Brightstone VIII

CryOSA, Inc., a medical device company, develops novel treatments for patients with sleep disordered breathing. It offers therapies for obstructive sleep apnea. CryOSA, Inc. was incorporated in 2014 and is based in Roseville, Minnesota.

Aria CV was founded in 2010 by Drs. John Scandurra and Karl Vollmers, formerly Fellows at the University of Minnesota’s Medical Devices Center. Aria has an exclusive license to certain patents from the University of Minnesota. Aria CV’s device has the potential to improve outcomes by reducing the workload on the right side of the heart.

Aria CV was founded in 2010 by Drs. John Scandurra and Karl Vollmers, formerly Fellows at the University of Minnesota’s Medical Devices Center. Aria has an exclusive license to certain patents from the University of Minnesota. Aria CV’s device has the potential to improve outcomes by reducing the workload on the right side of the heart.

StemoniX Inc. is a biotechnology company that specializes in stem cell technologies to enhance drug discovery and personalized medicine. Founded in 2014 and headquartered in Minneapolis, Minnesota, with an additional office in La Jolla, California, StemoniX provides innovative platforms for pharmaceutical and research institutions. Its flagship solution focuses on the three-dimensional printing of stem-cell-derived human tissue, enabling the creation of living cells in larger formats. This technology is particularly beneficial for studying various diseases, including heart disease, dementia, breast cancer, autism, and ALS. By advancing the production and application of stem cell technologies, StemoniX aims to meet the evolving needs of the healthcare sector.

Atavium, Inc. is a data management company based in Minneapolis, Minnesota, founded in 2015. It specializes in developing a cloud-based platform that organizes, automates, manages, and stores unstructured data sets, whether located in a data center or in the cloud. The platform is designed to simplify the handling of large data volumes, enabling enterprises to efficiently store, share, and synchronize their data securely. Atavium's technology allows users to automate the lifecycle of their data from the point of creation, addressing the challenges posed by the growing complexity of unstructured data. The company operates as a subsidiary of Quantum Corporation and is backed by a team of experienced professionals with a history of delivering impactful products in the storage and networking sectors.

StemoniX Inc. is a biotechnology company that specializes in stem cell technologies to enhance drug discovery and personalized medicine. Founded in 2014 and headquartered in Minneapolis, Minnesota, with an additional office in La Jolla, California, StemoniX provides innovative platforms for pharmaceutical and research institutions. Its flagship solution focuses on the three-dimensional printing of stem-cell-derived human tissue, enabling the creation of living cells in larger formats. This technology is particularly beneficial for studying various diseases, including heart disease, dementia, breast cancer, autism, and ALS. By advancing the production and application of stem cell technologies, StemoniX aims to meet the evolving needs of the healthcare sector.

In 2012, entrepreneurs Kian Salehi and Arash Allaei saw a need in their hometown community of Minneapolis for an easy, fast and affordable way to order delivery from all the wonderful restaurants in town. With years of restaurant experience under their belts, the pair decided to do something about it and Bite Squad was born. Bite Squad was created to be the last place you’ll ever have to go online to order cuisine for delivery or takeout. The company now partners with over 10,000 local restaurants in more than 400 cities nationwide, and employees over 5,000 drivers to deliver fresh food from the restaurant straight to the customer’s door—quickly and hassle-free!

Gravie, Inc. operates a health insurance platform that facilitates the comparison and purchase of health insurance plans for individuals, families, and employers. Founded in 2013 and headquartered in Minneapolis, Minnesota, the company provides a comprehensive solution for managing health insurance expenses through its mobile application and website. Gravie allows users to shop for insurance options available on government-run exchanges and directly from insurance companies. The platform also offers tools for employers to design custom benefits plans using a defined contribution approach, enabling them to set a fixed budget for employee health benefits. Additionally, Gravie provides year-round support, financial analysis, and services such as Gravie Care, which assists individuals in managing their healthcare expenses effectively.

