Alloy Ventures

Agari is a company focused on email security, specializing in the protection of brands and individuals from phishing and socially-engineered attacks. By leveraging applied data science and a variety of signals, Agari safeguards organizations against threats such as business email compromise, supply chain fraud, and account takeovers, thereby reducing business risks and restoring confidence in email communications. The company's platform is designed to enhance the security of inbound emails while also preventing the spoofing of outbound communications, which helps maintain brand integrity and improve email deliverability. Through its innovative approach, Agari enables safe interactions between businesses and their customers, effectively eliminating email as a vector for cyber-attacks.

AEGEA Medical, Inc. is a medical technology company based in Menlo Park, California, that specializes in innovative treatments for women's health. The company has developed a water vapor ablation system, known as Mara, which is designed for the in-office treatment of heavy menstrual bleeding, specifically menorrhagia. This FDA-approved technology utilizes adaptive vapor ablation to deliver safe and effective endometrial ablation in a simple procedure that takes only minutes. AEGEA Medical aims to expand treatment options for a broader range of patients while ensuring convenience and confidence for physicians performing these office-based procedures. The company was incorporated in 2007 and continues to focus on enhancing patient outcomes in women's healthcare.

Agari is a company focused on email security, specializing in the protection of brands and individuals from phishing and socially-engineered attacks. By leveraging applied data science and a variety of signals, Agari safeguards organizations against threats such as business email compromise, supply chain fraud, and account takeovers, thereby reducing business risks and restoring confidence in email communications. The company's platform is designed to enhance the security of inbound emails while also preventing the spoofing of outbound communications, which helps maintain brand integrity and improve email deliverability. Through its innovative approach, Agari enables safe interactions between businesses and their customers, effectively eliminating email as a vector for cyber-attacks.

AEGEA Medical, Inc. is a medical technology company based in Menlo Park, California, that specializes in innovative treatments for women's health. The company has developed a water vapor ablation system, known as Mara, which is designed for the in-office treatment of heavy menstrual bleeding, specifically menorrhagia. This FDA-approved technology utilizes adaptive vapor ablation to deliver safe and effective endometrial ablation in a simple procedure that takes only minutes. AEGEA Medical aims to expand treatment options for a broader range of patients while ensuring convenience and confidence for physicians performing these office-based procedures. The company was incorporated in 2007 and continues to focus on enhancing patient outcomes in women's healthcare.

Restoration Robotics is a privately held medical device company focused on advancing hair transplantation technology. It has developed the ARTAS™ System, an innovative image-guided platform that facilitates follicular unit extraction, enhancing the precision and efficiency of hair restoration procedures. By integrating advanced imaging and robotics, Restoration Robotics aims to improve outcomes for patients seeking hair transplants, positioning itself as a leader in the evolving field of hair restoration. The company is committed to transforming traditional practices through its state-of-the-art technology.

Agari is a company focused on email security, specializing in the protection of brands and individuals from phishing and socially-engineered attacks. By leveraging applied data science and a variety of signals, Agari safeguards organizations against threats such as business email compromise, supply chain fraud, and account takeovers, thereby reducing business risks and restoring confidence in email communications. The company's platform is designed to enhance the security of inbound emails while also preventing the spoofing of outbound communications, which helps maintain brand integrity and improve email deliverability. Through its innovative approach, Agari enables safe interactions between businesses and their customers, effectively eliminating email as a vector for cyber-attacks.

GigaOm is a media company that specializes in providing news, analysis, and opinions on startups and emerging technologies. Founded in 2006 by Om Malik and based in San Francisco, GigaOm aims to humanize technology and offer deep insights into disruptive companies and trends. The company attracts over 6.5 million unique monthly readers who rely on its content to comprehend significant technological disruptions and the business opportunities that arise from them. GigaOm's information is produced by a network of more than 200 independent analysts, who deliver timely content bridging breaking news and long-term research. Additionally, GigaOm hosts events that combine focused editorial content with opportunities for attendees to engage with technology disruptors, equipping them with the tools needed to capitalize on emerging trends. The company serves both individual and corporate subscribers, making it a valuable resource for those seeking in-depth analysis of the technology landscape.

Grand Junction, Inc. is a technology company based in San Francisco, California, that specializes in Software-as-a-Service solutions for local delivery management. Founded in 2000, the company has developed a comprehensive platform that facilitates access to same-day delivery services across all markets in the United States and Canada. With a network of 700 local carriers, Grand Junction enables small to medium-sized businesses, large enterprises, and individual consumers to efficiently manage deliveries. The platform offers various customizable options, including on-demand, same-day, scheduled, and two-person delivery services. Grand Junction's technology not only enhances the customer experience through features like real-time visibility and GPS alerts but also significantly reduces delivery costs for its users. Having managed nearly 100 million deliveries to date, Grand Junction stands out as a leader in the local delivery sector.

Hightail, Inc. is a cloud services company that specializes in file sharing and creative collaboration, enabling professionals to share large files such as videos, designs, artwork, and presentations. Founded in 2004 and based in Campbell, California, Hightail offers a platform that enhances visual project management by allowing users to preview files, comment, assign tasks, and manage versions visually. The company serves a diverse clientele, including agencies, creative and marketing departments, and businesses worldwide. Hightail also provides digital transformation services, focusing on data organization and content protection through various business processes. In 2013, Hightail rebranded from its original name, YouSendIt, and it operates as a subsidiary of Open Text Corporation.

Scifiniti is an early-stage company focused on developing innovative crystalline silicon materials technology. Their core business involves creating a direct, high-quality silicon wafer for solar cells, bypassing traditional polysilicon casting and sawing processes. This approach aims to enhance performance and reduce costs in silicon-based products for energy markets, offering businesses a low-cost, drop-in replacement photovoltaic silicon wafer to produce more efficient solar modules.

OptiMedica Corporation is a Silicon Valley-based ophthalmic device company established in 2004, focused on advancing technologies to enhance patient outcomes in eye care. The company specializes in developing a noninvasive, reproducible technique that utilizes femtosecond laser technology to improve the precision and consistency of cataract surgery, addressing the limitations of traditional manual methods. OptiMedica's flagship product, the Catalys Precision Laser System, has undergone successful clinical trials, demonstrating significant improvements in performance and efficacy for cataract surgeons and their patients. Although the system is not yet available for sale in the United States, OptiMedica aims to launch it in both U.S. and international markets.

RainDance Technologies, Inc. specializes in developing advanced genomic tools for non-invasive liquid biopsy applications, focusing on cancer detection, treatment, and the study of inherited and infectious diseases. The company's flagship product, the RainDrop digital polymerase chain reaction platform, utilizes picoliter-sized droplets to facilitate multiplex detection of genetic material, including DNA and RNA. Additionally, RainDance offers the RainDrop Plus digital PCR system, which integrates next-generation sequencing (NGS) amplicon enrichment with digital PCR capabilities. Their automated ThunderStorm solution enhances NGS content enrichment, allowing laboratories to process multiple samples efficiently while ensuring high-quality data. The ThunderBolts panels target critical cancer mutations and specific genetic markers associated with myeloid disorders. RainDance's products include a range of consumables designed to optimize various laboratory processes. Founded in 2004 and headquartered in Billerica, Massachusetts, the company serves research institutions and laboratories globally through a network of sales representatives and distributors. RainDance Technologies operates as a subsidiary of Bio-Rad Laboratories, Inc.

Labcyte Inc., founded in 2000 and based in San Jose, California, specializes in developing acoustic droplet ejection (ADE) technology for various applications in the life sciences. The company's innovative approach uses focused beams of acoustic energy to precisely dispense nanoliter-scale droplets of fluid from one plate to another, enabling high accuracy at low volumes and reducing consumables costs. Labcyte's products include automation systems, laboratory workstations, and control software, which are utilized in drug discovery, genomics research, cancer research, and personalized medicine. The company operates as a subsidiary of Beckman Coulter, Inc., with additional offices across multiple countries including Canada, the United Kingdom, Australia, India, South Korea, China, Hong Kong, Japan, Singapore, and Taiwan.

