BioMedPartners

TOLREMO therapeutics AG is a biotechnology company based in Muttenz, Switzerland, that focuses on drug discovery and the development of therapies for cancer patients. Established in 2017, the company specializes in creating small molecules aimed at targeting novel pathways associated with drug resistance in cancer treatments. TOLREMO's innovative approach includes developing add-on therapies that enhance the effectiveness of existing oncogene-targeting drugs by dismantling the mechanisms that contribute to drug resistance. By eradicating cancer cells responsible for this resistance, TOLREMO aims to provide personalized anti-drug resistance therapies, ultimately improving patient response rates and prolonging the lives of those affected by cancer.

Alentis Therapeutics AG is a clinical-stage biopharmaceutical company based in Basel, Switzerland, focused on developing innovative therapies for advanced liver diseases, including liver fibrosis, cirrhosis, and liver cancer. Established in 2019, Alentis is recognized for its pioneering work in targeting CLDN1+ cancers through the use of anti-CLDN1 antibody-drug conjugates and other therapeutic modalities. The company's research platform incorporates clinically relevant read-outs and single-cell RNA sequencing of patient liver tissues, which aids in understanding and treating fibrotic diseases. Alentis aims to modify and reverse disease progression, ultimately addressing significant health challenges associated with liver-related conditions.

Noema Pharma AG is a biotechnology company based in Basel, Switzerland, founded in 2019. The company focuses on developing therapeutic products and therapies for orphan neurological disorders characterized by imbalanced neuronal networks. Its research and development efforts aim to address disabling symptoms in conditions affecting the nervous system, including Tuberous Sclerosis Complex, Trigeminal Neuralgia, and Tourette syndrome. By creating novel therapies, Noema Pharma seeks to improve the quality of life and patient outcomes for individuals suffering from these rare conditions.

TOLREMO therapeutics AG is a biotechnology company based in Muttenz, Switzerland, that focuses on drug discovery and the development of therapies for cancer patients. Established in 2017, the company specializes in creating small molecules aimed at targeting novel pathways associated with drug resistance in cancer treatments. TOLREMO's innovative approach includes developing add-on therapies that enhance the effectiveness of existing oncogene-targeting drugs by dismantling the mechanisms that contribute to drug resistance. By eradicating cancer cells responsible for this resistance, TOLREMO aims to provide personalized anti-drug resistance therapies, ultimately improving patient response rates and prolonging the lives of those affected by cancer.

Aleva Neurotherapeutics develops the next generations of implantable Deep Brain Stimulation systems, based on a MEMS technology. Our unique microfabricated devices enable Target Specific Stimulation and optimization of current therapies. They will also permit targeting new areas of the brain and the measurement of neurophysiological activity, translating into faster, more certain surgical placement of electrode leads. The first application will be in Deep Brain Stimulation for indications such as Parkinson's Disease and Essential Tremor. To maximize the value it can capture from its technology, Aleva intends to develop a series of two therapeutic products, while eliminating technological and clinical development risks at each stage. Our first product, directSTIM, an intelligent directional electrode connected to a best-in-class Deep Brain Stimulation system, has successfully completed an acute clinical trial at the Inselspital in Bern, Switzerland. It is currently further developped for a long term use. Aleva has been was founded in 2008 in Lausanne, Switzerland. It has raised 42 MUSD to date from prominent VCs, private investors and a strategic investor. The company is ISO13485 certified.

Alentis Therapeutics AG is a clinical-stage biopharmaceutical company based in Basel, Switzerland, focused on developing innovative therapies for advanced liver diseases, including liver fibrosis, cirrhosis, and liver cancer. Established in 2019, Alentis is recognized for its pioneering work in targeting CLDN1+ cancers through the use of anti-CLDN1 antibody-drug conjugates and other therapeutic modalities. The company's research platform incorporates clinically relevant read-outs and single-cell RNA sequencing of patient liver tissues, which aids in understanding and treating fibrotic diseases. Alentis aims to modify and reverse disease progression, ultimately addressing significant health challenges associated with liver-related conditions.

Amal Therapeutics SA is a biotechnology company based in Geneva, Switzerland, founded in 2012 as a spin-off from the University of Geneva. The company specializes in the research and development of therapeutic vaccines for oncology, utilizing a proprietary cell penetrating peptide platform. Amal Therapeutics focuses on creating peptide-based vaccines that generate cellular immune responses, including the activation of killer T cells that target tumor cells and promote long-lasting immunological memory. This approach aims to enhance the efficacy of cancer treatments and improve outcomes for patients. As of July 2019, Amal Therapeutics operates as a subsidiary of Boehringer Ingelheim GmbH.

