Enlaza Therapeutics
Series A in 2024
Enlaza Therapeutics is a biotechnology research company founded in 2020 and headquartered in La Jolla, California. The company focuses on developing novel protein therapeutics aimed at providing more effective and safer treatment options for patients. Utilizing advanced synthetic biology technology, Enlaza Therapeutics specializes in site-specific covalent coupling driven by drug binding. This innovative approach allows the development of first-in-class covalent biologics that have the potential to deliver enhanced efficacy and improved safety profiles compared to traditional therapies.
Vocera Communications
Post in 2023
Vocera Communications, Inc. specializes in providing secure and integrated communication and workflow solutions tailored for mobile workers across various sectors, including healthcare, hospitality, retail, energy, and education. The company’s offerings enhance communication and operational efficiency by integrating with existing clinical systems, such as electronic health records and nurse call systems. Vocera's product suite includes the Vocera Communication and Workflow System, which connects various communication devices, including hands-free and voice-controlled options, and the Vocera Care Experience software, designed to improve patient care quality and streamline manual tasks. Additionally, Vocera operates the Experience Innovation Network, collaborating with healthcare organizations to develop innovative solutions that improve patient and care team experiences. The company, founded in 2000 and headquartered in San Jose, California, serves approximately 1,700 healthcare facilities globally, including hospitals and clinics, and distributes its products through direct sales, resellers, and distributors.
Jnana Therapeutics
Series C in 2022
Jnana Therapeutics Inc. is a biotechnology company based in Boston, Massachusetts, founded in 2016. It specializes in drug discovery, particularly focusing on solute carrier (SLC) transporters, which are vital for understanding various disease pathways. The company’s efforts are directed towards immunometabolism, lysosomal function, and mucosal defense, with applications in immuno-oncology, inflammatory disorders, and neurological diseases. Utilizing its proprietary RAPID platform, Jnana accelerates the identification of therapeutic targets and the development of small molecule therapies. By leveraging advanced chemoproteomics techniques, the company aims to enhance the efficiency of drug discovery and address significant unmet medical needs in patient care.
Enlaza Therapeutics
Venture Round in 2022
Enlaza Therapeutics is a biotechnology research company founded in 2020 and headquartered in La Jolla, California. The company focuses on developing novel protein therapeutics aimed at providing more effective and safer treatment options for patients. Utilizing advanced synthetic biology technology, Enlaza Therapeutics specializes in site-specific covalent coupling driven by drug binding. This innovative approach allows the development of first-in-class covalent biologics that have the potential to deliver enhanced efficacy and improved safety profiles compared to traditional therapies.
Jnana Therapeutics
Series B in 2021
Jnana Therapeutics Inc. is a biotechnology company based in Boston, Massachusetts, founded in 2016. It specializes in drug discovery, particularly focusing on solute carrier (SLC) transporters, which are vital for understanding various disease pathways. The company’s efforts are directed towards immunometabolism, lysosomal function, and mucosal defense, with applications in immuno-oncology, inflammatory disorders, and neurological diseases. Utilizing its proprietary RAPID platform, Jnana accelerates the identification of therapeutic targets and the development of small molecule therapies. By leveraging advanced chemoproteomics techniques, the company aims to enhance the efficiency of drug discovery and address significant unmet medical needs in patient care.
Primer Technologies, Inc., established in 2014 and headquartered in San Francisco, specializes in developing software that leverages machine learning and natural language processing to analyze vast amounts of textual data across multiple languages. Its platform automates the parsing and collation of documents, uncovering insights and generating reports comparable to those produced by human analysts. This enables governments and corporations to better understand and monitor global information, facilitating informed decision-making.
Fortis Therapeutics
Series A in 2021
Fortis Therapeutics is a biotechnology company specializing in immuno-oncology. The firm is focused on developing innovative antibody-drug conjugate therapies targeting CD46, aimed at treating late-stage multiple myeloma and prostate cancer, among other indications. Utilizing its platform, Fortis Therapeutics prepares antibody-drug conjugates that are designed to effectively address both adenocarcinoma and neuroendocrine cancers, providing oncologists with new therapeutic options for challenging late-stage malignancies.
Janux Therapeutics
Series A in 2021
Janux Therapeutics is a clinical-stage biopharmaceutical company focused on developing innovative immunotherapies aimed at treating cancer. Utilizing its proprietary tumor-activated T Cell Engager platform technology, Janux aims to generate targeted immune responses that effectively combat tumors while minimizing effects on healthy tissue. The company's approach seeks to enhance all three stages of the anti-tumor immune response, making it a promising player in the field of cancer treatment.
Pando has developed a financial platform aimed at individuals in high-volatility careers, such as professional athletes, entrepreneurs, and MBA graduates. The platform enables users to connect with others who have similar expected earnings, allowing them to pool a fraction of their future income. This innovative approach not only helps mitigate financial risks associated with unpredictable income but also allows participants to benefit from potential upside. By providing these tools, Pando empowers its clients to better manage their financial futures and protect their earnings.
Figg
Funding Round in 2020
Figg is a card-linked marketing company that provides a digital advertising platform designed to enhance value through everyday transactions. Its unique platform enables brands to market effectively within a private marketplace that includes banks and publishers. By partnering with these financial institutions and publishers, Figg offers advertiser-funded promotions to consumers, fostering loyalty and engagement. The platform allows consumers to enroll any credit or debit card, facilitating incremental cash-back rewards through targeted offers. With access to powerful transaction data, Figg enables advertisers to reach specific consumer segments with precise targeting and accurate tracking of marketing expenditures, benefiting both businesses and consumers alike.
Orion Labs
Series B in 2020
Orion Labs, Inc. is a voice communication and workflow platform designed for mobile and deskless teams, facilitating instant and secure voice, location, and data messaging across various connected devices and applications. Founded in 2013 and headquartered in San Francisco, the company offers solutions such as a push-to-talk app, dispatch console, command center, advanced location services, and AI workflows, which enhance collaboration for industries including hospitality, healthcare, transportation, and construction. Orion's platform is designed to work seamlessly with traditional VoIP and Land Mobile Radio systems, and it provides APIs and SDKs for developers to extend its capabilities. The company, originally known as OnBeep, Inc., rebranded to Orion Labs in 2015. Orion has formed strategic alliances with organizations such as ResponderXLabs and the FirstNet Association and has gained recognition in the industry, including being named an IDC Innovator and receiving multiple awards for its technology solutions.
AristaMD is a digital health company based in La Jolla, California, founded in 2013. It specializes in enhancing the specialty referral process through its eConsult platform. This platform equips primary care providers with clinical workup checklists and enables electronic consultations with specialists. AristaMD's solution allows payers and providers to initiate specialist eConsults using their own specialists or those from AristaMD’s board-certified panel. The platform facilitates the transmission of patient clinical notes, history, lab results, and images, fostering collaboration on care plans within hours. This approach aims to improve patient outcomes by providing timely access to specialty care and reducing referral wait times.
Simulmedia
Series E in 2019
Simulmedia Inc. is a technology company based in New York with an additional location in San Francisco, specializing in a digital advertisement targeting platform for linear television. Founded in 2008, Simulmedia has established itself as a leader in cross-channel TV advertising through its TV+ platform, which enables advertisers to effectively reach audiences across both linear and connected TV. The company utilizes a data-driven approach, leveraging predictive analytics through its VAMOS platform to optimize TV ad placement and measurement. By combining the agility of digital advertising with the broad reach of television, Simulmedia provides marketers, agencies, and media owners with tools to conduct efficient marketing campaigns, assess outcomes, and receive optimization recommendations in near-real time.
