Canaan Partners

Founded in 2014, Vivace Therapeutics is a biotechnology company based in the San Francisco Bay Area. It focuses on discovering and developing cancer therapeutics by targeting novel pathways, with a particular emphasis on the Hippo pathway which controls tissue regeneration and organ size.

Autobahn Therapeutics develops brain-targeting, small molecule therapies for central nervous system disorders. Its lead program ABX-002 is a thyroid hormone receptor beta agonist being developed as an adjunctive treatment for mood disorders, including major depressive disorder and bipolar depression. The company emphasizes precision tuning of CNS exposure, validated clinical and biologic targets, and biomarker-guided development across neuropsychiatry, neurodegeneration, and neuroinflammation to address high unmet medical needs and improve patient outcomes.

Binarly is a global firmware and software supply chain security company founded in 2021 and based in Los Angeles. Its flagship Binarly Transparency Platform is an enterprise-class, AI-powered solution used by device manufacturers, original equipment manufacturers and product security teams to identify known and unknown vulnerabilities, misconfigurations and signs of malicious code implantation. The platform performs in-depth firmware introspection using proprietary machine learning and code analysis techniques to detect threats that originate below the operating system. Validated remediation playbooks help reduce the cost and time to respond to security exposures, supporting protection for businesses, critical infrastructure and consumers worldwide.

Lily AI is an innovative e-commerce product discovery platform based in Mountain View, California, that focuses on enhancing the sales performance of brands and retailers. The company specializes in integrating customer-centric product attributes into various facets of the e-commerce ecosystem, including site search engines and recommendation systems. By aligning brand messaging with customer intent, Lily AI improves on-site search, personalized product discovery, and demand prediction. This approach enables retailers, particularly in the fashion, home, and beauty sectors, to achieve significant increases in traffic, conversion rates, revenue, and brand loyalty.

JOOR operates a digital wholesale platform that connects fashion brands and retailers worldwide. The system replaces manual ordering with automated B2B order management, payment processing, and virtual showrooms, enabling faster transactions and reduced errors. It supplies data analytics to help users track performance, cut costs, and enhance customer experience. Through a curated network of global partners, the platform supports brands and buyers in building strategic relationships and scaling operations across markets.

Founded in 2021, Atmosfy is a San Francisco-based platform that helps users discover dining and nightlife options through video reviews. It covers restaurants, bars, cafes, and clubs nearby or afar, assisting users in making informed decisions based on their preferences.

Antiva Biosciences, Inc. is a biopharmaceutical company based in South San Francisco, California, focused on developing antiviral therapies for human papillomavirus (HPV) infections. Established in 2012, the company aims to prevent cancer by treating precancerous lesions associated with HPV. Antiva's innovative approach includes localized therapeutics and small molecule antivirals that target HPV and other viral infections. The company is currently conducting clinical trials for high-grade anal intraepithelial neoplasias and high-grade cervical intraepithelial neoplasias. Through its medicinal chemistry platform, Antiva strives to enhance health outcomes for patients affected by HPV-related diseases and other viral infections.

Relievant Medsystems, Inc. is a medical device company focused on developing innovative solutions for chronic axial low back pain. Founded in 2004 and headquartered in Minneapolis, Minnesota, with a development office in Sunnyvale, California, the company has created the Intracept System. This minimally invasive procedure specifically targets the basivertebral nerve, providing relief by blocking pain signal transmission. The Intracept System offers patients a low-risk therapy option aimed at alleviating chronic vertebrogenic low back pain.

Komprise is a multi-cloud data management platform that enables organizations to analyze, move, and access file and object data across on-premises and cloud storage. It uses data growth analytics to identify hot and cold data and manages the data lifecycle across multiple storage vendors, including replication, archiving, and migration. The platform can relocate unstructured data to secondary storage based on criteria such as age, usage, or security to ensure data resides in the appropriate location at the right time. Founded in 2014 and headquartered in Campbell, California, Komprise focuses on intelligent data management to improve data accessibility and storage efficiency.

Lily AI is an innovative e-commerce product discovery platform based in Mountain View, California, that focuses on enhancing the sales performance of brands and retailers. The company specializes in integrating customer-centric product attributes into various facets of the e-commerce ecosystem, including site search engines and recommendation systems. By aligning brand messaging with customer intent, Lily AI improves on-site search, personalized product discovery, and demand prediction. This approach enables retailers, particularly in the fashion, home, and beauty sectors, to achieve significant increases in traffic, conversion rates, revenue, and brand loyalty.

Dusty Robotics, Inc. is a technology company that specializes in automated layout services for the construction industry. Founded in 2018 and headquartered in Mountain View, California, the company has developed the FieldPrinter, a robotic tool that translates digital building information modeling (BIM) designs into accurate, on-site layouts. By integrating BIM information directly onto construction-site floors, Dusty Robotics eliminates manual processes, thereby enhancing efficiency in the construction workflow. The company's innovative solutions serve a diverse clientele, including owners, general contractors, subcontractors, and builders, helping them to reduce labor and material waste and improve the overall design-build-operate lifecycle.

BoostUp.ai offers a sales intelligence platform that transforms unstructured data into actionable insights. Its solution analyzes risks at macro and micro levels, enhancing forecasting accuracy, efficiency, and predictability across the entire sales process. The company serves prominent clients such as Teradata, Degreed, and Iterable.

Rondo Therapeutics is a biopharmaceutical company based in Hayward, California, specializing in the discovery and development of innovative bispecific antibodies aimed at activating the immune system to combat cancer. Founded in 2021, the company focuses on creating cancer immunotherapies specifically for solid tumor types that do not respond to existing immune checkpoint inhibitors. By addressing areas of unmet medical need, Rondo Therapeutics aims to advance novel therapeutic options for patients facing challenging cancer diagnoses.

Gemist is a Los Angeles-based jewelry company established in 2018. It specializes in designing and manufacturing customizable rings and other accessories, with a focus on millennial consumers. Gemist's unique business model allows customers to design their pieces online, receive free replicas for trial at home before purchasing.

