Arboretum Ventures

Shoulder Innovations, Inc. is a medical device company based in Holland, Michigan, specializing in orthopedic solutions for shoulder replacement surgery. Founded in 2009, the company has developed an advanced Total Shoulder Replacement System that features innovative inset glenoid fixation technology, addressing the critical issue of glenoid implant stability during shoulder arthroplasty. This technology not only enhances the robustness of the glenoid platform but also simplifies the surgical instrumentation, aiming to reduce operative time and costs. The company's products are marketed through distribution partners in the United States and are designed to improve patient outcomes by minimizing the risk of glenoid loosening, which is a leading cause of revision surgeries. By focusing on reliable fixation and simplified surgical techniques, Shoulder Innovations strives to enhance the efficacy and longevity of shoulder implants while potentially lowering overall healthcare costs.

Francis Medical, Inc., established in 2018 and based in Maple Grove, Minnesota, specializes in the development of innovative medical devices utilizing water vapor technology to treat various urological cancers. The company focuses on prostate, kidney, and bladder cancers, aiming to provide minimally invasive treatments that can potentially reduce life-altering side effects common with traditional methods. Their approach involves using the thermal energy stored in sterile water vapor to ablate cancerous tissue via a simple transurethral procedure.

Orasis Pharmaceuticals Ltd is a pharmaceutical company based in Herzliya, Israel, founded in 2015. The company specializes in the development of corrective eye drops aimed at treating presbyopia, a common age-related vision condition. Its primary product, CSF-1, is designed to improve near visual acuity through pupil modulation, thereby alleviating the need for reading glasses. By repurposing existing, well-studied molecules, CSF-1 aims to provide an effective, safe, and easy-to-use solution that enhances the quality of life for individuals affected by presbyopia. This noninvasive treatment option offers patients a practical alternative for managing their near vision difficulties.

RareCyte, Inc. is a life sciences company based in Seattle, Washington, founded in 2009. The company specializes in developing advanced platforms for liquid and tissue biopsy analysis, focusing on the detection and characterization of rare cells, particularly circulating tumor cells (CTCs) and circulating endothelial cells (CECs) in blood samples. RareCyte's AccuCyte system provides an open platform that facilitates the unbiased discovery and isolation of these rare cells, supporting various applications in cancer research, cardiovascular disease studies, and diagnostic development. The company offers a range of products, including sample preparation systems, staining kits, automated fluorescence microscopy instruments, and slide imaging systems. By enabling precision medicine approaches, RareCyte aims to provide new tools for medical professionals and researchers to address complex questions in the fields of cancer and other therapeutic areas.

AtaCor Medical, Inc. is a medical device company based in San Clemente, California, specializing in innovative solutions for cardiac pacing and rhythm management. Founded in 2014, the company has developed the AtaCor EV Temporary Pacing System, which allows for temporary pacing through a parasternal approach. This system advances a custom pacing lead into the extracardiac tissue between the ribs and pericardium, effectively restoring cardiac rhythm without the need for traditional pacing leads or hardware that typically attach directly to the heart. By facilitating quick deployment of temporary or emergency pacing therapy, AtaCor Medical addresses critical needs in cardiac care.

ViaLase is a medical technology company that specializes in developing an image-guided femtosecond laser surgical system for the treatment of open-angle glaucoma. Founded in 2019 and based in Corona Del Mar, California, the company focuses on utilizing micron-resolution optical coherence tomography (OCT) technology. This innovative approach enables the creation of customized, micron-sized drainage channels through the trabecular meshwork, connecting the anterior chamber to Schlemm's canal without the need for surgical penetration or opening of the eye. By offering an efficient and non-invasive treatment option, ViaLase aims to enhance the management of glaucoma for medical professionals and their patients.

Flosonics Medical is a Canadian medical device company founded in 2017, specializing in the development of non-invasive sensors aimed at enhancing the management of critically ill patients. Its flagship product, the FloPatch, is a wearable ultrasound sensor designed to monitor blood flow in patients post-clinical intervention, thereby addressing critical clinical needs. The FloPatch is particularly beneficial for healthcare professionals, including physicians, nurses, and paramedics, operating in various high-pressure environments such as ambulances, emergency departments, operating rooms, and intensive care units. The device is notable for its portability, wireless connectivity with tablets and other medical equipment, and user-friendly functionality, all of which contribute to improved patient care in urgent medical situations. Flosonics Medical, previously known as Ke2 Technologies, rebranded in September 2017.

Reprieve Cardiovascular, Inc. is a medical device company based in Milford, Massachusetts, established in 2018. The company specializes in developing innovative fluid management technologies aimed at treating congestive heart failure. Its flagship product, the Reprieve technology, offers a solution for clinicians to precisely control the fluid volume in patients suffering from acute decompensated heart failure (ADHF). This ability to manage fluid levels is essential for improving cardiac care and assisting in the decongestion process for these patients. Reprieve Cardiovascular operates as a subsidiary of CardioRenal Systems, Inc.

Avation Medical, Inc. is a company focused on developing a non-invasive closed-loop neuromodulation system aimed at treating overactive bladder in a home setting. Incorporated in 2016 and based in Columbus, Ohio, Avation Medical is at the forefront of innovation in wearable nerve stimulation systems. The company emphasizes empowering patients to manage their therapies, facilitating a more personalized approach to care. By leveraging advanced technologies, Avation Medical seeks to transform the neuromodulation market, enhancing the quality of care for individuals with chronic conditions through patient-centric solutions.

Virtual Incision is a medical technology company focused on developing innovative robotic-assisted surgical devices, specifically targeting colon resection. The company has created the MIRA (Miniaturized In vivo Robotic Assistant) Platform, which is a pioneering miniaturized surgical robotic support device. This platform allows for efficient operating room setups in minutes, eliminating the need for cumbersome equipment handling such as draping or docking. By enhancing the surgical process, Virtual Incision aims to improve clinical outcomes while also addressing healthcare costs, positioning itself as a leader in the field of robotic-assisted surgery.

Convergent Dental, Inc. is a dental equipment and technology company based in Needham, Massachusetts, founded in 2011. The company specializes in developing Solea, a computer-aided CO2 laser system designed for both hard and soft tissue dental procedures. This innovative system offers a quieter and more precise cutting experience compared to traditional laser systems, enhancing patient comfort during dental surgeries. By utilizing patented technologies and advanced computer controls, Convergent Dental aims to improve the efficiency of dental treatments while transforming the overall patient experience.

Cardiac Dimensions, Inc. is a medical device company focused on developing innovative minimally invasive treatments for heart failure and associated cardiovascular issues. Founded in 2000 and headquartered in Kirkland, Washington, with additional operations in Sydney, Australia, and Offenbach, Germany, the company is known for its Carillon Mitral Contour System. This permanent implant is designed specifically for the treatment of functional mitral regurgitation, utilizing a catheter-based approach to reshape the mitral valve and effectively reduce regurgitation. By providing a non-surgical option for patients, Cardiac Dimensions aims to improve outcomes for those suffering from heart-related conditions.

