Boston Harbor Angels

Boston Harbor Angels is an angel investment group based in Boston, Massachusetts, established in 2004. Composed of experienced business leaders, the group focuses on investing in high-growth, early-stage companies across various sectors, including life sciences, information technology, consumer products, and clean technologies. The organization typically invests in companies seeking between $250,000 and $1.5 million, emphasizing those nearing commercialization with a clear competitive advantage. Boston Harbor Angels aims to partner with entrepreneurs who are open to guidance while demonstrating the ambition and capability to drive their businesses towards success. The group collaborates in the due diligence process, with each member making individual investment decisions. They receive numerous business proposals each month, from which they carefully select a few for presentations, ultimately inviting the most promising companies to present to the entire group for potential investment discussions.

122 past transactions

Zylö Therapeutics

Series B in 2022
Zylö Therapeutics offers an innovative sustained-release drug-delivery system that was developed by Joel Friedman MD PhD, Adam Friedman MD FAAD, and Andrew Draganski PhD. The delivery system uses patented hydrogel-derived nanoparticles, called Nanopods, to deliver—in a sustained and controlled manner—notoriously hard-to-deliver therapeutic agents through topical administration. The company was founded in 2017 and is based in Greenville, South Carolina.

Xeno Biosciences

Series A in 2021
Xeno Biosciences operates as a biopharmaceutical company pioneering a novel class of therapeutics to address large unmet needs in metabolic diseases. Lead program, XEN-101, is a first-in-class, oral formulation designed to shift the gut microbiome to the weight-loss associated state induced by Roux-en-Y Gastric Bypass (RYGB) surgery. It was founded in 2015 and is headquartered in Somerville, Massachusetts.

Enrich Therapeutics

Seed Round in 2020
Enrich Therapeutics is a biotechnology startup focused on the development of novel single-cell isolation platform along with the critical life science applications.

Powerplay

Seed Round in 2020
Mobile-based operating system to manage construction & architectural projects. PowerplayOS is a mobile app ecosystem that simplifies site-to-office communication to manage construction & architectural projects. Simplifying communication like- Material requests Material inwarding notes Goods receiving notes Planned schedule Highlights, issues, RFIs, RFAs and more

Zylö Therapeutics

Series A in 2019
Zylö Therapeutics offers an innovative sustained-release drug-delivery system that was developed by Joel Friedman MD PhD, Adam Friedman MD FAAD, and Andrew Draganski PhD. The delivery system uses patented hydrogel-derived nanoparticles, called Nanopods, to deliver—in a sustained and controlled manner—notoriously hard-to-deliver therapeutic agents through topical administration. The company was founded in 2017 and is based in Greenville, South Carolina.

DetraPel

Seed Round in 2019
DetraPel is a cleantech advanced materials company that specializes in synthesizing and manufacturing PFAS-Free Protective Coatings.

CytoAgents

Angel Round in 2019
CytoAgents is a clinical stage biotechnology company focused on the development of innovative pharmaceutical products for the treatment of life-threatening symptoms associated with Cytokine Release Syndrome (CRS), an overreaction of the immune system causing systemic inflammation also known as cytokine storm.

Tunnel

Seed Round in 2018
Tunnel is a fintech company that offers real-time cross-currency payments services. The company utilizes a Distributed Ledger Technology (DLT) to offer no transaction fee processing. It also provides payment rails, APIs, and mobile apps. Frank Makrides, Mariana Jbantova Svirchuk, and Neil Ratna established Tunnel in Boston, Massachusetts in 2018.

RevBio

Convertible Note in 2018
RevBio is commercializing an injectable, self-setting, osteoconductive bone adhesive biomaterial that can bond bone to bone and bone to metal in a wet field environment. The company's showcase product, Tetranite, is being reviewed by the FDA for a growing body of applications including oral, craniofacial, orthopedic, and neurosurgical indications. Over time, this synthetic adhesive biodegrades and is replaced by new bone. This unique material will reduce the duration and complexity of medical procedures, allow for more minimally invasive surgeries, and will improve patient outcomes by reducing recovery time and the overall cost of care.

Anubis Bio

Angel Round in 2018
Anubis Bio has USPTO patented Microbiome-Cleanser (TM) natural food platform that quickly resolves GI-distress-diarrhea in animals starting with dogs (www.doggystat.com). Two major B2B distribution partnerships signed in 2021.

KnipBio

Series B in 2018
KnipBio is a biotechnology company that develops responsible and sustainable commercial feed solutions for the aquaculture industry. It is committed to solving real-world challenges by working with global corporations. Its game-changing single-cell protein combines the attributes of premium, protein-packed fishmeal, and carotenoids into a single effective and affordable fishmeal replacement -- KnipBio Meal (KBM). KBM is a transformative breakthrough in the future of aquaculture feed. It was founded in 2013 and is based in Lowell, Massachusetts.

Candidly

Seed Round in 2018
Candidly is an AI-driven student debt and savings optimization platform. It offers individuals and families through every step of the planning, borrowing, and repayment experience.

BrandVerge

Angel Round in 2017
BrandVerge is a marketplace + workflow tool that makes it easy for advertisers to plan premium media partnerships at scale. Our platform takes brands from discovery to recommendation in a few easy steps, ultimately bringing relevant buyers to the media companies on BrandVerge! We are the only two-sided solution in the space that proactively increases visibility and new business for our publisher partners, while simultaneously increasing efficiency for our advertisers by 80+%.

DeepLook

Angel Round in 2017
DeepLook is a point-and-click tool that integrates mammography workstations to fit with the radiologist’s workflow.

