Connecticut Innovations

Swanston Labs builds data-driven solutions aimed at disrupting the convergence of media, entertainment, technology, and commerce. The company focuses on leveraging innovative technologies to address the $7 trillion global leisure spending market. Swanston Labs operates under the Swanston Organization, which also includes Swanston Family Ventures and Swanston Philanthropy, collectively advancing the mission of innovation and inclusion.

Normunity is a biotechnology company focused on developing precision immuno-oncology medicines, specifically a new class known as immune normalizers. These medicines aim to target novel mechanisms that enhance the body’s natural immune response against cancer. In collaboration with the lab of Dr. Lieping Chen at Yale School of Medicine, Normunity is researching newly-discovered mechanisms of immune disruption in cancer, utilizing proprietary discovery platforms to explore the intricate interactions between cancer and the immune system. The company is advancing a pipeline of immune normalizers, which includes initial drug programs designed to address the exclusion of T-cells from immune-sensitive tumors and other factors that impede normal immune function in cancer. Normunity operates from locations in Boston, Massachusetts, and West Haven, Connecticut.

VeraDermics is a dermatology company focused on developing innovative solutions for skin conditions, particularly warts. The company has created a dissolvable microneedle patch that delivers immunotherapy painlessly, stimulating the body's immune response to combat the wart virus. This patch is designed to be applied like a bandage and remains on the skin for less than an hour. During this time, the microneedles, made from immune stimulators embedded in a polymer matrix, dissolve and are implanted into the skin. After the adhesive backing is removed, the microneedles continue to dissolve over the following weeks, releasing immune stimulators directly into the wart. This method not only provides a pain-free treatment option but also simplifies the administration process for medical practitioners and enhances patient comfort.

Nimbus Power Systems focuses on creating a cleaner environment by designing and integrating zero-emission fuel cell systems specifically for heavy-duty markets. The company specializes in advanced cell technology, offering one-to-one replacements for diesel engines. Its innovative architecture enhances fuel cell performance and eliminates the need for a DC/DC converter. This enables clients to utilize hydrogen fuel cells that do not emit harmful pollutants, contributing to a sustainable energy future.

CREW Carbon focuses on the removal of greenhouse gas emissions from wastewater through engineered enhanced weathering. The company's technology harnesses the natural properties of minerals to effectively treat both municipal and industrial wastewater while permanently storing carbon dioxide. Operating in the environmental services sector, CREW Carbon is dedicated to greenhouse gas management and carbon removal, striving to contribute positively to environmental sustainability. Its innovative climate technology solutions are designed to assist businesses and governments in achieving their climate objectives.

GoodSAM is a food and beverages company specializing in snack and food products made from natural ingredients. It operates a chocolate brand that focuses on manufacturing cocoa products derived from regenerative farming practices. The company offers a range of items, including coffee, nuts, fruits, and seeds, as well as a line of sugar-free, vegan, and keto-friendly chocolate products. This line features chocolate bars, chocolate chips, and chocolate-coated nuts that incorporate allulose, a natural low-calorie sweetener sourced from dates and figs. GoodSAM aims to provide healthy, sustainable, and farmer-friendly chocolate options to its customers.

ampUp is a Silicon Valley-based company that specializes in electric vehicle (EV) charging solutions. It has developed a software platform that facilitates a reservable charging network, connecting drivers, hosts, and fleets to make EV charging more accessible and efficient. The platform allows businesses and property owners to manage multiple charging stations seamlessly, promoting a peer-to-peer network that enables users to monetize their chargers. By listing their charging stations on ampUp's network, customers can earn revenue while contributing to broader electrification efforts in their communities. Overall, ampUp aims to simplify the charging experience and support the growing demand for electric vehicle infrastructure.

Air Company is a carbon utilization firm focused on transforming carbon dioxide (CO2) captured from the atmosphere into sustainable consumer and industrial products. Utilizing its patented Carbon Conversion Reactor, which mimics photosynthesis, the company effectively converts CO2, water, and renewable energy into carbon-negative alcohols and fuels. Among its product offerings are AIR Vodka, AIR Hand Sanitizer, and AIR Eau de Parfum. The company is also advancing the development of CO2-derived sustainable aviation fuel (SAF), which will be certified by recognized sustainability organizations. With $40 million in venture capital funding, Air Company has received numerous accolades, including TIME Best Inventions and the Keeling Curve Prize, highlighting its innovative approach to carbon technologies. Through its initiatives, Air Company aims to contribute significantly to reducing greenhouse gas emissions and promoting a regenerative future aligned with nature.

Oxylus Energy focuses on innovative carbon utilization technology aimed at producing sustainable e-fuels from captured carbon dioxide. By employing a proprietary electrochemical process, the company converts CO2 into methanol, a clean-burning and versatile fuel. This approach not only provides a valuable waste product transformation but also supports the industrial sector in reducing dependence on fossil fuels, contributing to significant carbon reductions. Oxylus Energy is committed to making carbon capture and conversion competitive, scalable, and sustainable, ultimately promoting a decarbonized future.

Halda Therapeutics is a research-stage drug discovery company focused on developing next-generation precision medicines. The company utilizes a novel therapeutic modality aimed at creating treatments that can address various disease states. By modifying disease-causing pathways, Halda Therapeutics seeks to enable healthcare providers to offer tailored therapies to patients, enhancing the effectiveness of treatment based on individual patient needs.

Aware Recovery Care is a healthcare company that specializes in in-home addiction treatment services, employing a unique model designed to assist individuals, particularly young adults, struggling with substance use disorders. The company provides a comprehensive range of home-based care options, including in-home withdrawal management, medication-assisted treatment, individual and family therapy, and integrated medical and behavioral healthcare. This innovative approach allows patients to seek recovery in a familiar environment, enhancing their overall health and wellness. By transforming the home into a supportive treatment center, Aware Recovery Care delivers collaborative care that incorporates lived experiences, ensuring that individuals receive effective and personalized support on their journey to recovery.

Encapsulate specializes in automated tumor-on-a-chip technology, which allows for the growth and preservation of cancer cells outside the body. This innovative approach enables the creation of micro tumors from patients' cancer cells, facilitating the assessment of how these cells respond to various chemotherapy and biotherapy drugs. By evaluating the efficacy of treatments on an individualized basis, Encapsulate's technology aids oncologists in determining effective personalized treatment regimens for cancer patients, starting from the initial diagnosis. This method enhances the ability to tailor cancer therapies to the specific needs of each patient, thereby improving treatment outcomes.

Quantum Circuits, Inc. specializes in the development and manufacture of quantum computers utilizing superconducting devices. Founded in 2015 and located in New Haven, Connecticut, the company aims to innovate in the field of quantum computing by delivering full-stack systems that efficiently scale. Led by Dr. Robert Schoelkopf, a prominent figure in quantum science, Quantum Circuits employs a unique dual-rail quantum qubit design that incorporates built-in hardware error detection and conversion. This approach allows for a highly scalable error-corrected system, requiring significantly fewer physical qubits per logical qubit and providing a more efficient pathway to fault-tolerant quantum computing. By focusing on solid-state quantum bits, the company enables clients to perform error-free computations, thereby accelerating research and advancing the practical applications of quantum technology.

