PolyCore Therapeutics
Seed Round in 2022
PolyCore Therapeutics is focused on developing innovative treatments for central nervous system (CNS) disorders, specifically targeting dyskinesia and cognitive impairment. The company aims to create new, affordable therapies that address the side effects associated with the treatment of Parkinson's disease and other neurological conditions. By enhancing patient mobility and quality of life, PolyCore Therapeutics seeks to contribute to more effective management of these disorders while also aiming to reduce overall healthcare costs. Their experienced team of scientists and life sciences professionals is dedicated to advancing research in this critical area of healthcare.
AmorSui
Seed Round in 2022
AmorSui is a modern protective apparel company that specializes in the design and innovation of medical gowns and lab jackets for healthcare professionals. Founded in 2020 by Beau Wangtrakuldee, PhD, the company emerged from a personal experience that highlighted the need for better protective gear. AmorSui's products are characterized by their antimicrobial and static-resistant properties, offering protection against bodily fluids while being reusable and recyclable. The company focuses on delivering high-quality, comfortable, and eco-friendly personal protective equipment that is entirely made and sourced in the USA. Additionally, AmorSui provides a platform for managing and procuring reusable kits, utilizing data analytics to monitor product life cycles, thereby helping hospitals and companies reduce costs and minimize waste while ensuring employee safety.
Astarte Medical
Series A in 2021
Astarte Medical, established in 2016 and headquartered in Yardley, Pennsylvania, specializes in developing software for clinical intelligence. Its platform offers a real-time, comprehensive view of clinical data, focusing on the gut health of preterm infants in Neonatal Intensive Care Units (NICUs). By standardizing and streamlining feeding practices, Astarte Medical empowers clinical care teams to make more informed decisions, ultimately enhancing patient outcomes and optimizing care for vulnerable pediatric populations.
RecoveryLink
Pre Seed Round in 2021
RecoveryLink is a developer of a digital recovery support platform aimed at improving behavioral health outcomes. The platform provides a comprehensive suite of services, including electronic recovery records, asynchronous digital training, individual telerecovery peer services, and live video group-based recovery support. By offering these tools, RecoveryLink seeks to enhance accessibility and effectiveness in recovery support, ultimately transforming systems within the behavioral health sector.
Vesteck is a clinical stage medical device company dedicated to advancing proprietary technology in the aortic repair, structural heart, and gastrointestinal markets. The company's flagship product, the Suture-Tightâ„¢ nitinol suture delivery catheter, offers an innovative solution for endovascular aortic repair by securely suturing grafts to the aorta during initial implantation. This technology addresses critical challenges such as graft migration and leaks, which can lead to complex and costly repairs. By improving the efficacy of aortic repairs and providing significant benefits to healthcare providers, payors, and patients, Vesteck aims to enhance patient outcomes in the treatment of aortic aneurysms and related conditions.
Pression
Pre Seed Round in 2020
Pression is a developer of a patented, non-invasive smart compression platform known as the Wave, which aims to enhance circulation throughout the body and improve cardiac function. The primary focus of the company is to assist heart failure patients, addressing the issue of excess fluid retention, a leading cause of hospitalizations in the United States. By increasing oxygen delivery to vital organs, the Wave system seeks to enhance exercise tolerance and overall quality of life for individuals with circulatory conditions. The technology is built on established scientific principles and offers improvements over previous systems, emphasizing patient independence and health.
OsciFlex
Debt Financing in 2020
OsciFlex LLC, founded in 2017 and based in Philadelphia, Pennsylvania, specializes in developing a wearable medical device aimed at preventing blood clots in patients. The device functions by stimulating calf muscle contractions through a muscle stretch reflex, which promotes valve sinus recirculatory flow. This innovative approach helps to prevent venous thromboembolism (VTE), a serious condition that can lead to significant health complications. By offering an alternative to traditional anti-coagulation pharmaceuticals, which can be costly and carry risks, OsciFlex aims to enhance patient care and reduce healthcare costs associated with blood clot management.
Chromatan
Debt Financing in 2020
ChromaTan Inc. specializes in developing continuous countercurrent tangential chromatography (CCTC) technology for the purification of monoclonal antibodies and proteins. The company's innovative platform addresses significant process bottlenecks in therapeutic protein production, offering a cost-effective, column-free, and continuous purification solution. This technology has undergone extensive beta testing with numerous leading biotech firms, demonstrating a 5-15 times increase in throughput while maintaining or improving product quality. Founded in 2007 and headquartered in Lower Gwynedd, Pennsylvania, ChromaTan aims to provide scalable and efficient alternatives to traditional large-scale column chromatography processes, thereby lowering production costs for biotechnology and contract manufacturing companies.
Mediscore
Debt Financing in 2020
Mediscore Health is a physician-led company that specializes in providing data insights and technology-driven solutions for chronic care management and risk adjustment, primarily targeting Medicare Advantage payers and Accountable Care Organizations (ACOs). Founded in 2017 and headquartered in Philadelphia, with an additional location in Santa Monica, Mediscore offers a range of services, including physician-driven chart reviews, analytics, predictive diagnostics, and point-of-care disease management. The company's solutions are designed to assist healthcare providers in diagnosing, documenting, and managing patients with chronic illnesses at the primary care level, thereby enhancing patient care and optimizing healthcare outcomes.
Repisodic
Debt Financing in 2020
Repisodic, Inc. is a healthcare technology company based in Philadelphia, Pennsylvania, focused on improving the transition of patients from hospitals to post-acute care settings, such as nursing homes and rehabilitation centers. Founded in 2017, Repisodic offers solutions that enhance care decision-making for patients, families, and caregivers. Its flagship products include Repisodic Choice, which helps hospitals and health systems create dynamic preferred provider networks tailored to individual patient needs, and Repisodic Link, designed for post-acute care providers to facilitate referrals and connect with patients. The platform utilizes proprietary data and automation to streamline the discharge process, allowing discharge planners to match patients with suitable post-discharge options based on factors like insurance networks and clinical capabilities. Overall, Repisodic aims to revolutionize how care decisions are made, ensuring that patients receive optimal post-hospital care.
iOrtho+
Debt Financing in 2020
iOrtho+ is a medical software company that specializes in orthopedic care through its innovative web-based application, the Mobil-Aider. This premium orthopedic app is designed to quantify joint mobility, enabling clinicians to assess a wide range of motions across multiple joints. The Mobil-Aider includes 450 tests and 1,300 references, along with 100 mobilization techniques, offering a comprehensive resource for orthopedic professionals. The application features concise descriptions, images, videos, and statistical data, as well as direct links to relevant literature, all aimed at enhancing the quality of treatments and improving clinical outcomes.
