Bioverge Ventures

EnClear Therapies, Inc. is a life sciences company based in Newburyport, Massachusetts, that specializes in developing device-based therapies for neurodegenerative diseases. The company focuses on the delivery and monitoring of cerebrospinal fluid (CSF) and employs a proprietary therapeutic platform designed to remove toxic proteins from the CSF. EnClear's initial products are aimed at enhancing the quality of life for patients suffering from conditions such as Amyotrophic Lateral Sclerosis (ALS) and Progressive Supranuclear Palsy (PSP). Incorporated in 2018, EnClear Therapies is dedicated to advancing treatments that can halt disease progression and extend patient lives.

UberDoc, established in 2016 and based in Boston, is a digital platform that facilitates direct access to medical specialists for patients seeking urgent care. The company offers a transparent pricing structure, allowing patients to connect with qualified doctors without the need for referrals or insurance paperwork. By leveraging advanced mobile technology, UberDoc simplifies the appointment process, enabling users to search for specialists, book appointments, and pay using various methods including Health Savings Accounts and credit cards. A nominal transaction fee is charged to secure appointments, with additional fees applicable post-consultation. Founded by Paula Muto, a recognized vascular and general surgeon, UberDoc has rapidly expanded its reach, enrolling thousands of doctors across the United States and serving patients daily. The platform has earned a reputation as a leader in the digital health community, participating in numerous industry conferences.

My Diabetes Tutor is a provider of diabetes education telehealth services, recently recognized as the first accredited diabetes education telehealth program in California by the American Association of Diabetes Educators. The company focuses on delivering high-quality diabetes education to individuals with type 1, type 2, and gestational diabetes, as well as those with pre-diabetes. By emphasizing preventative medicine and health promotion, My Diabetes Tutor aims to empower patients at risk for diabetes with the knowledge and skills necessary for effective self-management of the disease and its related conditions. The company has also contributed to the field through scientific presentations, including participation in the American Diabetes Association Scientific Meeting, further solidifying its commitment to advancing diabetes education.

Modulo Bio simulates the neuroimmune system to find medication candidates that target microglia cells. The organization's proprietary neuroimmune platform combines the most recent developments in stem cell biology and neuroscience with software, automation, and artificial intelligence to create novel treatments.

JelikaLite is a medical device company focused on developing innovative solutions for children with autism spectrum disorders. The company specializes in creating wearable therapeutic devices that utilize non-invasive methods to enhance pediatric neurological health. Their technology integrates infrared light, EEG sensors, and an AI personalization platform to provide targeted brain stimulation. By employing these advanced techniques, JelikaLite aims to alleviate autism symptoms, improving children's speech, reducing anxiety, and enhancing overall responsiveness. The company's commitment to promoting brain health through innovative, non-invasive therapies sets it apart in the healthcare sector.

Eigen Therapeutics is a biotechnology company dedicated to advancing cancer treatment through the development of innovative therapies. It specializes in "priming" therapies that enhance the effectiveness of targeted treatments by addressing cancer heterogeneity, which makes cancer cells more susceptible to therapeutic interventions while simultaneously protecting healthy cells. Eigen is creating a high-throughput discovery platform that integrates proprietary machine learning algorithms to identify novel drug classes and therapeutic approaches capable of altering a cell’s state to increase vulnerability to treatments. This platform combines biology and engineering, utilizing in-house developed robotic systems, laboratory operations software, and machine learning analysis pipelines. The company's mission focuses on improving patient outcomes by providing novel combination therapeutics that enhance efficacy and reduce toxicity in cancer care, ultimately aiming to meet significant medical needs in oncology.

GigaMune, established in 2017 as a spin-out from GigaGen, focuses on advancing cancer treatment through innovative T cell therapies. The company leverages its deep understanding of T cell responses to tumors, combining this expertise with a groundbreaking approach to T cell receptor (TCR) discovery. GigaMune's technology facilitates the identification of anti-tumor payloads through database-scale sequence searches and high-throughput screening, as well as the development of novel viral vectors for payload delivery. By integrating these capabilities, GigaMune aims to provide healthcare professionals with effective therapeutic options for cancer treatment.