TOLREMO therapeutics AG is a biotechnology company based in Muttenz, Switzerland, that focuses on drug discovery and the development of therapies for cancer patients. Established in 2017, the company specializes in creating small molecules aimed at targeting novel pathways associated with drug resistance in cancer treatments. TOLREMO's innovative approach includes developing add-on therapies that enhance the effectiveness of existing oncogene-targeting drugs by dismantling the mechanisms that contribute to drug resistance. By eradicating cancer cells responsible for this resistance, TOLREMO aims to provide personalized anti-drug resistance therapies, ultimately improving patient response rates and prolonging the lives of those affected by cancer.

Amal Therapeutics SA is a biotechnology company based in Geneva, Switzerland, founded in 2012 as a spin-off from the University of Geneva. The company specializes in the research and development of therapeutic vaccines for oncology, utilizing a proprietary cell penetrating peptide platform. Amal Therapeutics focuses on creating peptide-based vaccines that generate cellular immune responses, including the activation of killer T cells that target tumor cells and promote long-lasting immunological memory. This approach aims to enhance the efficacy of cancer treatments and improve outcomes for patients. As of July 2019, Amal Therapeutics operates as a subsidiary of Boehringer Ingelheim GmbH.

Aleva Neurotherapeutics develops the next generations of implantable Deep Brain Stimulation systems, based on a MEMS technology. Our unique microfabricated devices enable Target Specific Stimulation and optimization of current therapies. They will also permit targeting new areas of the brain and the measurement of neurophysiological activity, translating into faster, more certain surgical placement of electrode leads. The first application will be in Deep Brain Stimulation for indications such as Parkinson's Disease and Essential Tremor. To maximize the value it can capture from its technology, Aleva intends to develop a series of two therapeutic products, while eliminating technological and clinical development risks at each stage. Our first product, directSTIM, an intelligent directional electrode connected to a best-in-class Deep Brain Stimulation system, has successfully completed an acute clinical trial at the Inselspital in Bern, Switzerland. It is currently further developped for a long term use. Aleva has been was founded in 2008 in Lausanne, Switzerland. It has raised 42 MUSD to date from prominent VCs, private investors and a strategic investor. The company is ISO13485 certified.

Anergis is a clinical-stage biopharmaceutical company based in Lausanne, Switzerland, specializing in the discovery and development of allergy vaccines. Founded in 2001 by Francois Spertini, Anergis utilizes a proprietary technology known as Contiguous Overlapping Peptides to create vaccines designed for ultra-fast desensitization. The company focuses on developing immunotherapies that target common allergens, including birch pollen, ragweed pollen, and house dust mites. Anergis aims to provide patients with effective, long-term solutions for allergy relief, significantly improving treatment times.

Sequana Medical AG is a Swiss medical device company that specializes in developing implantable pump systems to manage fluid balance in the body. Its flagship product, the alfapump, is designed to continuously remove ascites, a condition characterized by fluid accumulation in the abdominal cavity, commonly seen in patients with advanced liver disease, certain cancers, or congestive heart failure. The alfapump is notable for being the first automated system that facilitates the natural expulsion of excess fluid through urination. In addition to treating ascites, the company's pump technology has potential applications in managing pleural effusions and fluid overload in patients with end-stage renal disease and heart failure. Founded in 2002 and headquartered in Zurich, Switzerland, Sequana Medical has expanded its reach to various markets, with a significant portion of its revenue generated in Germany.

Anergis is a clinical-stage biopharmaceutical company based in Lausanne, Switzerland, specializing in the discovery and development of allergy vaccines. Founded in 2001 by Francois Spertini, Anergis utilizes a proprietary technology known as Contiguous Overlapping Peptides to create vaccines designed for ultra-fast desensitization. The company focuses on developing immunotherapies that target common allergens, including birch pollen, ragweed pollen, and house dust mites. Anergis aims to provide patients with effective, long-term solutions for allergy relief, significantly improving treatment times.

Sequana Medical AG is a Swiss medical device company that specializes in developing implantable pump systems to manage fluid balance in the body. Its flagship product, the alfapump, is designed to continuously remove ascites, a condition characterized by fluid accumulation in the abdominal cavity, commonly seen in patients with advanced liver disease, certain cancers, or congestive heart failure. The alfapump is notable for being the first automated system that facilitates the natural expulsion of excess fluid through urination. In addition to treating ascites, the company's pump technology has potential applications in managing pleural effusions and fluid overload in patients with end-stage renal disease and heart failure. Founded in 2002 and headquartered in Zurich, Switzerland, Sequana Medical has expanded its reach to various markets, with a significant portion of its revenue generated in Germany.

