Investor directory

Boston Harbor Angels

Boston Harbor Angels is a group of proven business leaders interested in investing a portion of their assets in high growth, early stage companies. The group was formed in February 2004 and since then has made a number of investments in companies in medical devices, IT, consumer products, business products, specialty materials, Internet, aviation, etc. They believe they contribute more than money to the companies they fund and welcome the opportunity to work with entrepreneurs open to take advice, yet having the smarts and determination to make the company successful. Their focus is on early stage companies usually looking to raise $250K to $1.5M, where they can fund a portion of the round and syndicate the deal with other angel groups or early stage venture funds. The stage of the company should be close to commercialization, while the company should have a clear and defensible competitive advantage. They are looking for capital efficient businesses, which can reach profitability with less than $5M of equity investment and provide at least 10X return on the investment within 5 years. They do not invest as a fund - each of their members makes his or her individual investment decision but they collaborate in Due Diligence. They have a deep expertise in the life sciences field where they usually take the position of a lead investor, but are open to any opportunities that can make a strong business case. In some cases they prefer to be the follow on investor if they cannot identify a person with strong expertise within their group. The group’s strategy is directed by an executive committee which consists of 8 people elected by the group: Wayne Griffith (chairman), Bill McPhee, Henry Kay, Jay Schwartz (membership director), Steve Andress, Peter Miller, Don Freeman and Mic Williams (president and founder). The group’s day-to-day operations are managed by Boris Batchvarov (managing director). They receive 20-30 business summaries each month, out of which they select 8 companies to make a personal presentation to their screening committee. The screening committee consists of volunteers from the group. The presentations are 10 min long followed by 10 min Q&A. 4 of the companies are invited to present to the whole group, with the idea to get the people interested and decide to perform a Due Diligence with the companies before making an investment.

Focus

Seed RoundTherapeuticsScale StageSeries BSeries AShow more
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Antonette Ho

Managing Director

Ziad Moukheiber

President and CEO

128 past transactions

Cannuflow

Angel Round in 2005
Cannuflow is the recognized innovation leader in fluid management and access devices for arthroscopy and sports medicine procedures (knee shoulder and hip scopes) Cannuflow has 14 revenue-generating products and sells in over 8 countries. They are continuously innovating to improve surgical efficiency, eliminate preventable complications and lower costs in orthopedics, sports medicine, and other indications, and work with a worldwide network of clinical researchers at top institutions. They have a track record of generating industry leading innovations backed by strong IP that are clinically accepted with clinical and health economics data with exceptional capital efficiency. The funding and valuation below are for expansion capital to grow the Cannuflow cannula business revenues and product development.

Fynalist

Angel Round in 2016
Fynalist operates an online platform for corporate recruiters and talent acquisition professionals to find qualified and active candidates. Its platform serves as a candidate recommendation engine that enables corporate recruiters to access active vetted candidates recommended by other corporate recruiters. The company was founded in 2016 and is based in Newton, Massachusetts.

Cognoptix

Pre Seed Round in 2005
Cognoptix is creating and developing an innovative, non-invasive eye test to assist in the early diagnosis of Alzheimer's Disease. Cognoptix's goal is to provide clinicians with a quick, predictive, reliable, inexpensive, and widely available test, enabling early diagnosis and treatment. The company was founded in 2001 and headquartered in Marlborough, Massachusetts.

Pyramid Biosciences

Angel Round in 2016
Pyramid Biosciences is dedicated to discovering and developing targeted therapeutics for a wide range of disorders that are regulated by the tropomyosin receptor kinase (TRK) family. By precisely and selectively modulating the actions of these fundamental cell surface receptors, we can control the key signaling pathways responsible for a patient’s disease, condition, or symptoms.

TruTouch Technologies

Angel Round in 2005
TruTouch Technologies, Inc. develops, manufactures, and markets networked and noninvasive alcohol testing systems for worksite safety applications. It offers TruTouch, a networked biometric alcohol sensor that uses light through the skin to measure and quantify blood alcohol content while simultaneously verifying user identity with biometrics. The company offers products for energy, transportation, warehousing, and community sectors. TruTouch Technologies, Inc. was founded in 2005 and is based in Sudbury, Massachusetts with a research and development center in Riverside, California.

Incentive Targeting

Angel Round in 2007
Incentive Targeting partners with retail chains to provide a targeted marketing service to manufacturers of grocery and consumer products. Using its service, manufacturers market directly to individual shoppers across our entire retail network—based on each person's detailed purchase history. Promotions are delivered via any available distribution channels, such as email, direct mail, or register tape.

Neuraly

Angel Round in 2016
Neuraly, Inc. develops and discovers drugs for the treatment of diseases such as Parkinson’s disease, Alzheimer’s disease and other neurodegenerative disorders. It develops NLY01, a neuroprotective agent for neurologic disorders that blocks pathological activation of microglia in animal models of neurodegenerative diseases, including Parkinson’s as well as develops NLY02 and NLY03 that are blood–brain barrier (BBB) penetrating kinase inhibitors. Neuraly, Inc. was founded in 2016 and is based in Germantown, Maryland. The company operates as a subsidiary of D&D Pharmatech Co., Ltd.

