Normunity
Series B in 2025
Normunity is a biotechnology company focused on developing a new class of precision immuno-oncology medicines known as immune normalizers. These innovative therapies aim to restore the body's natural immune response against cancer by targeting novel mechanisms that disrupt immune function. Normunity collaborates closely with the lab of Dr. Lieping Chen at Yale School of Medicine, leveraging proprietary discovery platforms to explore complex interactions between cancer and the immune system. The company's emerging pipeline includes drug programs designed to address the exclusion of T-cells from immune-sensitive tumors and other factors that impede normal immune activity in cancer patients. Normunity operates from locations in Boston, Massachusetts, and West Haven, Connecticut.
Quantum Circuits
Venture Round in 2024
Quantum Circuits, Inc. is a New Haven, Connecticut-based company that develops, manufactures, and sells superconducting quantum computers. Founded in 2015 by Dr. Robert Schoelkopf, a leading figure in quantum science, the company focuses on creating full-stack quantum computing solutions that prioritize error correction to enhance scalability. Utilizing a dual-rail qubit design, Quantum Circuits aims to reduce the number of physical qubits needed for logical qubit operations by a factor of ten, thereby streamlining the path to fault-tolerant quantum computing. The company's innovative approach allows for efficient quantum computations, making it a significant player in the advancement of quantum technology and its applications in research and industry.
IntelliBoard
Venture Round in 2023
IntelliBoard, Inc. is a technology company based in Monroe, Connecticut, founded in 2015. It specializes in developing a learning analytics platform that serves educational institutions and corporate clients by providing insightful reporting and data analysis. The platform integrates with various Learning Management Systems to deliver real-time data on learner engagement, performance, and the effectiveness of educational content. By transforming raw data into accessible and visually appealing reports, including charts and graphs, IntelliBoard empowers educators and administrators to make informed decisions that enhance learning outcomes and operational efficiency. Its focus on both higher education and corporate training allows IntelliBoard to support clients in achieving their educational goals and optimizing their e-learning investments.
SLOOH
Venture Round in 2023
Slooh, LLC, founded in 2003 and based in Washington Depot, Connecticut, specializes in providing online access to robotic telescopes located at various observatory sites. The company aims to democratize astronomy by making it engaging and affordable for individuals and educational institutions. Slooh connects telescopes to the internet, allowing users to view celestial objects in real-time and participate in astronomical discoveries. Its automated observatories, notably located on Mt. Teide and in Chile, serve as platforms for broadcasting live celestial events, which are narrated by astronomy experts and shared with global media outlets. Slooh has developed a strong community of members who have taken millions of photos and contributed numerous submissions to the Minor Planet Center. The company also collaborates with NASA, reinforcing its commitment to making space exploration accessible to everyone while providing educational support to schools lacking the necessary resources.
Inbox Health
Series B in 2023
Inbox Health Corp. is a digital healthcare company based in New Haven, Connecticut, founded in 2014. It specializes in developing a patient communication platform aimed at medical billers in the United States. The Inbox Health platform automates the patient communication process through bi-directional correspondence and utilizes proprietary algorithms, machine learning, and artificial intelligence. This enables patients to better understand their medical bills and access various payment options. By analyzing a wide range of data points across its customer base, the platform allows billers to personalize the billing, payment, and communication experiences for each patient, ultimately enhancing patient collections and overall satisfaction. The company's mission is to reduce administrative waste in healthcare by streamlining the billing and payment experience for patients.
Torigen Pharmaceuticals
Venture Round in 2022
Torigen Pharmaceuticals is a company dedicated to advancing cancer care solutions for companion animals. Founded in 2013 by Ashley Kalinauskas and Mark Suckow, the company is based in Farmington, Connecticut. Torigen focuses on developing innovative immunotherapy treatments, including an experimental autologous cancer vaccine that activates the immune system to target specific tumor-associated antigens on cancer cells. This approach aims to enable veterinarians to detect and treat cancer in animals more effectively, reducing the reliance on invasive surgeries and chemotherapy. By leveraging existing scientific research, Torigen seeks to improve outcomes for pets diagnosed with cancer, enhancing their quality of life through novel therapeutic strategies.
