Battelle Ventures

Bionano Genomics, Inc. is a biotechnology company focused on genome mapping and analysis. It develops and markets the Saphyr system, an advanced platform designed for ultra-sensitive and specific detection of structural variations in DNA, such as insertions, deletions, and translocations, which are often linked to genetic disorders and diseases, including cancer. The Saphyr system employs optical genome mapping technology, allowing for direct visualization and analysis of long DNA molecules without relying on sequencing. This capability provides researchers and clinicians with critical insights into the structural variations within genomes, enhancing the understanding of disease mechanisms and supporting the development of personalized treatment strategies. Bionano Genomics also offers essential reagents and data solutions, including Bionano prep kits, labeling kits, and software tools for comprehensive experiment management. Its products are primarily sold to academic and governmental research laboratories, as well as pharmaceutical, biotechnology, and contract research organizations across multiple regions, including North America, Europe, and Asia. Founded in 2003 and headquartered in San Diego, California, the company was previously known as BioNano Genomics, Inc. until its name change in July 2018.

Bionano Genomics, Inc. is a biotechnology company focused on genome mapping and analysis. It develops and markets the Saphyr system, an advanced platform designed for ultra-sensitive and specific detection of structural variations in DNA, such as insertions, deletions, and translocations, which are often linked to genetic disorders and diseases, including cancer. The Saphyr system employs optical genome mapping technology, allowing for direct visualization and analysis of long DNA molecules without relying on sequencing. This capability provides researchers and clinicians with critical insights into the structural variations within genomes, enhancing the understanding of disease mechanisms and supporting the development of personalized treatment strategies. Bionano Genomics also offers essential reagents and data solutions, including Bionano prep kits, labeling kits, and software tools for comprehensive experiment management. Its products are primarily sold to academic and governmental research laboratories, as well as pharmaceutical, biotechnology, and contract research organizations across multiple regions, including North America, Europe, and Asia. Founded in 2003 and headquartered in San Diego, California, the company was previously known as BioNano Genomics, Inc. until its name change in July 2018.

Micro Interventional Devices, Inc., founded in 2010 and based in Newtown, Pennsylvania, is a medical device company specializing in disruptive technologies for percutaneous and minimally invasive structural heart repair procedures. The company designs and manufactures devices such as Permaseal, which facilitates transapical access and closure for catheter-based procedures, and Minimally Invasive Annuloplasty technology for tricuspid and mitral repair. Additionally, they offer Endovalve, a percutaneous mitral valve replacement system, and Permavalve, a percutaneous mitral valve with active fixation. Their proprietary technology focuses on soft-tissue anchoring and delivery devices, enabling off-pump procedures and transforming open surgical techniques into transcatheter procedures.

Proterro, Inc. is a biotechnology company based in Princeton, New Jersey, founded in 2008. It specializes in the production and marketing of sugar feedstock, specifically a fortified sucrose product known as PROTOSE. Unlike traditional methods that involve extracting sucrose from crops or breaking down cellulosic materials, Proterro utilizes patented microorganisms that synthesize sucrose directly. This innovative approach allows the company to produce a non-crop-based, fermentation-ready sugar feedstock, which mitigates the price volatility typically associated with corn and other agricultural feedstocks. By focusing on this unique production method, Proterro aims to provide a cost-effective and scalable solution for the commercial production of biofuels and biobased chemicals.

Bionano Genomics, Inc. is a biotechnology company focused on genome mapping and analysis. It develops and markets the Saphyr system, an advanced platform designed for ultra-sensitive and specific detection of structural variations in DNA, such as insertions, deletions, and translocations, which are often linked to genetic disorders and diseases, including cancer. The Saphyr system employs optical genome mapping technology, allowing for direct visualization and analysis of long DNA molecules without relying on sequencing. This capability provides researchers and clinicians with critical insights into the structural variations within genomes, enhancing the understanding of disease mechanisms and supporting the development of personalized treatment strategies. Bionano Genomics also offers essential reagents and data solutions, including Bionano prep kits, labeling kits, and software tools for comprehensive experiment management. Its products are primarily sold to academic and governmental research laboratories, as well as pharmaceutical, biotechnology, and contract research organizations across multiple regions, including North America, Europe, and Asia. Founded in 2003 and headquartered in San Diego, California, the company was previously known as BioNano Genomics, Inc. until its name change in July 2018.

