Arkin Holdings

Arkin Holdings is a venture capital firm based in Israel that concentrates on healthcare technologies, including pharmaceuticals, biotechnology, dermatology, medical devices, and digital health. The firm provides strategic support to portfolio companies and seeks to accelerate value creation through its industry expertise and hands-on partnership. Operating through multiple investment arms, Arkin Holdings maintains a diverse healthcare portfolio and collaborates with leading Israeli institutional investors. The group also includes Arkin Digital Health, a unit that finances and guides early-stage software-based healthcare ventures and draws on cross-border exposure in the United States and Israel to scale innovative solutions. Through its focus on health tech across life sciences and digital health, Arkin Holdings aims to advance breakthroughs that improve patient care and medical outcomes.

Itai Arkin

Investment Manager

Sam Cronin

Investment Manager and Principal

Alon Lazarus

Biotech Investment Manager

Pini Orbach

Managing Partner

Nadav Shimoni MD

Head of Digital Health and Managing Director

57 past transactions

Newleos Therapeutics

Series A in 2025
Newleos Therapeutics is a stealth-mode biotechnology company focused on developing safer and more effective treatments for neuropsychiatric disorders, aiming to improve mental health outcomes.

Auron Therapeutics

Series B in 2025
Auron Therapeutics is a biotechnology company focused on cancer therapy development that seeks to change the paradigm from tumor cell killing to differentiation therapy, aiming to transform malignant cells into normal functioning cells by reactivating endogenous cellular programs. The company uses platforms that integrate large-omic datasets and miniaturized high-throughput flow cytometry to rapidly identify and validate multiple targets and drugs in primary human patient samples. This approach is designed to advance therapeutic candidates for cancer across areas of unmet medical need and to support the development of transformative medicines. Auron Therapeutics was founded in 2018 and is based in Wellesley, Massachusetts.

Revisto

Seed Round in 2024
Revisto is a technology company that specializes in streamlining the medical, legal, and regulatory review process for pharmaceutical marketing materials. Utilizing AI, their platform accelerates the release time of these materials, reduces costs, and mitigates compliance risks. It automates the review process, provides content recommendations based on historical data, and ensures adherence to regulatory requirements.

Phytolon

Venture Round in 2024
Phytolon Ltd is a company based in Misgav, Israel, specializing in the development of natural food colorants. Founded in 2000, Phytolon utilizes a novel fermentation technology that employs baker's yeast cells as biofactories to produce high-quality, plant-based food colors. This innovative approach offers a healthy alternative to synthetic food dyes, providing food manufacturers with safe, cost-effective, and stable all-natural color solutions. The company's mission is to leverage scientific advancements to promote human health and environmental sustainability in the food industry.

Bluejay Therapeutics

Series C in 2024
Bluejay Therapeutics is a private biopharmaceutical company focused on developing curative treatments for infectious and liver diseases. Its initial program targets chronic hepatitis B, a widespread infection with unmet medical need, using two approaches: fully human IgG1 monoclonal antibodies against hepatitis B surface antigen and oral small-molecule inhibitors of HBsAg. The aim is to reduce viral surface antigen and restore adaptive immunity, potentially achieving a functional cure for HBV and enabling patients to regain immune control of infection. The company’s work also contemplates extending its approach to other viral liver diseases, including chronic hepatitis D.

Honeycomb

Series B in 2024
Honeycomb, formerly known as Agilius, operates an insurance technology platform that specializes in real estate insurance services. Founded in 2019 and based in San Francisco, California, the company offers a streamlined online process for homeowners associations, property managers, developers, and building owners to purchase master insurance policies for condominium and apartment buildings in under three minutes. By leveraging advanced technologies such as aerial photography, computer vision, artificial intelligence, and machine learning, Honeycomb eliminates the need for on-site inspections, allowing users to obtain instant, hassle-free quotes and manage their policies efficiently. This innovative approach aims to bring simplicity and transparency to the real estate insurance market, providing significant cost savings for its clients.