Platelet BioGenesis

Angel Round in 2015
Platelet BioGenesis, Inc. operates as a biotechnology company that produces commercial scale donor-independent human platelets from pluripotent stem cells for clinical application. The company develops a microfluidic bioreactor, which includes generation of functional platelets from human stem cell cultures at scale. It distributes bioreactor platelets to hospitals and blood banks to give to patients worldwide. The company was founded in 2014 and is based in Cambridge, Massachusetts.

Emovi

Angel Round in 2007
Emovi is dedicated to providing the highest quality, most technologically advanced products for knee joint assessment to restore patient quality of life. they are a company of knowledgeable, dedicated team members committed to innovation in healthcare.

Julianna Rae

Angel Round in 2006
Julianna Rae is a Provider of an online retail platform for women apparel. The company offers a range of clothes and intimate apparel to meet the fit and fashion needs of women and eco-conscious buyer.

Avaxia Biologics

Series B in 2012
Avaxia Biologics, Inc. operates as a biopharmaceutical company that develops oral antibody therapeutics. It offers gastrointestinal diseases, such as inflammatory bowel diseases, celiac disease, necrotizing enterocolitis, radiation syndrome, oral mucositis, and diabetes and obesity. Avaxia Biologics, Inc. has a strategic collaboration with Courtagen Life Sciences, Inc. The company was founded in 2005 and is based in Lexington, Massachusetts. Avaxia Biologics, Inc. operates as a subsidiary of Circle33 LLC.

CleanFiber

Seed Round in 2013
CleanFiber, LLC develops cellulose insulation materials for attics, walls, and floors of residential and commercial new construction and retrofit applications. CleanFiber, LLC was formerly known as UltraCell Insulation, LLC and changed its name to CleanFiber, LLC in September 2018. The company was incorporated in 2013 and is based in Blasdell, New York with additional office in Buffalo, New York.

Gramify

Angel Round in 2016
Gramify is personalized audio greetings that feature the voice of celebrities and fictional characters. These are emotionally-engaging alternatives to print cards and ecards. They are bought online and delivered either through a phone call or through Facebook. They started signing licenses and are negotiating with major brands. The best part is the team which include licensing heavyweights who have done hundreds of deals.

Incentive Targeting

Series A in 2010
Incentive Targeting partners with retail chains to provide a targeted marketing service to manufacturers of grocery and consumer products. Using its service, manufacturers market directly to individual shoppers across our entire retail network—based on each person's detailed purchase history. Promotions are delivered via any available distribution channels, such as email, direct mail, or register tape.

RedDress

Angel Round in 2010
RedDress is a medical device company that developed a wound care product that helps the human body on the wound healing process. It specializes in wound care, wound healing, tissue repair, regenerative medicine, chronic ulcers, diabetic and foot ulcers. The company was founded in 2009 and headquartered in Tel Aviv, Israel.

scrible

Angel Round in 2011
scrible, Inc. develops an online reading and research software that enables users to bookmark Webpages in the cloud. Its cloud-based service allows Internet users to annotate Web pages in various browsers, and manage and collaborate on them online. The company was incorporated in 2009 and is headquartered in San Mateo, California.

Tetragenetics

Angel Round in 2005
Tetragenetics, Inc. is an early-stage biotechnology company meeting the needs of customers who seek a cost-effective alternative platform technology for the production of genetically engineered proteins. Their technology is particularly well suited to the production of eucaryotic membrane and secretory proteins that are difficult to express in conventional systems. Such proteins include vaccine antigens, monoclonal antibodies, and a variety of therapeutic proteins for the treatment and prevention of human and animal disease.

Respiratory Motion

Angel Round in 2010
Respiratory Motion, Inc., a medical device company, focuses on the development and commercialization of medical devices to monitor respiratory variation. It offers ExSpiron, a point-of-care device that measures and provides quantitative values for the vital parameters of the respiratory function, such as minute ventilation, tidal volume, and respiratory rate. The company was incorporated in 2011 and is based in Waltham, Massachusetts.

ConveyIQ

Angel Round in 2010
ConveyIQ, Inc provides a cloud-based candidate engagement platform, which allows recruiters and employers to screen and communicate with candidates using video technology. The company was incorporated in 2010 and is based in New York, New York. As of August 26, 2019, ConveyIQ, Inc. operates as a subsidiary of Entelo, Inc.

Corbus Pharmaceuticals

Angel Round in 2010
Corbus Pharmaceuticals, Inc. develops and commercializes therapeutics for the treatment of inflammatory fibrotic diseases. Its product includes Resunab, an orally bioavailable synthetic CB2 agonist. The company was founded in 2014 and is based in Norwood, Massachusetts. Corbus Pharmaceuticals, Inc. operates as a subsidiary of Corbus Pharmaceuticals Holdings, Inc.

ImageRights International, Inc.