Seva is a cloud-based information discovery and collaboration platform founded in late 2017 and launched in mid-2018, based in New York City. The company focuses on enhancing workplace efficiency by providing teams with a centralized source of information that integrates various applications, including email, messaging, and document management. By serving as a "digital teammate," Seva streamlines the process of finding information, allowing knowledge workers to access crucial data quickly and effectively, thereby minimizing time spent searching through documents. This approach empowers users to work smarter and faster within the modern work environment.
Joy Life, Inc. is a San Francisco-based company that offers a comprehensive wedding planning portal and application designed to assist users from engagement through to their honeymoon. Founded in 2014, Joy's platform provides tools for organizing wedding details, including customizable checklists, wedding websites, and mobile applications. Users can manage guest lists, send digital or printed invitations, track RSVPs, and link gift registries. The application also fosters interaction among wedding guests by allowing photo sharing and comments on a private timeline. Additionally, Joy offers features for sending custom notifications and messages, enabling a seamless planning experience for couples and their wedding parties.
Memrise is a London-based online learning platform, established in 2010, offering a wide array of courses in languages, arts, sciences, and more. It provides over 150 language courses across 25 languages, with no ads and free access for all users. Memrise's platform enables teachers to create and manage courses, serving users in the United States, the United Kingdom, the Netherlands, and internationally. Since late 2016, the company has been profitable and has amassed over 40 million registered users.
BotChain
Venture Round in 2018
BotChain enables universal registration, identity validation, audit, and coordination of A.I. agents and autonomous software. The BotChain was created by the team at Talla. After more than two years of building intelligent, AI-driven bots for the enterprise, Talla began pursuing their idea for BotChain. The leadership team represents decades of experience in software development, Artificial Intelligence, startups, and innovation.
Synthorx, Inc. is a biopharmaceutical company specializing in the development of innovative protein therapeutics using advanced synthetic biology techniques. Founded in 2014 and headquartered in La Jolla, California, Synthorx focuses on its proprietary Synthorin programs aimed at treating cancer and autoimmune disorders. Its lead product candidate, THOR-707, is a modified form of recombinant human IL-2, currently being evaluated for various solid tumors both as a standalone treatment and in combination with immune checkpoint inhibitors. The company also develops Synthorins targeting IL-2 for autoimmune conditions, IL-10 for immuno-oncology applications, and IL-15 for regulating immune responses. Synthorx leverages a unique platform that enables the incorporation of synthetic DNA base pairs to enhance the specificity and efficacy of its protein therapeutics, thus offering improved treatment options for patients. Previously known as Alinos, Inc., the company acquired exclusive rights to its synthetic biology technology based on groundbreaking research from The Scripps Research Institute. As of January 2020, Synthorx operates as a subsidiary of Sanofi.
Averon US, Inc. specializes in mobile identity verification technology, focusing on its Direct Autonomous Authentication (DAA) standard. This innovative approach allows smartphone users to securely interact with a variety of services, such as banking, e-commerce, and smart locks, without the need for dedicated applications or software installations. By utilizing real-time mobile network signaling and SIM/eSIM chips, Averon provides seamless authentication that requires no user involvement, ensuring both privacy and security. Founded in 2015 and based in San Francisco, the company is committed to enhancing online identity verification while eliminating reliance on personally identifiable information. Supported by 35 patents, Averon's technology is adopted by leading firms in various sectors, including transportation and digital currency, creating a streamlined and secure user experience.
Pando has developed a financial platform aimed at individuals in high-volatility careers, such as professional athletes, entrepreneurs, and MBA graduates. The platform enables users to connect with others who have similar expected earnings, allowing them to pool a fraction of their future income. This innovative approach not only helps mitigate financial risks associated with unpredictable income but also allows participants to benefit from potential upside. By providing these tools, Pando empowers its clients to better manage their financial futures and protect their earnings.
Jnana Therapeutics
Series A in 2017
Jnana Therapeutics Inc. is a biotechnology company based in Boston, Massachusetts, founded in 2016. It specializes in drug discovery, particularly focusing on solute carrier (SLC) transporters, which are vital for understanding various disease pathways. The company’s efforts are directed towards immunometabolism, lysosomal function, and mucosal defense, with applications in immuno-oncology, inflammatory disorders, and neurological diseases. Utilizing its proprietary RAPID platform, Jnana accelerates the identification of therapeutic targets and the development of small molecule therapies. By leveraging advanced chemoproteomics techniques, the company aims to enhance the efficiency of drug discovery and address significant unmet medical needs in patient care.
ScoreStream
Series A in 2017
ScoreStream, Inc. is a communication platform that specializes in mobile applications designed for sharing information about sporting events, particularly high school sports. Founded in 2012 and headquartered in San Diego, California, the company’s platform includes both iOS and Android applications, as well as a website. ScoreStream engages fans by allowing them to crowd-source scores, photos, videos, and conversations from numerous games each week. This user-generated content not only enhances the experience for fans but also provides accurate reporting and coverage of local sports, catering to consumers and media companies alike. The company's former name was Crowdscores, Inc., and it has collaborated with notable clients such as ESPN and Walt Disney Internet Group.
Averon US, Inc. specializes in mobile identity verification technology, focusing on its Direct Autonomous Authentication (DAA) standard. This innovative approach allows smartphone users to securely interact with a variety of services, such as banking, e-commerce, and smart locks, without the need for dedicated applications or software installations. By utilizing real-time mobile network signaling and SIM/eSIM chips, Averon provides seamless authentication that requires no user involvement, ensuring both privacy and security. Founded in 2015 and based in San Francisco, the company is committed to enhancing online identity verification while eliminating reliance on personally identifiable information. Supported by 35 patents, Averon's technology is adopted by leading firms in various sectors, including transportation and digital currency, creating a streamlined and secure user experience.
Talla, Inc., founded in 2015 and based in Brookline, Massachusetts, is an AI and automation platform that enhances customer support and internal service management. The company develops software that automates support workflows, enabling users to find accurate answers to their questions through self-service. Talla's platform is designed for various internal teams, including HR and IT, and prioritizes inquiries while automating responses to frequently asked questions. By integrating with essential tools used by support teams, Talla not only improves customer satisfaction but also increases the productivity of support representatives. The platform's machine learning capabilities allow it to learn and adapt over time, ensuring continuous improvement in service delivery.
Nanonets
Seed Round in 2017
Nanonets is an AI-driven company that specializes in automating document processing and data extraction workflows through advanced Optical Character Recognition and deep learning technologies. By focusing on unstructured documents such as invoices, receipts, contracts, and forms, Nanonets transforms these into structured data, streamlining document-heavy business processes like accounts payable and order processing. The company's machine learning-based API allows clients to easily integrate its solutions into existing systems with minimal code requirements, enhancing productivity without necessitating complex databases. Nanonets' offerings significantly reduce manual effort—by up to 90%—while providing high accuracy, speed, and substantial cost savings of up to 50%.
Smyte Inc. is a Software-as-a-Service company based in San Francisco, California, specializing in trust and safety solutions for websites and mobile applications. Founded in 2014, Smyte employs a combination of manual heuristics, machine learning, and proprietary reputation data to assist organizations in proactively combating spam, fraud, bots, phishing, harassment, and account takeovers. The company caters to a diverse clientele that includes enterprises, marketplaces, and social networks, processing nearly five billion online actions each month. Smyte's automated labeling system identifies potentially malicious activities by analyzing various signals, allowing risk teams to effectively manage threats. As of June 30, 2018, Smyte operates as a subsidiary of Twitter, Inc.