Genomatica, Inc. is a biotechnology company based in San Diego, California, specializing in the development of manufacturing processes for intermediate and basic chemicals derived from renewable feedstocks. Founded in 1998, the company utilizes its proprietary biotechnology platform to create fermentation-based processes and to engineer microorganisms that facilitate the conversion of these feedstocks into essential chemicals. Genomatica has successfully commercialized processes for chemicals such as butanediol, which is used in biodegradable plastics and apparel, and butylene glycol, commonly found in cosmetics and personal care products. The company is also actively working on bio-nylon and has developed a pipeline targeting the production of 20 different chemicals. Recognized for its innovative technologies, Genomatica has received numerous accolades, including the Kirkpatrick Award for outstanding chemical engineering technology and the ICIS Innovation Award for its Brontide butylene glycol.

Siluria Technologies is a materials innovation company focused on addressing global challenges in the natural gas, chemicals, and fuel industries. By leveraging advancements in nanotechnology, biotechnology, and chemical engineering, Siluria has created a platform that enables the efficient production of chemicals and fuels from natural gas, a more abundant and cost-effective resource compared to oil. Their technology allows for the conversion of natural gas into higher-value products, including liquid fuels such as gasoline, diesel, and jet fuel, through the integration of nanomaterials and catalyst development. Siluria's research and engineering teams are actively working to commercialize their solutions and engage with major chemical and fuel companies to bring their technology to pilot-scale production.

Ensenda is a prominent third-party logistics provider specializing in local delivery services across North America. The company offers a comprehensive range of logistics solutions for various sectors, including home and commercial delivery, catering to industries such as furniture retail, industrial supply, printing, office supplies, electronics, and logistics. With a robust network of local carriers, Ensenda ensures efficient and timely delivery, addressing the critical last-mile challenges that significantly impact customer satisfaction and loyalty. By focusing on enhancing the delivery experience, Ensenda plays a vital role in optimizing supply chain operations for its clients.

Agari is a company focused on email security, specializing in the protection of brands and individuals from phishing and socially-engineered attacks. By leveraging applied data science and a variety of signals, Agari safeguards organizations against threats such as business email compromise, supply chain fraud, and account takeovers, thereby reducing business risks and restoring confidence in email communications. The company's platform is designed to enhance the security of inbound emails while also preventing the spoofing of outbound communications, which helps maintain brand integrity and improve email deliverability. Through its innovative approach, Agari enables safe interactions between businesses and their customers, effectively eliminating email as a vector for cyber-attacks.

Siluria Technologies is a materials innovation company focused on addressing global challenges in the natural gas, chemicals, and fuel industries. By leveraging advancements in nanotechnology, biotechnology, and chemical engineering, Siluria has created a platform that enables the efficient production of chemicals and fuels from natural gas, a more abundant and cost-effective resource compared to oil. Their technology allows for the conversion of natural gas into higher-value products, including liquid fuels such as gasoline, diesel, and jet fuel, through the integration of nanomaterials and catalyst development. Siluria's research and engineering teams are actively working to commercialize their solutions and engage with major chemical and fuel companies to bring their technology to pilot-scale production.

Verinata Health is a company dedicated to improving maternal and fetal health through the development of non-invasive tests designed for the early identification of fetal chromosomal abnormalities. Utilizing proprietary technologies, Verinata focuses on analyzing cell-free DNA in maternal blood to provide pregnant women with a safe, accurate, and definitive assessment of fetal aneuploidy. This approach aims to alleviate the anxiety associated with traditional multi-step prenatal screening methods, which often have high false-positive rates and can yield confusing results. By offering a single blood draw test, Verinata seeks to fulfill the recommendations for first trimester aneuploidy risk assessment, thereby enhancing the overall experience for expectant mothers. The company is actively conducting a prospective, blinded pivotal study to validate the sensitivity and specificity of its first prenatal test on a large scale, with results anticipated in the near future.

Restoration Robotics is a privately held medical device company focused on advancing hair transplantation technology. It has developed the ARTAS™ System, an innovative image-guided platform that facilitates follicular unit extraction, enhancing the precision and efficiency of hair restoration procedures. By integrating advanced imaging and robotics, Restoration Robotics aims to improve outcomes for patients seeking hair transplants, positioning itself as a leader in the evolving field of hair restoration. The company is committed to transforming traditional practices through its state-of-the-art technology.

Crux Biomedical, Inc. was founded in August 2004 by physicians Tom Fogarty and Frank Arko, who aimed to address the clinical limitations of existing vena cava filters. The company specializes in the development of the Crux VCF System, a preventive device designed to mitigate the risk of pulmonary embolisms. This innovative system effectively prevents blood clots from traveling to the lungs, making it particularly beneficial for patients who are at risk of pulmonary embolism but are unable to tolerate blood thinners. Through its focus on improving patient outcomes, Crux Biomedical addresses a critical need in the management of venous thromboembolism.

Infineta Systems is a privately-held network infrastructure company that develops and markets a line of high-performance network optimization products. Infineta’s system architecture will power a generation of products to address the urgent need for high-speed enterprise data center interconnects. Infineta is pioneering a new category of products that will help Global 2000 enterprises address the explosion in inter-data center traffic resulting from mission-critical storage replication, backup and emerging “private cloud” applications. At the center of this architecture is Infineta’s patent-pending Velocity Dedupe Engine™. The Velocity Dedupe Engine is providing an innovative, hardware-based solution to obtain the high throughput and zero-latency requirements necessary for today’s enterprise data centers. Infineta offers customers dramatically lower costs and more control of their critical data center-to-data center traffic. Customers leverage the Infineta solution to build high-performance inter-data center fabric, transforming a rigid and inflexible model into an agile ‘global area network’ of pooled resources for a more powerful and cost-effective computing experience.

Mavenir is a cloud-native network software provider that focuses on transforming telecommunications networks for Communications Service Providers (CSPs). The company offers a comprehensive suite of products that spans all layers of network infrastructure, including 5G application layers, packet core, and radio access networks (RAN). With a track record of pioneering advanced technologies such as VoLTE and Virtualized RAN, Mavenir serves over 250 CSP customers in more than 130 countries, impacting over 50% of global subscribers. Their innovative solutions are designed to enhance service agility and reduce costs while promoting revenue generation and protection. By leveraging disruptive technology architectures, Mavenir aims to redefine network economics and accelerate the evolution of network functions virtualization (NFV) to achieve web-scale efficiencies.

AEGEA Medical, Inc. is a medical technology company based in Menlo Park, California, that specializes in innovative treatments for women's health. The company has developed a water vapor ablation system, known as Mara, which is designed for the in-office treatment of heavy menstrual bleeding, specifically menorrhagia. This FDA-approved technology utilizes adaptive vapor ablation to deliver safe and effective endometrial ablation in a simple procedure that takes only minutes. AEGEA Medical aims to expand treatment options for a broader range of patients while ensuring convenience and confidence for physicians performing these office-based procedures. The company was incorporated in 2007 and continues to focus on enhancing patient outcomes in women's healthcare.

GigaOm is a media company that specializes in providing news, analysis, and opinions on startups and emerging technologies. Founded in 2006 by Om Malik and based in San Francisco, GigaOm aims to humanize technology and offer deep insights into disruptive companies and trends. The company attracts over 6.5 million unique monthly readers who rely on its content to comprehend significant technological disruptions and the business opportunities that arise from them. GigaOm's information is produced by a network of more than 200 independent analysts, who deliver timely content bridging breaking news and long-term research. Additionally, GigaOm hosts events that combine focused editorial content with opportunities for attendees to engage with technology disruptors, equipping them with the tools needed to capitalize on emerging trends. The company serves both individual and corporate subscribers, making it a valuable resource for those seeking in-depth analysis of the technology landscape.