Manifest Technologies advances AI-powered computational neuroimaging system that quantifies neural and symptom data.

Conduce Health is a healthcare technology company focused on providing a comprehensive solution for multi-specialty value-based care. The company operates a platform designed to connect risk-bearing entities with specialists, addressing the challenges associated with specialty care risks. By offering downside protection on these risks, Conduce Health streamlines the contracting process for participation in value-based care, increases patient volume, and facilitates the matching of patients with optimal specialists. This approach aims to promote healthier lives through personalized care and proactive management of well-being, ultimately enhancing the efficiency and effectiveness of healthcare delivery.

DeepLook Medical develops advanced medical imaging software aimed at enhancing the detection of early breast cancer in mammograms. Utilizing shape-recognition technology, the software extracts and analyzes data from radiological images, particularly focusing on dense breast tissue where critical details may be obscured. By revealing radiomic features that reflect tissue morphology, the software helps physicians identify subtle indicators of breast cancer that are often undetectable by the human eye. This capability not only improves diagnostic accuracy but also reduces the likelihood of unnecessary surgical interventions by minimizing false positives in mammography results. Additionally, DeepLook Medical offers a phenotype database for breast cancer morphology, which is currently available for research purposes.

Nest Collaborative operates a virtual lactation support platform that connects parents and parents-to-be with board-certified lactation consultants. Accessible year-round, the service focuses on preventive care to enhance breastfeeding success by addressing the unique barriers mothers face, including physiological, emotional, and societal challenges. Through education, guidance, and practical support, Nest Collaborative aims to extend the duration of breastfeeding. The platform provides a comprehensive range of services, including prenatal planning and ongoing support, allowing mothers to easily schedule consultations online without the need for co-pays. By combining evidence-based interventions with accessible care, Nest Collaborative seeks to improve overall maternal and infant health outcomes.

Vita Health operates an online mental health care platform focused on providing high-quality treatment for adolescents and transitional age youth. The platform enables patients to receive quick and accessible care from licensed therapists through telehealth services. It addresses various mental health challenges, including anxiety, depression, and suicidal ideation, ensuring that young individuals can conveniently access the support they need from the comfort of their homes.

IntelliBoard, Inc. is a developer of a learning analytics platform focused on delivering insights and reporting services to educational institutions and corporate clients. Founded in 2015 and based in Monroe, Connecticut, IntelliBoard's platform integrates with various Learning Management Systems (LMS) to provide comprehensive data analysis tools. These tools enable faculty and management to access real-time data on learner engagement, performance, and the effectiveness of educational content. By presenting statistical data in an accessible format, including charts and formatted reports, IntelliBoard helps institutions make informed decisions, improve learning outcomes, and enhance operational efficiency. The company's mission is to empower clients to achieve their educational goals and maximize the return on their e-learning investments.

Cambium Carbon is an early-stage social enterprise focused on addressing climate change through innovative reforestation and urban wood reuse initiatives. The company collaborates with cities and various public and private partners to salvage fallen city trees that would otherwise end up in landfills. By transforming this wood waste into valuable resources, Cambium Carbon establishes reforestation hubs that create a circular economy for urban forests. These hubs not only generate revenue to support tree planting and maintenance projects but also foster sustainable job creation and contribute to the development of resilient urban environments. Through its efforts, Cambium Carbon aims to implement systems-level natural climate solutions that benefit both the environment and local communities.

Summer offers comprehensive property management services focused on vacation homes. The company operates a homeownership platform designed to assist clients in purchasing second homes and renting them out. By combining a rent-to-own program with short-term rental options, Summer aims to lower both the initial investment and ongoing costs associated with owning a second home. This approach simplifies the process, minimizing bureaucratic hurdles and allowing users to either move into ready-to-live-in homes or select their preferred second home.

Slooh, LLC, founded in 2003 and based in Washington Depot, Connecticut, offers an innovative platform for public engagement in astronomy by providing online access to robotic telescopes located in various observatories worldwide. The company connects these telescopes to the internet, allowing users to view celestial events in real-time and participate in astronomical discoveries. Slooh has developed partnerships with institutions such as NASA and the Institute of Astrophysics of the Canary Islands, enhancing its credibility in the field. Through its automated observatories, Slooh has facilitated the capture of millions of celestial images and has broadcast live events like eclipses and asteroid observations, featuring expert narration. The platform is geared towards making astronomy accessible and affordable, particularly for educational institutions, enabling students and the public to explore the universe collaboratively with guidance from astronomy educators.

Anonybit develops a decentralized framework aimed at enhancing compliance, protecting identity, and securing personal assets. The company specializes in encrypting sensitive information such as biometrics and private keys, distributing this data across a peer-to-peer network of nodes. Anonybit employs patented technologies, including multi-party computing and zero-knowledge proofs, to facilitate secure matching functions in a decentralized environment. Its flagship product, the Genie, serves as an integrated identity management platform designed with privacy in mind. This platform streamlines the entire lifecycle of digital identity, from onboarding to authentication, effectively closing vulnerabilities that could be exploited by attackers and allowing users to safeguard their online identities.

Modifi Biosciences specializes in direct DNA modification and the creation of innovative cancer therapeutics. The company's primary focus is on altering tumor DNA in a way that makes cancer cells irreparable while preserving healthy cells. This distinctive methodology allows researchers to challenge and transform traditional approaches to oncology drug development. By exploiting DNA defects across various cancer types, Modifi Biosciences aims to provide effective treatments that target the underlying genetic issues in tumors, thereby advancing the field of cancer therapeutics.

Raise Green is a financial technology company focused on promoting a sustainable future through equity crowdfunding. The company provides a platform that enables everyday individuals to invest in clean energy and climate solution projects, thereby democratizing access to renewable energy ownership. By facilitating community-driven project finance, Raise Green empowers community leaders to develop their own clean energy initiatives, such as community solar projects, allowing them to benefit from shared ownership. This approach not only helps combat climate change but also addresses income inequality by creating investment opportunities that are accessible to a wider audience. Through its efforts, Raise Green aims to enhance community resilience and support the transition to a decarbonized economy.

Oova Inc. is a fertility diagnostic company based in New York that specializes in developing personalized fertility testing solutions. Founded in 2017, Oova spun out from Mount Sinai Hospital and utilizes patent-pending biochemistry and artificial intelligence to analyze hormonal levels in women's urine. The company's innovative paper-based testing strips measure key hormones, such as luteinizing hormone and progesterone, allowing women to manage their menstrual cycles, assess fertility, and monitor reproductive health conditions like polycystic ovary syndrome (PCOS). By facilitating daily urine sample collection and offering real-time insights through a mobile application, Oova supports women in achieving their conception goals while seamlessly integrating into their daily lives.