Piper Networks
Venture Round in 2017
Piper Networks specializes in advanced tracking solutions for transportation systems by delivering real-time location awareness through its proprietary technology. The company employs Ultra-Wideband (UWB) and Bluetooth Low Energy (BLE) to achieve high performance, providing location accuracy within 10 centimeters while minimizing signal latency and interference. This capability is particularly beneficial in challenging environments, such as underground transit systems. In addition to tracking, Piper Networks offers a proximity-based messaging and data capture platform that enhances customer engagement through contextual information delivered to smartphones. The platform supports a variety of beacon devices and includes a content dashboard for creating diverse messaging options, helping clients improve analytics and manage inventory effectively.
Fortis Therapeutics
Series A in 2016
Fortis Therapeutics is a biotechnology company specializing in immuno-oncology. The firm is focused on developing innovative antibody-drug conjugate therapies targeting CD46, aimed at treating late-stage multiple myeloma and prostate cancer, among other indications. Utilizing its platform, Fortis Therapeutics prepares antibody-drug conjugates that are designed to effectively address both adenocarcinoma and neuroendocrine cancers, providing oncologists with new therapeutic options for challenging late-stage malignancies.
Avelas Biosciences
Series C in 2016
Avelas Biosciences is focused on advancing cancer surgery through innovative intraoperative imaging technology. The company has developed a proprietary platform that utilizes activatable cell-penetrating peptides to provide real-time diagnosis of metastatic nodes during surgical procedures. This technology enables oncologic surgeons to create a luminous map of the surgical area, improving their ability to identify and remove cancerous tissue effectively. By enhancing surgical precision, Avelas Biosciences aims to reduce the need for repeat surgeries and ultimately improve patient outcomes, establishing a new standard of care in oncological surgery.
AristaMD is a digital health company based in La Jolla, California, founded in 2013. It specializes in enhancing the specialty referral process through its eConsult platform. This platform equips primary care providers with clinical workup checklists and enables electronic consultations with specialists. AristaMD's solution allows payers and providers to initiate specialist eConsults using their own specialists or those from AristaMD’s board-certified panel. The platform facilitates the transmission of patient clinical notes, history, lab results, and images, fostering collaboration on care plans within hours. This approach aims to improve patient outcomes by providing timely access to specialty care and reducing referral wait times.
Synthorx, Inc. is a biopharmaceutical company specializing in the development of innovative protein therapeutics using advanced synthetic biology techniques. Founded in 2014 and headquartered in La Jolla, California, Synthorx focuses on its proprietary Synthorin programs aimed at treating cancer and autoimmune disorders. Its lead product candidate, THOR-707, is a modified form of recombinant human IL-2, currently being evaluated for various solid tumors both as a standalone treatment and in combination with immune checkpoint inhibitors. The company also develops Synthorins targeting IL-2 for autoimmune conditions, IL-10 for immuno-oncology applications, and IL-15 for regulating immune responses. Synthorx leverages a unique platform that enables the incorporation of synthetic DNA base pairs to enhance the specificity and efficacy of its protein therapeutics, thus offering improved treatment options for patients. Previously known as Alinos, Inc., the company acquired exclusive rights to its synthetic biology technology based on groundbreaking research from The Scripps Research Institute. As of January 2020, Synthorx operates as a subsidiary of Sanofi.
Node, recently acquired by SugarCRM, fuels Sugar's time-aware CX platform to help businesses by automatically forecasting expected outcomes and highlighting previously unforeseen challenges and opportunities. Extending Sugar’s time-aware CX platform, Node’s AI technology adds the most coveted element of time—the future. The combined solution offers wide-ranging capabilities for sales, marketing, and service teams. Node enables users of business applications to see into the future. Powered by Artificial Intuition™ technology, Node is the first turnkey AI-as-a-service platform focused on powering predictable business outcomes, which enterprises can use to quickly and seamlessly build advanced AI into both customer-facing and internal applications without investing years and millions of dollars on risky AI experiments. Applications powered by Node can deliver predictions that enable users to make smarter connections and decisions about how to engage with customers, employees, investors, and partners. Node was founded by Google's youngest employee, Falon Fatemi, and it's renowned technology team includes the Godfather of Search, Louis Monier who created Alta Vista, and Michael Radovancevich former CTO of Taleo and OpenX. Node is backed by Mark Cuban, NEA, Avalon Ventures, and JetBlue Technology Ventures.
Orion Labs
Series A in 2016
Orion Labs, Inc. is a voice communication and workflow platform designed for mobile and deskless teams, facilitating instant and secure voice, location, and data messaging across various connected devices and applications. Founded in 2013 and headquartered in San Francisco, the company offers solutions such as a push-to-talk app, dispatch console, command center, advanced location services, and AI workflows, which enhance collaboration for industries including hospitality, healthcare, transportation, and construction. Orion's platform is designed to work seamlessly with traditional VoIP and Land Mobile Radio systems, and it provides APIs and SDKs for developers to extend its capabilities. The company, originally known as OnBeep, Inc., rebranded to Orion Labs in 2015. Orion has formed strategic alliances with organizations such as ResponderXLabs and the FirstNet Association and has gained recognition in the industry, including being named an IDC Innovator and receiving multiple awards for its technology solutions.
AlphaSheets
Seed Round in 2015
AlphaSheets is a Boston-based company that offers a cloud-based, programmable spreadsheet platform designed for financial analytics, business intelligence, risk management, and bioinformatics. The company's main product, AlphaSheets, aims to address common issues found in traditional enterprise spreadsheets by providing an intuitive and visually appealing user experience. The platform enables users to import data and functions from various sources, facilitating comprehensive analysis and visualizations. By focusing on enhancing usability and functionality, AlphaSheets seeks to transform how organizations interact with and leverage spreadsheet tools in their operations.
Enlibrium
Series A in 2015
Enlibrium is developing novel drugs based on metformin to treat a range of different cancers by reducing cancer energy consumption and reestablishing energy balance. Given their high growth rate and energy requirements, cancers are particularly sensitive to agents that reduce their energy production. Enlibrium was founded based on technology exclusively licensed from UCLA and developed in laboratories headed by Michael Jung, Ph.D. and Richard Pietras, M.D., Ph.D. Enlibrium's investors are Avalon Ventures, TPG Biotech, Correlation Ventures and Osage University Partners.
Skycatch, Inc. is a technology company that specializes in aerial data capture and 3D rendering, primarily for the construction and mining industries. Founded in 2013 and based in San Francisco, the company develops the Evolution3 drone, designed for real-time data collection and analysis. Skycatch’s offerings include the Commander app, which allows users to operate the drone, and the Skycatch Dashboard, a software platform for data analysis and collaborative viewing. The company utilizes a blend of advanced hardware, software, and artificial intelligence to provide high-precision data rapidly and efficiently. In addition to its core products, Skycatch offers engineering support, training, and integration services, positioning itself as a leader in industrial data collection and analytics.
MOGL
Venture Round in 2015
MOGL is a restaurant rewards application dedicated to combating hunger in the United States. Members can earn 10% cash-back at thousands of participating restaurants by using a linked credit or debit card for their payments. Shortly after making a purchase, members receive an alert that allows them to donate a portion or the entirety of their cash-back to a local food bank. The app features a Hunger Tracker, enabling users to monitor the impact of their donations in their communities and engage in friendly competition with friends to see who can contribute the most meals. Founded in 2010, MOGL is headquartered in Solana Beach, California.