Notable Labs, Inc. is a clinical-stage company that specializes in personalized lab testing services for cancer patients, particularly those with brain cancer. Founded in 2014 and based in Foster City, California, the company utilizes its proprietary Predictive Precision Medicines Platform to conduct drug combination experiments on patients' tumors. This platform allows Notable Labs to simulate cancer treatments and predict patient responses to specific therapies, enabling healthcare providers to prioritize combinations of FDA-approved treatments that can be prescribed without the need for clinical trials. By providing detailed reports to physicians, Notable Labs aims to enhance treatment efficacy and expedite therapeutic development for patients.

Foresight Mental Health is a technology-driven provider of psychiatry and therapy services, operating a network of clinics dedicated to mental health and wellness. The company employs a diverse team that includes psychiatrists, therapists, and psychiatric nurse practitioners who deliver care directly to patients. Foresight enhances its treatment offerings through innovative technology developed in collaboration with software and biomedical engineers, aimed at transforming the mental healthcare experience. By utilizing comprehensive patient profiles and a database of scientific research, the company conducts detailed analyses that include genetic profiles and assessments of brain-chemical balance. This holistic approach enables Foresight to offer tailored treatments, ultimately helping patients achieve improved mental health and overall well-being.

Octant Bio is a company focused on developing synthetic technology to enhance health and treat diseases. The firm employs synthetic biology, genome engineering, next-generation sequencing, and computational tools to measure the activity of thousands of receptor pathways in human cells simultaneously. This approach allows scientists to use machine learning methods to engineer small molecules that can interact with multiple receptors, offering new potential for treating complex diseases.

Alto Neuroscience is a clinical-stage biopharmaceutical company focused on redefining psychiatry through the integration of patient neurobiology into the drug development process. Utilizing an AI-enabled biomarker platform, the company combines diverse information about patients' brain activity and behavior to create personalized and effective treatment options. Alto Neuroscience is developing several clinical assets, including ALTO-100, ALTO-202, ALTO-101, and ALTO-300, primarily targeting depressive disorders and schizophrenia, identified through independent brain-based biomarkers. By moving away from traditional trial-and-error methods, the company aims to align its innovative therapies with the specific needs of patients, ultimately improving the management of mental health conditions.

Bionaut Labs, established in 2016 and based in Palo Alto, California, specializes in the design, manufacture, and control of intra-tissue navigation platforms. The company's core technology involves nano/micro robots, dubbed 'Bionauts', which operate within the body to deliver treatments with anatomical precision. Bionaut Labs aims to revolutionize the treatment of central nervous system disorders by enabling new therapeutic technologies like gene therapy and CRISPR-Cas9 in challenging clinical settings. Their remote-controlled micro-robots allow for precise targeting, tracking, and payload release, potentially automating complex surgeries remotely without external incisions.

Eigen Therapeutics is a biotechnology company dedicated to advancing cancer treatment through the development of innovative therapies. It specializes in "priming" therapies that enhance the effectiveness of targeted treatments by addressing cancer heterogeneity, which makes cancer cells more susceptible to therapeutic interventions while simultaneously protecting healthy cells. Eigen is creating a high-throughput discovery platform that integrates proprietary machine learning algorithms to identify novel drug classes and therapeutic approaches capable of altering a cell’s state to increase vulnerability to treatments. This platform combines biology and engineering, utilizing in-house developed robotic systems, laboratory operations software, and machine learning analysis pipelines. The company's mission focuses on improving patient outcomes by providing novel combination therapeutics that enhance efficacy and reduce toxicity in cancer care, ultimately aiming to meet significant medical needs in oncology.

Circularis Biotechnologies, Inc. is a biotechnology company founded in 2014 and headquartered in Oakland, California. The company specializes in developing innovative methods to regulate gene expression, which enhances the production yields of biotherapeutics. Circularis offers a range of products, including RACRE Variant Libraries, hCMV Variant Library, Protein expression with CMV promoters, and T7 Variant Library. In addition, it provides various services such as RACRE Enhancement, RACRE Discovery, RACRE Technology Access Program, and Ribozyme Analysis of Cis-Regulatory Elements. Through its advanced technologies and services, Circularis aims to improve the efficiency and effectiveness of biotherapeutic production.

