Connecticut Innovations is the state's venture capital arm, based in New Haven, that finances and supports innovative, growing companies across technology-driven sectors in Connecticut. It provides flexible capital, strategic guidance, and access to a broad network of partners and talent to help portfolio companies scale. The organization invests across stages, from seed to later rounds, and operates sector-focused funds in areas such as artificial intelligence and quantum technologies, climate tech, and bioscience, aiming to strengthen Connecticut's innovation ecosystem and sustain entrepreneurship in the region.

Elm Street Ventures is a New Haven, Connecticut based venture capital firm that concentrates on seed and early-stage investments in life sciences and technology. It targets opportunities built on intellectual property developed at Yale University and other regional research institutions, spanning New York City through Southern New England. The firm supports scientists and entrepreneurs by providing initial capital and access to experienced management, which may serve as interim CEOs or operating chairs, and it sometimes co-founds companies with founders. Typical investments range from several hundred thousand dollars to over a million, with follow-on funding and occasional syndication with other investors. Focus areas include therapeutics, medical devices, diagnostics, laboratory tools and services, software, and sustainable technologies. Elm Street Ventures emphasizes markets with solid patent protection, defensible positions, and strong management teams within the Yale-New Haven ecosystem.

Safer Made is a venture capital firm based in North Branford, Connecticut, founded in 2017. The company invests in and supports startups and scale-ups that develop safer and more sustainable chemistries and materials, with a focus on removing or reducing harmful chemicals from products and manufacturing processes. It collaborates with leading brands and retailers to accelerate adoption of safer solutions, leveraging expertise in chemistry, function, and applications to identify opportunities and help portfolio companies achieve safety and sustainability claims. The firm aims to enable healthier products and cleaner environments by backing innovations that address consumer demand for safer products.

Fairview Capital Partners is an independent investment management firm focused on private markets. Founded in 1994 and headquartered in West Hartford, Connecticut, with an office in San Francisco, it builds portfolios across venture capital, diverse and emerging managers, and direct co-investments, and provides funds-of-funds investment management. The firm serves institutional clients including foundations, endowments, pension plans, and family offices. It is known for an entrepreneurial spirit, a diverse leadership team, and an inclusive investment approach, with a substantial minority-owned status among U.S. investment firms. The company offers investment management services to a family of venture capital and private equity funds-of-funds.

Canaan Partners is a global early-stage venture capital firm founded in 1987 and headquartered in San Francisco. It focuses on supporting technology and healthcare startups at the seed and early stages, investing across sectors such as fintech, enterprise software and cloud, marketplaces, frontier technologies, biopharma, digital health and medtech. The firm maintains an international footprint with offices in Israel and India and backs entrepreneurs by leveraging a broad network of strategic partners, customers and follow-on investors to help transform innovative ideas into global companies.

LaunchCapital is a venture capital firm founded in 2008 that provides seed and early-stage funding to technology-driven companies. It targets sectors including commerce, marketplace platforms, consumer products, media and entertainment, enterprise software and services, emerging technologies, data, finance, healthcare and medical technology. The firm combines capital with a hands-on approach, offering access to a network of entrepreneurs, advisory services and accelerators to support growth and prepare companies for subsequent venture funding. It emphasizes capital efficiency and long-term value creation, often collaborating with founders over multiple growth cycles, and maintains offices in Boston, New York, New Haven and San Francisco.

Axiom Venture Partners is a venture capital firm based in East Hartford, Connecticut, that provides funding to technology and biotechnology companies across the United States. It engages with startups and growth companies at various stages, with a focus on mid- to late-stage opportunities, and concentrates on sectors such as communications, software, internet infrastructure, information technology, and related high-technology fields.

Since its founding in 2008, Cava Capital has been a venture capital firm based in Connecticut that actively supports entrepreneurs through development and growth stages. It focuses on consumer health and wellness, mobile, marketing technology, software as a service, marketplaces, and active lifestyle sectors, and pursues opportunities in digital marketing. The firm often leads or participates significantly in investments and emphasizes adding value beyond capital, including sales, marketing, and business development. Through its Cava Studio portfolio development strategy, it partners with founders in a hands-on capacity, acting as a founder and operator to de-risk and accelerate growth. Cava Capital has built a track record of helping startups achieve growth and exits and is described as a development-focused investor with an emphasis on revenue drivers and long-term returns.