Angel Round in 2009
ImageRights International provides intelligent image search and copyright enforcement services to photo agencies and professional photographers worldwide to ensure that their intellectual property rights are protected and that they are compensated for the unauthorized use of their copyrighted works. ImageRights, the only company to have fully automated copyright registration with the US Copyright Office, has made copyright enforcement a truly integrated component of its clients' daily workflow.

Blurr

Seed Round in 2013
Conceal, share & reveal photos in a fresh new way on Blurr for iOS. BLURR combines three of the most popular social media activities together -- sharing, gamification and filters -- in a mobile app that places a value on a “like” to unlock content. * The originator uses filters to “blurr” a photo and then sets a certain number of likes required to unlock or “de-blurr” the photo. * Blurr participants can curate and collect content, create profiles, incentivize your existing audiences on any social media platform to engage on BLURR. * Blurr leaderboard will focus on what’s trending within the app, highlighting the most popular photos on BLURR in real time.

SmartCells

Series C in 2007
SmartCells, Inc. designs and develops insulin products. It offers SmartInsulin, a self regulating injectable formulation for treating diabetes. The company's polymer-based dosing technology is used for various applications, such as fertility, thyroid, and growth hormone deficiencies; treatments with poor compliance or therapeutic window issues, such as oncology; and drug-device combinations. SmartCells, Inc. was founded in 2003 and is based in Beverly, Massachusetts.

CoolChip Technologies

Angel Round in 2011
CoolChip Technologies Inc. provides thermal management products. The company provides kinetic cooling solutions; and high performance and low profile coolers. It offers its products for high performance computing servers, medical devices, data centers, or consumer electronics. The company was founded in 2010 and is based in Somerville, Massachusetts.

Archer Roose

Angel Round in 2015
Archer Roose is a re-imagined traditional supply chains to bring you an afternoonified delight at an affordable price.

Xeno Biosciences

Series A in 2021
Xeno Biosciences, Inc. is a biotechnology company provider of novel class of treatments for metabolic diseases. Xeno Biosciences, Inc. operates as a biopharmaceutical company pioneering a novel class of therapeutics to address large unmet needs in metabolic diseases. Lead program, XEN-101, is a first-in-class, oral formulation designed to shift the gut microbiome to the weight-loss associated state induced by Roux-en-Y Gastric Bypass (RYGB) surgery.

Emerginvest

Angel Round in 2008
Emerginvest is a website which helps investors research international stock markets, and then shows them how they can invest there. Emerginvest (a free service) is connecting investors to hundreds of thousands of undiscovered, international companies by providing data, research, and tools on 150+ world stock exchanges. Emerginvest lets anyone — even those who aren't familiar with world markets — find international stocks to invest in. After a few minutes of browsing, investors can find companies in emerging markets like China, or in frontier markets such as Vietnam or Botswana. Once a user finds an investment, Emerginvest can recommend all of the ways that an investor can own that particular stock—whether through suggesting local, English-speaking brokerages, or domestic vehicles such as mutual funds, ETFs, and ADRs.

NextShift Robotics

Angel Round in 2016
NextShift Robotics Inc. designs and develops material handling systems for normal warehouse and manufacturing floor conditions. The company was founded in 2016 and is headquartered in North Billerica, Massachusetts.

XCOR Aerospace

Angel Round in 2007
Founded in 1999, XCOR Aerospace is a small, privately-held California corporation. Their headquarters and development facilities are located at the Mojave Spaceport and Civilian Aerospace Test Center in Mojave, California. XCOR engages in research, development, and production of reusable rocket-powered, horizontal launch vehicles for suborbital, and ultimately, orbital travel.

Oculis Labs

Seed Round in 2007
Oculis Labs Inc. provides a security software that protects computer screens. It offers PrivateEye, a software that protects information against exposure, as well as produces an audit trail showing proof-of-compliance. The company serves governments, enterprises, OEMs, and consumers worldwide. The company was founded in 2007 and is based in Hunt Valley, Maryland. As of April 8, 2015, Oculis Labs Inc. operates as a subsidiary of Optio Labs, LLC.

Cambridge Endoscopic Devices

Seed Round in 2006
Working collaboratively with the surgical community, Cambridge Endo is committed to developing and delivering hand-held instruments that enable easy access and unparalleled control.

Lumo

Angel Round in 2016
At lumo,They’re obsessed with making air travel smarter. They predict flight delays months, weeks, hours ahead of time, making planning easier and flight changes less stressful.

First Light Diagnostics

Angel Round in 2007
First Light Biosciences develops breakthrough automated medical diagnostic products for rapid, sensitive, and cost-effective detection of Healthcare-Associated Infections (HAI). The products address the need for cost-effective and accurate diagnostics to meet the explosive growth in testing. New testing is being driven by clinical studies showing that testing for infectious agents can help to dramatically lower the rate of hospital infections. Based on its proprietary MultiPath detection technology, First Light’s products combine the performance of the most advanced commercial laboratory tests with unprecedented affordability and ease-of-use.