Apex.AI develops software for autonomous mobility, offering a framework and tools that simplify the development of safe and secure autonomous driving applications. Its platform includes Apex.OS, which abstracts hardware, middleware, kernels, interfaces, and drivers into usable APIs, and Apex.Autonomy for safety-critical applications. It also offers MARV.Automotive, a data management platform that transfers vehicle data to the cloud, enables dynamic search-based analytics, analyzes partial logs, runs algorithms on real data, and provides graphical data introspection and team collaboration. Founded in 2017 and based in Palo Alto, California, Apex.AI builds on open-source software such as ROS and Eclipse iceoryx to provide building blocks for developers creating AI and safety-critical software for autonomous vehicles.

Founded in 2016, Sounding Board Labs develops a platform that provides personalized coaching for leaders and new managers. Its platform offers executive coaching, connects through phone, video, and chat, creates development plans, and provides surveys and reporting to track progress.

Antiva Biosciences, Inc. is a biopharmaceutical company based in South San Francisco, California, focused on developing antiviral therapies for human papillomavirus (HPV) infections. Established in 2012, the company aims to prevent cancer by treating precancerous lesions associated with HPV. Antiva's innovative approach includes localized therapeutics and small molecule antivirals that target HPV and other viral infections. The company is currently conducting clinical trials for high-grade anal intraepithelial neoplasias and high-grade cervical intraepithelial neoplasias. Through its medicinal chemistry platform, Antiva strives to enhance health outcomes for patients affected by HPV-related diseases and other viral infections.

Bzaar is an online B2B cross-border marketplace founded in 2020 and headquartered in San Francisco, California. The company specializes in connecting small businesses with a diverse range of products, including home improvements, fashion, cookware, and bakeware, primarily sourced from South and South-East Asia. Bzaar provides retailers access to niche and artisanal products from value-based brands that are often unavailable at traditional big-box retail chains. By facilitating cross-border wholesale transactions, Bzaar enhances buying transparency and predictability for small and medium enterprises, allowing them to effectively meet their inventory needs.

MindTickle offers a sales readiness platform that enables companies to train, coach, and align their customer-facing teams. Its data-driven approach combines on-demand training, mobile updates, gamification, coaching, role-play, and assessment tools to enhance sales performance. Headquartered in San Francisco and Pune, MindTickle is privately held.

JOOR operates a digital wholesale platform that connects fashion brands and retailers worldwide. The system replaces manual ordering with automated B2B order management, payment processing, and virtual showrooms, enabling faster transactions and reduced errors. It supplies data analytics to help users track performance, cut costs, and enhance customer experience. Through a curated network of global partners, the platform supports brands and buyers in building strategic relationships and scaling operations across markets.

Dusty Robotics, Inc. is a technology company that specializes in automated layout services for the construction industry. Founded in 2018 and headquartered in Mountain View, California, the company has developed the FieldPrinter, a robotic tool that translates digital building information modeling (BIM) designs into accurate, on-site layouts. By integrating BIM information directly onto construction-site floors, Dusty Robotics eliminates manual processes, thereby enhancing efficiency in the construction workflow. The company's innovative solutions serve a diverse clientele, including owners, general contractors, subcontractors, and builders, helping them to reduce labor and material waste and improve the overall design-build-operate lifecycle.

Embroker, Inc. is a digital insurance brokerage that specializes in providing insurance services to small and mid-sized businesses. Founded in 2015 and headquartered in San Francisco, with additional offices in Chicago, Boston, Denver, and New York, Embroker utilizes an online platform to streamline the process of purchasing, managing, and analyzing commercial insurance policies. The platform allows clients to automate the sharing, requesting, and tracking of proof of coverage, as well as monitor claims in real-time. Embroker offers a wide range of insurance products, including Commercial General Liability, property insurance, professional liability, and employee benefits, among others. The company also provides tools for peer comparison, enabling clients to benchmark their policies against industry standards. By combining technology with broker expertise, Embroker aims to enhance the efficiency and effectiveness of the $800 billion property and casualty insurance market, helping businesses save time and secure optimal coverage.

BoostUp.ai offers a sales intelligence platform that transforms unstructured data into actionable insights. Its solution analyzes risks at macro and micro levels, enhancing forecasting accuracy, efficiency, and predictability across the entire sales process. The company serves prominent clients such as Teradata, Degreed, and Iterable.

Tyra Biosciences is a biotechnology company focused on developing precision therapies for cancer. It uses its proprietary SNAP platform to create next-generation drug candidates that target acquired drug resistance, with an initial focus on the Fibroblast Growth Factor Receptor (FGFR) family.

Axis Security Inc. is a cybersecurity company founded in 2018 and based in Palo Alto, California. It specializes in Zero Trust Network Access solutions, providing a cloud security platform that ensures secure remote access to applications. The company's technology focuses on application isolation and employs a context-aware approach to security, evaluating multiple factors to ensure that only authorized users can access specific resources within a network. This business-centric strategy allows organizations to maintain control over sensitive information and manage access for employees, partners, and other stakeholders effectively.

PerimeterX, Inc. is a cybersecurity company that specializes in developing solutions to prevent automated attacks and malicious web behavior. Founded in 2014 and headquartered in San Mateo, California, with additional locations in London, Miami, and a subsidiary in Tel Aviv, the company offers a suite of products aimed at protecting web infrastructure. Its flagship solutions, known as PerimeterX Bot Defender, provide real-time defenses against various types of bot attacks, including those targeting websites, mobile applications, and APIs. By leveraging behavioral analytics and advanced threat detection techniques, PerimeterX helps organizations in sectors such as e-commerce, travel, and media safeguard their digital assets from account abuse, web scraping, and marketing fraud. The company's innovative approach has garnered recognition, including being listed among the top cybersecurity startups and promising artificial intelligence firms.

Founded in 2016, Sounding Board Labs develops a platform that provides personalized coaching for leaders and new managers. Its platform offers executive coaching, connects through phone, video, and chat, creates development plans, and provides surveys and reporting to track progress.

Apartment List is an online rental marketplace in the United States that connects renters with landlords. The platform offers a search experience with details on prices, locations, and amenities through web and mobile interfaces. The company emphasizes a fair, transparent, and simple renting process and provides a personalized search that learns user preferences to streamline finding suitable apartments. Based in San Francisco, it serves tenants and property owners by helping users discover listings and make informed decisions, reducing time and hassle in the search. Established in the late 2000s, Apartment List aims to make the home-finding process more personal, flexible, and efficient.

