Alumni Ventures

Epicore Biosystems, Inc. is a Cambridge, Massachusetts-based company founded in 2017 that specializes in developing and commercializing a wearable microfluidic sensing platform. This innovative technology analyzes small droplets of sweat directly from the skin to provide insights into health, hydration, and athletic performance. The platform is designed to measure various biomarkers, including proteomics and inflammatory markers, allowing for personalized management of health and nutrition. Epicore's approach leverages over two decades of research in microfluidics and soft materials conducted by leading experts at Northwestern University. By offering a non-invasive and cost-effective solution, Epicore aims to enhance athletic performance and improve overall health monitoring for users.

Precision Neuroscience is a company focused on developing advanced brain-computer interface technology aimed at offering innovative treatments for the approximately one billion individuals worldwide affected by neurological disorders. Founded in 2021 and based in New York, the company's technology is characterized by its minimally invasive design, safety for removal, and capacity for processing substantial data. This platform enables medical professionals to establish a direct connection between the human brain and artificial intelligence, potentially transforming the landscape of neurological care.

Lōvu Health is a digital health company specializing in maternal care. It provides a platform that supports mothers and babies from conception through to postpartum, using AI to deliver real-time analytics and evidence-based insights. The platform monitors vital signs like fetal heart rate and blood pressure, offers personalized recommendations, and sends action-oriented alerts, empowering users with reliable information and expert knowledge.

Andromeda Surgical is a developer of autonomous robots designed to enhance the consistency, accuracy, and efficiency of surgical procedures. The company's open platform focuses on urologic procedures that have demonstrated superior outcomes but face challenges in widespread adoption due to technical complexities. By addressing these difficulties, Andromeda Surgical aims to empower surgeons to perform various procedures at a level typically achieved only by experts, thereby improving patient care and surgical success rates.

CytoVale, Inc. is a medical technology company based in San Francisco, California, established in 2012. The company specializes in developing biomarkers that leverage the mechanical properties of individual cells, a field known as mechanomics. By utilizing microfluidics technology, CytoVale can efficiently route and physically probe single cells to measure multiple biomarkers simultaneously. This innovative approach aims to enhance early detection of immune-mediated diseases, particularly sepsis, thereby improving patient outcomes and reducing treatment costs. CytoVale's integration of cell mechanics with machine learning positions it at the forefront of revolutionizing diagnostic practices in healthcare.

Centaur Labs specializes in medical data annotation services, aimed at enhancing medical decision-making and diagnostics. The company utilizes a platform that connects a global network of students and professionals, who compete to provide high-quality data labeling. This collaborative model ensures exceptional accuracy and scalability in annotating medical and scientific data. By analyzing medical cases and labeling data effectively, Centaur Labs contributes to the development of advanced medical AI technologies, ultimately helping patients achieve better healthcare outcomes while potentially reducing costs.

Magnetic Insight, Inc. specializes in magnetic particle imaging (MPI), an innovative imaging technology that utilizes iron oxide nanoparticle tracers and time-varying magnetic fields. The company has developed several products, including the MOMENTUM imager, a pre-clinical MPI solution that produces high-quality images through advanced magnet geometry and a proprietary reconstruction process. Additionally, Magnetic Insight offers VivoTrax, a nanoparticle designed for cell tracking and as a blood pool agent in pre-clinical studies, and Hyper, an add-on module for the MOMENTUM system that assists in identifying treatment targets and administering localized magnetic hyperthermia. Another product, Relax, serves as a particle relaxometry module. Founded in 2012 and headquartered in Alameda, California, Magnetic Insight aims to enhance preclinical diagnostic research by enabling quantitative cell tracking, imaging of vascular functions, and visualization of various biological processes, thereby addressing challenges in clinical and translational research.

Nanochon is focused on creating innovative implantable medical devices designed to address cartilage damage in joints. Utilizing advanced 3D printing techniques and a unique nanomaterial, the company aims to develop solutions that not only replace lost and damaged cartilage but also promote the growth of new tissue. This approach allows medical practitioners to access cost-effective and on-demand devices that enhance treatment outcomes, particularly for young and active patients suffering from knee injuries and diseases. Through its technology, Nanochon seeks to improve the overall quality of care in orthopedics.

Pi Health is a technology company specializing in streamlining oncology clinical trials. It offers a global, secure, and compliant platform that integrates various systems, enabling life sciences companies to identify suitable trial sites, manage them efficiently, and accelerate the development of lifesaving medicines. This, in turn, enhances patient access to cancer care and research, particularly for diverse populations.

Epicore Biosystems, Inc. is a Cambridge, Massachusetts-based company founded in 2017 that specializes in developing and commercializing a wearable microfluidic sensing platform. This innovative technology analyzes small droplets of sweat directly from the skin to provide insights into health, hydration, and athletic performance. The platform is designed to measure various biomarkers, including proteomics and inflammatory markers, allowing for personalized management of health and nutrition. Epicore's approach leverages over two decades of research in microfluidics and soft materials conducted by leading experts at Northwestern University. By offering a non-invasive and cost-effective solution, Epicore aims to enhance athletic performance and improve overall health monitoring for users.

Earli is a company focused on developing innovative cancer treatment devices that utilize synthetic biomarkers for early cancer detection. The company's approach involves a novel gene therapy technique known as Synthetic Biopsy, which prompts cancer cells to produce synthetic, non-human biomarkers. These biomarkers can be detected through various means, including blood, urine, or breath, allowing for timely tracking and treatment of cancer. By facilitating the early identification of cancer when it is still homogeneous, Earli aims to significantly enhance survival rates. Their technology not only aids in detection but is also applicable for therapeutic interventions, thereby personalizing treatment and improving patient outcomes.