BrightSpec is a company based in Charlottesville, Virginia, specializing in advanced analytical chemistry solutions through its innovative Fourier transform molecular rotational resonance (FT-MRR) spectroscopy platform. This technology, developed by researchers at the University of Virginia, enables comprehensive characterization of chemical molecules, with the capability to differentiate between stereoisomers and isotopes. BrightSpec's platform addresses high-value, time-sensitive analytical challenges that conventional spectroscopy techniques struggle to meet. By eliminating the need for reference samples or separations, its solutions enhance the analysis of complex mixtures, making them particularly valuable for applications in manufacturing process control, quality assurance, environmental monitoring, and formulation research. The company aims to improve the efficiency and accuracy of chemical analysis, thereby transforming the landscape of sample analytics in various industries.

Boomerang Medical is a female-led bioelectronic medical technology company based in Mountain View, California, on the campus of El Camino Hospital. The firm is dedicated to revolutionizing the management of autoimmune diseases through the development of innovative bioelectric neuromodulation technologies. Boomerang Medical's commitment to advancing treatment options is underscored by its receipt of Breakthrough Device Designation from the FDA for its technology aimed at treating Crohn's disease and ulcerative colitis. By focusing on improving the quality of life for patients, Boomerang Medical seeks to disrupt traditional treatment paradigms in the field of autoimmune illnesses.

Delphinus Medical Technologies, Inc. is a medical imaging company based in Plymouth, Michigan, with an additional office in Sunnyvale, California. Founded in 2009, the company specializes in developing and commercializing innovative breast cancer screening solutions. Its flagship product, SoftVue, employs a unique circular array transducer technology that utilizes ultrasound to provide three-dimensional and tomographic imaging of the entire breast. This system is designed to differentiate between benign and malignant masses, assess breast cancer risks, and monitor treatment, all while ensuring a comfortable experience for patients without the use of radiation. Delphinus serves hospitals and imaging clinics both in the United States and internationally, aiming to improve early detection and diagnosis of breast cancer.

Navv Systems provides healthcare-focused indoor location technology with the NavvTrack platform. Integrated with Apple Maps, NavvTrack empowers hospitals with high-resolution indoor maps and tools to easily locate and manage staff, equipment, and resources. Developed at Henry Ford Innovations in Detroit, Michigan, NavvTrack is deployed in multiple U.S. hospitals, where it streamlines enterprise device management, helps coordinate team workflows and reduces operational costs.

Enumera Molecular is a life science tools company based in Ann Arbor, Michigan, that focuses on developing a scalable biomolecule assessment platform aimed at enhancing clinical diagnostics. The company’s innovative platform simplifies complex molecular testing, enabling lower-cost and rapid clinical liquid biopsy tests. By transforming the field of clinical molecular testing, Enumera Molecular provides physicians with a more actionable tool, ultimately improving patient care and streamlining the diagnostic process.

Koya Medical, Inc. is a healthcare company based in Oakland, California, founded in 2018. The company specializes in developing innovative wearable therapeutic devices aimed at treating cancer-related chronic lymphedema and various venous diseases. Koya Medical's technology offers active compression therapy that enhances mobility and personalized care, addressing limitations commonly associated with traditional compression methods. Its sensor-based closed-loop system provides patient-specific patterned compression, enabling healthcare providers to effectively manage conditions like chronic edema and chronic venous insufficiency. Through its breakthrough treatments, Koya Medical seeks to transform the standard of care for individuals affected by these debilitating conditions.

ViaLase is a medical technology company that specializes in developing an image-guided femtosecond laser surgical system for the treatment of open-angle glaucoma. Founded in 2019 and based in Corona Del Mar, California, the company focuses on utilizing micron-resolution optical coherence tomography (OCT) technology. This innovative approach enables the creation of customized, micron-sized drainage channels through the trabecular meshwork, connecting the anterior chamber to Schlemm's canal without the need for surgical penetration or opening of the eye. By offering an efficient and non-invasive treatment option, ViaLase aims to enhance the management of glaucoma for medical professionals and their patients.

Convergent Dental, Inc. is a dental equipment and technology company based in Needham, Massachusetts, founded in 2011. The company specializes in developing Solea, a computer-aided CO2 laser system designed for both hard and soft tissue dental procedures. This innovative system offers a quieter and more precise cutting experience compared to traditional laser systems, enhancing patient comfort during dental surgeries. By utilizing patented technologies and advanced computer controls, Convergent Dental aims to improve the efficiency of dental treatments while transforming the overall patient experience.

Boomerang Medical is a female-led bioelectronic medical technology company based in Mountain View, California, on the campus of El Camino Hospital. The firm is dedicated to revolutionizing the management of autoimmune diseases through the development of innovative bioelectric neuromodulation technologies. Boomerang Medical's commitment to advancing treatment options is underscored by its receipt of Breakthrough Device Designation from the FDA for its technology aimed at treating Crohn's disease and ulcerative colitis. By focusing on improving the quality of life for patients, Boomerang Medical seeks to disrupt traditional treatment paradigms in the field of autoimmune illnesses.

Akadeum Life Sciences, Inc. is a life sciences company based in Ann Arbor, Michigan, specializing in the manufacturing of microbubble cell separation products. Founded in 2014, the company develops bioseparation products that utilize microscopic microbubbles to efficiently capture and isolate target cells from biological samples. Their offerings include T cell and B cell isolation kits for both human and mouse cells, as well as depletion microbubbles for red blood cell separation. Akadeum's products streamline the process of removing specific cells, such as bacteria or viruses, from liquid samples, thereby enhancing the efficiency of downstream testing and analysis. The company also collaborates with strategic partners, including Agilent Technologies, to further advance its innovative solutions in cell separation. Akadeum Life Sciences sells its products online, aiming to improve cell-based research and diagnostics in the life sciences sector.

Francis Medical, Inc., established in 2018 and based in Maple Grove, Minnesota, specializes in the development of innovative medical devices utilizing water vapor technology to treat various urological cancers. The company focuses on prostate, kidney, and bladder cancers, aiming to provide minimally invasive treatments that can potentially reduce life-altering side effects common with traditional methods. Their approach involves using the thermal energy stored in sterile water vapor to ablate cancerous tissue via a simple transurethral procedure.

Allay Therapeutics is focused on developing innovative solutions for post-surgical pain management, aiming to enhance patient recovery experiences. The company utilizes a proprietary technology platform that integrates validated non-opioid analgesics with biopolymers to create dissolvable therapeutics. These products are designed to deliver targeted pain relief over extended periods, significantly surpassing the duration of existing pain treatments. Allay's lead investigational product, ATX101, is currently undergoing evaluation in a Phase 2 clinical study for total knee arthroplasty surgeries. With a diverse team of entrepreneurs, scientists, and clinicians based in the San Francisco Bay Area and Singapore, Allay Therapeutics seeks to address the limitations of conventional pain management approaches, particularly the challenges associated with opioid use.

