Connecticut Innovations

Swanston Labs builds data-driven solutions aimed at disrupting the convergence of media, entertainment, technology, and commerce. The company focuses on leveraging innovative technologies to address the $7 trillion global leisure spending market. Swanston Labs operates under the Swanston Organization, which also includes Swanston Family Ventures and Swanston Philanthropy, collectively advancing the mission of innovation and inclusion.

Normunity is a biotechnology company that develops precision immuno‑oncology medicines, termed immune normalizers, designed to restore the body’s natural immune response against cancer. Leveraging a partnership with Dr. Lieping Chen’s laboratory at Yale School of Medicine, the company focuses on newly discovered mechanisms of immune disruption, such as the exclusion of T‑cells from immune‑sensitive tumors and other barriers to normal immune function. Its pipeline includes programs targeting these mechanisms to enable clinicians to treat cancer by reactivating the patient’s own immunity. Normunity operates from offices in Boston, Massachusetts, and West Haven, Connecticut.

VeraDermics is a dermatology company specializing in novel drug delivery mechanisms. It offers a dissolvable microneedle patch for treating skin conditions like warts, administering immunotherapy painlessly by stimulating the body's immune system.

Nimbus Power Systems designs and integrates zero-emission fuel cell systems for heavy-duty markets, develops fuel cell technology, and offers diesel-to-fuel-cell replacement solutions. Its architecture improves cell performance and eliminates the need for a DC/DC converter, enabling hydrogen fuel cells that emit no harmful pollutants.

CREW Carbon is a company dedicated to removing greenhouse gas emissions, particularly carbon dioxide, from wastewater through innovative technology. Utilizing engineered enhanced weathering, the company's approach harnesses the natural power of minerals to treat both municipal and industrial wastewater while permanently storing CO2. Operating within the environmental services sector, CREW Carbon focuses on greenhouse gas management and carbon removal, aiming to support businesses and governments in achieving their climate objectives. Through its climate tech solutions, the company strives to make a positive environmental impact.

GoodSam is a food and beverages company specializing in the production of snack and food products crafted from natural ingredients. The company operates a chocolate brand that focuses on manufacturing cocoa products sourced from regenerative farming practices. Its product offerings include a variety of items such as coffee, nuts, fruits, and seeds, as well as a range of chocolate products. This includes a sugar-free, vegan, and keto-friendly line that features chocolate bars, chocolate chips, and chocolate-coated nuts. These products incorporate allulose, a natural low-calorie sweetener derived from dates and figs, enabling GoodSam to provide healthier options that support small farmers.

AmpUp is a Silicon Valley-based company that specializes in electric vehicle charging solutions. It develops a reservable networking software that facilitates electric vehicle charging for drivers, hosts, and fleets. The company's platform establishes a peer-to-peer electric vehicle charging network, allowing businesses and property owners to manage multiple charging stations efficiently. By listing their chargers on AmpUp's network, users can earn revenue while contributing to electrification efforts. The software is designed to make the charging experience seamless and stress-free, catering to a diverse range of communities and enabling easy access to charging technology services.

Air Company is a carbon utilization firm focused on transforming carbon dioxide into consumer and industrial products. Utilizing its patented Carbon Conversion Reactor, the company mimics photosynthesis by combining air, water, and renewable energy to produce carbon-negative alcohols and fuels. Its product line includes AIR Vodka, AIR Hand Sanitizer, and AIR Eau de Parfum, showcasing its commitment to eco-friendly offerings. The company is advancing towards large-scale production of sustainable aviation fuel (SAF), which will be certified for sustainability by recognized organizations. With $40 million in venture capital funding and numerous prestigious awards, including TIME Best Inventions and the Keeling Curve Prize, Air Company aims to redefine the possibilities of carbon technologies and promote a regenerative future that harmonizes with nature.

Oxylus Energy develops innovative technology for converting CO2 into e-fuels. It aims to make carbon capture competitive, scalable, and circular, contributing to a decarbonized future.

Halda Therapeutics is a research-stage drug discovery company dedicated to developing next-generation precision medicine. The company employs a unique therapeutic modality that serves as a platform for addressing various disease states. By focusing on the discovery of novel therapies that modify disease-causing pathways, Halda Therapeutics aims to enable healthcare providers to offer more targeted treatments for their patients. Through its innovative approach, the company seeks to advance the field of precision medicine and improve patient outcomes.

Aware Recovery Care is a healthcare company specializing in in-home addiction treatment services for young adults struggling with drugs and alcohol. Their innovative, evidence-based model transforms the home into a treatment center, offering comprehensive care including withdrawal management, medication-assisted treatment, individual and family therapy, and integrated medical and behavioral health services. This approach enables patients to seek recovery while maximizing whole-person wellness and fostering collaborative care with individuals who have lived experience in addiction recovery.

Encapsulate is a biotechnology company focused on developing automated tumor-on-a-chip systems that facilitate personalized cancer treatment. The company's innovative technology allows for the growth of patients' cancer cells outside the body, creating micro tumors that can be preserved and utilized to assess the efficacy of various chemotherapy and biotherapeutic drugs. By screening the response profile of cancer patients to these treatments, Encapsulate aims to enable oncologists to tailor effective treatment regimens, improving outcomes in cancer care.

Founded in 2015 by Dr. Robert Schoelkopf, Quantum Circuits develops and manufactures quantum computers based on superconducting devices. The company focuses on creating full-stack quantum computers designed for efficient scaling, with a pioneering approach to error detection and correction.

Manifest Technologies advances AI-powered computational neuroimaging system that quantifies neural and symptom data.