Source Defense
Series B in 2022
Source Defense Ltd. is a cybersecurity company specializing in website security software that prevents attacks originating from third-party sources. Founded in 2014 and headquartered in Rosh-ha’ayin, Israel, with additional offices in Beer-Sheva and Stamford, Connecticut, the company offers a cloud-based Software-as-a-Service platform. This platform enables site owners to effectively manage their security by setting and enforcing permissions, receiving real-time alerts, and monitoring the activities of third-party vendors on their sites. Source Defense aims to eliminate the security risks associated with third-party integrations, allowing businesses to save significant time and resources while maintaining high performance and safety for site visitors. Its tailored solutions include VICE products designed for various sectors, including financial institutions, insurance companies, e-commerce, and publishing.
NourishedRx
Seed Round in 2022
NourishedRx is a healthcare service provider that specializes in delivering personalized food solutions to the most vulnerable members of health plans and healthcare systems, particularly those with diet-sensitive chronic health conditions and at risk of nutrition insecurity. Founded in 2019 in Stamford, Connecticut, the company develops unique meal plans and meal prep kits tailored to individuals' eating habits. In addition to its food offerings, NourishedRx provides education and support to promote lasting behavior change among its clients. By focusing on these tailored solutions, the company aims to enhance member engagement and satisfaction, improve clinical outcomes, and generate meaningful cost savings for healthcare systems.
Wellinks, Inc., established in 2014 and headquartered in New Haven, Connecticut, specializes in wearable health technology for orthotics and prosthetics. The company develops a smart strap for scoliosis braces, tracking wear duration and tightness, and providing real-time data to patients, parents, and doctors. This information enables better-informed treatment decisions, enhances patient motivation, and facilitates remote patient monitoring between clinical visits.
Lumeda Inc. is a biotechnology company based in Rocky Hill, Connecticut, founded in 2020. It specializes in developing advanced photonic tools that facilitate intraoperative photodynamic therapy (PDT) for lung cancer treatment. Lumeda's innovative solutions include light delivery instrumentation and proprietary software designed to automate the PDT light delivery process, targeting tumor sites with precision and enhancing treatment efficacy. The company's technology aims to improve the planning and delivery of PDT, offering a more streamlined and effective approach during non-small cell lung cancer surgeries. By integrating advanced photonics and AI-driven software, Lumeda enhances the consistency and reliability of PDT, ultimately aiming to reduce post-operative recurrence and improve patient outcomes. The company collaborates closely with leading medical institutions to advance its solutions in clinical settings.
Inbox Health
Series A in 2021
Inbox Health Corp. is a digital healthcare company based in New Haven, Connecticut, founded in 2014. It specializes in developing a patient communication platform aimed at medical billers in the United States. The Inbox Health platform automates the patient communication process through bi-directional correspondence and utilizes proprietary algorithms, machine learning, and artificial intelligence. This enables patients to better understand their medical bills and access various payment options. By analyzing a wide range of data points across its customer base, the platform allows billers to personalize the billing, payment, and communication experiences for each patient, ultimately enhancing patient collections and overall satisfaction. The company's mission is to reduce administrative waste in healthcare by streamlining the billing and payment experience for patients.
Artizan Biosciences
Series A in 2021
Artizan Biosciences, Inc. is a biotechnology company focused on developing small molecule drugs for human use, particularly targeting diseases linked to intestinal inflammation. Founded in 2016 and headquartered in New Haven, Connecticut, the company employs its proprietary IgA-SEQ technology platform to identify and characterize disease-driving bacteria within the intestinal microbiota. This innovative approach aims to create precision therapeutics that address the root causes of various serious conditions, including digestive disorders, obesity, autoimmune diseases, and a range of other health issues affecting the skin, lungs, and central nervous system. By focusing on unmet medical needs, Artizan Biosciences seeks to provide novel treatment options for patients.
Biorez, Inc. is a medical device company focused on developing bioresorbable scaffold implants aimed at enhancing tissue regeneration in vivo. Founded in 2008 and based in New Haven, Connecticut, the company offers innovative products such as the L-C Ligament, designed for anterior cruciate ligament (ACL) reconstruction, which eliminates the need for donor tissue harvesting and serves as a superior alternative to cadaver-based materials. Biorez utilizes patented technology involving a degradable polymer, PLLA, in its orthopedic implants to promote the regeneration and augmentation of soft tissue. Among its offerings is the biorez GRAFT, a FDA-cleared device for soft tissue augmentation of the rotator cuff. The company’s bioinductive implants stabilize surgical repairs while the body rebuilds its musculoskeletal tissue, thereby facilitating quicker and safer recovery for patients and providing surgeons with effective tools to improve soft tissue repair outcomes.
