Bioqube Ventures NV is a venture capital firm based in Brussels, Belgium, established in 2016. The company specializes in early-stage investments in the life sciences sector, particularly targeting European biotech companies that are developing innovative therapeutic assets and technologies. Bioqube Ventures focuses on investments in the Benelux countries, France, and Germany, aiming to advance scientific innovation and support companies with medicines in the testing phase. The firm employs a dual investment model that includes traditional early investment rounds and special attention to projects that require additional de-risking before launching new ventures. With a diverse team of fund managers, sector experts, and serial entrepreneurs, Bioqube Ventures takes a hands-on approach to drive growth and maximize value for its portfolio companies and investors.
Commit Biologics is a biotechnology research company based in Aarhus, Denmark, founded in 2021. The company focuses on developing a novel immunotherapy platform designed for the treatment of various cancers. This platform utilizes b-specific domain antibodies, which are engineered to effectively target and kill tumor cells. The technology is modular, allowing for customization to engage the body's innate immune response. By activating the complement component of the immune system, Commit Biologics aims to provide innovative treatment options for both cancer and autoimmune diseases.
SynOx Therapeutics
Series B in 2024
SynOx Therapeutics is a clinical-stage biopharmaceutical company based in Dublin, Ireland, that specializes in the development of innovative therapies for cancer. The company's primary focus is on emactuzumab, a humanized monoclonal antibody targeting CSF-1R, aimed at depleting macrophages within tumor tissues. This therapy is being investigated for its potential in treating diffuse tenosynovial giant cell tumors and other macrophage-mediated diseases. Established in 2019, SynOx Therapeutics is backed by experienced investors in the biopharmaceutical field, emphasizing its commitment to addressing the unmet clinical needs of patients and improving their quality of life through advanced treatment options.
Catalym
Series D in 2024
CatalYm GmbH, founded in 2016 and based in Munich, Germany, is a biotechnology company focused on developing innovative immunotherapies for cancer patients. The company has identified GDF-15 as a key regulator of the immune system within the tumor microenvironment. By neutralizing GDF-15, CatalYm aims to enhance the immune response against solid tumors, potentially leading to meaningful clinical outcomes. Its CTL-002 program is designed to demonstrate clinical proof-of-concept across multiple solid tumor indications, offering the prospect of expanding treatment options for cancer patients. Through its approach, CatalYm seeks to transform the tumor microenvironment, making tumors more accessible to the immune system and improving both survival rates and quality of life for patients.
Commit Biologics
Seed Round in 2024
Commit Biologics is a biotechnology research company based in Aarhus, Denmark, founded in 2021. The company focuses on developing a novel immunotherapy platform designed for the treatment of various cancers. This platform utilizes b-specific domain antibodies, which are engineered to effectively target and kill tumor cells. The technology is modular, allowing for customization to engage the body's innate immune response. By activating the complement component of the immune system, Commit Biologics aims to provide innovative treatment options for both cancer and autoimmune diseases.
SynOx Therapeutics
Series B in 2024
SynOx Therapeutics is a clinical-stage biopharmaceutical company based in Dublin, Ireland, that specializes in the development of innovative therapies for cancer. The company's primary focus is on emactuzumab, a humanized monoclonal antibody targeting CSF-1R, aimed at depleting macrophages within tumor tissues. This therapy is being investigated for its potential in treating diffuse tenosynovial giant cell tumors and other macrophage-mediated diseases. Established in 2019, SynOx Therapeutics is backed by experienced investors in the biopharmaceutical field, emphasizing its commitment to addressing the unmet clinical needs of patients and improving their quality of life through advanced treatment options.
Anavo Therapeutics
Seed Round in 2023
Anavo Therapeutics is pioneering the systematic drugging of phosphatases, a target area that has long been deemed undruggable. The company focuses on developing first-in-class therapeutic programs, particularly in oncology, leveraging its expertise in phosphatase-driven disease biology and drug discovery. Anavo aims to create a diverse pipeline of therapeutics across various indications by fostering strategic partnerships and collaborations. Through this innovative approach, Anavo seeks to unlock the potential of phosphatase-targeted allosteric modulators, advancing the field of targeted therapies in medicine.
Enhanc3D Genomics
Series A in 2022
Enhanc3D Genomics is a functional genomics company that focuses on understanding the three-dimensional organization of DNA and its implications for health and disease. The company has developed the GenLink3D platform, which facilitates the analysis of genetic variations and gene function by providing high-resolution profiles of genome folding. This technology allows researchers to examine the effects of mutations on distant genes and their roles in disease progression. By offering insights into gene interactions and enhancer activity, Enhanc3D Genomics aims to support the advancement of novel drug development in areas with significant unmet medical needs.
Tridek-One
Venture Round in 2022
Tridek-One is a biotechnology company focused on developing immunomodulatory products aimed at treating autoimmune diseases and inflammatory disorders. The company has created a peptide that preserves a cluster of truncated CD31 molecules at the membrane, allowing for the moderation of overactive immune responses without complete blockade. This innovative approach enables medical companies to provide enhanced therapeutic options, ultimately improving patient outcomes and quality of life.
Egle Therapeutics
Series A in 2021
Egle Therapeutics SAS is a biotechnology company based in Paris, France, founded in 2020. It specializes in developing innovative immunotherapies that target immune suppressor regulatory T-cells (Tregs) for the treatment of oncology and autoimmune diseases. The company's research focuses on a proprietary drug pipeline that includes computationally designed IL-2 variants aimed at modulating Treg activity. This approach seeks to either engage or dis-engage Tregs, facilitating the development of therapies that can effectively combat cancer and other related conditions by addressing the immune suppression caused by Tregs. Egle Therapeutics aims to advance its unique portfolio to provide new treatment options in the healthcare field.
Anavo Therapeutics
Seed Round in 2021
Anavo Therapeutics is pioneering the systematic drugging of phosphatases, a target area that has long been deemed undruggable. The company focuses on developing first-in-class therapeutic programs, particularly in oncology, leveraging its expertise in phosphatase-driven disease biology and drug discovery. Anavo aims to create a diverse pipeline of therapeutics across various indications by fostering strategic partnerships and collaborations. Through this innovative approach, Anavo seeks to unlock the potential of phosphatase-targeted allosteric modulators, advancing the field of targeted therapies in medicine.
Primmune Therapeutics
Series A in 2021
Primmune Therapeutics, Inc. is a biotechnology company based in San Diego, California, focused on developing small molecule, orally administered toll-like receptor 7 (TLR7) agonists for cancer immunotherapy. Founded in 2017, the company aims to stimulate innate immunity to enhance the effectiveness of adaptive cancer treatments, such as checkpoint inhibitors. Its TLR7 agonist is designed to activate the immune system by producing cytokines and chemokines that boost cellular responses and facilitate the activation of natural killer cells. This approach enables healthcare providers to target metastatic diseases more effectively and promotes B-cell proliferation and activation, ultimately improving overall response rates and treatment durability for patients.
Enhanc3D Genomics
Seed Round in 2021
Enhanc3D Genomics is a functional genomics company that focuses on understanding the three-dimensional organization of DNA and its implications for health and disease. The company has developed the GenLink3D platform, which facilitates the analysis of genetic variations and gene function by providing high-resolution profiles of genome folding. This technology allows researchers to examine the effects of mutations on distant genes and their roles in disease progression. By offering insights into gene interactions and enhancer activity, Enhanc3D Genomics aims to support the advancement of novel drug development in areas with significant unmet medical needs.
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