Reunion Neuroscience

Series A in 2024
Reunion Neuroscience is a clinical-stage pharmaceutical company focused on developing therapeutic solutions for underserved mental health conditions. Its lead asset, RE104, is a proprietary psychedelic compound being developed as a potential fast-acting and durable antidepressant for patients suffering from postpartum depression and other mental health conditions.

Nocion Therapeutics

Series B in 2024
Nocion Therapeutics is a biopharmaceutical company developing novel therapies called 'nocions' that selectively target actively firing nociceptors to provide relief for serious conditions such as cough, itch, pain, and inflammation.

Siftwell Analytics

Seed Round in 2024
Siftwell operates as a predictive analytics company in the healthcare sector, utilizing artificial intelligence and machine learning to analyze extensive datasets, including health plan data, claims, and social determinants of health. The company focuses on identifying members at high risk for rising costs, declining health, and potential churn. By enhancing data-driven decision-making, Siftwell enables clients to improve member health outcomes, reduce healthcare costs, and enhance quality metrics, ultimately fostering greater member retention. Their unique expertise combines technology with managed care, allowing for an effective approach to solving complex challenges in the healthcare industry.

NextPoint Therapeutics

Series B in 2024
NextPoint Therapeutics is a clinical-stage biotechnology company that develops therapeutics to treat cancer patients. The company offers immunotherapies for a validated checkpoint axis that is independent of PD-1/L1 and modulates both adaptive and innate immune systems to find and destroy cancer cells. It advances therapeutic approaches utilizing the unique upregulation of HHLA2 in cancer as an anchor for tumor-targeting therapeutic modalities.

HI-Bio

Series B in 2024
Human Immunology Biosciences is a biotechnology company dedicated to developing precision therapies for immune-mediated diseases, particularly autoimmune and inflammatory conditions. The company is known for its lead product, felzartamab, a fully human anti-CD38 monoclonal antibody that targets and depletes CD38+ cells, including plasma and natural killer cells. This mechanism has shown promise in improving clinical outcomes across a range of immune-mediated disorders. By focusing on transformative biotechnology-based treatments, Human Immunology Biosciences aims to enhance the quality of life for patients suffering from these challenging conditions.

Eleos Health

Series B in 2023
Eleos Health offers automated healthcare technology solutions. Its AI-powered Speech-to-Insights system aids clinicians in making decisions swiftly, ensuring personalized, efficient, and cost-effective patient care.

MadeRight

Seed Round in 2023
MadeRight is a company based in San Mateo, California, engaged in the manufacturing and sale of apparel, jewelry, and accessories, both domestically and internationally. Its product range includes a variety of clothing items such as tops, bottoms, jackets, outerwear, tees, sweaters, underwear, suits, shirts, jeans, and leather shoes, as well as cotton woven fabrics and specialty textiles. In addition to its apparel business, MadeRight specializes in sustainable packaging solutions through a natural additive derived from fungi grown on industrial waste. This innovative additive enhances the performance of bio-plastics, making them more scalable, affordable, and degradable. It improves the physical and functional properties of packaging materials, including attributes such as anti-microbial and heat resistance.

Percepto

Series C in 2023
Percepto is a developer of autonomous drone technology for inspection and surveillance. The company is at the forefront of redefining how industrial sites and critical infrastructure are holistically inspected and monitored, harnessing remote robotics to autonomously collect, aggregate, and analyze visual data. Leveraging its experience with Percepto Sparrow, the first deployed drone-in-a-box solution on the market, Percepto introduced Percepto AIM (Autonomous Inspection and Monitoring), the first end-to-end autonomous inspection and monitoring platform. Percepto AIM empowers the remote operation center of the future to assess risk, minimize downtime, drive efficiency, increase safety, and reduce operational costs.