Empyr
Venture Round in 2015
Empyr, Inc. is a San Diego-based company that operates an online-to-offline advertisement platform designed to connect digital engagement with real-world purchases. Established in 2011, Empyr specializes in card-linked offers, enabling national brands and digital publishers to track online advertisements that lead to offline sales. By integrating directly with major credit card associations, Empyr allows consumers to earn cashback at offline merchants simply by using their debit or credit cards. This platform provides a seamless experience for users while offering publishers the ability to generate revenue from each purchase and allowing merchants to link offline sales to specific online marketing efforts. Empyr collaborates with a diverse range of partners, including notable names in technology, banking, and hospitality, thereby tapping into the significant potential of the $3 trillion offline commerce market driven by online activity. The company has raised $35 million through its parent organization, Mogl, and currently employs 60 individuals.
AeroFS is a company specializing in enterprise file synchronization and secure data sharing solutions. Their primary platform, Amium, facilitates intuitive and efficient collaboration among creative agencies, consultants, freelancers, and work teams, both within organizations and with external users. AeroFS ensures data privacy and control by storing files on client-designated devices and offering software that can operate entirely behind a firewall, including authentication processes. The company aims to redefine the traditional concept of cloud storage by providing enhanced controls, privacy, and scalability for administrators and end-users alike.
Ankasa Regenerative Therapeutics
Series A in 2015
Ankasa Regenerative Therapeutics is a biopharmaceutical company based in La Jolla, California, founded in 2014. The company focuses on enhancing tissue healing by reactivating stem cells. It develops proprietary formulations of a potent WNT stem cell activator, aiming to accelerate tissue repair in various degenerative conditions affecting bone, cartilage, skin, muscle, vasculature, and the central nervous system. Ankasa's approach has shown superior bone reformation compared to existing standards of care in preclinical models. The company's therapies are designed to improve tissue repair and regeneration, particularly enhancing the osteogenic properties of patient-derived stem cells used in reconstructive surgeries. This aims to reduce revision surgery rates and associated complications.
Indix is a provider of product information management services that aims to assist businesses and developers in making informed decisions and enhancing sales. The company has developed a Products Platform that integrates artificial intelligence with an extensive collection of product data, including price, availability, and seller information, along with unique identifiers and attributes. This platform enables organizations to improve the size and quality of their digital product catalogs, while also offering tools for big data analytics and visualizations. By leveraging these capabilities, Indix helps clients optimize their product portfolios and increase operational efficiency.
Vook, formerly known as Pronoun, is a publishing company offering digital and print book creation, distribution, cover design, and copy editing services. They leverage technology and data to assist authors in publishing swiftly, marketing effectively, and retaining creative and financial autonomy over their works.
Calporta Therapeutics
Series A in 2015
Calporta is developing selective small molecule agonists of TRPML1 (transient receptor potential cation channel, mucolipin subfamily, member 1) for the treatment of Niemann-Pick C Disease (NPC) and other lysosomal storage diseases. Mutations that cause NPC lead to impaired intracellular lipid trafficking and lead to lysosomal accumulation of cholesterol and biolipds. TRPML1 is an ion channel in the lysosome and a key regulator of lysosomal trafficking processes. Impaired TRPML1 function has been implicated in multiple pathological conditions, including NPC. Agonists of TRPML1 restore calcium efflux and normalize lysosomal trafficking and function. In addition to NPC and other lysosomal storage diseases, agonists of TRPML1 may have broad potential in other diseases such as muscular dystrophy and various taopathies such as Alzheimer's disease. Calporta's approach is based on research from the lab of Haoxing Xu, Ph.D., at the University of Michigan.
Cadherx Therapeutics
Series A in 2015
Cadherx Therapeutics develops therapeutic antibodies targeting soluble E-cadherin.
BookBub is a rapidly growing startup launched by serial entrepreneurs and run by a team gathered from the publishing and tech industries. Every day millions of readers use our service to discover great books, and thousands of leading publishers and authors work with us to drive sales and find new fans. Connecting readers with great deals on ebooks is just the beginning for BookBub. The rise of digital publishing is altering the way books are found, purchased, and read. We’re expanding our team to help address the challenges and opportunities of the publishing industry while continuing to help readers find books and authors they’ll love.
Tapad Inc., established in 2010, is a global marketing technology company headquartered in New York with offices worldwide. It specializes in providing identity-based marketing solutions, primarily its proprietary Tapad Graph. This technology integrates billions of data points to understand consumer behavior across various devices, enabling publishers and advertisers to engage consumers more effectively and personalize campaigns at scale. Tapad's offerings include The Tapad Customer Data Platform for managing first-party data, Device Graph Access for targeting workflows, Applied Analytics suite for campaign performance tracking, and Dynamic Audiences for precise cross-device targeting. Serving agency trading desks, publishers, marketing technology companies, and Fortune 500 brands, Tapad operates as a subsidiary of Experian plc since November 2020.
Cardeas Pharma
Series B in 2015
Cardeas Pharma is focused on developing an innovative antibiotic formulation that combines two drugs to target highly resistant Gram-negative bacilli, such as Pseudomonas aeruginosa and Acinetobacter baumannii, as well as carbapenem-resistant Enterobacteriaceae. This formulation is designed to treat serious respiratory infections in critical care settings, particularly those caused by antibiotic-resistant organisms. Additionally, it demonstrates efficacy against Gram-positive pathogens, including methicillin-resistant Staphylococcus aureus (MRSA), and has activity on biofilms. The delivery system utilizes a single-patient use, vibrating-plate nebulizer compatible with all ventilators, which generates small, uniform aerosol droplets that effectively reach the small airways and alveoli. By integrating this novel antibiotic formulation with advanced drug-delivery technology, Cardeas Pharma aims to achieve substantial clinical improvements over current treatment standards.
ScoreStream
Seed Round in 2015
ScoreStream, Inc. is a communication platform that specializes in mobile applications designed for sharing information about sporting events, particularly high school sports. Founded in 2012 and headquartered in San Diego, California, the company’s platform includes both iOS and Android applications, as well as a website. ScoreStream engages fans by allowing them to crowd-source scores, photos, videos, and conversations from numerous games each week. This user-generated content not only enhances the experience for fans but also provides accurate reporting and coverage of local sports, catering to consumers and media companies alike. The company's former name was Crowdscores, Inc., and it has collaborated with notable clients such as ESPN and Walt Disney Internet Group.
Nanigans is a Boston-based company that specializes in advertising automation software, designed to support in-house performance marketing teams. As a Software-as-a-Service provider, Nanigans offers a platform that features programmatic media buying, predictive revenue optimization, and real-time business intelligence. This comprehensive approach allows clients to enhance their advertising strategies and optimize revenue generation across various digital channels. In addition to its headquarters in Boston, Nanigans has established offices in New York, San Francisco, Seattle, London, Sydney, and Singapore, reflecting its global reach and commitment to serving a diverse client base.
Primer
Venture Round in 2015
Primer Technologies, Inc., established in 2014 and headquartered in San Francisco, specializes in developing software that leverages machine learning and natural language processing to analyze vast amounts of textual data across multiple languages. Its platform automates the parsing and collation of documents, uncovering insights and generating reports comparable to those produced by human analysts. This enables governments and corporations to better understand and monitor global information, facilitating informed decision-making.