RareCyte, Inc. is a life sciences company based in Seattle, Washington, founded in 2009. The company specializes in developing advanced platforms for liquid and tissue biopsy analysis, focusing on the detection and characterization of rare cells, particularly circulating tumor cells (CTCs) and circulating endothelial cells (CECs) in blood samples. RareCyte's AccuCyte system provides an open platform that facilitates the unbiased discovery and isolation of these rare cells, supporting various applications in cancer research, cardiovascular disease studies, and diagnostic development. The company offers a range of products, including sample preparation systems, staining kits, automated fluorescence microscopy instruments, and slide imaging systems. By enabling precision medicine approaches, RareCyte aims to provide new tools for medical professionals and researchers to address complex questions in the fields of cancer and other therapeutic areas.

Strata Oncology, Inc. is a precision oncology company focused on enhancing cancer care by facilitating access to precision medicine clinical trials and expediting drug approval processes. Based in Ann Arbor, Michigan, the company develops a comprehensive precision oncology platform that supports routine testing and efficient use of molecular data. Strata's offerings include The Strata Trial, a genomic testing program for systematic precision oncology implementation, and StrataNGS, a targeted assay for sequencing DNA and RNA from biopsies. Additionally, StrataPOINT integrates electronic medical record histories with molecular profiling to ensure eligible patients are tested and considered for trial enrollment. The company features a portfolio of pharma-sponsored therapeutic protocols, known as Strata Partnered Trials, aligned to specific biomarkers. Strata also operates The Strata Lab, a cancer sequencing facility, and maintains the Strata Precision Oncology Network, a collaborative entity aimed at promoting precision medicine initiatives. Formerly known as Strata Oncology Research, Inc., the company rebranded in 2016 and has been incorporated since 2015.

Navv Systems provides healthcare-focused indoor location technology with the NavvTrack platform. Integrated with Apple Maps, NavvTrack empowers hospitals with high-resolution indoor maps and tools to easily locate and manage staff, equipment, and resources. Developed at Henry Ford Innovations in Detroit, Michigan, NavvTrack is deployed in multiple U.S. hospitals, where it streamlines enterprise device management, helps coordinate team workflows and reduces operational costs.

Flosonics Medical is a Canadian medical device company founded in 2017, specializing in the development of non-invasive sensors aimed at enhancing the management of critically ill patients. Its flagship product, the FloPatch, is a wearable ultrasound sensor designed to monitor blood flow in patients post-clinical intervention, thereby addressing critical clinical needs. The FloPatch is particularly beneficial for healthcare professionals, including physicians, nurses, and paramedics, operating in various high-pressure environments such as ambulances, emergency departments, operating rooms, and intensive care units. The device is notable for its portability, wireless connectivity with tablets and other medical equipment, and user-friendly functionality, all of which contribute to improved patient care in urgent medical situations. Flosonics Medical, previously known as Ke2 Technologies, rebranded in September 2017.

EQRx, Inc. is a biotechnology company based in Cambridge, Massachusetts, established in 2019. The company focuses on re-engineering the drug discovery and delivery process to provide a market-based solution to the escalating costs of medications. EQRx aims to enhance the efficiency and affordability of high-quality, patent-protected medicines by collaborating with various stakeholders across the healthcare system and leveraging advancements in science and technology. The company has developed a robust pipeline with over ten programs, including clinical and preclinical projects targeting oncology and immune-inflammatory conditions, featuring compounds such as Aumolertinib, Lerociclib, Sugemalimab, and Nofazinlimab.

Koya Medical, Inc. is a healthcare company based in Oakland, California, founded in 2018. The company specializes in developing innovative wearable therapeutic devices aimed at treating cancer-related chronic lymphedema and various venous diseases. Koya Medical's technology offers active compression therapy that enhances mobility and personalized care, addressing limitations commonly associated with traditional compression methods. Its sensor-based closed-loop system provides patient-specific patterned compression, enabling healthcare providers to effectively manage conditions like chronic edema and chronic venous insufficiency. Through its breakthrough treatments, Koya Medical seeks to transform the standard of care for individuals affected by these debilitating conditions.

Jumpcode Genomics is a biotechnology company founded in 2016 by Keith Brown in Carlsbad, California. The company specializes in genome technology, focusing on enhancing the performance of sequencing workflows. Its proprietary technology, CRISPRclean, utilizes the CRISPR/Cas system to selectively deplete unwanted nucleic acid molecules from sequencing libraries. This innovation improves detection sensitivity, reduces bias, and simplifies overall workflows while maintaining the integrity of non-targeted sequences. By integrating seamlessly with standard library preparation services, Jumpcode Genomics aims to provide researchers with more effective tools for decoding and addressing complex biological challenges.

Cardiac Dimensions, Inc. is a medical device company focused on developing innovative minimally invasive treatments for heart failure and associated cardiovascular issues. Founded in 2000 and headquartered in Kirkland, Washington, with additional operations in Sydney, Australia, and Offenbach, Germany, the company is known for its Carillon Mitral Contour System. This permanent implant is designed specifically for the treatment of functional mitral regurgitation, utilizing a catheter-based approach to reshape the mitral valve and effectively reduce regurgitation. By providing a non-surgical option for patients, Cardiac Dimensions aims to improve outcomes for those suffering from heart-related conditions.

Health Scholars, Inc. is a company that specializes in developing medical simulation training software aimed at enhancing clinical education and training for healthcare providers. Incorporated in 2017 and based in Westminster, Colorado, Health Scholars offers a range of virtual reality (VR) solutions, including pre-hospital and in-hospital advanced cardiovascular life support (ACLS) training for first responders and clinicians, respectively. Additionally, the company provides The OR, a VR training program focused on surgical fire prevention to help mitigate risks and reduce liability costs. Their platform is designed to be user-friendly and scalable across health systems, facilitating the management and delivery of interactive training content. By leveraging VR technology, Health Scholars enables healthcare professionals to engage in cost-effective and immersive training experiences that improve patient care outcomes.

EQRx, Inc. is a biotechnology company based in Cambridge, Massachusetts, established in 2019. The company focuses on re-engineering the drug discovery and delivery process to provide a market-based solution to the escalating costs of medications. EQRx aims to enhance the efficiency and affordability of high-quality, patent-protected medicines by collaborating with various stakeholders across the healthcare system and leveraging advancements in science and technology. The company has developed a robust pipeline with over ten programs, including clinical and preclinical projects targeting oncology and immune-inflammatory conditions, featuring compounds such as Aumolertinib, Lerociclib, Sugemalimab, and Nofazinlimab.

Fifth Eye Inc. is a medical software company based in Ann Arbor, Michigan, specializing in real-time analytics for patient health monitoring. The company develops an innovative clinical decision support system that continuously analyzes a patient's hemodynamic status to predict the risk of instability. Its advanced software utilizes artificial intelligence to process real-time ECG data, enabling minute-to-minute assessments and providing healthcare professionals with early warnings of potential complications hours in advance of traditional methods. By offering continuous patient trajectory forecasts and historical trend analyses without requiring electronic health record inputs, Fifth Eye aims to enhance proactive patient care, improve clinical outcomes, and reduce hospital costs. Formerly known as Trove Analytics, Inc., Fifth Eye was incorporated in 2017 and rebranded in June 2018.