Revamp Medical

Series A in 2023
Revamp Medical, founded in 2016, is dedicated to addressing the critical unmet needs of patients suffering from acute heart failure. With over one million annual admissions in the United States and associated costs exceeding $65 billion, the company aims to provide an innovative solution through its patented temporary catheter, Doraya™. This device regulates vascular hemodynamics, particularly for patients experiencing diuretic resistance, by managing preload and reducing central venous pressure. This functionality enhances diuretic efficacy and facilitates progressive decongestion, thereby allowing cardiologists to effectively manage key hemodynamic parameters. Revamp Medical is supported by a skilled team with extensive experience in the medical technology sector, positioning the company to make a significant impact in the treatment of acute heart failure.

Pigmentum

Seed Round in 2023
Pigmentum is an ag-tech company developing a molecular platform that enables external gene activation in plants.

Nest Genomics (YC W22)

Seed Round in 2023
Nest Genomics is a lab-agnostic, comprehensive software solution for implementing genomic programs at scale.

Entact Bio

Series A in 2022
Entact Bio is a biotechnology company that is in the preclinical stages of developing medications to improve protein function. It was founded by a team with deep roots in deubiquitinase (DUB) biochemistry, chemical biology, disease biology, and small-molecule drug development. The company's proprietary EncompassTM platform was designed to create enhancement-targeting chimeric (ENTACTM) medicines. ENTACs take advantage of DUBs' ability to regulate proteins.

Validic

Venture Round in 2022
Validic, Inc. is a technology company specializing in a cloud-based platform that collects and manages mobile health data from various internet-enabled applications and devices. Founded in 2010 and based in Durham, North Carolina, Validic connects healthcare organizations with over 400 clinical and consumer devices, allowing for the integration of patient-recorded data into clinical workflows. Its primary offerings include Validic Solution, which links digital health data to healthcare providers; Validic Connect, which facilitates access to a broader range of clinical and consumer applications; and Validic Mobile, designed for data collection from health apps and in-home devices. The company serves a diverse clientele, including wellness companies, healthcare providers, pharmaceuticals, and health plans, with the goal of enhancing the quality of human life through actionable health data.

Photys Therapeutics

Series A in 2022
Photys Therapeutics is a biopharmaceutical company focused on developing bifunctional small molecules that provide precise control over protein post-translational modifications. This innovative platform allows for the restoration of protein function, repair of cellular signaling pathways, and enhancement of the body's natural disease-fighting abilities. Co-founded by prominent chemist Amit Choudhary from the Broad Institute and the Longwood Fund, Photys is supported by a scientific advisory board that includes renowned experts from institutions such as MIT, Salk Institute, and Berkeley. The company's unique approach aims to advance therapeutic options in the healthcare industry, particularly by targeting kinases and potentially phosphatases, to address various diseases effectively.

Welcome Homes

Series A in 2022
Welcome Homes is an innovative online platform streamlining the new home construction journey. It enables buyers to select land, customize designs, secure financing, and oversee construction seamlessly and transparently.

Bluejay Therapeutics

Series B in 2022
Bluejay Therapeutics is a private biopharmaceutical company focused on developing curative treatments for infectious and liver diseases. Its initial program targets chronic hepatitis B, a widespread infection with unmet medical need, using two approaches: fully human IgG1 monoclonal antibodies against hepatitis B surface antigen and oral small-molecule inhibitors of HBsAg. The aim is to reduce viral surface antigen and restore adaptive immunity, potentially achieving a functional cure for HBV and enabling patients to regain immune control of infection. The company’s work also contemplates extending its approach to other viral liver diseases, including chronic hepatitis D.

Virility Medical

Venture Round in 2022
Virility Medical is focused on developing an innovative intimate skin patch aimed at addressing premature ejaculation, a common male sexual dysfunction. The patch is equipped with an electronic module that generates neuromuscular electrical stimulation, which is delivered transcutaneously to surrounding muscles. This technology enables users to effectively delay the onset of premature ejaculation, providing a discreet and non-invasive solution for men seeking to enhance their sexual performance.

