BioGenerator

BioGenerator is a non-profit venture development organization affiliated with BioSTL, focused on fostering the growth of sustainable bioscience companies in the St. Louis region. It specializes in pre-seed and seed investments, typically ranging from $0.01 million to $0.25 million, targeting startups in various sectors including healthcare services, plant sciences, medical equipment, diagnostics, therapeutics, and alternative energy resources. In addition to financial support, BioGenerator offers shared laboratory space equipped with specialized tools and provides comprehensive management assistance to its portfolio companies. The organization often takes the lead in pre-seed and seed investments, collaborating with local angel investors and economic development groups to facilitate follow-on funding. Established in 2003, BioGenerator plays a pivotal role in strengthening the bioscience ecosystem in the St. Louis area.

Charlie Bolten

Senior Vice President

Tom Cohen

Director

Eric Gulve

President

Trey Suntrup

Principal

Crystal Winkeler

Managing Director

83 past transactions

ARTA Bioscience

Grant in 2012
ARTA Bioscience, Inc is developing new therapeutics for prostate cancer and inflammatory diseases. Current treatments for prostate cancer are insufficient and the disease is the second leading cause of cancer deaths among American men. ARTA's technology involves an entirely different approach to combating disease compared to traditional treatments. In addition to prostate cancer, the company's technologies may be used to target other important proteins in the nuclear receptor class. The company has established operations at the BioGenerator Accelerator Labs. ARTA's technology was developed by Dr. Marc Diamond at Washington University.

RNAgri

Seed Round in 2015
RNAgri designs an innovative technology that produces ribonucleic acid. The company's technology addresses some of the challenges to the mass production of exogenous RNAi-based products using a large scale fermentation process, enabling farmers to protect and improve their crops and cattle. The company was founded in 2011 and is headquartered in St Louis, Missouri.

Arch Innotek

Venture Round in 2019
Arch Innotek, LLC, a biotech company, engages in engineering microorganisms to produce natural ingredients that are beneficial to human and animal health. It focuses on the development of high-value molecules for food, feed, pharmaceutical, and cosmetics industries. The company also provides HPLC analysis, LC-MS analysis, protein purification, fermentation for strain optimization, and vector construction for protein expression and molecular cloning. Arch Innotek, LLC was incorporated in 2013 and is based in St. Louis, Missouri.

Covercress

Series A in 2015
CoverCress is a biotechnology company that focuses on research and development of renewable fuel and livestock feed. It specializes in producing an oilseed crop for food, bioenergy, and cattle feed. It specializes in the fields of agriculture, biotechnology, plants, genetics, cover crop, and precision agriculture. CoverCress was founded in 2013 by Jerry Steiner and Dr. Tim Ulmasov and is headquartered in St. Louis Missouri.

Euphrates Vascular

Venture Round in 2010
As of January 8, 2019, Pulse Therapeutics, Inc. was acquired by Ichor Vascular, Inc. Pulse Therapeutics, Inc., a medical technology company, develops magnetically-enhanced diffusion (MED) system for the treatment of stroke, heart, and other diseases. Its MED system is used to harness magnet-based technology to dissolve blood clots faster than current modalities. The company also provides MED MicroBeads that are designed to convey physician-selected agents faster to the blood clot; intravenously administered after thrombolysis therapy is initiated; and mechanical adjunct to standard of care IV thrombolysis. In addition, it offers touch screen operated MED Workstation. Pulse Therapeutics, Inc. was incorporated in 2008 and is based in St. Louis, Missouri.

Bacterioscan

Series A in 2013
BacterioScan, Inc., a medical device company, designs products to diagnose and treat infectious diseases. The company offers 216Dx UTI System for detecting bacteria indicative of a urinary tract infection (UTI) in clinical urine samples, as well as identifying appropriate antibiotic treatment. Its product pipeline also includes 216R Antibiotic Susceptibility Testing System that detects bacterial infection, determines its resistance to a range of antibiotics, and provides clinicians with patient-specific antimicrobial resistance profiles. The company was incorporated in 2008 and is based in St Louis, Missouri.

Impetus AG

Seed Round in 2021
Impetus Agriculture focuses on developing multiple topical or transgenic insect control products. Products that are safe, effective, and sustainable. Products that are not subject to the same insect resistance that has developed in current commercial products.

