Battelle Ventures

Bionano Genomics, Inc. is a biotechnology company focused on genome mapping and analysis. It develops and markets the Saphyr system, an advanced platform designed for ultra-sensitive and specific detection of structural variations in DNA, such as insertions, deletions, and translocations, which are often linked to genetic disorders and diseases, including cancer. The Saphyr system employs optical genome mapping technology, allowing for direct visualization and analysis of long DNA molecules without relying on sequencing. This capability provides researchers and clinicians with critical insights into the structural variations within genomes, enhancing the understanding of disease mechanisms and supporting the development of personalized treatment strategies. Bionano Genomics also offers essential reagents and data solutions, including Bionano prep kits, labeling kits, and software tools for comprehensive experiment management. Its products are primarily sold to academic and governmental research laboratories, as well as pharmaceutical, biotechnology, and contract research organizations across multiple regions, including North America, Europe, and Asia. Founded in 2003 and headquartered in San Diego, California, the company was previously known as BioNano Genomics, Inc. until its name change in July 2018.

Bionano Genomics, Inc. is a biotechnology company focused on genome mapping and analysis. It develops and markets the Saphyr system, an advanced platform designed for ultra-sensitive and specific detection of structural variations in DNA, such as insertions, deletions, and translocations, which are often linked to genetic disorders and diseases, including cancer. The Saphyr system employs optical genome mapping technology, allowing for direct visualization and analysis of long DNA molecules without relying on sequencing. This capability provides researchers and clinicians with critical insights into the structural variations within genomes, enhancing the understanding of disease mechanisms and supporting the development of personalized treatment strategies. Bionano Genomics also offers essential reagents and data solutions, including Bionano prep kits, labeling kits, and software tools for comprehensive experiment management. Its products are primarily sold to academic and governmental research laboratories, as well as pharmaceutical, biotechnology, and contract research organizations across multiple regions, including North America, Europe, and Asia. Founded in 2003 and headquartered in San Diego, California, the company was previously known as BioNano Genomics, Inc. until its name change in July 2018.

Micro Interventional Devices, Inc., founded in 2010 and based in Newtown, Pennsylvania, is a medical device company specializing in disruptive technologies for percutaneous and minimally invasive structural heart repair procedures. The company designs and manufactures devices such as Permaseal, which facilitates transapical access and closure for catheter-based procedures, and Minimally Invasive Annuloplasty technology for tricuspid and mitral repair. Additionally, they offer Endovalve, a percutaneous mitral valve replacement system, and Permavalve, a percutaneous mitral valve with active fixation. Their proprietary technology focuses on soft-tissue anchoring and delivery devices, enabling off-pump procedures and transforming open surgical techniques into transcatheter procedures.

Proterro, Inc. is a company based in Princeton, New Jersey, founded in 2008, that specializes in the development and marketing of sugar feedstock. Unlike traditional methods that extract sucrose from crops or deconstruct cellulosic materials, Proterro produces a fortified sucrose known as PROTOSE sugar through the use of patented, highly productive microorganisms. This innovative approach creates a non-crop based, noncellulosic sugar feedstock that is ready for fermentation, allowing for the economical and scalable production of biofuels and biobased chemicals. By avoiding the price volatility associated with conventional feedstock markets, Proterro provides a stable and cost-effective solution for industrial applications in the fuels and chemicals sectors.

Bionano Genomics, Inc. is a biotechnology company focused on genome mapping and analysis. It develops and markets the Saphyr system, an advanced platform designed for ultra-sensitive and specific detection of structural variations in DNA, such as insertions, deletions, and translocations, which are often linked to genetic disorders and diseases, including cancer. The Saphyr system employs optical genome mapping technology, allowing for direct visualization and analysis of long DNA molecules without relying on sequencing. This capability provides researchers and clinicians with critical insights into the structural variations within genomes, enhancing the understanding of disease mechanisms and supporting the development of personalized treatment strategies. Bionano Genomics also offers essential reagents and data solutions, including Bionano prep kits, labeling kits, and software tools for comprehensive experiment management. Its products are primarily sold to academic and governmental research laboratories, as well as pharmaceutical, biotechnology, and contract research organizations across multiple regions, including North America, Europe, and Asia. Founded in 2003 and headquartered in San Diego, California, the company was previously known as BioNano Genomics, Inc. until its name change in July 2018.

