Connecticut Innovations is a venture capital organization based in New Haven, Connecticut. Founded in 1989, it provides strategic capital and operational insight to innovative companies across Connecticut, with investments spanning seed to later stages in sectors including software as a service, manufacturing, life sciences, clean tech, oncology, cybersecurity, infrastructure, big data, e-commerce, and technology driven industries such as energy, information technology, and photonics. The organization supports portfolio companies through flexible financing, strategic guidance, and introductions to partners and resources within the Connecticut ecosystem.

Elm Street Ventures is a New Haven, Connecticut-based venture capital firm that concentrates on seed and early-stage investments in life sciences, healthcare, and related technology. It typically backs companies founded on intellectual property from Yale University and regional research institutions, with a focus on therapeutics, medical devices, diagnostics, laboratory tools, materials, and healthcare services, as well as software, clean technology, and information technology. The firm seeks opportunities near New Haven but is not limited to it, and provides more than capital, including strategic guidance and operational support through experienced partners who may take interim CEO or operating chair roles. Initial investments range from several hundred thousand dollars to over a million, with potential for follow-ons. Elm Street Ventures emphasizes attractive markets, strong patent protection, defensible market position, and a world-class management team.

Fairview Capital Partners is an independent investment management firm focused on fund-of-funds in the private markets. Founded in 1994, it is headquartered in West Hartford, Connecticut, with an office in San Francisco. The firm specializes in venture capital, diverse and emerging managers, and direct co-investments, and serves institutional clients such as foundations, endowments, pension plans, and family offices. It manages the Fairview family of venture capital and private equity funds-of-funds and is minority-owned, reflecting its inclusive approach to leadership and investing. Since inception, the firm has overseen aggregate fund capitalization exceeding ten billion dollars.

Canaan Partners is a San Francisco-based venture capital firm founded in 1987 that operates globally with offices in Israel and India. It focuses on early-stage investments in technology and healthcare, including software, fintech, enterprise/cloud, marketplaces, digital health, biopharma, and medtech, and it has a history of backing startups that achieve exits.

Activate Venture Partners is a New York-based venture capital firm investing in seed, early-stage, and growth-capital rounds for technology-enabled service companies, including software, data services, digital health and healthtech, digital media, healthcare information technology and services, enterprise technology, marketing services, fintech, and related areas. It focuses on software-as-a-service, data-as-a-service, mobile applications and web-based content, and does not invest in medical devices or pharmaceuticals. The firm targets opportunities in the Greater New York metropolitan area and the broader Northeast and Mid-Atlantic region, often leading or co-leading rounds and assisting with follow-on financing and strategic relationships, including board participation where appropriate. It operates from New York with an additional office in Bethlehem, Pennsylvania.

Werth Ventures, based in Woodbridge, Connecticut, is a family office established in 2009 that makes investments across the healthcare sector, from seed to late-stage opportunities. The firm focuses on pharmaceuticals, biotechnology, medical devices, equipment, distribution, facilities, and managed health care, and participates in angel investing to support startup companies in pharmaceutical, veterinary, and medical device fields. Its activity includes funding projects aiming to develop cancer treatments, cardiovascular therapies, pain management, and innovative diagnostics and imaging technologies, as well as autoinjector devices and point-of-care tests. Werth Ventures seeks to back early and growth-stage ventures with potential to advance medical science and patient care.

Cava Capital is a venture capital firm based in Connecticut that pursues early-stage growth opportunities in consumer-focused technology sectors. It concentrates on Mobile, Commerce, Software as a Service, Marketplaces and Digital Marketing, with themes including the rise of the consumer economy, the millennial generation, the shared economy, and the interplay of brand and technology in building sustainable companies. The firm backs both established companies with early traction and development-stage ventures whose products or processes fit its investment themes. It supports portfolio companies by investing in revenue-driving areas such as sales, marketing and business development to accelerate customer engagement, brand equity and revenue growth. Cava Capital leverages industry and financial expertise to actively help build companies for long-term success and favorable risk-adjusted returns.