Lucina Health, Inc. is a data-driven enterprise software company that specializes in maternity analytics. The company provides a platform that aggregates and analyzes patient and population data in real-time, aimed at health plans, Medicaid providers, and public entities. Central to its offerings is Firefly, a platform designed to identify women at risk of preterm birth, typically within the first trimester, and to deliver personalized health improvement resources. Additionally, Lucina Health offers a companion mobile app that facilitates communication between patients and the Firefly platform, empowering women to take charge of their pregnancy. By focusing on early intervention and optimizing care management, Lucina Health aims to improve birth outcomes and foster healthier communities. Established in 2008 and based in Louisville, Kentucky, Lucina Health was formerly known as Cervilenz Inc. and rebranded in 2015. As of January 2020, the company operates as a subsidiary of Unified Women's Healthcare LLC.

Pear Therapeutics, Inc. is a Boston-based commercial-stage healthcare company specializing in software-based digital therapeutics, also known as Prescription Digital Therapeutics (PDTs). Founded in 2013, the company develops clinically validated software solutions designed to treat a range of behavioral health disorders, including addiction, anxiety, depression, and chronic insomnia. Its suite of products includes mobile digital therapies that reward patients for engagement, and specific tools like reSET and reSET-O, aimed at treating substance use disorders. The company also offers Somryst, which provides neurobehavioral interventions for insomnia, and operates PearConnect, a patient services center that connects patients with advocates and resources, ensuring support throughout their treatment journey. Pear Therapeutics aims to enhance treatment outcomes by integrating digital therapies with pharmaceuticals and providing comprehensive support for patients, clinicians, and payors.

SonarMD, LLC, based in Elgin, Illinois, develops a subspecialty practice platform focused on care coordination for patients with chronic conditions, particularly those related to gut health. The company offers services designed to improve the management of complex chronic diseases that often require high-cost medications. By enhancing patient engagement and optimizing specialty pharmacy resources, SonarMD aims to keep patients healthier and reduce hospitalizations. Their approach integrates care management solutions that streamline the healthcare experience for both patients and clinical teams, ultimately fostering better health outcomes.

Francis Medical, Inc., established in 2018 and based in Maple Grove, Minnesota, specializes in the development of innovative medical devices utilizing water vapor technology to treat various urological cancers. The company focuses on prostate, kidney, and bladder cancers, aiming to provide minimally invasive treatments that can potentially reduce life-altering side effects common with traditional methods. Their approach involves using the thermal energy stored in sterile water vapor to ablate cancerous tissue via a simple transurethral procedure.

Strata Oncology, Inc. is a precision oncology company focused on enhancing cancer care by facilitating access to precision medicine clinical trials and expediting drug approval processes. Based in Ann Arbor, Michigan, the company develops a comprehensive precision oncology platform that supports routine testing and efficient use of molecular data. Strata's offerings include The Strata Trial, a genomic testing program for systematic precision oncology implementation, and StrataNGS, a targeted assay for sequencing DNA and RNA from biopsies. Additionally, StrataPOINT integrates electronic medical record histories with molecular profiling to ensure eligible patients are tested and considered for trial enrollment. The company features a portfolio of pharma-sponsored therapeutic protocols, known as Strata Partnered Trials, aligned to specific biomarkers. Strata also operates The Strata Lab, a cancer sequencing facility, and maintains the Strata Precision Oncology Network, a collaborative entity aimed at promoting precision medicine initiatives. Formerly known as Strata Oncology Research, Inc., the company rebranded in 2016 and has been incorporated since 2015.

Cardiac Dimensions, Inc. is a medical device company focused on developing innovative minimally invasive treatments for heart failure and associated cardiovascular issues. Founded in 2000 and headquartered in Kirkland, Washington, with additional operations in Sydney, Australia, and Offenbach, Germany, the company is known for its Carillon Mitral Contour System. This permanent implant is designed specifically for the treatment of functional mitral regurgitation, utilizing a catheter-based approach to reshape the mitral valve and effectively reduce regurgitation. By providing a non-surgical option for patients, Cardiac Dimensions aims to improve outcomes for those suffering from heart-related conditions.

BioIQ, founded in 2005 and based in Atlanta, Georgia, is a health improvement technology company focused on enhancing corporate health and wellness programs. It offers a unique health screening platform and an ecosystem of tools designed to provide quantifiable wellness insights. BioIQ's solutions include humanized analytics, omnichannel communications, and care navigation services for health plans, employers, and government entities. The company collaborates with major employers and health companies across the United States, having successfully launched over 3,000 health improvement programs.

Pear Therapeutics, Inc. is a Boston-based commercial-stage healthcare company specializing in software-based digital therapeutics, also known as Prescription Digital Therapeutics (PDTs). Founded in 2013, the company develops clinically validated software solutions designed to treat a range of behavioral health disorders, including addiction, anxiety, depression, and chronic insomnia. Its suite of products includes mobile digital therapies that reward patients for engagement, and specific tools like reSET and reSET-O, aimed at treating substance use disorders. The company also offers Somryst, which provides neurobehavioral interventions for insomnia, and operates PearConnect, a patient services center that connects patients with advocates and resources, ensuring support throughout their treatment journey. Pear Therapeutics aims to enhance treatment outcomes by integrating digital therapies with pharmaceuticals and providing comprehensive support for patients, clinicians, and payors.

Swift Biosciences Inc. is a biotechnology company based in Ann Arbor, Michigan, that specializes in the development and commercialization of next-generation sequencing (NGS) library preparation kits for genomics, translational, and clinical research. The company focuses on creating innovative molecular biology reagents, protocols, and diagnostic tools to enhance the efficiency and accuracy of genomic analysis. Its product offerings include various RNA and DNA library preparation kits, amplicon panels, hybridization capture kits, and specialized tools for cancer gene profiling and metagenomics. Swift Biosciences' technologies aim to streamline sample preparation processes and improve data quality from NGS instruments, supporting a wide range of applications such as circulating tumor cells and whole-genome sequencing. The company distributes its products through a network of distributors across Asia Pacific, Europe, the Middle East, and South America. Established in 2009, Swift Biosciences is committed to advancing molecular research and diagnostics.

Aira is a company dedicated to enhancing accessibility for individuals who are blind or have low vision. It offers remote visual interpretation services through a user-friendly app that connects users with highly trained Visual Interpreters. By utilizing a smartphone's camera, users can stream live video to these interpreters, who assist them in navigating various daily activities safely and efficiently. Additionally, Aira has developed wearable smart glasses that link users to a network of certified agents, providing real-time visual assistance via an augmented reality dashboard. This innovative approach empowers visually impaired individuals to perform tasks such as navigating busy streets and recognizing faces, ultimately promoting greater mobility and independence in their everyday lives.

Ebb Therapeutics, Inc. is a company specializing in the development of a regional cerebral thermal therapy (RCTT) device aimed at addressing insomnia and sleep disorders. It offers the Ebb Insomnia Therapy, which is a drug-free solution designed to help individuals improve their sleep quality. Founded in 2008 and originally known as Cereve, Inc., the company is headquartered in Pittsburgh, Pennsylvania. Ebb Therapeutics focuses on innovative therapeutic approaches to enhance sleep health without the reliance on pharmaceuticals.

