimed at modernizing the food distribution system, which includes tags and readers for tracking reusable transport items and personnel, ultimately improving food quality, reducing waste, and benefiting the environment.
Qwaq
Venture Round in 2007
Qwaq was renamed to Teleplace and is now 3D Immersive Collaboration Consulting. See www.3dicc.com. Qwaq is a company building enterprise applications that use 3D virtual environments for realtime collaboration and conferencing. Qwaq's flagship product, Qwaq forums, includes built-in voice communication and text chat, as well as the ability for users to share existing applications. The underlying system is built on top of Croquet, an open source 3D space system manager. Users begin as they enter a virtual room, occupied by other users and objects like tables and posters on the walls. Many of those objects are standard desktop items -- a poster on the wall, for example, might be a Word document or Excel spreadsheet. When users click on the poster from "across" the room, or access it via keyboard shortcut, it expands to fill up their screen. In addition to chatting with the other users, users can add or subtract objects, or move through different rooms as desired. Qwaq Forums is designed for business computers, which tend to be less powerful than home computers. France based [Tixeo](http://www.tixeo.com/), is another start-up focused on the same market. A slew of other companies offering tools to set up and collaborate in virtual worlds include [Second Life](http://www.crunchbase.com/organization/secondlife), [VastPark](http://www.vastpark.com/), [ProtonMedia](http://www.protonmedia.com/), [Forterra Systems](http://www.forterrainc.com/), and [Multiverse](http://www.crunchbase.com/organization/Multiverse).
AnaptysBio
Series B in 2007
AnaptysBio, Inc. is a clinical-stage biotechnology company based in San Diego, California, focused on developing therapeutic antibodies for inflammation and immuno-oncology. The company’s key product candidates include Etokimab, an anti-IL-33 treatment for atopic dermatitis, eosinophilic asthma, and chronic rhinosinusitis; ANB019, an anti-IL-36 receptor for generalized pustular psoriasis; and several immune cell modulating antibodies, including checkpoint agonists for autoimmune diseases. AnaptysBio's pipeline features notable immuno-oncology candidates such as TSR-042 (anti-PD-1), TSR-022 (anti-TIM-3), and TSR-075 (anti-PD-1/LAG-3 bispecific). The company employs a proprietary platform based on somatic hypermutation for antibody discovery and optimization, addressing unmet medical needs in therapeutic applications. AnaptysBio has formed partnerships with various organizations, including TESARO and Celgene, to enhance its research and development efforts. Founded in 2005, AnaptysBio has established itself in the biotechnology sector as a developer of innovative therapies targeting significant health challenges.
Xangati
Series B in 2007
Xangati, Inc. specializes in IT operations analytics and performance management for virtualized, private, and hybrid-cloud environments. Established in 2003 and headquartered in San Jose, California, Xangati offers a service assurance analytics framework that operates within the systems administrator's hypervisor, delivering highly granular performance metrics. The company's core products, including Xangati ESP for Cloud Workspace and Cloud Infrastructure, enable effective monitoring of application performance and capacity utilization while providing insights through cross-referenced application-level metrics and physical device interdependencies. Xangati's solutions facilitate the identification, analysis, and remediation of performance issues, helping organizations optimize their IT infrastructure and enhance end-user experience. The company serves a diverse clientele, including enterprises, government agencies, healthcare organizations, academic institutions, and cloud service providers, and has been utilized by notable clients such as Comcast and Harvard University. As of October 2016, Xangati operates as a subsidiary of Virtual Instruments Corporation.
Restoration Robotics
Series B in 2007
Restoration Robotics is a privately held medical device company focused on advancing hair transplantation technology. It has developed the ARTAS™ System, an innovative image-guided platform that facilitates follicular unit extraction, enhancing the precision and efficiency of hair restoration procedures. By integrating advanced imaging and robotics, Restoration Robotics aims to improve outcomes for patients seeking hair transplants, positioning itself as a leader in the evolving field of hair restoration. The company is committed to transforming traditional practices through its state-of-the-art technology.
KFx Medical
Series B in 2007
KFx Medical specializes in developing and manufacturing innovative soft tissue fixation implants tailored for orthopedic sports medicine. The company offers a range of products designed for tissue fixation, which can be directly placed into bones with or without sutures. These implants are applicable in various orthopedic surgical procedures, allowing surgeons to effectively reattach tissue in regions such as the shoulder, knee, foot, and ankle. KFx Medical collaborates closely with leading orthopedic surgeons to create advanced technologies and reliable surgical implants, ultimately aiming to improve surgical outcomes for patients.
ViVOtech
Series C in 2007
ViVOtech, Inc. specializes in providing software and hardware solutions for the Near Field Communication (NFC) mobile payment and promotion market. Founded in 2001, the company offers a range of products, including NFC payment software, smart posters, contactless readers, and over-the-air card provisioning systems. Its ViVOnfc software facilitates mobile payments and promotions, while the ViVOplatform supports retailers with tools for promotional and loyalty applications. ViVOtech's solutions cater to various sectors, including movie theaters, fast food outlets, convenience stores, and transportation services, enabling merchants, banks, and wireless operators to enhance their value propositions. In October 2012, Sequent Software, Inc. acquired ViVOtech's Software Division, further integrating its innovative technologies into the broader NFC ecosystem.