Auron Therapeutics

Series A in 2022
Auron Therapeutics is a biotechnology company focused on cancer therapy development that seeks to change the paradigm from tumor cell killing to differentiation therapy, aiming to transform malignant cells into normal functioning cells by reactivating endogenous cellular programs. The company uses platforms that integrate large-omic datasets and miniaturized high-throughput flow cytometry to rapidly identify and validate multiple targets and drugs in primary human patient samples. This approach is designed to advance therapeutic candidates for cancer across areas of unmet medical need and to support the development of transformative medicines. Auron Therapeutics was founded in 2018 and is based in Wellesley, Massachusetts.

Phytolon

Series A in 2022
Phytolon Ltd is a company based in Misgav, Israel, specializing in the development of natural food colorants. Founded in 2000, Phytolon utilizes a novel fermentation technology that employs baker's yeast cells as biofactories to produce high-quality, plant-based food colors. This innovative approach offers a healthy alternative to synthetic food dyes, providing food manufacturers with safe, cost-effective, and stable all-natural color solutions. The company's mission is to leverage scientific advancements to promote human health and environmental sustainability in the food industry.

Rhino Federated Computing

Venture Round in 2022
The value of connecting disparate datasets is immense, yet much of this potential remains untapped. Imagine the transformative possibilities: pharmaceutical companies sharing data to design better drugs and evaluate their real-world value, hospitals and HMOs diagnosing rare diseases faster, or financial institutions collaborating to combat financial crime. Rhino Federated Computing makes this vision a reality. Our federated computing platform, powered by advanced edge-computing and federated learning technologies, enables organizations to train and deploy AI models on massive, distributed datasets—without sharing sensitive information or compromising data privacy and sovereignty. This breakthrough approach was pioneered by our co-founder and CEO, Dr. Ittai Dayan, a recognized leader in the field whose work includes a landmark Nature Medicine publication in 2021.

Fu-Gen

Private Equity Round in 2022
Fu-Gen is an independent power producer and renewable energy investor focused on developing and managing a network of renewable energy projects. The company specializes in creating greenfield initiatives and investing in various stages of project development, from pre-permit to operational phases, primarily in wind and solar energy. By building a diverse portfolio that includes solar, wind, and energy storage projects, Fu-Gen aims to optimize renewable energy assets and support the transition to a low carbon economy in Europe. The firm is committed to delivering sustainable returns to its investors while contributing to the growth of the renewable energy sector.

Eleos Health

Series A in 2022
Eleos Health offers automated healthcare technology solutions. Its AI-powered Speech-to-Insights system aids clinicians in making decisions swiftly, ensuring personalized, efficient, and cost-effective patient care.

Mindspace

Venture Round in 2021
Founded in 2013, Mindspace specializes in providing high-end flexible workspace solutions. It offers open spaces, private offices, meeting rooms, and event spaces, accommodating entrepreneurs, freelancers, startups, and enterprises across Europe and the US.

Eleos Health

Seed Round in 2021
Eleos Health offers automated healthcare technology solutions. Its AI-powered Speech-to-Insights system aids clinicians in making decisions swiftly, ensuring personalized, efficient, and cost-effective patient care.

Lendbuzz

Series C in 2021
Lendbuzz, Inc. is a Boston-based company that operates an innovative car financing platform aimed at individuals with limited or no credit history, such as international students, foreign professionals, and expatriates. Founded in 2015, Lendbuzz uses machine learning algorithms and proprietary technology to assess the creditworthiness of consumers who are typically underserved by traditional financial institutions. By evaluating background information, including employment and educational history, the platform provides tailored car loans and financing solutions with favorable terms and low-interest rates. Lendbuzz partners with auto dealerships to enhance their offerings, allowing them to serve a more diverse clientele and close additional business opportunities. The company emphasizes a streamlined documentation process, making it easier for clients to access and manage their loans.