Excision BioTherapeutics
Debt Financing in 2020
Excision BioTherapeutics Inc. is a life science company based in Philadelphia, Pennsylvania, established in 2015. The company specializes in developing gene editing therapeutics aimed at treating life-threatening diseases caused by neurotropic viruses. Utilizing CRISPR-based technology, Excision BioTherapeutics focuses on creating advanced gene-editing medicines that can eradicate or disrupt viral genes in human patients. The company is committed to advancing these therapeutics to ensure they are safe and effective, with the goal of significantly improving the lives of individuals affected by viral infections worldwide.
Bainbridge Health
Debt Financing in 2020
Bainbridge Health, Inc. is a Philadelphia-based company that develops a clinical intelligence and data analytics platform focused on improving medication safety in hospital systems. Founded in 2016, the company provides solutions specifically for medication safety leaders, including an infusion pump management software known as InfusionWare. This platform allows clinicians to manage infusion data centrally, enhancing patient safety by streamlining data handling and reducing the likelihood of medication errors. Bainbridge Health’s vendor-agnostic approach eliminates the need for cumbersome data management practices, enabling hospitals to mitigate risks associated with medication errors while also lowering avoidable costs.
Cassian Solutions
Seed Round in 2020
Cassian Solutions, Inc. is a company that develops innovative medication management solutions, including a phone case medication dispenser and a comprehensive application designed to enhance patient compliance. Founded in 2018 and based in Phoenixville, Pennsylvania, the company targets pharmacies, clinical trial organizations, drug manufacturers, and insurers. Its platform addresses critical issues in patient monitoring and data reporting within the specialty medication market, clinical trials, and healthcare systems, aiming to improve health outcomes and reduce healthcare costs. By leveraging the widespread use of smartphones, Cassian Solutions focuses on creating personalized patient journeys that enhance engagement and facilitate real-time communication among all stakeholders involved in medication management.
SFA Therapeutics
Grant in 2020
SFA Therapeutics, Inc. is a development-stage bio-pharmaceutical company located in Jenkintown, Pennsylvania. The company specializes in creating drugs derived from microbiome-derived metabolites aimed at treating chronic inflammatory diseases and cancer. By harnessing compounds discovered in the human microbiome, SFA Therapeutics seeks to provide innovative therapeutic solutions for various medical conditions, including autoimmune diseases and liver disorders.
Open Medical Innovation
Grant in 2020
Open Medical Innovation is an organization founded by leaders from Archimedic, NextFab, and the University of Pennsylvania. We launched this organization with a focus on addressing the shortage of Personal Protective Equipment (PPE) during the COVID-19 outbreak. We intend to use this website to share information, collect feedback, and fulfill the unmet needs of patients and providers.
Narbis specializes in wearable technology aimed at enhancing mental wellness through neurofeedback. The company's flagship product, Narbis Smartglasses, is designed to assist users, particularly those with ADHD, in improving focus and concentration without the use of medication. These glasses employ a patented conditioning mechanism developed in collaboration with NASA, allowing users to train their brains while engaging in everyday activities like homework or reading. Additionally, Narbis offers a product called illume, which combines colored light, sound, and tactile transducers to facilitate Audio Visual Entrainment (AVE). This technology promotes relaxation, reduces anxiety, enhances focus, and supports meditation practices. Both products are available for purchase directly from the company's website.
DRSLINQ is developing a mobile EKG device that is coupled to an interactive application powered by a natural language processing integrated with a machine learning platform to appropriately triage chest pain patients to the ER.
Optical Inventory Solutions
Grant in 2020
Optical Inventory Solutions specializes in the development of ViewVax, an innovative automated vaccine inventory management system. ViewVax is designed to seamlessly integrate with existing medical refrigerators in hospitals, clinics, and doctors' offices, allowing these facilities to better organize and manage their vaccine supplies. The system employs a web-connected camera that accurately counts on-hand vaccine inventory, facilitating automatic reordering and reducing excess stock levels. With its robust design capable of withstanding cold refrigeration environments, ViewVax enhances operational efficiency by streamlining the recognition of vaccines and ensuring accurate data collection, ultimately supporting medical institutions in maintaining optimal inventory management for vaccines.
AAPlasma is developing a cold plasma-based system that is based on previously-successful technology capable of achieving in-between-patient decontamination of PPE items to allow for rapid reuse.
Cogwear is a brain technology company focused on addressing the needs of individuals suffering from anxiety and depression. The firm is developing a next-generation wearable device that enhances traditional physical measurements by integrating cognitive and emotional insights. This innovation aims to transition brain monitoring from laboratory settings to everyday life, providing users with real-time access to clinical-grade cognitive and emotional data. Utilizing AI-powered algorithms and proprietary dry electroencephalography (EEG) sensors, the wearable comfortably and accurately measures brain activity. The device captures and analyzes brainwaves, enabling users to receive feedback on their mental state through a secure app and shareable dashboard. By unlocking valuable insights into brain health, Cogwear aspires to improve individual well-being and performance.
Pression is a developer of a patented, non-invasive smart compression platform known as the Wave, which aims to enhance circulation throughout the body and improve cardiac function. The primary focus of the company is to assist heart failure patients, addressing the issue of excess fluid retention, a leading cause of hospitalizations in the United States. By increasing oxygen delivery to vital organs, the Wave system seeks to enhance exercise tolerance and overall quality of life for individuals with circulatory conditions. The technology is built on established scientific principles and offers improvements over previous systems, emphasizing patient independence and health.
Narbis specializes in wearable technology aimed at enhancing mental wellness through neurofeedback. The company's flagship product, Narbis Smartglasses, is designed to assist users, particularly those with ADHD, in improving focus and concentration without the use of medication. These glasses employ a patented conditioning mechanism developed in collaboration with NASA, allowing users to train their brains while engaging in everyday activities like homework or reading. Additionally, Narbis offers a product called illume, which combines colored light, sound, and tactile transducers to facilitate Audio Visual Entrainment (AVE). This technology promotes relaxation, reduces anxiety, enhances focus, and supports meditation practices. Both products are available for purchase directly from the company's website.
Hava Health
Pre Seed Round in 2019
Hava Health, Inc. is a biotechnology company based in the United States that specializes in developing innovative solutions for nicotine addiction. The company manufactures a smoking cessation device that includes a connected vape pen designed to assist individuals in their efforts to quit smoking. This device pairs with a smartphone application called Hale, which serves as a digital support tool for users undergoing nicotine de-addiction. Through its focus on combining technology with therapeutic approaches, Hava Health aims to provide effective support for those seeking to overcome nicotine dependence.
Navrogen
Convertible Note in 2019
Navrogen, Inc. is a biopharmaceutical company based in Philadelphia, Pennsylvania, founded in 2017. The company specializes in the targeted treatment of cancer by enhancing the immune system's ability to combat tumors. Navrogen develops technology that identifies proteins produced by tumors that suppress the body's humoral immune response, which can hinder both natural immunity and the effectiveness of antibody-based therapies. By assembling a comprehensive database of tumor types that produce these immunosuppressive factors, Navrogen aims to support physicians in overcoming these challenges, thereby improving cancer treatment outcomes.