Astrocyte Pharmaceuticals

Seed Round in 2017
Astrocyte Pharmaceuticals is a drug development company that helps in the recovery and well-being of brain injury patients. The company is committed to proving the neuroprotective benefits of selective astrocyte activation and advancing breakthrough therapeutic agents for treating brain injury resulting from stroke, TBI, concussion, and neurodegenerative disorders such as Alzheimer’s disease.

Quthero

Angel Round in 2017
Quthero is engaged in the process of developing a gel for post-surgical scarring prevention. They created a gel that can restore the moisture and mechanical properties of the wound to support healing.

Astrocyte Pharmaceuticals

Seed Round in 2017
Astrocyte Pharmaceuticals is a drug development company that helps in the recovery and well-being of brain injury patients. The company is committed to proving the neuroprotective benefits of selective astrocyte activation and advancing breakthrough therapeutic agents for treating brain injury resulting from stroke, TBI, concussion, and neurodegenerative disorders such as Alzheimer’s disease.

PlaceMe

Pre Seed Round in 2017
PlaceMe simplifies the rental market for young professionals and grad students by leasing all-inclusive fully-furnished bedrooms at a flat monthly rent with flexible lease terms.

Xylyx

Angel Round in 2016
Xylyx Bio creates effective science-based solutions for the benefit of human life and health. Xylyx Bio is a biomaterials pioneer, providing customers with products for research, clinical, and commercial applications. The company's solutions provide scientists engaged in pharmaceutical development, cell biology research, and regenerative medicine with the complete spectrum of components from the natural cell microenvironment required for precise and actionable results.

GoodTwo

Angel Round in 2016
GoodTwo is a platform that allows fundraisers to run campaigns using group buying deals to generate donations. Fundraisers of any size, from individuals raising money for a cause to school/community groups to large nonprofits, can set up a free fundraising page and select up to three deals at local and national brands. These deals, negotiated in advance by GoodTwo, are the same as those you'd find on group buying sites such as Groupon, LivingSocial, and GoodTwo's parent company, CoupMe (a New England-based deal a day site). The fundraisers then uses tools available through GoodTwo as well as their own donor list to let potential donors know about the fundraiser. For every deal sold, half the profits that GoodTwo receives are given as a donation. (The donation for each deal is clearly spelled out in the buying process.) All fulfillment, customer service, deal negotiation, etc. is handled by GoodTwo. The fundraiser simply extends the offers to its database.

Neuraly

Angel Round in 2016
Neuraly, a startup biotech company, was formed in 2016 following foundational research by world class neuroscientists led by Ted Dawson, M.D., Ph.D., Leonard and Madlyn Abramson Professor in Neurodegenerative Diseases and Director of the Institute for Cell Engineering at the Johns Hopkins School of Medicine. Following the acquisition of exclusive licenses to patents covering the composition of matter and methods of use, research supporting the development of NLY01 was recently published in Nature Medicine1. These data demonstrated the critical role of the glial compartment of the neural tissue in the pathogenesis of neurodegenerative diseases such as Parkinson's and Alzheimer's diseases.

Gramify

Angel Round in 2016
Gramify is personalized audio greetings that feature the voice of celebrities and fictional characters. These are emotionally-engaging alternatives to print cards and ecards. They are bought online and delivered either through a phone call or through Facebook. They started signing licenses and are negotiating with major brands. The best part is the team which include licensing heavyweights who have done hundreds of deals.

NextShift Robotics

Angel Round in 2016
NextShift Robotics is a Massachusetts-based company that offers an e-commerce order fulfillment and manufacturing solution using autonomous mobile robots developed specifically to address the needs of your accelerated order fulfillment while extending the capacity of your existing warehouse. NextShift’s competitive advantage is a unique, more efficient workflow. Our system offers rapid deployment, low maintenance, and is built for demanding warehouse conditions. Our team contains experts in material handling, robotics, and warehouse automation.

Landsdowne

Angel Round in 2016
Landsdowne is a developer of battery technology. They provide products that include materials for injury prevention products. For international businesses looking for a turnkey, affordable solution to the worsening button battery health crisis, Landsdowne Labs is commercializing battery technology.

Pyramid Biosciences

Angel Round in 2016
Pyramid Biosciences is dedicated to discovering and developing targeted therapeutics for a wide range of disorders that are regulated by the tropomyosin receptor kinase (TRK) family. By precisely and selectively modulating the actions of these fundamental cell surface receptors, we can control the key signaling pathways responsible for a patient’s disease, condition, or symptoms.

Fynalist

Angel Round in 2016
Fynalist is a platform for corporate recruiters and talent acquisition professionals to find qualified and active candidates.

Lumo

Angel Round in 2016
At lumo,They’re obsessed with making air travel smarter. They predict flight delays months, weeks, hours ahead of time, making planning easier and flight changes less stressful.

Xeno Biosciences

Angel Round in 2015
Xeno Biosciences operates as a biopharmaceutical company pioneering a novel class of therapeutics to address large unmet needs in metabolic diseases. Lead program, XEN-101, is a first-in-class, oral formulation designed to shift the gut microbiome to the weight-loss associated state induced by Roux-en-Y Gastric Bypass (RYGB) surgery. It was founded in 2015 and is headquartered in Somerville, Massachusetts.

Green Pinata, LLC

Angel Round in 2015
Green Pinata is an online toy rental subscription service platform that offers educational and fun toys for young children to learn and play. They also provide toxin-free educational toys for kids and young children.

Archer Roose

Angel Round in 2015
Archer Roose is a clean wine brand cultivating a new generation of consumers through a global portfolio and a tech platform making wine more accessible than ever before.