Cameron Health, Inc. is a development stage medical device company focused on creating innovative implantable electronic devices. With a team of experienced professionals, the company specializes in the development and manufacturing of subcutaneous implantable defibrillator (S-ICD) systems, designed for patients at risk of ventricular tachyarrhythmias. The S-ICD system includes key components such as the SQ-RX pulse generator, which delivers electrical pulses to manage cardiac arrhythmias, and the Q-TRAK subcutaneous electrode, implanted parallel to the left sternal border. Additionally, the Q-TECH programmer wirelessly communicates with the SQ-RX device, enhancing patient management. Cameron Health aims to provide advanced treatment options that were previously unattainable, leveraging state-of-the-art technologies to address complex medical challenges.

RainDance Technologies, Inc. specializes in developing advanced genomic tools for non-invasive liquid biopsy applications, focusing on cancer detection, treatment, and the study of inherited and infectious diseases. The company's flagship product, the RainDrop digital polymerase chain reaction platform, utilizes picoliter-sized droplets to facilitate multiplex detection of genetic material, including DNA and RNA. Additionally, RainDance offers the RainDrop Plus digital PCR system, which integrates next-generation sequencing (NGS) amplicon enrichment with digital PCR capabilities. Their automated ThunderStorm solution enhances NGS content enrichment, allowing laboratories to process multiple samples efficiently while ensuring high-quality data. The ThunderBolts panels target critical cancer mutations and specific genetic markers associated with myeloid disorders. RainDance's products include a range of consumables designed to optimize various laboratory processes. Founded in 2004 and headquartered in Billerica, Massachusetts, the company serves research institutions and laboratories globally through a network of sales representatives and distributors. RainDance Technologies operates as a subsidiary of Bio-Rad Laboratories, Inc.

GigaOm is a media company that specializes in providing news, analysis, and opinions on startups and emerging technologies. Founded in 2006 by Om Malik and based in San Francisco, GigaOm aims to humanize technology and offer deep insights into disruptive companies and trends. The company attracts over 6.5 million unique monthly readers who rely on its content to comprehend significant technological disruptions and the business opportunities that arise from them. GigaOm's information is produced by a network of more than 200 independent analysts, who deliver timely content bridging breaking news and long-term research. Additionally, GigaOm hosts events that combine focused editorial content with opportunities for attendees to engage with technology disruptors, equipping them with the tools needed to capitalize on emerging trends. The company serves both individual and corporate subscribers, making it a valuable resource for those seeking in-depth analysis of the technology landscape.

Siluria Technologies is a materials innovation company focused on addressing global challenges in the natural gas, chemicals, and fuel industries. By leveraging advancements in nanotechnology, biotechnology, and chemical engineering, Siluria has created a platform that enables the efficient production of chemicals and fuels from natural gas, a more abundant and cost-effective resource compared to oil. Their technology allows for the conversion of natural gas into higher-value products, including liquid fuels such as gasoline, diesel, and jet fuel, through the integration of nanomaterials and catalyst development. Siluria's research and engineering teams are actively working to commercialize their solutions and engage with major chemical and fuel companies to bring their technology to pilot-scale production.

Ciranova, Inc. is an electronic design automation company headquartered in Santa Clara, California, established in 2002. The company specializes in developing interoperable tools for custom chip designers, enabling the creation and migration of legacy analog intellectual property (IP). Ciranova offers products such as PyCell Studio, which streamlines the processes of PCell and layout generator creation for deep submicron technologies, and PCell Xtreme, which facilitates the transition of PCells written in proprietary languages to multi-vendor OpenAccess environments. In addition to its software solutions, Ciranova provides a range of consulting services, including custom layout generator development, Python code development, layout consulting, and analog and mixed-signal design services, helping engineers integrate complex RF and analog content into high-density, high-speed nanometer-scale silicon.

Xactly is a prominent global provider of cloud-based Sales Performance Management solutions designed to enhance the effectiveness of sales organizations. The company specializes in planning and managing sales quotas, territories, and incentive compensation, while also offering predictive analytics to inform strategic decision-making. Its software platform enables employers to design and automate compensation plans that align employee incentives with business objectives. By delivering error-free commission payments and on-demand visibility, Xactly fosters employee trust and loyalty, thereby improving operational efficiencies and productivity. The company's solutions aim to optimize sales behaviors, enhance employee performance, and mitigate risks, ultimately supporting organizations in achieving their business goals.

Hightail, Inc. is a cloud services company that specializes in file sharing and creative collaboration, enabling professionals to share large files such as videos, designs, artwork, and presentations. Founded in 2004 and based in Campbell, California, Hightail offers a platform that enhances visual project management by allowing users to preview files, comment, assign tasks, and manage versions visually. The company serves a diverse clientele, including agencies, creative and marketing departments, and businesses worldwide. Hightail also provides digital transformation services, focusing on data organization and content protection through various business processes. In 2013, Hightail rebranded from its original name, YouSendIt, and it operates as a subsidiary of Open Text Corporation.

Pacific Biosciences specializes in human, microbial, plant, and animal genomics, focusing on areas such as infectious disease research. The company designs and manufactures sequencing systems that address complex genetic challenges, utilizing its innovative single molecule real-time (SMRT) sequencing technology to detect biological processes in real time. Its product offerings include the PacBio RS II and Sequel Systems, which facilitate the monitoring and analysis of biochemical reactions at the single-molecule level, along with consumables like SMRT cells and various reagent kits. Customers range from research institutions and commercial laboratories to pharmaceutical and agricultural companies, with sales conducted through direct channels in North America and Europe, and distribution partners in Asia, the Middle East, and Latin America. Founded in 2000 and headquartered in Menlo Park, California, Pacific Biosciences continues to advance genomics research and applications.

BarRx Medical, Inc. specializes in developing endoscopic treatment solutions for Barrett's esophagus and other chronic gastroenterological diseases. Barrett's esophagus is a precancerous condition resulting from gastroesophageal reflux disease (GERD). The company’s primary products include the HALOFLEX, HALO360, and HALO90 ablation systems, which utilize a balloon-based electrode to circumferentially ablate diseased tissue in the esophagus. These systems are designed to ensure a uniform and controlled ablation effect, promoting the regrowth of healthy cells. Clinical studies have demonstrated the effectiveness of the HALO systems, showing high rates of complete eradication of dysplasia and intestinal metaplasia, as well as significantly reduced disease progression and cancer development. The HALO systems are FDA-cleared for use in the United States and hold CE Mark approval for Europe, with over 58,000 procedures performed across more than 400 hospitals globally. Founded in 2000 and based in Sunnyvale, California, BarRx Medical, Inc. operates as a privately held company.

Xactly is a prominent global provider of cloud-based Sales Performance Management solutions designed to enhance the effectiveness of sales organizations. The company specializes in planning and managing sales quotas, territories, and incentive compensation, while also offering predictive analytics to inform strategic decision-making. Its software platform enables employers to design and automate compensation plans that align employee incentives with business objectives. By delivering error-free commission payments and on-demand visibility, Xactly fosters employee trust and loyalty, thereby improving operational efficiencies and productivity. The company's solutions aim to optimize sales behaviors, enhance employee performance, and mitigate risks, ultimately supporting organizations in achieving their business goals.

Mavenir is a cloud-native network software provider that focuses on transforming telecommunications networks for Communications Service Providers (CSPs). The company offers a comprehensive suite of products that spans all layers of network infrastructure, including 5G application layers, packet core, and radio access networks (RAN). With a track record of pioneering advanced technologies such as VoLTE and Virtualized RAN, Mavenir serves over 250 CSP customers in more than 130 countries, impacting over 50% of global subscribers. Their innovative solutions are designed to enhance service agility and reduce costs while promoting revenue generation and protection. By leveraging disruptive technology architectures, Mavenir aims to redefine network economics and accelerate the evolution of network functions virtualization (NFV) to achieve web-scale efficiencies.

Apptera is a mobile communications and advertising company that specializes in delivering multimedia content and interactive experiences to mobile devices. Its flagship product, Raved, enhances consumer engagement while the Apptera MobileAd Network connects advertisers with a diverse array of publishers, enabling effective outreach to millions of mobile users. The company collaborates with notable partners such as AOL Moviefone and Movietickets.com to maximize advertising impact. Founded in 2001 and based in Silicon Valley, Apptera has received several industry accolades, including recognition as one of the OnMobile 100 Top Private Companies in 2011. The company also holds multiple patents related to its communications technology, underscoring its innovative approach in the mobile advertising space. Apptera maintains additional offices in New York and Los Angeles, reflecting its expansive operational footprint.