Driver Technologies Inc. is a New York-based company that specializes in mobile application software focused on enhancing road safety. Founded in 2017, the company offers a hardware-free app that allows users to video record their trips while providing real-time alerts about potential hazards, such as the risk of colliding with other vehicles or pedestrians, lane drifting, and drowsiness. The app incorporates voice control features, facilitating safe access to entertainment, news, and navigation services without requiring physical interaction. Additionally, Driver Technologies aims to help users document their driving experiences, which can be useful for insurance purposes and improving overall safety on the road.

2045 Studio is a members-only network aimed at influential professionals of color, which collaborates with corporations to foster employee belonging, retention, and promotion. The organization develops a community platform that assists users in identifying new members within their companies, supporting both corporate and individual needs. Its B2B offerings focus on helping organizations cultivate inclusive leadership, while the B2C segment allows individuals to join curated networks centered around industry-specific groups. By creating spaces for individuals with shared lived experiences, 2045 Studio facilitates personal and professional growth, enabling meaningful connections among its members.

Inbox Health Corp. is a digital healthcare company based in New Haven, Connecticut, founded in 2014. It specializes in developing a patient communication platform aimed at medical billers in the United States. The Inbox Health platform automates the patient communication process through bi-directional correspondence and utilizes proprietary algorithms, machine learning, and artificial intelligence. This enables patients to better understand their medical bills and access various payment options. By analyzing a wide range of data points across its customer base, the platform allows billers to personalize the billing, payment, and communication experiences for each patient, ultimately enhancing patient collections and overall satisfaction. The company's mission is to reduce administrative waste in healthcare by streamlining the billing and payment experience for patients.

RNAConnect provides enzymatic tools for visualizing and manipulating RNA.

Bright Feeds is a company focused on food waste recycling, utilizing artificial intelligence and drying technology to convert food waste into animal feed. The company addresses pressing issues such as climate change and global food insecurity by offering a service that diverts unwanted food from landfills. By transforming this waste into a nutrient-rich alternative to traditional feed sources like soy and corn, Bright Feeds helps businesses achieve their sustainability objectives while enhancing profit margins. This innovative approach not only reduces food waste but also provides a valuable resource for the animal agriculture industry.

ReferWell operates a cloud-based platform that addresses the challenges associated with care transitions in healthcare. By connecting providers into Virtually Integrated Networks, ReferWell enhances visibility and coordination throughout the patient journey, ensuring efficient communication among providers and payers. The platform enables healthcare organizations to guide patients toward high-quality providers, thereby improving patient compliance, reducing leakage, and closing care gaps. Additionally, ReferWell's comprehensive services streamline referrals, facilitate point-of-care appointment scheduling, and support care teams with features such as provider directory management, eConsult, and telehealth capabilities. This holistic approach not only enhances patient experiences and outcomes but also aids clients in increasing revenue and improving healthcare metrics.

Bags is a loan discovery and management platform, built by and for the culture.

CINCH has created the first end-to-end real estate transaction ecosystem, providing agents and brokers everything they need to get deals done within a single application.

Peer Robotics is a company focused on developing collaborative mobile robotics aimed at enhancing material handling for small and medium-sized manufacturers. The company's robots are designed to work alongside humans, adapting to their actions in real-time to improve efficiency. These versatile mobile robots facilitate various tasks, including material movement, packaging, sorting, and visual inspection within warehousing, manufacturing, and assembly environments. By bridging the gap between human and robotic collaboration, Peer Robotics enables operators to optimize workflows and ensure timely delivery of goods, ultimately improving operational efficiency.

Aceiss is a developer of a compliance monitoring platform that enhances access security by providing visibility and insights into user access. The company's technology seamlessly integrates with existing applications and security infrastructure, allowing organizations to identify anomalous behavior and monitor privileged accounts. This capability enables businesses to anticipate potential security threats and take proactive measures to protect their sensitive information. By delivering immediate insights upon integration, Aceiss helps organizations strengthen their security posture and ensure compliance with regulatory requirements.

Modifi Biosciences specializes in direct DNA modification and the creation of innovative cancer therapeutics. The company's primary focus is on altering tumor DNA in a way that makes cancer cells irreparable while preserving healthy cells. This distinctive methodology allows researchers to challenge and transform traditional approaches to oncology drug development. By exploiting DNA defects across various cancer types, Modifi Biosciences aims to provide effective treatments that target the underlying genetic issues in tumors, thereby advancing the field of cancer therapeutics.

Noteworthy AI specializes in enhancing the management and evaluation of electric distribution grids through advanced technology. The company provides fleet-mounted smart cameras that capture critical data during routine vehicle operations. This data is processed by an artificial intelligence platform that monitors equipment conditions, identifies defects, and supports utilities in improving the reliability, safety, and efficiency of their operations. Noteworthy's solutions also facilitate various applications, including asset inspection, vegetation management, joint use compliance, and lighting audits, while effectively lowering operational and maintenance costs for electric utility companies.

FinTron is a fintech company that offers investment and banking solutions tailored for the mobile generation, particularly targeting young post-college graduates. The platform provides users with curated investment portfolios and educational resources, helping them build a strong foundation for investing. Additionally, FinTron features a business-to-business embedded wealth technology system that enhances financial freedom by consolidating essential financial data. Users can track their debt, savings, and investment accounts through a single application, allowing for streamlined access to vital information and updates regarding their financial and investment activities.

Torigen Pharmaceuticals is dedicated to advancing cancer care for companion animals through innovative treatment options. Founded in 2013 and based in Farmington, Connecticut, the company focuses on developing immunotherapy solutions, particularly an experimental autologous cancer vaccine. This vaccine aims to activate the immune system to target specific tumor-associated antigens present on cancer cells, allowing for more effective detection and treatment of tumors. By providing alternatives to traditional, invasive methods such as surgeries and chemotherapy, Torigen seeks to improve the quality of life for pets facing cancer. The company builds on years of scientific research and is committed to pushing the boundaries of veterinary oncology.

PlazMod Technology specializes in developing and implementing innovative battery manufacturing processes. The company focuses on a groundbreaking materials processing technology designed to facilitate the production of structured materials systems. This technology aims to support industries worldwide in transitioning their energy systems towards greater electrification, contributing to a more sustainable global energy landscape.

Upswing Health is a digital sports medicine platform that aims to revolutionize orthopedic care for athletes. By utilizing artificial intelligence and medical expertise, Upswing Health offers a community-powered solution that helps athletes identify and manage injuries related to various body parts, including the ankle, knee, elbow, and shoulder. The platform is designed to address low- and medium-acuity orthopedic issues, coordinating care between Athletic Trainers and Orthopedic Specialists. This innovative care delivery model not only reduces costs but also enhances patient outcomes across the musculoskeletal care continuum, ensuring that athletes receive convenient access to quality information and guidance on their recovery journey.

Encapsulate specializes in automated tumor-on-a-chip technology, which allows for the growth and preservation of cancer cells outside the body. This innovative approach enables the creation of micro tumors from patients' cancer cells, facilitating the assessment of how these cells respond to various chemotherapy and biotherapy drugs. By evaluating the efficacy of treatments on an individualized basis, Encapsulate's technology aids oncologists in determining effective personalized treatment regimens for cancer patients, starting from the initial diagnosis. This method enhances the ability to tailor cancer therapies to the specific needs of each patient, thereby improving treatment outcomes.