Nitrogenics

Seed Round in 2015
Nitrogenics is a plant biotechnology company providing research analysis on nitrogen fixation in crop plants. Nitrogenics' services include data related to plant enzymes that are inserted in the genome of tobacco, enabling researchers to get to research on plants that absorbs nitrogen directly from the atmosphere, rather than from fertilized soil.

Antegrin Therapeutics

Seed Round in 2015
Antegrin Therapeutics, LLC, is a drug discovery and development company focused on the development of novel therapies for fibrotic diseases. Our lead program aims to develop a treatment for idiopathic pulmonary fibrosis, a progressive, life-threatening condition that currently has no FDA-approved medication.

SynerZ Medical

Seed Round in 2015
SynerZ Medical, Inc. develops medical device for the treatment of obesity and type 2 diabetes. The company was incorporated in 2013 and is based in St. Louis, Missouri.

S4

Seed Round in 2015
S4 is a technology service company that provides risk management solutions to ensure food production. It also develops index-based coverage to transfer the agriculture industry's volatilities to the financial markets, through OTC-derivatives contracts. The company offers products and services are used by a broad range of customers including large growers, crop protection and seeds suppliers, crop insurance providers, banking, and commodity exchanges. S4 integrates the harvest information with a planting plan, seed density, and soil analysis. They had developed a decision-making geo-referenced platform for the agricultural producer. They seek to improve the decision-making process in complex environments to collaborate in the global challenge of generating quality food for humanity. S4 was founded on 2011 and is headquartered in Buenos Aires, Argentina.

YourBevCo

Venture Round in 2015
YourBevCo, LLC is a beverage device company developing a pipeline of innovative, disruptive consumer devices that safely and effectively remove problematic ingredients from beverages that are known to cause allergic or sensitivity reactions.

Euclises Pharmaceuticals

Venture Round in 2015
Euclises Pharmaceuticals, Inc is developing novel pain and cancer medications that offer superior safety margins compared to existing drugs. The company is based on new inventions from Dr. John Talley, the most accomplished medicinal chemist in the world. Dr. Talley previously invented Celebrex and seven other approved drugs. New compounds from Euclises will offer both improved efficacy and safety relative to existing therapies. Euclises is located at the BioGenerator Accelerator Labs.

Canopy Biosciences

Private Placement in 2017
Canopy Biosciences is biotechnological company that provides products and services for gene editing and personalized medicine. The gene editing technology is called TUNR and targets translation elongation by inserting polyA tracks into targeted coding regions of the genome. This change then decreases the levels of mRNA transcribed from the gene and therefore suppresses protein expression. It was initially developed by Professor Sergej Djuranovic at Washington University School of Medicine and Professor Rachel Green from Johns Hopkins University. Canopy Biosciences was formed in 2016 and is headquartered in Saint Louis, Missouri.

Cadre Bioscience

Seed Round in 2020
Cadre Bioscience, LLC develops therapeutics for human diseases. The company was founded in 2019 and is based in Saint Louis, Missouri.

Cofactor Genomics

Seed Round in 2015
Cofactor Genomics is a Predictive Immune Modeling company driven to remove the barriers that have prohibited the advancement of true precision medicine. Cofactor is enabling the industry to move beyond isolated, single-analyte biomarkers to powerful multidimensional biomarkers using Health Expression Models. Through their molecular, informatic, and database tools, and one of the first CAP-certified, clinical RNA sequencing laboratories, Cofactor enables their partners to deliver more expedient, cost effective, and successful clinical trials.

Atomation

Seed Round in 2018
Atomation, founded in Tel Aviv and now with headquarters in Saint Louis, Missouri, is a business-to-business solutions company that uses an innovative Internet of Things (IoT) platform to connect existing, in-field, legacy objects and assets to the internet. Focused on making the data gathered by sensors into useful and actionable information, Atomation solves problems differently with affordable and simple solutions that allow businesses to transform operations and optimize their bottom line.

Antegrin Therapeutics

Seed Round in 2013
Antegrin Therapeutics, LLC, is a drug discovery and development company focused on the development of novel therapies for fibrotic diseases. Our lead program aims to develop a treatment for idiopathic pulmonary fibrosis, a progressive, life-threatening condition that currently has no FDA-approved medication.

