Arboretum Ventures

Avation Medical, Inc. is a company focused on developing a non-invasive closed-loop neuromodulation system aimed at treating overactive bladder in a home setting. Incorporated in 2016 and based in Columbus, Ohio, Avation Medical is at the forefront of innovation in wearable nerve stimulation systems. The company emphasizes empowering patients to manage their therapies, facilitating a more personalized approach to care. By leveraging advanced technologies, Avation Medical seeks to transform the neuromodulation market, enhancing the quality of care for individuals with chronic conditions through patient-centric solutions.

Delphinus Medical Technologies, Inc. is a medical imaging company based in Plymouth, Michigan, with an additional office in Sunnyvale, California. Founded in 2009, the company specializes in developing and commercializing innovative breast cancer screening solutions. Its flagship product, SoftVue, employs a unique circular array transducer technology that utilizes ultrasound to provide three-dimensional and tomographic imaging of the entire breast. This system is designed to differentiate between benign and malignant masses, assess breast cancer risks, and monitor treatment, all while ensuring a comfortable experience for patients without the use of radiation. Delphinus serves hospitals and imaging clinics both in the United States and internationally, aiming to improve early detection and diagnosis of breast cancer.

Navv Systems provides healthcare-focused indoor location technology with the NavvTrack platform. Integrated with Apple Maps, NavvTrack empowers hospitals with high-resolution indoor maps and tools to easily locate and manage staff, equipment, and resources. Developed at Henry Ford Innovations in Detroit, Michigan, NavvTrack is deployed in multiple U.S. hospitals, where it streamlines enterprise device management, helps coordinate team workflows and reduces operational costs.

Enumera Molecular is a life science tools company based in Ann Arbor, Michigan. It develops a scalable biomolecule assessment platform designed to enable lower-cost, rapid clinical liquid biopsy tests across various applications such as oncology and infectious disease testing.

Akadeum Life Sciences develops bioseparation products that facilitate the removal of target cells from biological samples using microscopic micro-bubbles. Its products enable medical practitioners to efficiently perform downstream testing and analysis.

Strata Oncology, Inc. is a precision oncology company focused on enhancing cancer care by facilitating access to precision medicine clinical trials and expediting drug approval processes. Based in Ann Arbor, Michigan, the company develops a comprehensive precision oncology platform that supports routine testing and efficient use of molecular data. Strata's offerings include The Strata Trial, a genomic testing program for systematic precision oncology implementation, and StrataNGS, a targeted assay for sequencing DNA and RNA from biopsies. Additionally, StrataPOINT integrates electronic medical record histories with molecular profiling to ensure eligible patients are tested and considered for trial enrollment. The company features a portfolio of pharma-sponsored therapeutic protocols, known as Strata Partnered Trials, aligned to specific biomarkers. Strata also operates The Strata Lab, a cancer sequencing facility, and maintains the Strata Precision Oncology Network, a collaborative entity aimed at promoting precision medicine initiatives. Formerly known as Strata Oncology Research, Inc., the company rebranded in 2016 and has been incorporated since 2015.

Navv Systems provides healthcare-focused indoor location technology with the NavvTrack platform. Integrated with Apple Maps, NavvTrack empowers hospitals with high-resolution indoor maps and tools to easily locate and manage staff, equipment, and resources. Developed at Henry Ford Innovations in Detroit, Michigan, NavvTrack is deployed in multiple U.S. hospitals, where it streamlines enterprise device management, helps coordinate team workflows and reduces operational costs.

Fifth Eye Inc. is a medical software company based in Ann Arbor, Michigan, specializing in real-time analytics for patient health monitoring. The company develops an innovative clinical decision support system that continuously analyzes a patient's hemodynamic status to predict the risk of instability. Its advanced software utilizes artificial intelligence to process real-time ECG data, enabling minute-to-minute assessments and providing healthcare professionals with early warnings of potential complications hours in advance of traditional methods. By offering continuous patient trajectory forecasts and historical trend analyses without requiring electronic health record inputs, Fifth Eye aims to enhance proactive patient care, improve clinical outcomes, and reduce hospital costs. Formerly known as Trove Analytics, Inc., Fifth Eye was incorporated in 2017 and rebranded in June 2018.