CoreChain Technologies operates a business-to-business payments network that utilizes blockchain technology to enhance the efficiency and security of transactions. The company's platform is designed to facilitate the exchange of funds and transaction data between businesses, thereby reducing the manual processes that can lead to errors and reconciliation issues. By automating these exchanges within a secure environment, CoreChain Technologies aims to help businesses streamline their B2B payments and unlock working capital that may be tied up in traditional payment processes.

Source Defense Ltd. specializes in website security software aimed at preventing attacks originating from third-party sources. Established in 2014 and headquartered in Rosh-ha’ayin, Israel, with additional offices in Beer-Sheva and Stamford, Connecticut, the company offers a real-time Software-as-a-Service platform. This platform empowers site owners to set and enforce permissions, receive real-time alerts, and monitor the behavior of third-party vendors on their sites. Source Defense provides tailored solutions for various sectors, including financial institutions, insurance companies, e-commerce, and content publishers. By focusing on prevention rather than detection, Source Defense helps organizations eliminate security concerns associated with third-party integrations, ultimately allowing them to concentrate on enhancing revenue opportunities while ensuring the safety and performance of their websites.

Covr Financial Technologies, Inc. is a digitally enabled brokerage general agency based in Boise, Idaho, founded in 2013. The company specializes in providing life, long-term care, and disability insurance solutions tailored for financial institutions, advisors, and their clients. Covr offers a suite of digital platforms, including Covr Advisor, which helps financial advisors meet their clients' insurance needs by selecting appropriate products; Covr Consumer, which allows banks and credit unions to sell life insurance directly to customers; and Covr Insights, a tool for managing and analyzing existing life insurance policies. The company serves over 24,000 financial advisors and 13 million customers across 30 financial institutions, facilitating a simplified and efficient sales process for life insurance products.

1906 is a cannabis company founded in 2016 that focuses on creating fast-acting, functional products aimed at enhancing wellness. Named after the year cannabis was last widely used as medicine, 1906 aims to reintegrate the plant into society as a health tool rather than simply for recreation. The company differentiates itself in the cannabis market by offering premium products that address specific wellness needs such as sleep, focus, relaxation, energy, and intimacy. Unlike many brands that prioritize high THC content, 1906 targets health-conscious consumers seeking predictable effects. Its proprietary fast-acting technology allows products to take effect within 20 minutes, significantly quicker than typical edibles. This emphasis on consistent dosing and rapid onset makes 1906 appealing to a diverse customer base, including professionals and health enthusiasts. With a direct-to-consumer platform launched in 2023, the company is expanding its reach across legalized states. As consumer demand for wellness-oriented cannabis products grows, 1906 is well-positioned for sustained success in the evolving cannabis landscape.

Nest Collaborative operates a virtual lactation support platform that connects parents and parents-to-be with board-certified lactation consultants. Accessible year-round, the service focuses on preventive care to enhance breastfeeding success by addressing the unique barriers mothers face, including physiological, emotional, and societal challenges. Through education, guidance, and practical support, Nest Collaborative aims to extend the duration of breastfeeding. The platform provides a comprehensive range of services, including prenatal planning and ongoing support, allowing mothers to easily schedule consultations online without the need for co-pays. By combining evidence-based interventions with accessible care, Nest Collaborative seeks to improve overall maternal and infant health outcomes.

NourishedRx is a provider of personalized food solutions aimed at health plan members and patients with diet-sensitive chronic health conditions, particularly those experiencing nutrition insecurity. Founded in 2019 in Stamford, Connecticut, the company delivers customized meal plans and meal prep kits tailored to individual eating habits. In addition to food solutions, NourishedRx offers educational resources and support to promote lasting behavior change, ultimately enhancing member engagement and satisfaction. The company's approach is designed to improve clinical outcomes and deliver significant cost savings for both individuals and healthcare systems.

Wellinks, Inc., established in 2014 and headquartered in New Haven, Connecticut, specializes in wearable health technology for orthotics and prosthetics. The company develops a smart strap for scoliosis braces, tracking wear duration and tightness, and providing real-time data to patients, parents, and doctors. This information enables better-informed treatment decisions, enhances patient motivation, and facilitates remote patient monitoring between clinical visits.

VeraDermics is a dermatology company focused on developing innovative solutions for skin conditions, particularly warts. The company has created a dissolvable microneedle patch that delivers immunotherapy painlessly, stimulating the body's immune response to combat the wart virus. This patch is designed to be applied like a bandage and remains on the skin for less than an hour. During this time, the microneedles, made from immune stimulators embedded in a polymer matrix, dissolve and are implanted into the skin. After the adhesive backing is removed, the microneedles continue to dissolve over the following weeks, releasing immune stimulators directly into the wart. This method not only provides a pain-free treatment option but also simplifies the administration process for medical practitioners and enhances patient comfort.

FuturesTHRIVE specializes in an AI-driven platform aimed at enhancing pediatric mental health care. The company's technology leverages artificial intelligence, sentiment analysis, and machine learning to establish a mental health baseline, enabling healthcare providers and families to gain insights into a child's mental health characteristics. This innovative approach facilitates the early identification of mental health conditions and risk factors among children, thereby supporting timely interventions. By focusing on the unique mental health needs of youth, FuturesTHRIVE addresses the growing concerns surrounding children's mental well-being and promotes proactive monitoring and support.

Lessonbee Inc. is an online learning platform focused on health and wellness education for students in grades K-12. Founded in 2017 and headquartered in Mount Vernon, New York, the company provides a cloud-based reflective learning system that includes adaptive lessons and a shared content library. This platform allows educators to access current and relevant educational content, manage student assignments, and foster engagement through regular reflection. Lessonbee emphasizes culturally responsive and medically accurate health education, equipping students with the knowledge and skills to promote healthy living. Additionally, it utilizes proprietary analytics to assess student health goals and school climate, recommending tailored content from a diverse library of self-paced classes, adaptive courses, and video-based lessons that align with state and national health education standards. The platform aims to enhance personalized health education and support social-emotional learning for students both at home and in school.

Owl's Brew, founded in 2013 by tea sommelier Jennie Ripps and Maria Littlefield, specializes in all-natural, loose leaf tea blends crafted in New York City. The company offers two primary product lines: Owl's Brew Mixer, a selection of tea-based craft cocktail mixers, and Owl's Brew Boozy Tea, which combines brewed tea with alcohol. The beverages are made from whole tea leaves, fruits, spices, and herbs, ensuring that no artificial flavors are added. This commitment to quality allows consumers to enjoy a variety of flavored tea products that are both refreshing and unique.

DiA Imaging Analysis Ltd. specializes in AI-driven ultrasound analysis technology aimed at enhancing cardiac function diagnostics. Established in 2009 and based in Beersheba, Israel, the company provides a suite of automated tools, including LVivo EF for ejection fraction evaluation, LVivo RV for right ventricle analysis, and LVivo Strain for assessing myocardial strain. These solutions address common challenges faced by clinicians, such as obtaining optimal images and accurately analyzing them for clinical abnormalities. DiA's products, which can be integrated into any ultrasound device or healthcare IT system, also include LVivo SAX for detecting coronary heart disease and LVivo Mobile for mobile ultrasound analysis. The company holds regulatory clearances for its cardiac toolbox and serves a global user base, reflecting its commitment to making ultrasound analysis smarter and more accessible.