Array Bridge

Grant in 2012
Array Bridge provides quality products and services for the pharmaceutical and biotechnology industry. Products include antibody arrays for biosimilar and antibody-drug conjugate (ADC) three-dimensional (3-D) conformational comparability analysis, ELISA kits for Host Cell Proteins including CHO and E. coli-derived biologics. Services include antibody production; Host Cell Protein and binding-based bioassay method qualification and validation; 1-D and 2-D gel analysis of process-related impurities; Western Blot analysis of HCPs; Residual DNA and Protein A analysis.

Confluence Life Sciences

Series B in 2015
Confluence Life Sciences, Inc. operates as a KINect technology based company that focuses on drug design to identify mechanistically novel drugs. It develops a portfolio of projects to address unmet medical needs in caner and chronic inflammatory diseases. The company focuses on designing and developing kinase inhibitors that target key enzymes involved in the regulation of cancer growth, survival and metastasis, or in the modulation of chronic inflammation. Its KINect technology platform enables the identification and development of new protein kinase drugs. Confluence Life Sciences, Inc. was founded in 2010 and is based in Saint Louis, Missouri. As of August 3, 2017, Confluence Life Sciences, Inc. operates as a subsidiary of Aclaris Life Sciences, Inc.

Canopy Biosciences

Series A in 2018
Canopy Biosciences is biotechnological company that provides products and services for gene editing and personalized medicine. The gene editing technology is called TUNR and targets translation elongation by inserting polyA tracks into targeted coding regions of the genome. This change then decreases the levels of mRNA transcribed from the gene and therefore suppresses protein expression. It was initially developed by Professor Sergej Djuranovic at Washington University School of Medicine and Professor Rachel Green from Johns Hopkins University. Canopy Biosciences was formed in 2016 and is headquartered in Saint Louis, Missouri.

Kypha

Seed Round in 2012
Kypha Inc. discovers, develops, and commercializes in-vitro diagnostic biomarker tests within the inflammation and autoimmune space. It offers COMP ACT System, an inflammation and immune diagnostics to improve the way human health and disease activity is monitored and treated in patients. The company’s product is used in various applications across a range of indications that include lupus, stroke, traumatic brain injury, preeclampsia, infection, kidney disease, and transplant rejection. Kypha Inc. was formerly known as Kentucky Pharmaceuticals, Inc. The company was incorporated in 2009 and is based in St. Louis, Missouri.

Tansna Therapeutics

Seed Round in 2014
Tansna Therapeutics, Inc., a drug discovery and development company, develops and commercializes oral drugs to treat epilepsy. The company focuses on novel therapies for the treatment of central nervous system disorders. Its products under pipeline include oral anticonvulsant agent that reduces seizure frequency in patients with epilepsy. The company was founded in 2010 and is based in St. Louis, Missouri.

Start Right

Seed Round in 2019
Start Right commercializes convenient, protein-packed, nutritional breakfast foods.

Indalo Therapeutics

Seed Round in 2013
Indalo Therapeutics is a preclinical-stage biotechnology company dedicated to improving the lives of patients suffering from debilitating fibrotic diseases. Founded on groundbreaking scientific discoveries and leveraging cutting-edge insight into the molecular drivers of aberrant scarring, Indalo is harnessing the collective experience of a seasoned team of pharmaceutical scientists and executives to tackle some of the most urgent unmet medical needs in the fibrosis space.
Apertus Pharmaceuticals is an Active Pharmaceutical Ingredient, or API, manufacturing company targeting dosage form manufacturing companies within the pharmaceutical industry. Apertus Pharmaceuticals provides controlled substance APIs, non controlled substance APIs, and intellectual property to the pharmaceutical market. In addition, Apertus Pharmaceuticals utilizes the philosophies of Green Chemistry as outlined by the FDA and will target higher purity standards than those set by the current standard setting authorities. Apertus is led by CEO Rick Ryan, Ph.D. and CSO David Gindelberger, Ph.D.

Prostate Management Diagnostics

Series A in 2014
Prostate Management Diagnostics creates tests and develops a fluid-based screening tool. It specializes in the fields of health diagnostics, medical, and healthcare. It was founded in 2014 and headquartered in San Francisco, California.

Graematter

Seed Round in 2013
The original concept for the regulatory intelligence system was conceived by Graematter’s founder, Melissa Walker, in 1999. An early-stage, pre-prototype version of the system was first created in 2000. It began as an effort to simply improve the ability to locate key information. As the volume of regulatory information began to expand dramatically and as the regulatory environment became increasingly complex, it continued to evolve. Over time, Ms. Walker developed an intelligence system that provided simple, lower cost ways to better retrieve and analyze large amounts of data that reside in numerous locations. The evolving system has been in continuous use in actual applications during that time as its capabilities were expanded and improved.