Bionano Genomics, Inc. is a biotechnology company focused on genome mapping and analysis. It develops and markets the Saphyr system, an advanced platform designed for ultra-sensitive and specific detection of structural variations in DNA, such as insertions, deletions, and translocations, which are often linked to genetic disorders and diseases, including cancer. The Saphyr system employs optical genome mapping technology, allowing for direct visualization and analysis of long DNA molecules without relying on sequencing. This capability provides researchers and clinicians with critical insights into the structural variations within genomes, enhancing the understanding of disease mechanisms and supporting the development of personalized treatment strategies. Bionano Genomics also offers essential reagents and data solutions, including Bionano prep kits, labeling kits, and software tools for comprehensive experiment management. Its products are primarily sold to academic and governmental research laboratories, as well as pharmaceutical, biotechnology, and contract research organizations across multiple regions, including North America, Europe, and Asia. Founded in 2003 and headquartered in San Diego, California, the company was previously known as BioNano Genomics, Inc. until its name change in July 2018.

Nistica, Inc. is a developer and manufacturer of optical networking modules focused on delivering high-bandwidth applications. Established in January 2005 and headquartered in Bridgewater, New Jersey, the company specializes in agile optical modules designed for optical system original equipment manufacturers globally. Nistica's product offerings include reconfigurable optical add/drop multiplexer (ROADM) subsystems, low port-count wavelength selective switch modules, and high port-count series products. These solutions facilitate flexible channel plans and dynamic power equalization, enabling users to customize channel spacing. Additionally, Nistica provides advanced products such as FLEXBOX, a disaggregated ROADM node aimed at software-defined networks. The company's innovative approach simplifies and automates optical network delivery, enhancing the capabilities of both edge and metro core networks. In June 2012, Nistica was acquired by Molex Optical Solutions Group, further extending its reach and impact in the optical networking industry.

GRIDSMART Technologies develops traffic management systems for clients worldwide. Its flagship product, GRIDSMART, includes various solutions such as the Bell Camera for intersection and highway data collection, processors like the CPU/GRIDSMART processor and GS2 processor, and software modules for real-time data analysis and pedestrian tracking. The company also offers traditional zoom cameras and FLIR thermal cameras. GRIDSMART Technologies sells its products through distributors and direct sales teams in multiple countries, including the United States, Canada, Australia, Oman, and Ireland. Founded in 2006 and headquartered in Knoxville, Tennessee, the company was formerly known as Aldis, Inc. before changing its name in March 2015.

Nistica, Inc. is a developer and manufacturer of optical networking modules focused on delivering high-bandwidth applications. Established in January 2005 and headquartered in Bridgewater, New Jersey, the company specializes in agile optical modules designed for optical system original equipment manufacturers globally. Nistica's product offerings include reconfigurable optical add/drop multiplexer (ROADM) subsystems, low port-count wavelength selective switch modules, and high port-count series products. These solutions facilitate flexible channel plans and dynamic power equalization, enabling users to customize channel spacing. Additionally, Nistica provides advanced products such as FLEXBOX, a disaggregated ROADM node aimed at software-defined networks. The company's innovative approach simplifies and automates optical network delivery, enhancing the capabilities of both edge and metro core networks. In June 2012, Nistica was acquired by Molex Optical Solutions Group, further extending its reach and impact in the optical networking industry.

Hepregen Corporation is a biotechnology company focused on developing a bio-engineered micro-liver platform aimed at enhancing safety assessments and drug development. This innovative platform is utilized for various applications, including acute and chronic toxicity testing, drug metabolism studies, metabolite identification, toxicity screening, and evaluating drug-drug interactions. Hepregen's microliver technology also shows potential in drug discovery and disease modeling, addressing conditions such as obesity, infectious diseases, and diabetes. The company is engaged in industrial collaborations to validate and expand the applications of its technology across the pharmaceutical industry, targeting a combined market value of approximately one billion dollars annually.

Hepregen Corporation is a biotechnology company focused on developing a bio-engineered micro-liver platform aimed at enhancing safety assessments and drug development. This innovative platform is utilized for various applications, including acute and chronic toxicity testing, drug metabolism studies, metabolite identification, toxicity screening, and evaluating drug-drug interactions. Hepregen's microliver technology also shows potential in drug discovery and disease modeling, addressing conditions such as obesity, infectious diseases, and diabetes. The company is engaged in industrial collaborations to validate and expand the applications of its technology across the pharmaceutical industry, targeting a combined market value of approximately one billion dollars annually.