Regeneron Ventures is the corporate venture capital arm of Regeneron Pharmaceuticals, based in Greenwich, Connecticut. It invests in early-stage and emerging biotechnology companies, focusing on novel therapeutic platforms, drug discovery technologies, and breakthrough biomedical innovations across areas such as oncology, immunology, genetics, and precision medicine. The firm supports seed and growth-stage investments and often collaborates with other investors and industry partners to accelerate scientific progress, aiming to translate research into therapies and health technologies that align with Regeneron's biotechnology ecosystem.

Stamford, Connecticut-based venture and growth equity firm focused on healthcare information services and financial services technology. Founded in 2014, Oak HC/FT backs companies in the United States and Europe, aiming to transform healthcare and fintech through strategic counsel, board-level involvement, and access to a broad industry network. The firm invests in growth and early-stage opportunities, typically deploying tens of millions of dollars per deal, and supports portfolio companies across their lifecycle. Oak HC/FT is affiliated with Oak Investment Partners’ healthcare and fintech teams, reflecting a sector-focused approach. The firm has a track record of notable exits, including IPOs and multiple portfolio companies valued at over $1 billion.

Werth Ventures, based in Woodbridge, Connecticut, is a family office established in 2009 that makes investments across the healthcare sector, from seed to late-stage opportunities. The firm focuses on pharmaceuticals, biotechnology, medical devices, equipment, distribution, facilities, and managed health care, and participates in angel investing to support startup companies in pharmaceutical, veterinary, and medical device fields. Its activity includes funding projects aiming to develop cancer treatments, cardiovascular therapies, pain management, and innovative diagnostics and imaging technologies, as well as autoinjector devices and point-of-care tests. Werth Ventures seeks to back early and growth-stage ventures with potential to advance medical science and patient care.

Hillside Ventures is a student-run venture fund affiliated with the University of Connecticut, based in Mansfield, Connecticut. Founded in 2020, the organization provides hands-on, early-stage investing experience for students under mentorship from alumni, supporting entrepreneurship at UConn. The fund targets companies in sustainability, insur-tech, and ed-tech, offering students real-world venture capital exposure as they evaluate and invest in startups linked to the university community. Through this program, participants gain practical experience in deal sourcing, analysis, and mentoring while contributing to the growth of entrepreneurship within the campus ecosystem. Hillside Ventures seeks to cultivate diverse perspectives and prepare participants for careers in private capital and venture investing, aligning student involvement with regional innovation and industry collaboration.

OrbiMed is a global healthcare-focused investment firm founded in 1989 and headquartered in New York. It manages assets across public and private markets and pursues opportunities across the healthcare spectrum, including biopharmaceuticals, medical devices, diagnostics, digital health, and health services. The firm invests in startups, growth-stage companies, and established entities, leveraging scientific and medical expertise to support development and commercialization. It also offers financing solutions such as structured debt and royalty monetization for intellectual property and medical diagnostics.

Bulldog Innovation Group is a venture capital firm based in New Haven, Connecticut, focused on funding startups founded by Yale alumni. The firm supports seed-stage ventures with mentorship, capital, and expertise to help Yale entrepreneurs grow, leveraging its network to create opportunities for entrepreneurs and investors and to build a Yale-centric ecosystem. It concentrates on sectors such as healthcare devices and supplies, software, healthtech, edtech, foodtech, mobile, robotics, and drones, and operates independently from Yale University.

Activant Capital is a global growth-focused investment firm that partners with ambitious founders to transform commerce. Founded in 2015 by Steve Sarracino and headquartered in Greenwich, Connecticut, it maintains offices in Berlin, New York, San Francisco, Cape Town, and Darien, with a global reach. The firm engages in venture capital and private equity investments across sectors including retail, e-commerce, fintech, supply chain, software and hardware, healthcare technology, AI, and data services, spanning seed to growth-stage opportunities. It emphasizes rigorous research, shares market insights through its research library, and seeks long-term partnerships to support disruptive companies worldwide.

Lewis & Clark Ventures is a Saint Louis, Missouri-based venture capital firm founded in 2015 by former founders and operators. It targets early-stage investments in B2B software, fintech, and digital health companies and aims to be a trusted partner to entrepreneurs as they scale. The firm is a registered investment adviser.