Bionano Genomics, Inc. is a biotechnology company focused on genome mapping and analysis. It develops and markets the Saphyr system, an advanced platform designed for ultra-sensitive and specific detection of structural variations in DNA, such as insertions, deletions, and translocations, which are often linked to genetic disorders and diseases, including cancer. The Saphyr system employs optical genome mapping technology, allowing for direct visualization and analysis of long DNA molecules without relying on sequencing. This capability provides researchers and clinicians with critical insights into the structural variations within genomes, enhancing the understanding of disease mechanisms and supporting the development of personalized treatment strategies. Bionano Genomics also offers essential reagents and data solutions, including Bionano prep kits, labeling kits, and software tools for comprehensive experiment management. Its products are primarily sold to academic and governmental research laboratories, as well as pharmaceutical, biotechnology, and contract research organizations across multiple regions, including North America, Europe, and Asia. Founded in 2003 and headquartered in San Diego, California, the company was previously known as BioNano Genomics, Inc. until its name change in July 2018.

Nistica, Inc. specializes in the development and manufacturing of optical networking modules designed to enhance the delivery of high-bandwidth applications. The company offers a range of products, including reconfigurable optical add/drop multiplexer (ROADM) subsystems, low port-count wavelength selective switch modules, wave blocker arrays with optical programmability, and high port-count series products. Its FLEXBOX, a disaggregated ROADM node, is tailored for software-defined networks, while the company's ROADM linecards support various optical networking needs. Founded in 2005 and based in Bridgewater, New Jersey, Nistica serves optical system original equipment manufacturers (OEMs) both domestically and internationally, aiming to automate and simplify the optical network infrastructure. In 2012, Nistica was acquired by Molex Optical Solutions Group.

GRIDSMART Technologies, Inc. specializes in developing advanced traffic management systems for municipal clients both in the United States and internationally. The company offers a comprehensive suite of products under the GRIDSMART brand, which includes various camera-based solutions for traffic monitoring and data collection. Notable products include the GRIDSMART Bell Camera for intersection management, the GRIDSMART Engine for tracking and counting vehicles, motorcycles, and bicycles, and a variety of software modules that provide real-time data and alerts. GRIDSMART Technologies also offers traditional zoom and thermal imaging cameras, enhancing its traffic monitoring capabilities. The company markets its products through distributors and direct sales teams across several countries, including Canada, Australia, Oman, and Ireland. Founded in 2006 and headquartered in Knoxville, Tennessee, GRIDSMART Technologies was previously known as Aldis, Inc. and became a subsidiary of Cubic Transportation Systems in 2019.

Nistica, Inc. specializes in the development and manufacturing of optical networking modules designed to enhance the delivery of high-bandwidth applications. The company offers a range of products, including reconfigurable optical add/drop multiplexer (ROADM) subsystems, low port-count wavelength selective switch modules, wave blocker arrays with optical programmability, and high port-count series products. Its FLEXBOX, a disaggregated ROADM node, is tailored for software-defined networks, while the company's ROADM linecards support various optical networking needs. Founded in 2005 and based in Bridgewater, New Jersey, Nistica serves optical system original equipment manufacturers (OEMs) both domestically and internationally, aiming to automate and simplify the optical network infrastructure. In 2012, Nistica was acquired by Molex Optical Solutions Group.

Hepregen Corporation specializes in bio-engineering technology with a focus on developing its microliver platform, which is designed for applications in acute and chronic toxicity assessment and drug metabolism. This innovative platform supports the pharmaceutical industry in various areas, including drug discovery, disease modeling, and toxicogenomics. By collaborating with industry partners, Hepregen aims to validate its technology across a broad spectrum of applications, enhancing safety assessments and drug development processes. The potential market for the microliver platform is significant, estimated at around one billion dollars annually, reflecting its importance in improving pharmaceutical products for clinical use.

Hepregen Corporation specializes in bio-engineering technology with a focus on developing its microliver platform, which is designed for applications in acute and chronic toxicity assessment and drug metabolism. This innovative platform supports the pharmaceutical industry in various areas, including drug discovery, disease modeling, and toxicogenomics. By collaborating with industry partners, Hepregen aims to validate its technology across a broad spectrum of applications, enhancing safety assessments and drug development processes. The potential market for the microliver platform is significant, estimated at around one billion dollars annually, reflecting its importance in improving pharmaceutical products for clinical use.