Conduce Health is a healthcare technology company that offers a comprehensive solution for multi-specialty value-based care. It operates a platform designed to connect risk-bearing entities with specialists, addressing the challenges in specialty care management. The company focuses on providing downside protection for specialty care risks while streamlining the contracting process to facilitate participation in value-based care models. Additionally, Conduce Health aims to enhance patient volume and ensure that patients are matched with the most suitable specialists. Through its innovative approach, the company seeks to promote healthier lives by delivering personalized care and encouraging proactive well-being.

DeepLook Medical develops medical imaging software that uses shape-recognition to extract radiomic features from mammography images, revealing tissue morphology not visible to the unaided eye, and aims to improve early breast cancer detection, particularly in dense breast tissue, by identifying subtle data within radiological images and presenting features beyond human vision to help clinicians and reduce unnecessary procedures by lowering false positives.

Nest Collaborative provides a virtual lactation support platform offering breastfeeding guidance and care from board-certified lactation consultants for parents and expectant parents, year-round. The service emphasizes prevention, improved access to lactation care, and reduced costs by delivering evidence-based interventions that extend breastfeeding duration. Preventive lactation care addresses physiological, emotional, societal, and economic barriers through education, anticipatory guidance, reassurance, and skilled problem solving, alongside traditional problem-based support. The platform includes prenatal planning and ongoing lactation support from prenatal through postpartum, with online sign-up for consultations and clinician-supervised care at any stage.

Vita Health operates an online mental health care platform focused on providing high-quality treatment for adolescents and transitional age youth. The platform enables patients to receive quick and accessible care from licensed therapists through telehealth services. It addresses various mental health challenges, including anxiety, depression, and suicidal ideation, ensuring that young individuals can conveniently access the support they need from the comfort of their homes.

IntelliBoard, Inc. is a technology company based in Monroe, Connecticut, founded in 2015. It specializes in developing a learning analytics platform that serves educational institutions and corporate clients by providing insightful reporting and data analysis. The platform integrates with various Learning Management Systems to deliver real-time data on learner engagement, performance, and the effectiveness of educational content. By transforming raw data into accessible and visually appealing reports, including charts and graphs, IntelliBoard empowers educators and administrators to make informed decisions that enhance learning outcomes and operational efficiency. Its focus on both higher education and corporate training allows IntelliBoard to support clients in achieving their educational goals and optimizing their e-learning investments.

Cambium Carbon is an early-stage social enterprise focused on addressing climate change through innovative reforestation and urban wood reuse initiatives. The company collaborates with cities and various public and private partners to salvage fallen city trees that would otherwise end up in landfills. By transforming this wood waste into valuable resources, Cambium Carbon establishes reforestation hubs that create a circular economy for urban forests. These hubs not only generate revenue to support tree planting and maintenance projects but also foster sustainable job creation and contribute to the development of resilient urban environments. Through its efforts, Cambium Carbon aims to implement systems-level natural climate solutions that benefit both the environment and local communities.

Summer is a property management company that specializes in facilitating access to vacation homes through a unique rent-to-own program combined with short-term rentals. The company operates a homeownership platform designed to assist clients in purchasing second homes while also offering the opportunity to rent them out. By lowering entry and ongoing costs and minimizing the complexities associated with traditional real estate transactions, Summer enables users to easily find move-in-ready homes or select their ideal second home. Through its services, Summer aims to simplify the process of homeownership and enhance the vacation rental experience for clients.

Slooh is an online astronomy platform that connects robotic telescopes to the Internet, enabling live viewing, real-time celestial imaging, and educational exploration for the public and educators. Founded in 2003, Slooh operates flagship observatories and partners with institutions in locations such as Mt. Teide in the Canary Islands and in Chile, with live broadcasts from partner sites worldwide. Its automated observatories develop celestial images for Internet broadcast and support educational programs and media partnerships, making space exploration accessible to K-12 students, enthusiasts, and the general audience. The service collaborates with scientific institutions and engages in agreements to advance public access to space observations.

Anonybit develops decentralized technology to secure personal data and digital assets. It encrypts sensitive information like biometrics and private keys, distributing them across a peer-to-peer network for enhanced protection. The company uses proprietary multi-party computing and zero-knowledge proofs to facilitate matching functions in a decentralized manner.

Modifi Bio develops oncology therapeutics based on direct DNA modification. The company pursues a platform that modifies tumor DNA to render cancer cells irreparable while preserving healthy cells, aiming to disrupt conventional oncology drug development.

Raise Green is a fintech company dedicated to fostering a sustainable future. It enables everyday investors to participate in clean energy and climate solution projects, thereby democratizing renewable energy ownership, enhancing community resilience, and accelerating the transition to a decarbonized economy.

OOVA is a fertility diagnostic company that develops a personalized fertility assessment platform based on a paper-based urine test strip that measures hormones in daily samples. The system builds a longitudinal fertility profile using biochemistry and artificial intelligence to guide cycle management, menstrual health after pregnancy, and progression toward menopause. Originating as a spin-out from Mount Sinai Hospital in New York, OOVA aims to help users understand pregnancy prospects, identify reasons for conception challenges, and detect reproductive health issues such as PCOS. Its test kit measures luteinizing hormone and progesterone over a short window, with results delivered through a mobile application to support wellness guidance for users and input for healthcare providers. Founded in 2017 and based in New York, the company focuses on consumer-accessible diagnostics designed to empower women in conceiving and monitoring reproductive health.