BrandVerge

Angel Round in 2017
BrandVerge is a marketplace + workflow tool that makes it easy for advertisers to plan premium media partnerships at scale. Our platform takes brands from discovery to recommendation in a few easy steps, ultimately bringing relevant buyers to the media companies on BrandVerge! We are the only two-sided solution in the space that proactively increases visibility and new business for our publisher partners, while simultaneously increasing efficiency for our advertisers by 80+%.

The Canary System

Angel Round in 2006
The Canary System is a low-powered, laser-based instrument with an integrated intraoral camera that detects the presence of cracks and caries before they are large enough to appear on dental X-rays. The system also generates a patient report that contains an odontogram with Canary numbers, which are color-coded for the examined teeth, along with the dentist’s treatment recommendation. The Canary System’s reports can also be examined by the patient on The Canary Cloud. Launched in 2006, it is based in Toronto, O.N.

Ionica Sciences

Angel Round in 2014
Ionica Sciences™ is utilizing a new technology platform to meet urgent needs in clinical diagnostics.The ability to rapidly and accurately identify the presence of diseases would provide clinicians with the ability to reduce suffering of their patients, the use of antibiotics, and healthcare costs that result from mis- or missed diagnoses.

ZoomSystems

Angel Round in 2004
ZoomSystems is the global leader in the automated retail industry. Founded in 2002, ZoomSystems develops and operates a valuable, unattended point-of-sale solution for brands and retailers. Its in-store and satellite retail units include integrated hardware, software and managed services to deliver a product from manufacturer to consumer, helping brands increase sales, expand market reach and enhance the consumer experience. The ZoomShop network has grown to more than 1,500 locations in airports, malls, resorts, military bases and retail stores across the US, Canada, Europe and Japan. Top brand and retail partners include Best Buy, Nespresso, Proactiv, Amazon, Essie, Benefit Cosmetics and Albertsons. ZoomSystems is based in San Francisco, CA and investors include Sierra Ventures, Goldman Sachs, Starfish Ventures and NeoCarta Ventures.

Tikatok

Angel Round in 2008
Tikatok is an on line community designed for children to write, illustrate and publish their own stories into real books. Tikatok was started by two moms that felt it is essential to give young children a place to channel their creativity and publish their work. For less than $20, children can self-publish their own paperback or hardcover book. With the help of "story sparks," a template-based system, children can easily start writing and illustrating stories. They can upload art directly to the site or mail it in. There are packages to schools and libraries for group orders. The site is very family centered, and has an awesome and well-thought-out privacy policy.

GoodTwo

Angel Round in 2016
GoodTwo is a platform that allows fundraisers to run campaigns using group buying deals to generate donations. Fundraisers of any size, from individuals raising money for a cause to school/community groups to large nonprofits, can set up a free fundraising page and select up to three deals at local and national brands. These deals, negotiated in advance by GoodTwo, are the same as those you'd find on group buying sites such as Groupon, LivingSocial, and GoodTwo's parent company, CoupMe (a New England-based deal a day site). The fundraisers then uses tools available through GoodTwo as well as their own donor list to let potential donors know about the fundraiser. For every deal sold, half the profits that GoodTwo receives are given as a donation. (The donation for each deal is clearly spelled out in the buying process.) All fulfillment, customer service, deal negotiation, etc. is handled by GoodTwo. The fundraiser simply extends the offers to its database.

eSight

Angel Round in 2007
eSight Corporation manufactures wearable electronic glasses for the blind. Its eyewear helps people with macular degeneration, retinopathy of prematurity, diabetic retinopathy, and other eye conditions. The company also offers a headset, which houses a high-definition camera, OLED screens, and supporting technologies used to capture and display a real-time video feed; and The Controller, a lightweight processing unit for adjusting pixels of the video in real time. It serves customers in Canada and the United States. eSight Corporation was incorporated in 2006 and is based in Toronto, Canada with additional offices in Ottawa, Canada; Los Angeles, California; Nashville, Tennessee; and Switzerland.

ZetrOZ

Angel Round in 2010
ZetrOZ is revolutionizing the ultrasound industry by introducing proprietary generator technology that is more efficient, more portable, and more economically viable than any ultrasound generator presently available.

Myomo

Venture Round in 2009
Myomo, Inc., a wearable medical robotics company, designs, develops, and produces myoelectric orthotics for people with neuromuscular disorders in the United States. The company offers MyoPro, a myoelectric-controlled upper limb brace orthosis product used for supporting a patient’s weak or paralyzed arm to enable and enhance functional activities of daily living, ADLs, in the home and community. Its products are designed to help restore function in individuals with neuromuscular conditions due to brachial plexus injury, stroke, traumatic brain injury, spinal cord injury, and other neurological disorders. The company sells its products to orthotics and prosthetics providers, the Veterans Health Administration, rehabilitation hospitals, and distributors. Myomo, Inc. was incorporated in 2004 and is headquartered in Cambridge, Massachusetts.

Cognoptix

Angel Round in 2006
Cognoptix is creating and developing an innovative, non-invasive eye test to assist in the early diagnosis of Alzheimer's Disease. Cognoptix's goal is to provide clinicians with a quick, predictive, reliable, inexpensive, and widely available test, enabling early diagnosis and treatment. The company was founded in 2001 and headquartered in Marlborough, Massachusetts.