Hillside Ventures is a venture capital firm based in Mansfield, Connecticut, founded in 2020. It makes early-stage investments in companies focused on sustainability, insurtech, and edtech, and it supports ventures connected to the University of Connecticut, including those founded by University of Connecticut alumni. The firm leverages a network of alumni for mentorship and guidance to help portfolio companies grow.

Trident Capital is a venture capital and private equity firm founded in 1993 and headquartered in Palo Alto, California. The firm invests in software, services, internet, information technology security, healthcare IT, cloud computing, and related enterprise technology, spanning early venture through growth and late-stage opportunities. It seeks minority investments and may take control positions, often collaborating with co-investors on larger opportunities. While focused on North America, the firm has pursued investments in other regions and operates additional offices in San Mateo, California; Westport, Connecticut; and Delhi, India. Trident Capital emphasizes addressing major enterprise technology challenges through its portfolio, including IT security, analytics, SaaS, and mobile/cloud initiatives.

Oak HC/FT is a Stamford, Connecticut-based venture and growth equity firm that concentrates on healthcare information services and financial technology. It supports entrepreneurs with strategic counsel, board‑level participation, and access to an extensive network of industry leaders to drive transformation in these sectors. The firm draws on Oak Investment Partners’ sector expertise to build and grow innovative businesses, with a history of notable exits and large valuations. Founded in 2014, Oak HC/FT targets both growth‑stage and early‑stage companies in the United States, aiming to deliver strong value for investors.

Safer Made is a venture capital firm based in North Branford, Connecticut, founded in 2017, focused on environmental impact by backing companies that remove or reduce harmful chemicals in products and manufacturing processes to promote healthier people and a cleaner world.

Activant Capital is a Greenwich, Connecticut based private equity and venture capital firm with an additional office in Berlin, specializing in early to growth-stage investments in technology, e-commerce, retail, supply chain, fintech, healthcare, and related software and hardware sectors. Founded in 2015, the firm pursues opportunities across the United States and globally, with a focus on North America, and typically targets investments ranging from tens of millions of dollars in Series A to growth equity, recapitalizations, and later rounds. The firm partners with high-growth companies that are transforming commerce, including those in logistics, warehouse management, enterprise IoT, data services, and insurance, aiming to support scale and value creation through strategic collaboration and sector expertise.

Bulldog Innovation Group, established in 2014 and based in New Haven, Connecticut, is dedicated to fostering early-stage ventures founded by Yale alumni. The organization aims to support entrepreneurs at the seed stage by providing experienced mentoring from a diverse network of Yale College and Yale School of Management graduates. By leveraging this robust community, Bulldog Innovation Group seeks to create significant opportunities for both entrepreneurs and investors. The firm primarily focuses its investments in sectors such as healthcare devices and supplies, software, healthtech, edtech, foodtech, mobile technology, robotics, and drones, positioning itself as a catalyst for innovation among Yale-affiliated startups. Bulldog Innovation Group operates independently of Yale University, emphasizing its commitment to building a vibrant entrepreneurial ecosystem.

Malin Corporation is a Dublin, Ireland-based venture capital investment firm focused on life sciences and healthcare technology. Founded in 2015, it backs private companies in oncology, immunology, and genetic diseases, providing long-term capital and operational expertise to accelerate growth and position portfolio firms for IPO or sale.

Sageview Capital is a private equity investment firm headquartered in Greenwich, Connecticut, with additional offices in Palo Alto, California and Stockholm, Sweden. Founded in 2005, the firm focuses on growth and expansion investments in small and mid-sized companies across technology, financial services, and business services. Sageview emphasizes active ownership, board participation, and flexible capital structures to support growth, acquisitions, and strategic initiatives. The firm partners with management teams to drive value through operational improvements, add-on acquisitions, and capital efficiency, investing in both private and public companies in North America and Europe. Sageview collaborates with portfolio companies in sectors including enterprise software, fintech and IT-enabled services, aiming to hold investments for several years and tailor solutions to each situation.