NuPathe Inc., a Pennsylvania-based specialty pharmaceutical company, specializes in developing and commercializing branded therapeutics for neurological and psychiatric disorders. Its primary product, Zecuity, is a transdermal patch used for acute migraine treatment. NuPathe's pipeline includes NP201, a long-acting treatment for Parkinson's disease, and NP202, a long-term solution for schizophrenia and bipolar disorder, both leveraging its biodegradable implant technology. The company, founded in 2005, operates as a subsidiary of Teva Pharmaceutical Industries Limited and is actively seeking partnerships to expand its global reach.

RemoteReality Corporation is a designer and manufacturer of panoramic optical systems and ultra wide-angle computational cameras. Founded in 1997 and headquartered in Windsor, Connecticut, the company specializes in delivering high-resolution, low-latency panoramic video solutions through its patented optics and advanced video processing technology. RemoteReality's products cater to various applications, including robotics, entertainment, surveillance, and video conferencing, with capabilities for both day and night use across different spectral ranges, including visible, LWIR, and MWIR. Originally established as CycloVision Technologies, Inc., the company rebranded to RemoteReality Corporation in April 2000, reflecting its focus on innovative video distribution and display technology.

NellOne Therapeutics, Inc. is a regenerative medicine company based in Oak Ridge, Tennessee, focused on developing and commercializing protein therapeutics aimed at restoring cardiac muscle mass and function in patients recovering from myocardial infarction and congestive heart failure. The company was established in 2007 as a spin-out from the U.S. Department of Energy's Oak Ridge National Laboratory, where research led by Dr. Cymbeline Culiat identified the Nell1 gene's role in the formation of essential mammalian tissues and organs. NellOne is dedicated to translating these scientific discoveries into clinical applications, specifically by leveraging Nell1 protein therapeutics to rebuild cardiac muscle and improve patient outcomes following heart-related conditions.

Bionano Genomics, Inc. is a biotechnology company focused on genome mapping and analysis. It develops and markets the Saphyr system, an advanced platform designed for ultra-sensitive and specific detection of structural variations in DNA, such as insertions, deletions, and translocations, which are often linked to genetic disorders and diseases, including cancer. The Saphyr system employs optical genome mapping technology, allowing for direct visualization and analysis of long DNA molecules without relying on sequencing. This capability provides researchers and clinicians with critical insights into the structural variations within genomes, enhancing the understanding of disease mechanisms and supporting the development of personalized treatment strategies. Bionano Genomics also offers essential reagents and data solutions, including Bionano prep kits, labeling kits, and software tools for comprehensive experiment management. Its products are primarily sold to academic and governmental research laboratories, as well as pharmaceutical, biotechnology, and contract research organizations across multiple regions, including North America, Europe, and Asia. Founded in 2003 and headquartered in San Diego, California, the company was previously known as BioNano Genomics, Inc. until its name change in July 2018.

Nistica, Inc. is a developer and manufacturer of optical networking modules focused on delivering high-bandwidth applications. Established in January 2005 and headquartered in Bridgewater, New Jersey, the company specializes in agile optical modules designed for optical system original equipment manufacturers globally. Nistica's product offerings include reconfigurable optical add/drop multiplexer (ROADM) subsystems, low port-count wavelength selective switch modules, and high port-count series products. These solutions facilitate flexible channel plans and dynamic power equalization, enabling users to customize channel spacing. Additionally, Nistica provides advanced products such as FLEXBOX, a disaggregated ROADM node aimed at software-defined networks. The company's innovative approach simplifies and automates optical network delivery, enhancing the capabilities of both edge and metro core networks. In June 2012, Nistica was acquired by Molex Optical Solutions Group, further extending its reach and impact in the optical networking industry.

Hi-G-Tek, Inc. specializes in developing and providing wireless solutions for real-time location tracking, security, and condition monitoring of high-value and sensitive cargo and assets. Founded in 1989 and based in Rockville, Maryland, the company offers a range of products, including tanker truck monitoring systems, cargo tracking solutions, and an enterprise services platform that processes data from various sensing devices. Hi-G-Tek's technology enables effective monitoring and securing of assets, whether stationary or in transit, and is particularly beneficial for industries such as fuel distribution, military logistics, and hazardous materials management. The company also produces electronic locks, seals, tags, and the necessary hardware to support its monitoring solutions. Hi-G-Tek markets its products through authorized distributors both in the United States and internationally, serving a diverse clientele that includes private enterprises and government agencies.