Anergis is a clinical-stage biopharmaceutical company based in Lausanne, Switzerland, specializing in the discovery and development of allergy vaccines. Founded in 2001 by Francois Spertini, Anergis utilizes a proprietary technology known as Contiguous Overlapping Peptides to create vaccines designed for ultra-fast desensitization. The company focuses on developing immunotherapies that target common allergens, including birch pollen, ragweed pollen, and house dust mites. Anergis aims to provide patients with effective, long-term solutions for allergy relief, significantly improving treatment times.

Delenex Therapeutics AG is a Swiss biotech company developing therapeutic antibody fragments targeting serious medical diseases with high unmet need. The company's fragments are being designed for local/topical application by using the benefits of an antibody therapy with only limited systemic exposure. Its clinically validated technology delivers antibodies exhibiting the highest affinity, solubility and stability all combined with a very low risk of immunogenicity.

Spinelab, based in Winterthur, Switzerland, is a privately held company dedicated entirely to the development of a new generation of spinal motion preservation devices. Spinelab Ltd. is the manufacturer and distributor of the CE-marked implant and instrument system Elaspine™ for the treatment of degenerative lumbar spine disease.

Aleva Neurotherapeutics develops the next generations of implantable Deep Brain Stimulation systems, based on a MEMS technology. Our unique microfabricated devices enable Target Specific Stimulation and optimization of current therapies. They will also permit targeting new areas of the brain and the measurement of neurophysiological activity, translating into faster, more certain surgical placement of electrode leads. The first application will be in Deep Brain Stimulation for indications such as Parkinson's Disease and Essential Tremor. To maximize the value it can capture from its technology, Aleva intends to develop a series of two therapeutic products, while eliminating technological and clinical development risks at each stage. Our first product, directSTIM, an intelligent directional electrode connected to a best-in-class Deep Brain Stimulation system, has successfully completed an acute clinical trial at the Inselspital in Bern, Switzerland. It is currently further developped for a long term use. Aleva has been was founded in 2008 in Lausanne, Switzerland. It has raised 42 MUSD to date from prominent VCs, private investors and a strategic investor. The company is ISO13485 certified.

Aleva Neurotherapeutics develops the next generations of implantable Deep Brain Stimulation systems, based on a MEMS technology. Our unique microfabricated devices enable Target Specific Stimulation and optimization of current therapies. They will also permit targeting new areas of the brain and the measurement of neurophysiological activity, translating into faster, more certain surgical placement of electrode leads. The first application will be in Deep Brain Stimulation for indications such as Parkinson's Disease and Essential Tremor. To maximize the value it can capture from its technology, Aleva intends to develop a series of two therapeutic products, while eliminating technological and clinical development risks at each stage. Our first product, directSTIM, an intelligent directional electrode connected to a best-in-class Deep Brain Stimulation system, has successfully completed an acute clinical trial at the Inselspital in Bern, Switzerland. It is currently further developped for a long term use. Aleva has been was founded in 2008 in Lausanne, Switzerland. It has raised 42 MUSD to date from prominent VCs, private investors and a strategic investor. The company is ISO13485 certified.

Delenex Therapeutics AG is a Swiss biotech company developing therapeutic antibody fragments targeting serious medical diseases with high unmet need. The company's fragments are being designed for local/topical application by using the benefits of an antibody therapy with only limited systemic exposure. Its clinically validated technology delivers antibodies exhibiting the highest affinity, solubility and stability all combined with a very low risk of immunogenicity.

Anergis is a clinical-stage biopharmaceutical company based in Lausanne, Switzerland, specializing in the discovery and development of allergy vaccines. Founded in 2001 by Francois Spertini, Anergis utilizes a proprietary technology known as Contiguous Overlapping Peptides to create vaccines designed for ultra-fast desensitization. The company focuses on developing immunotherapies that target common allergens, including birch pollen, ragweed pollen, and house dust mites. Anergis aims to provide patients with effective, long-term solutions for allergy relief, significantly improving treatment times.

Sequana Medical AG is a Swiss medical device company that specializes in developing implantable pump systems to manage fluid balance in the body. Its flagship product, the alfapump, is designed to continuously remove ascites, a condition characterized by fluid accumulation in the abdominal cavity, commonly seen in patients with advanced liver disease, certain cancers, or congestive heart failure. The alfapump is notable for being the first automated system that facilitates the natural expulsion of excess fluid through urination. In addition to treating ascites, the company's pump technology has potential applications in managing pleural effusions and fluid overload in patients with end-stage renal disease and heart failure. Founded in 2002 and headquartered in Zurich, Switzerland, Sequana Medical has expanded its reach to various markets, with a significant portion of its revenue generated in Germany.