Journeys Metabolic

Seed Round in 2019
Readout is a digital health company with a mission to help patients better manage their own health by providing novel, clinically-backed tools to easily measure health biomarkers. Biosense was launched in early 2020 as a Class 1 medical device in the clinical, consumer, and research market after a successful clinical trial. As the only clinically-backed breath ketone measurement handheld device+app, Biosense provides full-day feedback of ketosis with unlimited measurements leading to protocol adherence and better outcomes. Biosense is used by obesity and diabetes clinics for in-home testing of ketosis, pharma and academic trials, as well as DTC via https://mybiosense.com.

Omniose

Seed Round in 2019
VaxNewMo is an early stage biotechnological company developing next-generation conjugate vaccines against infectious diseases using our proprietary in vivo conjugating technology.

Benson Hill

Seed Round in 2014
Benson Hill is a crop improvement company that unlocks the natural diversity of plants and empowers innovators with a revolutionary crop design platform to develop healthier and more sustainable food and ingredients. Benson Hill empowers innovators to develop more healthy, flavorful, and sustainable food by unlocking the natural genetic diversity of plants. Benson Hill’s CropOS™ platform combines machine learning and big data with breeding techniques and plant biology to drastically accelerate and simplify the product development process.

Bacterioscan

Venture Round in 2019
BacterioScan, Inc., a medical device company, designs products to diagnose and treat infectious diseases. The company offers 216Dx UTI System for detecting bacteria indicative of a urinary tract infection (UTI) in clinical urine samples, as well as identifying appropriate antibiotic treatment. Its product pipeline also includes 216R Antibiotic Susceptibility Testing System that detects bacterial infection, determines its resistance to a range of antibiotics, and provides clinicians with patient-specific antimicrobial resistance profiles. The company was incorporated in 2008 and is based in St Louis, Missouri.

Kalocyte

Seed Round in 2019
Kalocyte is a pre-clinical stage healthcare biotech startup company that provides artificial red blood cell substitutes used for trauma care related services. The company develops a demonstrated proof of concept for ErythroMer, a dried, bio-inspired artificial red blood cell envisioned for use when stored red blood cells are unavailable, undesirable, or in short supply. Kalocyte was founded in 2016 and is headquartered in Baltimore, Maryland.

Impetus AG

Seed Round in 2019
Impetus Agriculture focuses on developing multiple topical or transgenic insect control products. Products that are safe, effective, and sustainable. Products that are not subject to the same insect resistance that has developed in current commercial products.

Mobius Therapeutics

Venture Round in 2011
Mobius Therapeutics, LLC develops sterile injectable pharmaceutical products for ophthalmic applications in the United States. It offers Mitosol (mitomycin for solution) kit, an ophthalmic formulation of MMC that contains a closed-system transfer device and sponge tray enabling the safe reconstitution and transfer of MMC; and Amphadase, a hyaluronidase injection. The company serves ophthalmologists and their patients. It offers its products online. Mobius Therapeutics, LLC was founded in 2006 and is based in St Louis, Missouri.

Readout, Inc.

Private Placement in 2019
Readout, Inc. operates in the healthcare industry. The company was incorporated in 2018 and is based in St. Louis, Missouri.

Euclises Pharmaceuticals

Series A in 2014
Euclises Pharmaceuticals, Inc is developing novel pain and cancer medications that offer superior safety margins compared to existing drugs. The company is based on new inventions from Dr. John Talley, the most accomplished medicinal chemist in the world. Dr. Talley previously invented Celebrex and seven other approved drugs. New compounds from Euclises will offer both improved efficacy and safety relative to existing therapies. Euclises is located at the BioGenerator Accelerator Labs.

SentiAR

Seed Round in 2017
SentiAR, Inc. develops a platform for eventual FDA submission. Its software is used for 3-Dimensional cardiac holographic visualization; and converting CT, MRI, and real-time mapping outputs into a real-time holograms for clinicians. SentiAR, Inc. was incorporated in 2017 and is based in St. Louis, Missouri.