Vizibility

Series A in 2011
Vizibility helps people package and promote their online presence with a powerful Mobile Business Card. Build trust and credibility quickly when you make an accurate, powerful and lasting impression. Your mobile business card is like a personalized, mobile-friendly website with key content about you and your organization. It's instantly accessible from any smartphone without an app. And it's a snap to share using QR codes and Microsoft Tag barcodes, NFC mobile wallet cards, Apple Passbook and special buttons and links. Vizibility's mobile identity management platform is integrated and resold by printers and web-to-print vendors which are seeking to offer valuable new features, generate new revenue streams and differentiate themselves from competitors. U.S. Patents 7,831,609, 7,987,173, 8,095,534, 8,271,650, 8,275,837 and 8,280,879. Other patents pending.

RevBio

Convertible Note in 2018
RevBio is commercializing an injectable, self-setting bone adhesive that can bond bone to bone and bone to metal to stabilize implant devices. Over time, the adhesive biodegrades and is replaced by new bone. This unique material will reduce the duration and complexity of medical procedures, allow for more minimally invasive surgeries, and will improve patient outcomes by reducing recovery time and the overall cost of care.

Newfield Design

Series A in 2012
Newfield Design is a Maine, US based company that designs, develops and manufactures communications systems infrastructure. The founders have decades of experience in successful communications system design, development, deployment and management, particularly with Public Safety, Commercial/SMR and Critical Infrastructure communications systems.

Avaxia Biologics

Series A in 2012
Avaxia Biologics, Inc. operates as a biopharmaceutical company that develops oral antibody therapeutics. It offers gastrointestinal diseases, such as inflammatory bowel diseases, celiac disease, necrotizing enterocolitis, radiation syndrome, oral mucositis, and diabetes and obesity. Avaxia Biologics, Inc. has a strategic collaboration with Courtagen Life Sciences, Inc. The company was founded in 2005 and is based in Lexington, Massachusetts. Avaxia Biologics, Inc. operates as a subsidiary of Circle33 LLC.

DetraPel

Seed Round in 2019
DetraPel, Inc. produces hydrophobic liquid repellent spray to protect objects from spills and stains. The company was founded in 2013 and is based in Framingham, Massachusetts.

SmartCells

Series D in 2009
SmartCells, Inc. designs and develops insulin products. It offers SmartInsulin, a self regulating injectable formulation for treating diabetes. The company's polymer-based dosing technology is used for various applications, such as fertility, thyroid, and growth hormone deficiencies; treatments with poor compliance or therapeutic window issues, such as oncology; and drug-device combinations. SmartCells, Inc. was founded in 2003 and is based in Beverly, Massachusetts.

Astrocyte Pharmaceuticals

Seed Round in 2017
Astrocyte Pharmaceuticals Inc., a small drug development company, develops neuroprotection therapies for traumatic brain injuries (TBI), concussions, acute ischemic stroke, neurodegenerative disorders, and other injuries to the brain. It offers AST-004, a novel small molecule for acute administration of patients that protects and repairs neurons that are damaged by selectively stimulating astrocytes. Astrocyte Pharmaceuticals Inc. was incorporated in 2014 and is based in Cambridge, Massachusetts.

Astrocyte Pharmaceuticals

Series B in 2023
Astrocyte Pharmaceuticals Inc., a small drug development company, develops neuroprotection therapies for traumatic brain injuries (TBI), concussions, acute ischemic stroke, neurodegenerative disorders, and other injuries to the brain. It offers AST-004, a novel small molecule for acute administration of patients that protects and repairs neurons that are damaged by selectively stimulating astrocytes. Astrocyte Pharmaceuticals Inc. was incorporated in 2014 and is based in Cambridge, Massachusetts.

1908 Brands

Angel Round in 2011
1908 Brands manufactures, manages, and markets natural product brands such as Boulder Clean, CompoKeeper, thrive TRIBE, Fruitivity Snacks, Schultz’s, Pasta Jay’s, and Yummari. The values of the company are trust, adaptiveness, passion, knowledge, efficiency, and collaborative. 1908 Brands was founded in 2010 by Steve Savage. The company is based in the United States.

BioArray

Seed Round in 2005
BioArray turns raw data collected from diverse health monitoring solutions into genuinely useful information for consumers; translating insight into non-medical jargon that users find more meaningful.

SmartCells

Series A in 2004
SmartCells, Inc. designs and develops insulin products. It offers SmartInsulin, a self regulating injectable formulation for treating diabetes. The company's polymer-based dosing technology is used for various applications, such as fertility, thyroid, and growth hormone deficiencies; treatments with poor compliance or therapeutic window issues, such as oncology; and drug-device combinations. SmartCells, Inc. was founded in 2003 and is based in Beverly, Massachusetts.

Voice Genesis

Venture Round in 2004
Voice Genesis is a mobile messaging software company.

