Synaffix BV is a biotechnology company that develops antibody-drug conjugate (ADC) technology platforms for oncology. It offers GlycoConnect, a site-specific antibody conjugation technology that modifies naturally-occurring glycan anchor points that exist on various antibodies to facilitate site-specific and stable conjugation of potent anti-cancer molecules. The company also offers HydraSpace, a payload-enhancing linker technology that is used to reduce ADC aggregation potential, increase payload solubility, improve conjugation efficiency, and enable higher drug loading. In addition, it offers a metal-free click chemistry that is applicable across pharma, biotech, and academic groups. The company was founded in 2010 and is based in Oss, the Netherlands.