Scifiniti is an early-stage company focused on developing innovative crystalline silicon materials technology. Their core business involves creating a direct, high-quality silicon wafer for solar cells, bypassing traditional polysilicon casting and sawing processes. This approach aims to enhance performance and reduce costs in silicon-based products for energy markets, offering businesses a low-cost, drop-in replacement photovoltaic silicon wafer to produce more efficient solar modules.

Infineta Systems is a privately-held network infrastructure company that develops and markets a line of high-performance network optimization products. Infineta’s system architecture will power a generation of products to address the urgent need for high-speed enterprise data center interconnects. Infineta is pioneering a new category of products that will help Global 2000 enterprises address the explosion in inter-data center traffic resulting from mission-critical storage replication, backup and emerging “private cloud” applications. At the center of this architecture is Infineta’s patent-pending Velocity Dedupe Engine™. The Velocity Dedupe Engine is providing an innovative, hardware-based solution to obtain the high throughput and zero-latency requirements necessary for today’s enterprise data centers. Infineta offers customers dramatically lower costs and more control of their critical data center-to-data center traffic. Customers leverage the Infineta solution to build high-performance inter-data center fabric, transforming a rigid and inflexible model into an agile ‘global area network’ of pooled resources for a more powerful and cost-effective computing experience.

Genomatica, Inc. is a biotechnology company based in San Diego, California, specializing in the development of manufacturing processes for intermediate and basic chemicals derived from renewable feedstocks. Founded in 1998, the company utilizes its proprietary biotechnology platform to create fermentation-based processes and to engineer microorganisms that facilitate the conversion of these feedstocks into essential chemicals. Genomatica has successfully commercialized processes for chemicals such as butanediol, which is used in biodegradable plastics and apparel, and butylene glycol, commonly found in cosmetics and personal care products. The company is also actively working on bio-nylon and has developed a pipeline targeting the production of 20 different chemicals. Recognized for its innovative technologies, Genomatica has received numerous accolades, including the Kirkpatrick Award for outstanding chemical engineering technology and the ICIS Innovation Award for its Brontide butylene glycol.

Integrated Photovoltaics is a leading developer of next-generation photovoltaic solutions. Integrated Photovoltaics is a privately held company headquartered in Sunnyvale, California.

Fluidigm Corporation develops and markets innovative technologies and tools for life sciences research globally. The company specializes in integrated fluidic circuits that control fluids at the nanoscale, enabling a range of applications in biological research. Its product offerings include analytical systems such as the Helios CyTOF system, the Hyperion imaging system, and the Biomark HD system, along with various assays and reagents designed for immuno-oncology and genetic analysis. Fluidigm also provides preparatory instruments and single-cell microfluidics, such as the C1 and Polaris systems. The company serves a diverse clientele, including academic institutions, clinical research laboratories, biopharmaceutical, biotechnology, and agricultural biotechnology companies, focusing on non-diagnostic and non-clinical applications. Established in 1999 as Mycometrix Corporation, it adopted the name Fluidigm Corporation in 2001 and is headquartered in South San Francisco, California.

Cambrios Technologies Corporation is a manufacturer of innovative electronic materials specializing in silver nanowire-based electrodes. Founded in 2002 and originally named Semzyme, Inc., the company rebranded in August 2004. Headquartered in Sunnyvale, California, with additional offices in Japan and Taiwan, Cambrios develops products such as ClearOhm, which are transparent conductive coatings that can be applied to various substrates for multiple applications. These include touch screens, liquid crystal displays, e-paper, OLED devices, and lighting, as well as thin film photovoltaics like organic photovoltaics and printed organic solar cells. Cambrios's technology enables simplified manufacturing processes and enhances the performance of next-generation consumer devices.

Ravenflow is a provider of business requirements definition software designed to help enterprises accelerate application delivery. The company's flagship product, RAVEN, facilitates requirements elicitation and definition, enabling stakeholders to reach consensus more quickly and reducing the time needed for approval of specifications. By minimizing developer rework due to requirements errors and integrating requirements with testing processes, Ravenflow enhances overall efficiency. The software also assists business analysts in visualizing and validating requirements, producing specifications for business process workflows, use cases, and application needs. In addition to its software offerings, Ravenflow provides training and professional services, serving a diverse range of sectors including finance, banking, insurance, government, telecommunications, technology, healthcare, and education, as well as independent software vendors and systems integrators.

Teradici Corporation specializes in PC-over-IP (PCoIP) technology, which transfers the image of software from central servers or workstations to various end-points, facilitating local, remote, mobile, and collaborative work styles. The company offers a range of PCoIP solutions, including zero clients, optimized thin clients, hardware accelerators, remote workstation cards, workstation access software, and a management console for streamlined deployment and management of PCoIP devices. Teradici's offerings extend to cloud solutions such as desktop virtualization infrastructure and Desktop as a Service, as well as optimization and monitoring tools. The company's clientele includes Fortune 500 enterprises, educational institutions, government agencies, and service providers across various sectors, including healthcare, media, manufacturing, and construction. Founded in 2004 and based in Burnaby, Canada, Teradici has developed a strong ecosystem of products and services and maintains strategic partnerships with companies like Dell Wyse and Socionext Inc. Its commitment to innovation is underscored by its significant investment in research and development, resulting in over 40 patents.

SynergEyes, Inc. is a technology-driven company specializing in the development and manufacturing of hybrid contact lenses designed to enhance vision and improve quality of life for patients. Founded in 2001 and headquartered in Carlsbad, California, SynergEyes offers innovative products that combine the visual acuity of rigid gas permeable lenses with the comfort of soft lenses. Their hybrid lenses cater to a range of eye conditions, including astigmatism, presbyopia, myopia, hyperopia, and keratoconus, utilizing advanced high-Dk materials and vision-optimized designs. The company distributes its products both domestically and internationally, emphasizing a commitment to improving eye health and transforming vision for eye care professionals and their patients.

Crux Biomedical, Inc. was founded in August 2004 by physicians Tom Fogarty and Frank Arko, who aimed to address the clinical limitations of existing vena cava filters. The company specializes in the development of the Crux VCF System, a preventive device designed to mitigate the risk of pulmonary embolisms. This innovative system effectively prevents blood clots from traveling to the lungs, making it particularly beneficial for patients who are at risk of pulmonary embolism but are unable to tolerate blood thinners. Through its focus on improving patient outcomes, Crux Biomedical addresses a critical need in the management of venous thromboembolism.

Humanigen, Inc. is a clinical-stage biopharmaceutical company based in Burlingame, California, that specializes in the development of proprietary monoclonal antibodies aimed at immunotherapy and oncology treatments. The company’s leading candidate, Lenzilumab, targets granulocyte-macrophage colony-stimulating factor and is currently undergoing Phase Ib/II clinical trials for chronic myelomonocytic leukemia and juvenile myelomonocytic leukemia. Additionally, Humanigen is developing Ifabotuzumab, which targets the EphA3 receptor and has completed the Phase I portion of a Phase I/II clinical trial for various hematologic malignancies. The company is also working on HGEN005, an anti-EMR1 monoclonal antibody in the pre-clinical stage for eosinophilic diseases. Humanigen has established collaborations, including a clinical partnership with Kite Pharma to study Lenzilumab in patients with relapsed or refractory diffuse large B-cell lymphoma and a research agreement with the Department of Defense to facilitate the development of Lenzilumab for potential emergency use in COVID-19. Formed in 2000, the company was previously known as KaloBios Pharmaceuticals and rebranded as Humanigen in 2017.