Wasabi

Angel Round in 2007
At Wasabi, they bring you food that embodies all of these things — simple, flavorful, and healthy. Modern Japanese cuisine isn’t complicated. They use fresh, simple ingredients that put a tingle on your tongue with their essential flavors — raw fish, zesty soy, and seaweed with attitude.

Chromis Fiberoptics

Angel Round in 2004
Chromis is pioneering the use of high-performance plastic optical fibers to deliver data at the speed of light, filling needs for economical, high-bandwidth, short-distance data/video links in data center, professional audio/video, consumer electronics, and other high-performance computing applications. Chromis also produces specialty optical fibers and custom cables for medical, industrial sensing and a variety of other applications. Their core technology is protected by over a dozen U.S. and foreign patents and patents-pending.

GateRocket

Seed Round in 2005
GateRocket, Inc. provides verification and debugging solutions for FPGAs. It offers RocketDrive, a device native verification system for complex FPGAs, which accelerates verification throughput and identifies problems with IP blocks, pin-outs, and tool chain anomalies. The company also provides RocketVision, a FPGA debug solution that automates test point insertion and detects differences between RTL and FPGA devices. The company was incorporated in 2003 and is headquartered in Bedford, Massachusetts.

Bliss Health

Seed Round in 2011
Bliss Health offers care management services through a network of integrated medical, nursing, and home care services.

Chronix Biomedical

Seed Round in 2004
Chronix Biomedical is pioneering a breakthrough approach to the diagnosis and management of chronic diseases and cancer. It has developed proprietary technology that measures and categorizes circulating nucleic acids, DNA sequences circulating in the blood that are associated with specific changes in disease and health status. Chronix plans to collaborate with a variety of partners to develop and market its DNA-based assays that have the potential to transform the management of a broad range of cancers and other conditions. Chronix is headquartered in San Jose, California and has research facilities in Germany.

Powerplay

Seed Round in 2020
Mobile-based operating system to manage construction & architectural projects. PowerplayOS is a mobile app ecosystem that simplifies site-to-office communication to manage construction & architectural projects. Simplifying communication like- Material requests Material inwarding notes Goods receiving notes Planned schedule Highlights, issues, RFIs, RFAs and more

SmartCells

Series D in 2010
SmartCells, Inc. designs and develops insulin products. It offers SmartInsulin, a self regulating injectable formulation for treating diabetes. The company's polymer-based dosing technology is used for various applications, such as fertility, thyroid, and growth hormone deficiencies; treatments with poor compliance or therapeutic window issues, such as oncology; and drug-device combinations. SmartCells, Inc. was founded in 2003 and is based in Beverly, Massachusetts.

3Derm Systems

Angel Round in 2012
3Derm Systems, Inc., a 3D dermatology company, offers a special tool that takes high resolution 3D photos of the skin. It offers a handheld skin imager and the cloud-based software to take, store, and send clinical quality 3D images from any user to a trained dermatologist. The company was founded in 2011 and is based in Boston, Massachusetts. As of August 18, 2020, 3Derm Systems, Inc. operates as a subsidiary of Digital Diagnostics, Inc.

Siamab Therapeutics

Series B in 2014
Siamab Therapeutics is a biopharmaceutical company that develops therapies targeting abnormal carbohydrates found only on cancer cells. It has developed a platform of technologies that enables the discovery and development of anti-TACA therapeutic antibodies. The company’s core technologies were licensed from the laboratory of Ajit Varki, a professional in glycobiology and sialic-acid biochemistry. It has brought together a team of scientists and advisors in oncology, glycoimmunology, and antibody engineering to support its anti-TACA antibody discovery and development programs. Siamab Therapeutics was founded in 2006 and is headquartered in Newton, M.A.

ImmuneXcite

Series A in 2012
Immunexcite, Inc., a biopharmaceutical company, develops monoclonal antibodies for cancer. The company develops monoclonal antibodies by employing its mAbXcite, an immunotherapy platform technology that targets cancer cells for destruction by engaging neutrophils. Immunexcite, Inc. was founded in 2007 and is based in Lexington, Massachusetts.

Nomir Medical Technologies

Angel Round in 2006
Nomir Medical Technologies, Inc. is a medical device company with a pipeline of optical energy therapies.

WebNotes

Angel Round in 2008
WebNotes helps people manage the deluge of online content they sift through every day by providing users with a virtual highlighter and sticky note tool that can be used to make annotations directly on any web page. These tools eliminate the need to repeatedly copy & paste information into a word document or e-mail, or sort through hundreds of bookmarks. Users' annotations are automatically saved to their WebNotes accounts for later reference, and can be searched, organized, and shared with others at any point in time.

Zylö Therapeutics

Series B in 2022
Zylö Therapeutics offers an innovative sustained-release drug-delivery system that was developed by Joel Friedman MD PhD, Adam Friedman MD FAAD, and Andrew Draganski PhD. The delivery system uses patented hydrogel-derived nanoparticles, called Nanopods™, to deliver—in a sustained and controlled manner—notoriously hard-to-deliver therapeutic agents through topical administration. The company was founded in 2017 and based in Greenville, South Carolina.