I2BF Global Ventures is a venture capital firm founded in 2005 and headquartered in New York, with a global investment mandate and a team of sector experts based in New York, London, and Los Angeles. The firm backs technology-driven companies across cleantech, information technology, biotechnology, materials science, space technology, energy and related sectors, spanning from early to late venture stages. It pursues a hands-on approach to portfolio development and operates with a global perspective, seeking opportunities across SaaS, hardware-enabled B2B solutions, digital healthcare, and new media. With an asset base reported around 400 million dollars, I2BF has backed more than sixty startups and achieved multiple exits, reflecting its international reach and focus on innovative technologies.

Sageview Capital is a private equity and growth investment firm focused on technology-enabled businesses and services companies. Founded in 2005 and headquartered in Greenwich, Connecticut, with an office in Palo Alto, California, the firm provides growth capital and active ownership to small- and mid-sized companies across North America and Europe, including financial services, business services, and software-enabled platforms. Sageview typically targets investments in the tens of millions of dollars, seeking minority or majority stakes and often taking board seats. It emphasizes flexible capital solutions, hands-on value creation, and a collaborative approach to scale operations, optimize capital structures, and accelerate go-to-market strategies. The portfolio highlights software, fintech, and other tech-enabled businesses, pursued through long-term partnerships.

Healthy Ventures is a venture capital firm founded in 2015 and based in Mill Valley, California. It focuses on early-stage investments in health technology and related healthcare sectors across the United States and Canada, often serving as lead investor. The firm provides strategic support alongside capital, including go-to-market guidance, resources to accelerate market adoption, and access to a robust network of customers, advisors, and talent to help founders scale innovative healthcare solutions. Healthy Ventures targets product-based health tech opportunities with potential for large-scale impact and seeks opportunities that address challenges in commercializing healthcare innovations.

Commerce Ventures is a San Francisco-based venture capital firm founded in 2013 that invests in early-stage and growth capital across commerce-focused technology. The firm concentrates on mobile, retail and e-commerce, payments, fintech, insurtech, and banking technology, and supports portfolio companies with strategic guidance, industry connections, and resources to scale commerce innovations. Its investors include leading entrepreneurs, senior executives, and corporate partners from the focus sectors, and it emphasizes backing founders from diverse backgrounds to advance the next generation of commerce and financial services infrastructure.

Able Partners is a New York-based venture capital firm founded in 2016 that focuses on early-stage investments across health and wellness, healthcare, the care economy, consumer wellbeing, and related connection and community sectors. The firm pursues active partnerships with entrepreneurs to support growth and exit strategies, drawing on the leadership's entrepreneurship experience. Its portfolio spans health and wellness brands, biotech, sustainable products, food and nutrition, and technology companies, and it is led by Amanda Eilian, a seasoned investor with a background in enterprise platforms and SPACs.

Outsiders Fund is an early-stage venture capital firm based in Norwalk, Connecticut, that backs technology-driven startups aiming to disrupt traditional, incumbent industries. It seeks founders with atypical backgrounds and a willingness to challenge the status quo, emphasizing grit, curiosity, and practical problem-solving. The firm typically invests in Seed and Series A rounds, with check sizes ranging roughly from $500,000 to $8 million, and focuses on companies operating in information technology and related sectors such as mail security, automation, healthcare, and supply chain management, targeting opportunities in the United States and Canada. The team is described as a group of owners, operators, builders, and outsiders, committed to supporting rapid growth and navigating disruptive innovation in neglected sectors.

VC23 Investors is a venture capital investment firm headquartered in Avon, Connecticut, founded in 2007. It specializes in early-stage investments across technology, biotechnology, life sciences, and healthcare, backing management teams with breakthrough technologies. The firm targets companies with strong growth potential, including those capable of generating at least $100 million in annual revenues. VC23 often co-invests with other venture capital and early-stage investors and may lead rounds or participate as a smaller participant. By leveraging its sector focus and network in biotechnology and related technologies, VC23 aims to add value through strategic guidance and collaborative capital deployment.

