Kentucky Science and Technology Corporation (KSTC)

Kentucky Science and Technology Corporation (KSTC) is a private, nonprofit organization dedicated to driving the progress of science, technology, and innovative economic development rooted in Kentucky expertise. Since its establishment in 1987, KSTC has been known for spearheading initiatives in education, economic competitiveness, and scientific research. Governed by a Board of Directors composed of industry, education, and government leaders, KSTC operates as a dynamic leader in advancing Kentucky's technological landscape.

55 past transactions

EdjAnalytics

Series A in 2020
EdjAnalytics specializes in predictive modeling techniques aimed at enhancing data analytics for businesses across various sectors, including healthcare, education, athletics, and commodities markets. The company offers a robust analytics platform that provides actionable insights, helping organizations eliminate uncertainty and optimize revenue. By leveraging a decision model that incorporates business and organizational context, EdjAnalytics identifies all potential outcomes based on existing data sets. This empowers clients to make informed and impactful decisions, ultimately improving their operational effectiveness and strategic planning.

GoWild

Seed Round in 2019
GoWild is a social commerce platform tailored for outdoor enthusiasts, combining a robust social network with an e-commerce engine. Founded in 2017 and headquartered in Louisville, Kentucky, the platform allows users to share their outdoor experiences while shopping for gear from an extensive marketplace that features hundreds of thousands of products. It also offers tools for tracking various outdoor activities such as hiking, scouting, hunting, and archery, enabling users to connect with like-minded individuals and brands. By fostering community engagement, GoWild effectively serves the needs of consumers passionate about outdoor adventures.

Xometry

Series C in 2018
Xometry Inc. is a provider of on-demand manufacturing services, specializing in various advanced production techniques, including 3D printing, CNC machining, injection molding, and urethane casting. Established in 2013 and headquartered in Gaithersburg, Maryland, with an additional office in Bethesda, the company operates an AI-enabled marketplace that facilitates the efficient sourcing of custom-manufactured parts and assemblies. Xometry's diverse offerings include rapid prototyping, volume production, mechanical assembly, and aftermarket solutions, catering to a wide range of clients, including engineers, product designers, and business owners. The company has a strategic partnership with Roush Yates Manufacturing Solutions, further enhancing its capabilities in the manufacturing sector. Xometry is organized into U.S. and International segments, with the majority of its revenue generated from the U.S. market.

Cloverleaf.me

Pre Seed Round in 2018
Cloverleaf LLC offers a visualization and scenario-planning platform designed to enhance team management and employee development. Founded in 2015 and based in Covington, Kentucky, the platform analyzes employee data to provide insights into team dynamics by cross-mapping personality traits, skills, and organizational culture. This enables users, including agile practitioners, project managers, and human resource professionals, to position team members effectively, improve communication, and identify suitable candidates to boost productivity. Additionally, Cloverleaf's automated coaching features deliver personalized nudges through commonly used tools like Google Workspace, Microsoft Outlook, and Slack, fostering collaboration and performance improvements within teams.

BehaVR

Seed Round in 2018
BehaVR, LLC is a healthcare technology company founded in 2016 and based in Elizabethtown, Kentucky. The company specializes in developing digital therapeutics that leverage virtual reality to address behavioral health challenges, particularly in the context of chronic diseases. BehaVR's platform aims to enhance skills such as stress resilience, emotional regulation, and self-efficacy, enabling individuals to better manage their conditions, adhere to treatment plans, and ultimately improve their overall health outcomes. Through its innovative approach, BehaVR seeks to bridge the gap between behavioral health and chronic disease management.

Switcher Studio

Seed Round in 2018
Switcher Studio is a mobile video application that enables users to synchronize multiple iPhones and iPads for recording and live streaming video to platforms such as YouTube and Ustream. The application includes a suite of live production tools that allow content creators to utilize their mobile devices as portable video mixers, facilitating the capture of video from various angles. Additionally, Switcher Studio offers features such as the ability to insert photos and graphic overlays, manage multi-view effects, and enhance audience engagement. This platform is designed to support users in creating dynamic and interactive live video content.

Podchaser

Pre Seed Round in 2018
Podchaser LLC, established in 2016 and based in Louisville, Kentucky, operates a comprehensive podcast database platform designed for discovery and engagement. The company's service enables users to search, review, follow podcasts, creators, lists, and other users, providing personalized updates. It offers features like custom podcast lists, creator profile pages, episode ratings, and integrations with existing podcast players, fostering interaction between listeners and podcasters while expanding audience reach.

