Atlas Venture

HotSpot Therapeutics is a biotechnology startup based in Boston, Massachusetts, established in 2017. The company specializes in the development of allosteric therapies that target regulatory sites on proteins. Its innovative therapeutic platform is designed to identify hotspots and locate pathway treatments for cancer, metabolic disorders, and rare diseases. By leveraging a comprehensive database of hotspot structures and utilizing data science, HotSpot Therapeutics employs a multidisciplinary approach to drug discovery. This approach aims to enhance the effectiveness of treatments and improve patient outcomes across a range of conditions.

Ikena Oncology, Inc. is a biotechnology company focused on discovering and developing biomarker-driven therapies for cancer treatment. It specializes in precision oncology by targeting pathways essential for cancer growth and therapeutic resistance, particularly within the Hippo and RAS signaling networks. The company's portfolio includes several preclinical and discovery-stage programs, such as IK-007, an EP4 receptor antagonist; IK-175, an AHR antagonist; and IK-412, a kynurenine-degrading enzyme. Additionally, Ikena is developing IK-930, an oral small-molecule inhibitor of the TEAD transcription factor involved in the Hippo pathway. Ikena Oncology, originally founded as Kyn Therapeutics in 2016, rebranded in December 2019 and is headquartered in Boston, Massachusetts. The company aims to address significant medical needs in oncology through innovative drug development.

HotSpot Therapeutics is a biotechnology startup based in Boston, Massachusetts, established in 2017. The company specializes in the development of allosteric therapies that target regulatory sites on proteins. Its innovative therapeutic platform is designed to identify hotspots and locate pathway treatments for cancer, metabolic disorders, and rare diseases. By leveraging a comprehensive database of hotspot structures and utilizing data science, HotSpot Therapeutics employs a multidisciplinary approach to drug discovery. This approach aims to enhance the effectiveness of treatments and improve patient outcomes across a range of conditions.

HotSpot Therapeutics is a biotechnology startup based in Boston, Massachusetts, established in 2017. The company specializes in the development of allosteric therapies that target regulatory sites on proteins. Its innovative therapeutic platform is designed to identify hotspots and locate pathway treatments for cancer, metabolic disorders, and rare diseases. By leveraging a comprehensive database of hotspot structures and utilizing data science, HotSpot Therapeutics employs a multidisciplinary approach to drug discovery. This approach aims to enhance the effectiveness of treatments and improve patient outcomes across a range of conditions.

Ikena Oncology, Inc. is a biotechnology company focused on discovering and developing biomarker-driven therapies for cancer treatment. It specializes in precision oncology by targeting pathways essential for cancer growth and therapeutic resistance, particularly within the Hippo and RAS signaling networks. The company's portfolio includes several preclinical and discovery-stage programs, such as IK-007, an EP4 receptor antagonist; IK-175, an AHR antagonist; and IK-412, a kynurenine-degrading enzyme. Additionally, Ikena is developing IK-930, an oral small-molecule inhibitor of the TEAD transcription factor involved in the Hippo pathway. Ikena Oncology, originally founded as Kyn Therapeutics in 2016, rebranded in December 2019 and is headquartered in Boston, Massachusetts. The company aims to address significant medical needs in oncology through innovative drug development.

Allclasses, Inc. is an online search engine founded in 2013 and based in Boston, Massachusetts, that connects users to a diverse range of classes and educational experiences, both online and in-person. As a subsidiary of Noodle Education, Inc., Allclasses aims to facilitate lifelong learning by providing an intuitive platform for individuals to discover and evaluate classes across various fields, including academics, professional development, fitness, and the arts. The platform is designed to help users navigate their options based on accessibility, cost, and quality, promoting a user-friendly experience. Allclasses stands out as a comprehensive resource for anyone seeking to enhance their skills and knowledge, emphasizing a commitment to making education more accessible and tailored to individual needs.

dataxu, inc. is a marketing analytics software company that provides solutions for brand marketers and agencies globally. Founded in 2007 and headquartered in Boston, Massachusetts, the company offers a range of products including TouchPoint, a demand side platform for multi-channel marketing; OneView, which helps marketers build a comprehensive understanding of consumer behavior; and the Marketing Intelligence Center, a dashboard that consolidates data and performance metrics. Other offerings include ClearSight, an analytics platform for customer insights, and TotalTV, which facilitates audience-based targeting across various TV formats. dataxu also produces insights through white papers and reports, and provides training and managed services for its platform users. The company serves diverse industries such as automotive, financial services, and consumer packaged goods. As a subsidiary of Roku, Inc., dataxu continues to focus on enhancing marketing effectiveness through data-driven strategies.

