Bioqube Ventures

Bioqube Ventures NV is a venture capital firm based in Brussels, Belgium, established in 2016. The company specializes in early-stage investments in the life sciences sector, particularly targeting European biotech companies that are developing innovative therapeutic assets and technologies. Bioqube Ventures focuses on investments in the Benelux countries, France, and Germany, aiming to advance scientific innovation and support companies with medicines in the testing phase. The firm employs a dual investment model that includes traditional early investment rounds and special attention to projects that require additional de-risking before launching new ventures. With a diverse team of fund managers, sector experts, and serial entrepreneurs, Bioqube Ventures takes a hands-on approach to drive growth and maximize value for its portfolio companies and investors.

Alexander Demoulin

Associate

Debora Dumont

Managing Partner

Jacques Mizrahi

Venture Partner

Dirk Reyn

Managing Partner

Clement Salque

Analyst

Tol Trimborn

Venture Partner

Joris Vanderlocht

Chief Scientific Director

Nico Vandervelpen

Managing Partner

Roderick Verhelst

Principal

13 past transactions

Commit Biologics

Seed Round in 2025
Founded in 2021, Commit Biologics is a Danish biotechnology company dedicated to developing innovative immunotherapy platforms for cancer treatment. Its proprietary platform employs b-specific domain antibodies to engage the body's innate immune response, targeting and destroying cancer cells.

SynOx Therapeutics

Series B in 2024
SynOx Therapeutics is a biopharmaceutical company focused on developing emactuzumab, a monoclonal antibody targeting CSF-1R, for treating diffuse tenosynovial giant cell tumors and other macrophage-mediated diseases. Incorporated in 2019, the company is based in Dublin, Ireland.

Catalym

Series D in 2024
Catalym GmbH, established in Munich, Germany in 2016, is a biotechnology company dedicated to developing innovative immunotherapies for cancer patients. The company focuses on neutralizing GDF-15, a central regulator of the immune system in the tumor microenvironment, aiming to demonstrate clinical proof-of-concept across multiple solid tumor indications with its lead program CTL-002. Catalym's mission is to transform cancer patients' lives by engaging their own immune systems and improving treatment options.

Commit Biologics

Seed Round in 2024
Founded in 2021, Commit Biologics is a Danish biotechnology company dedicated to developing innovative immunotherapy platforms for cancer treatment. Its proprietary platform employs b-specific domain antibodies to engage the body's innate immune response, targeting and destroying cancer cells.

SynOx Therapeutics

Series B in 2024
SynOx Therapeutics is a biopharmaceutical company focused on developing emactuzumab, a monoclonal antibody targeting CSF-1R, for treating diffuse tenosynovial giant cell tumors and other macrophage-mediated diseases. Incorporated in 2019, the company is based in Dublin, Ireland.

Anavo Therapeutics

Seed Round in 2023
Anavo Therapeutics is a biotechnology company focused on systematically drugging phosphatases, a historically undruggable target space. The company applies a platform that combines phosphatase biology with drug discovery to develop first-in-class, phosphatase-targeted therapies, including allosteric modulators. In oncology, Anavo is pursuing multiple proprietary programs and aims to build a robust pipeline across several indications. The organization also seeks partnerships to advance its platform and attract scientific expertise in phosphatase-driven disease biology, enabling the development of therapies that modulate phosphatase activity to address unmet medical needs.

Enhanc3D Genomics

Series A in 2022
Enhanc3D Genomics is a functional genomics company focused on the three-dimensional organization of DNA in health and disease. Its GenLink3D platform analyzes how genetic mutations impact distant genes, revealing their influence on disease progression, and it supports large-scale analysis of genetic variation and gene function through high-resolution profiling of 3D genome folding for all genes and their enhancers, enabling researchers to advance novel drugs for areas of unmet medical need.

Tridek-One

Venture Round in 2022
Tridek-One is a biotechnology company focused on developing immunomodulatory products aimed at addressing auto-immune and inflammatory disorders. The company's primary product is a peptide designed to maintain a cluster of truncated CD31 molecules at the membrane, which helps moderate overactive immune responses without complete blockade. By facilitating improved treatment options for medical companies, Tridek-One seeks to enhance the quality of life for patients suffering from these conditions.

Egle Therapeutics

Series A in 2021
Founded in 2020, Egle Therapeutics is a biotechnology company based in Paris, France. It specializes in developing immunotherapies targeting immune suppressor regulatory T-cells (Tregs) for oncology and autoimmune diseases.

Anavo Therapeutics

Seed Round in 2021
Anavo Therapeutics is a biotechnology company focused on systematically drugging phosphatases, a historically undruggable target space. The company applies a platform that combines phosphatase biology with drug discovery to develop first-in-class, phosphatase-targeted therapies, including allosteric modulators. In oncology, Anavo is pursuing multiple proprietary programs and aims to build a robust pipeline across several indications. The organization also seeks partnerships to advance its platform and attract scientific expertise in phosphatase-driven disease biology, enabling the development of therapies that modulate phosphatase activity to address unmet medical needs.

Primmune Therapeutics

Series A in 2021
Primmune Therapeutics is a biotechnology company developing orally administered small molecule toll-like receptor 7 (TLR7) agonists to stimulate innate immunity in cancer immunotherapy. The TLR7 agonists aim to activate systemic innate immune responses, promoting cytokine and chemokine production, NK cell activation, and B-cell proliferation to support anti-tumor activity. The company intends to combine these agents with adaptive cancer therapies such as checkpoint inhibitors to improve response rates and durability, and targets metastatic cancers.

Enhanc3D Genomics

Seed Round in 2021
Enhanc3D Genomics is a functional genomics company focused on the three-dimensional organization of DNA in health and disease. Its GenLink3D platform analyzes how genetic mutations impact distant genes, revealing their influence on disease progression, and it supports large-scale analysis of genetic variation and gene function through high-resolution profiling of 3D genome folding for all genes and their enhancers, enabling researchers to advance novel drugs for areas of unmet medical need.
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