Onovative

Venture Round in 2017
Onovative, LLC is a provider of comprehensive marketing software tailored for banks and credit unions, based in Louisville, Kentucky. The company offers two main products: Core iQ, which automates various customer communication channels such as email, postcards, SMS text, and phone calls for onboarding and marketing campaigns, and Base iQ, an intelligent survey platform that allows clients to create and manage surveys while benchmarking results against industry averages. By integrating its solutions with core banking systems, Onovative enables financial institutions to enhance customer relationships through automated onboarding, targeted marketing, cross-selling initiatives, and customer feedback collection. Established in 2012 and originally named Bank On Software LLC, Onovative rebranded in 2014 and currently operates as a subsidiary of Main Street Inc.

FlyWire

Seed Round in 2017
FlyWire is a company specializing in video technology that provides innovative solutions for the fishing industry. Their patented platform enables at-sea verification of sustainable fishing practices by translating video data into actionable insights. By working closely with fishers and seafood suppliers, FlyWire delivers electronic monitoring services that include onboarding, crew training, technical support, data retrieval, and reporting. This precision fishing platform enhances operational efficiency while minimizing monitoring costs. The company aims to promote more sustainable fishing practices and a transparent supply chain, contributing to the overall health of marine ecosystems. FlyWire is based in Honolulu, Hawaii.

PowerTech Water

Convertible Note in 2017
PowerTech Water, Inc. is a company that develops and markets innovative water treatment solutions, focusing on chemical-free technologies. Founded in 2014 and headquartered in Lexington, Kentucky, the company specializes in its flagship product, CapCo, an electrochemical filter designed to effectively remove various metals from water. PowerTech Water serves a diverse range of industries, including batteries, microelectronics, electroplating, automotive, metal finishing, mining, food and beverage, and oil and gas. The CapCo filter targets contaminants such as lead, copper, manganese, iron, silver, gold, mercury, zinc, nickel, and aluminum, aiming to provide efficient and sustainable solutions for wastewater management.

Revon Systems

Venture Round in 2017
Revon Systems is a developer of a platform for connecting physicians and patients. It offers a web platform that allows physicians to deliver care to patients remotely, specializes in helping patients with cardiovascular and lung conditions to self-manage signs and symptoms, intervene early on health decline that enables patients to manage their health and improve quality of life.

MobileServe

Seed Round in 2017
MobileServe LLC is a mobile application developer headquartered in Louisville, Kentucky, specializing in volunteer management for various organizations, including businesses, Greek organizations, non-profits, schools, and universities. Launched in 2015, MobileServe offers a platform that enables users to track, report, and measure their volunteer service hours and social impact within the community. The application allows users to record and verify their service activities, providing comprehensive reports that detail hours worked, dates, times, and locations. It also facilitates connections among users through features like leaderboards and event check-ins, while enabling the sharing of service stories via social media using photos and infographics. By streamlining the communication of social impact, MobileServe fosters greater engagement in volunteerism across diverse groups.

HANDLE Global

Venture Round in 2016
HANDLE Global specializes in transforming the healthcare capital equipment supply chain through innovative technology solutions. The company's flagship offering, Capital Cycle Management™, serves as an end-to-end operating system that enhances capital planning for healthcare providers, enabling them to make faster and more accurate decisions. HANDLE Global's platform also includes a B2B Marketplace, which facilitates access to a fully vetted secondary market for refurbished equipment. This marketplace simplifies the buying and re-marketing process with a single-login HAN Dashboard, allowing users to track savings and sales over time. By leveraging real-time fleet data and insights into equipment sales and planning, HANDLE Global supports healthcare systems in optimizing their operational efficiency and resource management.

Switcher Studio

Seed Round in 2016
Switcher Studio is a mobile video application that enables users to synchronize multiple iPhones and iPads for recording and live streaming video to platforms such as YouTube and Ustream. The application includes a suite of live production tools that allow content creators to utilize their mobile devices as portable video mixers, facilitating the capture of video from various angles. Additionally, Switcher Studio offers features such as the ability to insert photos and graphic overlays, manage multi-view effects, and enhance audience engagement. This platform is designed to support users in creating dynamic and interactive live video content.