Ochre Bio Ltd is a biotechnology company focused on developing genomic medicines specifically for transplanted livers and the treatment of fatty liver conditions. Founded in 2019 and based in Headington, United Kingdom, the company employs advanced genomic techniques to identify and inhibit overactive genes associated with liver diseases. This approach includes testing therapies in discarded donor livers that are maintained outside the body, ensuring that potential treatments can be evaluated in a relevant biological context. With over 15 years of expertise in liver genomics research, Ochre Bio aims to create a pipeline of innovative medicines that address liver and liver-mediated conditions, ultimately enhancing the availability of healthy livers for transplantation and reducing complications associated with cirrhosis. The company operates within Oxford's biotechnology innovation hub, leveraging its scientific foundation to advance therapeutic solutions in the field of liver health.

NutriSense, established in 2019 and headquartered in Chicago, Illinois, specializes in AI-driven corporate wellness programs. The company offers a comprehensive solution comprising continuous glucose monitoring (CGM) devices, a tracking app for diet management, and personalized consultations with registered dietitians. NutriSense leverages machine learning technology to provide real-time blood glucose level monitoring and tailored nutrition insights, aiming to empower individuals to achieve their health goals.

BioROSA Technologies Inc. is a biotechnology company focused on developing diagnostic tools for Autism Spectrum Disorders (ASD). Founded in 2018 and headquartered in Belmont, Massachusetts, the company specializes in creating biologically-based blood tests that assist clinicians in identifying individuals at risk for ASD. By utilizing machine learning to analyze biological data, BioROSA Technologies aims to provide reliable and accurate diagnoses, facilitating early detection and timely treatment. Additionally, the company's technology supports therapeutic trials by evaluating pharmacodynamics and patient stratification, thereby enhancing the overall standard of care for ASD.

Juno Diagnostics, Inc. is a health technology company based in San Diego, California, founded in 2017. The company specializes in developing cell-free DNA-based noninvasive prenatal testing, providing women and their healthcare providers with crucial genetic information. Juno Diagnostics aims to democratize access to high-value genetic data by creating simple and cost-effective testing devices that facilitate point-of-need genetic testing. Their innovative technology enhances sample collection and delivers high-quality test results without the need for traditional phlebotomy procedures, thus reducing costs and lead times associated with genetic testing. Additionally, Juno is involved in the development of genetic testing tools for applications in epigenetics, inherited diseases, and cancer diagnostics.

HepaTx Corporation, founded in 2015 and headquartered in Palo Alto, California, specializes in developing regenerative medicine solutions for liver diseases. The company focuses on creating innovative therapies that address the urgent need for improved treatments for life-threatening liver conditions. Utilizing technology developed at Stanford University, HepaTx efficiently produces hepatocytes for therapeutic applications, aiming to replace lost liver function in patients with end-stage liver disease. This approach has the potential to reduce the need for costly and complex whole organ transplants, offering a novel and cost-effective alternative for patients previously deemed untreatable.

Juno Diagnostics, Inc. is a health technology company based in San Diego, California, founded in 2017. The company specializes in developing cell-free DNA-based noninvasive prenatal testing, providing women and their healthcare providers with crucial genetic information. Juno Diagnostics aims to democratize access to high-value genetic data by creating simple and cost-effective testing devices that facilitate point-of-need genetic testing. Their innovative technology enhances sample collection and delivers high-quality test results without the need for traditional phlebotomy procedures, thus reducing costs and lead times associated with genetic testing. Additionally, Juno is involved in the development of genetic testing tools for applications in epigenetics, inherited diseases, and cancer diagnostics.

Elucid is a Boston-based biotechnology and medical technology company dedicated to enhancing cardiovascular diagnostic imaging through machine learning. The company has developed ElucidVivo, the first FDA-cleared software that evaluates plaque vulnerability from a single computed tomography angiography scan, aiding in the assessment of heart attack and stroke risks as well as informing treatment decisions. Elucid's technology enables objective quantification of arterial plaque extent and stability, providing a cost-effective and non-invasive means of capturing essential patient health information. In addition to its proprietary software, Elucid collaborates with pharmaceutical companies, healthcare providers, and research organizations to offer quantitative image analysis services, ultimately aiming to improve patient outcomes in cardiovascular care.

IVIVA Medical, Inc. is a biotechnology company based in Beverly, Massachusetts, focused on developing innovative therapies for end-stage renal disease (ESRD). Founded in 2013, the company aims to address the critical shortage of donor organs by creating autologous tissue constructs that provide alternative treatments for patients suffering from this condition, which affects over 500,000 individuals in the United States. IVIVA Medical leverages advanced technologies in tissue engineering, 3D additive manufacturing, and stem cell biology to create bioartificial platforms and systems. These platforms not only facilitate therapeutic applications but also serve as essential building blocks for the next generation of engineered, functionalized tissues, positioning IVIVA Medical at the forefront of regenerative medicine and enhancing the capacity of medical professionals to manage end-stage kidney disease.