NuPathe Inc., a Pennsylvania-based specialty pharmaceutical company, specializes in developing and commercializing branded therapeutics for neurological and psychiatric disorders. Its primary product, Zecuity, is a transdermal patch used for acute migraine treatment. NuPathe's pipeline includes NP201, a long-acting treatment for Parkinson's disease, and NP202, a long-term therapy for schizophrenia and bipolar disorder, both leveraging the company's biodegradable implant technology. NuPathe, now a subsidiary of Teva Pharmaceuticals, focuses on innovative neuroscience solutions and actively seeks partnerships to maximize the global potential of its product candidates.

RemoteReality Corporation specializes in the design and manufacture of ultra wide-angle computational cameras and video systems, utilizing patented optics and advanced video processing technology. Founded in 1997 and based in Windsor, Connecticut, the company creates high-resolution, real-time video solutions suitable for various applications, including robotics, entertainment, surveillance, and video conferencing. Their products are engineered to deliver low latency video across different environmental conditions and light spectra, including day and night configurations. RemoteReality was previously known as CycloVision Technologies, Inc. before rebranding in April 2000.

NellOne Therapeutics, Inc. is a regenerative medicine company based in Oak Ridge, Tennessee, focused on developing and commercializing protein therapeutics aimed at restoring cardiac muscle mass and function in patients recovering from myocardial infarctions and congestive heart failure. The company was established as a spin-off from the U.S. Department of Energy's Oak Ridge National Laboratory, where research on the Nell1 gene's pathway was conducted, revealing its role in the formation of critical mammalian tissues and organs. Founded by Battelle Ventures, NellOne is dedicated to translating this scientific discovery into effective clinical applications for heart recovery.

Bionano Genomics, Inc. is a biotechnology company focused on genome mapping and analysis. It develops and markets the Saphyr system, an advanced platform designed for ultra-sensitive and specific detection of structural variations in DNA, such as insertions, deletions, and translocations, which are often linked to genetic disorders and diseases, including cancer. The Saphyr system employs optical genome mapping technology, allowing for direct visualization and analysis of long DNA molecules without relying on sequencing. This capability provides researchers and clinicians with critical insights into the structural variations within genomes, enhancing the understanding of disease mechanisms and supporting the development of personalized treatment strategies. Bionano Genomics also offers essential reagents and data solutions, including Bionano prep kits, labeling kits, and software tools for comprehensive experiment management. Its products are primarily sold to academic and governmental research laboratories, as well as pharmaceutical, biotechnology, and contract research organizations across multiple regions, including North America, Europe, and Asia. Founded in 2003 and headquartered in San Diego, California, the company was previously known as BioNano Genomics, Inc. until its name change in July 2018.

Nistica, Inc. specializes in the development and manufacturing of optical networking modules designed to enhance the delivery of high-bandwidth applications. The company offers a range of products, including reconfigurable optical add/drop multiplexer (ROADM) subsystems, low port-count wavelength selective switch modules, wave blocker arrays with optical programmability, and high port-count series products. Its FLEXBOX, a disaggregated ROADM node, is tailored for software-defined networks, while the company's ROADM linecards support various optical networking needs. Founded in 2005 and based in Bridgewater, New Jersey, Nistica serves optical system original equipment manufacturers (OEMs) both domestically and internationally, aiming to automate and simplify the optical network infrastructure. In 2012, Nistica was acquired by Molex Optical Solutions Group.

Hi-G-Tek, Inc. specializes in the development and provision of wireless solutions for real-time location, security, and condition monitoring of high-value and sensitive cargo and assets, whether in transit or stationary. The company's offerings include a tanker truck monitoring system, cargo tracking solutions, and an enterprise services platform that analyzes and stores data from various sensing devices. Additionally, Hi-G-Tek supplies electronic sensing and locking devices, a range of locks, seals, tags, and various readers and terminals, catering to diverse markets such as fuel distribution, military logistics, and HAZMAT management. With a focus on low-power, cost-effective technology, Hi-G-Tek aims to enhance the security and monitoring of critical assets, providing its services to both private companies and government agencies. Established in 1989 and located in Rockville, Maryland, the company markets its products through authorized distributors in the United States and internationally.

CDI Bioscience specializes in enhancing the yield of bioproducts through advanced genetic engineering technology. This approach allows for the precise control of cellular metabolism, facilitating a transition from a replicative state to a production mode, known as RP Shift®. The technology is primarily tailored for mammalian cells, enabling them to effectively produce proteins, peptides, and enzymes. Additionally, the design of this technology is versatile, allowing for its application in bacterial and yeast systems, thus broadening its potential for generating commercial-grade bioproducts across various platforms.