Adzilla
Series A in 2007
Adzilla operates a technology platform that enables internet service providers (ISPs) to deliver targeted advertising based on action-based behavioral and demographic information to publisher sites and advertising networks.
Apptera
Series D in 2007
Apptera is a mobile communications and advertising company that specializes in delivering multimedia content and interactive experiences to mobile devices. Its flagship product, Raved, enhances consumer engagement while the Apptera MobileAd Network connects advertisers with a diverse array of publishers, enabling effective outreach to millions of mobile users. The company collaborates with notable partners such as AOL Moviefone and Movietickets.com to maximize advertising impact. Founded in 2001 and based in Silicon Valley, Apptera has received several industry accolades, including recognition as one of the OnMobile 100 Top Private Companies in 2011. The company also holds multiple patents related to its communications technology, underscoring its innovative approach in the mobile advertising space. Apptera maintains additional offices in New York and Los Angeles, reflecting its expansive operational footprint.
3Leaf
Series B in 2007
3Leaf Systems specializes in server virtualization solutions that enhance corporate data center initiatives, focusing on power management and optimized scale-out architectures. Their Virtual Compute Environment (VCE) architecture provides system-level virtualization, allowing organizations to achieve mainframe-class capabilities on commodity servers. By utilizing 3Leaf's technology, businesses can significantly lower their infrastructure and operational costs while enabling rapid deployment and provisioning of data center resources. This ensures that organizations can meet the demands of modern applications effectively.
Hightail
Series B in 2007
Hightail, Inc. is a cloud services company that specializes in file sharing and creative collaboration, enabling professionals to share large files such as videos, designs, artwork, and presentations. Founded in 2004 and based in Campbell, California, Hightail offers a platform that enhances visual project management by allowing users to preview files, comment, assign tasks, and manage versions visually. The company serves a diverse clientele, including agencies, creative and marketing departments, and businesses worldwide. Hightail also provides digital transformation services, focusing on data organization and content protection through various business processes. In 2013, Hightail rebranded from its original name, YouSendIt, and it operates as a subsidiary of Open Text Corporation.
Xactly
Series C in 2007
Xactly is a prominent global provider of cloud-based Sales Performance Management solutions designed to enhance the effectiveness of sales organizations. The company specializes in planning and managing sales quotas, territories, and incentive compensation, while also offering predictive analytics to inform strategic decision-making. Its software platform enables employers to design and automate compensation plans that align employee incentives with business objectives. By delivering error-free commission payments and on-demand visibility, Xactly fosters employee trust and loyalty, thereby improving operational efficiencies and productivity. The company's solutions aim to optimize sales behaviors, enhance employee performance, and mitigate risks, ultimately supporting organizations in achieving their business goals.
Mavenir
Series B in 2007
Mavenir develops a cloud-native network software, a mobile communications software stack that runs on cloud infrastructure and connects devices, as well as people to the internet and apps, thereby offering multimedia messaging for connectivity among people.
Cambridge Heart
Post in 2007
Cambridge Heart, Inc. specializes in the research, development, and commercialization of non-invasive diagnostic products for cardiac disease. The company offers several key products, including the Heartwave II System, designed for Microvolt T-Wave Alternans (MTWA) testing, and the CH2000 Cardiac Stress Test System, which supports various standard and customized protocols for cardiac exercise stress testing. Additionally, Cambridge Heart provides Micro-V Alternans Sensors, single-use multi-segment electrodes used in MTWA tests. Its products are marketed primarily to cardiology group practices, hospitals, and research institutions, both in the United States and internationally through independent distributors. Founded in 1990, the company is headquartered in Tewksbury, Massachusetts.
Cambrios Technologies
Series C in 2007
Cambrios Technologies Corporation specializes in developing and manufacturing advanced electronic materials, particularly electrodes made from silver nanowires. These materials simplify the manufacturing processes for electronic devices while enhancing their performance. The company's flagship product, ClearOhm, consists of silver nanowire coating materials that create transparent conducting layers on various substrates. This technology is applicable to a wide range of products, including touch screens, liquid crystal displays, e-paper, organic light-emitting diodes (OLED), and thin film photovoltaics. Founded in 2002 as Semzyme, Inc., the company rebranded to Cambrios Technologies Corporation in 2004 and is headquartered in Sunnyvale, California, with additional offices in Japan and Taiwan. Cambrios aims to leverage its nanostructured materials to improve the efficiency and capabilities of next-generation consumer devices.