StylePath

Angel Round in 2007
StylePath is a shopping recommendation engine aimed at fashion, accessories, and home furnishings. It helps shoppers find items to their taste with a patented machine-learning algorithm, and also offers several other features, such as Window Shopping, which "feeds" shoppers a stream of products it thinks they'll find interesting. Other companies in this space include eBay, with its new Neighborhoods product, and fellow Boston-based start-up [StyleFeeder](http://www.crunchbase.com/organization/stylefeeder).

SmartCells

Series A in 2005
SmartCells, Inc. designs and develops insulin products. It offers SmartInsulin, a self regulating injectable formulation for treating diabetes. The company's polymer-based dosing technology is used for various applications, such as fertility, thyroid, and growth hormone deficiencies; treatments with poor compliance or therapeutic window issues, such as oncology; and drug-device combinations. SmartCells, Inc. was founded in 2003 and is based in Beverly, Massachusetts.

Aircuity

Venture Round in 2004
Aircuity manufactures integrated sensing and control solutions that cost-effectively reduce building energy and operating expenses while simultaneously improving its indoor environmental quality. Aircuity's first product, a portable air monitoring system known as OptimaTM, it was developed in collaboration with Environmental Health & Engineering, the primary research contractor for the EPA's Indoor Environments Division. It was incorporated in 2000 and is headquartered in Newton, Massachusetts.

SepSensor

Angel Round in 2004
The SepSensor Monitoring System monitors the condition of grease interceptors around the clock. SepSensor is initially focused on grease interceptor monitoring for the food service industry.

CytoAgents

Angel Round in 2019
CytoAgents, Inc., a biotechnology company, manufactures protein based drugs for the treatment of influenza and other viral infectious diseases. The company offers GP1681, an agonist of a G-protein coupled receptor. CytoAgents, Inc. was incorporated in 2018 and is based in Pittsburgh, Pennsylvania.

Nano-C

Angel Round in 2004
Nano-C, Inc. develops and manufactures nanostructured carbon materials for use in energy and electronics applications. The company offers carbon nanotubes, which includes single walled carbon nanotubes (SWCNT), fullerenes, and fullerene derivatives. Its products are used in various markets and applications around the world, including displays and touch screens, carbon electronics, renewable energy, semiconductor manufacturing, and sensors. Nano-C, Inc. was founded in 2001 and is based in Westwood, Massachusetts.

Testive

Angel Round in 2011
Testive is at the forefront of developing education products that blend teachers and technology. Their private tutoring products use technology to deliver one-on-one instruction at lower cost than any other private instruction model. Over 30K students and teachers have used their test preparation technologies to help them to help them on their preparation journey. Their core platform and approach was developed at MIT to speed up the learning feedback cycle. Testive is based in Cambridge, MA with offices in Durham, NC and is an alumnus of the TechStars Boston accelerator program.

Enrich Therapeutics

Seed Round in 2020
Enrich Therapeutics Inc. develops a single cell isolation technology for global life science research. It offers LASUM, a LCD aided selection under microscope single cell isolation technology to work on suspension cells, adherent cells, and non-ideal tissue cell samples. Its life science tool improves scalability and affordability in applications, such as antibody drug discovery, NGS, and adoptive cell therapy development. The company also provides phage display library engineering/construction, affinity-on-demand binder selection, cell line development for CAR-T immunotherapy, B-cell isolation, adoptive cell therapy development, cell surface antibody discovery, and precision cell isolation for NGS analysis. The company was founded in 2018 and is based in Worcester, Massachusetts.

Windgap Medical

Angel Round in 2011
WindGap Medical is a biotech company that manufactures medical devices used to treat patients with severe allergies. The company develops auto-injectors that are filled with heat-stable epinephrine that enable physicians to inject it into a patient suffering from anaphylaxis due to an acute allergy attack. The company was established in 2011 and is headquartered in Somerville, Massachusetts.

Xeno Biosciences

Angel Round in 2015
Xeno Biosciences, Inc. is a biotechnology company provider of novel class of treatments for metabolic diseases. Xeno Biosciences, Inc. operates as a biopharmaceutical company pioneering a novel class of therapeutics to address large unmet needs in metabolic diseases. Lead program, XEN-101, is a first-in-class, oral formulation designed to shift the gut microbiome to the weight-loss associated state induced by Roux-en-Y Gastric Bypass (RYGB) surgery.

PawSpot

Angel Round in 2007
First, on PawSpot a human profile is included along with a pet profile, and users are encouraged to become “friends”. PawSpot seems to be aiming to provide much needed services to pet owners. In particular, arranging for friends to take care of each other’s pets while away on vacation, and finding local dog parks.

RevBio

Angel Round in 2014
RevBio is commercializing an injectable, self-setting bone adhesive that can bond bone to bone and bone to metal to stabilize implant devices. Over time, the adhesive biodegrades and is replaced by new bone. This unique material will reduce the duration and complexity of medical procedures, allow for more minimally invasive surgeries, and will improve patient outcomes by reducing recovery time and the overall cost of care.