SonarMD, LLC, based in Elgin, Illinois, develops a subspecialty practice platform focused on care coordination for patients with chronic conditions, particularly those related to gut health. The company offers services designed to improve the management of complex chronic diseases that often require high-cost medications. By enhancing patient engagement and optimizing specialty pharmacy resources, SonarMD aims to keep patients healthier and reduce hospitalizations. Their approach integrates care management solutions that streamline the healthcare experience for both patients and clinical teams, ultimately fostering better health outcomes.

Strata Oncology, Inc. is a precision oncology company focused on enhancing cancer care by facilitating access to precision medicine clinical trials and expediting drug approval processes. Based in Ann Arbor, Michigan, the company develops a comprehensive precision oncology platform that supports routine testing and efficient use of molecular data. Strata's offerings include The Strata Trial, a genomic testing program for systematic precision oncology implementation, and StrataNGS, a targeted assay for sequencing DNA and RNA from biopsies. Additionally, StrataPOINT integrates electronic medical record histories with molecular profiling to ensure eligible patients are tested and considered for trial enrollment. The company features a portfolio of pharma-sponsored therapeutic protocols, known as Strata Partnered Trials, aligned to specific biomarkers. Strata also operates The Strata Lab, a cancer sequencing facility, and maintains the Strata Precision Oncology Network, a collaborative entity aimed at promoting precision medicine initiatives. Formerly known as Strata Oncology Research, Inc., the company rebranded in 2016 and has been incorporated since 2015.

Swift Biosciences Inc. is a biotechnology company based in Ann Arbor, Michigan, that specializes in the development and commercialization of next-generation sequencing (NGS) library preparation kits for genomics, translational, and clinical research. The company focuses on creating innovative molecular biology reagents, protocols, and diagnostic tools to enhance the efficiency and accuracy of genomic analysis. Its product offerings include various RNA and DNA library preparation kits, amplicon panels, hybridization capture kits, and specialized tools for cancer gene profiling and metagenomics. Swift Biosciences' technologies aim to streamline sample preparation processes and improve data quality from NGS instruments, supporting a wide range of applications such as circulating tumor cells and whole-genome sequencing. The company distributes its products through a network of distributors across Asia Pacific, Europe, the Middle East, and South America. Established in 2009, Swift Biosciences is committed to advancing molecular research and diagnostics.

Strata Oncology, Inc. is a precision oncology company focused on enhancing cancer care by facilitating access to precision medicine clinical trials and expediting drug approval processes. Based in Ann Arbor, Michigan, the company develops a comprehensive precision oncology platform that supports routine testing and efficient use of molecular data. Strata's offerings include The Strata Trial, a genomic testing program for systematic precision oncology implementation, and StrataNGS, a targeted assay for sequencing DNA and RNA from biopsies. Additionally, StrataPOINT integrates electronic medical record histories with molecular profiling to ensure eligible patients are tested and considered for trial enrollment. The company features a portfolio of pharma-sponsored therapeutic protocols, known as Strata Partnered Trials, aligned to specific biomarkers. Strata also operates The Strata Lab, a cancer sequencing facility, and maintains the Strata Precision Oncology Network, a collaborative entity aimed at promoting precision medicine initiatives. Formerly known as Strata Oncology Research, Inc., the company rebranded in 2016 and has been incorporated since 2015.

Founded in 2011 and headquartered in Ann Arbor, Michigan, ArborMetrix specializes in healthcare analytics. It provides data-driven insights to optimize clinical outcomes, financial performance, and stakeholder value for hospitals, health plans, physician groups, and medical societies. Its platform integrates and analyzes clinical data to measure the effectiveness of treatments, procedures, devices, and pharmaceuticals.

Delphinus Medical Technologies, Inc. is a medical imaging company based in Plymouth, Michigan, with an additional office in Sunnyvale, California. Founded in 2009, the company specializes in developing and commercializing innovative breast cancer screening solutions. Its flagship product, SoftVue, employs a unique circular array transducer technology that utilizes ultrasound to provide three-dimensional and tomographic imaging of the entire breast. This system is designed to differentiate between benign and malignant masses, assess breast cancer risks, and monitor treatment, all while ensuring a comfortable experience for patients without the use of radiation. Delphinus serves hospitals and imaging clinics both in the United States and internationally, aiming to improve early detection and diagnosis of breast cancer.