Astarte Medical
Series A in 2019
Astarte Medical, established in 2016 and headquartered in Yardley, Pennsylvania, specializes in developing software for clinical intelligence. Its platform offers a real-time, comprehensive view of clinical data, focusing on the gut health of preterm infants in Neonatal Intensive Care Units (NICUs). By standardizing and streamlining feeding practices, Astarte Medical empowers clinical care teams to make more informed decisions, ultimately enhancing patient outcomes and optimizing care for vulnerable pediatric populations.
RoundTrip
Series A in 2019
RoundTrip, Inc. operates a digital marketplace that facilitates non-emergency medical transportation by connecting patients with a network of ride providers. Founded in 2014 and based in Philadelphia, Pennsylvania, the company offers a user-friendly software platform that allows healthcare organizations and transportation companies to schedule, dispatch, and monitor patient rides. RoundTrip serves hospitals and health plans in ten states, aiming to improve care coordination and reduce patient no-shows. The platform provides access to various transportation options, including medical cars, wheelchair vans, and stretcher vehicles. RoundTrip has established strategic partnerships with notable healthcare organizations, enhancing its service offerings. The team behind RoundTrip consists of professionals with experience as paramedics and in healthcare management, which informs their approach to addressing the challenges in medical transportation.
Tridiuum, Inc. is a Philadelphia-based digital health company established in 1997 that specializes in software-as-a-service solutions for behavioral health providers, patients, and health systems. The core offering, Tridiuum1, is a cloud-based platform designed to enhance behavioral health outcomes management by monitoring patient symptoms and treatment progress. It integrates digital health assessments with an analytics engine to identify behavioral health issues, assign risk scores, and provide real-time alerts at the point of care. Additionally, the platform supports video-based virtual visits and other features, enabling clinicians to effectively evaluate and manage patients with various conditions. The company is backed by a team of experts in behavioral medicine and digital health technologies, with a strong foundation in clinical research and a history of contributions to peer-reviewed scientific literature.
Bakround
Seed Round in 2018
Bakround, Inc. is a healthcare recruiting and AI platform based in Philadelphia, Pennsylvania, founded in 2014. The company offers a suite of online services aimed at enhancing the recruitment process, including job listings, resume matching, and employment verification. Bakround's platform utilizes artificial intelligence to improve the precision of candidate searches, enabling recruiters to effectively match applicants' qualifications with specific job requirements. Additionally, it provides tools for employees and job seekers to store and share their employment information, facilitating a more streamlined recruitment experience.
MBF Therapeutics
Seed Round in 2018
MBF Therapeutics, Inc. is a veterinary oncology company that specializes in developing and commercializing innovative therapies for cancer treatment in dogs and cats. The company's product portfolio features targeted immunotherapies and small molecule drugs designed to disrupt tumor cell metabolism while sparing healthy tissues. Key products include MBFT-101, a combination therapy for sarcomas and lymphoma that utilizes a proprietary polyamine transport inhibitor alongside a potent inhibitor of ornithine decarboxylase, and MBFT-102, an immunotherapy based on the tumor suppressor/cytokine mda-7/IL24, which has shown promise in human clinical trials for various advanced cancers. Additionally, MBF Therapeutics is advancing a gene-based vaccine platform aimed at improving treatments for both cancer and infectious diseases in animals, with the potential to transform veterinary medicine. The company is located in Ambler, Pennsylvania, and maintains a strategic partnership with the Lankenau Institute for Medical Research.
RoundTrip
Seed Round in 2018
RoundTrip, Inc. operates a digital marketplace that facilitates non-emergency medical transportation by connecting patients with a network of ride providers. Founded in 2014 and based in Philadelphia, Pennsylvania, the company offers a user-friendly software platform that allows healthcare organizations and transportation companies to schedule, dispatch, and monitor patient rides. RoundTrip serves hospitals and health plans in ten states, aiming to improve care coordination and reduce patient no-shows. The platform provides access to various transportation options, including medical cars, wheelchair vans, and stretcher vehicles. RoundTrip has established strategic partnerships with notable healthcare organizations, enhancing its service offerings. The team behind RoundTrip consists of professionals with experience as paramedics and in healthcare management, which informs their approach to addressing the challenges in medical transportation.
VitalTrax
Seed Round in 2017
VitalTrax connects patients with clinical trials with its cloud-based clinical trial network. VitalTrax offers Wing, a solution that simplifies clinical trials enrollment. Wing is a clinical trial network that provides innovative ways for people to easily seek optional treatments for themselves or people that they love and play an important role in helping develop new ways to fight diseases.
Keriton
Seed Round in 2017
Keriton LLC is a provider of a pumped breast milk management system specifically designed for neonatal intensive care units (NICUs). Based in Philadelphia, Pennsylvania, the company offers a comprehensive platform that enhances patient safety and streamlines nursing workflows. This system enables healthcare professionals to track milk-bottle inventory, manage feeding orders, and handle first-in-first-out (FIFO) bottle flow, including notifications for expiry dates and misfeed alerts. The platform also facilitates real-time insights into lactating mothers' milk production patterns and includes a media-sharing feature for nurses to communicate with mothers by sharing photos and videos of their babies. With a track record of managing over 1.5 million feeds and preventing nearly 30,000 errors, Keriton's solution aims to improve health outcomes and reduce the cognitive burden on hospital staff. Since its incorporation in 2016, Keriton has been deployed in numerous larger enterprise health systems, demonstrating its effectiveness in enhancing the care provided to infants in NICUs.
Binto LLC, established in 2015 and based in Philadelphia, Pennsylvania, specializes in creating health supplements aimed at supporting women's reproductive health. The company offers a range of products, including fertility and women's health supplements, as well as organic period products such as tampons. Binto designs supplement kits tailored for women of all ages, utilizing natural and effective ingredients that are gluten-free, vegan-friendly, and free from preservatives and fillers. Each supplement is formulated with methylated folate, focusing on preventative care to enhance women's health from menstruation to menopause. Binto also provides access to licensed healthcare professionals, ensuring that women receive safe and effective over-the-counter products at affordable prices.
Shock Analytics
Seed Round in 2016
Shock Analytics LLC is an early-stage biomedical device company based in Philadelphia, Pennsylvania, founded in 2016. The firm specializes in designing and manufacturing noninvasive devices that estimate Systemic Vascular Resistance (SVR), a critical indicator for conditions such as congestive heart failure and sepsis. By utilizing hemodynamic information, Shock Analytics aims to provide medical professionals with innovative tools to improve the treatment and management of critically and chronically ill patients. Through its focus on smarter technologies, the company seeks to transform the landscape of biomedical diagnostics and enhance patient care.