Shelf is a knowledge management platform aimed at improving the efficiency of distributed teams by streamlining the process of finding and managing organizational knowledge. The platform addresses the challenges of content disorganization prevalent in remote work environments, where teams may face difficulties in accessing critical information. By leveraging natural language processing, Shelf enhances search capabilities, enabling users to quickly locate the answers they need. The platform integrates knowledge management best practices developed in collaboration with experts, ensuring that users can manage content effectively while reducing the time spent on knowledge retrieval and maintenance. Shelf's mission is to empower teams globally to learn, share, and succeed without the burdens of excessive work or inefficient tools, ultimately reimagining the library concept for the modern workplace.

CoreChain Technologies operates a business-to-business payments network that utilizes blockchain technology to enhance the efficiency and security of transactions. The company's platform is designed to facilitate the exchange of funds and transaction data between businesses, thereby reducing the manual processes that can lead to errors and reconciliation issues. By automating these exchanges within a secure environment, CoreChain Technologies aims to help businesses streamline their B2B payments and unlock working capital that may be tied up in traditional payment processes.

BEKhealth specializes in clinical research software that enhances the efficiency of clinical trials and observational studies. The company utilizes an AI-powered platform for chart abstraction and patient matching, which enables organizations to gain deeper insights into their patient populations. By extracting structured and unstructured data from electronic medical records, BEKhealth's technology captures three times more trial criteria, thereby facilitating faster feasibility assessments, optimizing site selection, and identifying clinically qualified participants more effectively. This approach not only accelerates timelines but also aims to increase the number of protocol-eligible candidates significantly, leading to enhanced enrollment processes and reduced costs for clients.

Triax Technologies offers a connected Internet of Things (IoT) worksite platform tailored for construction, energy, and heavy industrial sectors. The company focuses on enhancing safety, efficiency, and visibility in challenging work environments through innovative technology and real-time data analytics. Its flagship product, the Spot-r system, connects workers, equipment, and operations using a minimal infrastructure network, wearable devices, and a cloud-based dashboard. This system provides real-time insights into site access, worker and equipment locations, safety incidents, and emergency procedures, enabling firms to make informed decisions and streamline operations. In response to the COVID-19 pandemic, Triax launched Proximity Trace, an IoT solution designed to assist in workplace safety by offering proximity distancing alerts and contact tracing. This initiative aims to protect essential workers while facilitating their safe return to work in compliance with social distancing guidelines. Overall, Triax Technologies is committed to transforming worksite management through intelligent technology and actionable insights.

Lumeda Inc. is a biotechnology company focused on developing advanced photonic tools for intraoperative photodynamic therapy (PDT) to treat lung cancer. Founded in 2020 and based in Rocky Hill, Connecticut, the company aims to enhance the efficacy and ease of PDT procedures. Lumeda's innovative solutions include light delivery instrumentation and proprietary software that automates the delivery of light to targeted tumors with precise dosimetry profiles. By integrating advanced photonics with artificial intelligence, Lumeda's technology improves treatment planning and performance, allowing for a streamlined and reliable intraoperative PDT procedure. This approach not only addresses tumor margins during conventional non-small cell lung cancer resections but also seeks to reduce post-operative recurrence and improve overall patient outcomes.

Inbox Health Corp. is a digital healthcare company based in New Haven, Connecticut, founded in 2014. It specializes in developing a patient communication platform aimed at medical billers in the United States. The Inbox Health platform automates the patient communication process through bi-directional correspondence and utilizes proprietary algorithms, machine learning, and artificial intelligence. This enables patients to better understand their medical bills and access various payment options. By analyzing a wide range of data points across its customer base, the platform allows billers to personalize the billing, payment, and communication experiences for each patient, ultimately enhancing patient collections and overall satisfaction. The company's mission is to reduce administrative waste in healthcare by streamlining the billing and payment experience for patients.

Enko Chem, Inc. is a biotechnology company based in Woburn, Massachusetts, that focuses on discovering and developing innovative small-molecule products designed to protect crops from pests and diseases. Founded in 2017, the company utilizes a proprietary technology platform that enables the rapid identification of safe and cost-effective solutions aimed at promoting sustainable food production. Through its efforts, Enko Chem seeks to address the challenges faced by farmers in maintaining crop health while ensuring environmental sustainability.

Artizan Biosciences, Inc. is a biotechnology company based in New Haven, Connecticut, founded in 2016. The company focuses on developing small molecule drugs aimed at treating serious diseases linked to intestinal inflammation. Utilizing its proprietary IgA-SEQ technology platform, Artizan distinguishes disease-driving bacteria within the intestinal microbiota. This innovative approach enables the development of precision therapeutics designed to address unmet medical needs in various conditions, including digestive disorders, obesity, autoimmune diseases, and disorders affecting the skin, lungs, and central nervous system. Through its research, Artizan aims to provide new and potentially curative treatment options for patients suffering from these diverse health challenges.

Leal Health, formerly known as Trialjectory, is an AI-powered platform focused on enhancing cancer care by facilitating connections between patients and suitable clinical trials. The company collaborates with patients, healthcare providers, and pharmaceutical firms to make advanced cancer treatments more accessible and to support patient-centric clinical trials. Utilizing self-reported clinical data, Leal's platform streamlines the search and enrollment process for cancer patients and their physicians, ensuring they can find appropriate treatment options effectively. Leal Health has gained recognition for its innovative approach, being named one of TIME's "The 100 Best Inventions of 2020" and receiving an honor in the AI and data category at Fast Company's "2021 World-Changing Ideas Awards."

Athena Therapeutics, LLC is a biotechnology company based in New Haven, Connecticut, focused on developing drugs that target defects in NAD metabolism associated with cancer. Established in 2018, the company employs innovative methods to identify and characterize altered states of NAD metabolism, allowing for the selective targeting of tumors while sparing normal tissues. Athena Therapeutics has assembled a team of researchers with expertise in NAD metabolism, including notable figures such as Dr. Emmanuel Burgos, who leads the internal discovery biology efforts. To enhance its research capabilities, the company has also formed a Scientific Advisory Board comprising experts in enzymology and oncology drug development, including Professor Vern Schramm and Dr. Leonard Post. This strategic approach positions Athena Therapeutics to advance its understanding of NAD pathways and develop effective cancer therapies.