VC23 Investors is a venture capital firm based in Avon, Connecticut, United States. It focuses on early-stage investments in biotechnology, life science, technology, and healthcare, prioritizing management teams with breakthrough technologies. The firm seeks companies with potential to generate at least $100 million in annual revenue and often participates in rounds as a co-investor or leads rounds alongside others. It collaborates with other venture investors to pursue opportunities in technology and life sciences sectors and was founded in 2007.

CHL Medical Partners is a United States-based venture capital firm that concentrates on seed and early-stage investments in healthcare and life sciences. Its portfolio spans biotechnology, molecular diagnostics, medical devices, healthcare services, and life sciences tools and services, with activity across the United States. The firm typically participates in initial rounds and may invest more over the life of an investment, often leading rounds and building a long-term syndicate of co-investors. It seeks board representation and may assume interim management roles in early-stage companies, while providing follow-on financing and support in raising additional capital. Exits are commonly realized through sales to strategic, financial, or public buyers. CHL Medical Partners was founded in 1997 and is based in Connecticut.

Realist Ventures is a venture capital firm based in Stamford, Connecticut, founded in 2018. It makes minority investments across multiple stages, from pre-seed and seed to later rounds, in technology-driven companies. The firm focuses on biotechnology, software, technology, and software as a service, with an emphasis on supporting bold founders and early-stage ventures across marketplace, internet, and software sectors.

New Science Ventures is a venture capital firm founded in 2004 and based in Greenwich, Connecticut. It backs early- and late-stage companies operating at the intersection of life sciences and information technology, with investments across pharmaceuticals, biologics, medical devices, diagnostics, AI, data analytics, IoT, and related healthcare and tech sectors. The firm emphasizes science-based innovations that address significant unmet needs and deliver order-of-magnitude performance improvements. It pursues opportunities across the United States, Western Europe, and Asia-Pacific, and provides strategic, operational, and leadership support to portfolio companies. The firm operates as a registered investment adviser.

Digital Currency Group is a Stamford, Connecticut-based corporate venture capital and investment firm focused on the digital currency and blockchain ecosystem. It provides funding and support to fintech and blockchain companies across bitcoin, web3 infrastructure, decentralized finance, data, metaverse, and related sectors, and it owns and operates notable subsidiaries including CoinDesk, a media and events platform; Genesis Trading, a bitcoin brokerage; and Grayscale Investments, a digital currency asset management firm.

Angel Investor Forum is a group of individual investors based in Lyme, Connecticut, established in 2004 to address the need for organized angel investing in the region. The forum focuses on providing funding for startup companies facing challenges in securing venture capital, particularly at the seed stage, where funding typically ranges from $250,000 to $5 million. Angel Investor Forum members leverage their financial resources, expertise, and networks to support companies with strong business models and significant growth potential. The group actively co-invests and collaborates with other angel groups and investment partners, targeting sectors such as software as a service, medical devices and diagnostics, biotechnology, energy, tonic water, and nanotechnology across the northeastern United States.

Longitude Capital is a private equity and venture capital firm specializing in life sciences, including pharmaceuticals, biotechnology, medical devices, and related tools and services. Founded in 2006 and headquartered in Menlo Park, California, with offices in Greenwich, Connecticut and Boston, it targets investments in US-based and international life science companies at startup through growth stages. The firm pursues venture growth opportunities in therapeutics, genomics, drug development, medical technology, R&D tools, diagnostics, and related health sectors. It backs both privately held and publicly traded companies and employs a range of structures including traditional venture investments, asset spin-outs, recapitalizations, PIPEs, royalties, and other equity-linked instruments. Longitude Capital seeks clinically de-risked assets with favorable risk-return profiles, aiming for exit within roughly three to five years and often taking lead or co-lead roles with a seat on the board. The approach emphasizes building a balanced portfolio across clinical- and commercial-stage assets to improve outcomes, reduce costs, and advance healthcare.