FreshFry

Seed Round in 2016
FreshFry LLC, based in Louisville, Kentucky, specializes in frying oil purification solutions aimed at enhancing sustainability in commercial kitchens. Founded in 2014, the company offers innovative products such as the FreshFry porous pod cover and a cooking oil filtration pod. These products are designed to purify frying oil by capturing dissolved impurities, including free fatty acids and polar molecules, thereby extending the oil's life and improving its quality. By simplifying the process of oil filtration, FreshFry enables food businesses to maintain cleaner and brighter cooking oil, allowing them to concentrate on food preparation while promoting a more sustainable approach to cooking oil usage.

NX Development Corp.

Seed Round in 2016
NX Development Corp. is a life sciences company based in Lexington, Kentucky, focused on developing innovative solutions for neurosurgery. Incorporated in 2010, the company specializes in Gleolan (Aminolevulinic Acid Hydrochloride), an optical imaging agent designed to assist in the visualization of malignant tissue during surgery for patients with glioma. This product enhances the precision and extent of tumor resection while remaining cost-effective for hospitals and insurers, without adding new medical risks. As a subsidiary of photonamic GmbH & Co. KG, NX Development Corp. aims to support neurosurgeons by integrating Gleolan with existing fluorescence add-on kits from leading surgical microscope manufacturers, thereby improving surgical outcomes in the treatment of Glioblastoma.

MakeTime

Series A in 2016
MakeTime Inc. operates an online platform that connects purchasers of machined components with suppliers of computer numerical control (CNC) machine services. Founded in 2014 and based in Lexington, Kentucky, MakeTime collects unused CNC machine time from qualified machine shops across the United States and matches orders with the appropriate suppliers. The platform allows users to upload parts, add them to a cart, and track production in real time, ensuring timely delivery of components. By streamlining the manufacturing process, MakeTime aims to eliminate inefficiencies, improve transparency, and simplify pricing for customers seeking immediate CNC machining capacity. In July 2018, MakeTime was acquired by Xometry Inc.

Smart Farm Systems

Venture Round in 2016
Smart Farm Systems, Inc. specializes in developing wireless monitoring and control systems tailored for agriculture. The company focuses on remotely located irrigation pumps, as well as soil moisture and water level monitoring devices. Utilizing radio frequency (RF) wireless technology, Smart Farm integrates smart sensors with pump modules to facilitate remote field monitoring and control. Its application allows users to oversee the status of their wells, crops, and local weather conditions, providing real-time, actionable insights that enhance decision-making for farmers. This innovative system enables precise irrigation, allowing farmers to apply the right amount of water at optimal times, which can lead to improved profitability. Founded in 2014, Smart Farm Systems is headquartered in Nicholasville, Kentucky, with an additional office in Jonesboro, Arkansas.

Sentry Health

Series A in 2015
SentryHealth is leading the charge in employee health and wellbeing. Our integrated health management solution is the perfect combination of technology and personalized support from caring medical professionals. Powered by AI, we analyze data from multiple sources to develop unique Intelligent Profiles complete with personalized recommendations. Pairing these profiles with smart technology and Registered Nurse Advocates, we engage with each employee to ensure they receive the right care at the right time. The result is better participation, higher satisfaction, greater outcomes, and lower costs.

Onovative

Series A in 2015
Onovative, LLC is a provider of comprehensive marketing software tailored for banks and credit unions, based in Louisville, Kentucky. The company offers two main products: Core iQ, which automates various customer communication channels such as email, postcards, SMS text, and phone calls for onboarding and marketing campaigns, and Base iQ, an intelligent survey platform that allows clients to create and manage surveys while benchmarking results against industry averages. By integrating its solutions with core banking systems, Onovative enables financial institutions to enhance customer relationships through automated onboarding, targeted marketing, cross-selling initiatives, and customer feedback collection. Established in 2012 and originally named Bank On Software LLC, Onovative rebranded in 2014 and currently operates as a subsidiary of Main Street Inc.