ConcertoCare is dedicated to delivering primary and complex care to seniors and other adult patients with unmet health and social needs. The company employs a tech-enabled, value-based care model that features three distinct in-home care approaches, all supported by its proprietary population health and analytics platform. ConcertoCare's interdisciplinary teams, led by experienced professionals in home-based geriatric medicine, digital health, palliative care, and healthcare analytics, utilize clinical decision support tools to enhance patient care. This innovative model aims to lower overall healthcare costs while improving health outcomes for its patients.

nVision Medical Corporation is a privately-held medical device company based in Saratoga, California, focused on advancing women's health innovation. Established in 2009, the company specializes in developing devices to assess and treat female infertility resulting from fallopian tube dysfunction. nVision's products are designed not only to detect conditions such as ovarian cancer and tube blockage but also to address the challenges faced in diagnosing and treating issues within the female reproductive tract. By concentrating on these critical areas, nVision aims to improve clinical outcomes and enhance the overall health of women. As of 2018, nVision Medical operates as a subsidiary of Boston Scientific Corporation.

SI-BONE, Inc. is a medical device company based in Santa Clara, California, that specializes in the development and commercialization of implantable devices for surgical treatment of sacropelvic anatomy. Founded in 2008, the company offers a range of patented titanium implants, including the iFuse system, which is designed for the minimally invasive fusion of the sacroiliac joint to alleviate dysfunction that leads to lower back pain. The iFuse implant procedure is noted for its reduced invasiveness and efficiency compared to traditional open fusion methods. In addition to the iFuse system, SI-BONE develops other products such as iFuse-3D, iFuse-TORQ, and iFuse Bedrock Granite, which address various conditions related to sacroiliac joint dysfunction, spinal deformity, and pelvic trauma. The company operates both in the United States and internationally.

Strata Oncology, Inc. is a precision oncology company focused on enhancing cancer care by facilitating access to precision medicine clinical trials and expediting drug approval processes. Based in Ann Arbor, Michigan, the company develops a comprehensive precision oncology platform that supports routine testing and efficient use of molecular data. Strata's offerings include The Strata Trial, a genomic testing program for systematic precision oncology implementation, and StrataNGS, a targeted assay for sequencing DNA and RNA from biopsies. Additionally, StrataPOINT integrates electronic medical record histories with molecular profiling to ensure eligible patients are tested and considered for trial enrollment. The company features a portfolio of pharma-sponsored therapeutic protocols, known as Strata Partnered Trials, aligned to specific biomarkers. Strata also operates The Strata Lab, a cancer sequencing facility, and maintains the Strata Precision Oncology Network, a collaborative entity aimed at promoting precision medicine initiatives. Formerly known as Strata Oncology Research, Inc., the company rebranded in 2016 and has been incorporated since 2015.

ArborMetrix, Inc. is a data analytics company that focuses on enhancing outcomes and measuring value within the healthcare sector. Founded in 2011 and based in Ann Arbor, Michigan, the company offers a suite of technology solutions that include data collection and integration, rigorous performance measurement, and analytics. ArborMetrix's platform provides essential tools such as EpisodeMetrix for cost analysis of healthcare episodes, RegistryMetrix for developing specialized clinical registries, and SurgicalMetrix for analyzing surgical performance. Their services aim to provide actionable insights that enable hospitals, health plans, physician organizations, and specialty societies to optimize financial performance, improve clinical outcomes, and support value-based reimbursement. Additionally, ArborMetrix offers solutions for clinical quality improvement, patient engagement, and post-market surveillance, serving a diverse range of clients within the U.S. healthcare landscape.

Pear Therapeutics, Inc. is a Boston-based commercial-stage healthcare company specializing in software-based digital therapeutics, also known as Prescription Digital Therapeutics (PDTs). Founded in 2013, the company develops clinically validated software solutions designed to treat a range of behavioral health disorders, including addiction, anxiety, depression, and chronic insomnia. Its suite of products includes mobile digital therapies that reward patients for engagement, and specific tools like reSET and reSET-O, aimed at treating substance use disorders. The company also offers Somryst, which provides neurobehavioral interventions for insomnia, and operates PearConnect, a patient services center that connects patients with advocates and resources, ensuring support throughout their treatment journey. Pear Therapeutics aims to enhance treatment outcomes by integrating digital therapies with pharmaceuticals and providing comprehensive support for patients, clinicians, and payors.

IntelliCyt Corporation, founded in 2006 and based in Albuquerque, New Mexico, specializes in developing high-throughput cell and bead-based screening solutions for the life sciences sector. The company utilizes proprietary technologies to create its iQue Screener platform, which integrates instruments, software, and reagents for multiplexed analysis of samples in liquid suspension. IntelliCyt's offerings include ForeCyt software for data visualization and analysis, as well as MultiCyt screening kits designed for use with iQue Screeners. These products cater to the needs of pharmaceutical and biotechnology companies, as well as medical centers, by significantly increasing the speed and efficiency of detecting and measuring cells and beads. The company addresses critical demands in drug discovery, antibody discovery, and in vitro toxicology, providing earlier and more relevant results while reducing costs. IntelliCyt operates as a subsidiary of Sartorius AG and is recognized for pioneering high-throughput screening technologies that enhance productivity in modern life sciences research.

Delphinus Medical Technologies, Inc. is a medical imaging company based in Plymouth, Michigan, with an additional office in Sunnyvale, California. Founded in 2009, the company specializes in developing and commercializing innovative breast cancer screening solutions. Its flagship product, SoftVue, employs a unique circular array transducer technology that utilizes ultrasound to provide three-dimensional and tomographic imaging of the entire breast. This system is designed to differentiate between benign and malignant masses, assess breast cancer risks, and monitor treatment, all while ensuring a comfortable experience for patients without the use of radiation. Delphinus serves hospitals and imaging clinics both in the United States and internationally, aiming to improve early detection and diagnosis of breast cancer.

Cardiac Dimensions, Inc. is a medical device company focused on developing innovative minimally invasive treatments for heart failure and associated cardiovascular issues. Founded in 2000 and headquartered in Kirkland, Washington, with additional operations in Sydney, Australia, and Offenbach, Germany, the company is known for its Carillon Mitral Contour System. This permanent implant is designed specifically for the treatment of functional mitral regurgitation, utilizing a catheter-based approach to reshape the mitral valve and effectively reduce regurgitation. By providing a non-surgical option for patients, Cardiac Dimensions aims to improve outcomes for those suffering from heart-related conditions.

My Health Direct, Inc. is a digital care coordination company that specializes in healthcare appointment scheduling and referral management. It provides a web-based platform that connects various healthcare entities, including hospitals, care management organizations, and community health collaboratives, facilitating the organization and booking of available healthcare appointments. This solution enhances actionable analytics, decision support, and workflow management to improve patient care and access. Founded in 2006 and initially known as Global Health Direct, the company is headquartered in Nashville, Tennessee. As of August 2019, My Health Direct operates as a subsidiary of Experian Health, Inc.