Platelet BioGenesis

Angel Round in 2015
Platelet BioGenesis specializes in the fields of biotechnology, platelets, and drug discovery. They discover a new category in therapeutics. The company is developing technology to produce donor-independent human platelets from human induced pluripotent stem cells.

RevBio

Angel Round in 2014
RevBio is commercializing an injectable, self-setting, osteoconductive bone adhesive biomaterial that can bond bone to bone and bone to metal in a wet field environment. The company's showcase product, Tetranite, is being reviewed by the FDA for a growing body of applications including oral, craniofacial, orthopedic, and neurosurgical indications. Over time, this synthetic adhesive biodegrades and is replaced by new bone. This unique material will reduce the duration and complexity of medical procedures, allow for more minimally invasive surgeries, and will improve patient outcomes by reducing recovery time and the overall cost of care.

Medumo

Angel Round in 2014
Medumo is a healthcare statrtup that helps healthcare organizations deliver the right instructions to the right patients at the right time using automated SMS and email. The company combines technologies in mobile communication and artificial intelligence to equip providers with the capability to engage their patients more without more time or money. It also empowers patients by giving them the right information at precisely the time of need. Its ultimate vision is a more transparent, knowledgeable and healthy world.

Siamab Therapeutics

Series B in 2014
Siamab Therapeutics is a biopharmaceutical company that develops therapies targeting abnormal carbohydrates found only on cancer cells. It has developed a platform of technologies that enables the discovery and development of anti-TACA therapeutic antibodies. The company’s core technologies were licensed from the laboratory of Ajit Varki, a professional in glycobiology and sialic-acid biochemistry. It has brought together a team of scientists and advisors in oncology, glycoimmunology, and antibody engineering to support its anti-TACA antibody discovery and development programs. Siamab Therapeutics was founded in 2006 and is headquartered in Newton, M.A.

Sialix Cancer Research

Series B in 2014
Sialix Cancer Research provides cancer susceptibility antibodies and cancer-associated nucleoprotein antibodies for breast cancer. They also offer laser-based photodynamic endoscopic diagnosis using 5-aminolevulinic acid for early gastric adenocarcinoma and gastric adenoma.

Ionica Sciences

Angel Round in 2014
Ionica Sciences™ is utilizing a new technology platform to meet urgent needs in clinical diagnostics.The ability to rapidly and accurately identify the presence of diseases would provide clinicians with the ability to reduce suffering of their patients, the use of antibiotics, and healthcare costs that result from mis- or missed diagnoses.

Simple Science

Angel Round in 2014
Simple Science provides anti-microbial products designed to lead a healthy life. They help people lead healthier lives through healthier products, like their antimicrobial skin therapies that contain no steroids or their household cleaners that contain no harmful chemicals.

CleanFiber

Seed Round in 2013
CleanFiber makes high-performance, carbon-negative building insulation from recycled corrugated cardboard. The company is fully commercial and rapidly scaling up production from its first facility in Buffalo, NY.

KnipBio

Angel Round in 2013
KnipBio is a biotechnology company that develops responsible and sustainable commercial feed solutions for the aquaculture industry. It is committed to solving real-world challenges by working with global corporations. Its game-changing single-cell protein combines the attributes of premium, protein-packed fishmeal, and carotenoids into a single effective and affordable fishmeal replacement -- KnipBio Meal (KBM). KBM is a transformative breakthrough in the future of aquaculture feed. It was founded in 2013 and is based in Lowell, Massachusetts.

Siamab Therapeutics

Series B in 2013
Siamab Therapeutics is a biopharmaceutical company that develops therapies targeting abnormal carbohydrates found only on cancer cells. It has developed a platform of technologies that enables the discovery and development of anti-TACA therapeutic antibodies. The company’s core technologies were licensed from the laboratory of Ajit Varki, a professional in glycobiology and sialic-acid biochemistry. It has brought together a team of scientists and advisors in oncology, glycoimmunology, and antibody engineering to support its anti-TACA antibody discovery and development programs. Siamab Therapeutics was founded in 2006 and is headquartered in Newton, M.A.

Avaxia Biologics

Series B in 2013
Avaxia Biologics is a private, early-stage company developing orally-delivered antibody therapeutics using a proprietary antibody platform. The company is pursuing products for oral mucositis, inflammatory bowel disease, and diabetes, and obesity. Avaxia Biologics was founded in 2005 and headquartered in Lexington, Massachusetts.

Blurr

Seed Round in 2013
Conceal, share & reveal photos in a fresh new way on Blurr for iOS. BLURR combines three of the most popular social media activities together -- sharing, gamification and filters -- in a mobile app that places a value on a “like” to unlock content. * The originator uses filters to “blurr” a photo and then sets a certain number of likes required to unlock or “de-blurr” the photo. * Blurr participants can curate and collect content, create profiles, incentivize your existing audiences on any social media platform to engage on BLURR. * Blurr leaderboard will focus on what’s trending within the app, highlighting the most popular photos on BLURR in real time.

Premama

Angel Round in 2013
Premama® is the doctor-recommended, daily prenatal multivitamin in powder form. Easy to mix in a cold beverage, yogurt or smoothie. Premama helps improve the nutritional status of expectant women with DHA, folic acid, B6 for nausea relief and so much more! Find Premama Complete at Target, and Essentials and Plus formulas at Amazon, Buy Buy Baby and specialty vitamin and health food stores.