Ancilia Biosciences is a biotechnology company focused on developing engineered bacterial therapies aimed at treating diseases associated with the microbiome. The company specializes in creating virus-resistant live bacterial products that modulate the human microbiome, specifically targeting the viral components of the gut microbiome. By concentrating on enhancing healthy gut bacteria and their predatory phages, Ancilia develops therapeutic strains that can effectively combat chronic diseases in the fields of immunology and oncology. Additionally, the company is pioneering a new class of live biotherapeutics that allow for the precise targeting of phages or viruses known to induce lysis, thereby advancing treatment options in microbiome-related health conditions.

Repair Biotechnologies, Inc. is a biotechnology company founded in 2018 and based in Syracuse, New York. The company focuses on developing innovative therapies aimed at reversing the progression of age-related conditions such as immunosenescence and atherosclerosis. Utilizing a cholesterol-degrading platform, Repair Biotechnologies creates treatments that address conditions driven by excess or modified cholesterol, including atherosclerosis and familial hypercholesterolemia. Their approach centers on gene therapy and recombinant protein strategies, designed to be safe and well-tolerated, allowing patients to target the underlying causes of diseases associated with cholesterol accumulation.

Octagon Therapeutics, Inc. is a preclinical-stage biopharmaceutical company based in Cambridge, Massachusetts, focused on developing innovative antibiotic medicines for life-threatening autoimmune diseases such as Pemphigus Vulgaris, Systemic Lupus, and Multiple Sclerosis. Established in 2016, the company aims to address multi-drug resistant infections and has demonstrated effectiveness against critical pathogens identified by the World Health Organization. Octagon specializes in creating targeted immunomodulator therapies designed to reset immune homeostasis in patients suffering from chronic autoimmune and inflammatory conditions. By subtly altering the metabolic processes in immune cells during disease, Octagon's medicines aim to selectively target dysregulated immune cells, thus allowing patients to potentially avoid chronic immunosuppression. The company is housed in the Pagliuca Life Lab, adjacent to Harvard University, which facilitates the rapid development of its critical therapies with minimal overhead. With a management team of skilled scientists, clinicians, and entrepreneurs, Octagon Therapeutics is committed to leveraging extensive research experience in drug development to advance its therapeutic innovations.

Circularis Biotechnologies, Inc. is a biotechnology company founded in 2014 and headquartered in Oakland, California. The company specializes in developing innovative methods to regulate gene expression, which enhances the production yields of biotherapeutics. Circularis offers a range of products, including RACRE Variant Libraries, hCMV Variant Library, Protein expression with CMV promoters, and T7 Variant Library. In addition, it provides various services such as RACRE Enhancement, RACRE Discovery, RACRE Technology Access Program, and Ribozyme Analysis of Cis-Regulatory Elements. Through its advanced technologies and services, Circularis aims to improve the efficiency and effectiveness of biotherapeutic production.

Volumetric, Inc. is an advanced biomaterials and biofabrication company based in Houston, Texas, established in 2014. It specializes in developing a 3D bioprinting platform designed to create vascularized human tissue, which can be utilized in various applications such as life sciences, drug discovery, and medical devices. The company offers bioprinters and bioinks that aim to facilitate innovations in biomaterials, cancer research, and the potential replacement of human organs. By focusing on creating materials embedded with living cells, Volumetric is at the forefront of integrating cutting-edge technology into healthcare solutions.

Pragma Bio is a biotechnology company that focuses on developing microbiome-based therapeutics for cancer and autoimmune diseases. Founded in 2018 in Millbrae, California, by Peter McCaffrey, Kovi Bessoff, Ayin Vala, and Kareem Barghouti, the company utilizes proprietary genomic sequencing, artificial intelligence, and synthetic biology techniques to discover biomarkers and therapeutics for complex immunologic disorders. Pragma Bio's platform aggregates both public and private data to create a comprehensive microbiome database, enhancing the ability to identify connections between diverse biological data. This approach not only aids in the discovery of novel biomarkers for patient risk stratification and clinical outcome prediction but also enables the identification of small molecules derived from human-associated bacteria. By leveraging real-world data and advanced analytical processes, Pragma Bio aims to streamline drug discovery and deliver innovative medicines more efficiently and cost-effectively, particularly in relation to the gut-immune axis.