GeneriCo

Venture Round in 2015
GeneriCo is focused on developing and marketing niche generic pharmaceuticals that have been neglected by mid and large generic companies and also have an embedded drug delivery technology. The combination of neglected, technically challenging formulation, and economic size makes the GeneriCo pipeline not appealing to middle and large competitors, and too complex for tightly focused small generic companies.

SentiAR

Series A in 2021
SentiAR, Inc. develops a platform for eventual FDA submission. Its software is used for 3-Dimensional cardiac holographic visualization; and converting CT, MRI, and real-time mapping outputs into a real-time holograms for clinicians. SentiAR, Inc. was incorporated in 2017 and is based in St. Louis, Missouri.

Array Bridge

Seed Round in 2011
Array Bridge provides quality products and services for the pharmaceutical and biotechnology industry. Products include antibody arrays for biosimilar and antibody-drug conjugate (ADC) three-dimensional (3-D) conformational comparability analysis, ELISA kits for Host Cell Proteins including CHO and E. coli-derived biologics. Services include antibody production; Host Cell Protein and binding-based bioassay method qualification and validation; 1-D and 2-D gel analysis of process-related impurities; Western Blot analysis of HCPs; Residual DNA and Protein A analysis.

Aggio

Seed Round in 2019
Aggio is an information technology company that provides a cloud-based platform to provides solutions in marketing and sales on the agriculture industry. Its platform offers a marketing and sales analytics to help its clients in data-driven decision making by providing data harmonization and visualization. The company was founded in 2016 and headquartered in St. Louis Missouri.

Immunophotonics

Series A in 2015
ImmunoPhotonics, Inc. operates as a biotechnology company that engages in the development of a proprietary novel drug product for use in an in situ autologous cancer vaccine for the treatment of metastatic solid tumor cancers. The company was founded in 2008 and is based in St. Louis, Missouri.

Confluence Life Sciences

Series A in 2012
Confluence Life Sciences, Inc. operates as a KINect technology based company that focuses on drug design to identify mechanistically novel drugs. It develops a portfolio of projects to address unmet medical needs in caner and chronic inflammatory diseases. The company focuses on designing and developing kinase inhibitors that target key enzymes involved in the regulation of cancer growth, survival and metastasis, or in the modulation of chronic inflammation. Its KINect technology platform enables the identification and development of new protein kinase drugs. Confluence Life Sciences, Inc. was founded in 2010 and is based in Saint Louis, Missouri. As of August 3, 2017, Confluence Life Sciences, Inc. operates as a subsidiary of Aclaris Life Sciences, Inc.

Geneoscopy

Series B in 2021
Geneoscopy, LLC develops diagnostics using stool-derived eukaryotic RNA (seRNA) to prevent, detect, and guide treatment for gastrointestinal diseases. It uses its platform technology to develop a stool-based, multi-target RNA biomarker panel that identifies colorectal cancer by capturing the downstream effects of cancer-causing DNA mutations. The company also provides a diagnostic test that improves colorectal cancer screening compliance, facilitate early-stage detection of colorectal cancer neoplasms, and reduce morbidity and mortality associated with the disease. The company was founded in 2015 and is headquartered in Saint Louis, Missouri.

Healthy Bytes

Series A in 2019
Healthy Bytes, Inc. develops a software for personalized and expert nutritional counseling. It offers Healthy Bytes, a platform that connects physicians, employers, and patients to nutritional counseling. The company’s platform also helps users to book their private consultation, and consult registered dietitian online. Healthy Bytes, Inc. was founded in 2014 and is headquartered in Saint Louis, Missouri with an additional office in New York, New York.

PixelEXX Systems

Seed Round in 2008
PixelEXX Systems Inc. develops prototype imaging devices for diagnosing cancer. The products include nanoarrays that take images of molecular signals associated with cellular activity. PixelEXX Systems Inc. was founded in 2008 and is based in Saint Louis, Missouri.

CoverCress Inc.

Private Placement in 2018
CoverCress Inc. engages in developing, genetically improving, and commercializing field pennycress as an oilseed crop that is used to produces oil for industrial and renewable fuels, and meal for nutritious livestock feed. The company develops and grow a new cover crop based on the native plant pennycress. CoverCress Inc. was formerly known as Arvegenix Inc. and changed its name to CoverCress Inc. in November 14, 2018. The company was founded in 2013 and is based in Saint Louis, Missouri.