Mavenir is a cloud-native network software provider that focuses on transforming telecommunications networks for Communications Service Providers (CSPs). The company offers a comprehensive suite of products that spans all layers of network infrastructure, including 5G application layers, packet core, and radio access networks (RAN). With a track record of pioneering advanced technologies such as VoLTE and Virtualized RAN, Mavenir serves over 250 CSP customers in more than 130 countries, impacting over 50% of global subscribers. Their innovative solutions are designed to enhance service agility and reduce costs while promoting revenue generation and protection. By leveraging disruptive technology architectures, Mavenir aims to redefine network economics and accelerate the evolution of network functions virtualization (NFV) to achieve web-scale efficiencies.

Apptera is a mobile communications and advertising company that specializes in delivering multimedia content and interactive experiences to mobile devices. Its flagship product, Raved, enhances consumer engagement while the Apptera MobileAd Network connects advertisers with a diverse array of publishers, enabling effective outreach to millions of mobile users. The company collaborates with notable partners such as AOL Moviefone and Movietickets.com to maximize advertising impact. Founded in 2001 and based in Silicon Valley, Apptera has received several industry accolades, including recognition as one of the OnMobile 100 Top Private Companies in 2011. The company also holds multiple patents related to its communications technology, underscoring its innovative approach in the mobile advertising space. Apptera maintains additional offices in New York and Los Angeles, reflecting its expansive operational footprint.

Apptera is a mobile communications and advertising company that specializes in delivering multimedia content and interactive experiences to mobile devices. Its flagship product, Raved, enhances consumer engagement while the Apptera MobileAd Network connects advertisers with a diverse array of publishers, enabling effective outreach to millions of mobile users. The company collaborates with notable partners such as AOL Moviefone and Movietickets.com to maximize advertising impact. Founded in 2001 and based in Silicon Valley, Apptera has received several industry accolades, including recognition as one of the OnMobile 100 Top Private Companies in 2011. The company also holds multiple patents related to its communications technology, underscoring its innovative approach in the mobile advertising space. Apptera maintains additional offices in New York and Los Angeles, reflecting its expansive operational footprint.

Verinata Health is a company dedicated to improving maternal and fetal health through the development of non-invasive tests designed for the early identification of fetal chromosomal abnormalities. Utilizing proprietary technologies, Verinata focuses on analyzing cell-free DNA in maternal blood to provide pregnant women with a safe, accurate, and definitive assessment of fetal aneuploidy. This approach aims to alleviate the anxiety associated with traditional multi-step prenatal screening methods, which often have high false-positive rates and can yield confusing results. By offering a single blood draw test, Verinata seeks to fulfill the recommendations for first trimester aneuploidy risk assessment, thereby enhancing the overall experience for expectant mothers. The company is actively conducting a prospective, blinded pivotal study to validate the sensitivity and specificity of its first prenatal test on a large scale, with results anticipated in the near future.

GigaOm is a media company that specializes in providing news, analysis, and opinions on startups and emerging technologies. Founded in 2006 by Om Malik and based in San Francisco, GigaOm aims to humanize technology and offer deep insights into disruptive companies and trends. The company attracts over 6.5 million unique monthly readers who rely on its content to comprehend significant technological disruptions and the business opportunities that arise from them. GigaOm's information is produced by a network of more than 200 independent analysts, who deliver timely content bridging breaking news and long-term research. Additionally, GigaOm hosts events that combine focused editorial content with opportunities for attendees to engage with technology disruptors, equipping them with the tools needed to capitalize on emerging trends. The company serves both individual and corporate subscribers, making it a valuable resource for those seeking in-depth analysis of the technology landscape.

ForteBio is a life science company that specializes in developing analytical systems for the rapid and real-time quantification and characterization of proteins and their interactions. The company offers a range of instruments known as the Octet family, designed to provide scientists with detailed information about biomolecular interactions in micro-volume sample sizes. These systems facilitate the analysis of proteins, peptides, DNA, RNA, and small molecules in a microplate format. Among its key products are the Octet RED, which enables quantitation and kinetic analysis while supporting small molecule screening, as well as the Octet Q and QK models, which also focus on quantitation and kinetics. Through these advanced tools, ForteBio aims to enhance research capabilities in the field of biomolecular interactions.

Humanigen, Inc. is a clinical-stage biopharmaceutical company based in Burlingame, California, that specializes in the development of proprietary monoclonal antibodies aimed at immunotherapy and oncology treatments. The company’s leading candidate, Lenzilumab, targets granulocyte-macrophage colony-stimulating factor and is currently undergoing Phase Ib/II clinical trials for chronic myelomonocytic leukemia and juvenile myelomonocytic leukemia. Additionally, Humanigen is developing Ifabotuzumab, which targets the EphA3 receptor and has completed the Phase I portion of a Phase I/II clinical trial for various hematologic malignancies. The company is also working on HGEN005, an anti-EMR1 monoclonal antibody in the pre-clinical stage for eosinophilic diseases. Humanigen has established collaborations, including a clinical partnership with Kite Pharma to study Lenzilumab in patients with relapsed or refractory diffuse large B-cell lymphoma and a research agreement with the Department of Defense to facilitate the development of Lenzilumab for potential emergency use in COVID-19. Formed in 2000, the company was previously known as KaloBios Pharmaceuticals and rebranded as Humanigen in 2017.

KaloBios Pharmaceuticals provides medicines for respiratory diseases and certain cancers. The company is a biopharmaceutical company focused on advancing medicines for patients with neglected and rare diseases. They designed to overcome marketed antibody products.

3Leaf Systems specializes in server virtualization solutions that enhance corporate data center initiatives, focusing on power management and optimized scale-out architectures. Their Virtual Compute Environment (VCE) architecture provides system-level virtualization, allowing organizations to achieve mainframe-class capabilities on commodity servers. By utilizing 3Leaf's technology, businesses can significantly lower their infrastructure and operational costs while enabling rapid deployment and provisioning of data center resources. This ensures that organizations can meet the demands of modern applications effectively.

Hightail, Inc. is a cloud services company that specializes in file sharing and creative collaboration, enabling professionals to share large files such as videos, designs, artwork, and presentations. Founded in 2004 and based in Campbell, California, Hightail offers a platform that enhances visual project management by allowing users to preview files, comment, assign tasks, and manage versions visually. The company serves a diverse clientele, including agencies, creative and marketing departments, and businesses worldwide. Hightail also provides digital transformation services, focusing on data organization and content protection through various business processes. In 2013, Hightail rebranded from its original name, YouSendIt, and it operates as a subsidiary of Open Text Corporation.

Pacific Biosciences specializes in human, microbial, plant, and animal genomics, focusing on areas such as infectious disease research. The company designs and manufactures sequencing systems that address complex genetic challenges, utilizing its innovative single molecule real-time (SMRT) sequencing technology to detect biological processes in real time. Its product offerings include the PacBio RS II and Sequel Systems, which facilitate the monitoring and analysis of biochemical reactions at the single-molecule level, along with consumables like SMRT cells and various reagent kits. Customers range from research institutions and commercial laboratories to pharmaceutical and agricultural companies, with sales conducted through direct channels in North America and Europe, and distribution partners in Asia, the Middle East, and Latin America. Founded in 2000 and headquartered in Menlo Park, California, Pacific Biosciences continues to advance genomics research and applications.

Verinata Health is a company dedicated to improving maternal and fetal health through the development of non-invasive tests designed for the early identification of fetal chromosomal abnormalities. Utilizing proprietary technologies, Verinata focuses on analyzing cell-free DNA in maternal blood to provide pregnant women with a safe, accurate, and definitive assessment of fetal aneuploidy. This approach aims to alleviate the anxiety associated with traditional multi-step prenatal screening methods, which often have high false-positive rates and can yield confusing results. By offering a single blood draw test, Verinata seeks to fulfill the recommendations for first trimester aneuploidy risk assessment, thereby enhancing the overall experience for expectant mothers. The company is actively conducting a prospective, blinded pivotal study to validate the sensitivity and specificity of its first prenatal test on a large scale, with results anticipated in the near future.

Moxsie is an online retailer where shoppers can discover independent fashion - including clothing, footwear and accessories from new, up and coming designers.