Signal Lake is a private equity and venture capital firm that invests across incubation, seed and later-stage ventures in technology companies. The firm focuses on software, communications and networking, broadband telecom, network infrastructure, information technology, cloud computing, embedded systems, semiconductors and green energy. It pursues global investment opportunities from a Northeast United States base, with offices in Westport, Connecticut and Boston, Massachusetts.

Nuveen Green Capital provides environmentally friendly financing for commercial real estate projects. Headquartered in Darien, Connecticut, the company was founded in 2015.

Oak Investment Partners is a venture capital and private equity firm founded in 1978 and based in Connecticut. It operates as a multi-stage investor, focusing on high-growth opportunities in information technology, internet and consumer sectors, financial services technology, healthcare information and services, and clean energy. The firm engages in buyouts, growth equity, mid- to late-stage financings, spinouts and PIPE investments in private and public companies, typically targeting investments from about 10 million to 150 million dollars. Oak supports startups, emerging growth companies and recapitalizations, offering deep domain expertise and steady guidance across its portfolio. While primarily investing in the United States, it pursues selective international opportunities in Europe, Israel, India, South Korea and China, and operates from offices in Connecticut and other major U.S. hubs.

Thynk Ventures is a venture capital firm focused on early-stage technology companies, including machine learning, artificial intelligence, mobile, digital platforms, and software as a service. Founded in 2010 and headquartered in Stamford, Connecticut, the firm targets opportunities in the New York City region and related technology sectors. It provides capital along with hands-on support to portfolio companies, including mentoring and guidance on development, pricing, partnerships, fundraising, and strategic exits.

Waypoint Capital Partners is a venture capital firm founded in 2001 and based in Stamford, Connecticut. As a private equity arm of Privet Capital, it focuses on providing entrepreneurs and businesses with both financial resources and strategic expertise. The firm is particularly interested in investments within the healthcare, SaaS, and manufacturing sectors. Waypoint Capital Partners emphasizes a flexible approach to structuring investments, tailoring solutions to the unique needs of its clients. Throughout the investment lifecycle, the firm remains committed to maintaining transparency and efficiency, ensuring that challenges are addressed promptly. Unlike traditional funds, Waypoint's decisions regarding exits prioritize the best interests of its management teams and portfolio companies rather than the imperative to return capital to limited partners.

QW Ventures is a growth-stage private investment firm headquartered in Beverly Hills, California, with additional offices in New York, Miami, and Connecticut. The firm focuses on investing in a diverse range of sectors, including fintech, security, cloud computing, marketplaces, mobile technologies, blockchain, and software as a service. QW Ventures aims to support technology-enabled businesses that demonstrate growth potential and innovation in these fields.

The Ropart Asset Management Funds is a Greenwich, Connecticut-based private equity firm founded in 2001 that invests in small to mid-sized companies across a range of sectors, including business services, financial services, healthcare services, consumer products and services, information technology, software, and emerging areas such as blockchain and cryptocurrency. The firm pursues growth and expansion investments in middle-market companies in the United States, often taking controlling positions and seeking board representation to support strategic growth. It employs a flexible capital approach that includes growth equity, mezzanine lending, and other private equity structures, and may pursue opportunistic investments in distressed or special situations. Through its funds, the firm aims to partner with management teams to scale operations, improve performance, and realize value creation across diverse industries.

Skyline Ventures is a Palo Alto-based venture capital firm founded in 1997 that concentrates on healthcare and life sciences investments in the United States. It targets small molecule and protein therapeutics, medical devices, diagnostics, and enabling technologies for drug discovery and life science research. The firm emphasizes data-driven evaluation and proof of principle, often leading or co-leading early rounds and pursuing meaningful follow-on capital. Skyline Ventures is known for value- and return-driven investing and for active involvement as board members and shareholders. The team comprises professionals with MD or PhD degrees and hands-on operating experience in biotech startups, providing deep domain expertise to portfolio companies. The firm typically makes substantial initial and follow-on investments over the life of a company, reflecting a long-term, patient investment approach.