Laguna Health

Seed Round in 2021
Laguna Health employs AI-powered conversational intelligence combined with clinical protocols to assist care managers. This enables more efficient and consistent care responses, improving patient outcomes while enhancing productivity for care teams.

Edocate

Seed Round in 2021
Edocate develops a medical simulation platform focused on chronic disease management. Its platform enables healthcare professionals to engage with virtual patient cases across various therapeutic areas, providing insights into decision-making processes, clinical gaps, and prescription patterns.

MedMinder Systems

Private Equity Round in 2021
MedMinder Systems, Inc. is a company that specializes in developing innovative solutions for medication management and adherence support. Founded in 2007 and headquartered in Needham, Massachusetts, the company offers a range of products including automatic pill dispensers that remind users of their medication schedules through visual and auditory alerts, as well as notifications sent to caregivers and pharmacists. MedMinder's offerings include various types of pill dispensers, locked dispensers, medical alert products, and pre-filled medication trays. The company serves a diverse customer base across several states, including Massachusetts, New York, Florida, and others. Through its services, MedMinder aims to simplify the process of taking medications, thereby improving adherence and enhancing patient care.

Rhino Federated Computing

Seed Round in 2021
The value of connecting disparate datasets is immense, yet much of this potential remains untapped. Imagine the transformative possibilities: pharmaceutical companies sharing data to design better drugs and evaluate their real-world value, hospitals and HMOs diagnosing rare diseases faster, or financial institutions collaborating to combat financial crime. Rhino Federated Computing makes this vision a reality. Our federated computing platform, powered by advanced edge-computing and federated learning technologies, enables organizations to train and deploy AI models on massive, distributed datasets—without sharing sensitive information or compromising data privacy and sovereignty. This breakthrough approach was pioneered by our co-founder and CEO, Dr. Ittai Dayan, a recognized leader in the field whose work includes a landmark Nature Medicine publication in 2021.

Auron Therapeutics

Seed Round in 2021
Auron Therapeutics is a biotechnology company focused on cancer therapy development that seeks to change the paradigm from tumor cell killing to differentiation therapy, aiming to transform malignant cells into normal functioning cells by reactivating endogenous cellular programs. The company uses platforms that integrate large-omic datasets and miniaturized high-throughput flow cytometry to rapidly identify and validate multiple targets and drugs in primary human patient samples. This approach is designed to advance therapeutic candidates for cancer across areas of unmet medical need and to support the development of transformative medicines. Auron Therapeutics was founded in 2018 and is based in Wellesley, Massachusetts.

BioSight

Series C in 2020
BioSight Ltd., established in 1999 and headquartered in Lod, Israel, is a biopharmaceutical company specializing in the development of innovative cancer-targeted pro-drugs. It focuses on creating non-toxic conjugates like its cytarabine-asparagine conjugate for treating acute myeloid leukemia patients worldwide. BioSight's proprietary technology, S2DOT™, enables targeted drug release inside cancer cells, minimizing systemic toxicity compared to conventional chemotherapy treatments.

Percepto

Series B in 2020
Percepto is a developer of autonomous drone technology for inspection and surveillance. The company is at the forefront of redefining how industrial sites and critical infrastructure are holistically inspected and monitored, harnessing remote robotics to autonomously collect, aggregate, and analyze visual data. Leveraging its experience with Percepto Sparrow, the first deployed drone-in-a-box solution on the market, Percepto introduced Percepto AIM (Autonomous Inspection and Monitoring), the first end-to-end autonomous inspection and monitoring platform. Percepto AIM empowers the remote operation center of the future to assess risk, minimize downtime, drive efficiency, increase safety, and reduce operational costs.

Pixellot

Series C in 2020
Pixellot specializes in automated video production solutions for amateur and semi-professional sports. Its patented technology uses unmanned multi-camera systems to cover entire fields, generating dynamic coverage and highlights. With over 2,000 systems sold worldwide, Pixellot streams live hours monthly to fans, players, and coaches across various platforms. Partners include ESPN, Sporttotal.tv, STATS, and leading clubs like Bayern Munich.