CDI Bioscience specializes in enhancing the yield of bioproducts through advanced genetic engineering technology. This approach allows for the precise control of cellular metabolism, facilitating a transition from a replicative state to a production mode, known as RP Shift®. The technology is primarily tailored for mammalian cells, enabling them to effectively produce proteins, peptides, and enzymes. Additionally, the design of this technology is versatile, allowing for its application in bacterial and yeast systems, thus broadening its potential for generating commercial-grade bioproducts across various platforms.

GRIDSMART Technologies develops traffic management systems for clients worldwide. Its flagship product, GRIDSMART, includes various solutions such as the Bell Camera for intersection and highway data collection, processors like the CPU/GRIDSMART processor and GS2 processor, and software modules for real-time data analysis and pedestrian tracking. The company also offers traditional zoom cameras and FLIR thermal cameras. GRIDSMART Technologies sells its products through distributors and direct sales teams in multiple countries, including the United States, Canada, Australia, Oman, and Ireland. Founded in 2006 and headquartered in Knoxville, Tennessee, the company was formerly known as Aldis, Inc. before changing its name in March 2015.

Sypherlink, Inc. is an information management software company based in Dublin, Ohio, founded in 2001. The company specializes in providing solutions that facilitate data discovery and mapping, enabling organizations to comprehend the available information and the relationships between various data sources. Its key offerings include Harvester, which automates significant portions of the data discovery process, Exploratory Warehouse for data warehouse prototyping, and Integrity, which improves ongoing data quality. Additionally, the Harvester Integrator component supports data movement capabilities, including the extraction, transformation, and loading of data into target applications. Sypherlink serves a diverse clientele, including organizations, government agencies, systems integrators, and application/tool providers.

Metatomix, established in 2000, specializes in semantic integration services. The company's solutions focus on linking data from various disparate systems to create a unified semantic understanding of information across an enterprise. This approach provides a comprehensive view of business information, enabling applications to utilize data from multiple sources rather than relying on a single system or data store. By doing so, Metatomix helps corporate enterprises and government agencies streamline workflows and enhance decision-making processes.

Superprotonic is an energy technology company established to market and commercialize the innovative solid acid fuel cell (SAFC) technology developed and patented by the company's founders at the California Institute of Technology. Solid acid fuel cells offer significant cost and performance advantages compared to other fuel cell technologies currently under development.

Endovalve is a medical device company based in Princeton, New Jersey, founded by Tracy S. Warren. The company specializes in developing percutaneous valve-replacement systems specifically designed to treat mitral regurgitation. Its innovative system allows for minimally invasive surgical procedures that facilitate complete valve replacement, significantly reducing the risks and complications associated with traditional open-heart surgery methods like sternotomy and cardiopulmonary bypass. By offering a safer and more efficient treatment option, Endovalve aims to improve patient outcomes and address mitral regurgitation before it escalates to a critical stage or leads to serious cardiac events.

RemoteReality Corporation is a designer and manufacturer of panoramic optical systems and ultra wide-angle computational cameras. Founded in 1997 and headquartered in Windsor, Connecticut, the company specializes in delivering high-resolution, low-latency panoramic video solutions through its patented optics and advanced video processing technology. RemoteReality's products cater to various applications, including robotics, entertainment, surveillance, and video conferencing, with capabilities for both day and night use across different spectral ranges, including visible, LWIR, and MWIR. Originally established as CycloVision Technologies, Inc., the company rebranded to RemoteReality Corporation in April 2000, reflecting its focus on innovative video distribution and display technology.

Hi-G-Tek, Inc. specializes in developing and providing wireless solutions for real-time location tracking, security, and condition monitoring of high-value and sensitive cargo and assets. Founded in 1989 and based in Rockville, Maryland, the company offers a range of products, including tanker truck monitoring systems, cargo tracking solutions, and an enterprise services platform that processes data from various sensing devices. Hi-G-Tek's technology enables effective monitoring and securing of assets, whether stationary or in transit, and is particularly beneficial for industries such as fuel distribution, military logistics, and hazardous materials management. The company also produces electronic locks, seals, tags, and the necessary hardware to support its monitoring solutions. Hi-G-Tek markets its products through authorized distributors both in the United States and internationally, serving a diverse clientele that includes private enterprises and government agencies.

Rajant Corporation specializes in multi-frequency wireless solutions, providing private wireless networks that leverage its innovative kinetic mesh technology. The company's offerings include BreadCrumb network nodes and InstaMesh routing software, which enable continuous and instantaneous data routing across various nodes via the most efficient traffic paths. Additionally, Rajant's CacheCrumb node features built-in processing power, allowing applications to be processed closer to the network's edge for faster access. The company serves a diverse range of sectors, including mining, oil and gas, municipalities, public safety, transportation, and utilities. Rajant's wireless systems are designed for mobility, offering portable and self-integrating networks that are secure and adaptable to varying operational needs. Founded in 2001 and headquartered in Malvern, Pennsylvania, Rajant Corporation also maintains a strategic partnership with Wabtec Corporation to enhance its service offerings.