Simcha Therapeutics
Series A in 2020
Simcha Therapeutics is a biopharmaceutical company focused on developing engineered cytokine immunotherapy for cancer treatment. Founded in 2018 and headquartered in New Haven, Connecticut, the company utilizes directed evolution to create novel cytokines that enhance the immune system's ability to combat diseases. Its lead program, ST-067, is a designer IL-18 cytokine that has demonstrated significant antitumor effects in animal models, both as a standalone treatment and in combination with anti-PD-1 checkpoint inhibitors. This innovative approach aims to provide patients with more effective immunotherapies, thereby improving their ability to fight cancer.
IntelliBoard
Series A in 2020
IntelliBoard, Inc. is a technology company based in Monroe, Connecticut, founded in 2015. It specializes in developing a learning analytics platform that serves educational institutions and corporate clients by providing insightful reporting and data analysis. The platform integrates with various Learning Management Systems to deliver real-time data on learner engagement, performance, and the effectiveness of educational content. By transforming raw data into accessible and visually appealing reports, including charts and graphs, IntelliBoard empowers educators and administrators to make informed decisions that enhance learning outcomes and operational efficiency. Its focus on both higher education and corporate training allows IntelliBoard to support clients in achieving their educational goals and optimizing their e-learning investments.
CytoVeris
Venture Round in 2020
CytoVeris is a company that specializes in the development of optical-based technologies aimed at assisting surgical oncologists in the identification and removal of tumor tissue during cancer resection surgeries. Founded in 2018 by Alan Kersey in Farmington, Connecticut, the company focuses on enhancing surgeons' ability to achieve clean margins, which is critical for successful cancer treatment. CytoVeris's innovative devices provide real-time assessments of tissue and generate molecular-specific information, producing an optical biomolecular fingerprint for cancer detection. This advanced technology allows for the detection of molecular signatures created by cancer cells, which can lead to improved patient outcomes and reduced healthcare costs by minimizing the need for repeat surgeries.
Mindnest Health
Seed Round in 2020
MindNest Health, Inc. is a New Haven, Connecticut-based company that develops a digital platform designed to provide parents with access to clinically validated behavioral interventions for their children. Founded in 2016, MindNest Health focuses on addressing various developmental challenges, offering programs specifically for ADHD, autism, and disruptive behaviors, as well as training modules aimed at anxiety and substance abuse. The platform aims to support parents during critical times when they seek assistance for their children's mental health, thereby reducing barriers to care and alleviating parental stress. By providing evidence-based solutions, MindNest Health envisions fostering an environment where children can reach their full potential and families can thrive.
Inbox Health
Venture Round in 2020
Inbox Health Corp. is a digital healthcare company based in New Haven, Connecticut, founded in 2014. It specializes in developing a patient communication platform aimed at medical billers in the United States. The Inbox Health platform automates the patient communication process through bi-directional correspondence and utilizes proprietary algorithms, machine learning, and artificial intelligence. This enables patients to better understand their medical bills and access various payment options. By analyzing a wide range of data points across its customer base, the platform allows billers to personalize the billing, payment, and communication experiences for each patient, ultimately enhancing patient collections and overall satisfaction. The company's mission is to reduce administrative waste in healthcare by streamlining the billing and payment experience for patients.
P2 Science
Series C in 2020
P2 Science, Inc. is a bio-renewable chemistry company based in Woodbridge, Connecticut, that specializes in developing and producing specialty chemicals derived from renewable feedstocks, such as vegetable oils. Founded in 2009 by a team including Yale scientists, P2 Science has created innovative process technologies that transform these sustainable materials into high-value products, including ingredients for flavors, fragrances, and cosmetics, which are traditionally sourced from petrochemicals. The company's offerings cater to various industries, including household and industrial cleaning, personal care, agriculture, environmental remediation, and more. P2 Science aims to support businesses in decarbonizing the chemical industry by providing renewable alternatives to conventional petrochemical ingredients. With a laboratory in New Haven, the company collaborates with major partners across the supply chain to further enhance its technology and market reach.