S4

Convertible Note in 2016
S4 is a technology service company that provides risk management solutions to ensure food production. It also develops index-based coverage to transfer the agriculture industry's volatilities to the financial markets, through OTC-derivatives contracts. The company offers products and services are used by a broad range of customers including large growers, crop protection and seeds suppliers, crop insurance providers, banking, and commodity exchanges. S4 integrates the harvest information with a planting plan, seed density, and soil analysis. They had developed a decision-making geo-referenced platform for the agricultural producer. They seek to improve the decision-making process in complex environments to collaborate in the global challenge of generating quality food for humanity. S4 was founded on 2011 and is headquartered in Buenos Aires, Argentina.

Immunophotonics

Series A in 2014
ImmunoPhotonics, Inc. operates as a biotechnology company that engages in the development of a proprietary novel drug product for use in an in situ autologous cancer vaccine for the treatment of metastatic solid tumor cancers. The company was founded in 2008 and is based in St. Louis, Missouri.

Accuronix Therapeutics

Seed Round in 2016
Accuronix Therapeutics, Inc. develops oncology therapies for pancreatic cancer. The company was founded in 2015 and is based in the United States.

Plastomics

Seed Round in 2017
Plastomics is a biotechnology startup that focuses in developing the next generation of crops by using chloroplast genetic engineering. Its technology platform is applicable to different crops and traits. Plastomics provides solutions for the many current industry challenges. The company was founded in 2016 and headquartered in St. Louis, Missouri.

RNAgri

Seed Round in 2012
RNAgri designs an innovative technology that produces ribonucleic acid. The company's technology addresses some of the challenges to the mass production of exogenous RNAi-based products using a large scale fermentation process, enabling farmers to protect and improve their crops and cattle. The company was founded in 2011 and is headquartered in St Louis, Missouri.

Benson Hill

Debt Financing in 2013
Benson Hill is a crop improvement company that unlocks the natural diversity of plants and empowers innovators with a revolutionary crop design platform to develop healthier and more sustainable food and ingredients. Benson Hill empowers innovators to develop more healthy, flavorful, and sustainable food by unlocking the natural genetic diversity of plants. Benson Hill’s CropOS™ platform combines machine learning and big data with breeding techniques and plant biology to drastically accelerate and simplify the product development process.

Companion Pharma

Seed Round in 2012
Companion Pharma is an animal health product development company that will develop innovative new formulations of drugs for use under prescription in companion animals. Companion will specifically target companion animal disease indications that have a high unmet treatment need and will provide 'pet friendly' drugs that are proven to work safely in the target species, are formulated in a way to provide ease of administration and are available in doses that meet the needs of the highly variable weight profile of companion animal pets.

Omniose

Grant in 2020
VaxNewMo is an early stage biotechnological company developing next-generation conjugate vaccines against infectious diseases using our proprietary in vivo conjugating technology.
Confluence Discovery Technologies is a drug discovery contract research organization (CRO) providing a variety of technical services including mechanistic enzymology, target validation and characterization, screening and assay development, biomarker development and measurement. The company offers its customers novel approaches to identification of kinase inhibitors along with decades of experience developing clinical candidates for this class. Founders were key scientific leaders in Pfizer's Inflammation Research Unit. Confluence is located at the BioGenerator Accelerator Labs.

MediBeacon

Venture Round in 2013
MediBeacon Inc. develops real-time kidney function monitoring solutions. It offers NIC-Kidney device to monitor glomerular filtration rate (mGFR) in the preclinical setting. The company also provides MediBeacon renal function system that uses an optical skin sensor combined with a proprietary agent that glows in the presence of light and provides clinicians with continuous real-time monitoring of a patient’s kidney function. In addition, it offers MediBeacon Pipeline, a portfolio of light-activated agents. MediBeacon Inc. was founded in 2012 and is based in St. Louis, Missouri.

GeneriCo

Debt Financing in 2013
GeneriCo is focused on developing and marketing niche generic pharmaceuticals that have been neglected by mid and large generic companies and also have an embedded drug delivery technology. The combination of neglected, technically challenging formulation, and economic size makes the GeneriCo pipeline not appealing to middle and large competitors, and too complex for tightly focused small generic companies.

MedAware Solutions

Venture Round in 2016
Medaware Solutions, Inc. provides a platform to connect healthcare teams. It offers mViva, a platform that enables payers and providers to engage with patients and their relatives throughout the continuum of care. The company’s platform also enables multi-disciplinary teams to interact in patient-centric threads for coordination of care, as well as allows patients and care teams to capture and share data through a secure HIPAA-compliant platform. Medaware Solutions, Inc. was incorporated in 2014 and is based in St. Louis, Missouri.