CytoVale, Inc. is a medical technology company based in San Francisco, California, established in 2012. The company specializes in developing biomarkers that leverage the mechanical properties of individual cells, a field known as mechanomics. By utilizing microfluidics technology, CytoVale can efficiently route and physically probe single cells to measure multiple biomarkers simultaneously. This innovative approach aims to enhance early detection of immune-mediated diseases, particularly sepsis, thereby improving patient outcomes and reducing treatment costs. CytoVale's integration of cell mechanics with machine learning positions it at the forefront of revolutionizing diagnostic practices in healthcare.

Emm is focused on creating innovative consumer health tools that empower individuals to manage their health effectively. The company has developed a wearable device aimed at enhancing reproductive health by providing users with biometric data that offers actionable insights into their unique reproductive profiles. This technology enables users and their healthcare providers to identify potential health issues and optimize reproductive health outcomes, thereby improving the overall quality of life. Emm's approach combines advanced technology with specialized knowledge to enhance personal health management.

Basil Systems operates a software-as-a-service platform that utilizes machine learning to analyze product, market, and regulatory data specifically for the medical device and pharmaceutical sectors. The platform offers critical analytics and insights that support strategic decision-making in product development, enhance product and supply chain quality, and minimize the risks associated with product recalls. Additionally, it aims to reduce the time required for regulatory approvals, ultimately enabling companies to deliver safe and effective products to consumers.

TFC Therapeutics is a biotechnology company focused on developing innovative biologics aimed at addressing key drivers of cancer recurrence and metastasis. The company’s technology utilizes monoclonal antibodies that specifically bind to receptors on the surface of tumor-initiating cells (TMH cells). This binding action activates the immune system to target and destroy these cells, offering the potential for new cancer treatments. By concentrating on the elimination of TMH cells, TFC Therapeutics seeks to provide effective solutions for improving patient outcomes in cancer care.

VenoStent, Inc. is a clinical-stage tissue engineering company based in Nashville, Tennessee, with an additional office in Houston, Texas. Founded in 2017, it specializes in the development of bioresorbable smart polymers designed to enhance vascular surgery outcomes. The company’s primary product, SelfWrap, is a perivascular wrap that functions as an external stent, providing mechanical support to veins and promoting outward growth. This innovative technology aims to reduce complications at the vein-artery junction in dialysis patients, particularly by minimizing vein collapse and improving the usability of arteriovenous fistulas (AVF). By utilizing a new class of shape-memory polymers that do not require sutures, VenoStent's approach reduces surgery time and lowers the risk of infection, ultimately enhancing the quality and length of life for patients with chronic kidney disease undergoing hemodialysis.

Ossium Health, Inc. is engaged in the development and manufacturing of cell therapy products aimed at treating leukemia, other blood cancers, and tissue damage, as well as addressing radiation poisoning. The company offers a range of innovative therapies, including HPC, Marrow, which features HLA-matched bone marrow stem cells for hematopoietic reconstitution in blood cancer patients; Chimera, which enhances organ transplantation; and Chymalis, composed of mesenchymal stem cells that promote the healing of damaged bone and muscle tissue. Additionally, Ossium provides bone marrow cells for research purposes in oncology and immunology. Founded in 2016 and headquartered in San Francisco, California, Ossium Health focuses on improving health outcomes and longevity through advanced bioengineering techniques.

Upside Health, Inc. is a healthcare technology company based in New York, founded in 2017, that focuses on chronic pain management through its mobile application, Ouchie. This application provides targeted educational content and rewards for achieving functional milestones, fostering a support system for patients. Upside Health's platform includes remote patient monitoring and engagement tools that enable clinicians to enhance care quality while minimizing the burden on healthcare providers. By empowering patients with data and social support, Upside Health aims to improve outcomes for chronic pain sufferers and create revenue-generating opportunities for healthcare practices.

MedScout is a revenue acceleration platform tailored for medical device and diagnostic companies. It offers sales enablement software that integrates medical claims intelligence from both public and private payors, providing users with critical insights into market dynamics. The platform is designed to assist sales professionals and leaders by delivering data on patient demographics, procedure volumes, referral patterns, and payment information. This functionality allows clients to conduct thorough market analysis, develop effective strategies, and enhance sales execution, ultimately optimizing operational productivity and fostering growth in their respective territories.

Ascent Integrated Tech develops a hardware-enabled software platform focused on enhancing situational awareness for first responders and military personnel. Its Tactical Assault Kit (TAK) integrates with smartwatches and existing equipment to provide real-time location tracking and physiological alerting, significantly improving safety and operational decision-making during emergencies. The platform offers comprehensive monitoring and mapping capabilities in hazardous environments, enabling incident commanders to assess the status of their teams and make informed evacuation decisions through a biometric tracking system. Ascent’s technology is utilized by major metropolitan fire departments across the United States and is expanding internationally through strategic partnerships. The company is supported by government contracts and venture funding, positioning itself as a leader in redefining emergency response effectiveness.

MEND is a life sciences company dedicated to advancing health and recovery through targeted clinical nutrition and medical food interventions. The company focuses on researching and developing products that enhance patient outcomes in various contexts, including injury recovery, surgical recovery, aging, and physical performance. MEND's solutions have been widely adopted by hospitals, health systems, and professional sports teams across major leagues, as well as by the elite forces of the US Military. Through its commitment to ongoing research and development, MEND aims to empower caregivers and improve health outcomes for individuals facing diverse health challenges.