Enviro Power
Series A in 2020
Enviro Power, LLC is a Connecticut-based company that specializes in developing and marketing innovative heating equipment for both residential and commercial applications. Founded in 2013, the company features its flagship SmartWatt Boiler technology platform, which is designed to generate electricity at near-zero costs while meeting heating demands. This advanced system transforms conventional heating infrastructure into a dual-purpose energy platform, enabling building owners to benefit from reduced utility bills and enhanced grid resiliency. By providing backup power and supporting grid stability, Enviro Power aims to lower carbon footprints and improve energy efficiency for millions of users.
IsoPlexis
Series C in 2020
IsoPlexis is a life science technology company based in Branford, Connecticut, established in 2013. It specializes in developing a single-cell detection system that identifies a wide array of patient immune responses at the single-cell level. The company's platform focuses on cell-based proteomic systems and biomarkers, allowing for the assessment of therapeutic safety and efficacy, monitoring of disease progression, and exploration of functional protein biology and cellular signaling networks. IsoPlexis's technology enables clients to predict cancer patient responses to various novel immunotherapies and cellular therapies, thereby enhancing therapeutic development and informing clinical decision-making.
Wellinks, Inc., established in 2014 and headquartered in New Haven, Connecticut, specializes in wearable health technology for orthotics and prosthetics. The company develops a smart strap for scoliosis braces, tracking wear duration and tightness, and providing real-time data to patients, parents, and doctors. This information enables better-informed treatment decisions, enhances patient motivation, and facilitates remote patient monitoring between clinical visits.
Budderfly
Venture Round in 2019
Budderfly, Inc. is an energy management company that specializes in designing and implementing innovative solutions for optimizing energy consumption. Founded in 2007 and based in Shelton, Connecticut, Budderfly offers a comprehensive range of hardware and software solutions, including a proprietary energy intelligence software platform. This platform enables clients to manage various aspects of energy usage, such as voltage management, energy billing, and peak demand management. Budderfly also integrates a network of IoT devices, LED lighting, HVAC controls, and other energy-efficient technologies to enhance energy efficiency across diverse facilities, including office buildings, schools, and healthcare facilities. By employing an Energy-as-a-Service model, Budderfly provides its services at no upfront cost to clients, resulting in immediate and ongoing energy savings, upgraded infrastructure, and a reduced carbon footprint.
Inbox Health
Seed Round in 2019
Inbox Health Corp. is a digital healthcare company based in New Haven, Connecticut, founded in 2014. It specializes in developing a patient communication platform aimed at medical billers in the United States. The Inbox Health platform automates the patient communication process through bi-directional correspondence and utilizes proprietary algorithms, machine learning, and artificial intelligence. This enables patients to better understand their medical bills and access various payment options. By analyzing a wide range of data points across its customer base, the platform allows billers to personalize the billing, payment, and communication experiences for each patient, ultimately enhancing patient collections and overall satisfaction. The company's mission is to reduce administrative waste in healthcare by streamlining the billing and payment experience for patients.
Cybrexa Therapeutics
Series B in 2019
Cybrexa Therapeutics is a biotechnology company focused on developing an innovative class of small molecule DNA repair inhibitors aimed at improving cancer treatment. Founded in 2016 and based in New Haven, Connecticut, Cybrexa utilizes a proprietary peptide-based technology that specifically targets the tumor microenvironment. This approach allows for enhanced drug delivery and increased therapeutic efficacy, particularly when combined with existing chemotherapies and radiotherapies. By enabling the safe administration of higher drug doses, Cybrexa's therapeutics aim to expand the efficacy of current anticancer agents and address significant unmet medical needs in oncology. The company's novel platform has the potential to redefine drug delivery paradigms and enhance patient outcomes in cancer care.
PayVeris, LLC is a cloud-based digital payment and money transfer platform that provides comprehensive solutions for both consumer and business bill payments, as well as external account-to-account transfers between various financial institutions. Founded in 2011 and headquartered in Cromwell, Connecticut, PayVeris enables person-to-person payments, allowing users to send money electronically from their bank or credit union accounts via web, smartphone, or tablet. The platform includes PayWatch, an integrated fraud prevention solution that monitors transactions for potential risks, and PayItNow, a service that connects financial institutions, merchants, and consumers in the payments process. PayVeris has established strategic partnerships with Kony and Corelation to enhance its offerings and expand its reach in the digital payments landscape.