Founded in 2014, Vivace Therapeutics is a biotechnology company based in the San Francisco Bay Area. It focuses on discovering and developing cancer therapeutics by targeting novel pathways, with a particular emphasis on the Hippo pathway which controls tissue regeneration and organ size.

Mate Fertility is a technology-driven fertility clinic founded in 2020 and based in Los Angeles, California. The company aims to make parenthood more accessible by providing comprehensive fertility services at affordable prices. It operates a platform that connects patients to fertility clinics and offers telemedicine options for various treatments and therapies. By delivering end-to-end fertility services, Mate Fertility ensures that patients receive expert guidance and care throughout their fertility journey, making the process more comfortable and manageable.

MindTickle offers a sales readiness platform that enables companies to train, coach, and align their customer-facing teams. Its data-driven approach combines on-demand training, mobile updates, gamification, coaching, role-play, and assessment tools to enhance sales performance. Headquartered in San Francisco and Pune, MindTickle is privately held.

Relievant Medsystems, Inc. is a medical device company focused on developing innovative solutions for chronic axial low back pain. Founded in 2004 and headquartered in Minneapolis, Minnesota, with a development office in Sunnyvale, California, the company has created the Intracept System. This minimally invasive procedure specifically targets the basivertebral nerve, providing relief by blocking pain signal transmission. The Intracept System offers patients a low-risk therapy option aimed at alleviating chronic vertebrogenic low back pain.

Vineti, Inc. is a technology company focused on advancing the development and delivery of personalized therapies, particularly in the realm of cell and gene treatments for serious conditions like cancer. Founded in 2016 and headquartered in San Francisco, California, Vineti offers a cloud-based platform known as the Personalized Therapy Management (PTM) platform. This platform integrates various aspects of the therapeutic supply chain, including operations, manufacturing, quality assurance, and regulatory compliance, to streamline and automate processes. It addresses critical challenges faced by patients, healthcare providers, pharmaceutical companies, and regulatory bodies in the commercialization of personalized medicine. By enhancing supply chain orchestration and ensuring compliance with regulatory standards, Vineti aims to expand patient access to innovative therapies. The company also maintains regional offices in Bethesda, Maryland, and Yerevan, Armenia.

Axis Security Inc. is a cybersecurity company founded in 2018 and based in Palo Alto, California. It specializes in Zero Trust Network Access solutions, providing a cloud security platform that ensures secure remote access to applications. The company's technology focuses on application isolation and employs a context-aware approach to security, evaluating multiple factors to ensure that only authorized users can access specific resources within a network. This business-centric strategy allows organizations to maintain control over sensitive information and manage access for employees, partners, and other stakeholders effectively.

Synthekine Inc. is a biotechnology company based in Menlo Park, California, specializing in the development of engineered cytokine therapies and immunotherapies aimed at treating cancer and autoimmune disorders. Founded in 2018, Synthekine utilizes advanced platform technologies, including engineered partial agonists and orthogonal cell therapies, to enhance the efficacy of cytokines while minimizing their toxic side effects. The company's innovative Synthekine Platform employs surrogate agonists instead of traditional mutant cytokines to create selective immunotherapies. Its product pipeline features candidates such as STK-009, an orthogonal ligand paired with SYNCAR-001, an orthogonal receptor-modified CAR-T therapy targeting CD-19. Additionally, Synthekine is developing STK-012, partial agonists of IL-2, and other novel immunotherapies that integrate cytokine receptors to initiate new signaling pathways without relying on wild-type cytokines.

ManiMe, Inc. is a company based in Santa Monica, California, that develops, manufactures, and sells ready-to-wear manicures. Founded in 2017, it specializes in stick-on gels created using advanced 3D printing technology. The company's products are available for purchase online, providing a convenient solution for busy women who wish to maintain their nail care without the need for traditional salon visits. Additionally, ManiMe offers a platform for nail artists, fostering their growth and aligning with their professional aspirations.

BoostUp.ai offers a sales intelligence platform that transforms unstructured data into actionable insights. Its solution analyzes risks at macro and micro levels, enhancing forecasting accuracy, efficiency, and predictability across the entire sales process. The company serves prominent clients such as Teradata, Degreed, and Iterable.

Zibo Inc. is a financial services company that specializes in providing a banking and payments platform tailored for independent landlords. Established in 2018 and based in Redwood City, California, Zibo offers a range of services designed to streamline the management of rental properties. Its platform facilitates rent payments, automates rent collection, and assists with financial management tasks such as tax preparation and accounting. Additionally, Zibo provides tools for tenant screening and rental applications, along with insurance services for residential rental properties. By offering a comprehensive suite of services at no cost, Zibo aims to help landlords enhance cash flow and effectively manage their rental portfolios.

Juno Residential, Inc. is a company focused on the development of residential apartments, incorporating innovative construction methods to provide environmentally friendly housing solutions. Based in San Francisco, California, Juno specializes in prefabricated houses, utilizing techniques that emphasize speed and efficiency. The company is committed to sustainability, employing organic and low-carbon materials, such as mass timber, in its projects. By offering modern and curated living spaces, Juno aims to address the growing demand for sustainable housing alternatives in urban environments. Founded in 2018, Juno Residential, Inc. was previously known as Lighthouse Residential, Inc.

Hallo, Co. is a San Francisco-based company that specializes in creating an online hiring events platform aimed at fostering connections between students, universities, and employers. Founded in 2017, Hallo offers a range of digital services, including career fairs, tech talks, and all-hands meetings, to facilitate effective recruitment and networking opportunities. Additionally, Hallo positions itself as the first AI-driven career platform, providing job seekers with on-demand coaching, interview training, and access to actionable networks. Through its innovative approach, Hallo seeks to enhance the job search experience and improve outcomes for both candidates and companies.

Ladder is a digital life insurance company founded in 2015. It offers flexible term coverage up to $8M across all U.S. states, with an all-digital application process and real-time underwriting, aiming to make life insurance more accessible and affordable.