MedSocket

Seed Round in 2015
MedSocket of Missouri, Inc. provides health information technology solutions. It offers 1-CDS (1-Click Decision Support), a clinical decision support system; and 1-Search, a search engine that provides evidence-based information for clinicians. The company was founded in 2012 and is based in Columbia, Missouri.

Euclises Pharmaceuticals

Series A in 2015
Euclises Pharmaceuticals, Inc is developing novel pain and cancer medications that offer superior safety margins compared to existing drugs. The company is based on new inventions from Dr. John Talley, the most accomplished medicinal chemist in the world. Dr. Talley previously invented Celebrex and seven other approved drugs. New compounds from Euclises will offer both improved efficacy and safety relative to existing therapies. Euclises is located at the BioGenerator Accelerator Labs.

Adarza BioSystems

Seed Round in 2013
Adarza BioSystems is an early-stage medical diagnostics company developing a rapid and label-free biological assay platform for measuring clinical and point-of-care (POC) samples. In addition to performing sophisticated clinical tests within minutes, this technology potentially allowing hundreds of tests to be run simultaneously on a single chip. It was founded in 2008 and headquartered in St Louis, Missouri.

Healthy Bytes

Private Placement in 2019
Healthy Bytes, Inc. develops a software for personalized and expert nutritional counseling. It offers Healthy Bytes, a platform that connects physicians, employers, and patients to nutritional counseling. The company’s platform also helps users to book their private consultation, and consult registered dietitian online. Healthy Bytes, Inc. was founded in 2014 and is headquartered in Saint Louis, Missouri with an additional office in New York, New York.

CardiaLen

Series B in 2015
Cardialen, Inc., a medical device company that develops a therapy system that detects and treats atrial fibrillation, rapid ventricular tachycardia, and ventricular fibrillation. It offers an implantable device to restore normal heart rhythm and may reduce the potential for high-energy defibrillation shocks. The company was incorporated in 2008 and is based in Minneapolis, Minnesota.

Edis Solutions

Seed Round in 2014
Confluence gathers, filters, combines and presents the pharmaceutical intelligence you need. It turns manual into automatic, risk into reliability and wait into wow. With Confluence you start where it counts: crucial planning and decision-making. Skip the assembly, start with Confluence.

OpenCell Technologies

Private Placement in 2020
OpenCell Technologies, Inc. provides transfection tools to the life science industry. It offers an intracellular delivery platform and tools that enable life science industries to use difficult-to-transfect cells (primary and cancer stem cell cultures) in the development of cell-based analysis techniques and the discovery of new therapeutic cell-based therapies. OpenCell Technologies, Inc. was founded in 2008 and is based in Saint Louis, Missouri.

Kypha

Venture Round in 2014
Kypha Inc. discovers, develops, and commercializes in-vitro diagnostic biomarker tests within the inflammation and autoimmune space. It offers COMP ACT System, an inflammation and immune diagnostics to improve the way human health and disease activity is monitored and treated in patients. The company’s product is used in various applications across a range of indications that include lupus, stroke, traumatic brain injury, preeclampsia, infection, kidney disease, and transplant rejection. Kypha Inc. was formerly known as Kentucky Pharmaceuticals, Inc. The company was incorporated in 2009 and is based in St. Louis, Missouri.

Covercress

Venture Round in 2017
CoverCress is a biotechnology company that focuses on research and development of renewable fuel and livestock feed. It specializes in producing an oilseed crop for food, bioenergy, and cattle feed. It specializes in the fields of agriculture, biotechnology, plants, genetics, cover crop, and precision agriculture. CoverCress was founded in 2013 by Jerry Steiner and Dr. Tim Ulmasov and is headquartered in St. Louis Missouri.

MedSocket

Seed Round in 2014
MedSocket of Missouri, Inc. provides health information technology solutions. It offers 1-CDS (1-Click Decision Support), a clinical decision support system; and 1-Search, a search engine that provides evidence-based information for clinicians. The company was founded in 2012 and is based in Columbia, Missouri.