IsoPlexis
Series C in 2019
IsoPlexis is a life science technology company based in Branford, Connecticut, established in 2013. It specializes in developing a single-cell detection system that identifies a wide array of patient immune responses at the single-cell level. The company's platform focuses on cell-based proteomic systems and biomarkers, allowing for the assessment of therapeutic safety and efficacy, monitoring of disease progression, and exploration of functional protein biology and cellular signaling networks. IsoPlexis's technology enables clients to predict cancer patient responses to various novel immunotherapies and cellular therapies, thereby enhancing therapeutic development and informing clinical decision-making.
Allyx Therapeutics
Convertible Note in 2019
Allyx Therapeutics, Inc. is a clinical-stage biotechnology company founded in 2018 and based in Durham, Connecticut. The company specializes in developing disease-modifying treatments for Alzheimer's Disease, with a focus on reversing neurodegeneration. Its lead product is an orally bioavailable small molecule that functions as a silent allosteric modulator of mGluR5. This innovative approach aims to provide clinicians with a therapeutic option capable of preserving cognition in patients while addressing the underlying disease mechanisms.
Torigen Pharmaceuticals
Series A in 2019
Torigen Pharmaceuticals is a company dedicated to advancing cancer care solutions for companion animals. Founded in 2013 by Ashley Kalinauskas and Mark Suckow, the company is based in Farmington, Connecticut. Torigen focuses on developing innovative immunotherapy treatments, including an experimental autologous cancer vaccine that activates the immune system to target specific tumor-associated antigens on cancer cells. This approach aims to enable veterinarians to detect and treat cancer in animals more effectively, reducing the reliance on invasive surgeries and chemotherapy. By leveraging existing scientific research, Torigen seeks to improve outcomes for pets diagnosed with cancer, enhancing their quality of life through novel therapeutic strategies.
Phlatbed
Venture Round in 2019
Phlatbed Inc. is an on-demand logistics application founded in 2016 and based in Norwalk, Connecticut. The platform connects consumers with local drivers who offer services for moving, packing, loading, and junk removal. Users can place real-time requests and select from multiple drivers based on geographic preferences, service pricing, and availability. Once a driver is accepted, payment is processed automatically through PayPal, credit card, or cash, and both parties can provide feedback on their experience. Phlatbed operates across the United States, Canada, and is expanding into the United Kingdom. The company promotes community engagement through an active blog and social media presence, aiming to eliminate waste and help individuals turn idle assets into revenue.
Bactana Corporation is a research and development company focused on improving microbiome health in livestock and pets through innovative nutritional products. Established in 2016 and based in Farmington, Connecticut, Bactana's proprietary platform, FPS-4, enhances the interaction between an animal's immune system and metabolism to promote productivity and health. The company isolates beneficial molecules from commensal anaerobic bacteria, specifically targeting metabolic conditions and digestive disorders in pets, while also developing sustainable solutions for livestock production that aim to reduce the reliance on antibiotics and minimize natural resource usage. Bactana primarily serves cattle farmers in Connecticut and New York, positioning itself at the forefront of advancements in microbiome technology for both livestock and companion animals.
Source Defense
Series A in 2018
Source Defense Ltd. is a cybersecurity company specializing in website security software that prevents attacks originating from third-party sources. Founded in 2014 and headquartered in Rosh-ha’ayin, Israel, with additional offices in Beer-Sheva and Stamford, Connecticut, the company offers a cloud-based Software-as-a-Service platform. This platform enables site owners to effectively manage their security by setting and enforcing permissions, receiving real-time alerts, and monitoring the activities of third-party vendors on their sites. Source Defense aims to eliminate the security risks associated with third-party integrations, allowing businesses to save significant time and resources while maintaining high performance and safety for site visitors. Its tailored solutions include VICE products designed for various sectors, including financial institutions, insurance companies, e-commerce, and publishing.
Inbox Health
Seed Round in 2018
Inbox Health Corp. is a digital healthcare company based in New Haven, Connecticut, founded in 2014. It specializes in developing a patient communication platform aimed at medical billers in the United States. The Inbox Health platform automates the patient communication process through bi-directional correspondence and utilizes proprietary algorithms, machine learning, and artificial intelligence. This enables patients to better understand their medical bills and access various payment options. By analyzing a wide range of data points across its customer base, the platform allows billers to personalize the billing, payment, and communication experiences for each patient, ultimately enhancing patient collections and overall satisfaction. The company's mission is to reduce administrative waste in healthcare by streamlining the billing and payment experience for patients.