Leanplum Inc. is a mobile marketing platform that specializes in enhancing engagement for brands through a unified, multichannel approach. Founded in 2012 and headquartered in San Francisco, with additional offices in New York, London, Bulgaria, and Amsterdam, Leanplum enables businesses to optimize their mobile applications and marketing efforts. The platform offers a range of services including messaging, automation, app editing, personalization, A/B testing, and analytics, allowing product teams to conduct real-time optimization tests and analyze results effectively. Renowned global brands such as Tinder, Grab, Tesco, and Zynga utilize Leanplum to orchestrate integrated campaigns that foster customer loyalty and drive growth. By transforming data into actionable insights, Leanplum helps companies understand user needs, delivering relevant experiences that enhance brand engagement and establish long-term customer relationships.

Vineti, Inc. is a technology company focused on advancing the development and delivery of personalized therapies, particularly in the realm of cell and gene treatments for serious conditions like cancer. Founded in 2016 and headquartered in San Francisco, California, Vineti offers a cloud-based platform known as the Personalized Therapy Management (PTM) platform. This platform integrates various aspects of the therapeutic supply chain, including operations, manufacturing, quality assurance, and regulatory compliance, to streamline and automate processes. It addresses critical challenges faced by patients, healthcare providers, pharmaceutical companies, and regulatory bodies in the commercialization of personalized medicine. By enhancing supply chain orchestration and ensuring compliance with regulatory standards, Vineti aims to expand patient access to innovative therapies. The company also maintains regional offices in Bethesda, Maryland, and Yerevan, Armenia.

Tyra Biosciences is a biotechnology company focused on developing precision therapies for cancer. It uses its proprietary SNAP platform to create next-generation drug candidates that target acquired drug resistance, with an initial focus on the Fibroblast Growth Factor Receptor (FGFR) family.

Lily AI is an innovative e-commerce product discovery platform based in Mountain View, California, that focuses on enhancing the sales performance of brands and retailers. The company specializes in integrating customer-centric product attributes into various facets of the e-commerce ecosystem, including site search engines and recommendation systems. By aligning brand messaging with customer intent, Lily AI improves on-site search, personalized product discovery, and demand prediction. This approach enables retailers, particularly in the fashion, home, and beauty sectors, to achieve significant increases in traffic, conversion rates, revenue, and brand loyalty.

Capella Space is an information services company based in San Francisco that operates a constellation of small satellites equipped with synthetic aperture radar, delivering on-demand, high-resolution radar imagery of the Earth's surface. The SAR imagery can be acquired through clouds, smoke, fog, and darkness, enabling continuous global monitoring and rapid insight across industries. Capella's services support infrastructure monitoring, agriculture, disaster response, maritime domain awareness, city planning and mapping, and business intelligence, helping customers detect sub-meter surface changes, track economic activity, and monitor environmental and security-related conditions. Founded in 2016, Capella Space provides timely earth observation for commerce, conservation, and safety.

Apex.AI develops software for autonomous mobility, offering a framework and tools that simplify the development of safe and secure autonomous driving applications. Its platform includes Apex.OS, which abstracts hardware, middleware, kernels, interfaces, and drivers into usable APIs, and Apex.Autonomy for safety-critical applications. It also offers MARV.Automotive, a data management platform that transfers vehicle data to the cloud, enables dynamic search-based analytics, analyzes partial logs, runs algorithms on real data, and provides graphical data introspection and team collaboration. Founded in 2017 and based in Palo Alto, California, Apex.AI builds on open-source software such as ROS and Eclipse iceoryx to provide building blocks for developers creating AI and safety-critical software for autonomous vehicles.

Intrepida Bio, Inc. is a biotechnology company focused on developing innovative cancer therapies that enhance the body’s innate immune response. Founded in 2016 and headquartered in San Diego, California, the company specializes in creating medicines that modulate the innate immune system to combat cancer and other diseases. Intrepida Bio is particularly engaged in the development of monoclonal antibodies aimed at novel targets such as BAG3 and its receptor IFITM-2, which are involved in establishing a tumor-friendly environment. Through its research efforts, Intrepida Bio aims to provide patients with effective treatment options to fight cancer.

Astra Space, Inc. is a technology company based in Alameda, California, that specializes in designing and building rockets for satellite delivery and launch services. Founded in 2004 and originally known as Ventions LLC, the company rebranded in 2016 and aims to provide accessible and affordable access to space. Astra offers online reservations for payload deliveries to both sun-synchronous and low inclination orbits, with a focus on dedicated launch services for payloads ranging from 50 kg to 150 kg. The business is divided into two segments: Launch Services, which provides rapid global launch capabilities, and Space Products, which includes the development of space products tailored to customer needs for successful satellite launches. Astra operates test facilities to support its operations and is committed to facilitating frequent access to space for satellite operators and governments.

PerimeterX, Inc. is a cybersecurity company that specializes in developing solutions to prevent automated attacks and malicious web behavior. Founded in 2014 and headquartered in San Mateo, California, with additional locations in London, Miami, and a subsidiary in Tel Aviv, the company offers a suite of products aimed at protecting web infrastructure. Its flagship solutions, known as PerimeterX Bot Defender, provide real-time defenses against various types of bot attacks, including those targeting websites, mobile applications, and APIs. By leveraging behavioral analytics and advanced threat detection techniques, PerimeterX helps organizations in sectors such as e-commerce, travel, and media safeguard their digital assets from account abuse, web scraping, and marketing fraud. The company's innovative approach has garnered recognition, including being listed among the top cybersecurity startups and promising artificial intelligence firms.

MindTickle offers a sales readiness platform that enables companies to train, coach, and align their customer-facing teams. Its data-driven approach combines on-demand training, mobile updates, gamification, coaching, role-play, and assessment tools to enhance sales performance. Headquartered in San Francisco and Pune, MindTickle is privately held.

Founded in 1985, Commonwealth Labs operates a specialized diagnostic laboratory based in San Francisco. It offers advanced tests for functional gastrointestinal disorders, serving healthcare providers.

Tia, Inc. is a health advisory platform focused on providing personalized and data-driven healthcare solutions for women. Founded in 2015 and headquartered in New York, with an additional location in San Francisco, Tia offers a mobile application that features a range of services including birth control recommendations, sexual health advice, symptom tracking, and doctor locators. The platform empowers women to make informed decisions about their health by facilitating access to both in-office appointments and virtual care. Recognizing that traditional healthcare systems often overlook women's needs, Tia aims to create a distinctly female-centered model of care that addresses the unique healthcare challenges women face.