Diameter Health, Inc. develops innovative software solutions aimed at enhancing data interoperability for healthcare organizations. The company's flagship product, Fusion, facilitates intelligent data exchange by normalizing and cleansing information from certified electronic health records (EHRs), thereby transforming it into clinically relevant data for point-of-care use and analytics. In addition to Fusion, Diameter Health offers various tools, including Data Dashboard, which provides instant data quality ratings and metrics for clinical document accuracy; Quality, which supports certified quality reporting of e-measures; and Payer Edition, designed for generating standard supplemental reporting data. Other offerings include Subscribe, which allows for automatic updates for specific patient populations, and a scalable Hosted Solution. Diameter Health serves a diverse clientele, including government agencies, health information exchanges, payers, healthcare IT vendors, life insurers, and health systems. Founded in 2013, the company operates from its offices in Farmington, Connecticut, and Wellesley, Massachusetts.

Alphina Therapeutics is a biotechnology company focused on developing innovative therapies for cancer patients by targeting NAD Metabolic Deficiencies (NMD). The company utilizes proprietary biomarkers and insights to create companion diagnostics that identify specific cancer patient subsets with NMD. By targeting multiple nodes in NAD synthesis pathways, Alphina aims to develop selective small molecules that can effectively treat tumors while minimizing impact on normal tissues. Their approach involves characterizing altered states of NAD metabolism, enabling the development of new drug classes tailored to address defects in NAD metabolism associated with cancer. The ultimate goal is to translate these advancements quickly into clinical applications for improved cancer treatment.

WRM Software develops business productivity applications aimed at enhancing operational efficiency and improving business processes. The company's offerings include specialized tools such as the storm manager and ops manager applications, which facilitate seamless connectivity between field and office operations. These applications are designed to be user-friendly, ensuring that all team members have access to the latest information at any time. WRM Software's solutions support emergency response operations and field service management, helping organizations streamline their management processes.

Azitra Inc. is a clinical-stage medical dermatology company based in Farmington, Connecticut, focused on developing microbiome-based therapeutics for skin diseases. Established in 2014, Azitra leverages its proprietary platform, which includes a microbial library of bacterial strains, to discover and create novel treatments for adverse skin conditions. The company's technology, developed in collaboration with researchers at Yale University and the Jackson Laboratory, is centered around a specific strain of the natural commensal bacteria Staphylococcus epidermidis. Additionally, Azitra employs artificial intelligence and machine learning to enhance the screening and prediction of therapeutic characteristics within its microbial library. By utilizing engineered proteins and live biotherapeutic products for topical application, Azitra aims to advance precision dermatology.

Point Pickup Technologies is a mobile app delivery platform that addresses on-demand, pre-scheduled, and recurring same-day delivery needs across various sectors. It offers a comprehensive solution for middle and last-mile deliveries, catering to a wide range of industries including big-box retail, grocery, liquor, and pharmaceuticals. The platform utilizes precise matching technology to connect delivery requests with suitable drivers, which can include everyday individuals with personal vehicles as well as professional commercial drivers. This enables businesses to efficiently deliver goods to their final destinations while providing real-time tracking of packages. Operating across all major markets in the United States, Point Pickup also prioritizes underserved secondary markets, enhancing accessibility for various businesses and consumers.

Biorez, Inc. is a medical device company specializing in the development of bioresorbable scaffold implants aimed at regenerating functional tissue in vivo. Founded in 2008 and based in New Haven, Connecticut, Biorez offers innovative products such as an off-the-shelf implant for anterior cruciate ligament (ACL) reconstruction, which eliminates the need for harvesting donor tissue and serves as a superior alternative to cadaver-based materials. The company's technology utilizes a degradable polymer, specifically PLLA, to create implants that stabilize surgical repairs and facilitate the body's natural tissue regeneration, thereby enhancing musculoskeletal outcomes. Among its product lineup is the L-C Ligament® and the biorez GRAFT™, an FDA-cleared device designed for soft tissue augmentation of the rotator cuff. By leveraging this technology, Biorez aims to accelerate patient recovery and improve surgical outcomes in orthopedic procedures.

IvyTech Design was founded with a mission to develop adjustable-angle orthopedic instruments that can distract, align, and compress bones more precisely than current tools. Our patented and patent-pending technology addresses key challenges in foot and spine procedures, which suffer from high complication rates (up to 20-25%), costly revision surgeries, and suboptimal patient outcomes. IvyTech Design’s instruments will enable surgeons to precisely angle bones, providing superior alignment and access in foot and spine operations. Surgeons, hospitals, and patients will all benefit from this technology, as we aim to lower complication and revision rates, reduce surgical times, and improve patient outcomes.

Shelf is a knowledge management platform aimed at improving the efficiency of distributed teams by streamlining the process of finding and managing organizational knowledge. The platform addresses the challenges of content disorganization prevalent in remote work environments, where teams may face difficulties in accessing critical information. By leveraging natural language processing, Shelf enhances search capabilities, enabling users to quickly locate the answers they need. The platform integrates knowledge management best practices developed in collaboration with experts, ensuring that users can manage content effectively while reducing the time spent on knowledge retrieval and maintenance. Shelf's mission is to empower teams globally to learn, share, and succeed without the burdens of excessive work or inefficient tools, ultimately reimagining the library concept for the modern workplace.

Encapsulate specializes in automated tumor-on-a-chip technology, which allows for the growth and preservation of cancer cells outside the body. This innovative approach enables the creation of micro tumors from patients' cancer cells, facilitating the assessment of how these cells respond to various chemotherapy and biotherapy drugs. By evaluating the efficacy of treatments on an individualized basis, Encapsulate's technology aids oncologists in determining effective personalized treatment regimens for cancer patients, starting from the initial diagnosis. This method enhances the ability to tailor cancer therapies to the specific needs of each patient, thereby improving treatment outcomes.

EyeControl is a pioneer in medical technology focused on innovative communication solutions for healthcare. The company has developed a unique device aimed at improving the quality of life for patients with locked-in syndrome, particularly those suffering from ALS. This device consists of a simple glass frame equipped with an infrared camera that connects to a compact computer. It translates the patients' blinks and eye movements into commands, which are then converted into speech through earphones and a speaker. By leveraging advanced technology, EyeControl addresses significant communication barriers, enabling patients to express their needs and preferences more effectively.

Voiceitt Ltd is a technology company based in Ramat Gan, Israel, founded in 2012. The company specializes in developing automatic speech recognition software aimed at enhancing communication for individuals with speech impairments and non-standard speech patterns. Voiceitt's innovative platform utilizes an AI-driven speech engine to interpret and translate distorted pronunciations into intelligible speech, thereby improving the quality of life and independence for users with motor, speech, and language disorders. Additionally, the software serves as a valuable communication tool for caregivers and family members, facilitating more effective interactions.

GeneDx is a company dedicated to providing personalized and actionable health insights that enhance diagnosis and treatment, ultimately improving health outcomes. Positioned at the intersection of diagnostics and data science, GeneDx combines decades of genomic expertise with the capability to interpret clinical data at scale. The company focuses on accelerating the application of genomic information and large-scale clinical data to establish precision medicine as a standard practice in healthcare. GeneDx leads the transformation of healthcare through its comprehensive exome and genome testing services, leveraging one of the largest rare disease data sets in the world. The business operates through two segments: GeneDx, which generates the majority of its revenue, and Legacy Sema4 diagnostics.