Tunxis Community College
Grant in 2018
In the Farmington, Connecticut area, Tunxis Community College has academic, workforce training, and personal enrichment courses for students with all sorts of different interests that can earn you an associate’s degree or certificate. Among the many majors to choose from are programs such as Allied Health, Graphic Design, Visual Fine Arts, Business Office Technology, Computer Information Systems, Criminal Justice, Drug and Alcohol Recovery Counselor, Early Childhood Education, Engineering Science and Technology Studies, and New Media Communication, as well as many more. Counselors in the financial aid office can point you toward programs that will help you earn loans, grants, scholarships, veteran’s benefits, and more if you qualify. These financial aid options can help you pay for tuition and other expenses. Student life at TCC includes a student lounge, The Cyber Café, and the Barnes-Franklin Gallery, which is filled with student, community, and professional art. Academic advising is available for any student who needs help. The career center can help students find employment. Other student resources includes child care, health care, media center, and student activities.
Phlatbed
Venture Round in 2018
Phlatbed Inc. is an on-demand logistics application founded in 2016 and based in Norwalk, Connecticut. The platform connects consumers with local drivers who offer services for moving, packing, loading, and junk removal. Users can place real-time requests and select from multiple drivers based on geographic preferences, service pricing, and availability. Once a driver is accepted, payment is processed automatically through PayPal, credit card, or cash, and both parties can provide feedback on their experience. Phlatbed operates across the United States, Canada, and is expanding into the United Kingdom. The company promotes community engagement through an active blog and social media presence, aiming to eliminate waste and help individuals turn idle assets into revenue.
ReNetX Bio
Series A in 2018
ReNetX Bio, Inc. is a biotechnology company focused on developing and marketing therapeutics aimed at treating injuries and damage to the central nervous system (CNS). The company provides Nogo Trap, a decoy receptor that binds growth inhibitors to facilitate natural nerve fiber growth, promoting axonal regeneration, sprouting, and synaptic plasticity. ReNetX Bio's therapeutic offerings address conditions such as spinal cord injury, stroke, and glaucoma. The company, originally founded as Axerion Therapeutics in 2009, rebranded to ReNetX Bio in July 2017 and is headquartered in New Haven, Connecticut. Its innovative approach includes the development of small molecule oral compounds designed to block harmful protein interactions in the brain, thereby supporting recovery in patients with various CNS disorders.
OncoSynergy
Series A in 2018
OncoSynergy is a biotechnology company founded in 2011 and headquartered in Greenwich, Connecticut. As a spin-out from the University of California, San Francisco, the company focuses on developing innovative immunotherapies aimed at improving outcomes for cancer patients with unmet medical needs. OncoSynergy's approach centers on Resistance Mechanism Inhibitors (RMIs), a novel class of therapeutics that targets multiple pathways involved in cancer progression. These therapies have shown significant preclinical efficacy both as standalone treatments and in combination with other therapies. By employing this transformative strategy, OncoSynergy seeks to provide oncologists with options that can lead to durable outcomes and potential cures for patients battling cancer.
Rallybio, LLC is a clinical-stage biopharmaceutical company based in New Haven, Connecticut, focused on developing innovative therapies for patients with severe and rare disorders. Founded in 2018, Rallybio is dedicated to addressing critical medical needs, particularly in the fields of hematology, immuno-inflammation, maternal-fetal health, and metabolic disorders. Its lead product candidate, RLYB211, is designed for the prevention of fetal and neonatal alloimmune thrombocytopenia (FNAIT), a serious condition that can lead to uncontrolled bleeding in fetuses and newborns. The company emphasizes the use of antibodies, small molecules, and engineered proteins in its drug development efforts. Rallybio is supported by a team of experienced professionals with extensive expertise in biopharmaceutical research and development, particularly in the realm of rare diseases.
GoNation
Venture Round in 2018
GoNation LLC is a mobile platform focused on enhancing the online presence of small businesses across several states, including Connecticut, Massachusetts, Louisiana, California, and New York. Established in 2011 and headquartered in Milford, Connecticut, the company offers users personalized profiles that facilitate connections with local businesses and fellow users. By leveraging innovative technology and data-driven tools, GoNation aims to simplify online operations for small businesses, helping them to maximize revenue and engage effectively with customers. The platform integrates elements of social media and shareable data, creating a comprehensive local discovery tool that transforms how individuals explore their communities and supports the growth of local enterprises both online and offline.