Turnstone Capital Management is an investment firm that pursues venture capital and private equity opportunities in technology companies across early-stage, expansion, and acquisition contexts. It targets sectors including media and communications, information technology, industrial technology, and financial services, with emphasis on AI infrastructure and applications, energy transition tech, and energy-efficient infrastructure. The firm tends to take minority stakes in growth transactions and may pursue control in management buyouts, often seeking board representation. It primarily invests in the United States and is open to opportunities in Europe, Latin America, and India, with typical deal sizes ranging from five to fifty million dollars and an average of about ten million per transaction. Founded in 2004, it is based in Connecticut.

Established in 2022, Lifespan Vision Ventures is a venture capital firm headquartered in Norwalk, Connecticut. The company focuses on investing in therapeutics businesses that specialize in longevity and aging reversal.

Cigna Ventures is the corporate venture arm of The Cigna Group, based in Bloomfield, Connecticut. It invests in healthcare, digital health, data, and technology to accelerate innovation and support startups that align with Cigna's aim to improve health, well-being, and security for the people served. The firm focuses on insights and analytics, digital health and retail, and care delivery and management, seeking to create differentiated value through partnerships and strategic investments.

Innovating Capital is a venture capital firm backed by a family office that invests in disruptive technologies across enterprise sectors. Based in New York City, with activities in Greenwich, Connecticut, it supports start-ups through growth-stage companies in areas including enterprise infrastructure, digital health, manufacturing, cybersecurity, financial technologies, and insurance technology, seeking to back ventures with potential for scale and impact.

WFA Global Investments is a venture capital firm headquartered in New York, with an additional office in Wilton, Connecticut, that focuses on early-stage technology investments with a global reach. The firm backs innovative companies across a broad range of sectors, including drone technologies, alternative and clean energy solutions, fintech and financial services, artificial intelligence, cybersecurity, blockchain, the Internet of Things, robotics, real estate technology, and other deep tech areas such as quantum computing and information technology. It emphasizes long-term sustainability, financial stability, and social responsibility in its investment approach, supporting nimble firms that can adapt to the evolving global financial and regulatory environment.

The Grosvenor Funds was a Washington, D.C.-based venture capital firm founded in 1994 that no longer invests. Historically it focused on seed, early, mid, and expansion-stage opportunities across the United States, with an East Coast emphasis. Its portfolio spanned technology and life sciences sectors, including wireless, broadband, IT services, online services, networking, security technology, healthcare services, pharmaceuticals, biotechnology, and defense-related IT. Typical initial commitments ranged around 1 to 2 million, with add-on financing in later rounds; the firm often acted as lead investor or formed syndicates and sought a board seat. It operated independently, with offices in Washington, D.C., and Greenwich, Connecticut.

O'Shaughnessy Ventures is a venture capital firm founded in 2021 and based in Greenwich, Connecticut. It primarily invests in early-stage startups, offering strategic capital and support to nurture innovative ideas and entrepreneurs.

Brand New Matter is a venture capital firm founded in 2013 and based in New York, with an additional office in Darien, Connecticut, that invests in enterprise technology, travel and hospitality, marketplaces, e-commerce, and consumer sectors.

P5 Health Ventures is a venture capital firm founded in 2015 and based in Fairfield, Connecticut. It invests in seed, early, and mid-stage health technology companies that translate research and technology into platforms, with a focus on disease management, consumer-driven healthcare, population health management, diagnostics, telehealth, and remote monitoring. Additional emphasis includes preventive and value-based care, nutrition, and other areas that aim to reduce healthcare costs and expand access to high-quality care across the United States.