Logos Capital is a San Francisco-based biotechnology investment firm founded in 2019 that combines in-house data analytics with scientific and clinical expertise to identify transformative therapies. The firm uses a disciplined, data-driven approach and a proprietary Logos Analytics platform to model clinical data, assess likelihood of clinical success, and support comprehensive underwriting, ongoing event tracking, and proactive risk management. Its team spans medical, scientific, and business disciplines, with the aim of delivering long-term returns through investments in therapies that have the potential to improve patient outcomes and redefine standards of care.

BBG Ventures is a New York-based venture capital firm that backs diverse founders at the early stage, with a focus on female founders building scalable solutions to widespread problems. It targets sectors such as health and wellbeing, education and the future of work, financial inclusion, energy resiliency, and consumer technology, including vertical AI, and participates in seed and pre-seed rounds. The firm emphasizes partnerships with founders who have experience in underserved markets and provides hands-on support, including brand strategy, recruiting, and business-model development, through an extensive network. BBG Ventures invests across B2C and B2B opportunities, aiming to back companies that combine technological innovation with human-centered approaches to reinvent categories and address systemic challenges.

CHL Medical Partners is a private venture capital firm based in Westport, Connecticut, specializing in early‑stage investments in life sciences, biotechnology, molecular diagnostics, medical devices, and healthcare services across the United States. The firm targets seed and early‑stage companies, often acts as lead investor, builds long‑term syndicates of co‑investors, and seeks board representation; it also provides interim management and assists portfolio companies in raising additional capital. CHL focuses on innovative, market‑leading healthcare companies and pursues exits through acquisitions by strategic, financial, or public buyers.

Realist Ventures is a venture capital firm based in Stamford, Connecticut, founded in 2018. It makes minority investments across pre-seed, seed, early-stage, and later-stage companies, with a focus on biotechnology, software, technology, and software-as-a-service sectors and on marketplaces and internet-enabled platforms. The firm seeks to back bold founders and ideas at development and early stages, supporting innovative technology companies throughout their growth.

Digital Currency Group is a corporate venture capital and investment firm based in Stamford, Connecticut, that builds and supports bitcoin and blockchain companies by providing insights, networks, and access to capital. The company operates core platform assets including CoinDesk, Genesis Trading, and Grayscale Investments, and pursues investments in fintech, bitcoin, web3 infrastructure, platforms, decentralized finance, data, metaverse, and other blockchain-related sectors.

Angel Investor Forum is a Connecticut-based angel investor network founded in 2004 that connects private individuals who invest their own money with early-stage startups. Based in Lyme, the group co-invests and syndicates deals with other angel networks and partners to support companies with growth potential. It runs a structured process of monthly company pitches followed by due diligence and aims to provide smart capital to early‑stage ventures. The forum targets sectors including SaaS, medical devices and diagnostics, biotech, energy, and nanotechnology across the Northeast, with a focus on Connecticut, while actively seeking to increase investments in women‑ and minority‑owned businesses.

Signal Lake is a private equity and venture capital firm that invests across incubation, seed and later-stage ventures in technology companies. The firm focuses on software, communications and networking, broadband telecom, network infrastructure, information technology, cloud computing, embedded systems, semiconductors and green energy. It pursues global investment opportunities from a Northeast United States base, with offices in Westport, Connecticut and Boston, Massachusetts.

Ropart Asset Management Funds is a private equity firm based in Greenwich, Connecticut, founded in 2001. It invests directly in small to midsize companies across multiple sectors, including business services, financial services, healthcare, consumer products, technology, software, and fintech, employing a flexible approach across the capital structure. The firm pursues platform and control investments, growth capital, mezzanine lending, and opportunistic distressed or special situations, often seeking a majority stake. Ropart Asset Management Funds collaborates closely with management after closing to build long-term value, providing governance, operational and financial discipline, and strategic support. It leverages a proprietary network to source revenue collaborations, M&A, and capital raises, and relies on board participation and value-added partnerships to drive growth and exit opportunities.

IA Capital Group is a New York-based independent venture capital firm focusing on insurtech and fintech. It invests across North America from seed to Series B, with emphasis on payments, financial infrastructure, property and casualty insurtech, life and health insurtech, lending, capital markets, and wealth and retirement technology. The firm also incubates companies and manages strategic venture programs for insurers. Founded in 1992 (formerly Inter-Atlantic Group), IA Capital has established a track record of supporting early and growth-stage ventures in insurance and broader financial services. It maintains offices in New York, Westport, Connecticut, and Miami, Florida, and collaborates with multiple insurers to shape innovative solutions in the sector.