SonoSolve
Seed Round in 2016
SonoSolve is a revolutionary new device that aims to eliminate catheter-associated complications, using non-invasive sound waves to clear obstructions and biofilms within catheters. SonoSolve is the BUZZ in Blockages!
Instadiagnostics
Seed Round in 2016
Instadiagnostics Inc. develops a point-of-care (POC) diagnostic platform that aims to bring centralized laboratory testing directly to patients at their bedside. This innovative platform enables early diagnosis and treatment monitoring in various settings, including primary care centers, community clinics, and emergency departments. By eliminating the need for additional trips for blood tests and reducing lengthy wait times for results, Instadiagnostics enhances patient care and satisfaction. The company, incorporated in 2015 and based in Philadelphia, Pennsylvania, focuses on streamlining the diagnostic process, ultimately aiming to reduce the number of medical visits and overall healthcare costs.
GSI Health
Seed Round in 2016
GSI Health, LLC is a health information technology company that specializes in population health management through its cloud-based software solutions. Founded in 2003 and headquartered in Philadelphia, Pennsylvania, with an additional office in New York, the company provides tools for care coordination, care management, and health insights. GSI Health's platform is designed to enhance communication and information sharing among healthcare providers, including hospitals, health systems, managed care organizations, Medicaid programs, and community-based organizations. The solutions aim to improve transitions in care, reduce avoidable hospital readmissions, and support analytics and reporting for patient care. Additionally, the platform includes built-in Health Information Exchange (HIE) capabilities, facilitating seamless data sharing across organizational boundaries. As of October 2019, GSI Health operates as a subsidiary of Medecision, Inc.
Polaris Health Directions
Seed Round in 2016
POLARIS HEALTH DIRECTIONS develops and markets behavioral health outcomes assessment and management systems to help deliver better health outcomes at a reduced cost. Polaris systems are designed for use by health care providers, managed care organizations, government agencies and pharmaceutical companies, and focus on addressing the impact mental health conditions have on physical health and an individual’s welfare. These solutions help Polaris's clients identify, monitor and address psychosocial and behavioral health conditions to curb long-term health effects and costs.
CyberCrunch
Seed Round in 2016
CyberCrunch specializes in data destruction and e-waste disposal solutions, offering comprehensive recycling services for a wide range of electronic equipment, including computers, monitors, networking devices, and batteries. The company provides secure destruction services such as on-site and off-site shredding, magnetic degaussing, and low-level wiping, ensuring permanent data destruction. Additionally, CyberCrunch offers IT consulting services for businesses undergoing workstation replacements, office relocations, and asset management. The company serves various sectors, including healthcare, financial services, education, and small businesses. Founded in 2010 in Greensburg, Pennsylvania, CyberCrunch was formerly known as Commonwealth Computer Recycling, LLC before rebranding in February 2017.
Cagent Vascular
Seed Round in 2016
Cagent Vascular, LLC is a medical device company based in Wayne, Pennsylvania, focused on developing innovative solutions for cardiovascular diseases. The company specializes in angioplasty balloons that utilize proprietary serration technology to enhance treatment outcomes. Its flagship product, the Serranator, features serrated metal strips embedded in a semi-compliant balloon, designed specifically for the treatment of atherosclerosis and conditions such as peripheral artery disease and chronic limb-threatening ischemia. By employing a minimally invasive approach, Cagent Vascular aims to improve vessel dilatation during cardiovascular interventions, ultimately enhancing patient care and quality of life. Founded in 2014, the company is dedicated to advancing intravascular technology in the medical field.
PolyCore Therapeutics
Seed Round in 2016
PolyCore Therapeutics is focused on developing innovative treatments for central nervous system (CNS) disorders, specifically targeting dyskinesia and cognitive impairment. The company aims to create new, affordable therapies that address the side effects associated with the treatment of Parkinson's disease and other neurological conditions. By enhancing patient mobility and quality of life, PolyCore Therapeutics seeks to contribute to more effective management of these disorders while also aiming to reduce overall healthcare costs. Their experienced team of scientists and life sciences professionals is dedicated to advancing research in this critical area of healthcare.
Ultraflex Systems
Seed Round in 2016
Ultraflex Systems specializes in designing and engineering custom Range of Motion (ROM) braces that enhance movement and promote active living. With over 25 years of experience, the company collaborates closely with physicians, physical therapists, and specialists to deliver innovative orthopedic and neurological solutions. Ultraflex Systems distinguishes itself through a dedicated direct care team, which includes sales professionals and certified orthotists or fitters. This team oversees the entire process from the physician's referral to brace delivery and subsequent patient follow-up. The company’s custom-molded braces are crafted in its fabrication facilities to ensure optimal fit and effectiveness, ultimately improving joint and limb motion and supporting the musculoskeletal system for better patient outcomes.
Mitochon Pharmaceuticals
Venture Round in 2016
Mitochon Pharmaceuticals, Inc. is a biotechnology company established in 2014 and based in Blue Bell, Pennsylvania. The company is dedicated to developing drugs that target mitochondrial function, aiming to address significant unmet medical needs in treating serious diseases. Its primary focus is on neurodegenerative and neuromuscular disorders, including Huntington's disease, Alzheimer's disease, Parkinson's disease, Duchenne muscular dystrophy, and epilepsy, among others. Mitochon is also exploring potential therapies for metabolic disorders related to over-nutrition, such as diabetes and obesity. The company's research is grounded in the understanding that various diseases are linked to mitochondrial dysfunction, and by correcting these malfunctions, Mitochon seeks to pave the way for innovative disease-modifying therapies. The leadership team comprises experienced industry professionals with a strong commitment to advancing breakthrough drug therapies for conditions with limited treatment options.
Arcadian Telepsychiatry Services
Seed Round in 2016
Arcadian Telepsychiatry, LLC is a provider of psychiatric services that connects mental health professionals with patients in both remote and urban locations. The company offers a comprehensive range of services, including on-demand emergency consultations for emergency departments and crisis centers, inpatient consultations, initial psychiatric evaluations, medication management, and scheduled clinics for children, adolescents, and adults. Additionally, Arcadian conducts pre-admission psychiatric assessments, staffing conferences with hospital personnel, and provides training and education on psychiatric emergency services and telepsychiatry. The organization also facilitates a network for video conferencing and Internet access among hospitals, clinics, and public health departments, and delivers behavioral health solutions for skilled nursing and assisted living facilities. Founded in 2012 and headquartered in Fort Washington, Pennsylvania, Arcadian Telepsychiatry aims to enhance access to mental health care while improving collaboration between providers, families, and patients.
Essential Medical
Seed Round in 2016
Essential Medical is a family owned & operated business that was started in 1985. We are a broad based supplier of home medical and health related products designed with the needs of the user in mind. Within this online website you will find many different product options to meet a variety of life styles and physical conditions. If you are a home medical equipment dealer and would like to be set up to order Essential products, please click on the Prospective Dealers tab. If you would like to purchase products for yourself, family member or friend, our fine products are available through your local medical equipment dealer or pharmacy. Please consult the yellow pages of your local telephone book under Hospital and Medical Equipment.