FallCall Solutions
Seed Round in 2018
FallCall Solutions, LLC is a company based in Trumbull, Connecticut, specializing in fall detection applications tailored for the geriatric population and their caregivers. Founded in 2015, the company has developed a telemonitoring platform that enhances communication and safety for elderly individuals. Its flagship product, FallCall Now, is capable of distinguishing between low and high mechanism falls and can notify both family members and central dispatch agencies in the event of a fall. Additionally, FallCall Solutions offers ElderCheck Now, which facilitates ongoing communication between seniors and their caregivers. The company focuses on leveraging widely adopted mobile technologies to create user-friendly applications that empower elders to maintain their independence while providing peace of mind for caregivers.
Biorez, Inc. is a medical device company focused on developing bioresorbable scaffold implants aimed at enhancing tissue regeneration in vivo. Founded in 2008 and based in New Haven, Connecticut, the company offers innovative products such as the L-C Ligament, designed for anterior cruciate ligament (ACL) reconstruction, which eliminates the need for donor tissue harvesting and serves as a superior alternative to cadaver-based materials. Biorez utilizes patented technology involving a degradable polymer, PLLA, in its orthopedic implants to promote the regeneration and augmentation of soft tissue. Among its offerings is the biorez GRAFT, a FDA-cleared device for soft tissue augmentation of the rotator cuff. The company’s bioinductive implants stabilize surgical repairs while the body rebuilds its musculoskeletal tissue, thereby facilitating quicker and safer recovery for patients and providing surgeons with effective tools to improve soft tissue repair outcomes.
GoNation
Funding Round in 2017
GoNation LLC is a mobile platform focused on enhancing the online presence of small businesses across several states, including Connecticut, Massachusetts, Louisiana, California, and New York. Established in 2011 and headquartered in Milford, Connecticut, the company offers users personalized profiles that facilitate connections with local businesses and fellow users. By leveraging innovative technology and data-driven tools, GoNation aims to simplify online operations for small businesses, helping them to maximize revenue and engage effectively with customers. The platform integrates elements of social media and shareable data, creating a comprehensive local discovery tool that transforms how individuals explore their communities and supports the growth of local enterprises both online and offline.
LambdaVision
Series A in 2017
LambdaVision, Incorporated is focused on developing a protein-based artificial retina aimed at restoring vision for individuals affected by advanced retinal degenerative diseases, such as retinitis pigmentosa and age-related macular degeneration. Founded in 2009 and based in Farmington, Connecticut, the company is commercializing a retinal implant that leverages light-activated proteins, specifically bacteriorhodopsin, to stimulate the retinas of patients with significant vision impairment. By providing innovative solutions for those suffering from these debilitating conditions, LambdaVision seeks to enhance the quality of life for millions of patients facing vision loss.
Wellinks
Venture Round in 2017
Wellinks, Inc., established in 2014 and headquartered in New Haven, Connecticut, specializes in wearable health technology for orthotics and prosthetics. The company develops a smart strap for scoliosis braces, tracking wear duration and tightness, and providing real-time data to patients, parents, and doctors. This information enables better-informed treatment decisions, enhances patient motivation, and facilitates remote patient monitoring between clinical visits.
Edge2Web
Convertible Note in 2017
Edge2Web, Inc. is a technology company specializing in cloud-based visual tools that facilitate the rapid development, assembly, and deployment of industrial Internet of Things (IIoT) applications. Founded in 2016 and headquartered in Woodbury, Connecticut, Edge2Web provides a low-code platform that empowers industrial professionals to create sophisticated dashboards and interactive applications, such as machine monitors and manufacturing process visualizations. Its flagship product, Edge2Web Director, enables users to integrate data across various operational and enterprise environments, allowing for enhanced insights and improved decision-making. The company's SaaS solutions are designed to accelerate the implementation and scaling of operational efficiency applications, ensuring minimal disruption to existing IT systems while addressing a wide range of industrial use cases.
IsoPlexis
Series B in 2017
IsoPlexis is a life science technology company based in Branford, Connecticut, established in 2013. It specializes in developing a single-cell detection system that identifies a wide array of patient immune responses at the single-cell level. The company's platform focuses on cell-based proteomic systems and biomarkers, allowing for the assessment of therapeutic safety and efficacy, monitoring of disease progression, and exploration of functional protein biology and cellular signaling networks. IsoPlexis's technology enables clients to predict cancer patient responses to various novel immunotherapies and cellular therapies, thereby enhancing therapeutic development and informing clinical decision-making.