Siva Therapeutics

Venture Round in 2012
Siva Therapeutics develops cancer therapies that improve patient outcomes. They develop safe, minimally-invasive, practical, and cost-effective medical device treatments for cancer using proprietary technologies. The company's therapy generates therapeutic heat within solid tumors using gold nanorods and an infrared light device which is more selective than chemotherapy, less destructive than radiation, and without the risks of surgery.

Avaxia Biologics

Series B in 2012
Avaxia Biologics is a private, early-stage company developing orally-delivered antibody therapeutics using a proprietary antibody platform. The company is pursuing products for oral mucositis, inflammatory bowel disease, and diabetes, and obesity. Avaxia Biologics was founded in 2005 and headquartered in Lexington, Massachusetts.

Siva Therapeutics

Angel Round in 2012
Siva Therapeutics develops cancer therapies that improve patient outcomes. They develop safe, minimally-invasive, practical, and cost-effective medical device treatments for cancer using proprietary technologies. The company's therapy generates therapeutic heat within solid tumors using gold nanorods and an infrared light device which is more selective than chemotherapy, less destructive than radiation, and without the risks of surgery.

3Derm Systems

Angel Round in 2012
3Derm is a cost-effective, skin imaging system that allows non-dermatologists to take clinical-quality 3D skin images remotely. Two million Americans develop skin cancer every year. With 3Derm, dermatologists can review images taken at medical kiosks and other referral sites to efficiently monitor high volumes of patients’ lesions while reserving in-office appointment times for those patients whose images indicate a more alarming condition. 3Derm cuts down on wait times reduces healthcare spending and save lives. Two million Americans develop skin cancer every year. Patients currently monitor their skin through routine dermatology appointments, which are scheduled as frequently as six times per year for high-risk cases. These are both expensive and inconvenient. 3Derm Systems is developing a low-cost skin monitoring solution that allows patients to take clinical-quality 3D images from the comfort of their own homes. Dermatologists can use the uploaded images to efficiently monitor high volumes of patients' lesions while reserving in-clinic appointment times for patients whose images indicate a more alarming condition. 3Derm aims to revolutionize the field of teledermatology by providing greater access to dermatological care. Some patients use handheld digital cameras or apps to take and send images via teledermatology. 3Derm allows patients to keep their local dermatologist instead of using a telemedicine service and uses clinical quality features that ensure every image maximizes diagnostic usefulness for both the patient and the physician.

Newfield Design

Series A in 2012
Newfield Design is a Maine, US based company that designs, develops and manufactures communications systems infrastructure. The founders have decades of experience in successful communications system design, development, deployment and management, particularly with Public Safety, Commercial/SMR and Critical Infrastructure communications systems.

Avaxia Biologics

Series A in 2012
Avaxia Biologics is a private, early-stage company developing orally-delivered antibody therapeutics using a proprietary antibody platform. The company is pursuing products for oral mucositis, inflammatory bowel disease, and diabetes, and obesity. Avaxia Biologics was founded in 2005 and headquartered in Lexington, Massachusetts.

Mosaic Storage Systems

Seed Round in 2012
Mosaic Storage Systems is a provider of digital asset storage services used to help professional photographers to store their photographs. Its digital asset storage services take digital copies of photographs, stores them on its servers, and make them accessible via the internet that enables users to store and share photographs securely. It was founded in 2011 and is based in Nashua, New Hampshire.

ImmuneXcite

Series A in 2012
ImmuneXcite has developed a proprietary platform technology for enhancing the efficacy of therapeutic monoclonal antibodies for oncological and infectious disease targets. ImmuneXcite was founded based on research originating from the Whitehead Institute at MIT, where a unique carbohydrate was shown to activate neutrophils. Chemically linking the carbohydrate to monoclonal antibodies to improve their effector function is a bold concept that has been supported by the Massachusetts Technology Transfer Center, Deshpande Center for Technological Innovation at the Massachusetts Institute of Technology (MIT), the Department of Defense, Massachusetts Life Science Center, National Cancer Institute, and private investor. Immunexcite, Inc., a biopharmaceutical company, develops monoclonal antibodies for cancer. The company develops monoclonal antibodies by employing its mAbXcite, an immunotherapy platform technology that targets cancer cells for destruction by engaging neutrophils. Immunexcite, Inc. was founded in 2007 and is based in Lexington, Massachusetts.

Amsel Medical Corp

Angel Round in 2012
Amsel Medical is a medical device company that develops mechanical surgical clamping technology for surgical and interventional procedures. The SCureClamp with Interdigitation Occlusion Technology (iDOTTM) from Amsel Medical is designed to easily and securely close vessels such as veins, arteries, and tubular structures. The anchoring feature of the SCureClamp keeps the implant in place and prevents slippage. Grasping enables doctors to occlude vessels of various sizes, types, and wall thicknesses.

Windgap Medical

Angel Round in 2011
WindGap Medical is a biotech company that manufactures medical devices used to treat patients with severe allergies. The company develops auto-injectors that are filled with heat-stable epinephrine that enable physicians to inject it into a patient suffering from anaphylaxis due to an acute allergy attack. The company was established in 2011 and is headquartered in Somerville, Massachusetts.

Avaxia Biologics

Venture Round in 2011
Avaxia Biologics is a private, early-stage company developing orally-delivered antibody therapeutics using a proprietary antibody platform. The company is pursuing products for oral mucositis, inflammatory bowel disease, and diabetes, and obesity. Avaxia Biologics was founded in 2005 and headquartered in Lexington, Massachusetts.

Newfield Design

Seed Round in 2011
Newfield Design is a Maine, US based company that designs, develops and manufactures communications systems infrastructure. The founders have decades of experience in successful communications system design, development, deployment and management, particularly with Public Safety, Commercial/SMR and Critical Infrastructure communications systems.