Instadiagnostics
Seed Round in 2016
Instadiagnostics Inc. develops a point-of-care (POC) diagnostic platform that aims to bring centralized laboratory testing directly to patients at their bedside. This innovative platform enables early diagnosis and treatment monitoring in various settings, including primary care centers, community clinics, and emergency departments. By eliminating the need for additional trips for blood tests and reducing lengthy wait times for results, Instadiagnostics enhances patient care and satisfaction. The company, incorporated in 2015 and based in Philadelphia, Pennsylvania, focuses on streamlining the diagnostic process, ultimately aiming to reduce the number of medical visits and overall healthcare costs.
Life.io
Seed Round in 2016
Life.io is the world’s first web-based platform specifically designed to help people make better decisions every moment, to take care of themselves more, to engage more, to simply live more. Delivered through insurance companies or employers, it’s always on, sharing inspired ideas on how to live better today and every day after.
Kynectiv, Inc. specializes in simulation-based products and technology platforms that cater to global audiences, particularly in the healthcare sector. The company offers a learning platform that enables organizations to design assessment, education, and training programs, enhancing decision-making through real-world engagement. Notable products include CommSim, which facilitates remote interactions between role-playing coaches and learners, and Synapse DX, a comprehensive solution aimed at helping healthcare organizations understand and influence audience decision-making experiences. Founded in 2010 and headquartered in Chadds Ford, Pennsylvania, Kynectiv was previously known as DecisionSim, Inc. and has operated as a subsidiary of US HealthConnect since 2019.
Life.io
Seed Round in 2015
Life.io is the world’s first web-based platform specifically designed to help people make better decisions every moment, to take care of themselves more, to engage more, to simply live more. Delivered through insurance companies or employers, it’s always on, sharing inspired ideas on how to live better today and every day after.
ZSX Medical
Venture Round in 2015
ZSX Medical, LLC is a medical device development company based in Philadelphia, Pennsylvania, established in 2009. It specializes in creating bio-absorbable products for internal closure in minimally invasive surgeries. The company is focused on its flagship product, Zip-stitch, a surgical closure system designed to facilitate challenging surgical closures quickly and effectively. This device aims to enhance surgical efficiency by reducing operative time and minimizing complications such as infection, tissue adhesion, and dehiscence, compared to traditional sutures or staples. By improving surgical outcomes and reducing healthcare costs, ZSX Medical seeks to benefit both hospitals and patients.
Grand Round Table
Seed Round in 2015
Grand Round Table Inc. is a developer of clinical decision support tools aimed at enhancing diagnostic accuracy for healthcare providers. The company's flagship system, Grand Round Table, integrates with electronic health records to assist doctors in diagnosing patients by comparing their cases against a comprehensive database of deidentified health records, case reports, and evidence-based medical literature, including resources from the University of Pennsylvania. This technology enables physicians to access insights from previous cases, facilitating quicker and more informed treatment decisions for complex patients. By streamlining the decision-making process, Grand Round Table helps hospitals and clinics reduce unnecessary tests, ineffective treatments, and consultations, ultimately saving time and costs in patient care. Established in 2011, the company is headquartered in Philadelphia, Pennsylvania.
DecNut specializes in developing point-of-care technologies aimed at enhancing clinical decision-making across various healthcare settings. The company's tools integrate evidence-based clinical practice guidelines into the workflow of healthcare providers, facilitating improved resource utilization and patient care outcomes. By offering an application that allows professionals to easily aggregate, update, disseminate, and evaluate tailored clinical decision support, DecNut supports healthcare practitioners in making informed decisions, ultimately leading to more efficient and effective healthcare delivery.
Yorn LLC is a real-time feedback and engagement platform based in Philadelphia, Pennsylvania, primarily serving the healthcare sector. Founded in 2008, the platform empowers patients and consumers to provide immediate feedback on their experiences through various digital devices, such as smartphones, tablets, and laptops. This feedback allows healthcare providers and payers to identify issues and implement necessary operational changes to enhance patient experience, satisfaction, and compliance with care plans. In addition to healthcare, Yorn also caters to the hospitality, business, enterprise, meetings and events, and automotive sectors, helping organizations understand and improve customer experiences through actionable insights derived from authentic consumer feedback.
Kynectiv
Seed Round in 2015
Kynectiv, Inc. specializes in simulation-based products and technology platforms that cater to global audiences, particularly in the healthcare sector. The company offers a learning platform that enables organizations to design assessment, education, and training programs, enhancing decision-making through real-world engagement. Notable products include CommSim, which facilitates remote interactions between role-playing coaches and learners, and Synapse DX, a comprehensive solution aimed at helping healthcare organizations understand and influence audience decision-making experiences. Founded in 2010 and headquartered in Chadds Ford, Pennsylvania, Kynectiv was previously known as DecisionSim, Inc. and has operated as a subsidiary of US HealthConnect since 2019.
Prescribe Well
Seed Round in 2015
PrescribeWell, Inc. is a Hatfield, Pennsylvania-based company that offers a platform-as-a-service designed to assist healthcare providers in tracking and analyzing behavioral modifications, such as obesity treatment, smoking cessation, and stress management. The platform allows healthcare providers to seamlessly integrate its software solution into existing electronic medical records systems, creating a physician-centric hub that supports wellness regimens for patients while optimizing billing processes for providers. By facilitating effective patient-physician engagement and ongoing communication, PrescribeWell aims to enhance patient outcomes in health management, disease prevention, and lifestyle modifications. The company was incorporated in 2012.
TowerView Health
Seed Round in 2015
TowerView helps the 1 in 3 Americans with a chronic illness manage multiple medications. TowerView’s patients receive pre-filled medication trays that fit into a connected pillbox like a K-Cup into a Keurig coffee machine. Their pillbox can sense when patients forget a dose and automatically sends a text or phone reminder. Unlike other smart pillboxes, they send patients pre-filled medication trays sourced from a pharmacy so patients never have to fill their own pillbox and they work directly with nurses​ to target outreach for non-adherent patients. TowerView is rolling out with Independence Blue Cross in January 2015 and are in advanced discussions with numerous other health plans.
Atrin Pharmaceuticals
Pre Seed Round in 2015
Atrin Pharmaceuticals LLC is a biopharmaceutical company based in Doylestown, Pennsylvania, focused on the discovery and development of innovative cancer treatments. Founded in 2011, the company is developing its lead drug candidates, ATRN-502, a p53 activator, and ATRN-507, a dual ligand that selectively targets cancer cells. Atrin is also advancing a proprietary platform called Atrize, which utilizes phenotypic FACS-based screening for rapid identification of effective drug candidates and evaluation of personalized medicine approaches. The company's research aims to address cancers linked to synthetic lethality and deregulated DNA damage response, with a focus on creating treatments that are effective against cancer cells while minimizing impact on healthy cells. Through its innovative methodologies, Atrin Pharmaceuticals seeks to change the landscape of cancer therapy.