Iolyx Therapeutics is a biotechnology company focused on developing solutions for ocular diseases. Operating at the intersection of immunology and ophthalmology, the company aims to transform the standard of care for these conditions. Iolyx Therapeutics utilizes an innovative platform that provides tailored formulations for precise delivery to targeted eye tissues. Its products are designed to address ocular inflammation directly at its source, affecting both the front and back of the eye. This approach seeks to enhance efficacy, safety, and convenience for patients suffering from various ocular conditions.

Rensair specializes in the development of portable hospital-grade air purifiers that aim to provide clean air in various environments. Initially designed for Scandinavian hospitals, their air purification technology incorporates high-efficiency particulate air (HEPA13) filters and ozone-free ultraviolet light, which effectively eliminates airborne viruses, including the coronavirus. Rensair's products are utilized in a range of settings, including hospitals, schools, and care homes, ensuring optimum indoor air quality and promoting health and safety in populated spaces. Trusted by businesses globally, Rensair's solutions are designed to enhance the well-being of individuals by improving the air quality they breathe.

Andromeda Surgical is a developer of autonomous robots designed to enhance the consistency, accuracy, and efficiency of surgical procedures. The company's open platform focuses on urologic procedures that have demonstrated superior outcomes but face challenges in widespread adoption due to technical complexities. By addressing these difficulties, Andromeda Surgical aims to empower surgeons to perform various procedures at a level typically achieved only by experts, thereby improving patient care and surgical success rates.

Mign specializes in developing personalized medical devices for musculoskeletal health, focusing on digitally tailored orthopedic products. The company employs proprietary technology that transforms complex three-dimensional body data into customized wearable items. These products feature breathable three-dimensional patterns designed to meet individual physical needs, effectively addressing various orthopedic issues. Mign aims to revolutionize the design, engineering, manufacturing, and delivery processes of medical devices, contributing to a more digital and sustainable future in healthcare.

Precision Neuroscience is a company focused on developing advanced brain-computer interface technology aimed at offering innovative treatments for the approximately one billion individuals worldwide affected by neurological disorders. Founded in 2021 and based in New York, the company's technology is characterized by its minimally invasive design, safety for removal, and capacity for processing substantial data. This platform enables medical professionals to establish a direct connection between the human brain and artificial intelligence, potentially transforming the landscape of neurological care.

MedCrypt Inc. is a cybersecurity company specializing in the protection of medical devices. Founded in 2016 and based in Encinitas, California, MedCrypt provides data security solutions for a wide range of medical devices, including implantable devices like pacemakers and various surgical robots. The company's platform offers data security as a service to medical device original equipment manufacturers (OEMs), enabling them to implement essential security features quickly and efficiently. These features include user authentication, data encryption, and transaction monitoring to detect potential malicious behavior. By integrating security capabilities into medical devices with minimal code, MedCrypt allows engineers to focus on developing innovative clinical functionalities while ensuring the safety and integrity of device operations.

Willow Inc., established in 2014 and headquartered in Mountain View, California, specializes in the manufacture of wearable breast pumps for women. The company offers a range of products including milk bags, accessories such as flanges and tubes, and replacement parts. Willow's flagship product is an in-bra wearable breast pump designed to provide mothers with mobility and hands-free convenience during breastfeeding. The company also provides pumping bras, cases, and other breastfeeding essentials.

Magnetic Insight, Inc. specializes in magnetic particle imaging (MPI), an innovative imaging technology that utilizes iron oxide nanoparticle tracers and time-varying magnetic fields. The company has developed several products, including the MOMENTUM imager, a pre-clinical MPI solution that produces high-quality images through advanced magnet geometry and a proprietary reconstruction process. Additionally, Magnetic Insight offers VivoTrax, a nanoparticle designed for cell tracking and as a blood pool agent in pre-clinical studies, and Hyper, an add-on module for the MOMENTUM system that assists in identifying treatment targets and administering localized magnetic hyperthermia. Another product, Relax, serves as a particle relaxometry module. Founded in 2012 and headquartered in Alameda, California, Magnetic Insight aims to enhance preclinical diagnostic research by enabling quantitative cell tracking, imaging of vascular functions, and visualization of various biological processes, thereby addressing challenges in clinical and translational research.

Miga is a virtual cardiometabolic clinic that focuses on improving heart health through an innovative platform that combines gamified mobile applications with comprehensive clinical services. Founded by Jarrad Aguirre, MD, and Dre Limberopoulos, Miga's offerings include at-home monitoring for blood pressure, telemedicine consultations, mail-order pharmacy services, and lifestyle coaching. The clinic addresses various cardiometabolic conditions such as obesity, hypertension, diabetes, and hyperlipidemia, empowering patients to manage their health effectively and reduce the risk of serious heart issues, including premature heart attacks and strokes.

Rensair specializes in the development of portable hospital-grade air purifiers that aim to provide clean air in various environments. Initially designed for Scandinavian hospitals, their air purification technology incorporates high-efficiency particulate air (HEPA13) filters and ozone-free ultraviolet light, which effectively eliminates airborne viruses, including the coronavirus. Rensair's products are utilized in a range of settings, including hospitals, schools, and care homes, ensuring optimum indoor air quality and promoting health and safety in populated spaces. Trusted by businesses globally, Rensair's solutions are designed to enhance the well-being of individuals by improving the air quality they breathe.

Activ Surgical Inc. is a digital surgery company based in Boston, Massachusetts, focused on enhancing surgical efficiency, accuracy, and patient outcomes through advanced technology. Founded in 2014, the company has developed a robotic surgery platform that integrates computer vision, artificial intelligence, and robotics to assist surgeons during complex procedures. One of its key products is the Smart Tissue Autonomous Robot (STAR), which aims to revolutionize surgical practices by improving intraoperative decision-making and reducing the risk of unintended surgical complications. The platform is scalable and patent-protected, designed to support surgeons with augmented reality and data-driven insights, ultimately making surgeries safer and more effective.