Pragma Bio is a biotechnology company that focuses on developing microbiome-based therapeutics for cancer and autoimmune diseases. Founded in 2018 in Millbrae, California, by Peter McCaffrey, Kovi Bessoff, Ayin Vala, and Kareem Barghouti, the company utilizes proprietary genomic sequencing, artificial intelligence, and synthetic biology techniques to discover biomarkers and therapeutics for complex immunologic disorders. Pragma Bio's platform aggregates both public and private data to create a comprehensive microbiome database, enhancing the ability to identify connections between diverse biological data. This approach not only aids in the discovery of novel biomarkers for patient risk stratification and clinical outcome prediction but also enables the identification of small molecules derived from human-associated bacteria. By leveraging real-world data and advanced analytical processes, Pragma Bio aims to streamline drug discovery and deliver innovative medicines more efficiently and cost-effectively, particularly in relation to the gut-immune axis.

Contraline, Inc. is a biotechnology company based in Charlottesville, Virginia, focused on developing innovative male birth control solutions. The company is pioneering the first long-lasting, non-hormonal, and reversible contraceptive for men. Its primary product, Echo-V, is an ultrasound-visible polymer solution that is injected into the vas deferens, forming a polymer hydrogel device. This device functions as a semi-permeable membrane, effectively blocking sperm while allowing bodily fluids to pass through. Contraline also offers Vasintomy, a non-surgical procedure for the insertion of Echo-V, providing a cost-effective and accessible approach to male contraception. Incorporated in 2015, Contraline aims to transform the landscape of reproductive health for men.

RockStep Solutions is a company specializing in laboratory-management software that aims to enhance data management and operational efficiency in drug discovery. Its flagship platform, Climb, addresses challenges related to data chaos and operational inefficiencies faced by the pharmaceutical and biotechnology sectors, as well as contract research organizations (CROs) and academic institutions. Climb enables users to manage in vivo study data securely in the cloud, providing data assurance, access control, and improved collaboration. This innovative approach helps reduce data silos and enhances the ability of researchers to track and utilize laboratory data effectively. By offering a mobile-friendly solution, RockStep Solutions is transforming the workflow of tier-1 pharmaceutical companies, biotechs, CROs, and academic research environments, ultimately contributing to more efficient drug research and development processes.

Excision BioTherapeutics Inc. is a life science company based in Philadelphia, Pennsylvania, established in 2015. The company is dedicated to the development and commercialization of gene editing therapeutics aimed at treating life-threatening diseases caused by neurotropic viruses. Utilizing CRISPR-based technology, Excision BioTherapeutics focuses on creating advanced gene-editing medicines that can eradicate or disrupt viral genes in human patients. The company's mission is to advance these therapeutics into safe and effective treatments, significantly improving the lives of individuals affected by viral infections globally.

EnClear Therapies, Inc. is a life sciences company based in Newburyport, Massachusetts, that specializes in developing device-based therapies for neurodegenerative diseases. The company focuses on the delivery and monitoring of cerebrospinal fluid (CSF) and employs a proprietary therapeutic platform designed to remove toxic proteins from the CSF. EnClear's initial products are aimed at enhancing the quality of life for patients suffering from conditions such as Amyotrophic Lateral Sclerosis (ALS) and Progressive Supranuclear Palsy (PSP). Incorporated in 2018, EnClear Therapies is dedicated to advancing treatments that can halt disease progression and extend patient lives.

Foresight Mental Health is a technology-driven provider of psychiatry and therapy services, operating a network of clinics dedicated to mental health and wellness. The company employs a diverse team that includes psychiatrists, therapists, and psychiatric nurse practitioners who deliver care directly to patients. Foresight enhances its treatment offerings through innovative technology developed in collaboration with software and biomedical engineers, aimed at transforming the mental healthcare experience. By utilizing comprehensive patient profiles and a database of scientific research, the company conducts detailed analyses that include genetic profiles and assessments of brain-chemical balance. This holistic approach enables Foresight to offer tailored treatments, ultimately helping patients achieve improved mental health and overall well-being.