Driver Technologies is a software company that provides a mobile application designed to document driving experiences while promoting safety. The app allows users to video record trips and to control their phone with voice commands, without requiring specialized hardware. It includes interior video recording and artificial intelligence-based features that alert drivers to risks, such as drifting out of lanes, approaching pedestrians, fatigue, or distraction. Additional capabilities include pedestrian collision warnings and turn-by-turn augmented reality navigation, along with video backup to capture on-road events. The solution aims to help drivers document trips, enhance situational awareness, and potentially support insurance considerations by providing recorded evidence of journeys.

2045 Studio operates as an exclusive professional networking platform, fostering connections among influential individuals of color. It partners with corporations to enhance employee diversity, inclusion, and advancement through its B2B services, which focus on cultivating inclusive leadership. Additionally, 2045 Studio offers a B2C service allowing users to join curated networks based on industry and shared experiences, promoting personal and professional growth.

Inbox Health Corp. is a digital healthcare company based in New Haven, Connecticut, founded in 2014. It specializes in developing a patient communication platform aimed at medical billers in the United States. The Inbox Health platform automates the patient communication process through bi-directional correspondence and utilizes proprietary algorithms, machine learning, and artificial intelligence. This enables patients to better understand their medical bills and access various payment options. By analyzing a wide range of data points across its customer base, the platform allows billers to personalize the billing, payment, and communication experiences for each patient, ultimately enhancing patient collections and overall satisfaction. The company's mission is to reduce administrative waste in healthcare by streamlining the billing and payment experience for patients.

RNAConnect specializes in developing enzymatic tools for visualizing and manipulating RNA, with a focus on low-abundance and long, structured RNAs. Their core product is a reverse transcriptase designed to provide greater visibility into these challenging RNA types and their various isoforms. This enzyme is optimized to synthesize cDNA with high fidelity and processivity, enabling researchers to study complex RNA template structures without the need for heat.

Bright Feeds is a food waste recycling company that addresses climate change and global food insecurity by transforming food waste into animal feed. Utilizing artificial intelligence and advanced drying technology, Bright Feeds diverts unwanted food from landfills and converts it into a nutrient-rich alternative to traditional feed sources like soy and corn. This innovative approach not only helps businesses meet their sustainability objectives but also enhances profit margins by turning food waste into high-quality nutritious feed for livestock. Through its services, Bright Feeds contributes to a more sustainable food system while tackling the challenges associated with food waste.

ReferWell is a healthcare technology company that offers a cloud-based platform designed to address the challenges associated with care transitions. By connecting healthcare providers into Virtually Integrated Networks, ReferWell enhances the patient journey through better visibility and management of all interactions. The platform facilitates streamlined referrals, point-of-care appointment scheduling, and supports care teams with tools like provider directory management and telehealth capabilities. This comprehensive suite of services enables healthcare providers and networks to improve patient compliance, reduce leakage, and close care gaps, ultimately leading to increased revenue and enhanced patient outcomes.

Bags is a loan discovery and management platform, built by and for the culture.

CINCH has created the first end-to-end real estate transaction ecosystem, providing agents and brokers everything they need to get deals done within a single application.

Peer Robotics develops collaborative mobile robots designed to bridge the gap between human and robotic work. Their adaptable robots learn from humans in real-time, providing efficient material handling solutions for small and medium-scale manufacturers.

Aceiss offers a compliance monitoring platform that enhances access security by providing real-time insights into user activity. It integrates with existing applications and security infrastructure to identify unusual behavior and protect privileged accounts, helping businesses anticipate potential security threats.

Modifi Bio develops oncology therapeutics based on direct DNA modification. The company pursues a platform that modifies tumor DNA to render cancer cells irreparable while preserving healthy cells, aiming to disrupt conventional oncology drug development.

Noteworthy AI equips fleet vehicles with smart cameras and AI technology to enhance the reliability and safety of electric distribution grids. Its autonomous system collects data during routine operations, enabling utilities to optimize asset management, reduce operational costs, and improve efficiency across various use cases.

FinTron is a fintech company that delivers investing and banking solutions for mobile-first users. Its consumer platform helps young post-college graduates begin investing through curated portfolios and educational modules that establish a foundation for long-term investing. The company also offers a B2B embedded wealth technology system that consolidates essential financial data and enables tracking of debt, savings, and investing accounts within a single platform, providing users with timely information and updates about their finances and investment activity. This combination positions FinTron to simplify personal finance management and support informed financial decisions for individuals and partner businesses alike.

Founded in 2013, Torigen Pharmaceuticals specializes in developing innovative cancer care solutions for pets. Based in Farmington, Connecticut, the company focuses on advancing scientific research to bring novel approaches to companion animal cancers.

PlazMod Technology specializes in developing and implementing innovative battery manufacturing processes. The company focuses on a groundbreaking materials processing technology designed to facilitate the production of structured materials systems. This technology aims to support industries worldwide in transitioning their energy systems towards greater electrification, contributing to a more sustainable global energy landscape.

Upswing Health is a digital orthopedic clinic that transforms the delivery of orthopedic care by combining artificial intelligence with medical expertise. The company focuses on managing low- and medium-acuity orthopedic conditions, such as injuries to the ankle, knee, elbow, and shoulder, as well as sprains and fractures. Through its community-powered platform, Upswing Health enables athletes to accurately identify injuries and guides them on their recovery journey. The innovative care delivery model not only enhances patient outcomes but also reduces healthcare costs, ensuring that athletes have convenient access to quality information and support from both athletic trainers and orthopedic specialists.

Encapsulate is a biotechnology company focused on developing automated tumor-on-a-chip systems that facilitate personalized cancer treatment. The company's innovative technology allows for the growth of patients' cancer cells outside the body, creating micro tumors that can be preserved and utilized to assess the efficacy of various chemotherapy and biotherapeutic drugs. By screening the response profile of cancer patients to these treatments, Encapsulate aims to enable oncologists to tailor effective treatment regimens, improving outcomes in cancer care.