StackRox
Seed Round in 2015
StackRox, Inc. is a cybersecurity company that specializes in container security and Kubernetes environments. Founded in 2014 and based in Mountain View, California, StackRox offers a Kubernetes-native security platform designed to protect cloud-native applications throughout their entire life cycle, from build to deploy to runtime. The platform provides deep visibility into container activities, enabling users to discover and categorize assets, generate summary reports, and log activities for auditing. It also protects cloud workloads by detecting various cyber threats, orchestrating threat responses through policy-driven workflows, and facilitating rapid threat hunting for effective root cause analysis. By integrating with existing DevOps and security tools, StackRox helps enterprises enforce security and compliance policies at scale, serving a diverse clientele that includes cloud-native companies, Global 2000 enterprises, and government agencies.
Primer Technologies, Inc., established in 2014 and headquartered in San Francisco, specializes in developing software that leverages machine learning and natural language processing to analyze vast amounts of textual data across multiple languages. Its platform automates the parsing and collation of documents, uncovering insights and generating reports comparable to those produced by human analysts. This enables governments and corporations to better understand and monitor global information, facilitating informed decision-making.
Conjur
Venture Round in 2014
Conjur is a developer of security software designed to support enterprises in automating their infrastructure while ensuring robust identity and access management. The company offers a platform that enables organizations to identify, authorize, and audit all service and user identities across various environments, including public and hybrid clouds, virtual machines, and containers. By focusing on the automation of machine identity provisioning, privileged access authorization, and service account control, Conjur addresses the critical operational and compliance challenges faced by businesses in highly automated software delivery processes. The platform enhances security by providing real-time monitoring and detailed activity reports, which are essential for compliance and security audits. With a growing emphasis on safeguarding sensitive IT systems amidst rising security threats, Conjur delivers vital infrastructure solutions that allow enterprises to adopt modern IT practices confidently. Its clientele includes notable organizations such as Discovery Communications, AOL, and Cisco.
Redbooth is a cloud-based task and project management platform that facilitates team collaboration by offering a centralized space for shared tasks, discussions, and file sharing. Founded in 2008 and headquartered in Palo Alto, California, the platform is designed to enhance productivity through features such as project management templates, real-time communication, and integration with various tools like Slack, Outlook, and Dropbox. Redbooth serves a diverse range of sectors, including marketing, finance, education, and legal services, and is utilized by over 400,000 organizations worldwide, including notable companies and institutions such as AT&T, BBC, and Harvard University. The platform is accessible on mobile, desktop, and smart devices, making it adaptable for remote and in-office teams.
MOGL
Venture Round in 2014
MOGL is a restaurant rewards application dedicated to combating hunger in the United States. Members can earn 10% cash-back at thousands of participating restaurants by using a linked credit or debit card for their payments. Shortly after making a purchase, members receive an alert that allows them to donate a portion or the entirety of their cash-back to a local food bank. The app features a Hunger Tracker, enabling users to monitor the impact of their donations in their communities and engage in friendly competition with friends to see who can contribute the most meals. Founded in 2010, MOGL is headquartered in Solana Beach, California.
Empyr
Venture Round in 2014
Empyr, Inc. is a San Diego-based company that operates an online-to-offline advertisement platform designed to connect digital engagement with real-world purchases. Established in 2011, Empyr specializes in card-linked offers, enabling national brands and digital publishers to track online advertisements that lead to offline sales. By integrating directly with major credit card associations, Empyr allows consumers to earn cashback at offline merchants simply by using their debit or credit cards. This platform provides a seamless experience for users while offering publishers the ability to generate revenue from each purchase and allowing merchants to link offline sales to specific online marketing efforts. Empyr collaborates with a diverse range of partners, including notable names in technology, banking, and hospitality, thereby tapping into the significant potential of the $3 trillion offline commerce market driven by online activity. The company has raised $35 million through its parent organization, Mogl, and currently employs 60 individuals.
StackIQ, Inc. is a technology company that specializes in server automation platforms tailored for diverse IT infrastructure requirements. Founded in 2006 and based in Solana Beach, California, StackIQ offers a software suite that automates the deployment, provisioning, and management of both small and large bare metal environments. The company’s flagship product, Stacki, is a Linux server provisioning tool that efficiently transitions systems from bare hardware to cluster-ready configurations, handling tasks such as OS installation, RAID controller setup, and network configuration. In addition to Stacki, StackIQ has developed Stacki Ace, an open-source version for the Raspberry Pi, and Stacki Pro, which supports multi-distribution cluster installations. Originally known as Clustercorp, the company changed its name to StackIQ in 2011 and is now a subsidiary of Teradata Corporation.
Kinvey, Inc. is a Boston-based company that provides a mobile backend as a service (mBaaS) platform designed to simplify the development of cloud backends for mobile, tablet, and web applications. Established in 2008, Kinvey enables developers and enterprises to focus on building their applications without the complexities of managing backend infrastructure. The platform automates the generation of APIs for accessing data, allowing developers to connect seamlessly to various cloud services and enterprise systems. Kinvey's solutions cater to diverse sectors, including healthcare, financial services, energy, and retail, by offering capabilities such as data storage, identity management, push notifications, and analytics. As of 2017, Kinvey operates as a subsidiary of Progress Software Corporation.
Silarus Therapeutics
Series A in 2014
Silarus Therapeutics is developing therapeutics targeting erythroferrone for the treatment of iron deficiency and iron overload disorders. Erythroferrone is a recently-discovered hormone that regulates the iron supply for red blood cell production. Iron deficiency, also known as anemia, is a condition in which blood does not contain the normal amount of red blood cells or lacks the proper amount of hemoglobin. This, in turn, lowers the amount of oxygen-rich blood in circulation, causing shortness of breath, dizziness or headaches.
Thyritope Biosciences
Series A in 2014
Thyritope Biosciences is developing therapeutics that target thyroid stimulating auto-antibodies, which are the causative drivers of Graves' hyperthyroidism and Graves' orbitopathy. Graves' disease is an autoimmune disorder caused by antibodies that over-stimulate the thyroid, causing excessive thyroid hormone production. The same antibodies stimulate the tissue around the eyes, resulting in an increase of orbital fat and extra-ocular muscle volume which causes the bulging of the eyes characteristic of Graves' orbitopathy.
Sidecar Technologies operates a B2B delivery transportation network that connects retailers with customers through a fleet of everyday drivers using their personal vehicles. Founded in San Francisco in 2011, Sidecar focuses on creating a convenient and affordable transportation solution powered by pre-vetted drivers who can choose when to offer rides. The company emphasizes safety through a comprehensive system that includes background checks, rating systems for both drivers and riders, GPS tracking, and real-time trip sharing. Currently, Sidecar operates in ten major U.S. cities and has facilitated over half a million rides, demonstrating its commitment to enhancing the delivery and driving experience.
Avelas Biosciences
Series B in 2014
Avelas Biosciences is focused on advancing cancer surgery through innovative intraoperative imaging technology. The company has developed a proprietary platform that utilizes activatable cell-penetrating peptides to provide real-time diagnosis of metastatic nodes during surgical procedures. This technology enables oncologic surgeons to create a luminous map of the surgical area, improving their ability to identify and remove cancerous tissue effectively. By enhancing surgical precision, Avelas Biosciences aims to reduce the need for repeat surgeries and ultimately improve patient outcomes, establishing a new standard of care in oncological surgery.
ScoreStream
Convertible Note in 2014
ScoreStream, Inc. is a communication platform that specializes in mobile applications designed for sharing information about sporting events, particularly high school sports. Founded in 2012 and headquartered in San Diego, California, the company’s platform includes both iOS and Android applications, as well as a website. ScoreStream engages fans by allowing them to crowd-source scores, photos, videos, and conversations from numerous games each week. This user-generated content not only enhances the experience for fans but also provides accurate reporting and coverage of local sports, catering to consumers and media companies alike. The company's former name was Crowdscores, Inc., and it has collaborated with notable clients such as ESPN and Walt Disney Internet Group.