Zannel makes the mobile industry's first Instant Media Network(TM), which allows people to instantly and visually communicate what's happening now across mobile and the web, including all major social networks. Zannel won a Webby for Best Mobile Social Network in 2008, serves million of unique visitors per month, has over 50 partnerships with leading operators, media companies, and brands. Founded by the team that built the first large-scale mobile media storefronts in the US, Zannel combines the best of mobile messaging, media sharing, and social networking into an intuitive, compelling user experience. Located in San Francisco, Zannel is backed by USVP, Alloy, and Palomar Ventures.

Molecular Imprints Inc. is a company based in Austin, Texas, that specializes in the manufacture of imprint and lithography systems designed for creating nanometer-scale surface relief structures. Founded in 2001 as a spin-off from the University of Texas, the company has developed a robust portfolio of over 100 patents related to imprint tools, materials, and process technologies. Its core technology, Jet and Flash Imprint Lithography, utilizes an advanced Drop Pattern Generation System to enable precise deposition of photoresist on substrates in extremely small quantities, facilitating the consistent nanoimprinting of features down to 10 nanometers. This innovative approach caters to various high-tech industries, including displays, life sciences, and light-emitting diodes, by providing cost-effective solutions for nanopatterning applications.

NovaSys Health is a prominent provider of managed healthcare services, operating one of the largest health plans in Arkansas. With approximately 11,000 contracted providers in the region and over 4,300 in Arkansas, the company emphasizes strong relationships with healthcare providers. It offers a range of health plans and related services, including customized solutions, provider relations, and eligibility and billing administration, catering to a diverse network of hospitals, physicians, and ancillary providers.

$25 million in Series C preferred stock financing. The financing will be used to ramp up operations and prepare for sales and marketing in anticipation of the company commercializing its first product, the Novasys Micro-remodeling™ System. The system, which is designed to treat female stress urinary incontinence (SUI), has received the CE Mark for use in the European Union and is pending FDA marketing clearance for sale in the United States. Novasys Medical Inc is testing a new, non-incisional, transurethral treatment which requires no visualization of the treatment site (neither cystoscopy nor fluoroscopy), being guided by familiar balloon palpation (similar to a Foley catheter). In addition, the Novasys Micro-remodeling™ System incorporates numerous, automatic safety features making the treatment process very easy to learn and use. The treatment does not require general anesthesia and is performed in the outpatient or office setting. Not only is the treatment rapid (less than 10 minutes), but patients immediately return to virtually all activities. As there are no incisions, no wound care or dressing changes are required.

Xactly is a prominent global provider of cloud-based Sales Performance Management solutions designed to enhance the effectiveness of sales organizations. The company specializes in planning and managing sales quotas, territories, and incentive compensation, while also offering predictive analytics to inform strategic decision-making. Its software platform enables employers to design and automate compensation plans that align employee incentives with business objectives. By delivering error-free commission payments and on-demand visibility, Xactly fosters employee trust and loyalty, thereby improving operational efficiencies and productivity. The company's solutions aim to optimize sales behaviors, enhance employee performance, and mitigate risks, ultimately supporting organizations in achieving their business goals.

OptiMedica Corporation is a Silicon Valley-based ophthalmic device company established in 2004, focused on advancing technologies to enhance patient outcomes in eye care. The company specializes in developing a noninvasive, reproducible technique that utilizes femtosecond laser technology to improve the precision and consistency of cataract surgery, addressing the limitations of traditional manual methods. OptiMedica's flagship product, the Catalys Precision Laser System, has undergone successful clinical trials, demonstrating significant improvements in performance and efficacy for cataract surgeons and their patients. Although the system is not yet available for sale in the United States, OptiMedica aims to launch it in both U.S. and international markets.

Labcyte Inc., founded in 2000 and based in San Jose, California, specializes in developing acoustic droplet ejection (ADE) technology for various applications in the life sciences. The company's innovative approach uses focused beams of acoustic energy to precisely dispense nanoliter-scale droplets of fluid from one plate to another, enabling high accuracy at low volumes and reducing consumables costs. Labcyte's products include automation systems, laboratory workstations, and control software, which are utilized in drug discovery, genomics research, cancer research, and personalized medicine. The company operates as a subsidiary of Beckman Coulter, Inc., with additional offices across multiple countries including Canada, the United Kingdom, Australia, India, South Korea, China, Hong Kong, Japan, Singapore, and Taiwan.

Ciranova, Inc. is an electronic design automation company headquartered in Santa Clara, California, established in 2002. The company specializes in developing interoperable tools for custom chip designers, enabling the creation and migration of legacy analog intellectual property (IP). Ciranova offers products such as PyCell Studio, which streamlines the processes of PCell and layout generator creation for deep submicron technologies, and PCell Xtreme, which facilitates the transition of PCells written in proprietary languages to multi-vendor OpenAccess environments. In addition to its software solutions, Ciranova provides a range of consulting services, including custom layout generator development, Python code development, layout consulting, and analog and mixed-signal design services, helping engineers integrate complex RF and analog content into high-density, high-speed nanometer-scale silicon.

Retrevo is a specialized shopping site dedicated to consumer electronics, offering a platform for product search, discovery, recommendations, and purchase. It has emerged as one of the largest online resources for consumer electronics shopping and reviews. Utilizing machine learning and Big Data Analytics, Retrevo analyzes extensive private and public unstructured data to provide consumers with comprehensive, current, and objective product insights. The website aggregates information from experts, user reviews, PDF manuals, and various web sources, enabling users to access detailed summaries and answers about a wide range of electronic products, including camcorders, GPS devices, laptops, digital cameras, and home theater systems. Through this approach, Retrevo aims to enhance the consumer experience by simplifying the decision-making process in the electronics market.

AEGEA Medical, Inc. is a medical technology company based in Menlo Park, California, that specializes in innovative treatments for women's health. The company has developed a water vapor ablation system, known as Mara, which is designed for the in-office treatment of heavy menstrual bleeding, specifically menorrhagia. This FDA-approved technology utilizes adaptive vapor ablation to deliver safe and effective endometrial ablation in a simple procedure that takes only minutes. AEGEA Medical aims to expand treatment options for a broader range of patients while ensuring convenience and confidence for physicians performing these office-based procedures. The company was incorporated in 2007 and continues to focus on enhancing patient outcomes in women's healthcare.

LightPole is designed to give you information you're interested in about points of interest (POI)—locations such as your current location or locations you're traveling to. For any location, LightPole is designed to answer the most probable questions in the shortest amount of time and with the least amount of interaction.

ViVOtech, Inc. is a provider of software and hardware solutions focused on the Near Field Communication (NFC) mobile payment and promotion market. Founded in 2001, the company specializes in contactless payment systems, including NFC smart posters and infrastructure software for over-the-air (OTA) card provisioning, promotions, and transaction management. Its offerings encompass the ViVOnfc software for mobile payments and promotions, as well as the ViVOplatform, which assists retailers with promotional and loyalty applications. ViVOtech's technology is integrated into various sectors, including movie theaters, fast food restaurants, convenience stores, gas stations, and public transportation, catering to merchants, issuing banks, and wireless operators. In October 2012, Sequent Software, Inc. acquired ViVOtech’s software division, enabling further development in the NFC space.

Ravenflow is a provider of business requirements definition software designed to help enterprises accelerate application delivery. The company's flagship product, RAVEN, facilitates requirements elicitation and definition, enabling stakeholders to reach consensus more quickly and reducing the time needed for approval of specifications. By minimizing developer rework due to requirements errors and integrating requirements with testing processes, Ravenflow enhances overall efficiency. The software also assists business analysts in visualizing and validating requirements, producing specifications for business process workflows, use cases, and application needs. In addition to its software offerings, Ravenflow provides training and professional services, serving a diverse range of sectors including finance, banking, insurance, government, telecommunications, technology, healthcare, and education, as well as independent software vendors and systems integrators.