CoreChain Technologies specializes in B2B payments using blockchain technology. Its platform securely automates the exchange of transaction data and funds, reducing reconciliation errors and unlocking tied-up working capital.

Source Defense Ltd. is a cybersecurity company specializing in website security software that prevents attacks originating from third-party sources. Founded in 2014 and headquartered in Rosh-ha’ayin, Israel, with additional offices in Beer-Sheva and Stamford, Connecticut, the company offers a cloud-based Software-as-a-Service platform. This platform enables site owners to effectively manage their security by setting and enforcing permissions, receiving real-time alerts, and monitoring the activities of third-party vendors on their sites. Source Defense aims to eliminate the security risks associated with third-party integrations, allowing businesses to save significant time and resources while maintaining high performance and safety for site visitors. Its tailored solutions include VICE products designed for various sectors, including financial institutions, insurance companies, e-commerce, and publishing.

Covr Financial Technologies, Inc. is a digitally enabled brokerage general agency based in Boise, Idaho, founded in 2013. The company specializes in providing life, long-term care, and disability insurance solutions tailored for financial institutions, advisors, and their clients. Covr offers a suite of digital platforms, including Covr Advisor, which helps financial advisors meet their clients' insurance needs by selecting appropriate products; Covr Consumer, which allows banks and credit unions to sell life insurance directly to customers; and Covr Insights, a tool for managing and analyzing existing life insurance policies. The company serves over 24,000 financial advisors and 13 million customers across 30 financial institutions, facilitating a simplified and efficient sales process for life insurance products.

1906 is a cannabis company founded in 2016, dedicated to producing fast-acting, functional products designed to enhance wellness. Named after the year when cannabis was last widely recognized as a medicinal option, the company aims to reintegrate the plant into modern health practices rather than limiting its use to recreational purposes. Unlike many cannabis brands that prioritize high THC content, 1906 focuses on health-conscious consumers who seek precise and predictable effects. Its innovative fast-acting technology allows products to take effect within 20 minutes, contrasting with typical edibles that may require up to two hours. By offering a range of products targeting specific wellness needs—such as sleep, focus, relaxation, energy, and intimacy—1906 caters to professionals, busy parents, athletes, and health enthusiasts. The company has established itself as a leader in the functional cannabis market and expanded accessibility through a direct-to-consumer platform launched in 2023. With strong growth driven by demand for wellness-oriented cannabis, 1906 is well-positioned for continued success as legalization and consumption trends evolve across the United States.

Nest Collaborative provides a virtual lactation support platform offering breastfeeding guidance and care from board-certified lactation consultants for parents and expectant parents, year-round. The service emphasizes prevention, improved access to lactation care, and reduced costs by delivering evidence-based interventions that extend breastfeeding duration. Preventive lactation care addresses physiological, emotional, societal, and economic barriers through education, anticipatory guidance, reassurance, and skilled problem solving, alongside traditional problem-based support. The platform includes prenatal planning and ongoing lactation support from prenatal through postpartum, with online sign-up for consultations and clinician-supervised care at any stage.

Founded in Stamford, Connecticut in 2019, NourishedRx specializes in personalized nutrition solutions for health plan members with diet-sensitive chronic conditions or at risk of nutrition insecurity. They provide tailored meal plans and education to improve clinical outcomes and reduce healthcare costs.

Wellinks specializes in wearable health technologies designed to enhance clinical outcomes. Founded in 2014, the company is renowned for its innovative smart strap that monitors scoliosis brace wear duration and tightness, empowering patients, parents, and doctors with real-time data for informed treatment decisions.

VeraDermics is a dermatology company specializing in novel drug delivery mechanisms. It offers a dissolvable microneedle patch for treating skin conditions like warts, administering immunotherapy painlessly by stimulating the body's immune system.

FuturesTHRIVE develops an AI platform to identify and track pediatric mental health, using artificial intelligence, sentiment analysis and machine learning to establish a mental health baseline that helps doctors and families understand a child's mental health and identify potential conditions early. The company also offers a digital mental health screener for children aged five to nine, collecting data on experiences, relationships and other factors to support informed decisions about a child's well-being.

Lessonbee Inc. is an educational technology company that specializes in providing an online learning platform and digital curriculum focused on health and wellness for students in grades K-12. Founded in 2017 and based in Mount Vernon, New York, Lessonbee offers a cloud-based reflective learning system that includes adaptive lessons and a shared content library. This platform enables teachers to access up-to-date, culturally responsive, and medically accurate health education content, track student assignments, and foster student engagement through regular reflection. Additionally, Lessonbee incorporates its proprietary HealthIQ analytics to evaluate student health goals and school climate, recommending personalized content from its extensive library of self-paced classes and video-based lessons aligned with state and national health education standards. By promoting collaboration among educators, parents, and healthcare providers, Lessonbee aims to enhance student well-being and health literacy.

Owl's Brew, founded in 2013 by tea sommelier Jennie Ripps and Maria Littlefield, specializes in all-natural tea products crafted in New York City. The company offers two main product lines: Owl's Brew Mixer, which features tea-based craft cocktail mixers, and Owl's Brew Boozy Tea. Their beverages are made from whole tea leaves, fruits, spices, and herbs, ensuring that no added or artificial flavors are included. This commitment to quality allows consumers to enjoy a diverse range of flavored tea products that emphasize freshness and natural ingredients.