Tapad Inc., established in 2010, is a global marketing technology company headquartered in New York with offices worldwide. It specializes in providing identity-based marketing solutions, primarily its proprietary Tapad Graph. This technology integrates billions of data points to understand consumer behavior across various devices, enabling publishers and advertisers to engage consumers more effectively and personalize campaigns at scale. Tapad's offerings include The Tapad Customer Data Platform for managing first-party data, Device Graph Access for targeting workflows, Applied Analytics suite for campaign performance tracking, and Dynamic Audiences for precise cross-device targeting. Serving agency trading desks, publishers, marketing technology companies, and Fortune 500 brands, Tapad operates as a subsidiary of Experian plc since November 2020.
Skycatch
Venture Round in 2014
Skycatch, Inc. is a technology company that specializes in aerial data capture and 3D rendering, primarily for the construction and mining industries. Founded in 2013 and based in San Francisco, the company develops the Evolution3 drone, designed for real-time data collection and analysis. Skycatch’s offerings include the Commander app, which allows users to operate the drone, and the Skycatch Dashboard, a software platform for data analysis and collaborative viewing. The company utilizes a blend of advanced hardware, software, and artificial intelligence to provide high-precision data rapidly and efficiently. In addition to its core products, Skycatch offers engineering support, training, and integration services, positioning itself as a leader in industrial data collection and analytics.
BookBub is a rapidly growing startup launched by serial entrepreneurs and run by a team gathered from the publishing and tech industries. Every day millions of readers use our service to discover great books, and thousands of leading publishers and authors work with us to drive sales and find new fans. Connecting readers with great deals on ebooks is just the beginning for BookBub. The rise of digital publishing is altering the way books are found, purchased, and read. We’re expanding our team to help address the challenges and opportunities of the publishing industry while continuing to help readers find books and authors they’ll love.
Otonomy, Inc. is a biopharmaceutical company based in San Diego, California, specializing in the development and commercialization of therapeutics for ear-related diseases and disorders. The company offers OTIPRIO, a ciprofloxacin otic suspension designed for use during tympanostomy tube placement surgery in pediatric patients. Otonomy is advancing several product candidates, including OTIVIDEX, a sustained-exposure formulation of dexamethasone for treating Ménière’s disease; OTO-313, aimed at treating tinnitus; and OTO-413, which targets cochlear synaptopathy and speech-in-noise hearing difficulties. Additionally, the company is developing OTO-510, an otoprotectant intended to prevent cisplatin-induced hearing loss, and OTO-6XX, which aims to induce hair cell regeneration for severe hearing loss. Otonomy leverages a proprietary formulation platform that allows for sustained drug exposure from a single administration, positioning itself as a leader in localized drug delivery for otic disorders. Founded in 2008, Otonomy focuses its operations primarily in the United States.
Synthorx, Inc. is a biopharmaceutical company specializing in the development of innovative protein therapeutics using advanced synthetic biology techniques. Founded in 2014 and headquartered in La Jolla, California, Synthorx focuses on its proprietary Synthorin programs aimed at treating cancer and autoimmune disorders. Its lead product candidate, THOR-707, is a modified form of recombinant human IL-2, currently being evaluated for various solid tumors both as a standalone treatment and in combination with immune checkpoint inhibitors. The company also develops Synthorins targeting IL-2 for autoimmune conditions, IL-10 for immuno-oncology applications, and IL-15 for regulating immune responses. Synthorx leverages a unique platform that enables the incorporation of synthetic DNA base pairs to enhance the specificity and efficacy of its protein therapeutics, thus offering improved treatment options for patients. Previously known as Alinos, Inc., the company acquired exclusive rights to its synthetic biology technology based on groundbreaking research from The Scripps Research Institute. As of January 2020, Synthorx operates as a subsidiary of Sanofi.
Indix is a provider of product information management services that aims to assist businesses and developers in making informed decisions and enhancing sales. The company has developed a Products Platform that integrates artificial intelligence with an extensive collection of product data, including price, availability, and seller information, along with unique identifiers and attributes. This platform enables organizations to improve the size and quality of their digital product catalogs, while also offering tools for big data analytics and visualizations. By leveraging these capabilities, Indix helps clients optimize their product portfolios and increase operational efficiency.
Sidecar Technologies operates a B2B delivery transportation network that connects retailers with customers through a fleet of everyday drivers using their personal vehicles. Founded in San Francisco in 2011, Sidecar focuses on creating a convenient and affordable transportation solution powered by pre-vetted drivers who can choose when to offer rides. The company emphasizes safety through a comprehensive system that includes background checks, rating systems for both drivers and riders, GPS tracking, and real-time trip sharing. Currently, Sidecar operates in ten major U.S. cities and has facilitated over half a million rides, demonstrating its commitment to enhancing the delivery and driving experience.
Empyr, Inc. is a San Diego-based company that operates an online-to-offline advertisement platform designed to connect digital engagement with real-world purchases. Established in 2011, Empyr specializes in card-linked offers, enabling national brands and digital publishers to track online advertisements that lead to offline sales. By integrating directly with major credit card associations, Empyr allows consumers to earn cashback at offline merchants simply by using their debit or credit cards. This platform provides a seamless experience for users while offering publishers the ability to generate revenue from each purchase and allowing merchants to link offline sales to specific online marketing efforts. Empyr collaborates with a diverse range of partners, including notable names in technology, banking, and hospitality, thereby tapping into the significant potential of the $3 trillion offline commerce market driven by online activity. The company has raised $35 million through its parent organization, Mogl, and currently employs 60 individuals.
MOGL is a restaurant rewards application dedicated to combating hunger in the United States. Members can earn 10% cash-back at thousands of participating restaurants by using a linked credit or debit card for their payments. Shortly after making a purchase, members receive an alert that allows them to donate a portion or the entirety of their cash-back to a local food bank. The app features a Hunger Tracker, enabling users to monitor the impact of their donations in their communities and engage in friendly competition with friends to see who can contribute the most meals. Founded in 2010, MOGL is headquartered in Solana Beach, California.
Quippi
Venture Round in 2014
Quippi Corporation is an international shopping card company based in La Jolla, California, founded in 2012. It specializes in providing fee-free international gift cards that can be purchased in the United States and redeemed in Mexico at various retailers. Quippi's product allows users to send gift cards to friends or family members in Mexico, enabling them to shop without incurring any fees, commissions, or hidden charges. Customers can easily purchase these gift cards online or in retail stores and share the Quippi PIN code with recipients via text, email, or phone. The cards are accepted at multiple retail partners in Mexico, which offer a wide range of products, including groceries, clothing, and home goods. Quippi aims to expand its network of retail partners in Mexico and intends to broaden its reach across Latin America and beyond. As of October 2015, Quippi operates as a subsidiary of EMIDA Technologies, Inc.
Chartio
Venture Round in 2014
Chartio is a business intelligence platform focused on democratizing data access and analysis for users without technical expertise. Founded in June 2010 by Dave Fowler and Daniel Levine, the company is headquartered in San Francisco, California. Chartio offers a cloud-based solution that enables users to connect various data sources, create interactive dashboards, and visualize data in real-time with a simple drag-and-drop interface. This approach eliminates the need for extensive SQL knowledge and data warehousing, allowing businesses to efficiently query and analyze their data. By facilitating the exploration of trends, patterns, and outliers, Chartio empowers organizations to make informed decisions and drive growth.