Cylera, Inc. is a cybersecurity company focused on protecting healthcare organizations from cyber threats and malware. Founded in 2017 and headquartered in New York, Cylera offers a comprehensive platform that utilizes patented technology to provide unified cybersecurity solutions. Their software specializes in asset management, risk analysis, and threat detection, specifically designed for the healthcare Internet of Things (IoT) environment. By identifying all connected devices, analyzing vulnerabilities, and mitigating threats in real time, Cylera enables healthcare providers and other organizations to effectively manage risks and respond automatically to potential security incidents.

Epicore Biosystems, Inc. is a Cambridge, Massachusetts-based company founded in 2017 that specializes in developing and commercializing a wearable microfluidic sensing platform. This innovative technology analyzes small droplets of sweat directly from the skin to provide insights into health, hydration, and athletic performance. The platform is designed to measure various biomarkers, including proteomics and inflammatory markers, allowing for personalized management of health and nutrition. Epicore's approach leverages over two decades of research in microfluidics and soft materials conducted by leading experts at Northwestern University. By offering a non-invasive and cost-effective solution, Epicore aims to enhance athletic performance and improve overall health monitoring for users.

Droplette Inc., founded in 2017 and based in Boston, Massachusetts, specializes in the development of a needle-free skincare device that utilizes a patent-pending transdermal delivery system. This innovative technology allows for the delivery of drugs up to 60% larger than traditional treatments, penetrating deeply into the skin over large surface areas. The device is designed to be painless, contact-free, and portable, generating no disposables. Initially aimed at delivering antibiotics for serious skin conditions such as ulcers and infections, Droplette also envisions future applications for localized delivery of chemotherapeutics for skin cancer and anti-aging treatments. By enabling effective skincare without harmful chemicals, Droplette aims to transform skin health through scientific advancement.

Kinsa, Inc., established in 2012 and headquartered in San Francisco, specializes in developing smart thermometers compatible with both Android and iOS devices. Their flagship product, a low-cost, mobile-connected thermometer, facilitates communication with individuals who have recently fallen ill, providing them with necessary care information and enabling real-time health data collection to map and track disease spread.

Silvertree is focused on creating innovative wearable technology that caters to the needs of the aging population. The company designs stylish, wrist-worn devices aimed at enhancing safety and fostering connections among active older adults and their families. With a commitment to promoting dignity and independence, Silvertree targets the growing demographic of Americans aged sixty-five and older, which currently numbers around fifty-five million. By prioritizing both functionality and aesthetics, Silvertree positions itself as a leading consumer brand dedicated to the vitality and independence of older individuals.

Leo Cancer Care is focused on revolutionizing cancer radiation therapy by offering a treatment system designed to enhance patient experience and outcomes. Founded in Australia, the company leverages global research that highlights the benefits of upright patient positioning during treatment. This innovative approach shifts the traditional paradigm of machine rotation to patient rotation, allowing for a more controlled and efficient therapy process. The system integrates advanced 3D imaging and precise radiation beam management, ensuring that the appropriate amount of energy is delivered to targeted tissues. By streamlining cancer treatment and connecting patients to centralized care centers, Leo Cancer Care aims to reduce both the physical discomfort and costs typically associated with chemotherapy and radiation therapy, ultimately putting patients in control of their treatment journey.

Leo Cancer Care is focused on revolutionizing cancer radiation therapy by offering a treatment system designed to enhance patient experience and outcomes. Founded in Australia, the company leverages global research that highlights the benefits of upright patient positioning during treatment. This innovative approach shifts the traditional paradigm of machine rotation to patient rotation, allowing for a more controlled and efficient therapy process. The system integrates advanced 3D imaging and precise radiation beam management, ensuring that the appropriate amount of energy is delivered to targeted tissues. By streamlining cancer treatment and connecting patients to centralized care centers, Leo Cancer Care aims to reduce both the physical discomfort and costs typically associated with chemotherapy and radiation therapy, ultimately putting patients in control of their treatment journey.

Moons is a healthcare technology company based in Mexico City that specializes in orthodontic and dental hygiene products. Founded in 2019, the company offers innovative dental services, including the creation of personalized invisible aligners designed for each patient. Customers can visit Moons Studios for an initial consultation, where their teeth are scanned to develop a tailored treatment plan. Moons then manufactures and mails a set of 3D-printed aligners, allowing clients to straighten and whiten their teeth without the use of traditional braces. This process typically enables patients to achieve their desired smile in approximately six months, making orthodontic care more accessible and convenient.

Ascent Integrated Tech develops a hardware-enabled software platform focused on enhancing situational awareness for first responders and military personnel. Its Tactical Assault Kit (TAK) integrates with smartwatches and existing equipment to provide real-time location tracking and physiological alerting, significantly improving safety and operational decision-making during emergencies. The platform offers comprehensive monitoring and mapping capabilities in hazardous environments, enabling incident commanders to assess the status of their teams and make informed evacuation decisions through a biometric tracking system. Ascent’s technology is utilized by major metropolitan fire departments across the United States and is expanding internationally through strategic partnerships. The company is supported by government contracts and venture funding, positioning itself as a leader in redefining emergency response effectiveness.

Willow Inc., established in 2014 and headquartered in Mountain View, California, specializes in the manufacture of wearable breast pumps for women. The company offers a range of products including milk bags, accessories such as flanges and tubes, and replacement parts. Willow's flagship product is an in-bra wearable breast pump designed to provide mothers with mobility and hands-free convenience during breastfeeding. The company also provides pumping bras, cases, and other breastfeeding essentials.