Teradici
Series B in 2007
Teradici Corporation specializes in PC-over-IP (PCoIP) technology, which facilitates the transmission of software images from central servers or workstations to various PCoIP-ready endpoints. This technology enhances the management and provisioning of computing services, supporting diverse work styles including local, remote, and mobile environments. Teradici offers a range of PCoIP solutions, including zero clients, optimized thin clients, hardware accelerators, remote workstation cards, and workstation access software, all designed to provide high-definition, secure computing experiences. The company's offerings also include cloud solutions such as desktop virtualization infrastructure and remote workstation services, along with optimization and monitoring tools. Teradici serves a wide array of clients, including Fortune 500 companies, educational institutions, government agencies, and cloud service providers, and collaborates with OEM partners globally. Founded in 2004 and headquartered in Burnaby, Canada, Teradici emphasizes innovation and has secured over 40 patents to date.
PacBio
Series D in 2007
PacBio designs, develops, and manufactures sequencing systems to resolve genetically complex problems. Its single molecule real-time (SMRT) sequencing technology enables single molecule real-time detection of biological processes.
Standard BioTools
Series E in 2007
Standard BioTools, previously known as Fluidigm, is driven by a bold vision – unleashing tools to accelerate breakthroughs in human health. Standard BioTools has an established portfolio of essential, standardized next-generation technologies that help biomedical researchers develop medicines faster and better. As a leading solutions provider, the Company provides reliable and repeatable insights in health and disease using its proprietary mass cytometry and microfluidics technologies that help transform scientific discoveries into better patient outcomes. Standard BioTools works with leading academic, government, pharmaceutical, biotechnology, plant and animal research, and clinical laboratories worldwide, focusing on the most pressing needs in translational and clinical research, including oncology, immunology, and immunotherapy.
Codon Devices
Series B in 2006
Codon Devices is a biotechnology company, engages in developing, constructing, and delivering synthetic biology products for research. The company focuses on discovering and manufacturing synthetic biological parts. Its BioLOGIC Engineering Platform combines sophisticated design algorithms with assay and protein engineering capabilities to result in a system for the design, discovery, and optimization of proteins for specific applications; and BioFAB Production Platform, which produces synthetic genes.
MontaVista Software
Venture Round in 2006
MontaVista Software specializes in the commercialization of embedded Linux, focusing on providing businesses with high-quality Linux solutions and developer tools tailored for various applications, including industrial automation, automotive, and multimedia devices. Their offerings include Market Specific Distributions (MSDs), which help streamline the development process and reduce the time needed to bring products to market. With a commitment to leveraging open source technology, MontaVista Software also provides expert support and hardware enablement, fostering a strong community around its solutions. As a result, over 50 million devices currently operate on MontaVista Linux, demonstrating the company's significant impact on the embedded device market.
Retrevo
Series A in 2006
Retrevo is an online shopping platform dedicated to consumer electronics, offering a comprehensive service for product search, discovery, recommendations, and purchasing. It aggregates and analyzes information from various sources, including expert reviews, user feedback, and technical manuals, to provide users with insightful and objective guidance on a wide range of electronic products such as cameras, laptops, audio equipment, and more. Utilizing machine learning and big data analytics, Retrevo continually updates its offerings to ensure consumers have access to the latest information and trends in the electronics market. Competing with other consumer electronics platforms, Retrevo positions itself as a leading resource for individuals looking to make informed purchasing decisions.
Hightail
Series A in 2006
Hightail, Inc. is a cloud services company that specializes in file sharing and creative collaboration, enabling professionals to share large files such as videos, designs, artwork, and presentations. Founded in 2004 and based in Campbell, California, Hightail offers a platform that enhances visual project management by allowing users to preview files, comment, assign tasks, and manage versions visually. The company serves a diverse clientele, including agencies, creative and marketing departments, and businesses worldwide. Hightail also provides digital transformation services, focusing on data organization and content protection through various business processes. In 2013, Hightail rebranded from its original name, YouSendIt, and it operates as a subsidiary of Open Text Corporation.
Polimetrix
Series A in 2006
Polimetrix engages in survey research and analytics for research needs. The company provides BrandIndex, an information product that collects responses and calculates BIX net metrics based on the responses. It offers consulting, online survey, and online qualitative services. Polimetrix conducts surveys and polls for democratic, republican, and independent consultants; market research agencies; corporate public affairs groups; media organizations; university researchers; and non-profit organizations through its Website. The company was founded in 2004 and is headquartered in Palo Alto, California. Polimetrix, Inc. operates as a subsidiary of YouGov PLC.
Attune Systems
Venture Round in 2006
Attune Systems, Inc. specializes in network file management solutions aimed at simplifying file management for enterprise, government, and educational sectors. The company offers the Maestro File Manager, a file virtualization appliance designed to assist IT administrators in discovering, analyzing, managing, and optimizing heterogeneous file storage resources. In addition to file management, Attune Systems provides services such as archive intelligence, security diligence, data migration and consolidation, disaster recovery, forensic search, and tiered backup and storage with deduplication. Founded in 1999 and headquartered in Santa Clara, California, the company has established strategic partnerships with prominent technology firms including Microsoft, Data Domain, NetApp, Symantec, and Google. However, it has recently experienced significant changes and has become less prominent in the industry.
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