Avelas Biosciences
Series B in 2014
Avelas Biosciences is focused on advancing cancer surgery through innovative intraoperative imaging technology. The company has developed a proprietary platform that utilizes activatable cell-penetrating peptides to provide real-time diagnosis of metastatic nodes during surgical procedures. This technology enables oncologic surgeons to create a luminous map of the surgical area, improving their ability to identify and remove cancerous tissue effectively. By enhancing surgical precision, Avelas Biosciences aims to reduce the need for repeat surgeries and ultimately improve patient outcomes, establishing a new standard of care in oncological surgery.
Simulmedia
Series D in 2013
Simulmedia Inc. is a technology company based in New York with an additional location in San Francisco, specializing in a digital advertisement targeting platform for linear television. Founded in 2008, Simulmedia has established itself as a leader in cross-channel TV advertising through its TV+ platform, which enables advertisers to effectively reach audiences across both linear and connected TV. The company utilizes a data-driven approach, leveraging predictive analytics through its VAMOS platform to optimize TV ad placement and measurement. By combining the agility of digital advertising with the broad reach of television, Simulmedia provides marketers, agencies, and media owners with tools to conduct efficient marketing campaigns, assess outcomes, and receive optimization recommendations in near-real time.
Sitari Pharmaceuticals
Series A in 2013
Sitari Pharmaceuticals is a operator of a biotechnology company intended to develop treatments for multiple disease indications with an initial focus in celiac disease.
Redbooth is a cloud-based task and project management platform that facilitates team collaboration by offering a centralized space for shared tasks, discussions, and file sharing. Founded in 2008 and headquartered in Palo Alto, California, the platform is designed to enhance productivity through features such as project management templates, real-time communication, and integration with various tools like Slack, Outlook, and Dropbox. Redbooth serves a diverse range of sectors, including marketing, finance, education, and legal services, and is utilized by over 400,000 organizations worldwide, including notable companies and institutions such as AT&T, BBC, and Harvard University. The platform is accessible on mobile, desktop, and smart devices, making it adaptable for remote and in-office teams.
Otonomy, Inc. is a biopharmaceutical company based in San Diego, California, specializing in the development and commercialization of therapeutics for ear-related diseases and disorders. The company offers OTIPRIO, a ciprofloxacin otic suspension designed for use during tympanostomy tube placement surgery in pediatric patients. Otonomy is advancing several product candidates, including OTIVIDEX, a sustained-exposure formulation of dexamethasone for treating Ménière’s disease; OTO-313, aimed at treating tinnitus; and OTO-413, which targets cochlear synaptopathy and speech-in-noise hearing difficulties. Additionally, the company is developing OTO-510, an otoprotectant intended to prevent cisplatin-induced hearing loss, and OTO-6XX, which aims to induce hair cell regeneration for severe hearing loss. Otonomy leverages a proprietary formulation platform that allows for sustained drug exposure from a single administration, positioning itself as a leader in localized drug delivery for otic disorders. Founded in 2008, Otonomy focuses its operations primarily in the United States.
Conjur is a developer of security software designed to support enterprises in automating their infrastructure while ensuring robust identity and access management. The company offers a platform that enables organizations to identify, authorize, and audit all service and user identities across various environments, including public and hybrid clouds, virtual machines, and containers. By focusing on the automation of machine identity provisioning, privileged access authorization, and service account control, Conjur addresses the critical operational and compliance challenges faced by businesses in highly automated software delivery processes. The platform enhances security by providing real-time monitoring and detailed activity reports, which are essential for compliance and security audits. With a growing emphasis on safeguarding sensitive IT systems amidst rising security threats, Conjur delivers vital infrastructure solutions that allow enterprises to adopt modern IT practices confidently. Its clientele includes notable organizations such as Discovery Communications, AOL, and Cisco.
Happy Cloud
Series A in 2013
Happy Cloud, Inc. is a technology company founded in 2009 and headquartered in New York, with an additional location in Beit Shemesh, Israel. The company specializes in developing a cloud-based gaming platform that allows users to play games on demand, streamlining the gaming experience by eliminating lengthy download times. Utilizing patented technology, Happy Cloud pre-installs and pre-packages games on its network, allowing for immediate access without the need for installation on the user's device. This innovative approach avoids server-side rendering and video streaming, ensuring a lag-free experience that mirrors the performance of traditional game installations. Happy Cloud's platform is designed to deliver scalable and efficient gaming solutions, making it a pioneering force in the on-demand digital distribution of video games.
Cloudant is a provider of distributed database-as-a-service (DBaaS) that enables developers of web and mobile applications to concentrate on product development without the complexities of database management and scaling. Founded in 2008 in Cambridge, Massachusetts, by three physicists from MIT, Cloudant was born out of a need for better tools to manage and analyze large datasets encountered in their research. The company built a fault-tolerant and globally scalable data layer on top of Apache CouchDB, addressing the challenges of handling Big Data. Since its inception, Cloudant has expanded its services and now supports thousands of developers and numerous clients worldwide by managing and serving application data efficiently.
Nanigans is a Boston-based company that specializes in advertising automation software, designed to support in-house performance marketing teams. As a Software-as-a-Service provider, Nanigans offers a platform that features programmatic media buying, predictive revenue optimization, and real-time business intelligence. This comprehensive approach allows clients to enhance their advertising strategies and optimize revenue generation across various digital channels. In addition to its headquarters in Boston, Nanigans has established offices in New York, San Francisco, Seattle, London, Sydney, and Singapore, reflecting its global reach and commitment to serving a diverse client base.
Indix is a provider of product information management services that aims to assist businesses and developers in making informed decisions and enhancing sales. The company has developed a Products Platform that integrates artificial intelligence with an extensive collection of product data, including price, availability, and seller information, along with unique identifiers and attributes. This platform enables organizations to improve the size and quality of their digital product catalogs, while also offering tools for big data analytics and visualizations. By leveraging these capabilities, Indix helps clients optimize their product portfolios and increase operational efficiency.
Proximal Data
Series B in 2013
Proximal Data specializes in server-side caching solutions tailored for virtualized environments. The company's flagship product, AutoCache, enhances the performance of virtual machines by eliminating input/output bottlenecks through adaptive I/O caching. This technology allows for a significant increase in virtual machine density, facilitating more efficient use of server resources. When integrated with PCIe flash cards or solid-state drives from partner companies, Proximal Data's virtual cache optimizes the performance of virtualized servers while ensuring minimal disruption to IT operations. The company's innovative approach addresses the challenges associated with virtual server infrastructure, enabling organizations to achieve better efficiency and performance in their data management efforts.
Tapad Inc., established in 2010, is a global marketing technology company headquartered in New York with offices worldwide. It specializes in providing identity-based marketing solutions, primarily its proprietary Tapad Graph. This technology integrates billions of data points to understand consumer behavior across various devices, enabling publishers and advertisers to engage consumers more effectively and personalize campaigns at scale. Tapad's offerings include The Tapad Customer Data Platform for managing first-party data, Device Graph Access for targeting workflows, Applied Analytics suite for campaign performance tracking, and Dynamic Audiences for precise cross-device targeting. Serving agency trading desks, publishers, marketing technology companies, and Fortune 500 brands, Tapad operates as a subsidiary of Experian plc since November 2020.