Cardiac Dimensions, Inc. is a medical device company focused on developing innovative minimally invasive treatments for heart failure and associated cardiovascular issues. Founded in 2000 and headquartered in Kirkland, Washington, with additional operations in Sydney, Australia, and Offenbach, Germany, the company is known for its Carillon Mitral Contour System. This permanent implant is designed specifically for the treatment of functional mitral regurgitation, utilizing a catheter-based approach to reshape the mitral valve and effectively reduce regurgitation. By providing a non-surgical option for patients, Cardiac Dimensions aims to improve outcomes for those suffering from heart-related conditions.

RethinkFirst is a company dedicated to empowering individuals and organizations by providing comprehensive behavioral health tools and support. Founded in 2008, RethinkFirst initially focused on scalable autism treatment training and caregiver support for underserved populations. Over the years, it expanded its offerings to include a full suite of special needs and behavior management solutions for the K-12 education sector, as well as employer and provider solutions for the broader autism and developmental disability community. Recognizing the widespread need for behavioral health support, RethinkFirst evolved its mission to address challenges faced by individuals with various behavioral health issues, including anxiety, depression, and substance abuse. The company now serves over 2,000 customers worldwide, including clinicians, educators, and employers, by offering cloud-based software platforms and evidence-based protocols that create supportive communities and help individuals reach their fullest potential. RethinkFirst's commitment to transforming the behavioral health landscape is evident in its goal to remove barriers to access and empower individuals with the necessary tools for healthier, happier lives.

NeuMoDx Molecular, Inc. is a molecular diagnostics company based in Ann Arbor, Michigan, that focuses on developing innovative solutions for molecular diagnostic testing in hospital and clinical reference laboratories. Established in 2012 and formerly known as Molecular Systems Corporation, NeuMoDx provides in-vitro testing tools designed to enhance the efficiency and cost-effectiveness of laboratory operations. The company's platform aims to increase the utilization of molecular diagnostics among medical providers, facilitating early disease identification and treatment. As of September 2020, NeuMoDx operates as a subsidiary of QIAGEN N.V.

Advance Medical, established in 1999, is a prominent global provider of telemedicine services, specializing in expert medical opinions delivered by board-certified physicians. The company offers employers and insurers worldwide access to top-quality medical advice via offices across the U.S., Europe, Asia, and South America. Its unique model ensures that every patient receives personalized attention through phone or video consultations, enabling accurate diagnoses, tailored treatment plans, and guidance on suitable healthcare facilities.

Adavium Medical is a medical equipment and diagnostics company based in São Paulo, Brazil, established in 2011. The company focuses on commercializing an innovative portfolio of medical devices and diagnostic products, representing leading international manufacturers. With a workforce of over 300 employees, Adavium Medical operates a fully-integrated commercial platform that adheres to high standards. It boasts the largest customer base in Brazil, serving more than 2,500 clients in both premium and long-tail segments of the medical equipment and diagnostics market. This extensive reach significantly surpasses that of typical distributors and multinational companies in the region, positioning Adavium Medical as a key player in a fragmented industry.

Delphinus Medical Technologies, Inc. is a medical imaging company based in Plymouth, Michigan, with an additional office in Sunnyvale, California. Founded in 2009, the company specializes in developing and commercializing innovative breast cancer screening solutions. Its flagship product, SoftVue, employs a unique circular array transducer technology that utilizes ultrasound to provide three-dimensional and tomographic imaging of the entire breast. This system is designed to differentiate between benign and malignant masses, assess breast cancer risks, and monitor treatment, all while ensuring a comfortable experience for patients without the use of radiation. Delphinus serves hospitals and imaging clinics both in the United States and internationally, aiming to improve early detection and diagnosis of breast cancer.

ArborMetrix, Inc. is a data analytics company that focuses on enhancing outcomes and measuring value within the healthcare sector. Founded in 2011 and based in Ann Arbor, Michigan, the company offers a suite of technology solutions that include data collection and integration, rigorous performance measurement, and analytics. ArborMetrix's platform provides essential tools such as EpisodeMetrix for cost analysis of healthcare episodes, RegistryMetrix for developing specialized clinical registries, and SurgicalMetrix for analyzing surgical performance. Their services aim to provide actionable insights that enable hospitals, health plans, physician organizations, and specialty societies to optimize financial performance, improve clinical outcomes, and support value-based reimbursement. Additionally, ArborMetrix offers solutions for clinical quality improvement, patient engagement, and post-market surveillance, serving a diverse range of clients within the U.S. healthcare landscape.

Fidelis SeniorCare, Inc., a managed care company, develops and administers health plans for assisted living residents in Michigan, North Carolina, and Texas. The company offers Medicare advantage special needs plans to cover the health needs of seniors living in nursing homes and assisted living communities; and individuals who require specialized healthcare. Its plans cover on-site primary care team visits, part D prescription drugs, monitoring and managing prescribed medications, transportation to the hospital or physician’s office, and skilled nursing services during a covered Medicare stay; preventive care, screening, vision/dental/hearing, and podiatry services; and emergency room, ambulance, and urgent care services. The company was founded in 2004 and is based in Schaumburg, Illinois.

IntelliCyt Corporation, founded in 2006 and based in Albuquerque, New Mexico, specializes in developing high-throughput cell and bead-based screening solutions for the life sciences sector. The company utilizes proprietary technologies to create its iQue Screener platform, which integrates instruments, software, and reagents for multiplexed analysis of samples in liquid suspension. IntelliCyt's offerings include ForeCyt software for data visualization and analysis, as well as MultiCyt screening kits designed for use with iQue Screeners. These products cater to the needs of pharmaceutical and biotechnology companies, as well as medical centers, by significantly increasing the speed and efficiency of detecting and measuring cells and beads. The company addresses critical demands in drug discovery, antibody discovery, and in vitro toxicology, providing earlier and more relevant results while reducing costs. IntelliCyt operates as a subsidiary of Sartorius AG and is recognized for pioneering high-throughput screening technologies that enhance productivity in modern life sciences research.

Esperion discovers and develops pharmaceutical products for the treatment of cardiovascular and metabolic diseases. Esperion intends to commercialize a novel class of drugs that focuses on a new treatment approach called "HDL Therapy," which is based on the Company's understanding of high-density lipoprotein, or HDL, function.

BAROnova, Inc. is a clinical-stage medical-device company founded in 2006 and headquartered in Goleta, California. The company specializes in developing non-surgical, non-pharmacologic devices aimed at inducing weight loss. Its primary product, the TransPyloric Shuttle, is a device that is inserted into the stomach through the mouth using a straightforward endoscopic procedure. This device is designed to enhance the sensation of fullness by causing the stomach to fill up faster and remain full longer, while also delaying gastric emptying. Through its innovative approach, BAROnova seeks to provide patients with effective tools for weight management without the need for surgery.

Tangent Medical Technologies, a development stage medical device company, was founded in Ann Arbor in 2009 based on technology exclusively licensed from the University of Michigan's Medical Innovation Center. The Company's mission is to improve infusion therapy for patients and healthcare workers with its proprietary, intravenous catheters and associated products. Tangent is led by an experienced, successful management team and the original inventors of the technology. The Company expects to begin generating commercial revenues from its lead product, the NovaCath™ Closed IV Catheter System, in 2012.