Basil Systems operates a software-as-a-service platform that utilizes machine learning to analyze product, market, and regulatory data specifically for the medical device and pharmaceutical sectors. The platform offers critical analytics and insights that support strategic decision-making in product development, enhance product and supply chain quality, and minimize the risks associated with product recalls. Additionally, it aims to reduce the time required for regulatory approvals, ultimately enabling companies to deliver safe and effective products to consumers.

STIMIT AG is a medtech company based in Nidau, Switzerland, established in 2018. The company focuses on developing therapies and medical devices aimed at patients who have lost their natural breathing function, particularly those on mechanical ventilation. A significant portion of time in intensive care is dedicated to weaning patients off ventilators and restoring diaphragm function, which is critical for independent breathing. STIMIT's technology non-invasively activates the diaphragm, helping to keep it strong and functional, ultimately aiming to liberate patients from ventilators and reduce associated morbidity and mortality. Additionally, STIMIT is advancing a proprietary method for localized delivery of cancer immunotherapy, enhancing the efficacy and safety of treatment for patients with solid tumors. This dual focus positions STIMIT at the forefront of innovation in both respiratory care and oncology.

Shoulder Innovations, Inc. is a medical device company based in Holland, Michigan, specializing in orthopedic solutions for shoulder replacement surgery. Founded in 2009, the company has developed a Total Shoulder Replacement System that features innovative inset glenoid fixation technology, addressing the critical challenge of reliable fixation for glenoid implants. This technology not only enhances post-surgical implant stability, reducing the risk of revision surgeries, but also simplifies surgical instrumentation, which can lead to shorter operative times and lower costs. Shoulder Innovations markets its products through distribution partners across the United States, aiming to improve patient care and reduce overall healthcare costs.

Brio Systems, Inc., established in 2017 and headquartered in Boston, Massachusetts, specializes in COVID-19 testing solutions for workplaces. Its comprehensive platform offers on-site PCR and antibody testing, logistical support, medical oversight, and digital results communication within three days. Brio connects employers with a network of FDA-certified labs, serving industries such as manufacturing and food processing. The company's secure platform also provides diagnostic testing services for individuals, focusing on blood metrics like sugar and hormone levels, offered on a monthly subscription basis.

Brio Systems, Inc., established in 2017 and headquartered in Boston, Massachusetts, specializes in COVID-19 testing solutions for workplaces. Its comprehensive platform offers on-site PCR and antibody testing, logistical support, medical oversight, and digital results communication within three days. Brio connects employers with a network of FDA-certified labs, serving industries such as manufacturing and food processing. The company's secure platform also provides diagnostic testing services for individuals, focusing on blood metrics like sugar and hormone levels, offered on a monthly subscription basis.

Mission Bio, Inc. is a biotechnology company that specializes in tools for studying cellular heterogeneity in human health and life sciences. The company has developed the Tapestri Platform, the first single-cell multi-omics platform, which allows for the simultaneous analysis of genotype and phenotype from the same cell. This platform utilizes proprietary microfluidic droplet technology to enable precise detection of genomic variability at single-cell resolution, facilitating research in various applications, including oncology, blood cancers, solid tumors, and genome editing. Additionally, Mission Bio offers Tapestri Designer, a cloud-based tool for creating customized single-cell DNA panels, further enhancing its capabilities in targeted molecular analysis. Founded in 2011 and based in South San Francisco, California, the company was previously known as Torrent Bio, Inc. before rebranding in 2013.

Confirm is a reputable and aspirational engineering firm that offers sophisticated automation and validation solutions to manufacturing companies in the pharmaceutical, medical device, and other regulated industries. They guarantee that GMP is used in the most effective way while offering the most value in both technical and commercial terms.

Moons is a healthcare technology company based in Mexico City that specializes in orthodontic and dental hygiene products. Founded in 2019, the company offers innovative dental services, including the creation of personalized invisible aligners designed for each patient. Customers can visit Moons Studios for an initial consultation, where their teeth are scanned to develop a tailored treatment plan. Moons then manufactures and mails a set of 3D-printed aligners, allowing clients to straighten and whiten their teeth without the use of traditional braces. This process typically enables patients to achieve their desired smile in approximately six months, making orthodontic care more accessible and convenient.

Asto CT LLC specializes in developing advanced X-ray computed tomography (CT) systems aimed at enhancing equine healthcare. Founded in 2015 and based in Madison, Wisconsin, the company focuses on preventing fractures and improving the overall well-being of thoroughbreds, show horses, recreational horses, and older equines. Asto CT's technology enhances fracture risk detection, facilitates the diagnosis of lameness, and aids in the management of dental and sinus conditions. Their flagship product, Equina, delivers rapid 3D imaging of the lower limbs, head, and neck of standing horses without the need for general anesthesia, ensuring a safer and more comfortable experience for the animals. By integrating cutting-edge robotics with fan-beam CT technology, Asto CT is committed to providing high-quality diagnostic imaging that supports veterinarians in delivering effective treatments.

Excision BioTherapeutics Inc. is a life science company based in Philadelphia, Pennsylvania, established in 2015. The company specializes in developing gene editing therapeutics aimed at treating life-threatening diseases caused by neurotropic viruses. Utilizing CRISPR-based technology, Excision BioTherapeutics focuses on creating advanced gene-editing medicines that can eradicate or disrupt viral genes in human patients. The company is committed to advancing these therapeutics to ensure they are safe and effective, with the goal of significantly improving the lives of individuals affected by viral infections worldwide.