Vizibility

Series A in 2011
Vizibility helps people package and promote their online presence with a powerful Mobile Business Card. Build trust and credibility quickly when you make an accurate, powerful and lasting impression. Your mobile business card is like a personalized, mobile-friendly website with key content about you and your organization. It's instantly accessible from any smartphone without an app. And it's a snap to share using QR codes and Microsoft Tag barcodes, NFC mobile wallet cards, Apple Passbook and special buttons and links. Vizibility's mobile identity management platform is integrated and resold by printers and web-to-print vendors which are seeking to offer valuable new features, generate new revenue streams and differentiate themselves from competitors. U.S. Patents 7,831,609, 7,987,173, 8,095,534, 8,271,650, 8,275,837 and 8,280,879. Other patents pending.

Testive

Angel Round in 2011
Testive is at the forefront of developing education products that blend teachers and technology. Their private tutoring products use technology to deliver one-on-one instruction at lower cost than any other private instruction model. Over 30K students and teachers have used their test preparation technologies to help them to help them on their preparation journey. Their core platform and approach was developed at MIT to speed up the learning feedback cycle. Testive is based in Cambridge, MA with offices in Durham, NC and is an alumnus of the TechStars Boston accelerator program.

Kalion

Angel Round in 2011
Kalion is an early stage industrial biotech company that will transform the traditional chemical industry by providing low-cost access to glucaric acid and S-3-hydroxybutyrolactone (3-HBL) using traditional, green, fermentation technology. Glucaric acid and 3-HBL were identified as “Top Value Added Chemicals from Biomass” and multi-billion dollar markets for use of the two chemicals are limited by cost and availability (2004 DOE report).

ReDigi

Venture Round in 2011
ReDigi is the online marketplace for pre-owned digital music and the only Cloud service that verifies whether each music file uploaded for storage was legally acquired from an eligible source. ReDigi's patent pending methods are revolutionary. In addition to the highly sophisticated Verification Engine, the Atomic Cloud transfer system enables the transfer of a digital music file between buyer and seller without copying or file sharing. In addition to these technological breakthroughs, ReDigi supports artists directly through a unique platform that, for the first time in the secondhand music market, grants generous payments from each track sold (and resold) directly to the artist who created it.

Pixability

Angel Round in 2011
Pixability is a data and technology company that enables brands and their agencies to maximize the value of video advertising across YouTube, YouTube on TV, and other CTV inventory including Roku, Amazon Fire, and Hulu. The company's patented technology platform, PixabilityONE, enables advertisers to ensure brand suitability, maximize the return on their video ad spend, and garner insights not available elsewhere in the industry. Pixability technology is leveraged globally by WPP/GroupM, IPG, Dentsu, Publicis, OMG and Independent agencies as well as leading brands across most verticals. The company is the only YouTube Measurement Partner certified for Brand Suitability & Contextual Targeting as well as Content Insights and is also partnered with measurement companies including DoubleVerify, Oracle Data Cloud, Nielsen, Comscore, and Integral Ad Science.

Bliss Health

Seed Round in 2011
Bliss Health offers care management services through a network of integrated medical, nursing, and home care services.

1908 Brands

Angel Round in 2011
1908 Brands manufactures, manages, and markets natural product brands such as Boulder Clean, CompoKeeper, thrive TRIBE, Fruitivity Snacks, Schultz’s, Pasta Jay’s, and Yummari. The values of the company are trust, adaptiveness, passion, knowledge, efficiency, and collaborative. 1908 Brands was founded in 2010 by Steve Savage. The company is based in the United States.

scrible

Angel Round in 2011
scrible provides a Web-based service enabling people to highlight and annotate web pages and easily save, share, organize and collaborate on Internet-based research. scrible's goal is to revolutionize how the world works online by transforming Web-based research. The Internet has become a widely used resource for all sorts of research (medical information, school papers, analyst reports, job hunting, etc.) at work, school and home. Yet, most of the world still uses outdated methods to annotate, organize and share their research (printing to annotate by hand, copying/pasting into a document, etc.). scrible aims to bring Internet-based research into the Internet Era by enabling people to annotate web pages directly in the browser and then manage that research online. scrible's service is useful for anyone researching anything on the Web, but particularly valuable for those who work in environments where the efficient flow and analysis of information is vital to daily work. scrible's Team is solving hard problems in information management that people feel everyday due to the limits of Desktop Era systems. Their mission is to help humanity work smarter in the Internet Age.

Athletic Standard

Seed Round in 2011
Athletic Standard connects college coaches to potential athletes at a fraction of the cost of current recruiting applications and yes, their is a lot of deep tech that will be releasing this summer. We will redefine sport economics ATHLETIC STANDARD can help simplify the college recruiting process by testing and registering potential college athletes for free onto a secure database that can be seen by college coaches from all over the country. Coaches will have a certified athletic test score as well as a complete athletic profile including academic records, game video, and more

CoolChip Technologies

Angel Round in 2011
CoolChip specializes in Kinetic Cooling, a category based on disruptive technology transforming electronics cooling that is transforming the electronics cooling industry. Solutions Powered by Kinetic CoolingTM offer unprecedented performance across acoustics, form factor, and cooling. By partnering with CoolChip, consumer electronics and enterprise manufacturers have the opportunity to unleash innovation and deliver next-generation products for their customers. CoolChip was founded by MIT engineers in 2011 and is the exclusive provider of Kinetic CoolingTM technology. The company holds an extensive intellectual property portfolio and is based in Boston, MA.