CloudMine
Series A in 2015
CloudMine is a mobile backend-as-a-service (mBaaS) provider that focuses on enhancing healthcare mobility and patient health. The company offers a platform that facilitates object-based data storage and file storage, along with capabilities for sending push notifications and messages, thereby improving communication with users. By streamlining the development process, CloudMine enables healthcare and life science organizations to efficiently operationalize data through application development, analytics, and workflows. The platform is designed to support the creation of secure, interoperable, and scalable healthcare applications, significantly reducing development time and costs while eliminating the need for ongoing maintenance and management of mobile applications. Its mobile-optimized infrastructure and suite of prefabricated web services accelerate app development by up to 70%, standardizing mobility tools across various business units for improved efficiency.
Prescription Advisory Systems & Technology
Debt Financing in 2015
Prescription Advisory Systems & Technology, Inc. is dedicated to enhancing the management of chronic pain and mitigating the risks associated with the abuse of controlled substances through its innovative software, PASTRx. Established in 2013 and based in Jenkintown, Pennsylvania, the company addresses the critical issue of prescription medication overdoses, which have become the leading cause of accidental death in the United States. PASTRx is designed to assist healthcare providers in identifying patients who can safely receive controlled substances while flagging those who may need more complex treatment options. The software integrates data from multiple sources, offering features such as patient risk assessment, auditability, and institutional oversight, all within a user-friendly interface. This comprehensive approach aims to protect both patients and healthcare providers, ensuring safer prescribing practices.
Essential Medical
Seed Round in 2014
Essential Medical, Inc. is a medical device company based in Malvern, Pennsylvania, that specializes in developing femoral artery vascular closure devices. Founded in 2010, the company focuses on sealing femoral punctures that occur after diagnostic and interventional cardiac catheterization procedures. Essential Medical has created two primary closure devices, including MANTA, which is specifically designed to address large bore punctures ranging from 10 to 24 French. These devices are particularly relevant for procedures such as transcatheter aortic valve replacement (TAVR), abdominal aortic aneurysm repair (AAA/PVAR), and balloon aortic valvuloplasty (BAV). The innovations from Essential Medical aim to fulfill a significant need in interventional cardiology by providing efficient closure solutions that minimize complications for patients. Since October 2018, the company operates as a subsidiary of Teleflex Incorporated.
InstaMed
Venture Round in 2014
InstaMed Communications, LLC, founded in 2004 and headquartered in Philadelphia, Pennsylvania, operates a healthcare payments network that connects providers, payers, and consumers through a unified cloud-based platform. The company offers several products, including InstaMed Online for Providers and InstaMed Online for Payers, both of which facilitate secure management of healthcare payment transactions with role-based security. Additionally, InstaMed Connect integrates healthcare payments into existing IT applications via APIs. By streamlining electronic transactions and consolidating payment processes, InstaMed aims to reduce the risks and complexities associated with multiple payment vendors, ultimately enhancing consumer satisfaction and enabling providers to collect payments more efficiently. As of 2019, InstaMed operates as a subsidiary of JPMorgan Chase Bank, National Association.
Mitochon Pharmaceuticals
Seed Round in 2014
Mitochon Pharmaceuticals, Inc. is a biotechnology company established in 2014 and based in Blue Bell, Pennsylvania. The company is dedicated to developing drugs that target mitochondrial function, aiming to address significant unmet medical needs in treating serious diseases. Its primary focus is on neurodegenerative and neuromuscular disorders, including Huntington's disease, Alzheimer's disease, Parkinson's disease, Duchenne muscular dystrophy, and epilepsy, among others. Mitochon is also exploring potential therapies for metabolic disorders related to over-nutrition, such as diabetes and obesity. The company's research is grounded in the understanding that various diseases are linked to mitochondrial dysfunction, and by correcting these malfunctions, Mitochon seeks to pave the way for innovative disease-modifying therapies. The leadership team comprises experienced industry professionals with a strong commitment to advancing breakthrough drug therapies for conditions with limited treatment options.
Yorn LLC is a real-time feedback and engagement platform based in Philadelphia, Pennsylvania, primarily serving the healthcare sector. Founded in 2008, the platform empowers patients and consumers to provide immediate feedback on their experiences through various digital devices, such as smartphones, tablets, and laptops. This feedback allows healthcare providers and payers to identify issues and implement necessary operational changes to enhance patient experience, satisfaction, and compliance with care plans. In addition to healthcare, Yorn also caters to the hospitality, business, enterprise, meetings and events, and automotive sectors, helping organizations understand and improve customer experiences through actionable insights derived from authentic consumer feedback.
Photosonix Medical
Seed Round in 2014
Photosonix Medical is a company based in Ambler, Pennsylvania, focused on developing innovative skincare treatments for chronic bacterial infections, particularly in the context of moderate to severe acne. The company has created CLENSâ„¢, a device that synergistically combines low-level ultrasound stimulation with blue light energy to effectively target biofilms, which are often responsible for persistent skin issues. By offering a home-use treatment option, Photosonix Medical aims to empower users to manage their acne while preventing permanent skin scarring. The primary audience for its products includes dermatologists and primary care physicians who are involved in prescribing effective acne treatments.
Stabiliz Orthopaedics
Seed Round in 2014
Stabiliz Orthopaedics, LLC, founded in 2009 and based in Exton, Pennsylvania, specializes in the development and distribution of orthopedic devices. The company focuses on creating innovative enhancements to existing orthopedic medical technologies, utilizing FDA-approved methods. Their primary aim is to improve clinical outcomes and simultaneously reduce costs for healthcare systems, addressing the challenges faced by both patients and providers in the orthopedic field.
Advent Therapeutics
Seed Round in 2014
Advent Therapeutics is a pharmaceutical company based in Lumberville, Pennsylvania, dedicated to developing therapies for micro-orphan applications, specifically targeting serious unmet medical needs in neonatal and pediatric populations. The company focuses on legacy drugs aimed at treating disorders in newborn infants, particularly those in intensive care units. By creating prenatal, neonatal, and pediatric medications, Advent Therapeutics enables healthcare professionals to provide advanced care for vulnerable patients, addressing critical gaps in existing treatment options for this underserved demographic.
Vy Corporation
Seed Round in 2014
Vy Corporation is a software development company based in Wayne, Pennsylvania, that specializes in shape detection and object analysis software for the medical imaging market. The company offers CytoSavvy.com, a cloud-based image analysis and data collection service that enables users to upload and analyze images, particularly useful for identifying clusters of cells in liver and kidney biopsies using its patented CellQuantâ„¢ search technology. In addition, Vy Corporation provides VectorSavvy.com, which grants users access to advanced image analysis tools for loading images and viewing results, and it also develops custom projects tailored to specific client needs. The company's mission is to assist pathologists and medical researchers in efficiently identifying and analyzing complex cell structures, enhancing the reliability of data for research and diagnostics.