Emme, Inc. is a healthcare technology company based in San Francisco, California, focused on enhancing women's health through innovative solutions. The company has developed the Emme Smart Case and a corresponding mobile application, which together help women manage their birth control more effectively. The smart case employs multi-sensor technology to track when birth control pills are taken, alleviating the stress of remembering to take them and alerting users when back-up contraception is necessary. Additionally, the app provides a comprehensive health overview by allowing users to track their menstrual cycles, mood, and side effects. Founded in 2000, Emme aims to modernize the birth control experience for women, aligning it with contemporary technological advancements.

Notable Labs, Inc. is a clinical-stage company that specializes in personalized lab testing services for cancer patients, particularly those with brain cancer. Founded in 2014 and based in Foster City, California, the company utilizes its proprietary Predictive Precision Medicines Platform to conduct drug combination experiments on patients' tumors. This platform allows Notable Labs to simulate cancer treatments and predict patient responses to specific therapies, enabling healthcare providers to prioritize combinations of FDA-approved treatments that can be prescribed without the need for clinical trials. By providing detailed reports to physicians, Notable Labs aims to enhance treatment efficacy and expedite therapeutic development for patients.

She's Well is a fertility management service that utilizes a subscription model to assist individuals and couples in starting families at their own pace. The company partners with leading fertility centers to provide financial plans for various services, including fertility testing, IVF, egg freezing, and sperm freezing. By adopting an on-demand concierge care approach, She's Well aims to simplify the often complex and isolating fertility journey. With one in six couples facing challenges in conception and a growing trend of delayed childbirth, She’s Well addresses a significant gap in infertility services, which currently reach only a small percentage of those in need. Typical costs for treatments like IVF can be prohibitively high, often ranging from $12,000 to $20,000, with additional expenses for genetic testing. She's Well seeks to make fertility care more affordable and accessible, promoting a future where family planning is not constrained by biological timelines and where comprehensive care options are available to all who wish to conceive.

Meditrina, Inc. is a medical device company based in San Jose, California, specializing in tissue removal solutions for intrauterine pathology. Founded in 2016, the company has developed the Aveta System, an all-in-one solution designed for hysteroscopic diagnostic and therapeutic procedures. This system enables healthcare professionals to perform tasks such as the removal of polyps and fibroids in both office and operating room settings. The Aveta System features wide-angle HD hysteroscopy with electronic image-lock, advanced fluid management for better pressure and fluid control, and a compact design that allows for seamless integration into various medical environments. By providing advanced, convenient, and cost-effective options, Meditrina aims to enhance the care experience for both patients and physicians.

Vincere Health Inc. is a health technology company based in Allston, Massachusetts, founded in 2019 at the Harvard Innovation Labs. The company has developed a mobile application aimed at assisting users in quitting smoking and making healthier choices through a combination of behavioral nudges, incentives, and evidence-based interventions. Users can set personal health goals and test their adherence by using an attachable breathalyzer device to track their smoking habits daily. The platform offers immediate financial rewards for users who reduce their smoking and ultimately quit. Additionally, Vincere Health provides personalized coaching and real-time progress tracking to support chronic disease management and promote healthier lifestyle choices, addressing significant healthcare challenges primarily focused on smoking cessation.

Mahmee is an integrated care delivery platform focused on improving maternal and infant health. The company aims to address the critical gaps in the U.S. healthcare system, which faces high maternity costs and mortality rates, particularly among Black mothers and infants. By building a digital infrastructure that connects patients, independent health professionals, and healthcare organizations, Mahmee enhances access to comprehensive prenatal and postpartum care. Its platform includes a care management system that links health records for mothers and babies, flags clinical risks, and facilitates collaboration among maternity and infant care practitioners. Additionally, Mahmee’s marketplace allows new and expecting parents to discover care providers and access services both in-person and virtually, thereby supporting better health outcomes for families.

Tempo Automation Holdings, established in 2013 and headquartered in San Francisco, specializes in manufacturing low-volume electronics products. The company's core business involves designing and assembling printed circuit boards (PCBs) using a proprietary, software-automated platform. This platform enables Tempo to provide its customers, predominantly from industries such as aerospace, medical technology, and automotive, with unparalleled speed, quality, and transparency during the critical prototype and new product introduction stages. By optimizing the complex PCB manufacturing process, Tempo Automation empowers its clients to iterate quickly and bring innovative products to market more efficiently.

NeuSpera Medical Inc. specializes in the development and manufacturing of ultra-miniaturized implantable devices designed for neuromodulation therapy, focusing on treating chronic illnesses through minimally invasive solutions. The company utilizes its proprietary Mid-Field Powering technology, which harnesses the body as a natural waveguide to direct energy to the implants. This innovative approach allows for external powering of the devices, facilitating deeper and more reliable neuromodulation treatments for conditions such as Urinary Urgency Incontinence (UUI) and chronic peripheral nerve pain. Founded in 2013 and based in San Jose, California, NeuSpera Medical is committed to advancing bioelectronic medicine.

Somna Therapeutics, established in 2012 in Germantown, Wisconsin, specializes in medical devices for treating laryngopharyngeal and extraesophageal acid reflux diseases. Its flagship product, the Reza Band, is a non-pharmacological, investigational device designed to prevent reflux into the larynx, pharynx, and lungs. The company, founded in partnership with the Medical College of Wisconsin, aims to enhance the quality of life for LPR and EERD patients. Currently, Somna Therapeutics is refining the Reza Band's design and conducting clinical trials to secure FDA clearance. Post-clearance, the company plans to sell its device to hospitals, clinics, and home healthcare providers.