Tangent Medical Technologies, a development stage medical device company, was founded in Ann Arbor in 2009 based on technology exclusively licensed from the University of Michigan's Medical Innovation Center. The Company's mission is to improve infusion therapy for patients and healthcare workers with its proprietary, intravenous catheters and associated products. Tangent is led by an experienced, successful management team and the original inventors of the technology. The Company expects to begin generating commercial revenues from its lead product, the NovaCath™ Closed IV Catheter System, in 2012.

Sonitus Medical Inc. is a privately held medical device company based in San Mateo, California, focused on delivering innovative hearing solutions for patients with hearing challenges. The company specializes in bone conduction hearing devices and markets the SoundBite Hearing System, which is recognized as the world's first non-invasive and removable hearing solution that transmits sound through the teeth. This nearly invisible in-the-mouth hearing system is designed to address single-sided deafness and conductive hearing loss, providing a simple and non-surgical alternative for patients. The device is currently FDA cleared as a prosthetic for these specific conditions. Sonitus Medical aims to expand its technology to include treatments for mixed hearing loss and tinnitus, as well as applications in consumer and covert communications. Founded in 2006, Sonitus Medical is emerging as a leader in the field of hearing solutions.

Uptake Medical specializes in developing innovative medical technologies aimed at treating lung diseases. The company's flagship product, InterVapor™, is an endoscopic lung volume reduction therapy designed specifically for individuals with severe emphysema. This unique approach leverages the body’s natural healing processes and does not introduce any foreign materials into the lungs. Clinical studies have shown that InterVapor™ can lead to significant improvements in patients' breathing function, exercise capacity, and overall quality of life.

CerviLenz is a new, disposable device that measure vaginal cervical length during a speculum exam. Cervical length is a powerful predictor of preterm birth risk and influences patient management decisions. CerviLenz gives clinicians an immediate, reliable method for measuring the cervix at the point of care. CerviLenz is manufactured and distributed by Cervilenz Inc. headquartered in Chagrin Falls, Ohio.

Hicuity Health is a leading provider of high acuity telehealth services, delivering critical care solutions to over 115 hospitals across 30 states on a continuous basis. The company specializes in acute care telemedicine, offering services such as ICU programs and evidence-based protocols that utilize advanced tele-technology. By employing U.S. board-certified intensivists and operating multiple dedicated tele-care delivery centers, Hicuity Health enhances communication between physicians, nurses, patients, and onsite clinicians. This approach aims to improve patient outcomes and support hospitals in providing effective critical care.

Tangent Medical Technologies, a development stage medical device company, was founded in Ann Arbor in 2009 based on technology exclusively licensed from the University of Michigan's Medical Innovation Center. The Company's mission is to improve infusion therapy for patients and healthcare workers with its proprietary, intravenous catheters and associated products. Tangent is led by an experienced, successful management team and the original inventors of the technology. The Company expects to begin generating commercial revenues from its lead product, the NovaCath™ Closed IV Catheter System, in 2012.

CerviLenz is a new, disposable device that measure vaginal cervical length during a speculum exam. Cervical length is a powerful predictor of preterm birth risk and influences patient management decisions. CerviLenz gives clinicians an immediate, reliable method for measuring the cervix at the point of care. CerviLenz is manufactured and distributed by Cervilenz Inc. headquartered in Chagrin Falls, Ohio.

NxThera, founded in 2008 and headquartered in Maple Grove, Minnesota, specializes in the development of medical technologies for treating endourological conditions. The company's core technology involves convective water vapor energy, designed to deliver minimally invasive, thermal therapy for conditions such as benign prostatic hyperplasia (BPH), which affects over 32 million men in the U.S. As of April 30, 2018, NxThera operates as a subsidiary of Boston Scientific Corporation.

Wellfount Corp., established in 2006 and headquartered in Indianapolis, Indiana, specializes in providing pharmacy services to nursing facilities. The company offers a range of services including utilization and compliance reviews, multi-dose and compliance packaging, daily deliveries, intravenous therapy, and customized invoicing. Wellfount also provides EHR application integration and medical record services, along with medications and consulting services. Through its innovative technologies, the company aims to improve patient care quality and reduce costs by streamlining medication management processes in long-term care facilities.

My Health Direct, Inc. is a digital care coordination company that specializes in healthcare appointment scheduling and referral management. It provides a web-based platform that connects various healthcare entities, including hospitals, care management organizations, and community health collaboratives, facilitating the organization and booking of available healthcare appointments. This solution enhances actionable analytics, decision support, and workflow management to improve patient care and access. Founded in 2006 and initially known as Global Health Direct, the company is headquartered in Nashville, Tennessee. As of August 2019, My Health Direct operates as a subsidiary of Experian Health, Inc.

PathCentral is an Irvine, California-based company that offers a comprehensive, web-based enterprise software platform tailored for community pathologists. Developed by a team of pathologists and industry experts, PathCentral's platform integrates all facets of pathology practice operations, including specimen accessioning, laboratory workflow management, transcription, test send-outs, professional consultations, diagnosis, reporting, billing, and financial analysis. Additionally, the platform features a cloud-based professional network that facilitates online consultations among pathologists globally, enhancing collaboration and accessibility in the field of pathology.

Accuri Cytometers was founded to address a compelling need: life scientists love the rapid cell-by-cell analysis capability of flow cytometers, but too few have a flow cytometer in their lab. The barriers for most researchers include cost of the instrument, complexity of the software, effort required for maintenance, and the large amount of bench space required for the instrument. As a result, the company is looking to develop affordable and robust cytometers.

Delphinus Medical Technologies, Inc. is a medical imaging company based in Plymouth, Michigan, with an additional office in Sunnyvale, California. Founded in 2009, the company specializes in developing and commercializing innovative breast cancer screening solutions. Its flagship product, SoftVue, employs a unique circular array transducer technology that utilizes ultrasound to provide three-dimensional and tomographic imaging of the entire breast. This system is designed to differentiate between benign and malignant masses, assess breast cancer risks, and monitor treatment, all while ensuring a comfortable experience for patients without the use of radiation. Delphinus serves hospitals and imaging clinics both in the United States and internationally, aiming to improve early detection and diagnosis of breast cancer.

Uptake Medical specializes in developing innovative medical technologies aimed at treating lung diseases. The company's flagship product, InterVapor™, is an endoscopic lung volume reduction therapy designed specifically for individuals with severe emphysema. This unique approach leverages the body’s natural healing processes and does not introduce any foreign materials into the lungs. Clinical studies have shown that InterVapor™ can lead to significant improvements in patients' breathing function, exercise capacity, and overall quality of life.

CardioMEMS is a medical device company specializing in wireless monitoring solutions for severe chronic cardiovascular conditions. Their proprietary technology involves miniature sensors implanted via minimally invasive procedures, transmitting vital data like cardiac output, blood pressure, and heart rate to enhance patient management, particularly for heart failure, hypertension, and aneurysms.

CardioMEMS is a medical device company specializing in wireless monitoring solutions for severe chronic cardiovascular conditions. Their proprietary technology involves miniature sensors implanted via minimally invasive procedures, transmitting vital data like cardiac output, blood pressure, and heart rate to enhance patient management, particularly for heart failure, hypertension, and aneurysms.