Hijro

Seed Round in 2015
Hijro operates as a financial operating network specifically designed for global trade, utilizing distributed ledger technology to enhance efficiency and security in trade finance. By connecting banks, buyers, and suppliers within a unified network, Hijro aims to streamline settlement processes, mitigate fraud risks, and eliminate costly data silos prevalent in the open-account trade market, which is valued at approximately $4 trillion. The Hijro Network serves as a foundational “fabric” for trade, offering a variety of applications and solutions, including a multi-bank, multi-lender trade asset marketplace and flexible working capital options for businesses. Additionally, Hijro provides APIs to facilitate seamless integration into its network, allowing financial institutions to tokenize, transfer, and trade various digital assets such as receivables and approved payables. Through these innovations, Hijro positions itself as a modern solution for the complexities of global trade.

WeStyle

Convertible Note in 2015
Introducing WeStyle – Style Made Social! WeStyle offers instant style feedback plus discovery options that shift style uncertainty into total outfit confidence. WeStyle provides unlimited access to a community of style-savvy individuals who are ready to help make your looks better than ever. With WeStyle, you can: EXPRESS YOURSELF by designing your profile to reflect your taste with personal style types, brand favorites, personal blog/social handle information, and a customizable cover image. MAKE YOUR UPLOADS TOTALLY UNIQUE using our new filters and easy-to-use cropping tool GET THE STYLE GUIDANCE YOU’RE REALLY LOOKING FOR – Share your looks (in batches, or one-by-one) to a responsive, fashionable community with a style question and receive real-time advice with instant push notifications. - Need help on a single look? Share your style and receive “Yes” or “No” votes with helpful comments - Can’t decide between several different looks? Share multiple looks in a single post and receive let the community decide which look is best GIVE STYLE GUIDANCE – Give back to the helpful community by giving your own advice! Show off your eye for style to help other users by providing your opinion on looks posted to a rolling feed INSPIRE AND BE INSPIRED - Know your look is killing it and want to inspire others? Share one or multiple looks and receive likes - no votes necessary - Share the details of what you’re wearing - when sharing a look, tag the image with the brand, item type, size, color, and more DISCOVER WHAT’S NEW with our tailored-to-you Discovery Feed. Browse popular looks based on your unique style preferences - the more you use the app, the more “you” your suggestions will be! - If you have something already in mind - a brand, a style, a trending hashtag, WeStyle’s search feature will help you find it in a snap SUGGEST PRODUCTS – Guide others to over 1,000,000 of the latest styles and brands that you think might work for them

Revon Systems

Venture Round in 2015
Revon Systems is a developer of a platform for connecting physicians and patients. It offers a web platform that allows physicians to deliver care to patients remotely, specializes in helping patients with cardiovascular and lung conditions to self-manage signs and symptoms, intervene early on health decline that enables patients to manage their health and improve quality of life.

NX Prenatal

Series A in 2014
NX Prenatal Inc. is a molecular diagnostics company focused on developing diagnostic assays that address adverse pregnancy conditions, particularly preterm birth. The company utilizes its proprietary NeXosome platform, which allows for the advanced isolation and enrichment of exosome and microvesicle particles from bodily fluids, facilitating non-invasive biomarker evaluation. This technology is aimed at detecting and managing pregnancy-related complications, enabling healthcare professionals to intervene effectively and minimize risks for both mothers and their children. NX Prenatal, established in 2013 and headquartered in Louisville, Kentucky, also operates a laboratory in Bellaire, Texas. The company has formed strategic partnerships with NxGEN MDx and Thermo Fisher Scientific to enhance its offerings. NX Prenatal operates as a subsidiary of NX PharmaGen Inc.

Tixers

Seed Round in 2013
Tixers is changing the way tickets are exchanged. With Tixers, you can exchange tickets you're unable to use now for tickets you can use in the future. Ticket holders receive instant credit for their tickets and can use those credits for other sporting events or concerts. Those who do not have credits on the site can name the game they want to go to and purchase tickets as well. Millions of tickets go unused each year and Tixers is trying to eliminate this problem. Tixers is different than competitors like Stubhub because Tixers guarantees some value immediately and is aiming to create a network that allows ticket holders, primarily season ticket holders, to "share" tickets among one another. Tixers primary customer are corporations and small businesses that purchase season tickets that they often let go unused. Revenue is generated through processing fees when sellers redeem tickets (similar to frequent flyer mile redemption fees) and on a spread based upon demand.