DiA Imaging Analysis Ltd. is a technology company based in Beersheba, Israel, specializing in AI-powered ultrasound analysis designed to enhance the evaluation of cardiac function and other medical conditions. Founded in 2009, DiA offers a range of innovative applications, including LVivo EF for automated ejection fraction evaluation, LVivo RV for right ventricle analysis, and LVivo Strain, which assesses myocardial strain as an early indicator of reduced left ventricular function. Their tools simplify the ultrasound imaging process by providing automated analysis and optimal view selection, improving the diagnostic capabilities of clinicians. DiA's technology is compatible with various ultrasound devices and healthcare IT systems, streamlining the detection of clinical abnormalities. The company holds FDA and CE clearances and serves thousands of users globally, addressing critical challenges in ultrasound utilization by enabling more accurate and efficient image analysis through advanced pattern recognition and machine learning algorithms.

Shelf is a knowledge management platform aimed at improving the efficiency of distributed teams by streamlining the process of finding and managing organizational knowledge. The platform addresses the challenges of content disorganization prevalent in remote work environments, where teams may face difficulties in accessing critical information. By leveraging natural language processing, Shelf enhances search capabilities, enabling users to quickly locate the answers they need. The platform integrates knowledge management best practices developed in collaboration with experts, ensuring that users can manage content effectively while reducing the time spent on knowledge retrieval and maintenance. Shelf's mission is to empower teams globally to learn, share, and succeed without the burdens of excessive work or inefficient tools, ultimately reimagining the library concept for the modern workplace.

CoreChain Technologies specializes in B2B payments using blockchain technology. Its platform securely automates the exchange of transaction data and funds, reducing reconciliation errors and unlocking tied-up working capital.

BEKhealth is a clinical research software company that utilizes an AI-powered platform to enhance the efficiency of clinical trials and observational studies. By automating various processes, BEKhealth enables organizations to better understand their patient populations, optimize feasibility, and speed up site selection. The platform extracts and processes both structured and unstructured data from electronic medical records, allowing for a more comprehensive understanding of trial eligibility criteria. This capability leads to the identification of significantly more protocol-eligible candidates, resulting in a tenfold increase in qualified patients and halving the enrollment timeline. Through its innovative approach, BEKhealth aims to reduce costs and streamline the overall clinical research process for its clients.

Triax Technologies specializes in a connected Internet of Things (IoT) worksite platform tailored for construction, energy, and heavy industrial sectors. The company aims to enhance safety and efficiency in complex work environments by utilizing innovative technology and real-time data analytics. Its key offering, the Spot-r system, improves worksite visibility and risk management by linking workers, equipment, and operations through a scalable infrastructure that includes wearable devices, sensors, and a cloud-based dashboard. This system provides real-time insights into site access, personnel and equipment locations, safety incidents, and emergency protocols, enabling firms to streamline operations and enhance safety measures. In response to the COVID-19 pandemic, Triax launched Proximity Trace, which offers alerts for social distancing and contact tracing to help protect essential workers and facilitate a safe return to work. Overall, Triax Technologies is committed to transforming challenging work environments through intelligent, data-driven solutions.

Lumeda Inc. is a biotechnology company based in Rocky Hill, Connecticut, founded in 2020. It specializes in developing advanced photonic tools that facilitate intraoperative photodynamic therapy (PDT) for lung cancer treatment. Lumeda's innovative solutions include light delivery instrumentation and proprietary software designed to automate the PDT light delivery process, targeting tumor sites with precision and enhancing treatment efficacy. The company's technology aims to improve the planning and delivery of PDT, offering a more streamlined and effective approach during non-small cell lung cancer surgeries. By integrating advanced photonics and AI-driven software, Lumeda enhances the consistency and reliability of PDT, ultimately aiming to reduce post-operative recurrence and improve patient outcomes. The company collaborates closely with leading medical institutions to advance its solutions in clinical settings.

Inbox Health Corp. is a digital healthcare company based in New Haven, Connecticut, founded in 2014. It specializes in developing a patient communication platform aimed at medical billers in the United States. The Inbox Health platform automates the patient communication process through bi-directional correspondence and utilizes proprietary algorithms, machine learning, and artificial intelligence. This enables patients to better understand their medical bills and access various payment options. By analyzing a wide range of data points across its customer base, the platform allows billers to personalize the billing, payment, and communication experiences for each patient, ultimately enhancing patient collections and overall satisfaction. The company's mission is to reduce administrative waste in healthcare by streamlining the billing and payment experience for patients.

Enko Chem, Inc., established in 2017 and based in Woburn, Massachusetts, specializes in the discovery and development of small-molecule and novel products designed to protect crops from pests and diseases. The company's proprietary technology platform enables it to swiftly identify safe and cost-effective solutions, contributing to sustainable food production.

Artizan Biosciences, Inc. is a biotechnology company focused on developing small molecule drugs for human use, particularly targeting diseases linked to intestinal inflammation. Founded in 2016 and headquartered in New Haven, Connecticut, the company employs its proprietary IgA-SEQ technology platform to identify and characterize disease-driving bacteria within the intestinal microbiota. This innovative approach aims to create precision therapeutics that address the root causes of various serious conditions, including digestive disorders, obesity, autoimmune diseases, and a range of other health issues affecting the skin, lungs, and central nervous system. By focusing on unmet medical needs, Artizan Biosciences seeks to provide novel treatment options for patients.

Leal Health is a patient-centric platform that employs AI to connect cancer patients with suitable clinical trials. It aims to enhance cancer care by facilitating trial search, matching, and enrollment for patients and their healthcare providers.