SmartCells

Angel Round in 2003
SmartCells, Inc. designs and develops insulin products. It offers SmartInsulin, a self regulating injectable formulation for treating diabetes. The company's polymer-based dosing technology is used for various applications, such as fertility, thyroid, and growth hormone deficiencies; treatments with poor compliance or therapeutic window issues, such as oncology; and drug-device combinations. SmartCells, Inc. was founded in 2003 and is based in Beverly, Massachusetts.

AisleBuyer

Angel Round in 2009
AisleBuyer is a mobile shopping platform that dramatically improves the in-store retail shopping experience by leveraging SmartPhone technology to unite the best features of both "bricks" and "clicks" retailing. Our virtual shopping assistant, "location aware" digital circular, and first ever mobile self-checkout system provides retailers with an end-to-end solution designed to increase sales, reduce costs and gain unprecedented analytical insight into in-store shopping behavior. A simple product scan provides consumers with valuable product info, targeted offers and a mobile self-checkout option -- meaning they will never have to wait in line again.

ReDigi

Venture Round in 2011
ReDigi is the online marketplace for pre-owned digital music and the only Cloud service that verifies whether each music file uploaded for storage was legally acquired from an eligible source. ReDigi's patent pending methods are revolutionary. In addition to the highly sophisticated Verification Engine, the Atomic Cloud transfer system enables the transfer of a digital music file between buyer and seller without copying or file sharing. In addition to these technological breakthroughs, ReDigi supports artists directly through a unique platform that, for the first time in the secondhand music market, grants generous payments from each track sold (and resold) directly to the artist who created it.

Horizontal

Angel Round in 2004
Horizontal Integration designs strategic digital marketing and staffing solutions for Fortune 500 companies. It is a certified Minority Business Enterprise with offices in Minneapolis, Denver, Dallas, Indianapolis, Vadodara, Bangalore, Dubai, and Kuala Lumpur. Horizontal Integration was founded in 2003.

Anubis Bio

Angel Round in 2018
Anubis Bio Corporation, a medical nutrition company, develops and manufactures products to control diarrhea in dogs and cats. It offers DoggyStat, a products that provides symptomatic relief and eliminates diarrhea causing infections in dogs and cats. Anubis Bio Corporation was incorporated in 2018 and is based in Orlando, Florida.

Akston Biosciences

Angel Round in 2012
Akston Biosciences Corporation develops insulin for the treatment of diabetes and cancer. The company offers biologic therapeutics such as AKS-107, a disrupt insulin autoimmunity to prevent type 1 diabetes; AKS-446, a novel vaccine to prevent the development of coronavirus disease; AKS-130, ultra-long acting, once-per-week insulin for treating type 1 and type 2 diabetes; AKS-161C and AKS-162D for the treatment of diabetes in cats and dogs; AKS-231, a glucose-responsive insulin for treating type 1 and type 2 diabetes; and AKS-301 for cancer therapy. The company was incorporated in 2011 and is based in Beverly, Massachusetts.

Newfield Design

Seed Round in 2011
Newfield Design is a Maine, US based company that designs, develops and manufactures communications systems infrastructure. The founders have decades of experience in successful communications system design, development, deployment and management, particularly with Public Safety, Commercial/SMR and Critical Infrastructure communications systems.

Motus Games

Angel Round in 2004
Motus games was born in 2001, when a bunch of guys from MIT decided to bring immersive interaction and control to gamers. Unfortunately, the world didn't seem to be ready for motion based control. No one seemed to think anyone would get off the couch to play a video game. They felt this was odd considering that their first implementation allowed you to control a light saber – in their view, the holy Grail of all gaming. So off into storage the controllers went (truthfully, they went home with a few of the hard-core gamers for thousands of hours of unofficial testing). In the meantime, they focused on advanced motion capture technology in sports (iClub.net). Then a year ago or so, something called the Wii took off and all of a sudden it seems like the world was ready for what they have to offer. So here they are, seven years later (…talk about being way ahead of a technology curve) and they're bringing out a next generation controller for everyone to enjoy. Take a few minutes and check out their site and the newest evolution of motion control, codename Darwin.

Green Piñata LLC

Angel Round in 2015
Green Pinata is an online subscription service that rents world's best educational and safe toys for children under 5 years.

Chasma Interactive Publishing

Venture Round in 2004
Chasma Interactive Publishing engages in developing, publishing, and distributing applications and interactive entertainment software.

Mosaic Storage Systems

Seed Round in 2012
Mosaic Storage Systems is a provider of digital asset storage services used to help professional photographers to store their photographs. Its digital asset storage services take digital copies of photographs, stores them on its servers, and make them accessible via the internet that enables users to store and share photographs securely. It was founded in 2011 and is based in Nashua, New Hampshire.

Siva Therapeutics

Venture Round in 2012
Siva Therapeutics Inc., a biotechnology company, engages in the development of nanotechnology approaches for the treatment of cancer. It develops SivaRods, a photo thermal device, which uses heat to irreversibly damage solid tumor tissues. The company was founded in 2011 and is based in Boulder, Colorado.