Cro Analytics
Seed Round in 2014
CRO Analytics, LLC specializes in providing data assessment tools and services tailored for sponsors and contract research organizations. The company has developed Performer, a cloud-based clinical trial performance system that includes a trial assessment platform offering in-trial alerts. This platform enables clinical research executives and management teams to enhance research quality, efficiency, and overall performance while achieving cost savings. By utilizing a proprietary validated process, CRO Analytics collects, analyzes, and reports on quality performance indicators in outsourced clinical research. The platform is designed to deliver insights into clinical research performance by capturing thousands of assessments from biopharma and service provider personnel directly involved in outsourced clinical research. Incorporated in 2011 and based in New Hope, Pennsylvania, CRO Analytics stands out with its ability to provide objective, validated performance data across various metrics, including service provider, sponsor, region, study type, phase, functional area, and therapeutic area.
HealthQX, founded in 2012 and based in King of Prussia, Pennsylvania, specializes in value-based payment analytic software solutions tailored for health plans and providers. The company's primary offering, ClarityQx, is a comprehensive analytics platform designed to facilitate the design, implementation, and ongoing performance monitoring of various payment models, including episodic, bundled, and accountable care arrangements. This platform provides users with drill-down dashboards that enhance provider engagement and streamline contract negotiation processes. By enabling quick access to critical payment analytics, HealthQX aims to improve consumer care and reduce medical costs within the healthcare industry.
MemVu, Inc. specializes in brain health training solutions designed for individuals and families. The company offers a unique platform, MemVu.com, which allows users to upload personal photos to create customized brain games and exercises aimed at enhancing cognitive function. This innovative approach not only facilitates brain fitness but also fosters family involvement in the care of individuals with various brain health conditions. MemVu's offerings are utilized by healthcare professionals, including physicians, social workers, and psychologists, as well as institutions like hospitals, rehabilitation centers, and assisted living facilities, to support patient care and engagement. Founded in 2008, MemVu is headquartered in Yardley, Pennsylvania.
Grand Round Table
Seed Round in 2014
Grand Round Table Inc. is a developer of clinical decision support tools aimed at enhancing diagnostic accuracy for healthcare providers. The company's flagship system, Grand Round Table, integrates with electronic health records to assist doctors in diagnosing patients by comparing their cases against a comprehensive database of deidentified health records, case reports, and evidence-based medical literature, including resources from the University of Pennsylvania. This technology enables physicians to access insights from previous cases, facilitating quicker and more informed treatment decisions for complex patients. By streamlining the decision-making process, Grand Round Table helps hospitals and clinics reduce unnecessary tests, ineffective treatments, and consultations, ultimately saving time and costs in patient care. Established in 2011, the company is headquartered in Philadelphia, Pennsylvania.
Essential Medical
Seed Round in 2014
Essential Medical is a family owned & operated business that was started in 1985. We are a broad based supplier of home medical and health related products designed with the needs of the user in mind. Within this online website you will find many different product options to meet a variety of life styles and physical conditions. If you are a home medical equipment dealer and would like to be set up to order Essential products, please click on the Prospective Dealers tab. If you would like to purchase products for yourself, family member or friend, our fine products are available through your local medical equipment dealer or pharmacy. Please consult the yellow pages of your local telephone book under Hospital and Medical Equipment.
BioDetego
Seed Round in 2014
BioDetego is focused on advancing cancer treatment through its innovative biomarker test, VASPfore, which is designed to optimize the selection of chemotherapy protocols. This test assesses the metastatic risk in colorectal cancer patients, allowing healthcare providers to identify high-risk individuals who are likely to benefit from chemotherapy while sparing low-risk patients from unnecessary and potentially harmful treatments. By providing actionable insights, VASPfore aims to improve patient outcomes and enhance the efficiency of cancer management. BioDetego anticipates significant cost savings for payors, estimating reductions of over $150 million annually in treatment expenses. The company is led by David Zuzga, Ph.D., and Giovanni M. Pitari, M.D., Ph.D., both of whom bring extensive expertise in cell and molecular biology and translational oncology, respectively.
Clutch
Venture Round in 2013
Clutch serves as a customer marketing platform for business-to-consumer brands. It provides traditional marketing CRM, loyalty, gift card, mobile, email, and direct mail solutions. The company was created to help businesses succeed in an evolving marketing landscape. Since 2012, they have continued to grow their platform into an innovative, data-centric marketing solution with one focus that empowering brands with the best technology so that they can identify, understand and motivate their customers.
OrthogenRx
Seed Round in 2013
OrthogenRx is a commercial-stage product development company focused on orthopedic medical devices aimed at treating musculoskeletal conditions, particularly knee joint pain. The company's primary product is an injection designed to lubricate the knee joint and alleviate mild to moderate pain for patients who have not adequately responded to conservative treatments. OrthogenRx employs a business model that leverages exclusive supply and license agreements for products available outside the United States, while also pursuing generic product approval domestically. This approach aims to reduce healthcare costs significantly by utilizing existing regulations for abbreviated approval of generic devices, similar to the process for generic drugs. By providing safe and effective non-surgical alternatives, OrthogenRx addresses the needs of patients seeking relief from joint pain.
ZSX Medical
Series A in 2013
ZSX Medical, LLC is a medical device development company based in Philadelphia, Pennsylvania, established in 2009. It specializes in creating bio-absorbable products for internal closure in minimally invasive surgeries. The company is focused on its flagship product, Zip-stitch, a surgical closure system designed to facilitate challenging surgical closures quickly and effectively. This device aims to enhance surgical efficiency by reducing operative time and minimizing complications such as infection, tissue adhesion, and dehiscence, compared to traditional sutures or staples. By improving surgical outcomes and reducing healthcare costs, ZSX Medical seeks to benefit both hospitals and patients.
Relmada Therapeutics
Series A in 2012
Relmada Therapeutics, Inc. is a clinical-stage biotechnology company based in New York, focused on developing innovative treatments for central nervous system (CNS) diseases. Established in 2004, the company is primarily working on its lead product candidate, d-Methadone, which is undergoing Phase II clinical trials for conditions such as major depressive disorder and neuropathic pain. In addition to d-Methadone, Relmada is developing LevoCap ER, a sustained-release formulation of levorphanol designed to be abuse-resistant; BuTab, an oral formulation of buprenorphine; and MepiGel, a topical formulation of mepivacaine intended for localized anesthesia. The company's research aims to address significant unmet medical needs in CNS disorders and improve patient outcomes.