Liberate Medical

Grant in 2013
Liberate Medical, LLC is a medical device company focused on improving the treatment of patients with chronic obstructive pulmonary disease (COPD) by developing innovative technologies. Founded in 2013 and based in Crestwood, Kentucky, the company has created VentFree, a system that utilizes non-invasive neuromuscular electrical stimulation to contract abdominal wall muscles in sync with a patient’s breathing. This approach aims to minimize disuse atrophy of these muscles, potentially decreasing the duration of mechanical ventilation required for adult patients. By enhancing respiratory muscle function, Liberate Medical seeks to improve patient outcomes and reduce healthcare costs associated with pulmonary disorders.

Apellis Pharmaceuticals

Venture Round in 2013
Apellis Pharmaceuticals Inc., established in 2009, is a clinical-stage biopharmaceutical company based in Waltham, Massachusetts. The company specializes in developing therapeutic compounds that inhibit the complement system, focusing on autoimmune and inflammatory diseases with high unmet needs. Its lead product candidate, pegcetacoplan, is currently in Phase III trials for treating geographic atrophy in age-related macular degeneration and paroxysmal nocturnal hemoglobinuria, and in Phase II trials for various kidney and blood disorders. Additionally, Apellis is developing APL-9 for preventing immune system activation during adeno-associated virus administration. The company collaborates with Swedish Orphan Biovitrum AB (publ) to advance pegcetacoplan for treating multiple rare diseases.

NX PharmaGen

Debt Financing in 2013
NX PharmaGen Inc. is a biotechnology company based in Louisville, Kentucky, focused on developing blood-based diagnostic products aimed at improving surgical outcomes for cancer and other diseases. Founded in 2010, the company offers a range of diagnostic solutions, including the NeXosome prenatal and oncology diagnostics, as well as a fluorescence-guided resection imaging agent. Its lead technology, the NeXosome Platform, utilizes proteomics to analyze microvesicles released from placental, tumor, and diseased cells into the bloodstream. This innovative approach provides medical practitioners with actionable, disease-specific molecular data in a repeatable and cost-effective manner, facilitating timely and effective diagnosis of conditions such as preterm birth and cancer.

Sentry Health

Venture Round in 2013
SentryHealth is leading the charge in employee health and wellbeing. Our integrated health management solution is the perfect combination of technology and personalized support from caring medical professionals. Powered by AI, we analyze data from multiple sources to develop unique Intelligent Profiles complete with personalized recommendations. Pairing these profiles with smart technology and Registered Nurse Advocates, we engage with each employee to ensure they receive the right care at the right time. The result is better participation, higher satisfaction, greater outcomes, and lower costs.

Stadionaut

Grant in 2012
Based out of Lexington, KY from the accelerator of Awesome Inc., Stadionaut is a mobile application development firm. Currently developing the Crowded mobile application. Crowded engages sports fans and increases stadium revenue. This free application uses live interactive play prediction and trivia at baseball games to test the knowledge of competing viewers. Players are awarded accolades and offered the incentive of prizes for top scores, which will be tied into stadium concessions and prizes. The user interface allows fans of all ages and sports knowledge to play, while effectively delivering advertisements for team and stadium sponsors.

Apellis Pharmaceuticals

Series B in 2012
Apellis Pharmaceuticals Inc., established in 2009, is a clinical-stage biopharmaceutical company based in Waltham, Massachusetts. The company specializes in developing therapeutic compounds that inhibit the complement system, focusing on autoimmune and inflammatory diseases with high unmet needs. Its lead product candidate, pegcetacoplan, is currently in Phase III trials for treating geographic atrophy in age-related macular degeneration and paroxysmal nocturnal hemoglobinuria, and in Phase II trials for various kidney and blood disorders. Additionally, Apellis is developing APL-9 for preventing immune system activation during adeno-associated virus administration. The company collaborates with Swedish Orphan Biovitrum AB (publ) to advance pegcetacoplan for treating multiple rare diseases.

NX PharmaGen

Angel Round in 2012
NX PharmaGen Inc. is a biotechnology company based in Louisville, Kentucky, focused on developing blood-based diagnostic products aimed at improving surgical outcomes for cancer and other diseases. Founded in 2010, the company offers a range of diagnostic solutions, including the NeXosome prenatal and oncology diagnostics, as well as a fluorescence-guided resection imaging agent. Its lead technology, the NeXosome Platform, utilizes proteomics to analyze microvesicles released from placental, tumor, and diseased cells into the bloodstream. This innovative approach provides medical practitioners with actionable, disease-specific molecular data in a repeatable and cost-effective manner, facilitating timely and effective diagnosis of conditions such as preterm birth and cancer.