JOOR operates a digital wholesale platform that connects fashion brands and retailers worldwide. The system replaces manual ordering with automated B2B order management, payment processing, and virtual showrooms, enabling faster transactions and reduced errors. It supplies data analytics to help users track performance, cut costs, and enhance customer experience. Through a curated network of global partners, the platform supports brands and buyers in building strategic relationships and scaling operations across markets.

PerimeterX, Inc. is a cybersecurity company that specializes in developing solutions to prevent automated attacks and malicious web behavior. Founded in 2014 and headquartered in San Mateo, California, with additional locations in London, Miami, and a subsidiary in Tel Aviv, the company offers a suite of products aimed at protecting web infrastructure. Its flagship solutions, known as PerimeterX Bot Defender, provide real-time defenses against various types of bot attacks, including those targeting websites, mobile applications, and APIs. By leveraging behavioral analytics and advanced threat detection techniques, PerimeterX helps organizations in sectors such as e-commerce, travel, and media safeguard their digital assets from account abuse, web scraping, and marketing fraud. The company's innovative approach has garnered recognition, including being listed among the top cybersecurity startups and promising artificial intelligence firms.

Agile Stacks, Inc. is a technology company based in San Mateo, California, founded in 2016. It specializes in providing a DevOps automation platform designed to optimize cloud infrastructure and enhance machine learning processes. By offering composable, automated stacks, Agile Stacks enables enterprises to accelerate software delivery and streamline data science initiatives. The company's cloud-based services facilitate the implementation of multi-cloud infrastructure-as-code, allowing organizations to deploy comprehensive software infrastructure in a matter of minutes. Agile Stacks aims to simplify and improve the efficiency of managing cloud resources for its clients.

Komprise is a multi-cloud data management platform that enables organizations to analyze, move, and access file and object data across on-premises and cloud storage. It uses data growth analytics to identify hot and cold data and manages the data lifecycle across multiple storage vendors, including replication, archiving, and migration. The platform can relocate unstructured data to secondary storage based on criteria such as age, usage, or security to ensure data resides in the appropriate location at the right time. Founded in 2014 and headquartered in Campbell, California, Komprise focuses on intelligent data management to improve data accessibility and storage efficiency.

Embroker, Inc. is a digital insurance brokerage that specializes in providing insurance services to small and mid-sized businesses. Founded in 2015 and headquartered in San Francisco, with additional offices in Chicago, Boston, Denver, and New York, Embroker utilizes an online platform to streamline the process of purchasing, managing, and analyzing commercial insurance policies. The platform allows clients to automate the sharing, requesting, and tracking of proof of coverage, as well as monitor claims in real-time. Embroker offers a wide range of insurance products, including Commercial General Liability, property insurance, professional liability, and employee benefits, among others. The company also provides tools for peer comparison, enabling clients to benchmark their policies against industry standards. By combining technology with broker expertise, Embroker aims to enhance the efficiency and effectiveness of the $800 billion property and casualty insurance market, helping businesses save time and secure optimal coverage.

Apex.AI develops software for autonomous mobility, offering a framework and tools that simplify the development of safe and secure autonomous driving applications. Its platform includes Apex.OS, which abstracts hardware, middleware, kernels, interfaces, and drivers into usable APIs, and Apex.Autonomy for safety-critical applications. It also offers MARV.Automotive, a data management platform that transfers vehicle data to the cloud, enables dynamic search-based analytics, analyzes partial logs, runs algorithms on real data, and provides graphical data introspection and team collaboration. Founded in 2017 and based in Palo Alto, California, Apex.AI builds on open-source software such as ROS and Eclipse iceoryx to provide building blocks for developers creating AI and safety-critical software for autonomous vehicles.

Founded in 2015, SKALE Labs develops a scalable blockchain platform that enables high-speed consensus for decentralized applications (dApps). It empowers dApps to run smart contracts at millions of transactions per second on platforms like Ethereum and EOS. The SKALE Network is a fully decentralized, open-source P2P network supported by the SKALE utility token.

MachEye Inc. is a technology company based in San Jose, California, founded in 2018. It specializes in developing an integrated cloud-native platform that enables businesses to harness their data through innovative analytics automation. The platform provides search and click-less intelligence, delivering insights in the form of interactive audio-visuals. MachEye's solutions facilitate digital behavioral analysis, customer behavior assessment, and billing analysis, allowing organizations to uncover actionable insights and improve decision-making speed. By leveraging artificial intelligence, MachEye aims to empower users across various business functions to access personalized business intelligence seamlessly, thereby enhancing user engagement and identifying new opportunities.

Aeva Technologies develops sensing and perception technologies for autonomous systems by integrating vision, depth, and motion sensing into a single platform. Its core Frequency Modulated Continuous Wave (FMCW) LiDAR on chip enables 4D LiDAR with longer range, higher resolution, and the ability to measure velocity for every pixel, delivering robust performance in varying weather conditions. The company targets automated driving and applications across consumer electronics, health, industrial automation, and security. Founded in 2016 and based in California, Aeva operates globally.

Highrise is a creative mobile community where people create avatars, express themselves, and make friends. Its platform includes built-in user-generated avatars that let its users engage in real-time virtual chats, read reviews, surf across the latest news feed and keep in touch with their friends to customize and self-designed games, enabling users to make new friends, host real-time games and create fun contents for publicizing. It was founded in 2018 and is headquartered in San Francisco, California.

Bumblebee Spaces is a San Francisco-based company founded in 2017 that specializes in creating innovative home furnishings through robotics and artificial intelligence. The company's primary product is a modular ceiling system designed to address storage needs by utilizing smart robots and AI technology. This system allows users to store, manage, and retrieve objects on-demand within the ceiling space, effectively increasing usable living area. Bumblebee Spaces also offers a mobile application that enables users to move and preview stored items. The company's approach focuses on maximizing space efficiency by thinking in cubic feet rather than square feet, providing a novel solution for modern living spaces.