Enrich Therapeutics Inc. is a biotechnology company that specializes in developing innovative single-cell isolation technologies for life science research. The company offers LASUM, a technology that enables the selection and isolation of single cells under a microscope, applicable to various cell types, including suspension cells, adherent cells, and challenging tissue samples. This technology enhances scalability and affordability for critical applications such as antibody drug discovery, next-generation sequencing (NGS), and the development of adoptive cell therapies. Enrich Therapeutics also engages in phage display library engineering, affinity-on-demand binder selection, cell line development for CAR-T immunotherapy, B-cell isolation, and precision cell isolation for NGS analysis. Founded in 2018 and based in Worcester, Massachusetts, the company aims to advance the capabilities of life science research through its tailored solutions.

Simcha Therapeutics is a biopharmaceutical company focused on developing engineered cytokine immunotherapies for cancer treatment. Based in New Haven, Connecticut, the company employs directed evolution to create novel cytokines aimed at enhancing the immune system's ability to combat diseases. Its lead program, ST-067, is a designer IL-18 cytokine that has demonstrated significant antitumor activity in animal studies, both as a standalone treatment and in combination with anti-PD-1 checkpoint inhibitors. Founded in 2018, Simcha Therapeutics is dedicated to advancing innovative therapies that empower patients to effectively fight cancer.

Invixium Inc. is a Canadian company specializing in biometric solutions aimed at enhancing access control, workforce management, and visitor screening for various industries. Established in 2012 and headquartered in Markham, Canada, Invixium designs a range of innovative products, including the Ixm Mycro, Ixm Touch, IXM Titan, IXM Merge, and Ixm Sense, which cater to both residential and industrial environments. These products incorporate advanced technologies such as face recognition, fingerprint tracking, and temperature detection to ensure security and health in workplaces. Invixium's fully integrated hardware and software solutions provide valuable analytics that improve safety and productivity. With a management team boasting over 200 years of collective experience in the biometric access control sector, Invixium's products have been deployed in diverse sectors, including government, healthcare, and education, across more than 60 countries. The company's commitment to quality is reflected in its manufacturing process, with all products proudly made in Canada.

1touch.io is a developer of an AI-based platform focused on sustainable data discovery and management, addressing privacy, security, and data governance needs. The platform utilizes artificial intelligence and natural language processing to automate the discovery, mapping, and cataloging of sensitive data across an enterprise. By continuously analyzing network traffic and connected repository stores, 1touch.io can identify all elements that store, process, and share personal data, whether structured or unstructured. This capability extends to data in motion, at rest, and even data that may be unknown to organizations, allowing businesses to comprehensively understand their sensitive data usage across various repositories.

Covr Financial Technologies, Inc. is a digitally enabled brokerage general agency based in Boise, Idaho, founded in 2013. The company specializes in providing life, long-term care, and disability insurance solutions tailored for financial institutions, advisors, and their clients. Covr offers a suite of digital platforms, including Covr Advisor, which helps financial advisors meet their clients' insurance needs by selecting appropriate products; Covr Consumer, which allows banks and credit unions to sell life insurance directly to customers; and Covr Insights, a tool for managing and analyzing existing life insurance policies. The company serves over 24,000 financial advisors and 13 million customers across 30 financial institutions, facilitating a simplified and efficient sales process for life insurance products.

IntelliBoard, Inc. is a developer of a learning analytics platform focused on delivering insights and reporting services to educational institutions and corporate clients. Founded in 2015 and based in Monroe, Connecticut, IntelliBoard's platform integrates with various Learning Management Systems (LMS) to provide comprehensive data analysis tools. These tools enable faculty and management to access real-time data on learner engagement, performance, and the effectiveness of educational content. By presenting statistical data in an accessible format, including charts and formatted reports, IntelliBoard helps institutions make informed decisions, improve learning outcomes, and enhance operational efficiency. The company's mission is to empower clients to achieve their educational goals and maximize the return on their e-learning investments.

CytoVeris is a company focused on developing optical-based technologies to assist surgical oncologists in identifying and removing tumor tissue during cancer resection surgeries. Founded in 2018 by Alan Kersey in Farmington, Connecticut, CytoVeris aims to enhance the surgeon's ability to achieve clean margins, thereby improving patient outcomes. The company’s devices facilitate real-time assessment of tissue and generate molecular-specific information by detecting unique signatures created by cancer cells that alter cellular metabolic processes. This includes variations in lipids, proteins, and metabolites, which can be identified using their OncoMap system. By providing oncologists with critical information during surgery, CytoVeris seeks to reduce healthcare costs associated with repeat surgeries.

MindNest Health, Inc. is a Connecticut-based company founded in 2016 that develops a digital platform for parent training, enabling caregivers to implement clinically validated behavioral interventions for children with conditions such as ADHD, autism, and disruptive behaviors. The platform aims to promote children's development by providing evidence-based solutions that address behavioral health challenges, including anxiety and depression. MindNest Health's approach seeks to eliminate barriers parents face when seeking help, thereby enhancing access to care for their children and reducing stress for families. Additionally, the company is focused on decreasing the overall cost of care for employers and payers, with a vision of fostering an environment where children and families can thrive.

WAVE was created with a mission to end drowning, a leading cause of death in children and adults. Our product works with lifeguards and parents to detect drowning at the first sign of danger.

ReferWell operates a cloud-based platform that addresses the challenges associated with care transitions in healthcare. By connecting providers into Virtually Integrated Networks, ReferWell enhances visibility and coordination throughout the patient journey, ensuring efficient communication among providers and payers. The platform enables healthcare organizations to guide patients toward high-quality providers, thereby improving patient compliance, reducing leakage, and closing care gaps. Additionally, ReferWell's comprehensive services streamline referrals, facilitate point-of-care appointment scheduling, and support care teams with features such as provider directory management, eConsult, and telehealth capabilities. This holistic approach not only enhances patient experiences and outcomes but also aids clients in increasing revenue and improving healthcare metrics.

ProteoWise Inc., founded in 2018 and based in Branford, Connecticut, specializes in the development of innovative proteomics instruments. The company has created a unique 3-dimensional nanoscale protein capturing material that significantly enhances the analysis of proteins, enabling researchers to conduct experiments more easily and efficiently. ProteoWise's technology simplifies the traditional western blot method, providing a combination of high information content, high throughput, and low cost. This advancement is instrumental in driving the genomic revolution and supports the growing demands of proteomics research. The company was established by a team of experienced scientists from the Strittmatter Lab at Yale University, who bring a strong history of innovation to the field.

Inbox Health Corp. is a digital healthcare company based in New Haven, Connecticut, founded in 2014. It specializes in developing a patient communication platform aimed at medical billers in the United States. The Inbox Health platform automates the patient communication process through bi-directional correspondence and utilizes proprietary algorithms, machine learning, and artificial intelligence. This enables patients to better understand their medical bills and access various payment options. By analyzing a wide range of data points across its customer base, the platform allows billers to personalize the billing, payment, and communication experiences for each patient, ultimately enhancing patient collections and overall satisfaction. The company's mission is to reduce administrative waste in healthcare by streamlining the billing and payment experience for patients.