Vizibility

Seed Round in 2010
Vizibility helps people package and promote their online presence with a powerful Mobile Business Card. Build trust and credibility quickly when you make an accurate, powerful and lasting impression. Your mobile business card is like a personalized, mobile-friendly website with key content about you and your organization. It's instantly accessible from any smartphone without an app. And it's a snap to share using QR codes and Microsoft Tag barcodes, NFC mobile wallet cards, Apple Passbook and special buttons and links. Vizibility's mobile identity management platform is integrated and resold by printers and web-to-print vendors which are seeking to offer valuable new features, generate new revenue streams and differentiate themselves from competitors. U.S. Patents 7,831,609, 7,987,173, 8,095,534, 8,271,650, 8,275,837 and 8,280,879. Other patents pending.

ConveyIQ

Angel Round in 2010
ConveyIQ provides an intelligent candidate engagement platform. Its platform features an all-in-one bespoke communication framework for the entire candidate journey. ConveyIQ delivers personalized applicant communication that companies need to ensure a remarkable candidate journey.

RedDress

Angel Round in 2010
RedDress is a medical device company that developed a wound care product that helps the human body on the wound healing process. It specializes in wound care, wound healing, tissue repair, regenerative medicine, chronic ulcers, diabetic and foot ulcers. The company was founded in 2009 and headquartered in Tel Aviv, Israel.

Respiratory Motion

Angel Round in 2010
Respiratory Motion has a wide variety of patient populations and environments to assess respiratory function and provide early warning of respiratory collapse. It is a commercial-stage medical device company that specializes in the fields of medical devices, clinical evaluation and testing, manufacturing, and respiratory monitoring.

SmartCells

Series D in 2010
SmartCells, Inc. designs and develops insulin products. It offers SmartInsulin, a self regulating injectable formulation for treating diabetes. The company's polymer-based dosing technology is used for various applications, such as fertility, thyroid, and growth hormone deficiencies; treatments with poor compliance or therapeutic window issues, such as oncology; and drug-device combinations. SmartCells, Inc. was founded in 2003 and is based in Beverly, Massachusetts.

Lessac Technologies

Angel Round in 2010
Lessac Technologies Automated Narrator Demonstrates Fully Automatic Expressive Text-to-Speech.

Incentive Targeting

Series A in 2010
Incentive Targeting partners with retail chains to provide a targeted marketing service to manufacturers of grocery and consumer products. Using its service, manufacturers market directly to individual shoppers across our entire retail network–based on each person's detailed purchase history. Promotions are delivered via any available distribution channels, such as email, direct mail, or register tape.

ZetrOZ

Angel Round in 2010
ZetrOZ is revolutionizing the ultrasound industry by introducing proprietary generator technology that is more efficient, more portable, and more economically viable than any ultrasound generator presently available.

Corbus Pharmaceuticals

Angel Round in 2010
Corbus Pharmaceuticals Holdings, Inc. is a Phase 3 clinical-stage pharmaceutical company focused on the development and commercialization of novel therapeutics to treat inflammatory and fibrotic diseases by leveraging its pipeline of endocannabinoid system-targeting synthetic drug candidates. The Company's lead product candidate, lenabasum, is a novel, synthetic, oral, selective cannabinoid receptor type 2 (CB2) agonist designed to resolve chronic inflammation and fibrotic processes. Lenabasum is currently being evaluated in systemic sclerosis, cystic fibrosis, dermatomyositis, and systemic lupus erythematosus. Corbus is also developing a pipeline of drug candidates from more than 600 novel compounds targeting the endocannabinoid system. The pipeline includes CRB-4001, a 2nd generation, peripherally-restricted, selective cannabinoid receptor type 1 (CB1) inverse agonist. Potential indications for CRB-4001 include NASH, among others. Corbus plans to start a Phase 1 study of CRB-4001 in 2019, intended to be followed by a National Institutes of Health (NIH)-funded proof-of-concept Phase 2 study.

Myomo

Venture Round in 2009
Myomo, a medical technology company, develops Myoelectric prosthetic technology to powered bracing devices that restore an individual’s mobility. It offers Myomo mPower 1000, a portable lightweight functional arm brace for use in the home and in clinical settings, which restores movement to a weakened arm as a result of neuromuscular damage caused or due to brain injury, including stroke, spinal cord injury, multiple sclerosis, cerebral palsy, muscular dystrophy, and traumatic brain injury. The company also provides PERL (Push, Eat, Reach, Lift) technique, a set of research-based treatment plans that integrate the mPower 1000 into functional repetitive task practice programs aiming to increase the functional activity; myGames, a virtual reality-based therapeutic training system to encourage brain-injured patients with upper limb motor disorders to practice physical exercises; and myProgress, an Android-based connected health platform that tracks and measures progress while using the mPower 1000. Its mobility system is designed to enable individuals to self-initiate and control the movement of partially paralyzed limbs using their own muscle signals. The company serves medical professionals, patients, and caregivers in the United States. Myomo, Inc. was formerly known as Active Joint Brace. The company was founded in 2004 and is based in Cambridge, Massachusetts.

Daktari Diagnostics

Series A in 2009
Daktari Diagnostics was founded to create products that address the most pressing challenges in global health. These problems include not only better diagnosis of disease, but also the communication of data throughout the healthcare system. We are committed to delivering critical diagnostic test results to clinicians and patients across the globe. Our team of engineers, scientists, physicians, and global health experts is uniquely dedicated to making high-performance products specifically designed for resource-poor markets. We recognize that information can only be useful if it can move. Daktari’s products are connected in the field, allowing clinical, quality, and performance data to flow where it needs to go. We strive to provide quality products at an affordable price, and to support our products when used by anyone, anywhere in the world. We strive to treat our customers, our partners, and our colleagues with kindness, as equals, and to be a positive force in our communities and in the world.