Cargomatic, Inc. is a technology-driven transportation platform that connects shippers with pre-screened carriers in real-time, primarily serving the short-haul and drayage trucking markets. Founded in 2013 and headquartered in Venice, California, Cargomatic facilitates an on-demand network for local truck availability, allowing shippers to submit loads and quickly find nearby trucks to meet their logistics needs. Since its launch in early 2014, the company has successfully supported tens of thousands of deliveries across California, Chicago, and metropolitan New York. By streamlining communication and reducing the reliance on traditional booking methods, Cargomatic enhances service levels, improves pick-up times and delivery rates, and enables customers to manage their outsourced transportation vendors more effectively through a single platform.

The RealReal operates an online marketplace for authenticated luxury resale, offering fashion for women, men and kids, as well as jewelry, watches, art and home items. Founded in 2011 and headquartered in San Francisco, it functions as a full-service consignment platform that authenticates every item through in-house experts and uses technology to determine pricing, while managing photography, listings, payments and shipping. It is the largest pure-play luxury resale platform in the United States and supports a sustainable circular economy by facilitating resale across multiple categories. The company generates revenue primarily from consignments and first-party sales on its marketplace, with additional direct sales, and provides services such as virtual appointments, in-home pickup and direct shipping to buyers.

Antiva Biosciences, Inc. is a biopharmaceutical company based in South San Francisco, California, focused on developing antiviral therapies for human papillomavirus (HPV) infections. Established in 2012, the company aims to prevent cancer by treating precancerous lesions associated with HPV. Antiva's innovative approach includes localized therapeutics and small molecule antivirals that target HPV and other viral infections. The company is currently conducting clinical trials for high-grade anal intraepithelial neoplasias and high-grade cervical intraepithelial neoplasias. Through its medicinal chemistry platform, Antiva strives to enhance health outcomes for patients affected by HPV-related diseases and other viral infections.

Relievant Medsystems, Inc. is a medical device company focused on developing innovative solutions for chronic axial low back pain. Founded in 2004 and headquartered in Minneapolis, Minnesota, with a development office in Sunnyvale, California, the company has created the Intracept System. This minimally invasive procedure specifically targets the basivertebral nerve, providing relief by blocking pain signal transmission. The Intracept System offers patients a low-risk therapy option aimed at alleviating chronic vertebrogenic low back pain.

EndoGastric Solutions, Inc. is a medical device company focused on developing and commercializing innovative surgical technologies for the treatment of gastrointestinal diseases, particularly gastroesophageal reflux disease (GERD). The company offers products such as EsophyX, which enables transoral reconstructive surgery, and the EsophyX Z device used in the transoral incisionless fundoplication procedure. Additionally, EndoGastric Solutions provides SerosaFuse Fasteners, a non-resorbable polypropylene material with strength comparable to traditional sutures. Beyond its product offerings, the company supports healthcare professionals through trainer-led courses and various consultative services, including pre-authorization and medical review. Founded in 2002 and headquartered in Redmond, Washington, with an additional office in San Mateo, California, EndoGastric Solutions was previously known as EsophyX, Inc. before its rebranding in January 2005.

Highrise is a creative mobile community where people create avatars, express themselves, and make friends. Its platform includes built-in user-generated avatars that let its users engage in real-time virtual chats, read reviews, surf across the latest news feed and keep in touch with their friends to customize and self-designed games, enabling users to make new friends, host real-time games and create fun contents for publicizing. It was founded in 2018 and is headquartered in San Francisco, California.

PACT Pharma, Inc. is a biotechnology company focused on developing personalized cell-based therapies for cancer treatment. The company specializes in neoantigen-specific adoptive T-cell therapies aimed at solid tumors. Its innovative platform utilizes bioinformatics to analyze patients' tumor and normal DNA and RNA, identifying candidate neoantigen peptides that stimulate robust antitumor T-cell responses. By pinpointing neo-epitopes unique to each patient's cancer, PACT Pharma enables the engineering of autologous T cells that specifically target and eradicate tumors expressing these neo-antigens. Founded in 2016 and headquartered in South San Francisco, California, PACT Pharma is dedicated to advancing personalized medicine in oncology.

Vineti, Inc. is a technology company focused on advancing the development and delivery of personalized therapies, particularly in the realm of cell and gene treatments for serious conditions like cancer. Founded in 2016 and headquartered in San Francisco, California, Vineti offers a cloud-based platform known as the Personalized Therapy Management (PTM) platform. This platform integrates various aspects of the therapeutic supply chain, including operations, manufacturing, quality assurance, and regulatory compliance, to streamline and automate processes. It addresses critical challenges faced by patients, healthcare providers, pharmaceutical companies, and regulatory bodies in the commercialization of personalized medicine. By enhancing supply chain orchestration and ensuring compliance with regulatory standards, Vineti aims to expand patient access to innovative therapies. The company also maintains regional offices in Bethesda, Maryland, and Yerevan, Armenia.

Unchained Labs is a life sciences tools company based in Pleasanton, California, specializing in solutions for biologics and gene therapy researchers. Established in 2014, it develops a range of products designed to enhance the efficiency and effectiveness of research in protein stability and formulation. Key offerings include the Optim platform, which allows researchers to measure multiple protein stability parameters simultaneously, and GRUNT, an automated system for biologic formulation preparation. In addition to these, the company provides various tools such as protein sizing systems, stability quantifiers, and automated buffer exchange systems. Unchained Labs serves biopharma and academic customers globally, distributing its products through partnerships in Europe, North and South America, Japan, and other Asian markets.

IDEAYA Biosciences is an oncology-focused biotechnology company dedicated to discovering targeted therapeutics for patient populations selected using molecular diagnostics. Its pipeline includes small molecule inhibitors targeting DNA damage and repair pathways, such as MAT2A, PARG, and Pol-theta, as well as immuno-oncology therapies targeting the tumor microenvironment.

Imanis Data is a San Jose-based company that specializes in subscription-based data availability management solutions for enterprise-scale environments. Founded in 2012 and formerly known as Talena, the company offers two primary products: FastFind, a metadata catalog that simplifies Big Data application management across various platforms, and Imanis Data 3.0, a backup and recovery platform designed to detect ransomware attacks early and prevent accidental data loss. These solutions are architected for petabyte-scale datasets and leverage machine learning to minimize risk and reduce costs. As of May 2019, Imanis Data operates as a subsidiary of Cohesity, Inc.