Aero Therapeutics specializes in creating medical devices aimed at addressing respiratory issues, particularly in low-resource environments. The company's innovative device is designed specifically for neonatal care, offering a solution that oxygenates, warms, humidifies, and sterilizes air prior to delivery. This all-in-one mobile enclosure provides an affordable and effective option for clinicians treating infants with respiratory challenges in settings where resources may be limited. By focusing on accessibility and functionality, Aero Therapeutics aims to improve patient outcomes in vulnerable populations.

Lessonbee Inc. is an online learning platform focused on health and wellness education for students in grades K-12. Founded in 2017 and headquartered in Mount Vernon, New York, the company provides a cloud-based reflective learning system that includes adaptive lessons and a shared content library. This platform allows educators to access current and relevant educational content, manage student assignments, and foster engagement through regular reflection. Lessonbee emphasizes culturally responsive and medically accurate health education, equipping students with the knowledge and skills to promote healthy living. Additionally, it utilizes proprietary analytics to assess student health goals and school climate, recommending tailored content from a diverse library of self-paced classes, adaptive courses, and video-based lessons that align with state and national health education standards. The platform aims to enhance personalized health education and support social-emotional learning for students both at home and in school.

P2 Science, Inc. is a bio-renewable chemistry company based in Woodbridge, Connecticut, specializing in the development and production of specialty chemicals derived from renewable feedstocks, such as vegetable oils. Founded in 2009 by a team that includes Yale scientists and an experienced chemical industry executive, the company focuses on creating high-value ingredients for flavors, fragrances, cosmetics, and other applications. P2 Science aims to provide sustainable alternatives to traditional petrochemical products, catering to diverse markets, including personal care, household cleaning, agriculture, and environmental remediation. Their innovative technology enables the conversion of renewable resources into cost-effective chemical solutions, addressing the increasing demand for greener options among major users in the specialty chemicals sector. The company also maintains a laboratory in New Haven, Connecticut, to support ongoing research and partnerships throughout the supply chain.

Enviro Power, LLC, founded in 2013 and based in Hartford, Connecticut, specializes in the development and marketing of innovative heating equipment for both residential and commercial applications. The company offers two main products: the Commercial SmartWatt Boiler, designed for light-commercial and high-end residential settings, and the Residential SmartWatt Boiler for home use. Enviro Power's SmartWatt Boiler technology platform not only meets heating requirements but also generates electricity at nearly zero cost, providing backup power and enhancing grid stability. This system allows building owners to potentially reduce utility bills while simultaneously lowering their carbon footprint and contributing to improved grid resiliency.

IsoPlexis is a life science technology company based in Branford, Connecticut, founded in 2013. It focuses on developing a single-cell detection system that identifies patient immune responses at the single-cell level. This innovative platform enables the assessment of therapeutic safety and efficacy, as well as the monitoring of disease progression. IsoPlexis specializes in cell-based proteomic systems and biomarkers, providing insights into functional protein biology and cellular signaling networks with high resolution. By offering these capabilities, the company aids in predicting patient responses to novel immunotherapies and cellular therapies, ultimately enhancing therapeutic development and informing clinical decisions.

Better Rhodes is a premium beverage platform specializing in 'Lo and No' alcoholic alternatives, providing a diverse range of alcohol-free spirits, beers, wines, mixers, soft drinks, and adult beverages. The company focuses on delivering high-quality, non-alcoholic options directly to consumers through a subscription model. With an emphasis on product development and go-to-market services, Better Rhodes curates a selection of beverages designed to meet the growing demand for premium, alcohol-free options, catering to health-conscious consumers seeking flavorful alternatives.

BioWave Corporation develops and distributes advanced pain-blocking technology that delivers therapeutic electrical signals to alleviate pain at its source. The company's range of products includes BioWavePENS, a percutaneous electrical nerve stimulation device designed for severe chronic, acute, and post-operative musculoskeletal and neuropathic pain; BioWavePRO, a comprehensive pain therapy system for various pain types; BioWaveHOME, which allows users to manage pain at home or while traveling; and BioWaveGO, an over-the-counter pain relief solution. The technology works by blocking the transmission of pain signals to the brain, providing relief comparable to chemical anesthetics but through electrical stimulation. BioWave serves a diverse clientele, including professional athletes, U.S. veterans, active military personnel, pain management specialists, and the general public. Founded in 1997 and headquartered in Norwalk, Connecticut, BioWave also offers accessories and disposables related to its pain relief devices.

Pineapple Tech Pty Ltd is a South African company that operates a peer-to-peer insurance platform, providing short-term insurance coverage to its members. Founded in 2017 and based in Johannesburg, the company allows users to pay and track their premiums online while selecting their preferred network for pooling. Pineapple aims to innovate the insurance experience by aligning incentives with users, offering transparency about premium usage, and returning any unused premiums to members. The platform simplifies the insurance process, enabling users to obtain coverage quickly, often in under 60 seconds, by utilizing AI technology. Pineapple launched its "My Stuff" per-item insurance in 2018 and expanded its offerings to include "My Ride" for auto insurance. The company has also formed a partnership with Travelers in the United States and provides a white-labeled version of its platform for that market.

TryCycle Data Systems Inc. is a Canadian technology company founded in 2016, focused on enhancing the treatment of individuals dealing with substance use, addiction, mental health issues, and post-traumatic stress disorders. The company has developed a predictive health technology system that monitors real-time behavior patterns and assesses risk factors associated with relapse. By enabling healthcare professionals to receive regular self-assessments from patients, TryCycle's system serves as an early warning tool that highlights unhealthy behaviors and triggers. This approach aims to bridge the gaps between various treatment providers, facilitating a more integrated support system for patients and allowing practitioners to address those at the highest risk effectively.

Azitra Inc. is a clinical-stage medical dermatology company based in Farmington, Connecticut, focused on developing microbiome-based therapeutics for skin diseases. Established in 2014, Azitra leverages its proprietary platform, which includes a microbial library of bacterial strains, to discover and create novel treatments for adverse skin conditions. The company's technology, developed in collaboration with researchers at Yale University and the Jackson Laboratory, is centered around a specific strain of the natural commensal bacteria Staphylococcus epidermidis. Additionally, Azitra employs artificial intelligence and machine learning to enhance the screening and prediction of therapeutic characteristics within its microbial library. By utilizing engineered proteins and live biotherapeutic products for topical application, Azitra aims to advance precision dermatology.

Paygilant Ltd. is a developer of mobile fraud prevention solutions, focusing on online transactions, payments, and money transfer fraud. Founded in 2014 and based in Ramat Gan, Israel, the company addresses the rising challenge of mobile fraud as the adoption of mobile payments increases. Paygilant offers a comprehensive suite of services, including account takeover prevention, new account fraud solutions, and transactional fraud protection. Its patented technology integrates six proprietary intelligence sets to ensure a frictionless user experience while maintaining security and user privacy. The company’s solutions provide end-to-end protection, from app download to ongoing transactions, effectively safeguarding legitimate customers against fraudulent activities in the evolving digital payment landscape.