Equinext

Seed Round in 2011
Equinext, LLC develops technologies for the treatment of ligament and tendon injuries in horses in the United States. It offers nonsurgical exogenous crosslink therapy (NEXT), a chemically made device formed following injection of a crosslinking agent into the lesion of the tendon or ligament that interacts with the native proteins (collagen). The company’s products are also used to treat the causes of wobbler’s disease and intervertebral disc degradation. It has strategic partnership with Hagyard Equine Medical Institute. The company was incorporated in 2011 and is based in Lexington, Kentucky.

Apellis Pharmaceuticals

Series A in 2011
Apellis Pharmaceuticals Inc., established in 2009, is a clinical-stage biopharmaceutical company based in Waltham, Massachusetts. The company specializes in developing therapeutic compounds that inhibit the complement system, focusing on autoimmune and inflammatory diseases with high unmet needs. Its lead product candidate, pegcetacoplan, is currently in Phase III trials for treating geographic atrophy in age-related macular degeneration and paroxysmal nocturnal hemoglobinuria, and in Phase II trials for various kidney and blood disorders. Additionally, Apellis is developing APL-9 for preventing immune system activation during adeno-associated virus administration. The company collaborates with Swedish Orphan Biovitrum AB (publ) to advance pegcetacoplan for treating multiple rare diseases.

IF Technologies

Venture Round in 2011
IF Technologies specializes in providing analytics and transparency solutions tailored for the insurance and cost containment sectors within healthcare. The company has developed a pricing platform that enhances the clarity of data among healthcare entities. By utilizing comparative data, this platform enables subscribed insurers and organizations to access actual healthcare pricing information easily. This approach helps to measurably reduce healthcare costs by promoting transparency and informed decision-making.

Vivorte

Venture Round in 2010
Vivorte is a company based in Louisville, Kentucky, that specializes in the design and manufacture of orthopedic devices and bone graft substitutes. Founded in 2008, the company focuses on developing innovative solutions to enhance bone strength and facilitate healing for patients. Vivorte's product offerings include minimally invasive implantable devices aimed at reducing hip fractures, as well as synthetic and biologic bone void fillers. By utilizing regenerative technologies, Vivorte aims to improve surgical outcomes and advance the standard of care in orthopedic treatments.

Jacobs Automation

Seed Round in 2010
Jacobs Automation LLC is a developer of intelligent track motion control technology. Jacobs Automation, Inc., based in Erlanger, Ky., is known for its innovative and leading-edge iTRAK technology. The company’s focus is developing reliable and sustainable solutions for the automation industry.

Seikowave

Pre Seed Round in 2010
Seikowave, headquartered in Lexington, Kentucky, specializes in developing advanced measurement solutions for various sectors, including health care, security, and industrial applications. The company focuses on commercializing innovative technologies that enable high-speed, cost-effective 3D measurements, capable of generating point clouds with up to 350,000 points at rates of 1,000 point clouds per second. Utilizing expertise in digital signal processing, image processing, and optical systems, Seikowave's technology plays a vital role in applications ranging from automotive part measurement to pipeline inspection and dental restoration. Additionally, the company addresses challenges in the oil and gas industry by acquiring and analyzing 3D data to identify defects and anomalies, thus aiding in the determination of service fitness and guiding necessary repair procedures. Seikowave also manufactures hardware and software for general non-destructive testing applications.

Summit Biosciences

Seed Round in 2010
Summit Biosciences Inc. is a specialty pharmaceutical company based in Lexington, Kentucky, that specializes in the development, manufacturing, and commercialization of generic and innovative nasal spray drug products. Established in 2008, the company focuses on creating unit-dose, pre-filled, and disposable intranasal spray products aimed at addressing both chronic and acute care conditions. In addition to its own product development, Summit Biosciences offers contract development and manufacturing services, which include analytical development, testing, and regulatory support, catering to a diverse range of clients and partners in the pharmaceutical industry.