Ombre is a company that specializes in microbiome testing, providing a testing kit that combines personalized probiotics with microbiome analysis. The company's offerings include subscription-based customized testing, which delivers science-backed probiotics tailored to individual needs. This approach aims to provide actionable insights for the prevention of chronic diseases such as obesity, cystic fibrosis, and Alzheimer's. By focusing on the root causes of gut health issues, Ombre enables customers to better understand and improve their microbiome, promoting overall wellness.

Suggestic, Inc. is a San Francisco-based company founded in 2014 that specializes in automated and personalized lifestyle and nutrition coaching. Its platform leverages proprietary artificial intelligence to create tailored diet plans that cater to users' individual goals, dietary preferences, and restrictions. The application facilitates precision eating by offering personalized meal plans, smart shopping lists, recipe suggestions, and restaurant recommendations. By encoding dietary programs as rulesets, Suggestic enables health-related organizations to efficiently build and deliver customized nutrition programs through white label solutions or direct API integration. The platform also supports data acquisition from users through assessments and lab tests, allowing it to provide relevant food recommendations that assist individuals in weight management, enhancing vitality, and preventing or reversing chronic diseases.

Ombre is a company that specializes in microbiome testing, providing a testing kit that combines personalized probiotics with microbiome analysis. The company's offerings include subscription-based customized testing, which delivers science-backed probiotics tailored to individual needs. This approach aims to provide actionable insights for the prevention of chronic diseases such as obesity, cystic fibrosis, and Alzheimer's. By focusing on the root causes of gut health issues, Ombre enables customers to better understand and improve their microbiome, promoting overall wellness.

Intelligent Implants is a bioelectronics company based in Cork, Ireland, founded in 2014 by Erik Zellmer, Rory Murphy, Martin Larsson, and John Zellmer. The company specializes in wireless implantable electronics designed to stimulate, steer, and monitor bone growth. Its innovative electrotherapeutic devices provide solutions to treat diseases and facilitate the recovery of bone and other tissues. By integrating data, engineering, and medical expertise, Intelligent Implants develops active and connected medical devices that enhance patient treatment and support healthcare professionals in decision-making. The company's technology allows for the acceleration and adjustment of bone growth, enabling healthcare providers to utilize electro-therapeutics to manage patient conditions effectively.

Leucadia Therapeutics Inc. is a privately-held, pre-clinical stage company based in Riverside, California, dedicated to the prevention and treatment of Alzheimer's disease. The company manufactures an implantable device called Arethusta, which restores cerebrospinal fluid (CSF) flow across the cribriform plate. This restoration improves the clearance of toxic metabolites from the brain's earliest affected regions, potentially preventing the onset of Alzheimer's disease. Additionally, Leucadia is developing a diagnostic algorithm that utilizes big data to assess Alzheimer's disease risk, further enhancing its capabilities in addressing this complex condition.

OccamzRazor is a biotechnology company that leverages machine learning and advanced biological techniques to enhance drug discovery and development processes. The company employs two proprietary technologies: Panoramic AI and RazorBrain. These tools work together to extract data from unstructured text sources, such as publications and patient-reported outcomes, and integrate it with structured data like genomics, proteomics, and phenomics. This integration aims to generate robust hypotheses for drug discovery and provide valuable insights into therapeutic strategies. OccamzRazor's applications include extracting and curating biomedical text data, identifying novel targets, and repurposing existing drugs. The company is particularly focused on developing neuroscience therapeutics, with a notable emphasis on Parkinson's Disease.

EnClear Therapies, Inc. is a life sciences company based in Newburyport, Massachusetts, that specializes in developing device-based therapies for neurodegenerative diseases. The company focuses on the delivery and monitoring of cerebrospinal fluid (CSF) and employs a proprietary therapeutic platform designed to remove toxic proteins from the CSF. EnClear's initial products are aimed at enhancing the quality of life for patients suffering from conditions such as Amyotrophic Lateral Sclerosis (ALS) and Progressive Supranuclear Palsy (PSP). Incorporated in 2018, EnClear Therapies is dedicated to advancing treatments that can halt disease progression and extend patient lives.

Blue Mesa Health Inc. is a digital therapeutics company focused on diabetes prevention through its innovative platform, Transform. Founded in 2015 and based in New York, the company provides a comprehensive solution that combines health coaching, behavioral psychology, and technology to help individuals reverse prediabetes and manage their health. Transform offers a weight loss program and weekly lessons, delivering evidence-based behavioral interventions in a flexible format. The company's mission extends beyond the United States, as it has launched its services in Latin America and the Middle East, aiming to become a global leader in culturally diverse, technology-driven health solutions. Blue Mesa Health operates as a subsidiary of Virgin Pulse, Inc.