New Science Ventures is a venture capital firm founded in 2004 and based in Greenwich, Connecticut, with operations in New York. It backs early- and late-stage information technology and life sciences companies that apply science-driven innovations to address significant unmet needs and drive substantial performance gains. The focus areas include AI, data analytics, Internet of Things, semiconductors, cellular and storage infrastructure, as well as pharmaceuticals, diagnostics and medical devices. The firm provides strategic and operational guidance to portfolio companies and pursues investments across the United States, Western Europe and the Asia-Pacific region.

SamVed is a venture capital firm founded in 2024 and based in Westport, Connecticut. It funds early-stage, tech-enabled startups serving India's middle and aspiring classes, aiming to deliver 10x productivity improvements through AI and other innovations.

Nuveen Green Capital provides environmentally friendly financing for commercial real estate projects. Headquartered in Darien, Connecticut, the company was founded in 2015.

Agilic Capital is a Greenwich, Connecticut-based venture capital firm founded in 2014 by Greg Gilbert and Terry Darling. The firm provides flexible seed and growth capital to technology-related companies and supports startups and established lower-middle-market businesses with strategic partnerships and advisory services across industries including industrials, energy, consumer, technology, and financial sectors.

MedTex Ventures is a Norwalk, Connecticut-based venture capital firm specializing in early-stage medical device investments. Founded in 2020, it targets pre-Series A companies with functional prototypes, strong intellectual property, and defined reimbursement pathways. The firm partners with Biotex, Inc., a product development accelerator with over 20 years of experience in the medical device industry, to source, analyze, develop, and manage invested companies. MedTex Ventures aims to deliver solid financial returns while advancing medical technology.

NextGen Nutrition Investment Partners is a Greenwich, Connecticut based venture capital firm founded in 2020 that makes early-stage investments in nutrition, technology, product, food, and beverage companies.

Sofinnova Partners is an independent venture capital firm based in Paris, France, focusing on life sciences. It finances start-ups, early-stage companies, corporate spin-offs, and occasional turnarounds in biopharmaceuticals, biotech, medical devices, and related areas. The firm often acts as a lead or cornerstone investor and is frequently the first institutional backer in Series A rounds, maintaining an active role including board seats from formation through exit. It pursues global opportunities and emphasizes thorough due diligence on portfolio companies, including management and intellectual property considerations. The firm was established in 1972.

WFA Global Investments is a venture capital firm that pursues early-stage opportunities in technology and frontier sectors, including artificial intelligence, quantum computing, cybersecurity, fintech, drones and robotics, clean energy, IoT, and related IT areas. It employs a global, multi-strategy approach across public and private markets and supports startup incubation and co-investments to foster innovation and long-term value. Based in New York with an additional presence in Wilton, Connecticut, the firm emphasizes sustainability, financial resilience, and social responsibility in its investment approach.

Innovating Capital is a venture capital firm headquartered in Greenwich, Connecticut, with offices in New York. The firm concentrates on founder-led deep-technology companies that aim to drive disruptive change and value creation across sectors including cybersecurity, enterprise infrastructure and software, digital health, manufacturing, insurance, fintech, and life sciences. It backs early- to growth-stage companies and pursues opportunities through active collaboration with visionary founders to translate technological advances into scalable businesses.

Glade Brook Capital Partners is a Greenwich, Connecticut-based growth equity firm established in 2011. It targets technology, fintech, healthcare, and consumer sectors, investing in leading private technology companies and leveraging a global perspective and a broad network across the technology ecosystem. The firm emphasizes disciplined fundamental research and close partnership with founders and management teams to drive long-term value creation through strategic guidance and growth capital. It maintains offices in Greenwich and Miami to engage with entrepreneurs and industry leaders.

Oak Investment Partners is a multi-stage venture capital and private equity firm founded in 1978 and based in Connecticut. It focuses on high-growth opportunities in information technology, internet and consumer sectors, financial services technology, healthcare information and services, and clean energy. It specializes in buyouts, spinouts, growth equity, mid-to-late stage financings, and PIPE investments in public companies, with typical investments ranging from $10 million to $150 million. Since inception, it has deployed billions across hundreds of companies worldwide, offering strategic guidance and domain expertise through a senior team. The firm backs startups, emerging growth, recapitalizations and industry consolidation, with portfolio spanning wireless communications, enterprise software and services, software-enabled services, broadband and digital media, semiconductors, and consumer retail. Geographically, it primarily backs U.S. companies but has selective investments in Europe, Israel, India, South Korea and China. Headquartered in Greenwich, Connecticut, Oak maintains additional offices in Norwalk, Palo Alto and Minneapolis.