NeuMoDx Molecular, Inc. is a molecular diagnostics company based in Ann Arbor, Michigan, that focuses on developing innovative solutions for molecular diagnostic testing in hospital and clinical reference laboratories. Established in 2012 and formerly known as Molecular Systems Corporation, NeuMoDx provides in-vitro testing tools designed to enhance the efficiency and cost-effectiveness of laboratory operations. The company's platform aims to increase the utilization of molecular diagnostics among medical providers, facilitating early disease identification and treatment. As of September 2020, NeuMoDx operates as a subsidiary of QIAGEN N.V.

Delphinus Medical Technologies, Inc. is a medical imaging company based in Plymouth, Michigan, with an additional office in Sunnyvale, California. Founded in 2009, the company specializes in developing and commercializing innovative breast cancer screening solutions. Its flagship product, SoftVue, employs a unique circular array transducer technology that utilizes ultrasound to provide three-dimensional and tomographic imaging of the entire breast. This system is designed to differentiate between benign and malignant masses, assess breast cancer risks, and monitor treatment, all while ensuring a comfortable experience for patients without the use of radiation. Delphinus serves hospitals and imaging clinics both in the United States and internationally, aiming to improve early detection and diagnosis of breast cancer.

Founded in 2011 and headquartered in Ann Arbor, Michigan, ArborMetrix specializes in healthcare analytics. It provides data-driven insights to optimize clinical outcomes, financial performance, and stakeholder value for hospitals, health plans, physician groups, and medical societies. Its platform integrates and analyzes clinical data to measure the effectiveness of treatments, procedures, devices, and pharmaceuticals.

Fidelis SeniorCare, Inc., a managed care company, develops and administers health plans for assisted living residents in Michigan, North Carolina, and Texas. The company offers Medicare advantage special needs plans to cover the health needs of seniors living in nursing homes and assisted living communities; and individuals who require specialized healthcare. Its plans cover on-site primary care team visits, part D prescription drugs, monitoring and managing prescribed medications, transportation to the hospital or physician’s office, and skilled nursing services during a covered Medicare stay; preventive care, screening, vision/dental/hearing, and podiatry services; and emergency room, ambulance, and urgent care services. The company was founded in 2004 and is based in Schaumburg, Illinois.

Tangent Medical Technologies, a development stage medical device company, was founded in Ann Arbor in 2009 based on technology exclusively licensed from the University of Michigan's Medical Innovation Center. The Company's mission is to improve infusion therapy for patients and healthcare workers with its proprietary, intravenous catheters and associated products. Tangent is led by an experienced, successful management team and the original inventors of the technology. The Company expects to begin generating commercial revenues from its lead product, the NovaCath™ Closed IV Catheter System, in 2012.

Tangent Medical Technologies, a development stage medical device company, was founded in Ann Arbor in 2009 based on technology exclusively licensed from the University of Michigan's Medical Innovation Center. The Company's mission is to improve infusion therapy for patients and healthcare workers with its proprietary, intravenous catheters and associated products. Tangent is led by an experienced, successful management team and the original inventors of the technology. The Company expects to begin generating commercial revenues from its lead product, the NovaCath™ Closed IV Catheter System, in 2012.

CerviLenz is a new, disposable device that measure vaginal cervical length during a speculum exam. Cervical length is a powerful predictor of preterm birth risk and influences patient management decisions. CerviLenz gives clinicians an immediate, reliable method for measuring the cervix at the point of care. CerviLenz is manufactured and distributed by Cervilenz Inc. headquartered in Chagrin Falls, Ohio.

Hicuity Health is a technology-enabled clinical services provider specializing in high-acuity telehealth. It contracts to deliver care to more than 115 hospitals across 30 states on a 24/7/365 basis. The company combines remote patient monitoring, virtual care services, real-time clinical data integration, and access to specialized medical teams to support critical care delivery. It operates dedicated tele-care delivery centers and employs U.S. board-certified intensivists to support hospitals, families, and patients with improved oversight and care coordination, enabling scalable, around-the-clock critical care support for health systems.