Athena Therapeutics, LLC is a biopharmaceutical company based in New Haven, Connecticut, that specializes in developing innovative drugs targeting defects in NAD metabolism related to cancer. Incorporated in 2018, the company employs advanced methodologies to identify and characterize altered states of NAD metabolism, enabling selective targeting of tumor cells while sparing normal tissues. To enhance its research capabilities, Athena has assembled a team of experts in NAD metabolism, including Dr. Emmanuel Burgos, who leads the internal discovery biology efforts. Additionally, the company has established a Scientific Advisory Board comprising prominent figures in the field, such as Professor Vern Schramm and Dr. Leonard Post, who bring extensive knowledge in enzymology and oncology drug development, respectively. This strategic focus positions Athena Therapeutics to advance its drug development pipeline effectively.

Diameter Health, Inc. is a technology company that specializes in developing software solutions for healthcare organizations. Founded in 2013 and headquartered in Farmington, Connecticut, with an additional office in Wellesley, Massachusetts, the company focuses on enhancing the quality and interoperability of patient information. Its flagship product, Fusion, facilitates intelligent data exchange by normalizing and cleansing data from certified Electronic Health Records (EHRs), making it suitable for clinical use and analytics. Diameter Health also offers various other solutions, including Data Dashboard, which provides data quality ratings and dashboards for clinical documentation, and a Payer Edition for generating standardized supplemental reporting data. Additionally, the company provides tools for automatic data updates and scalable hosting solutions. Diameter Health serves a diverse clientele that includes government entities, health information exchanges, payers, healthcare IT vendors, life insurers, and health systems.

Alphina Therapeutics is a biotechnology company specializing in the development of targeted cancer therapies. It focuses on leveraging proprietary biomarkers and insights to identify and treat cancer patients with NAD Metabolic Deficiencies (NMD). The company aims to develop companion diagnostics and translate these findings into clinical applications.

WRM Software specializes in developing business productivity applications aimed at enhancing operational efficiency. Their key offerings include Storm Manager and Ops Manager, which are designed for ease of use and facilitate seamless integration between field and office operations. These applications ensure that all team members have access to the most current information at all times. WRM Software supports emergency response operations and field service management, providing businesses with essential tools to manage their resources effectively.

Azitra is a clinical-stage dermatology company that leverages skin microbiome knowledge to develop novel treatments for adverse skin conditions and diseases.

Point Pickup Technologies is a mobile app delivery platform that addresses on-demand, pre-scheduled, and recurring same-day delivery needs across various sectors. It offers a comprehensive solution for middle and last-mile deliveries, catering to a wide range of industries including big-box retail, grocery, liquor, and pharmaceuticals. The platform utilizes precise matching technology to connect delivery requests with suitable drivers, which can include everyday individuals with personal vehicles as well as professional commercial drivers. This enables businesses to efficiently deliver goods to their final destinations while providing real-time tracking of packages. Operating across all major markets in the United States, Point Pickup also prioritizes underserved secondary markets, enhancing accessibility for various businesses and consumers.

Biorez is a medical device company that develops bioresorbable scaffold implants to regenerate functional musculoskeletal tissue in vivo. Its products include off-the-shelf implants for anterior cruciate ligament reconstruction that spare donor tissue, and PLLA-based devices for soft-tissue regeneration in the knee, such as the L-C Ligament; the company also markets GRAFT, an FDA 510(k)-cleared device for soft-tissue augmentation of the rotator cuff, along with related implants to support repairs during healing. Biorez uses poly-L-lactic acid polymers to stabilize surgical repairs while the body regenerates tissue, enabling rehabilitation. The company was founded in 2008 and is headquartered in New Haven, Connecticut.

IvyTech Design was founded with a mission to develop adjustable-angle orthopedic instruments that can distract, align, and compress bones more precisely than current tools. Our patented and patent-pending technology addresses key challenges in foot and spine procedures, which suffer from high complication rates (up to 20-25%), costly revision surgeries, and suboptimal patient outcomes. IvyTech Design’s instruments will enable surgeons to precisely angle bones, providing superior alignment and access in foot and spine operations. Surgeons, hospitals, and patients will all benefit from this technology, as we aim to lower complication and revision rates, reduce surgical times, and improve patient outcomes.

Shelf is a knowledge management platform aimed at improving the efficiency of distributed teams by streamlining the process of finding and managing organizational knowledge. The platform addresses the challenges of content disorganization prevalent in remote work environments, where teams may face difficulties in accessing critical information. By leveraging natural language processing, Shelf enhances search capabilities, enabling users to quickly locate the answers they need. The platform integrates knowledge management best practices developed in collaboration with experts, ensuring that users can manage content effectively while reducing the time spent on knowledge retrieval and maintenance. Shelf's mission is to empower teams globally to learn, share, and succeed without the burdens of excessive work or inefficient tools, ultimately reimagining the library concept for the modern workplace.

Encapsulate is a biotechnology company focused on developing automated tumor-on-a-chip systems that facilitate personalized cancer treatment. The company's innovative technology allows for the growth of patients' cancer cells outside the body, creating micro tumors that can be preserved and utilized to assess the efficacy of various chemotherapy and biotherapeutic drugs. By screening the response profile of cancer patients to these treatments, Encapsulate aims to enable oncologists to tailor effective treatment regimens, improving outcomes in cancer care.

EyeControl is a medical technology company specializing in innovative communication solutions for healthcare. It develops devices that enable patients, particularly those with limited mobility or speech impairments, to communicate using eye movements. The company's flagship product is an intensive care unit communication device featuring an infrared camera and a connected computer that translates blinks and eye movements into commands.

Founded in 2012, Voiceitt develops mobile applications that use automatic speech recognition technology to enable individuals with speech impairments or motor disabilities to communicate effectively. Its AI-driven engine translates distorted pronunciation into intelligible speech, enhancing independence and quality of life for users.