SleepSpace is a pioneering technology company that has developed the first Sleep Operating System, aimed at enhancing sleep quality through innovative integration of sound, vibration, and light in the smart bedroom. Its platform accurately measures sleep patterns, offering superior insights compared to traditional wearables, and is compatible with various popular devices such as Apple Watch and Oura. SleepSpace's proprietary nearable sleep sensing technology transforms smartphones into smart beds, providing valuable data for coaches and clinicians to deliver tailored sleep interventions. The platform not only facilitates clinical sleep programs but also combines objective device data with users' subjective sleep experiences. Additionally, SleepSpace has successfully partnered with leading mattress brands, hotels, and corporate wellness initiatives, while securing over $3.5 million in grants from the NIH to support its mission of improving sleep health.

Clear Labs, Inc. is a food analytics company based in Menlo Park, California, founded in 2013. The company specializes in providing a comprehensive analytics platform that analyzes the molecular contents of food and ingredients. Its offerings include Clear Dx™ and Clear Safety™, which utilize next-generation sequencing and data analytics for food safety testing and infectious disease surveillance. Clear Labs serves food manufacturers, suppliers, and retailers by ensuring transparency throughout the supply chain and testing products for various factors such as authenticity, contamination, allergens, and nutritional content. The platform delivers actionable insights that enhance safety and operational efficiency while supporting public health initiatives. Through its integrated genomics system, Clear Labs aims to simplify complex diagnostics across clinical and applied markets, making genomic insights accessible to labs, hospitals, and businesses.

Higia Technologies, founded in 2016 and based in Mexico City, develops EVA, a wearable device aimed at assessing breast cancer risk. This non-invasive device features tactile sensors that map the breast's surface and surrounding areas, enabling women to monitor changes in breast temperature, size, and weight. Equipped with biosensors, EVA continuously tracks relevant information, providing users with accessible tools for breast health management.

Farcast Biosciences, established in 2019, is a clinical diagnostic company based in Boston, Massachusetts, with a lab in Bangalore, India. The company specializes in developing and utilizing a proprietary Human Tumor Micro Dynamics (HTMD) platform. This platform preserves the tumor microenvironment using fresh, unmodified human tumor fragments and autologous blood samples, enabling oncologists and drug developers to test individual tumors and predict patient response to treatments with higher accuracy. Farcast's mission is to illuminate personalized treatment paths for cancer patients by providing precise, patient-specific data.

Bainbridge Health, Inc. is a Philadelphia-based company that develops a clinical intelligence and data analytics platform focused on improving medication safety in hospital systems. Founded in 2016, the company provides solutions specifically for medication safety leaders, including an infusion pump management software known as InfusionWare. This platform allows clinicians to manage infusion data centrally, enhancing patient safety by streamlining data handling and reducing the likelihood of medication errors. Bainbridge Health’s vendor-agnostic approach eliminates the need for cumbersome data management practices, enabling hospitals to mitigate risks associated with medication errors while also lowering avoidable costs.

New Aera, Inc. is a medical device company based in San Ramon, California, founded in 2011. It specializes in developing, manufacturing, and marketing products aimed at individuals suffering from acute respiratory conditions. One of its key offerings is the SideKick TAV, a tidal assist ventilator designed for compatibility with various oxygen sources, including concentrators and cylinders. The company's products focus on enhancing respiratory therapy to alleviate breathlessness and improve exercise endurance, ultimately supporting cardiac patients in achieving better fitness and health. As of August 2019, New Aera operates as a subsidiary of Inogen, Inc.

Emme, Inc. is a healthcare technology company based in San Francisco, California, focused on enhancing women's health through innovative solutions. The company has developed the Emme Smart Case and a corresponding mobile application, which together help women manage their birth control more effectively. The smart case employs multi-sensor technology to track when birth control pills are taken, alleviating the stress of remembering to take them and alerting users when back-up contraception is necessary. Additionally, the app provides a comprehensive health overview by allowing users to track their menstrual cycles, mood, and side effects. Founded in 2000, Emme aims to modernize the birth control experience for women, aligning it with contemporary technological advancements.

Innoblative Designs, Inc. is a medical device company based in Chicago, Illinois, with an additional office in Mansfield, Massachusetts. Founded in 2013, the company specializes in developing advanced electrosurgical devices, particularly focusing on radiofrequency ablation technology. One of its key innovations is the Sira™ device, a saline-assisted intraoperative radiofrequency ablation tool that employs bipolar current to create a controlled zone of ablation. Sira's unique design, featuring a saline microinfusion system, enhances contact with target tissue and is compatible with standard electrosurgical generators already utilized in operating rooms. This technology offers surgeons a new, effective option for intraoperative ablation of soft tissue, promoting ease of use and adoption in surgical practices.

Siris Medical, Inc. is a technology company based in Redwood City, California, that specializes in artificial intelligence-driven decision support systems for radiation therapy in cancer treatment. Founded in 2013, the company has developed the InsightRT Software Suite, which includes tools such as QuickMatch and PlanMD, designed to assist clinicians in managing patient treatment plans effectively. This platform is notable for being the first artificial intelligence decision support system in radiation oncology to receive FDA 510(k) clearance. It employs machine learning to provide real-time insights into treatment plan outcomes, helping clinicians make informed decisions regarding dosage, prescription, and treatment modalities, ultimately aiming to minimize side effects and expedite the initiation of patient treatment. Siris Medical is also affiliated with various innovation incubators, including North Shore InnoVentures and the UCSF / QB3 Rosenman program.