AisleBuyer

Angel Round in 2009
AisleBuyer is a mobile shopping platform that dramatically improves the in-store retail shopping experience by leveraging SmartPhone technology to unite the best features of both "bricks" and "clicks" retailing. Our virtual shopping assistant, "location aware" digital circular, and first ever mobile self-checkout system provides retailers with an end-to-end solution designed to increase sales, reduce costs and gain unprecedented analytical insight into in-store shopping behavior. A simple product scan provides consumers with valuable product info, targeted offers and a mobile self-checkout option -- meaning they will never have to wait in line again.

Immusoft

Angel Round in 2009
Immusoft Corporation is a biotechnology company based in Seattle, Washington, focused on developing autologous cell therapies for various human diseases through its proprietary Immune System Programming (ISP) technology. Founded in 2009, the company modifies a patient's immune cells, specifically B cells, to create miniature drug factories that produce gene-encoded medicines, or biologics. By reprogramming these cells, Immusoft's technology enables the in vivo delivery of therapeutics that can replace missing or defective enzymes and proteins. The core ISP technology was initially developed at the California Institute of Technology and is exclusively licensed to Immusoft. This innovative approach aims to improve treatments for rare and infectious diseases by harnessing the body's own immune system.

JB Therapeutics

Angel Round in 2009
JB Therapeutics is a clinical stage biopharmaceutical company developing the first new class of analgesic agents in two decades. Their lead compound, JBT-101, is a potent CB1 and CB2 agonist with demonstrated efficacy in several animal models of pain and inflammation. It has also completed a Phase II clinical study in chronic refractory neuropathic pain. JBT-101 is currently being developed as a potential disease modifying treatment for osteoarthritis. JBT-101 also represents a platform for combination with other anti-inflammatory and analgesic agents as well as various drug delivery strategies including ointment and gels, topical patches, and timed release formulations.

ImageRights

Angel Round in 2009
ImageRights International provides intelligent image search and copyright enforcement services to photo agencies and professional photographers worldwide to ensure that their intellectual property rights are protected and that they are compensated for the unauthorized use of their copyrighted works. ImageRights, the only company to have fully automated copyright registration with the US Copyright Office, has made copyright enforcement a truly integrated component of its clients' daily workflow.

CollegeWikis

Seed Round in 2008
CollegeWikis.com is the leading group messaging and information platform for students by students. Since its launch last year, CollegeWikis has become the group messaging platform of choice for over 50,000 students in more than 200 colleges, with over 600,000 topics. On CollegeWikis, students can join groups for their school, courses, dorms, and more; then send and follow group messages to peers. Those messages then become wiki-editable pages on the site, providing information that is always accurate and searchable by others. The original idea for the site came from Founder Joe DiPasquale's experience in business school. He told us: "We had an email list for our class year, through which hundreds of messages were sent per week. But students faced two problems: the absence of group lists that we really wanted, like for our dorm or courses; and all the great content sent out over the list was soon buried in people’s email inboxes. CollegeWikis not only provides these groups but also captures their content."

WebNotes

Angel Round in 2008
WebNotes helps people manage the deluge of online content they sift through every day by providing users with a virtual highlighter and sticky note tool that can be used to make annotations directly on any web page. These tools eliminate the need to repeatedly copy & paste information into a word document or e-mail, or sort through hundreds of bookmarks. Users' annotations are automatically saved to their WebNotes accounts for later reference, and can be searched, organized, and shared with others at any point in time.

BrandYourself

Seed Round in 2008
BrandYourself provides tools and services that help people look better online. This includes dealing with unwanted items – like an old divorce record or ill-advise tweet – as well as helping promote positive items that benefit someones career. In 2012, BrandYourself launched the first DIY online reputation management tool that walks users through the process of monitoring and improving their online presence. BrandYourself also offers reputation management services for individuals and businesses with a team of in-house content creators, web developers, social media managers, brand strategists and placement specialists. BrandYourself has secured over $6 million in venture capital, including investments from prominent angel investor Barney Pell (former Head Search Strategist at Microsoft & Architect at Bing), John Galanti (former President at Hudson Valley Datanet), Ryan Holmes (CEO & Co-founder at Hootsuite) as well as firms FF Angels, New Atlantic Ventures, Zelkova Ventures, and LeFrak Investments. BrandYourself has been recognized by the White House, named a "Best Entrepreneurial Company in America" by Entrepreneur Magazine, declared "Best Online Reputation Services for Individuals" by Business News Daily and appeared on ABC's Shark Tank, where they walked away from a $2 million offer - one of the highest offers in the show's history.

Emerginvest

Angel Round in 2008
Emerginvest is a website which helps investors research international stock markets, and then shows them how they can invest there. Emerginvest (a free service) is connecting investors to hundreds of thousands of undiscovered, international companies by providing data, research, and tools on 150+ world stock exchanges. Emerginvest lets anyone — even those who aren't familiar with world markets — find international stocks to invest in. After a few minutes of browsing, investors can find companies in emerging markets like China, or in frontier markets such as Vietnam or Botswana. Once a user finds an investment, Emerginvest can recommend all of the ways that an investor can own that particular stock—whether through suggesting local, English-speaking brokerages, or domestic vehicles such as mutual funds, ETFs, and ADRs.

Sifaka Productions LLC

Angel Round in 2008
Communication services, namely, providing online electronic bulletin boards and chat rooms in the field of general interest.