GeneDx specializes in delivering personalized insights from genomic data to improve health outcomes. It combines extensive genetic expertise with advanced data science capabilities.

Enrich Therapeutics Inc. is a biotechnology company based in Worcester, Massachusetts, that specializes in developing innovative single-cell isolation technology for life science research. The company offers LASUM, a technology that enables the selection and isolation of single cells using a microscope, applicable to a variety of cell types including suspension, adherent, and challenging tissue samples. Enrich Therapeutics' solutions enhance scalability and affordability across several applications such as antibody drug discovery, next-generation sequencing (NGS), and the development of adoptive cell therapies. In addition to its core technology, the company provides services in phage display library engineering, affinity-on-demand binder selection, CAR-T cell line development, B-cell isolation, and precision cell isolation for NGS analysis. Founded in 2018, Enrich Therapeutics aims to advance life science research through its cutting-edge tools and methodologies.

Simcha Therapeutics is a biopharmaceutical company focused on developing engineered cytokine immunotherapy for cancer treatment. Founded in 2018 and headquartered in New Haven, Connecticut, the company utilizes directed evolution to create novel cytokines that enhance the immune system's ability to combat diseases. Its lead program, ST-067, is a designer IL-18 cytokine that has demonstrated significant antitumor effects in animal models, both as a standalone treatment and in combination with anti-PD-1 checkpoint inhibitors. This innovative approach aims to provide patients with more effective immunotherapies, thereby improving their ability to fight cancer.

Invixium Inc., founded in 2012 and based in Markham, Canada, is a global provider of biometric solutions designed to enhance safety, health, security, and productivity for enterprises. The company offers a range of products including Ixm Mycro for personalized home environments, Ixm Touch for employee time tracking, IXM Titan for face recognition and edge computing, IXM Merge for indoor fingerprint tracking, and Ixm Sense for industrial installations. Invixium's solutions also include touchless biometric technologies with face recognition and temperature detection for access control, workforce management, and visitor screening. The company's products are deployed across various industries such as government, banking, healthcare, and education in over 60 countries.

1touch.io offers a network-based solution that continuously analyzes traffic and repository stores connected to your network. It detects and tracks all elements storing, processing, or sharing personal data, whether structured or unstructured, in motion or at rest, and even unknown data.

Covr Financial Technologies, Inc. is a digitally enabled brokerage general agency based in Boise, Idaho, founded in 2013. The company specializes in providing life, long-term care, and disability insurance solutions tailored for financial institutions, advisors, and their clients. Covr offers a suite of digital platforms, including Covr Advisor, which helps financial advisors meet their clients' insurance needs by selecting appropriate products; Covr Consumer, which allows banks and credit unions to sell life insurance directly to customers; and Covr Insights, a tool for managing and analyzing existing life insurance policies. The company serves over 24,000 financial advisors and 13 million customers across 30 financial institutions, facilitating a simplified and efficient sales process for life insurance products.

IntelliBoard, Inc. is a technology company based in Monroe, Connecticut, founded in 2015. It specializes in developing a learning analytics platform that serves educational institutions and corporate clients by providing insightful reporting and data analysis. The platform integrates with various Learning Management Systems to deliver real-time data on learner engagement, performance, and the effectiveness of educational content. By transforming raw data into accessible and visually appealing reports, including charts and graphs, IntelliBoard empowers educators and administrators to make informed decisions that enhance learning outcomes and operational efficiency. Its focus on both higher education and corporate training allows IntelliBoard to support clients in achieving their educational goals and optimizing their e-learning investments.

CytoVeris develops optical-based technologies that assist surgical oncologists in identifying and removing tumor tissue during cancer resection surgery. Its devices enhance surgeons' ability to achieve clean margins, while its OncoMap system detects molecular signatures unique to cancer cells. Founded by Alan Kersey in Farmington, Connecticut in 2018.

MindNest Health, Inc. is a New Haven, Connecticut-based company that develops a digital platform designed to provide parents with access to clinically validated behavioral interventions for their children. Founded in 2016, MindNest Health focuses on addressing various developmental challenges, offering programs specifically for ADHD, autism, and disruptive behaviors, as well as training modules aimed at anxiety and substance abuse. The platform aims to support parents during critical times when they seek assistance for their children's mental health, thereby reducing barriers to care and alleviating parental stress. By providing evidence-based solutions, MindNest Health envisions fostering an environment where children can reach their full potential and families can thrive.

WAVE was created with a mission to end drowning, a leading cause of death in children and adults. Our product works with lifeguards and parents to detect drowning at the first sign of danger.

ReferWell is a healthcare technology company that offers a cloud-based platform designed to address the challenges associated with care transitions. By connecting healthcare providers into Virtually Integrated Networks, ReferWell enhances the patient journey through better visibility and management of all interactions. The platform facilitates streamlined referrals, point-of-care appointment scheduling, and supports care teams with tools like provider directory management and telehealth capabilities. This comprehensive suite of services enables healthcare providers and networks to improve patient compliance, reduce leakage, and close care gaps, ultimately leading to increased revenue and enhanced patient outcomes.

Founded in 2018 by scientists from Yale University's Strittmatter Lab, ProteoWise specializes in developing innovative proteomic technology. Its flagship product is a 3D nanoscale protein capturing material that simplifies western blot analysis while providing high information content and throughput at a low cost.