Redpin Therapeutics

Series A in 2020
Redpin Therapeutics, Inc. is a preclinical stage gene therapy company founded in 2017 and based in New York, New York. The company specializes in developing a proprietary chemogenetics platform for targeted cell therapies aimed at addressing intractable diseases of the nervous system. Redpin's innovative approach utilizes ion channels as neuromodulation tools, allowing for selective activation or inhibition of disease-causing neurons while preserving normal functioning cells. By controlling these neuronal circuits, Redpin enables physicians to precisely target dysfunctional neural activity associated with specific conditions. The company's technology integrates principles from synthetic biology, gene therapy, and traditional pharmacotherapy to advance its mission of addressing complex neurological disorders.

BioSight

Series C in 2020
BioSight Ltd., established in 1999 and headquartered in Lod, Israel, is a biopharmaceutical company specializing in the development of innovative cancer-targeted pro-drugs. It focuses on creating non-toxic conjugates like its cytarabine-asparagine conjugate for treating acute myeloid leukemia patients worldwide. BioSight's proprietary technology, S2DOT™, enables targeted drug release inside cancer cells, minimizing systemic toxicity compared to conventional chemotherapy treatments.

Keros Therapeutics

Series C in 2020
Keros Therapeutics, Inc. is a clinical-stage biopharmaceutical company based in Lexington, Massachusetts, dedicated to the discovery, development, and commercialization of innovative treatments for hematological and musculoskeletal disorders with significant unmet medical needs. The company's lead product candidate, KER-050, targets low blood cell counts, or cytopenias, including anemia and thrombocytopenia in patients with myelodysplastic syndromes and myelofibrosis. Additionally, Keros is developing KER-047, a small molecule aimed at treating anemia and fibrodysplasia ossificans progressiva, which is currently in Phase 1 clinical trials. Another candidate, KER-012, is being explored for its potential in treating bone loss disorders such as osteoporosis and osteogenesis imperfecta, as well as pulmonary arterial hypertension. Keros Therapeutics emphasizes understanding the role of the Transforming Growth Factor-Beta family of proteins, which are crucial for the regulation of blood cell production and the maintenance of muscle and bone health.

Metabomed

Series B in 2019
Metabomed is a drug discovery company focused on developing treatments for cancer by targeting the unique metabolic pathways of cancer cells. Its proprietary platform leverages computational biology, genomics, and metabolomics to identify specific metabolic alterations that support cancer growth. By creating small molecules that specifically target these reprogrammed metabolic processes, Metabomed aims to halt tumor progression while minimizing harm to surrounding healthy tissues. This innovative approach allows for quicker initiation of treatment and increases the likelihood of successful patient outcomes.

Werewolf Therapeutics

Series A in 2019
Werewolf Therapeutics, Inc. is a biotechnology company based in Cambridge, Massachusetts, focused on developing innovative receptor agonists for cancer immunotherapy. Founded in 2017, the company is dedicated to creating therapeutics that stimulate the body’s immune system to combat cancer. Utilizing its proprietary PREDATOR platform, Werewolf designs conditionally activated molecules known as INDUKINE, which are engineered to remain inactive in peripheral tissues while selectively activating within the tumor microenvironment. This approach aims to overcome the limitations of traditional proinflammatory immune therapies, enhancing both adaptive and innate immunity to improve cancer treatment outcomes.

Pi Therapeutics

Series B in 2019
Pi Therapeutics is a discovery-stage biopharmaceutical company aiming to develop a novel cancer drug. The company is financed by a syndicate of Takeda Pharmaceutical Company through its venture group Takeda Ventures Inc., Johnson & Johnson Innovation – JJDC, OrbiMed Israel Partners, Pontifax, and the Israel Innovation Authority, and has operated since March 2015 in the FutuRx biotech accelerator in Ness Ziona, Israel. The company’s mission is to develop novel first-in-class drugs directed against the ubiquitin-proteasome system (UPS), mainly for treatment of cancer.