GRIDSMART Technologies, Inc. specializes in developing advanced traffic management systems for municipal clients both in the United States and internationally. The company offers a comprehensive suite of products under the GRIDSMART brand, which includes various camera-based solutions for traffic monitoring and data collection. Notable products include the GRIDSMART Bell Camera for intersection management, the GRIDSMART Engine for tracking and counting vehicles, motorcycles, and bicycles, and a variety of software modules that provide real-time data and alerts. GRIDSMART Technologies also offers traditional zoom and thermal imaging cameras, enhancing its traffic monitoring capabilities. The company markets its products through distributors and direct sales teams across several countries, including Canada, Australia, Oman, and Ireland. Founded in 2006 and headquartered in Knoxville, Tennessee, GRIDSMART Technologies was previously known as Aldis, Inc. and became a subsidiary of Cubic Transportation Systems in 2019.

Sypherlink, Inc. is an information management software company based in Dublin, Ohio, founded in 2001. The company provides a suite of products designed to improve data handling and quality for organizations, government agencies, and systems integrators. Its flagship product, Harvester, automates the data discovery and mapping process, helping users identify available information and understand relationships between various data sources. Additionally, Sypherlink offers Exploratory Warehouse, which allows for data warehouse prototyping, and Integrity, which focuses on enhancing ongoing data quality processes. The Harvester Integrator component further supports data movement by enabling the extraction, transformation, and loading (ETL) of data into target applications.

Metatomix, founded in 2000, specializes in semantic integration services designed to address the complexities of linking data from diverse systems. The company aims to create a unified understanding of information across enterprises, enabling a comprehensive view of business data. By integrating information from multiple sources, Metatomix's solutions empower corporate enterprises and government agencies to enhance decision-making and streamline workflows. This holistic approach allows business applications to utilize data not limited to a single product or database, but instead encompasses all relevant data sources, fostering improved operational efficiency and insight.

Superprotonic is an energy technology company established to market and commercialize the innovative solid acid fuel cell (SAFC) technology developed and patented by the company's founders at the California Institute of Technology. Solid acid fuel cells offer significant cost and performance advantages compared to other fuel cell technologies currently under development.

Endovalve is a medical technology company based in Princeton, New Jersey, focused on developing percutaneous valve-replacement systems for the treatment of mitral regurgitation. Founded by Tracy S. Warren, the company’s innovative system is designed for minimally invasive surgical procedures, allowing for complete valve replacement while minimizing the risks and complications often associated with traditional surgical methods, such as sternotomy and cardiopulmonary bypass. This approach aims to provide patients with improved treatment options before their condition becomes critical or leads to serious cardiac events.

RemoteReality Corporation specializes in the design and manufacture of ultra wide-angle computational cameras and video systems, utilizing patented optics and advanced video processing technology. Founded in 1997 and based in Windsor, Connecticut, the company creates high-resolution, real-time video solutions suitable for various applications, including robotics, entertainment, surveillance, and video conferencing. Their products are engineered to deliver low latency video across different environmental conditions and light spectra, including day and night configurations. RemoteReality was previously known as CycloVision Technologies, Inc. before rebranding in April 2000.

Hi-G-Tek, Inc. specializes in the development and provision of wireless solutions for real-time location, security, and condition monitoring of high-value and sensitive cargo and assets, whether in transit or stationary. The company's offerings include a tanker truck monitoring system, cargo tracking solutions, and an enterprise services platform that analyzes and stores data from various sensing devices. Additionally, Hi-G-Tek supplies electronic sensing and locking devices, a range of locks, seals, tags, and various readers and terminals, catering to diverse markets such as fuel distribution, military logistics, and HAZMAT management. With a focus on low-power, cost-effective technology, Hi-G-Tek aims to enhance the security and monitoring of critical assets, providing its services to both private companies and government agencies. Established in 1989 and located in Rockville, Maryland, the company markets its products through authorized distributors in the United States and internationally.

Rajant Corporation specializes in multi-frequency wireless solutions, providing private wireless networks that leverage its innovative kinetic mesh technology. The company's offerings include BreadCrumb network nodes and InstaMesh routing software, which enable continuous and instantaneous data routing across various nodes via the most efficient traffic paths. Additionally, Rajant's CacheCrumb node features built-in processing power, allowing applications to be processed closer to the network's edge for faster access. The company serves a diverse range of sectors, including mining, oil and gas, municipalities, public safety, transportation, and utilities. Rajant's wireless systems are designed for mobility, offering portable and self-integrating networks that are secure and adaptable to varying operational needs. Founded in 2001 and headquartered in Malvern, Pennsylvania, Rajant Corporation also maintains a strategic partnership with Wabtec Corporation to enhance its service offerings.