Inbox Health Corp. is a digital healthcare company based in New Haven, Connecticut, founded in 2014. It specializes in developing a patient communication platform aimed at medical billers in the United States. The Inbox Health platform automates the patient communication process through bi-directional correspondence and utilizes proprietary algorithms, machine learning, and artificial intelligence. This enables patients to better understand their medical bills and access various payment options. By analyzing a wide range of data points across its customer base, the platform allows billers to personalize the billing, payment, and communication experiences for each patient, ultimately enhancing patient collections and overall satisfaction. The company's mission is to reduce administrative waste in healthcare by streamlining the billing and payment experience for patients.

Aero Therapeutics is a medical device company focused on improving the treatment of respiratory issues, particularly in low-resource settings. The company has developed an innovative device specifically designed to address neonatal respiratory problems. This device oxygenates, warms, humidifies, and sterilizes air before delivery, all within a mobile enclosure. By providing affordable and effective solutions, Aero Therapeutics aims to empower clinicians to better care for infants facing respiratory challenges in underserved environments.

Lessonbee Inc. is an educational technology company that specializes in providing an online learning platform and digital curriculum focused on health and wellness for students in grades K-12. Founded in 2017 and based in Mount Vernon, New York, Lessonbee offers a cloud-based reflective learning system that includes adaptive lessons and a shared content library. This platform enables teachers to access up-to-date, culturally responsive, and medically accurate health education content, track student assignments, and foster student engagement through regular reflection. Additionally, Lessonbee incorporates its proprietary HealthIQ analytics to evaluate student health goals and school climate, recommending personalized content from its extensive library of self-paced classes and video-based lessons aligned with state and national health education standards. By promoting collaboration among educators, parents, and healthcare providers, Lessonbee aims to enhance student well-being and health literacy.

Founded in 2009 by Yale scientists and a chemical industry veteran, P2 Science is a venture-backed company specializing in renewable specialty chemicals. It converts renewable feedstocks like vegetable oils into high-value products such as flavor, fragrance, and cosmetics ingredients, serving diverse markets including food, personal care, and industrial cleaning.

Enviro Power, LLC is a Connecticut-based company that specializes in developing and marketing innovative heating equipment for both residential and commercial applications. Founded in 2013, the company features its flagship SmartWatt Boiler technology platform, which is designed to generate electricity at near-zero costs while meeting heating demands. This advanced system transforms conventional heating infrastructure into a dual-purpose energy platform, enabling building owners to benefit from reduced utility bills and enhanced grid resiliency. By providing backup power and supporting grid stability, Enviro Power aims to lower carbon footprints and improve energy efficiency for millions of users.

IsoPlexis is a life science technology company based in Branford, Connecticut, established in 2013. It specializes in developing a single-cell detection system that identifies a wide array of patient immune responses at the single-cell level. The company's platform focuses on cell-based proteomic systems and biomarkers, allowing for the assessment of therapeutic safety and efficacy, monitoring of disease progression, and exploration of functional protein biology and cellular signaling networks. IsoPlexis's technology enables clients to predict cancer patient responses to various novel immunotherapies and cellular therapies, thereby enhancing therapeutic development and informing clinical decision-making.

Better Rhodes is a premium beverage platform and retailer focused on alcohol-free drinks, including non-alcoholic wines, beers, and spirits. The company provides services from product development, wholesale and go-to-market support to doorstep delivery of curated non-alcoholic beverages and subscription boxes designed to align with wellness goals and lifestyle preferences.

BioWave Corporation is a manufacturer of innovative pain management devices that utilize patented technology to block pain signals at their source. The company's product line includes BioWavePENS, a percutaneous electrical nerve stimulation device for severe chronic, acute, and postoperative pain; BioWavePRO, a comprehensive pain therapy system for various pain types; BioWaveHOME, designed for at-home pain relief; and BioWaveGO, an over-the-counter solution for pain management. These devices deliver therapeutic electrical signals through the skin to the underlying tissues, effectively interrupting the transmission of pain signals to the brain, similar to the effect of a chemical anesthetic. BioWave's offerings also consist of accessories and disposable electrodes, serving a diverse clientele that includes professional athletes, U.S. veterans, active military personnel, and pain management specialists. Founded in 1997 and headquartered in Norwalk, Connecticut, BioWave is committed to providing effective neuromodulation therapy for patients seeking relief from various pain conditions.

Pineapple Tech Pty Ltd is a South African company that operates a peer-to-peer insurance platform, providing short-term insurance coverage to its members. Founded in 2017 and based in Johannesburg, the company allows users to pay and track their premiums online while selecting their preferred network for pooling. Pineapple aims to innovate the insurance experience by aligning incentives with users, offering transparency about premium usage, and returning any unused premiums to members. The platform simplifies the insurance process, enabling users to obtain coverage quickly, often in under 60 seconds, by utilizing AI technology. Pineapple launched its "My Stuff" per-item insurance in 2018 and expanded its offerings to include "My Ride" for auto insurance. The company has also formed a partnership with Travelers in the United States and provides a white-labeled version of its platform for that market.

Founded in 2016, TryCycle Data Systems develops predictive health technology that learns human behavior patterns in real-time to estimate relapse risks for individuals undergoing treatment for substance use disorders, mental health conditions, and post-traumatic stress disorders. Its system enables healthcare professionals to detect unhealthy behaviors, identify at-risk patients, and intervene early.

Azitra is a clinical-stage dermatology company that leverages skin microbiome knowledge to develop novel treatments for adverse skin conditions and diseases.

Founded in 2014, Paygilant specializes in mobile fraud prevention solutions for online transactions and payments. Its offerings include account takeover protection, new account fraud detection, and transactional fraud solutions. The company's platform provides frictionless authentication, safeguarding the entire user journey from app download to ongoing transactions while ensuring a smooth payment experience.