Simulmedia
Series C in 2013
Simulmedia Inc. is a technology company based in New York with an additional location in San Francisco, specializing in a digital advertisement targeting platform for linear television. Founded in 2008, Simulmedia has established itself as a leader in cross-channel TV advertising through its TV+ platform, which enables advertisers to effectively reach audiences across both linear and connected TV. The company utilizes a data-driven approach, leveraging predictive analytics through its VAMOS platform to optimize TV ad placement and measurement. By combining the agility of digital advertising with the broad reach of television, Simulmedia provides marketers, agencies, and media owners with tools to conduct efficient marketing campaigns, assess outcomes, and receive optimization recommendations in near-real time.
LoopIt is an online shopping platform that enhances the shopping experience by facilitating one-on-one conversations between users and their friends or experts. By connecting individuals for reviews and opinions throughout the entire purchasing journey—from product discovery to the point of purchase and beyond—LoopIt aims to make online shopping more enjoyable and interactive. The company focuses on building a supportive community where users can share their insights and experiences, helping others make informed decisions while also receiving valuable advice.
Cheezburger
Venture Round in 2012
Cheezburger, Inc. is a Seattle-based company that operates a network of social humor websites, including popular platforms such as I Can Has Cheezburger, FAIL Blog, Know Your Meme, and Memebase. Founded in September 2007 by Ben Huh and Eric Nakagawa, the company specializes in providing social humor and entertainment content, allowing users to view, create, and remix memes, images, and videos. In addition to its extensive digital humor offerings, Cheezburger also provides advertising services to generate revenue. The company has published several books that compile humorous content from its platforms, further extending its brand into print media. Cheezburger operates as a subsidiary of Literally Media.
Avelas Biosciences
Series A in 2012
Avelas Biosciences is focused on advancing cancer surgery through innovative intraoperative imaging technology. The company has developed a proprietary platform that utilizes activatable cell-penetrating peptides to provide real-time diagnosis of metastatic nodes during surgical procedures. This technology enables oncologic surgeons to create a luminous map of the surgical area, improving their ability to identify and remove cancerous tissue effectively. By enhancing surgical precision, Avelas Biosciences aims to reduce the need for repeat surgeries and ultimately improve patient outcomes, establishing a new standard of care in oncological surgery.
Kaltura Inc. is a video platform provider serving a diverse range of sectors, including enterprises, media companies, service providers, and educational institutions. Founded in 2006 and based in New York, the company offers a comprehensive Video Experience Cloud that includes live, real-time, and on-demand video products. Its solutions encompass a variety of applications such as corporate training, video marketing, and virtual classroom environments, with specialized services tailored for educational and media sectors. Kaltura's platform supports multiple deployment options, including Software-as-a-Service and on-premise solutions, catering to a global clientele that engages hundreds of millions of viewers across various contexts, including communication, collaboration, and entertainment. The company primarily generates revenue from its Enterprise, Education, and Technology segment, with a significant portion coming from the United States.
PingUP is a Boston-based tech company that facilitates real-time scheduling between consumers and local businesses nationwide. Its platform enables over 30,000 businesses across 200 categories to receive bookings via directories and listings providers, with thousands more joining monthly. PingUP's mobile API allows seamless integration of "book it now" functionality on various websites and apps, enhancing consumer convenience. Backed by Avalon Ventures, the company is headquartered in Boston's Innovation District.
Proximal Data
Series A in 2012
Proximal Data specializes in server-side caching solutions tailored for virtualized environments. The company's flagship product, AutoCache, enhances the performance of virtual machines by eliminating input/output bottlenecks through adaptive I/O caching. This technology allows for a significant increase in virtual machine density, facilitating more efficient use of server resources. When integrated with PCIe flash cards or solid-state drives from partner companies, Proximal Data's virtual cache optimizes the performance of virtualized servers while ensuring minimal disruption to IT operations. The company's innovative approach addresses the challenges associated with virtual server infrastructure, enabling organizations to achieve better efficiency and performance in their data management efforts.
Selectable Media
Series A in 2012
Selectable Media Inc. is a company specializing in video advertising solutions that connect brands with engaged audiences. The firm offers innovative services for advertisers, including Selectable Value Exchange, which allows audiences to access content in exchange for interacting with brands, and Selectable Sponsored Stories, which seamlessly integrate branded video content in relevant contexts. For publishers, Selectable Media provides tools like Content-Unlock and Value Exchange, enabling consumers to access content by engaging with advertisements or subscribing. The company's platform supports a diverse range of publisher partners, such as newspapers, magazines, and various online services, including social media, mobile games, and sports trivia applications. By facilitating consumer interactions with brand advertising, Selectable Media helps publishers effectively monetize their content while providing advertisers with targeted audience access. Founded in 2005 and based in New York, Selectable Media was previously known as Nabbr.com Corp. and rebranded in May 2007.
Shelby.tv
Series A in 2012
Shelby TV is a platform designed to enhance the discovery and enjoyment of web videos. Through its app, available in the App Store, Shelby TV curates a personalized channel of videos sourced from popular platforms such as YouTube, Vimeo, Hulu, and others, as well as content shared by users on social networks like Twitter, Tumblr, and Facebook. The service utilizes user preferences to refine and improve its video recommendations over time, ensuring that users receive tailored content that aligns with their interests. By combining various sources and leveraging social sharing, Shelby TV aims to deliver an engaging video entertainment experience.
Kinvey, Inc. is a Boston-based company that provides a mobile backend as a service (mBaaS) platform designed to simplify the development of cloud backends for mobile, tablet, and web applications. Established in 2008, Kinvey enables developers and enterprises to focus on building their applications without the complexities of managing backend infrastructure. The platform automates the generation of APIs for accessing data, allowing developers to connect seamlessly to various cloud services and enterprise systems. Kinvey's solutions cater to diverse sectors, including healthcare, financial services, energy, and retail, by offering capabilities such as data storage, identity management, push notifications, and analytics. As of 2017, Kinvey operates as a subsidiary of Progress Software Corporation.
Backupify
Series C in 2012
Backupify, now part of Datto, specializes in cloud-to-cloud backup solutions designed to safeguard businesses' cloud-based data. The company's software offers features such as data retention and protection against ransomware and service outages, ensuring that critical business information remains accessible and secure. Backupify caters to IT professionals by providing the necessary tools to prevent data loss due to user errors, external attacks, and other disruptions, thereby enabling both end users and administrators to operate with confidence in their data's safety.
Byliner is a digital publishing company based in San Francisco, California, that collaborates directly with writers to deliver engaging short stories designed to be read in two hours or less. These e-shorts can be purchased individually through major digital bookstores, while subscribers gain access to a curated selection of premium content from a community of invited authors. This exclusive library features thousands of rarely-seen stories, enriching the reading experience. Byliner's offerings include insightful articles that cover various topics such as books, communication, and personal development, empowering readers to enhance their skills and express themselves more effectively in diverse situations.
Cardeas Pharma
Series A in 2012
Cardeas Pharma is focused on developing an innovative antibiotic formulation that combines two drugs to target highly resistant Gram-negative bacilli, such as Pseudomonas aeruginosa and Acinetobacter baumannii, as well as carbapenem-resistant Enterobacteriaceae. This formulation is designed to treat serious respiratory infections in critical care settings, particularly those caused by antibiotic-resistant organisms. Additionally, it demonstrates efficacy against Gram-positive pathogens, including methicillin-resistant Staphylococcus aureus (MRSA), and has activity on biofilms. The delivery system utilizes a single-patient use, vibrating-plate nebulizer compatible with all ventilators, which generates small, uniform aerosol droplets that effectively reach the small airways and alveoli. By integrating this novel antibiotic formulation with advanced drug-delivery technology, Cardeas Pharma aims to achieve substantial clinical improvements over current treatment standards.