BioVigilant Systems specializes in advanced microbial detection technology aimed at enhancing environmental monitoring across various sectors, including pharmaceuticals, biotechnology, healthcare, and environmental applications. The company's innovative instantaneous microbial detection (IMD) systems provide real-time analysis of particulate count, size, and biological status without the need for staining, reagents, or extended waiting periods. This optically-based technology streamlines the monitoring process, minimizing human intervention and improving efficiency in critical environments.

Metatomix, founded in 2000, specializes in semantic integration services designed to address the complexities of linking data from diverse systems. The company aims to create a unified understanding of information across enterprises, enabling a comprehensive view of business data. By integrating information from multiple sources, Metatomix's solutions empower corporate enterprises and government agencies to enhance decision-making and streamline workflows. This holistic approach allows business applications to utilize data not limited to a single product or database, but instead encompasses all relevant data sources, fostering improved operational efficiency and insight.

Endovalve is a medical technology company based in Princeton, New Jersey, focused on developing percutaneous valve-replacement systems for the treatment of mitral regurgitation. Founded by Tracy S. Warren, the company’s innovative system is designed for minimally invasive surgical procedures, allowing for complete valve replacement while minimizing the risks and complications often associated with traditional surgical methods, such as sternotomy and cardiopulmonary bypass. This approach aims to provide patients with improved treatment options before their condition becomes critical or leads to serious cardiac events.

Multispectral Imaging, Inc. designs, develops, manufactures, and supplies infrared imaging detectors and arrays. The company provides technologies for night vision and thermal-imaging products. Its solutions include infrared imaging array detector modules that use microelectromechanical sensor and ROIC technologies to produce detectors with sensitivities; and microcantilever detector technologies, which enable detector sensitivities to the infrared detection approach. The company was founded in 2003 and is based in Parsippany, New Jersey with a branch office in Oak Ridge, Tennessee. As of April 4, 2008, Multispectral Imaging, Inc. operates as a subsidiary of Agiltron, Inc.

SmartSynch is a technology company specializing in smart grid solutions that enable utilities to communicate with devices on the grid through public wireless networks. By utilizing existing cellular infrastructure, SmartSynch simplifies the deployment of smart metering technology for over 100 North American electric utilities. Their innovations facilitate the two-way delivery of real-time energy usage data, allowing for improved monitoring, control, and efficiency in energy distribution. SmartSynch's solutions help identify and mitigate energy losses, optimize power factors, and provide essential feedback for managing energy loads during peak demand. With the potential benefits of smart grid technologies projected to reach significant financial savings over the next two decades, SmartSynch aims to create substantial value for its clients by enhancing the capabilities of the electricity grid through its advanced infrastructure solutions.

Sypherlink, Inc. is an information management software company based in Dublin, Ohio, founded in 2001. The company provides a suite of products designed to improve data handling and quality for organizations, government agencies, and systems integrators. Its flagship product, Harvester, automates the data discovery and mapping process, helping users identify available information and understand relationships between various data sources. Additionally, Sypherlink offers Exploratory Warehouse, which allows for data warehouse prototyping, and Integrity, which focuses on enhancing ongoing data quality processes. The Harvester Integrator component further supports data movement by enabling the extraction, transformation, and loading (ETL) of data into target applications.

Ventaira Pharmaceuticals is an emerging specialty pharmaceutical company dedicated to the development of innovative inhalation products. The company employs its proprietary electrohydrodynamic aerosolization and formulation technologies to create new inhaled drugs. Among its key products are fentanyl, aimed at treating breakthrough pain, and salmeterol, used for asthma management. Ventaira Pharmaceuticals focuses on advancing its unique technologies to enhance drug delivery and improve treatment options for patients.

SafeView, Inc. is a provider of homeland security technology services, specializing in advanced security screening systems. The company focuses on commercializing patented holographic imaging technology developed by the Pacific Northwest National Laboratory. Its flagship product, the Guardian 100, utilizes active millimeter wave technology to safely and clearly detect hidden items, including metal, plastic, and ceramic, without the use of ionizing radiation. This innovative approach offers a significant improvement over traditional methods such as metal detectors and pat-down searches, enhancing safety in public spaces. SafeView aims to address security needs in various environments, including passenger terminals, cargo facilities, and border security applications.