NeuSpera Medical Inc. specializes in the development and manufacturing of ultra-miniaturized implantable devices designed for neuromodulation therapy, focusing on treating chronic illnesses through minimally invasive solutions. The company utilizes its proprietary Mid-Field Powering technology, which harnesses the body as a natural waveguide to direct energy to the implants. This innovative approach allows for external powering of the devices, facilitating deeper and more reliable neuromodulation treatments for conditions such as Urinary Urgency Incontinence (UUI) and chronic peripheral nerve pain. Founded in 2013 and based in San Jose, California, NeuSpera Medical is committed to advancing bioelectronic medicine.

ActiveProtective is a consumer device company that produces smart garments to reduce traumatic injury using wearable airbag technology. The company's proprietary technology uses 3D motion sensors to determine the stereotypical motions and accelerations that govern the body’s normal, daily activities, in order to determine ’departures’ from what is allowable. This technique called "fall disambiguation", allows users to determine falls prior to impact, intercept hip fractures, and protect themselves from risks during sports and military sessions by deploying micro-airbag protection. ActiveProtective was founded in 2006 and is based in Allentown, Pennsylvania.

Center Health focuses on advancing diabetes management through innovative technology. The company has developed an AI-driven assistant and a connected blood sugar meter that allows users to monitor their glucose levels effectively. This device not only facilitates real-time tracking of blood sugar but also helps users maintain records and analyze how daily activities influence their glucose levels. By promoting simple logging and collaboration, Center Health aims to provide personalized insights, enhancing the overall experience for individuals managing diabetes. Ultimately, the company's goal is to empower patients to take control of their health and improve their quality of life.

Celularity is a clinical-stage biotechnology company focused on advancing cellular medicine through the development of off-the-shelf placental-derived allogeneic cell therapies. Its product pipeline includes unmodified and genetically modified natural killer (NK) cells, CAR-engineered T cells, and mesenchymal-like adherent stromal cells. The company targets various health conditions, including cancer, immunologic disorders, infectious diseases, and degenerative illnesses. Celularity leverages the unique biology of the placenta, aiming to create effective and accessible therapies to address significant unmet medical needs. In addition to its cell therapy initiatives, Celularity operates a bio-banking segment, which contributes substantially to its revenue.

Respiratory Motion, Inc. is a medical device company based in Waltham, Massachusetts, that specializes in the development and commercialization of respiratory monitoring devices. Founded in 2011, the company offers the ExSpiron, a point-of-care device designed to non-invasively measure critical respiratory parameters such as minute ventilation, tidal volume, and respiratory rate. With FDA clearance for its continuous monitoring systems, Respiratory Motion provides healthcare professionals with real-time data that enhances patient safety and helps in the early detection of respiratory collapse across various patient populations and clinical settings.

Innoblative Designs, Inc. is a medical device company based in Chicago, Illinois, with an additional office in Mansfield, Massachusetts. Founded in 2013, the company specializes in developing advanced electrosurgical devices, particularly focusing on radiofrequency ablation technology. One of its key innovations is the Sira™ device, a saline-assisted intraoperative radiofrequency ablation tool that employs bipolar current to create a controlled zone of ablation. Sira's unique design, featuring a saline microinfusion system, enhances contact with target tissue and is compatible with standard electrosurgical generators already utilized in operating rooms. This technology offers surgeons a new, effective option for intraoperative ablation of soft tissue, promoting ease of use and adoption in surgical practices.

Kinsa, Inc., established in 2012 and headquartered in San Francisco, specializes in developing smart thermometers compatible with both Android and iOS devices. Their flagship product, a low-cost, mobile-connected thermometer, facilitates communication with individuals who have recently fallen ill, providing them with necessary care information and enabling real-time health data collection to map and track disease spread.

Clear Labs, Inc. is a food analytics company based in Menlo Park, California, founded in 2013. The company specializes in providing a comprehensive analytics platform that analyzes the molecular contents of food and ingredients. Its offerings include Clear Dx™ and Clear Safety™, which utilize next-generation sequencing and data analytics for food safety testing and infectious disease surveillance. Clear Labs serves food manufacturers, suppliers, and retailers by ensuring transparency throughout the supply chain and testing products for various factors such as authenticity, contamination, allergens, and nutritional content. The platform delivers actionable insights that enhance safety and operational efficiency while supporting public health initiatives. Through its integrated genomics system, Clear Labs aims to simplify complex diagnostics across clinical and applied markets, making genomic insights accessible to labs, hospitals, and businesses.

Pelvalon is a medical device company focused on improving the lives of women affected by fecal incontinence and pelvic floor disorders. The company develops non-surgical therapy devices that do not contain drugs or hormones, providing effective treatment options for accidental bowel leakage. By addressing the specific needs of female pelvic and bowel health, Pelvalon aims to enhance bowel control and overall well-being for its patients.

Whistle Labs is a San Francisco-based technology company focused on enhancing pet health and longevity through innovative solutions. The company develops on-collar devices that enable pet owners to monitor their pets' daily activities, including walking, playing, and resting. By analyzing this data, Whistle provides insights into the behavioral patterns and long-term health trends of pets, establishing a new standard for preventative care. Led by a team of dedicated technologists, Whistle Labs aims to transform veterinary medical research by leveraging a comprehensive database of pet health information, ultimately contributing to a healthier and longer life for pets.

Whistle Labs is a San Francisco-based technology company focused on enhancing pet health and longevity through innovative solutions. The company develops on-collar devices that enable pet owners to monitor their pets' daily activities, including walking, playing, and resting. By analyzing this data, Whistle provides insights into the behavioral patterns and long-term health trends of pets, establishing a new standard for preventative care. Led by a team of dedicated technologists, Whistle Labs aims to transform veterinary medical research by leveraging a comprehensive database of pet health information, ultimately contributing to a healthier and longer life for pets.