Ensenda is a prominent third-party logistics provider specializing in local delivery services across North America. The company offers a comprehensive range of logistics solutions for various sectors, including home and commercial delivery, catering to industries such as furniture retail, industrial supply, printing, office supplies, electronics, and logistics. With a robust network of local carriers, Ensenda ensures efficient and timely delivery, addressing the critical last-mile challenges that significantly impact customer satisfaction and loyalty. By focusing on enhancing the delivery experience, Ensenda plays a vital role in optimizing supply chain operations for its clients.

Arbor Surgical Technologies, Inc. located in Irvine and Portola Valley, CA (USA), is a privately held cardiovascular medical device company focused on the heart valve replacement market. Founded in 2002 by Dr. Thomas J. Fogarty and noted heart valve designer, Ernie Lane, Arbor is developing multiple technologies that have the potential to deliver significant clinical benefit to patients worldwide. Arbor intends to develop and commercialize its core technologies in varying combinations, giving the company the opportunity to create a portfolio of product offerings. Currently in clinical trials, Arbor is developing a tissue heart valve family of products designed for improved performance over existing valves and compatible implantation tools that simplify and speed valve replacement surgery.

Zest Labs specializes in real-time data visibility solutions for cold chain management and asset tracking. They offer industry-leading XC3 RFID products and technologies that enable temperature monitoring for perishable foods and pharmaceuticals, asset tracking at remote worksites, vehicle/yard management, security access control, and other applications. These solutions help businesses reduce waste, improve operational efficiency, lower costs, and enhance profitability.

Qwaq was renamed to Teleplace and is now 3D Immersive Collaboration Consulting. See www.3dicc.com. Qwaq is a company building enterprise applications that use 3D virtual environments for realtime collaboration and conferencing. Qwaq's flagship product, Qwaq forums, includes built-in voice communication and text chat, as well as the ability for users to share existing applications. The underlying system is built on top of Croquet, an open source 3D space system manager. Users begin as they enter a virtual room, occupied by other users and objects like tables and posters on the walls. Many of those objects are standard desktop items -- a poster on the wall, for example, might be a Word document or Excel spreadsheet. When users click on the poster from "across" the room, or access it via keyboard shortcut, it expands to fill up their screen. In addition to chatting with the other users, users can add or subtract objects, or move through different rooms as desired. Qwaq Forums is designed for business computers, which tend to be less powerful than home computers. France based [Tixeo](http://www.tixeo.com/), is another start-up focused on the same market. A slew of other companies offering tools to set up and collaborate in virtual worlds include [Second Life](http://www.crunchbase.com/organization/secondlife), [VastPark](http://www.vastpark.com/), [ProtonMedia](http://www.protonmedia.com/), [Forterra Systems](http://www.forterrainc.com/), and [Multiverse](http://www.crunchbase.com/organization/Multiverse).

AnaptysBio, Inc. is a clinical-stage biotechnology company based in San Diego, California, dedicated to developing therapeutic antibodies for inflammation and immuno-oncology. The company employs its proprietary somatic hypermutation platform to discover and optimize antibodies that target various diseases. Among its notable product candidates are Etokimab, an anti-IL-33 treatment aimed at conditions such as atopic dermatitis and eosinophilic asthma, and ANB019, an anti-IL-36 receptor for generalized pustular psoriasis. AnaptysBio is also advancing a range of immuno-oncology products, including checkpoint modulators and bispecific antibodies, to address cancer treatment needs. The company collaborates with notable partners like TESARO, Celgene Corporation, and GlaxoSmithKline to enhance its research and development efforts. Founded in 2005, AnaptysBio aims to fulfill unmet medical needs through innovative antibody therapies.

Xangati, Inc. is a company that specializes in IT operations analytics and performance control for virtualized, private, and hybrid-cloud environments. Founded in 2003 and headquartered in San Jose, California, Xangati offers a suite of software solutions that enable organizations to monitor performance metrics at an unprecedented level of granularity. Its platforms provide deep analytics that facilitate performance problem tracking, prevention, and remediation, allowing for predictive insights into end-user experiences. By correlating application-level metrics across virtual servers, desktops, and applications, Xangati delivers real-time visibility and service assurance analytics that enhance infrastructure health. The company supports a diverse clientele, including enterprises, government agencies, healthcare organizations, academic institutions, and cloud service providers. Xangati's innovative management dashboards are built on patented in-memory architecture, providing continuous interaction and actionable insights into IT operations.

Restoration Robotics is a privately held medical device company focused on advancing hair transplantation technology. It has developed the ARTAS™ System, an innovative image-guided platform that facilitates follicular unit extraction, enhancing the precision and efficiency of hair restoration procedures. By integrating advanced imaging and robotics, Restoration Robotics aims to improve outcomes for patients seeking hair transplants, positioning itself as a leader in the evolving field of hair restoration. The company is committed to transforming traditional practices through its state-of-the-art technology.

KFx Medical specializes in the development and manufacturing of advanced soft tissue fixation implants specifically designed for orthopedic sports medicine. The company creates innovative products that facilitate tissue fixation, allowing for direct placement into bone, with or without sutures. These implants are utilized in various orthopedic surgical procedures, enabling surgeons to effectively reattach tissue in areas such as the shoulder, knee, foot, and ankle. KFx Medical collaborates with leading orthopedic surgeons to refine its technology and enhance surgical outcomes for patients.

ViVOtech, Inc. is a provider of software and hardware solutions focused on the Near Field Communication (NFC) mobile payment and promotion market. Founded in 2001, the company specializes in contactless payment systems, including NFC smart posters and infrastructure software for over-the-air (OTA) card provisioning, promotions, and transaction management. Its offerings encompass the ViVOnfc software for mobile payments and promotions, as well as the ViVOplatform, which assists retailers with promotional and loyalty applications. ViVOtech's technology is integrated into various sectors, including movie theaters, fast food restaurants, convenience stores, gas stations, and public transportation, catering to merchants, issuing banks, and wireless operators. In October 2012, Sequent Software, Inc. acquired ViVOtech’s software division, enabling further development in the NFC space.

Adzilla operates a technology platform that enables internet service providers (ISPs) to deliver targeted advertising based on action-based behavioral and demographic information to publisher sites and advertising networks.

Apptera is a mobile communications and advertising company that specializes in delivering multimedia content and interactive experiences to mobile devices. Its flagship product, Raved, enhances consumer engagement while the Apptera MobileAd Network connects advertisers with a diverse array of publishers, enabling effective outreach to millions of mobile users. The company collaborates with notable partners such as AOL Moviefone and Movietickets.com to maximize advertising impact. Founded in 2001 and based in Silicon Valley, Apptera has received several industry accolades, including recognition as one of the OnMobile 100 Top Private Companies in 2011. The company also holds multiple patents related to its communications technology, underscoring its innovative approach in the mobile advertising space. Apptera maintains additional offices in New York and Los Angeles, reflecting its expansive operational footprint.

3Leaf Systems specializes in server virtualization solutions that enhance corporate data center initiatives, focusing on power management and optimized scale-out architectures. Their Virtual Compute Environment (VCE) architecture provides system-level virtualization, allowing organizations to achieve mainframe-class capabilities on commodity servers. By utilizing 3Leaf's technology, businesses can significantly lower their infrastructure and operational costs while enabling rapid deployment and provisioning of data center resources. This ensures that organizations can meet the demands of modern applications effectively.

Hightail, Inc. is a cloud services company that specializes in file sharing and creative collaboration, enabling professionals to share large files such as videos, designs, artwork, and presentations. Founded in 2004 and based in Campbell, California, Hightail offers a platform that enhances visual project management by allowing users to preview files, comment, assign tasks, and manage versions visually. The company serves a diverse clientele, including agencies, creative and marketing departments, and businesses worldwide. Hightail also provides digital transformation services, focusing on data organization and content protection through various business processes. In 2013, Hightail rebranded from its original name, YouSendIt, and it operates as a subsidiary of Open Text Corporation.

Xactly is a prominent global provider of cloud-based Sales Performance Management solutions designed to enhance the effectiveness of sales organizations. The company specializes in planning and managing sales quotas, territories, and incentive compensation, while also offering predictive analytics to inform strategic decision-making. Its software platform enables employers to design and automate compensation plans that align employee incentives with business objectives. By delivering error-free commission payments and on-demand visibility, Xactly fosters employee trust and loyalty, thereby improving operational efficiencies and productivity. The company's solutions aim to optimize sales behaviors, enhance employee performance, and mitigate risks, ultimately supporting organizations in achieving their business goals.