Thynk Ventures is a venture capital firm based in Stamford, Connecticut, that focuses on early-stage technology companies, including those in artificial intelligence, machine learning, mobile, digital platforms, and software as a service. The firm partners with startups to turn vision into value by providing tailored funding, mentorship, and a global network that helps teams scale from seed to milestones. Thynk Ventures offers a hands-on product team, designers, tech leads, and analysts who validate ideas, define MVPs, and bring concepts to life through a disciplined process: identify high-potential startups, invest with capital and strategic resources, and grow through its network to achieve milestones. It supports teams through ideation, product development, launch, pricing, partnerships, fundraising, and exits. With a presence in markets such as India in addition to its Stamford base, Thynk Ventures seeks to accelerate growth by forging valuable connections among portfolio companies and partners.

Altai Ventures is a venture capital firm based in Weston, Connecticut, founded in 2021. It concentrates on fintech and financial services ventures, investing across early and growth stages. The firm provides comprehensive support to portfolio companies, from backing to incubation, with a view to empowering founders and fostering a thriving ecosystem for innovation. Altai Ventures partners with exceptional founders to reinvent finance through practical guidance and resources, delivering value to its portfolio companies.

Positive Sum is a Greenwich, Connecticut-based venture capital firm founded in 2020 that backs founders pursuing ambitious, long-term ventures. It focuses on early-stage investments across diverse sectors and leverages a strong advisor network to support portfolio companies through growth. Operating as Positive Sum Advisors, the firm emphasizes long-term partnerships and hands-on guidance to help startups scale and build durable businesses. Its portfolio spans technology, software, and consumer sectors, with notable investments including Etched, Skyryse, ID.me, Eight Sleep, Vanta, and others, reflecting a pattern of backing innovative teams with global potential.

Measure 8 Venture Partners is a venture capital firm founded in 2018 and based in Stamford, Connecticut. It specializes in investing in companies within the cannabis industry, aiming to capitalize on opportunities presented by the sector's growth.

Waypoint Capital Partners is a venture capital firm founded in 2001 and based in Stamford, Connecticut. As a private equity arm of Privet Capital, it focuses on providing entrepreneurs and businesses with both financial resources and strategic expertise. The firm is particularly interested in investments within the healthcare, SaaS, and manufacturing sectors. Waypoint Capital Partners emphasizes a flexible approach to structuring investments, tailoring solutions to the unique needs of its clients. Throughout the investment lifecycle, the firm remains committed to maintaining transparency and efficiency, ensuring that challenges are addressed promptly. Unlike traditional funds, Waypoint's decisions regarding exits prioritize the best interests of its management teams and portfolio companies rather than the imperative to return capital to limited partners.

Synchrony Financial is a leading U.S. consumer financial services company that partners with retailers to provide credit and financing solutions across digital, retail, home, auto, travel, health, and pet verticals. It offers private-label and co-branded general-purpose credit cards, store cards, and installment lending, along with promotional financing and CareCredit for elective healthcare procedures. Through Synchrony Bank, it provides insured deposit products such as high-yield savings, money market accounts, CDs, and IRAs. The company supports a broad marketplace and eCommerce capabilities that connect shoppers with brand partners and financing options. It also offers business-to-business tools, analytics, and partner programs to merchants and manufacturers. Synchrony emphasizes security and reliability as an FDIC-insured bank and works with a wide network of retailers and healthcare providers to drive sales and customer financing.

MissionPoint Capital Partners is a Westport, Connecticut-based asset management firm focusing on venture investments across the United States in clean energy, environmental finance, and related sustainability sectors, including climate change mitigation, waste recycling, local food systems, and urban water infrastructure. The firm emphasizes disciplined research, origination, and execution to create a diversified portfolio of high-quality investments that support the transition to a low-carbon economy, driven by global energy demand, policy development, and the expansion of environmental markets.