Blue Mesa Health Inc. is a digital therapeutics company focused on diabetes prevention through its innovative platform, Transform. Founded in 2015 and based in New York, the company provides a comprehensive solution that combines health coaching, behavioral psychology, and technology to help individuals reverse prediabetes and manage their health. Transform offers a weight loss program and weekly lessons, delivering evidence-based behavioral interventions in a flexible format. The company's mission extends beyond the United States, as it has launched its services in Latin America and the Middle East, aiming to become a global leader in culturally diverse, technology-driven health solutions. Blue Mesa Health operates as a subsidiary of Virgin Pulse, Inc.

Ligandal Inc. is a biotechnology company based in Oakland, California, focused on developing therapeutic nanotechnologies for precision gene delivery. Founded in 2013 and originally known as Ligandal Technology LLC, the company aims to revolutionize the treatment of diseases through its innovative platform that facilitates the discovery and delivery of gene therapies and genetic materials with high precision at both cellular and sub-cellular levels. Ligandal's proprietary ligand discovery engine enables the rapid design of materials that can effectively transport various nucleic acid and protein payloads, including CRISPR and mRNA, to targeted cell types. The company is primarily concentrating its efforts on applications in hematology, immuno-oncology, and infectious diseases, employing peptide-based technologies and non-viral nano-carriers to address gene-related conditions.

Notable Labs, Inc. is a clinical-stage company that specializes in personalized lab testing services for cancer patients, particularly those with brain cancer. Founded in 2014 and based in Foster City, California, the company utilizes its proprietary Predictive Precision Medicines Platform to conduct drug combination experiments on patients' tumors. This platform allows Notable Labs to simulate cancer treatments and predict patient responses to specific therapies, enabling healthcare providers to prioritize combinations of FDA-approved treatments that can be prescribed without the need for clinical trials. By providing detailed reports to physicians, Notable Labs aims to enhance treatment efficacy and expedite therapeutic development for patients.

Echo is a provider of am automated microscope intended for biological research and pathologies. The company's product provides features like inverted images, cell counting, phase contrast, brightfield and fluorescence, enabling customers to have accurate images at a lower cost.

CrowdMed, Inc. is a San Francisco-based company that leverages a prediction market technology to assist in diagnosing complex medical conditions. Founded in 2012, CrowdMed aims to provide patients with streamlined access to diagnostic information for their undiagnosed and chronic symptoms. The company's platform connects patients with a diverse network of medical detectives, including licensed physicians, medical students, and other healthcare professionals, who collaborate to generate diagnostic suggestions. By harnessing the collective intelligence of these experts, CrowdMed offers a collaborative solution for individuals facing unresolved medical issues, ultimately aiming to reduce healthcare costs while maintaining quality care. The platform is designed to empower patients by providing them with insightful answers to their medical challenges through the speed and convenience of online interaction.

Echo is a provider of am automated microscope intended for biological research and pathologies. The company's product provides features like inverted images, cell counting, phase contrast, brightfield and fluorescence, enabling customers to have accurate images at a lower cost.

Echo, we believe health is about people, not pills. That’s why we’ve created a new kind of pharmacy. One that comes to you, not the other way around. We start with being brilliant at fulfilling prescriptions because getting people taking the right medicine is the first step in staying well. But there’s more we can do. It’s not just patients we support, its partners. Together with other like-minded pharmacies, GPs and prescribing services we deliver even more positive experiences. Ultimately, we want to help patients understand and do more for themselves, so together they can make the right decisions with their GPs. And when it comes time to improve our health, we all know more Technology should make the future of health care more human. So ours comes packed with care.

Notable Labs, Inc. is a clinical-stage company that specializes in personalized lab testing services for cancer patients, particularly those with brain cancer. Founded in 2014 and based in Foster City, California, the company utilizes its proprietary Predictive Precision Medicines Platform to conduct drug combination experiments on patients' tumors. This platform allows Notable Labs to simulate cancer treatments and predict patient responses to specific therapies, enabling healthcare providers to prioritize combinations of FDA-approved treatments that can be prescribed without the need for clinical trials. By providing detailed reports to physicians, Notable Labs aims to enhance treatment efficacy and expedite therapeutic development for patients.