Tikatok

Angel Round in 2008
Tikatok is an on line community designed for children to write, illustrate and publish their own stories into real books. Tikatok was started by two moms that felt it is essential to give young children a place to channel their creativity and publish their work. For less than $20, children can self-publish their own paperback or hardcover book. With the help of "story sparks," a template-based system, children can easily start writing and illustrating stories. They can upload art directly to the site or mail it in. There are packages to schools and libraries for group orders. The site is very family centered, and has an awesome and well-thought-out privacy policy.

Incentive Targeting

Angel Round in 2007
Incentive Targeting partners with retail chains to provide a targeted marketing service to manufacturers of grocery and consumer products. Using its service, manufacturers market directly to individual shoppers across our entire retail network–based on each person's detailed purchase history. Promotions are delivered via any available distribution channels, such as email, direct mail, or register tape.

Oculis Labs

Seed Round in 2007
Oculis Labs is an advanced computer user security company that protects your screen from over-the-shoulder peepers. The technology uses eye tracking to calibrate the words on the computer screen associated directly with the user.

eSight

Angel Round in 2007
eSight is combining breakthrough advances in digital video capture and display with proprietary image processing algorithms to create evSpexâ„¢, a brand new way to help people challenged with low vision. evSpex enable people challenged with low vision to do more of the things they love, whenever and wherever they wish, without the limitations of today's non-portable assistive technology devices. They resemble sunglasses, but are so much more. Imagine the ability to zoom in/out, improve the brightness and contrast of whatever you are looking at, and even quickly store visual information for a closer look later. Currently in clinical evaluations, evSpex will be commercially available in 2010. Contact eSight today to learn more.

StylePath

Angel Round in 2007
StylePath is a shopping recommendation engine aimed at fashion, accessories, and home furnishings. It helps shoppers find items to their taste with a patented machine-learning algorithm, and also offers several other features, such as Window Shopping, which "feeds" shoppers a stream of products it thinks they'll find interesting. Other companies in this space include eBay, with its new Neighborhoods product, and fellow Boston-based start-up [StyleFeeder](http://www.crunchbase.com/organization/stylefeeder).

XCOR Aerospace

Angel Round in 2007
Founded in 1999, XCOR Aerospace is a small, privately-held California corporation. Their headquarters and development facilities are located at the Mojave Spaceport and Civilian Aerospace Test Center in Mojave, California. XCOR engages in research, development, and production of reusable rocket-powered, horizontal launch vehicles for suborbital, and ultimately, orbital travel.

Emovi

Angel Round in 2007
Emovi is a company offering medical solutions for joints assessments. Emovi is dedicated to providing the highest quality, most technologically advanced products for knee joint assessment to restore patient quality of life. they are a company of knowledgeable, dedicated team members committed to innovation in healthcare.

SmartCells

Series C in 2007
SmartCells, Inc. designs and develops insulin products. It offers SmartInsulin, a self regulating injectable formulation for treating diabetes. The company's polymer-based dosing technology is used for various applications, such as fertility, thyroid, and growth hormone deficiencies; treatments with poor compliance or therapeutic window issues, such as oncology; and drug-device combinations. SmartCells, Inc. was founded in 2003 and is based in Beverly, Massachusetts.

PawSpot

Angel Round in 2007
First, on PawSpot a human profile is included along with a pet profile, and users are encouraged to become “friends”. PawSpot seems to be aiming to provide much needed services to pet owners. In particular, arranging for friends to take care of each other’s pets while away on vacation, and finding local dog parks.

Wasabi

Angel Round in 2007
At Wasabi, they bring you food that embodies all of these things — simple, flavorful, and healthy. Modern Japanese cuisine isn’t complicated. They use fresh, simple ingredients that put a tingle on your tongue with their essential flavors — raw fish, zesty soy, and seaweed with attitude.

First Light Diagnostics

Angel Round in 2007
First Light Biosciences develops breakthrough automated medical diagnostic products for rapid, sensitive, and cost-effective detection of Healthcare-Associated Infections (HAI). The products address the need for cost-effective and accurate diagnostics to meet the explosive growth in testing. New testing is being driven by clinical studies showing that testing for infectious agents can help to dramatically lower the rate of hospital infections. Based on its proprietary MultiPath detection technology, First Light’s products combine the performance of the most advanced commercial laboratory tests with unprecedented affordability and ease-of-use.

The Canary System

Angel Round in 2006
The Canary System is a low-powered, laser-based instrument with an integrated intraoral camera that detects the presence of cracks and caries before they are large enough to appear on dental X-rays. The system also generates a patient report that contains an odontogram with Canary numbers, which are color-coded for the examined teeth, along with the dentist’s treatment recommendation. The Canary System’s reports can also be examined by the patient on The Canary Cloud. Launched in 2006, it is based in Toronto, O.N.

Cognoptix

Angel Round in 2006
Cognoptix is creating and developing an innovative, non-invasive eye test to assist in the early diagnosis of Alzheimer's Disease. Cognoptix's goal is to provide clinicians with a quick, predictive, reliable, inexpensive, and widely available test, enabling early diagnosis and treatment. The company was founded in 2001 and headquartered in Marlborough, Massachusetts.

Nomir Medical Technologies

Angel Round in 2006
Nomir Medical Technologies, Inc. is a medical device company with a pipeline of optical energy therapies.

Julianna Rae

Angel Round in 2006
Julianna Rae is a Provider of an online retail platform for women apparel. The company offers a range of clothes and intimate apparel to meet the fit and fashion needs of women and eco-conscious buyer.
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