Apartment List is an online rental marketplace in the United States that connects renters with landlords. The platform offers a search experience with details on prices, locations, and amenities through web and mobile interfaces. The company emphasizes a fair, transparent, and simple renting process and provides a personalized search that learns user preferences to streamline finding suitable apartments. Based in San Francisco, it serves tenants and property owners by helping users discover listings and make informed decisions, reducing time and hassle in the search. Established in the late 2000s, Apartment List aims to make the home-finding process more personal, flexible, and efficient.

Ladder is a digital life insurance company founded in 2015. It offers flexible term coverage up to $8M across all U.S. states, with an all-digital application process and real-time underwriting, aiming to make life insurance more accessible and affordable.

Genome Medical operates a platform that connects individuals and healthcare providers with genetic specialists. It offers virtual genetic care services, including clinical consultations for various health areas like cancer, cardiology, and reproductive health. The company uses its Genome Care Delivery technology to facilitate efficient genetic assessments and personalized treatment plans.

MindTickle offers a sales readiness platform that enables companies to train, coach, and align their customer-facing teams. Its data-driven approach combines on-demand training, mobile updates, gamification, coaching, role-play, and assessment tools to enhance sales performance. Headquartered in San Francisco and Pune, MindTickle is privately held.

Leanplum Inc. is a mobile marketing platform that specializes in enhancing engagement for brands through a unified, multichannel approach. Founded in 2012 and headquartered in San Francisco, with additional offices in New York, London, Bulgaria, and Amsterdam, Leanplum enables businesses to optimize their mobile applications and marketing efforts. The platform offers a range of services including messaging, automation, app editing, personalization, A/B testing, and analytics, allowing product teams to conduct real-time optimization tests and analyze results effectively. Renowned global brands such as Tinder, Grab, Tesco, and Zynga utilize Leanplum to orchestrate integrated campaigns that foster customer loyalty and drive growth. By transforming data into actionable insights, Leanplum helps companies understand user needs, delivering relevant experiences that enhance brand engagement and establish long-term customer relationships.

Ascendify Corporation specializes in developing innovative talent management solutions that transform how companies attract, develop, and retain employees. The company's flagship product, the Intelligent People Management platform, utilizes machine learning and predictive analytics to streamline recruiting and talent development processes. This cloud-based platform enables organizations to effectively identify and connect with potential candidates while also assessing their skills and training needs. Headquartered in San Francisco, Ascendify serves a diverse clientele, including prominent corporations such as GE, Cisco, Panasonic, Disney, Deloitte, and Marriott, reinforcing its position as a key player in the talent acquisition software industry.

Founded in 2010, UrbanSitter operates a childcare marketplace that connects parents with trusted babysitters and nannies recommended by people within their network. The platform also offers services for pet sitting, housekeeping, tutoring, and senior care. With a focus on convenience and reliability, UrbanSitter enables users to book caregivers at short notice.

PerimeterX, Inc. is a cybersecurity company that specializes in developing solutions to prevent automated attacks and malicious web behavior. Founded in 2014 and headquartered in San Mateo, California, with additional locations in London, Miami, and a subsidiary in Tel Aviv, the company offers a suite of products aimed at protecting web infrastructure. Its flagship solutions, known as PerimeterX Bot Defender, provide real-time defenses against various types of bot attacks, including those targeting websites, mobile applications, and APIs. By leveraging behavioral analytics and advanced threat detection techniques, PerimeterX helps organizations in sectors such as e-commerce, travel, and media safeguard their digital assets from account abuse, web scraping, and marketing fraud. The company's innovative approach has garnered recognition, including being listed among the top cybersecurity startups and promising artificial intelligence firms.

Unchained Labs is a life sciences tools company based in Pleasanton, California, specializing in solutions for biologics and gene therapy researchers. Established in 2014, it develops a range of products designed to enhance the efficiency and effectiveness of research in protein stability and formulation. Key offerings include the Optim platform, which allows researchers to measure multiple protein stability parameters simultaneously, and GRUNT, an automated system for biologic formulation preparation. In addition to these, the company provides various tools such as protein sizing systems, stability quantifiers, and automated buffer exchange systems. Unchained Labs serves biopharma and academic customers globally, distributing its products through partnerships in Europe, North and South America, Japan, and other Asian markets.

Founded in 2014, Vivace Therapeutics is a biotechnology company based in the San Francisco Bay Area. It focuses on discovering and developing cancer therapeutics by targeting novel pathways, with a particular emphasis on the Hippo pathway which controls tissue regeneration and organ size.

Beam Solutions is a venture-backed regulatory technology (regtech) software company based in the San Francisco Bay Area. It specializes in developing an anti-money laundering platform that addresses compliance challenges faced by financial institutions. Beam's proprietary transaction monitoring technologies utilize advanced machine learning and innovative data sources to significantly reduce false positives and enhance the detection of suspicious activities. This end-to-end compliance solution not only improves efficiency but also helps banks, credit unions, and fintech companies navigate the complexities of regulatory requirements. By employing a transparent-box approach, Beam elucidates its machine learning processes, ensuring clarity for regulators and bolstering their understanding and approval. The company is supported by a knowledgeable team of officers, directors, advisors, and investors.

Genome Medical operates a platform that connects individuals and healthcare providers with genetic specialists. It offers virtual genetic care services, including clinical consultations for various health areas like cancer, cardiology, and reproductive health. The company uses its Genome Care Delivery technology to facilitate efficient genetic assessments and personalized treatment plans.

Cardlytics operates an advertising platform within financial institutions' digital channels, enabling marketers to reach consumers through trusted online and mobile banking channels. It uses purchase-based intelligence to make marketing more relevant and measurable, partnering with over 1,500 financial institutions worldwide.

Antiva Biosciences, Inc. is a biopharmaceutical company based in South San Francisco, California, focused on developing antiviral therapies for human papillomavirus (HPV) infections. Established in 2012, the company aims to prevent cancer by treating precancerous lesions associated with HPV. Antiva's innovative approach includes localized therapeutics and small molecule antivirals that target HPV and other viral infections. The company is currently conducting clinical trials for high-grade anal intraepithelial neoplasias and high-grade cervical intraepithelial neoplasias. Through its medicinal chemistry platform, Antiva strives to enhance health outcomes for patients affected by HPV-related diseases and other viral infections.