Accuri Cytometers was founded to address a compelling need: life scientists love the rapid cell-by-cell analysis capability of flow cytometers, but too few have a flow cytometer in their lab. The barriers for most researchers include cost of the instrument, complexity of the software, effort required for maintenance, and the large amount of bench space required for the instrument. As a result, the company is looking to develop affordable and robust cytometers.

CerviLenz is a new, disposable device that measure vaginal cervical length during a speculum exam. Cervical length is a powerful predictor of preterm birth risk and influences patient management decisions. CerviLenz gives clinicians an immediate, reliable method for measuring the cervix at the point of care. CerviLenz is manufactured and distributed by Cervilenz Inc. headquartered in Chagrin Falls, Ohio.

BAROnova, Inc. is a clinical-stage medical-device company founded in 2006 and headquartered in Goleta, California. The company specializes in developing non-surgical, non-pharmacologic devices aimed at inducing weight loss. Its primary product, the TransPyloric Shuttle, is a device that is inserted into the stomach through the mouth using a straightforward endoscopic procedure. This device is designed to enhance the sensation of fullness by causing the stomach to fill up faster and remain full longer, while also delaying gastric emptying. Through its innovative approach, BAROnova seeks to provide patients with effective tools for weight management without the need for surgery.

HandyLab is a medical technology company that develops and manufactures molecular diagnostic assays and automation platforms The company’s proprietary platform reduces the time, cost, and complexity of testing while improving the quality of results. Using patented real-time microfluidic PCR technology, its products are positioned to decentralize nucleic acid testing. HandyLab was founded in 2000 and is based in Ann Arbor, Michigan. It was acquired by Becton, Dickinson and Company in 2009.

Accuri Cytometers was founded to address a compelling need: life scientists love the rapid cell-by-cell analysis capability of flow cytometers, but too few have a flow cytometer in their lab. The barriers for most researchers include cost of the instrument, complexity of the software, effort required for maintenance, and the large amount of bench space required for the instrument. As a result, the company is looking to develop affordable and robust cytometers.

Hicuity Health is a leading provider of high acuity telehealth services, delivering critical care solutions to over 115 hospitals across 30 states on a continuous basis. The company specializes in acute care telemedicine, offering services such as ICU programs and evidence-based protocols that utilize advanced tele-technology. By employing U.S. board-certified intensivists and operating multiple dedicated tele-care delivery centers, Hicuity Health enhances communication between physicians, nurses, patients, and onsite clinicians. This approach aims to improve patient outcomes and support hospitals in providing effective critical care.

Esperion discovers and develops pharmaceutical products for the treatment of cardiovascular and metabolic diseases. Esperion intends to commercialize a novel class of drugs that focuses on a new treatment approach called "HDL Therapy," which is based on the Company's understanding of high-density lipoprotein, or HDL, function.

Mirabilis Medical, Inc., established in 2004 and headquartered in Bothell, Washington, specializes in the design, development, manufacturing, distribution, installation, and servicing of ultrasound devices for non-invasive treatment of uterine fibroids. Their proprietary technology employs high-resolution ultrasound imaging for precise localization and non-invasive ablation of targeted tissue, eliminating the need for incisions or punctures.

KFx Medical specializes in the development and manufacturing of advanced soft tissue fixation implants specifically designed for orthopedic sports medicine. The company creates innovative products that facilitate tissue fixation, allowing for direct placement into bone, with or without sutures. These implants are utilized in various orthopedic surgical procedures, enabling surgeons to effectively reattach tissue in areas such as the shoulder, knee, foot, and ankle. KFx Medical collaborates with leading orthopedic surgeons to refine its technology and enhance surgical outcomes for patients.

Accuri Cytometers was founded to address a compelling need: life scientists love the rapid cell-by-cell analysis capability of flow cytometers, but too few have a flow cytometer in their lab. The barriers for most researchers include cost of the instrument, complexity of the software, effort required for maintenance, and the large amount of bench space required for the instrument. As a result, the company is looking to develop affordable and robust cytometers.

Inogen is a medical technology company specializing in oxygen therapy solutions for patients with chronic respiratory conditions. The company designs and manufactures portable oxygen concentrators, with its flagship product being the Inogen One system, which offers a lightweight and convenient alternative to traditional stationary oxygen concentrators and oxygen tanks. Inogen sells its products to home medical equipment providers and directly rents devices to patients, primarily generating its revenue in the United States. Additionally, the company distributes its products internationally through partnerships with large gas companies and home oxygen providers. Inogen's mission is to enhance the freedom and independence of oxygen therapy users by providing innovative and user-friendly products and services.

Uptake Medical specializes in developing innovative medical technologies aimed at treating lung diseases. The company's flagship product, InterVapor™, is an endoscopic lung volume reduction therapy designed specifically for individuals with severe emphysema. This unique approach leverages the body’s natural healing processes and does not introduce any foreign materials into the lungs. Clinical studies have shown that InterVapor™ can lead to significant improvements in patients' breathing function, exercise capacity, and overall quality of life.

Hicuity Health is a leading provider of high acuity telehealth services, delivering critical care solutions to over 115 hospitals across 30 states on a continuous basis. The company specializes in acute care telemedicine, offering services such as ICU programs and evidence-based protocols that utilize advanced tele-technology. By employing U.S. board-certified intensivists and operating multiple dedicated tele-care delivery centers, Hicuity Health enhances communication between physicians, nurses, patients, and onsite clinicians. This approach aims to improve patient outcomes and support hospitals in providing effective critical care.

BAROnova, Inc. is a clinical-stage medical-device company founded in 2006 and headquartered in Goleta, California. The company specializes in developing non-surgical, non-pharmacologic devices aimed at inducing weight loss. Its primary product, the TransPyloric Shuttle, is a device that is inserted into the stomach through the mouth using a straightforward endoscopic procedure. This device is designed to enhance the sensation of fullness by causing the stomach to fill up faster and remain full longer, while also delaying gastric emptying. Through its innovative approach, BAROnova seeks to provide patients with effective tools for weight management without the need for surgery.

KFx Medical specializes in the development and manufacturing of advanced soft tissue fixation implants specifically designed for orthopedic sports medicine. The company creates innovative products that facilitate tissue fixation, allowing for direct placement into bone, with or without sutures. These implants are utilized in various orthopedic surgical procedures, enabling surgeons to effectively reattach tissue in areas such as the shoulder, knee, foot, and ankle. KFx Medical collaborates with leading orthopedic surgeons to refine its technology and enhance surgical outcomes for patients.

Founded in 1998 by Dr. Victor Strecher, HealthMedia specializes in developing scalable behavior change interventions that emulate the effectiveness of health coaching without the need for a live coach. The company creates innovative programs tailored for health and wellness, disease management, behavioral health, and medication compliance. HealthMedia collaborates with pharmaceutical firms and medical device manufacturers to address various health challenges, including drug and alcohol addiction, mental illness, cardiovascular diseases, hypertension, and HIV/AIDS. Through its unique methodology and technology, HealthMedia delivers impactful outcomes comparable to traditional health coaching, making it a leader in the field of digital health solutions.