BioVigilant Systems specializes in advanced microbial detection technology aimed at enhancing environmental monitoring across various sectors, including pharmaceuticals, biotechnology, healthcare, and environmental applications. The company's innovative instantaneous microbial detection (IMD) systems provide real-time analysis of particulate count, size, and biological status without the need for staining, reagents, or extended waiting periods. This optically-based technology streamlines the monitoring process, minimizing human intervention and improving efficiency in critical environments.

Metatomix, established in 2000, specializes in semantic integration services. The company's solutions focus on linking data from various disparate systems to create a unified semantic understanding of information across an enterprise. This approach provides a comprehensive view of business information, enabling applications to utilize data from multiple sources rather than relying on a single system or data store. By doing so, Metatomix helps corporate enterprises and government agencies streamline workflows and enhance decision-making processes.

Endovalve is a medical device company based in Princeton, New Jersey, founded by Tracy S. Warren. The company specializes in developing percutaneous valve-replacement systems specifically designed to treat mitral regurgitation. Its innovative system allows for minimally invasive surgical procedures that facilitate complete valve replacement, significantly reducing the risks and complications associated with traditional open-heart surgery methods like sternotomy and cardiopulmonary bypass. By offering a safer and more efficient treatment option, Endovalve aims to improve patient outcomes and address mitral regurgitation before it escalates to a critical stage or leads to serious cardiac events.

Multispectral Imaging, Inc. designs, develops, manufactures, and supplies infrared imaging detectors and arrays. The company provides technologies for night vision and thermal-imaging products. Its solutions include infrared imaging array detector modules that use microelectromechanical sensor and ROIC technologies to produce detectors with sensitivities; and microcantilever detector technologies, which enable detector sensitivities to the infrared detection approach. The company was founded in 2003 and is based in Parsippany, New Jersey with a branch office in Oak Ridge, Tennessee. As of April 4, 2008, Multispectral Imaging, Inc. operates as a subsidiary of Agiltron, Inc.

SmartSynch is a technology company focused on enhancing the Smart Grid through innovative solutions that enable utilities to communicate with various devices on the grid. By leveraging existing public wireless networks, such as those from major telecommunications providers, SmartSynch simplifies the deployment of smart metering systems for over 100 major electric utilities across North America. The company's smart grid technology captures and transmits real-time energy usage data, allowing for improved monitoring and control of energy consumption. This infrastructure facilitates better efficiency, helps identify and stop energy losses, and provides vital feedback for optimizing electricity generation and delivery. SmartSynch's approach not only enhances operational efficiency for utilities but also supports the integration of renewable energy sources, such as solar panels and electric vehicles, into the grid.

Sypherlink, Inc. is an information management software company based in Dublin, Ohio, founded in 2001. The company specializes in providing solutions that facilitate data discovery and mapping, enabling organizations to comprehend the available information and the relationships between various data sources. Its key offerings include Harvester, which automates significant portions of the data discovery process, Exploratory Warehouse for data warehouse prototyping, and Integrity, which improves ongoing data quality. Additionally, the Harvester Integrator component supports data movement capabilities, including the extraction, transformation, and loading of data into target applications. Sypherlink serves a diverse clientele, including organizations, government agencies, systems integrators, and application/tool providers.

Ventaira Pharmaceuticals is a specialty pharmaceutical company dedicated to developing innovative inhalation products. Utilizing its proprietary electrohydrodynamic (EHD) aerosolization technology, Ventaira focuses on creating novel inhaled drugs, such as fentanyl for managing breakthrough pain and salmeterol for treating asthma.

Safe-View, Inc. specializes in homeland security technology, focusing on the commercial application of patented Holographic Imaging technology developed by the Pacific Northwest National Laboratory. The company's flagship product, the Guardian 100, employs active millimeter wave technology to deliver clear imaging of concealed items, including metal, plastic, and ceramic materials, without the use of ionizing radiation. This innovative approach provides a safer and more effective alternative to traditional detection methods, such as metal detectors and pat-down searches, enhancing security in public spaces. Safe-View aims to improve screening systems for various applications, including passenger terminals, cargo facilities, and border security.