Keros Therapeutics

Series B in 2019
Keros Therapeutics, Inc. is a clinical-stage biopharmaceutical company based in Lexington, Massachusetts, dedicated to the discovery, development, and commercialization of innovative treatments for hematological and musculoskeletal disorders with significant unmet medical needs. The company's lead product candidate, KER-050, targets low blood cell counts, or cytopenias, including anemia and thrombocytopenia in patients with myelodysplastic syndromes and myelofibrosis. Additionally, Keros is developing KER-047, a small molecule aimed at treating anemia and fibrodysplasia ossificans progressiva, which is currently in Phase 1 clinical trials. Another candidate, KER-012, is being explored for its potential in treating bone loss disorders such as osteoporosis and osteogenesis imperfecta, as well as pulmonary arterial hypertension. Keros Therapeutics emphasizes understanding the role of the Transforming Growth Factor-Beta family of proteins, which are crucial for the regulation of blood cell production and the maintenance of muscle and bone health.

Keros Therapeutics

Series A in 2017
Keros Therapeutics, Inc. is a clinical-stage biopharmaceutical company based in Lexington, Massachusetts, dedicated to the discovery, development, and commercialization of innovative treatments for hematological and musculoskeletal disorders with significant unmet medical needs. The company's lead product candidate, KER-050, targets low blood cell counts, or cytopenias, including anemia and thrombocytopenia in patients with myelodysplastic syndromes and myelofibrosis. Additionally, Keros is developing KER-047, a small molecule aimed at treating anemia and fibrodysplasia ossificans progressiva, which is currently in Phase 1 clinical trials. Another candidate, KER-012, is being explored for its potential in treating bone loss disorders such as osteoporosis and osteogenesis imperfecta, as well as pulmonary arterial hypertension. Keros Therapeutics emphasizes understanding the role of the Transforming Growth Factor-Beta family of proteins, which are crucial for the regulation of blood cell production and the maintenance of muscle and bone health.

Lendbuzz

Funding Round in 2017
Lendbuzz, Inc. is a Boston-based company that operates an innovative car financing platform aimed at individuals with limited or no credit history, such as international students, foreign professionals, and expatriates. Founded in 2015, Lendbuzz uses machine learning algorithms and proprietary technology to assess the creditworthiness of consumers who are typically underserved by traditional financial institutions. By evaluating background information, including employment and educational history, the platform provides tailored car loans and financing solutions with favorable terms and low-interest rates. Lendbuzz partners with auto dealerships to enhance their offerings, allowing them to serve a more diverse clientele and close additional business opportunities. The company emphasizes a streamlined documentation process, making it easier for clients to access and manage their loans.

ARTSaVIT

Series A in 2017
ARTSaVIT is a biopharmaceuticals company developing a cancer drug.

Digma Medical

Series B in 2016
Digma Medical is a clinical stage medical device company focused on innovative treatments for Type-2 Diabetes and related metabolic disorders, including NASH. Founded in 2013, the company is developing the DiaGone™, a disposable endoscopic device that employs advanced laser technology to target the duodenum, the first section of the small intestine. This device is designed to address insulin resistance, the core issue in these diseases. The Duodenal Glycemic Control™ procedure, which lasts approximately 30 minutes, allows gastroenterologists to utilize the DiaGone™ to enhance the body's natural ability to regulate glucose levels. This approach aims to offer patients the potential for long-term remission from Type-2 Diabetes and improve overall health outcomes.

Oncorus

Series A in 2016
Oncorus, Inc. is a clinical-stage biopharmaceutical company based in Cambridge, Massachusetts, dedicated to developing innovative viral immunotherapies for cancer treatment. The company's lead product candidate, ONCR-177, utilizes an oncolytic herpes simplex virus type 1 platform and is currently undergoing Phase I clinical trials to assess its efficacy against various cancers. In addition to ONCR-177, Oncorus is advancing its ONCR-GBM program aimed at treating brain cancer, along with synthetic viral immunotherapies derived from Coxsackievirus A21 and Seneca Valley Virus. The company has established a clinical trial collaboration with MSD International GmbH to evaluate the safety and tolerability of ONCR-177 in combination with Merck’s KEYTRUDA immunotherapy. Founded in 2015, Oncorus is committed to improving patient outcomes and has pledged to contribute a portion of its product sales to support cancer research and care in developing regions.