Unifi Software, Inc. develops a suite of self-service data integration tools designed for both business users and IT professionals. Its flagship products include the Unifi catalog, which utilizes AI technology for data crawling and asset collection, allowing users to identify and process critical data assets. This catalog supports user-friendly search, collaboration, and data governance for enhanced security. Additionally, the Unifi data platform facilitates data acquisition, discovery, enrichment, transformation, normalization, and formatting, while also handling unstructured data. IT professionals benefit from features that enable connection to data sources, user authorization, and resource management. The platform is accessible through the Microsoft Azure Marketplace and offers solutions for various applications, including audience analytics and cloud migration. Founded in 2013 and based in San Mateo, California, Unifi Software operates as a subsidiary of Boomi, Inc.

Dauntless Pharmaceuticals, Inc. is a biopharmaceutical company based in San Diego, California, founded in 2015. It specializes in the development and manufacturing of specialty pharmaceutical drugs, particularly therapeutics for endocrine cancers. The company is known for its lead product, Dauntless 1, which targets endocrine cancers, and is also developing DP1038, another therapeutic agent for the same purpose. Dauntless Pharmaceuticals aims to provide innovative treatment options, including non-injectable alternatives to existing somatostatin analogs, which are commonly administered via injection for conditions such as acromegaly and neuroendocrine tumors. This focus on non-invasive therapies seeks to improve patient access and comfort in managing these conditions.

Agile Stacks, Inc. is a technology company based in San Mateo, California, founded in 2016. It specializes in providing a DevOps automation platform designed to optimize cloud infrastructure and enhance machine learning processes. By offering composable, automated stacks, Agile Stacks enables enterprises to accelerate software delivery and streamline data science initiatives. The company's cloud-based services facilitate the implementation of multi-cloud infrastructure-as-code, allowing organizations to deploy comprehensive software infrastructure in a matter of minutes. Agile Stacks aims to simplify and improve the efficiency of managing cloud resources for its clients.

Zugata is a performance management system focused on enhancing employee and organizational performance through data-driven insights. Founded in 2014 and based in Palo Alto, California, the company offers an AI-based platform that facilitates continuous feedback among employees, helping them to realize their full potential. Zugata's advanced analytics and deep learning algorithms enable managers to aggregate and summarize skill ratings across the organization, teams, or individual employees. This holistic view of workforce strengths and weaknesses allows for informed decision-making regarding future training needs and fosters a corporate culture centered on empowerment and growth.

ReVision Optics, Inc. is a company that specializes in designing, manufacturing, and delivering implantable products aimed at treating presbyopia, a condition associated with the natural aging process that affects near vision. The company's flagship product, the PRESBYLENS Corneal Inlay, offers a patented refractive surgery solution that enhances visual acuity for individuals experiencing age-related vision loss. Founded in 1996 and based in Lake Forest, California, ReVision Optics serves ophthalmology professionals, providing them with advanced technology to improve patient outcomes. Originally established as IntraLens Vision, Inc., the company rebranded to its current name in 2005, reflecting its focus on innovative optical solutions.

Apartment List is an online rental marketplace in the United States that connects renters with landlords. The platform offers a search experience with details on prices, locations, and amenities through web and mobile interfaces. The company emphasizes a fair, transparent, and simple renting process and provides a personalized search that learns user preferences to streamline finding suitable apartments. Based in San Francisco, it serves tenants and property owners by helping users discover listings and make informed decisions, reducing time and hassle in the search. Established in the late 2000s, Apartment List aims to make the home-finding process more personal, flexible, and efficient.

Ladder is a digital life insurance company founded in 2015. It offers flexible term coverage up to $8M across all U.S. states, with an all-digital application process and real-time underwriting, aiming to make life insurance more accessible and affordable.

Leanplum Inc. is a mobile marketing platform that specializes in enhancing engagement for brands through a unified, multichannel approach. Founded in 2012 and headquartered in San Francisco, with additional offices in New York, London, Bulgaria, and Amsterdam, Leanplum enables businesses to optimize their mobile applications and marketing efforts. The platform offers a range of services including messaging, automation, app editing, personalization, A/B testing, and analytics, allowing product teams to conduct real-time optimization tests and analyze results effectively. Renowned global brands such as Tinder, Grab, Tesco, and Zynga utilize Leanplum to orchestrate integrated campaigns that foster customer loyalty and drive growth. By transforming data into actionable insights, Leanplum helps companies understand user needs, delivering relevant experiences that enhance brand engagement and establish long-term customer relationships.

Capella Space is an information services company based in San Francisco that operates a constellation of small satellites equipped with synthetic aperture radar, delivering on-demand, high-resolution radar imagery of the Earth's surface. The SAR imagery can be acquired through clouds, smoke, fog, and darkness, enabling continuous global monitoring and rapid insight across industries. Capella's services support infrastructure monitoring, agriculture, disaster response, maritime domain awareness, city planning and mapping, and business intelligence, helping customers detect sub-meter surface changes, track economic activity, and monitor environmental and security-related conditions. Founded in 2016, Capella Space provides timely earth observation for commerce, conservation, and safety.

Relievant Medsystems, Inc. is a medical device company focused on developing innovative solutions for chronic axial low back pain. Founded in 2004 and headquartered in Minneapolis, Minnesota, with a development office in Sunnyvale, California, the company has created the Intracept System. This minimally invasive procedure specifically targets the basivertebral nerve, providing relief by blocking pain signal transmission. The Intracept System offers patients a low-risk therapy option aimed at alleviating chronic vertebrogenic low back pain.

Beckon, Inc. is a software company specializing in omnichannel analytics for marketers, founded in 2011 and headquartered in San Mateo, California. It offers a software-as-a-service platform that integrates marketing data to provide performance analytics and visualization solutions. Beckon's software delivers real-time marketing intelligence through automated data management, allowing marketers to gain total visibility into cross-channel performance. The platform features pre-built dashboards, scorecards, and key performance indicators, enabling users to make informed decisions swiftly and maximize return on investment. As of November 2018, Beckon operates as a subsidiary of Aclate, Inc. Its goal is to aid marketers in organizing complex data and effectively demonstrating the impact of marketing efforts on business outcomes.