Flipgrid, Inc. is a video-based discussion platform that allows users to record, share, and view short video demonstrations. Founded in 2014 and based in Minneapolis, Minnesota, Flipgrid serves a diverse range of sectors including education, business, government, and community organizations. The platform is utilized in over 40,000 classrooms and enterprises across 115 countries, facilitating active and social learning. It provides applications for iPad, Android, and iPhone, making it accessible for a wide audience. In June 2018, Flipgrid became a subsidiary of Microsoft Corporation, further expanding its reach and resources in the educational technology space.

HomeSpotter, LLC is a real estate technology company that develops mobile applications and web solutions aimed at providing real estate information and tools for agents, brokers, and multiple listing services across North America. Founded in 2009 and based in Minneapolis, Minnesota, HomeSpotter offers a mobile platform that enables over 250,000 agents to access property listings and communicate effectively with clients through built-in chat features. The platform utilizes real-time data from multiple listing services to help agents create and manage targeted advertising campaigns on social media, enhancing their marketing efforts. HomeSpotter was previously known as MobileRealtyApps.com, LLC before rebranding in January 2015.

Celcuity Inc. is a clinical-stage biotechnology company based in Minneapolis, Minnesota, focused on advancing cancer care through innovative diagnostic and therapeutic solutions. The company's CELsignia diagnostic platform analyzes living tumor cells from patients to identify the specific abnormal cellular processes driving their cancer, enabling personalized treatment options. Celcuity is developing the CELsignia HSF test to diagnose new sub-types of HER2-negative breast cancer, as well as the CELsignia MP test to identify multiple cancer sub-types across various types, including breast, lung, colon, ovarian, kidney, and bladder cancers. In addition to its diagnostic efforts, Celcuity is advancing a lead therapeutic candidate, gedatolisib, a potent pan-PI3K and mTOR inhibitor, which is currently being evaluated in a Phase 3 clinical trial for patients with HR+/HER2- advanced breast cancer. Founded in 2011, Celcuity aims to transform the treatment landscape for patients with cancer by providing targeted therapies tailored to their unique disease profiles.

HomeSpotter, LLC is a real estate technology company that develops mobile applications and web solutions aimed at providing real estate information and tools for agents, brokers, and multiple listing services across North America. Founded in 2009 and based in Minneapolis, Minnesota, HomeSpotter offers a mobile platform that enables over 250,000 agents to access property listings and communicate effectively with clients through built-in chat features. The platform utilizes real-time data from multiple listing services to help agents create and manage targeted advertising campaigns on social media, enhancing their marketing efforts. HomeSpotter was previously known as MobileRealtyApps.com, LLC before rebranding in January 2015.

Miromatrix Medical Inc. is a biotechnology company focused on developing biological human organs and organ-derived products to address the shortage of transplantable organs. Utilizing patented perfusion decellularization and recellularization technology, the company creates fully biological organs and acellular products. Its offerings include MIROMESH, a non-crosslinked acellular surgical mesh designed for soft tissue repair in plastic and reconstructive surgeries, and various non-crosslinked acellular wound matrixes, such as MIRODERM, for managing different types of wounds, including chronic ulcers and surgical sites. Founded in 2009 and based in Eden Prairie, Minnesota, Miromatrix Medical serves a global customer base with innovative solutions for organ transplantation and advanced wound care.

Disc Dynamics is a healthcare company. They design and develop medical products. The Company offers surgical alternatives for the treatment of lower back problems and disc diseases. It offers DASCOR Disc arthroplasty system, a catheter-based minimally invasive nucleus replacement technology for the treatment of degenerated lumbar discs. Disc Dynamics was founded by Jeffrey Felt in 2000 and is headquartered in Eden Prairie, Minnesota.

Prolatus licenses software that allows customers to send large graphic files through regular telephone lines. The company targets pre-press, printing and content provider companies as its customers. See complete list.