Tangent Medical Technologies, a development stage medical device company, was founded in Ann Arbor in 2009 based on technology exclusively licensed from the University of Michigan's Medical Innovation Center. The Company's mission is to improve infusion therapy for patients and healthcare workers with its proprietary, intravenous catheters and associated products. Tangent is led by an experienced, successful management team and the original inventors of the technology. The Company expects to begin generating commercial revenues from its lead product, the NovaCath™ Closed IV Catheter System, in 2012.

CerviLenz is a new, disposable device that measure vaginal cervical length during a speculum exam. Cervical length is a powerful predictor of preterm birth risk and influences patient management decisions. CerviLenz gives clinicians an immediate, reliable method for measuring the cervix at the point of care. CerviLenz is manufactured and distributed by Cervilenz Inc. headquartered in Chagrin Falls, Ohio.

NxThera, founded in 2008 and headquartered in Maple Grove, Minnesota, specializes in the development of medical technologies for treating endourological conditions. The company's core technology involves convective water vapor energy, designed to deliver minimally invasive, thermal therapy for conditions such as benign prostatic hyperplasia (BPH), which affects over 32 million men in the U.S. As of April 30, 2018, NxThera operates as a subsidiary of Boston Scientific Corporation.

Delphinus Medical Technologies, Inc. is a medical imaging company based in Plymouth, Michigan, with an additional office in Sunnyvale, California. Founded in 2009, the company specializes in developing and commercializing innovative breast cancer screening solutions. Its flagship product, SoftVue, employs a unique circular array transducer technology that utilizes ultrasound to provide three-dimensional and tomographic imaging of the entire breast. This system is designed to differentiate between benign and malignant masses, assess breast cancer risks, and monitor treatment, all while ensuring a comfortable experience for patients without the use of radiation. Delphinus serves hospitals and imaging clinics both in the United States and internationally, aiming to improve early detection and diagnosis of breast cancer.

CerviLenz is a new, disposable device that measure vaginal cervical length during a speculum exam. Cervical length is a powerful predictor of preterm birth risk and influences patient management decisions. CerviLenz gives clinicians an immediate, reliable method for measuring the cervix at the point of care. CerviLenz is manufactured and distributed by Cervilenz Inc. headquartered in Chagrin Falls, Ohio.

HandyLab is a medical technology company that develops and manufactures molecular diagnostic assays and automation platforms The company’s proprietary platform reduces the time, cost, and complexity of testing while improving the quality of results. Using patented real-time microfluidic PCR technology, its products are positioned to decentralize nucleic acid testing. HandyLab was founded in 2000 and is based in Ann Arbor, Michigan. It was acquired by Becton, Dickinson and Company in 2009.

Hicuity Health is a technology-enabled clinical services provider specializing in high-acuity telehealth. It contracts to deliver care to more than 115 hospitals across 30 states on a 24/7/365 basis. The company combines remote patient monitoring, virtual care services, real-time clinical data integration, and access to specialized medical teams to support critical care delivery. It operates dedicated tele-care delivery centers and employs U.S. board-certified intensivists to support hospitals, families, and patients with improved oversight and care coordination, enabling scalable, around-the-clock critical care support for health systems.

Hicuity Health is a technology-enabled clinical services provider specializing in high-acuity telehealth. It contracts to deliver care to more than 115 hospitals across 30 states on a 24/7/365 basis. The company combines remote patient monitoring, virtual care services, real-time clinical data integration, and access to specialized medical teams to support critical care delivery. It operates dedicated tele-care delivery centers and employs U.S. board-certified intensivists to support hospitals, families, and patients with improved oversight and care coordination, enabling scalable, around-the-clock critical care support for health systems.

Asterand Bioscience is a leading global provider of high-quality human tissue and human tissue-based research solutions, primarily aimed at drug discovery scientists. Established in 2006 through the merger of Asterand, a human tissue biorepository, and Pharmagene, a drug discovery company, Asterand has a strong heritage in human tissue procurement and characterization. The company focuses on accelerating the identification and validation of drug targets while enhancing the selection of drug candidates to increase the likelihood of clinical success. With offices in Detroit, Michigan, and Royston, United Kingdom, Asterand serves pharmaceutical, biotechnology, and diagnostic companies, as well as academic institutions, offering comprehensive research services that span from target identification to compound evaluation and drug safety.