Annovis Bio
Seed Round in 2012
Annovis Bio, Inc. is a clinical-stage pharmaceutical company based in Berwyn, Pennsylvania, specializing in the development of treatments for neurodegenerative disorders, particularly Alzheimer's disease and Parkinson's disease. The company is advancing several compounds in clinical trials, with its lead candidate, ANVS401, currently in Phase 2a trials aimed at treating Alzheimer’s disease, Parkinson’s disease, and other chronic neurodegenerative conditions. Additionally, Annovis is developing ANVS405, which focuses on providing neuroprotection following traumatic brain injuries and strokes, and ANVS301, which is in Phase I trials designed to enhance cognitive function in later stages of Alzheimer’s disease and dementia. Founded in 2008, Annovis Bio is dedicated to creating innovative therapies to address the challenges posed by these debilitating diseases.
Stabiliz Orthopaedics
Seed Round in 2012
Stabiliz Orthopaedics, LLC, founded in 2009 and based in Exton, Pennsylvania, specializes in the development and distribution of orthopedic devices. The company focuses on creating innovative enhancements to existing orthopedic medical technologies, utilizing FDA-approved methods. Their primary aim is to improve clinical outcomes and simultaneously reduce costs for healthcare systems, addressing the challenges faced by both patients and providers in the orthopedic field.
EyeIC
Venture Round in 2012
EyeIC, Inc. is a medical technology company focused on developing and commercializing imaging technologies for eye care applications. Based in Wayne, Pennsylvania, EyeIC serves eye care professionals and clinics by offering the MatchedFlicker device, which monitors the onset and progression of glaucoma through change detection in time series retinal photographs. The technology aligns and registers images taken at different times, creating a superimposed view that aids in accurate diagnosis. Additionally, EyeIC's software includes an easy-to-use application that streamlines image processing, interpretation, and reporting, facilitating the detection of various retinal conditions such as diabetic retinopathy and retinopathy of prematurity. Established in 2004, EyeIC aims to simplify workflows for clinicians and enhance patient care in the field of ophthalmology.
Prezacor
Seed Round in 2012
Prezacor, Inc. specializes in developing and marketing innovative pain management solutions, with its primary product being the Energezeâ„¢ Patch. This patch utilizes the company's proprietary Energezicsâ„¢ technology, designed to alleviate both acute and chronic pain without the use of medication. It features a unique broad-area surface electrode made from a specialized formula that absorbs and resonates with a variety of naturally occurring waveforms present in living tissues. By delivering these waveforms, the patch aims to reduce pain and discomfort across multiple areas of the body, providing a non-invasive alternative for pain relief.
Essential Medical
Seed Round in 2011
Essential Medical is a family owned & operated business that was started in 1985. We are a broad based supplier of home medical and health related products designed with the needs of the user in mind. Within this online website you will find many different product options to meet a variety of life styles and physical conditions. If you are a home medical equipment dealer and would like to be set up to order Essential products, please click on the Prospective Dealers tab. If you would like to purchase products for yourself, family member or friend, our fine products are available through your local medical equipment dealer or pharmacy. Please consult the yellow pages of your local telephone book under Hospital and Medical Equipment.
Essential Medical
Seed Round in 2010
Essential Medical, Inc. is a medical device company based in Malvern, Pennsylvania, that specializes in developing femoral artery vascular closure devices. Founded in 2010, the company focuses on sealing femoral punctures that occur after diagnostic and interventional cardiac catheterization procedures. Essential Medical has created two primary closure devices, including MANTA, which is specifically designed to address large bore punctures ranging from 10 to 24 French. These devices are particularly relevant for procedures such as transcatheter aortic valve replacement (TAVR), abdominal aortic aneurysm repair (AAA/PVAR), and balloon aortic valvuloplasty (BAV). The innovations from Essential Medical aim to fulfill a significant need in interventional cardiology by providing efficient closure solutions that minimize complications for patients. Since October 2018, the company operates as a subsidiary of Teleflex Incorporated.
SkillSurvey
Seed Round in 2007
SkillSurvey Inc. offers cloud-based reference checking and credentialing solutions designed to enhance the hiring process for employers. Founded in 2001 and based in Berwyn, Pennsylvania, the company provides various products, including SkillSurvey Reference, which automates the reference checking process, and Hire 360, an online assessment tool that predicts a candidate's job performance. Additionally, SkillSurvey Credential OnDemand facilitates immediate online responses from applicants and references, while SkillSurvey Source aids in candidate sourcing through referrals. The company's technology is particularly beneficial for sectors such as healthcare, higher education, staffing, and retail, enabling organizations to efficiently verify candidate qualifications and skills. By leveraging data-driven insights, SkillSurvey's patented solutions help clients make informed hiring decisions, ultimately improving business performance and employee retention.
Ceptaris Therapeutics
Series B in 2006
Ceptaris Therapeutics, Inc. is a privately held specialty pharmaceutical company focused on developing a proprietary gel formulation of mechlorethamine hydrochloride for treating early-stage (stages I-IIA) mycosis fungoides, a form of Cutaneous T-Cell Lymphoma (CTCL). If approved, this investigational drug would be the first topical mechlorethamine product available for managing the signs and symptoms of this rare cancer. In addition to this primary focus, Ceptaris is also involved in developing other therapeutic products, including YT-1006, an NMDA antagonist aimed at treating neuropathic pain while minimizing side effects associated with NMDA. The company's innovative approaches enable healthcare professionals to address both dermatological and central nervous system disorders effectively.
Bionano Genomics
Seed Round in 2006
Bionano Genomics, Inc. is a biotechnology company focused on genome mapping and analysis. It develops and markets the Saphyr system, an advanced platform designed for ultra-sensitive and specific detection of structural variations in DNA, such as insertions, deletions, and translocations, which are often linked to genetic disorders and diseases, including cancer. The Saphyr system employs optical genome mapping technology, allowing for direct visualization and analysis of long DNA molecules without relying on sequencing. This capability provides researchers and clinicians with critical insights into the structural variations within genomes, enhancing the understanding of disease mechanisms and supporting the development of personalized treatment strategies. Bionano Genomics also offers essential reagents and data solutions, including Bionano prep kits, labeling kits, and software tools for comprehensive experiment management. Its products are primarily sold to academic and governmental research laboratories, as well as pharmaceutical, biotechnology, and contract research organizations across multiple regions, including North America, Europe, and Asia. Founded in 2003 and headquartered in San Diego, California, the company was previously known as BioNano Genomics, Inc. until its name change in July 2018.
SFA Therapeutics, Inc. is a development-stage bio-pharmaceutical company located in Jenkintown, Pennsylvania. The company specializes in creating drugs derived from microbiome-derived metabolites aimed at treating chronic inflammatory diseases and cancer. By harnessing compounds discovered in the human microbiome, SFA Therapeutics seeks to provide innovative therapeutic solutions for various medical conditions, including autoimmune diseases and liver disorders.