Edison Agrosciences

Pre Seed Round in 2016
Edison Agrosciences, Inc., an agricultural biotechnology company, develops biotechnological solutions for the development of plant-based industrial materials in United States. It primarily focuses on the development of alternative rubber crops for the manufacture of consumer, medical, and industrial products. The company was incorporated in 2013 and is based in Durham, North Carolina.

Kypha

Venture Round in 2018
Kypha Inc. discovers, develops, and commercializes in-vitro diagnostic biomarker tests within the inflammation and autoimmune space. It offers COMP ACT System, an inflammation and immune diagnostics to improve the way human health and disease activity is monitored and treated in patients. The company’s product is used in various applications across a range of indications that include lupus, stroke, traumatic brain injury, preeclampsia, infection, kidney disease, and transplant rejection. Kypha Inc. was formerly known as Kentucky Pharmaceuticals, Inc. The company was incorporated in 2009 and is based in St. Louis, Missouri.

Tansna Therapeutics

Seed Round in 2013
Tansna Therapeutics, Inc., a drug discovery and development company, develops and commercializes oral drugs to treat epilepsy. The company focuses on novel therapies for the treatment of central nervous system disorders. Its products under pipeline include oral anticonvulsant agent that reduces seizure frequency in patients with epilepsy. The company was founded in 2010 and is based in St. Louis, Missouri.

Euphrates Vascular

Series B in 2012
As of January 8, 2019, Pulse Therapeutics, Inc. was acquired by Ichor Vascular, Inc. Pulse Therapeutics, Inc., a medical technology company, develops magnetically-enhanced diffusion (MED) system for the treatment of stroke, heart, and other diseases. Its MED system is used to harness magnet-based technology to dissolve blood clots faster than current modalities. The company also provides MED MicroBeads that are designed to convey physician-selected agents faster to the blood clot; intravenously administered after thrombolysis therapy is initiated; and mechanical adjunct to standard of care IV thrombolysis. In addition, it offers touch screen operated MED Workstation. Pulse Therapeutics, Inc. was incorporated in 2008 and is based in St. Louis, Missouri.

NeuroLutions

Venture Round in 2015
Neurolutions Inc. develops brain-computer interface devices which enables the restoration of functions to the patients who are disabled due to neurological injury. The company was incorporated in 2007 and is based in St. Louis, Missouri.

APT Therapeutics

Seed Round in 2005
APT Therapeutics is a Biotechnology company located in 4041 Forest Park Ave., St. Louis, MO, United States.

Atomation

Private Placement in 2019
Atomation, founded in Tel Aviv and now with headquarters in Saint Louis, Missouri, is a business-to-business solutions company that uses an innovative Internet of Things (IoT) platform to connect existing, in-field, legacy objects and assets to the internet. Focused on making the data gathered by sensors into useful and actionable information, Atomation solves problems differently with affordable and simple solutions that allow businesses to transform operations and optimize their bottom line.

IN10T

Venture Round in 2023
IN10T Inc. provides designs and develops Internet based agronomic field research and data feeds platform. It provides agricultural field data analysis and farm field testing services. IN10T Inc. was founded in 2016 and is headquartered in Chesterfield, Missouri.

Peptyde Bio

Pre Seed Round in 2022
Peptyde Bio is an Agtech startup positioned to become the go-to supplier of new AMPs.

CuriMeta

Pre Seed Round in 2020
CuriMeta is a advanced real-world health data firm with a focus on life sciences. Driven by the belief that real-world health data maintained within systems of care have unique attributes not found elsewhere, CuriMeta augments, curates, and transforms data from our collaborating data contributors into secure, de-identified, aggregated datasets with high-explanatory power that can be compliantly exchanged with researchers to advance the science of medicine and develop lifesaving cures. With a commitment to full transparency, integrity, and accountability, CuriMeta utilizes a joint governance committee to review all data exchange requests from researchers, and adheres to highly stringent data security, patient privacy, and compliance standards as set forth by our collaborating data contributors, as well as regulatory authorities. By enabling and accelerating the exchange of real-world health data with the research community, our penultimate goal is to provide researchers the indispensable insights and evidence required to solve urgent scientific and clinical challenges and improve healthcare for all.

SanusEO

Pre Seed Round in 2015
SanusEO engagement and intervention platform trigger behavior modification at critical points in transition care saving healthcare dollars while improving patient outcomes. SanusEO is a mHealth company, offering mobile texting and web services to support population health management and help improve both clinical and financial outcomes. It was incorporated in 2012 and is based in St Louis, Missouri.