BioSight

Venture Round in 2016
BioSight Ltd., established in 1999 and headquartered in Lod, Israel, is a biopharmaceutical company specializing in the development of innovative cancer-targeted pro-drugs. It focuses on creating non-toxic conjugates like its cytarabine-asparagine conjugate for treating acute myeloid leukemia patients worldwide. BioSight's proprietary technology, S2DOT™, enables targeted drug release inside cancer cells, minimizing systemic toxicity compared to conventional chemotherapy treatments.

Metabomed

Series A in 2016
Metabomed is a drug discovery company focused on developing treatments for cancer by targeting the unique metabolic pathways of cancer cells. Its proprietary platform leverages computational biology, genomics, and metabolomics to identify specific metabolic alterations that support cancer growth. By creating small molecules that specifically target these reprogrammed metabolic processes, Metabomed aims to halt tumor progression while minimizing harm to surrounding healthy tissues. This innovative approach allows for quicker initiation of treatment and increases the likelihood of successful patient outcomes.

Sol-Gel Technologies

Acquisition in 2014
Sol-Gel Technologies is a clinical-stage specialty pharmaceutical company focused on developing and commercializing topical dermatological drug products using its proprietary microencapsulation delivery system. Its pipeline includes product candidates for various skin conditions such as acne, rosacea, psoriasis, and rare keratosis-related indications.

Quiet Therapeutics

Seed Round in 2013
Quiet Therapeutics Ltd. is a biotechnology company based in Ness Ziona, Israel, focused on discovering and developing innovative cancer therapies. Founded in 2009, the company employs its proprietary GAGomer technology, which includes RNA therapeutics and small molecule drugs, to specifically target tumor cells. This unique nanoparticle-based delivery system enhances the targeting capability of therapeutic agents, allowing for the effective treatment of cancer and inflammation. By concentrating on cell components that are challenging for conventional therapies to manage, Quiet Therapeutics aims to expand the repertoire of drug targets, ultimately improving patient outcomes and quality of life.

cCAM Biotherapeutics

Series A in 2012
cCAM Biotherapeutics Ltd. is a clinical-stage biotechnology company based in Misgav, Israel, focused on the discovery and development of innovative immunotherapies for cancer treatment. The company is developing CM-10, an immunomodulatory antibody designed to enhance the immune system's ability to target and attack tumors by binding to CEACAM1, a protein that cancer cells exploit to evade immune responses. cCAM's lead therapeutic candidate, CM-24, is a humanized anti-CEACAM1 monoclonal antibody aimed at treating advanced and recurrent cancers, including melanoma, non-small-cell lung cancer, bladder, gastric, colorectal, and ovarian cancers. Established in 2010, cCAM Biotherapeutics aims to provide effective treatment options for patients facing various malignancies.

Rhino Federated Computing

The value of connecting disparate datasets is immense, yet much of this potential remains untapped. Imagine the transformative possibilities: pharmaceutical companies sharing data to design better drugs and evaluate their real-world value, hospitals and HMOs diagnosing rare diseases faster, or financial institutions collaborating to combat financial crime. Rhino Federated Computing makes this vision a reality. Our federated computing platform, powered by advanced edge-computing and federated learning technologies, enables organizations to train and deploy AI models on massive, distributed datasets—without sharing sensitive information or compromising data privacy and sovereignty. This breakthrough approach was pioneered by our co-founder and CEO, Dr. Ittai Dayan, a recognized leader in the field whose work includes a landmark Nature Medicine publication in 2021.
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