Mavenir is a cloud-native network software provider that focuses on transforming telecommunications networks for Communications Service Providers (CSPs). The company offers a comprehensive suite of products that spans all layers of network infrastructure, including 5G application layers, packet core, and radio access networks (RAN). With a track record of pioneering advanced technologies such as VoLTE and Virtualized RAN, Mavenir serves over 250 CSP customers in more than 130 countries, impacting over 50% of global subscribers. Their innovative solutions are designed to enhance service agility and reduce costs while promoting revenue generation and protection. By leveraging disruptive technology architectures, Mavenir aims to redefine network economics and accelerate the evolution of network functions virtualization (NFV) to achieve web-scale efficiencies.

Cambridge Heart, Inc. is a company focused on the research, development, and commercialization of non-invasive diagnostic products for cardiac disease. Based in Tewksbury, Massachusetts, it offers several key products, including the Heartwave II System for performing Microvolt T-Wave Alternans (MTWA) tests, Micro-V Alternans Sensors designed for single-use in MTWA testing, and the CH2000 Cardiac Stress Test System, which supports a variety of cardiac exercise stress testing protocols. Cambridge Heart primarily sells its products to cardiology group practices, hospitals, and research institutions, and it markets its offerings internationally through independent distributors. Established in 1990, the company continues to play a significant role in advancing cardiac diagnostic technology.

Cambrios Technologies Corporation is a manufacturer of innovative electronic materials specializing in silver nanowire-based electrodes. Founded in 2002 and originally named Semzyme, Inc., the company rebranded in August 2004. Headquartered in Sunnyvale, California, with additional offices in Japan and Taiwan, Cambrios develops products such as ClearOhm, which are transparent conductive coatings that can be applied to various substrates for multiple applications. These include touch screens, liquid crystal displays, e-paper, OLED devices, and lighting, as well as thin film photovoltaics like organic photovoltaics and printed organic solar cells. Cambrios's technology enables simplified manufacturing processes and enhances the performance of next-generation consumer devices.

Teradici Corporation specializes in PC-over-IP (PCoIP) technology, which transfers the image of software from central servers or workstations to various end-points, facilitating local, remote, mobile, and collaborative work styles. The company offers a range of PCoIP solutions, including zero clients, optimized thin clients, hardware accelerators, remote workstation cards, workstation access software, and a management console for streamlined deployment and management of PCoIP devices. Teradici's offerings extend to cloud solutions such as desktop virtualization infrastructure and Desktop as a Service, as well as optimization and monitoring tools. The company's clientele includes Fortune 500 enterprises, educational institutions, government agencies, and service providers across various sectors, including healthcare, media, manufacturing, and construction. Founded in 2004 and based in Burnaby, Canada, Teradici has developed a strong ecosystem of products and services and maintains strategic partnerships with companies like Dell Wyse and Socionext Inc. Its commitment to innovation is underscored by its significant investment in research and development, resulting in over 40 patents.

Pacific Biosciences specializes in human, microbial, plant, and animal genomics, focusing on areas such as infectious disease research. The company designs and manufactures sequencing systems that address complex genetic challenges, utilizing its innovative single molecule real-time (SMRT) sequencing technology to detect biological processes in real time. Its product offerings include the PacBio RS II and Sequel Systems, which facilitate the monitoring and analysis of biochemical reactions at the single-molecule level, along with consumables like SMRT cells and various reagent kits. Customers range from research institutions and commercial laboratories to pharmaceutical and agricultural companies, with sales conducted through direct channels in North America and Europe, and distribution partners in Asia, the Middle East, and Latin America. Founded in 2000 and headquartered in Menlo Park, California, Pacific Biosciences continues to advance genomics research and applications.

Fluidigm Corporation develops and markets innovative technologies and tools for life sciences research globally. The company specializes in integrated fluidic circuits that control fluids at the nanoscale, enabling a range of applications in biological research. Its product offerings include analytical systems such as the Helios CyTOF system, the Hyperion imaging system, and the Biomark HD system, along with various assays and reagents designed for immuno-oncology and genetic analysis. Fluidigm also provides preparatory instruments and single-cell microfluidics, such as the C1 and Polaris systems. The company serves a diverse clientele, including academic institutions, clinical research laboratories, biopharmaceutical, biotechnology, and agricultural biotechnology companies, focusing on non-diagnostic and non-clinical applications. Established in 1999 as Mycometrix Corporation, it adopted the name Fluidigm Corporation in 2001 and is headquartered in South San Francisco, California.

Codon Devices is a biotechnology company, engages in developing, constructing, and delivering synthetic biology products for research. The company focuses on discovering and manufacturing synthetic biological parts. Its BioLOGIC Engineering Platform combines sophisticated design algorithms with assay and protein engineering capabilities to result in a system for the design, discovery, and optimization of proteins for specific applications; and BioFAB Production Platform, which produces synthetic genes.

MontaVista Software specializes in the commercialization of embedded Linux, providing businesses with high-quality Linux solutions and developer tools tailored for the embedded device market. The company offers Market Specific Distributions (MSDs) that support various applications, including industrial automation, automotive systems, Android devices, portable multimedia, and multicore networking. MontaVista's products are designed to streamline the development process, significantly reducing the time and effort required to bring commercial products to market. With expert support and hardware enablement, MontaVista enhances the capabilities of open-source Linux, contributing to the deployment of over 50 million devices globally that rely on their Linux offerings.

Retrevo is a specialized shopping site dedicated to consumer electronics, offering a platform for product search, discovery, recommendations, and purchase. It has emerged as one of the largest online resources for consumer electronics shopping and reviews. Utilizing machine learning and Big Data Analytics, Retrevo analyzes extensive private and public unstructured data to provide consumers with comprehensive, current, and objective product insights. The website aggregates information from experts, user reviews, PDF manuals, and various web sources, enabling users to access detailed summaries and answers about a wide range of electronic products, including camcorders, GPS devices, laptops, digital cameras, and home theater systems. Through this approach, Retrevo aims to enhance the consumer experience by simplifying the decision-making process in the electronics market.

Hightail, Inc. is a cloud services company that specializes in file sharing and creative collaboration, enabling professionals to share large files such as videos, designs, artwork, and presentations. Founded in 2004 and based in Campbell, California, Hightail offers a platform that enhances visual project management by allowing users to preview files, comment, assign tasks, and manage versions visually. The company serves a diverse clientele, including agencies, creative and marketing departments, and businesses worldwide. Hightail also provides digital transformation services, focusing on data organization and content protection through various business processes. In 2013, Hightail rebranded from its original name, YouSendIt, and it operates as a subsidiary of Open Text Corporation.

Polimetrix engages in survey research and analytics for research needs. The company provides BrandIndex, an information product that collects responses and calculates BIX net metrics based on the responses. It offers consulting, online survey, and online qualitative services. Polimetrix conducts surveys and polls for democratic, republican, and independent consultants; market research agencies; corporate public affairs groups; media organizations; university researchers; and non-profit organizations through its Website. The company was founded in 2004 and is headquartered in Palo Alto, California. Polimetrix, Inc. operates as a subsidiary of YouGov PLC.

Attune Systems, Inc. specializes in network file management solutions aimed at simplifying file management for enterprise, government, and educational sectors. The company offers the Maestro File Manager, a file virtualization appliance designed to assist IT administrators in discovering, analyzing, managing, and optimizing heterogeneous file storage resources. In addition to file management, Attune Systems provides services such as archive intelligence, security diligence, data migration and consolidation, disaster recovery, forensic search, and tiered backup and storage with deduplication. Founded in 1999 and headquartered in Santa Clara, California, the company has established strategic partnerships with prominent technology firms including Microsoft, Data Domain, NetApp, Symantec, and Google. However, it has recently experienced significant changes and has become less prominent in the industry.