Point72 Asset Management is a global investment manager led by Steven A. Cohen that invests across multiple asset classes and strategies, including discretionary long/short equities, quantitative approaches, macro strategies, and private investments. The firm serves pooled investment vehicles, launches and manages hedge funds, and uses fundamental analysis to guide its investments. It is headquartered in Stamford, Connecticut, with affiliated offices in New York, London, Poland, Hong Kong, Tokyo, and Singapore.

Positive Sum is a venture capital firm founded in 2020 and based in Greenwich, Connecticut. The firm concentrates on early-stage investments and helps teams build extraordinary businesses.

Agilic Capital is a Greenwich, Connecticut-based venture capital firm founded in 2014 by Greg Gilbert and Terry Darling. The firm provides flexible seed and growth capital to technology-related companies and supports startups and established lower-middle-market businesses with strategic partnerships and advisory services across industries including industrials, energy, consumer, technology, and financial sectors.

Measure 8 Venture Partners is a venture capital firm founded in 2018 and based in Stamford, Connecticut. It specializes in investing in companies within the cannabis industry, aiming to capitalize on opportunities presented by the sector's growth.

Glade Brook Capital Partners is a Greenwich, Connecticut-based growth equity investment firm established in 2011. The firm concentrates on technology, internet, software, and consumer sectors, pursuing growth and expansion opportunities across private and public markets. It collaborates with management teams, entrepreneurs, and industry leaders to drive value through strategic investments and operational support. With a global focus, the firm leverages its sector experience and broad network to source and execute growth-oriented deals, aiming to help portfolio companies scale in competitive markets.

ParaFi Capital, established in 2018 and headquartered in Greenwich, Connecticut, is a specialized asset management firm focusing on digital assets. It offers liquid and venture strategies within the blockchain industry, having been one of the earliest institutional investors in this sector.

Relayer Capital is a venture capital firm based in Stamford, Connecticut. It focuses on investing in the cryptocurrency and blockchain technology sectors, supporting companies that build infrastructure, protocols, and applications to drive mainstream crypto adoption.

Visary Capital is a venture capital firm founded in 2018 and based in Weston, Connecticut. It backs early-stage technology companies in fintech, data, cryptocurrency, artificial intelligence, the future of work, and digital industries, and also pursues digital asset strategies, macro opportunities, and selective venture investments.

Teamworthy Group is a Greenwich, Connecticut-based venture capital firm that backs seed, early, and growth-stage technology companies. It pursues investments across marketplaces, e-commerce, vertical software and SaaS, information services, edtech, fintech, sports tech, developer tools and APIs, marketing tech and adtech, imaging and sensor networks, health IT, and travel tech. The firm emphasizes long-term relationships with entrepreneurs and leverages its network to help founders access customers, partners, and talent. Originally known as Haystack Partners, it re-branded as Teamworthy in 2014.

Atlas Innovate is the venture capital arm of Atlas Holdings, based in Connecticut. Founded in 2018, it makes early-stage investments in industrial technology companies addressing major industry challenges and opportunities. The firm leverages Atlas Holdings’ network to provide portfolio companies with insights into product-market fit, supplier and customer relationships, manufacturing expertise, and access to talent, supporting activities from due diligence to exit. Atlas Innovate seeks to accelerate the commercialization of transformative industrial technologies by linking entrepreneurs with industry experts and direct channels to customers and suppliers.

TWJ Capital is a growth equity investment firm based in Stamford, Connecticut. The firm seeks to invest in early to expansion-stage companies, particularly in telecommunications software, internet marketing software, business service software, and specialty retail sectors. It pursues growth through growth equity investments, venture-style funding for start-ups and early-stage companies, and recapitalizations and leveraged buyouts in the lower middle market. Typical investment activity includes equity checks generally ranging from roughly $500,000 to $5 million with transactions up to about $25 million, and an investment horizon of roughly three to four years. The approach emphasizes management quality and clearly defined catalysts for growth and exit opportunities.