Delenex Therapeutics AG is a Swiss biotech company developing therapeutic antibody fragments targeting serious medical diseases with high unmet need. The company's fragments are being designed for local/topical application by using the benefits of an antibody therapy with only limited systemic exposure. Its clinically validated technology delivers antibodies exhibiting the highest affinity, solubility and stability all combined with a very low risk of immunogenicity.

Evolva is a biotechnology company based in Reinach, Switzerland, founded in 2004. The company specializes in the research, development, and commercialization of nature-based ingredients that are ready for formulation. Utilizing a proprietary synthetic biology platform, Evolva creates innovative small-molecule compounds that replicate the beneficial properties of natural products while mitigating their disadvantages. Their offerings find applications in various sectors, including flavors and fragrances, health ingredients, and health protection. Through its advanced technology, Evolva aims to provide high-quality ingredients that meet the needs of diverse industries.

Evolva is a biotechnology company based in Reinach, Switzerland, founded in 2004. The company specializes in the research, development, and commercialization of nature-based ingredients that are ready for formulation. Utilizing a proprietary synthetic biology platform, Evolva creates innovative small-molecule compounds that replicate the beneficial properties of natural products while mitigating their disadvantages. Their offerings find applications in various sectors, including flavors and fragrances, health ingredients, and health protection. Through its advanced technology, Evolva aims to provide high-quality ingredients that meet the needs of diverse industries.

Spinelab, based in Winterthur, Switzerland, is a privately held company dedicated entirely to the development of a new generation of spinal motion preservation devices. Spinelab Ltd. is the manufacturer and distributor of the CE-marked implant and instrument system Elaspine™ for the treatment of degenerative lumbar spine disease.

Lumavita is an independent, specialty biopharmaceutical company focused on global development and commercialisation of novel anti-infectives for women’s health. Lumavita is based in Basel, Switzerland, home to a significant and growing biopharmaceutical sector.

Idiag is a specialist in interfacing research & development with sales and marketing. A central business aim is to convert innovative ideas on medical technology into products ready to market. Therefore Idiag offers to Universities and Innovation Centres, to take over final development, production and marketing for their unused medical product potential. Furthermore Idiag offers to manufacturer of high quality supplementing products, to act as reseller. Idiag then uses its existing resources, networks and excellence for market penetration and sales, within Switzerland and Germany.

Spinelab, based in Winterthur, Switzerland, is a privately held company dedicated entirely to the development of a new generation of spinal motion preservation devices. Spinelab Ltd. is the manufacturer and distributor of the CE-marked implant and instrument system Elaspine™ for the treatment of degenerative lumbar spine disease.

Okairos AG, a bio-pharmaceutical company, focuses on the discovery and development of genetic T-cell vaccines, including hepatitis C virus. The company also provides health and allied services. It has operations in Rome and Naples, Italy. The company is based in Basel, Switzerland. Okairos AG was former subsidiary of Istituto Di Ricerche Di Biologia Molecolare P. Angeletti Spa.

Santhera Pharmaceuticals is a Swiss specialty pharmaceutical company dedicated to developing and marketing innovative treatments for mitochondrial and neuromuscular diseases. These conditions represent areas of high unmet medical need, often involving orphan and niche indications that currently lack effective therapies. The company focuses on various therapeutic segments, including neuro-ophthalmological, pulmonary, and neuromuscular diseases. Santhera primarily generates its revenue from the European Union, aiming to address significant health challenges faced by patients with these rare disorders.

Symetis is a Swiss Company developing innovative minimally invasive heart valve replacement therapies for patients suffering from heart valve diseases. Symetis is dedicated to improving patient care and safety by offering simple, accurate solutions for heart valve replacement. Its proprietary Acurateâ„¢Aortic Valve Replacement System features a unique self-positioning design providing facile implant positioning and alignment as well as unrivalled ease of use.

4-Antibody AG is a biopharmaceutical company based in Basel, Switzerland, specializing in the development of antibody therapeutics with a focus on immuno-oncology. Founded in 2002, the company utilizes its proprietary Retrocyte Display technology platform to generate therapeutic antibody drug candidates from human antibody libraries expressed in mammalian B-lineage lymphocytes. In addition to providing its technology to pharmaceutical partners, 4-Antibody AG is actively developing a pipeline of preclinical checkpoint antibody programs targeting various immune checkpoints, including GITR, OX40, CTLA-4, PD-1, TIM-3, and LAG-3.