Apellis Pharmaceuticals

Venture Round in 2010
Apellis Pharmaceuticals Inc., established in 2009, is a clinical-stage biopharmaceutical company based in Waltham, Massachusetts. The company specializes in developing therapeutic compounds that inhibit the complement system, focusing on autoimmune and inflammatory diseases with high unmet needs. Its lead product candidate, pegcetacoplan, is currently in Phase III trials for treating geographic atrophy in age-related macular degeneration and paroxysmal nocturnal hemoglobinuria, and in Phase II trials for various kidney and blood disorders. Additionally, Apellis is developing APL-9 for preventing immune system activation during adeno-associated virus administration. The company collaborates with Swedish Orphan Biovitrum AB (publ) to advance pegcetacoplan for treating multiple rare diseases.

Allylix

Series C in 2010
Allylix, Inc. is an early-stage biotechnology company based in San Diego, California, with research and development laboratories in Lexington, Kentucky. Founded in 2002, the company specializes in developing terpene products and their derivatives for various markets, including flavor and fragrance, food ingredients, pharmaceuticals, agriculture, and biofuels. Notable among its offerings is nootkatone, a grapefruit flavor used in beverages such as fruit juices and citrus-flavored sodas. Additionally, Allylix works on sesquiterpenes that contribute to the aroma chemical segment of the flavor and fragrance industry, as well as production platforms for the pharmaceutical and nutraceutical sectors.

Hollison

Seed Round in 2009
Hollison, LLC is a company based in Owensboro, Kentucky, specializing in food safety and security solutions. Founded in 2005 and originally named Global Grain Security, LLC, Hollison develops advanced sampling technology that enables food manufacturers to detect and remediate pathogens within the food supply. The firm offers a proprietary web-based food tracking system that integrates with its sampling technologies, providing comprehensive chain-of-custody information alongside contamination test data. Hollison's services encompass the entire food supply chain, addressing the detection and identification of chemical, biological, and radiological contaminants in various food products, including raw commodities, processed foods, and beverages. Through its innovative products and services, Hollison aims to enhance food protection and ensure safety for consumers.

IF Technologies

Venture Round in 2009
IF Technologies specializes in providing analytics and transparency solutions tailored for the insurance and cost containment sectors within healthcare. The company has developed a pricing platform that enhances the clarity of data among healthcare entities. By utilizing comparative data, this platform enables subscribed insurers and organizations to access actual healthcare pricing information easily. This approach helps to measurably reduce healthcare costs by promoting transparency and informed decision-making.

SinglePipe Communications

Series B in 2009
SinglePipe Communications is the leading provider of residential and turnkey business class VoIP phone services for wholesale, channel resale and private label. Our solutions are:

Resonant Vibes

Venture Round in 2008
Resonant Vibes LLC operates as a music blog. It enables DJs and fans to browse through various music tracks and mixes, as well as facilitates producers to collect various music samples in uncompressed format. The company was incorporated in 2004 and is based in Louisville, Kentucky.

Bexion Pharmaceuticals

Seed Round in 2008
Bexion Pharmaceuticals, Inc. is a biotechnology company based in Covington, Kentucky, focused on developing biologic therapies for cancer. Established in 2006, the company is pioneering innovative treatments, notably BXQ-350, which employs a unique mechanism of action to target and eliminate tumor cells. This approach involves the identification of Phosphatidylserine patches found on tumor cells and neovasculature, leading to apoptosis through the activation of acid sphingomyelinase, resulting in ceramide generation and elevated caspase levels. Additionally, Bexion aims to address challenges like chemotherapy-induced peripheral neuropathy by programming cell death, reducing tumor proliferation, and stimulating the immune response.

Zynerba Pharmaceuticals

Seed Round in 2007
Zynerba Pharmaceuticals is a clinical-stage specialty pharmaceutical company focused on developing transdermal cannabinoid therapies for rare and near-rare neuropsychiatric disorders. The company's lead product, Zygel, is a patent-protected cannabidiol gel currently undergoing Phase II clinical trials for various conditions, including developmental and epileptic encephalopathies, autism spectrum disorder, pediatric behavioral symptoms associated with 22q11.2 deletion syndrome, and fragile X syndrome. Zynerba aims to utilize modern drug delivery technology to provide sustained and controlled cannabinoid delivery while minimizing adverse effects commonly associated with oral dosing. Founded in 2007 and headquartered in Devon, Pennsylvania, Zynerba was formerly known as AllTranz, Inc. and rebranded in August 2014.