dataxu, inc. is a marketing analytics software company that provides solutions for brand marketers and agencies globally. Founded in 2007 and headquartered in Boston, Massachusetts, the company offers a range of products including TouchPoint, a demand side platform for multi-channel marketing; OneView, which helps marketers build a comprehensive understanding of consumer behavior; and the Marketing Intelligence Center, a dashboard that consolidates data and performance metrics. Other offerings include ClearSight, an analytics platform for customer insights, and TotalTV, which facilitates audience-based targeting across various TV formats. dataxu also produces insights through white papers and reports, and provides training and managed services for its platform users. The company serves diverse industries such as automotive, financial services, and consumer packaged goods. As a subsidiary of Roku, Inc., dataxu continues to focus on enhancing marketing effectiveness through data-driven strategies.

dataxu, inc. is a marketing analytics software company that provides solutions for brand marketers and agencies globally. Founded in 2007 and headquartered in Boston, Massachusetts, the company offers a range of products including TouchPoint, a demand side platform for multi-channel marketing; OneView, which helps marketers build a comprehensive understanding of consumer behavior; and the Marketing Intelligence Center, a dashboard that consolidates data and performance metrics. Other offerings include ClearSight, an analytics platform for customer insights, and TotalTV, which facilitates audience-based targeting across various TV formats. dataxu also produces insights through white papers and reports, and provides training and managed services for its platform users. The company serves diverse industries such as automotive, financial services, and consumer packaged goods. As a subsidiary of Roku, Inc., dataxu continues to focus on enhancing marketing effectiveness through data-driven strategies.

dataxu, inc. is a marketing analytics software company that provides solutions for brand marketers and agencies globally. Founded in 2007 and headquartered in Boston, Massachusetts, the company offers a range of products including TouchPoint, a demand side platform for multi-channel marketing; OneView, which helps marketers build a comprehensive understanding of consumer behavior; and the Marketing Intelligence Center, a dashboard that consolidates data and performance metrics. Other offerings include ClearSight, an analytics platform for customer insights, and TotalTV, which facilitates audience-based targeting across various TV formats. dataxu also produces insights through white papers and reports, and provides training and managed services for its platform users. The company serves diverse industries such as automotive, financial services, and consumer packaged goods. As a subsidiary of Roku, Inc., dataxu continues to focus on enhancing marketing effectiveness through data-driven strategies.

Founded in 1999, GetConnected is a privately held company where smart and motivated professionals are working together to provide the technology and the services to help alternate channels successfully sell digital services such as broadband, wireless, digital and high definition cable video, and satellite TV. Located in downtown Boston on the edge of the famous North End, GetConnected has seen its business transform from a wireless commerce portal to becoming the market-leading transaction processing platform for selling digital services. Their ASP solution ties together the shopping for digital services, which is occurring at retailers’ stores, on e-tailers’ sites, and through call centers, to the service providers to whom orders are conveyed, processed, and then status updated.

Founded in 1999, GetConnected is a privately held company where smart and motivated professionals are working together to provide the technology and the services to help alternate channels successfully sell digital services such as broadband, wireless, digital and high definition cable video, and satellite TV. Located in downtown Boston on the edge of the famous North End, GetConnected has seen its business transform from a wireless commerce portal to becoming the market-leading transaction processing platform for selling digital services. Their ASP solution ties together the shopping for digital services, which is occurring at retailers’ stores, on e-tailers’ sites, and through call centers, to the service providers to whom orders are conveyed, processed, and then status updated.

Founded in 1999, GetConnected is a privately held company where smart and motivated professionals are working together to provide the technology and the services to help alternate channels successfully sell digital services such as broadband, wireless, digital and high definition cable video, and satellite TV. Located in downtown Boston on the edge of the famous North End, GetConnected has seen its business transform from a wireless commerce portal to becoming the market-leading transaction processing platform for selling digital services. Their ASP solution ties together the shopping for digital services, which is occurring at retailers’ stores, on e-tailers’ sites, and through call centers, to the service providers to whom orders are conveyed, processed, and then status updated.