Epimède

ImCyse SA is a clinical-stage biopharmaceutical company based in Liège, Belgium, that specializes in developing active immunotherapies aimed at treating and preventing severe chronic autoimmune diseases linked to immune system disruptions. Founded in 2010, ImCyse utilizes a unique technology platform that focuses on the administration of Imotopes™, specifically modified peptides that generate cytolytic CD4 T-cells. These T-cells selectively eliminate antigen-presenting cells and autoantigen-specific lymphocytes, targeting the underlying causes of diseases like type 1 diabetes and multiple sclerosis. ImCyse's innovative approach not only aims to provide therapeutic alternatives where none exist but also seeks to cure patients without compromising their immune defenses. The company has demonstrated proof of concept across several indications and has successfully completed its first clinical trial for type 1 diabetes, yielding promising results while developing additional Imotopes™ for various autoimmune conditions.

Endo Tools Therapeutics S.A. is a medical device company based in Gosselies, Belgium, founded in 2008. The company specializes in the development and manufacture of innovative therapeutic devices for gastroenterologists, focusing on flexible endoscopic interventions. Endo Tools Therapeutics is currently working on a catheter that will enhance therapeutic capabilities in interventional gastroenterology by adding therapeutic channels and degrees of freedom. The company's products aim to address conditions such as obesity, digestive tract tumors, and diabetes, enabling efficient surgical endoscopy through advanced techniques like flexible endoscopic suturing and tissue apposition. Additionally, the company has developed the ENDOMINA platform, which provides gastroenterologists with an open system for performing therapeutic procedures.

Endo Tools Therapeutics S.A. is a medical device company based in Gosselies, Belgium, founded in 2008. The company specializes in the development and manufacture of innovative therapeutic devices for gastroenterologists, focusing on flexible endoscopic interventions. Endo Tools Therapeutics is currently working on a catheter that will enhance therapeutic capabilities in interventional gastroenterology by adding therapeutic channels and degrees of freedom. The company's products aim to address conditions such as obesity, digestive tract tumors, and diabetes, enabling efficient surgical endoscopy through advanced techniques like flexible endoscopic suturing and tissue apposition. Additionally, the company has developed the ENDOMINA platform, which provides gastroenterologists with an open system for performing therapeutic procedures.

Ncardia is a biotechnology company focused on expediting the drug discovery and development process. The company leverages human induced pluripotent stem cell (hiPSC) technology to create predictive human cellular assay systems, which are used for safety and efficacy testing of drug candidates. Additionally, Ncardia enhances cardiovascular and neural drug screening, providing researchers and drug discovery companies with tools to better understand human disease biology. This approach aims to accelerate the overall drug discovery process, facilitating the development of safer and more effective therapeutic options.

Diagenode is an international life sciences company established in 2003 in Liège, Belgium, with a presence in Sparta, New Jersey, and a sales office in the United Kingdom. The company specializes in developing and commercializing advanced instruments and reagent systems for life science research and molecular diagnostics. Diagenode offers a technology platform that includes Bioruptor shearing and IP-Star automation instruments, along with reagent kits and quality antibodies. These products are designed to enhance workflows in epigenetics research, biological sample preparation, and diagnostic assays, serving a diverse clientele that includes prominent epigenetics researchers, academic institutions, genome centers, core laboratories, and pharmaceutical and biotechnology companies.