US WorldMeds

Seed Round in 2006
US WorldMeds is a specialty pharmaceutical company based in Kentucky, focused on developing, licensing, and commercializing unique pharmaceuticals that address unmet medical needs. Founded in 2001 by CEO Paul Breckinridge "Breck" Jones, the company aims to create innovative treatments primarily for conditions such as Parkinson's disease, cervical dystonia, malignant hyperthermia, and other rare diseases. By leveraging local talent and expertise, US WorldMeds aspires to be a significant player in the pharmaceutical industry while maintaining its closely-held structure. The company is dedicated to improving the lives of patients and is committed to expanding its presence as a responsible corporate citizen, fostering innovation, and creating high-quality jobs in its headquarters in Louisville and its satellite offices and manufacturing facilities.

Potentia Pharmaceuticals

Seed Round in 2006
Potentia Pharmaceuticals is a biotechnology company, develops anti-inflammatory drugs/therapeutics.

RhinoCyte

Series A in 2006
RhinoCyte, Inc. is a biotechnology company based in Louisville, Kentucky, founded in 2005. The company specializes in developing and commercializing autologous adult olfactory-derived stem cell therapies aimed at treating various degenerative and traumatic neurological diseases. RhinoCyte's innovative technology focuses on the biopsy, harvesting, and processing of stem cells from the olfactory region of the nasal cavity, allowing for outpatient procedures that facilitate functional recovery without the need for immunosuppressive therapy. The therapies target conditions such as spinal cord injuries, Parkinson's disease, amyotrophic lateral sclerosis, multiple sclerosis, and Type 1 diabetes. RhinoCyte has established strategic partnerships with local organizations and institutions, enhancing its capabilities in advancing stem cell treatment options for patients.

Mersive Technologies

Series A in 2006
Mersive Technologies, Inc. is a provider of wireless media streaming and collaboration software tailored for corporate, education, and government sectors. The company's flagship product, Solstice, allows multiple users to connect wirelessly to shared displays from various devices, enhancing collaboration in meeting spaces. Accompanying Solstice is the Solstice Dashboard, which enables IT administrators to manage and monitor Solstice deployments effectively. Additionally, Mersive offers Solstice Discovery Services to facilitate secure connections to displays and Kepler, a cloud-based platform that provides analytics on meeting space usage and collaboration efficiency. Together, these solutions transform traditional conference rooms and classrooms into dynamic, interactive environments, fostering creativity and improving productivity. Founded in 2004 and based in Denver, Colorado, Mersive serves its customers through a network of authorized resellers.

Allylix

Series A in 2005
Allylix, Inc. is an early-stage biotechnology company based in San Diego, California, with research and development laboratories in Lexington, Kentucky. Founded in 2002, the company specializes in developing terpene products and their derivatives for various markets, including flavor and fragrance, food ingredients, pharmaceuticals, agriculture, and biofuels. Notable among its offerings is nootkatone, a grapefruit flavor used in beverages such as fruit juices and citrus-flavored sodas. Additionally, Allylix works on sesquiterpenes that contribute to the aroma chemical segment of the flavor and fragrance industry, as well as production platforms for the pharmaceutical and nutraceutical sectors.

Allylix

Venture Round in 2005
Allylix, Inc. is an early-stage biotechnology company based in San Diego, California, with research and development laboratories in Lexington, Kentucky. Founded in 2002, the company specializes in developing terpene products and their derivatives for various markets, including flavor and fragrance, food ingredients, pharmaceuticals, agriculture, and biofuels. Notable among its offerings is nootkatone, a grapefruit flavor used in beverages such as fruit juices and citrus-flavored sodas. Additionally, Allylix works on sesquiterpenes that contribute to the aroma chemical segment of the flavor and fragrance industry, as well as production platforms for the pharmaceutical and nutraceutical sectors.

Ceptaris Therapeutics

Series A in 2002
Ceptaris Therapeutics, Inc. is a privately held specialty pharmaceutical company focused on developing a proprietary gel formulation of mechlorethamine hydrochloride for treating early-stage (stages I-IIA) mycosis fungoides, a form of Cutaneous T-Cell Lymphoma (CTCL). If approved, this investigational drug would be the first topical mechlorethamine product available for managing the signs and symptoms of this rare cancer. In addition to this primary focus, Ceptaris is also involved in developing other therapeutic products, including YT-1006, an NMDA antagonist aimed at treating neuropathic pain while minimizing side effects associated with NMDA. The company's innovative approaches enable healthcare professionals to address both dermatological and central nervous system disorders effectively.
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