Cintrifuse

Cintrifuse is a Cincinnati-based organization that connects entrepreneurs with strategic partners, mentors, researchers and investors to help launch high-growth startups. It coordinates the region’s innovation ecosystem by linking incubators, accelerators, investment sources, companies and other resources to enhance information sharing and collaboration. Founded in 2012, Cintrifuse operates as an accelerator and ecosystem builder focused on Cincinnati-area ventures, expanding access to mentorship, partnerships and capital to accelerate growth.

Santiago Garcia

Principal

Alisa Smith

Director of Venture Services

6 past transactions

Nichefire

Seed Round in 2025
Nichefire is an AI-powered marketing analytics company that develops a predictive cultural intelligence platform. The platform helps businesses activate and interpret online brand and consumer interactions to inform decision making. It uses artificial intelligence to gather and analyze social metrics, brand tactics, and consumer sentiment, and to optimize media channels for marketing and competitive insight. The system collects, sorts, and categorizes millions of posts, comments, and reactions in seconds, enabling the identification of emerging consumer trends and opportunities for growth.

Cloverleaf.me

Series A in 2024
Cloverleaf LLC offers a visualization and scenario-planning platform designed to enhance team management and employee development. Founded in 2015 and based in Covington, Kentucky, the platform analyzes employee data to provide insights into team dynamics by cross-mapping personality traits, skills, and organizational culture. This enables users, including agile practitioners, project managers, and human resource professionals, to position team members effectively, improve communication, and identify suitable candidates to boost productivity. Additionally, Cloverleaf's automated coaching features deliver personalized nudges through commonly used tools like Google Workspace, Microsoft Outlook, and Slack, fostering collaboration and performance improvements within teams.

Enable Injections

Series C in 2022
Enable Injections designs and manufactures wearable devices that deliver injectable drugs directly into the subcutaneous tissue. The system accepts standard vials, syringes, or cartridges, automatically reconstitutes lyophilized solutions, warms the drug, and injects high‑viscosity or high‑volume payloads up to 20 ml. Users place the device on the skin, press a central button, and monitor delivery progress through a viewing window before disposing of the single‑use injector. The company also offers transfer systems for partial or multi‑vial filling and a Bluetooth‑enabled version that can connect to smartphones. Founded in 2010, the company is headquartered in Cincinnati, Ohio, and targets a growing market for self‑administration of biologics and other therapeutics.

Struxtion

Seed Round in 2021
Struxtion offers an online financing platform tailored for underserved commercial construction contractors. The platform aims to maintain the financial health of these contractors by providing cost-effective working capital solutions. It collects and analyzes project-related information to deliver optimal pricing, ultimately empowering contractors with the necessary financial support to thrive in their projects.

Enable Injections

Series B in 2018
Enable Injections designs and manufactures wearable devices that deliver injectable drugs directly into the subcutaneous tissue. The system accepts standard vials, syringes, or cartridges, automatically reconstitutes lyophilized solutions, warms the drug, and injects high‑viscosity or high‑volume payloads up to 20 ml. Users place the device on the skin, press a central button, and monitor delivery progress through a viewing window before disposing of the single‑use injector. The company also offers transfer systems for partial or multi‑vial filling and a Bluetooth‑enabled version that can connect to smartphones. Founded in 2010, the company is headquartered in Cincinnati, Ohio, and targets a growing market for self‑administration of biologics and other therapeutics.

Enable Injections

Series A in 2016
Enable Injections designs and manufactures wearable devices that deliver injectable drugs directly into the subcutaneous tissue. The system accepts standard vials, syringes, or cartridges, automatically reconstitutes lyophilized solutions, warms the drug, and injects high‑viscosity or high‑volume payloads up to 20 ml. Users place the device on the skin, press a central button, and monitor delivery progress through a viewing window before disposing of the single‑use injector. The company also offers transfer systems for partial or multi‑vial filling and a Bluetooth‑enabled version that can connect to smartphones. Founded in 2010, the company is headquartered in Cincinnati, Ohio, and targets a growing market for self‑administration of biologics and other therapeutics.
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