The Big Willow
Convertible Note in 2017
The Big Willow, Inc. is a technology company that specializes in designing and developing marketing platforms aimed at enhancing buyer engagement and intent identification. Founded in 2013 and headquartered in Wilton, Connecticut, the company leverages advanced analytics to index content consumption across web sessions, linking off-site behavior to activity data from various marketing and sales tools. Its product offerings include a B2B-centric programmatic advertising platform designed around buyer intent, account-based marketing solutions, and pre-targeted advertising and custom content syndication services. The Big Willow also provides marketing technology solutions that drive account-based marketing initiatives and sales enablement solutions to expedite deal flow and increase revenue from qualified leads. By processing vast amounts of web data, the company helps clients uncover buying intent and optimize their marketing strategies to improve engagement with potential customers.
Cybrexa Therapeutics
Series B in 2017
Cybrexa Therapeutics is a biotechnology company focused on developing an innovative class of small molecule DNA repair inhibitors aimed at improving cancer treatment. Founded in 2016 and based in New Haven, Connecticut, Cybrexa utilizes a proprietary peptide-based technology that specifically targets the tumor microenvironment. This approach allows for enhanced drug delivery and increased therapeutic efficacy, particularly when combined with existing chemotherapies and radiotherapies. By enabling the safe administration of higher drug doses, Cybrexa's therapeutics aim to expand the efficacy of current anticancer agents and address significant unmet medical needs in oncology. The company's novel platform has the potential to redefine drug delivery paradigms and enhance patient outcomes in cancer care.
Trinity Mobile Networks
Venture Round in 2017
Trinity Mobile Networks, Inc. is a technology company based in New Haven, Connecticut, specializing in the development of a software-defined networking (SDN) platform tailored for smartphones and other mobile devices. The company's flagship product, TrinitySDN, facilitates the integration of cellular, Wi-Fi, and mesh connections, enabling enhanced data speed and network bandwidth. By utilizing its innovative platform, network operators can manage and monitor diverse network types, optimize traffic, and implement seamless handoffs between different connections. Trinity Mobile Networks also focuses on improving the performance of wireless mesh networks, providing users with affordable connectivity and reducing dependence on costly cellular services. The company’s solutions include real-time diagnostics, secure virtual sub-networks, and enhanced quality of service, all designed to operate efficiently within the constraints of mobile devices. Established in 2014, Trinity Mobile Networks aims to revolutionize the way mobile connectivity is experienced by leveraging advanced networking technologies.
Bactana
Seed Round in 2017
Bactana Corporation is a research and development company focused on improving microbiome health in livestock and pets through innovative nutritional products. Established in 2016 and based in Farmington, Connecticut, Bactana's proprietary platform, FPS-4, enhances the interaction between an animal's immune system and metabolism to promote productivity and health. The company isolates beneficial molecules from commensal anaerobic bacteria, specifically targeting metabolic conditions and digestive disorders in pets, while also developing sustainable solutions for livestock production that aim to reduce the reliance on antibiotics and minimize natural resource usage. Bactana primarily serves cattle farmers in Connecticut and New York, positioning itself at the forefront of advancements in microbiome technology for both livestock and companion animals.
Inbox Health
Seed Round in 2017
Inbox Health Corp. is a digital healthcare company based in New Haven, Connecticut, founded in 2014. It specializes in developing a patient communication platform aimed at medical billers in the United States. The Inbox Health platform automates the patient communication process through bi-directional correspondence and utilizes proprietary algorithms, machine learning, and artificial intelligence. This enables patients to better understand their medical bills and access various payment options. By analyzing a wide range of data points across its customer base, the platform allows billers to personalize the billing, payment, and communication experiences for each patient, ultimately enhancing patient collections and overall satisfaction. The company's mission is to reduce administrative waste in healthcare by streamlining the billing and payment experience for patients.
SmartPay Solutions
Series A in 2016
SmartPay Solutions LLC, established in 2010 and headquartered in Southington, Connecticut, specializes in providing software solutions for pay-as-you-go workers' compensation plans. The company offers its SmartPay solution to insurance agents, insurance carriers, and payroll providers, facilitating a streamlined and efficient approach to managing workers' compensation insurance. By leveraging cloud-based technology, SmartPay Solutions enables its clients to access a virtual software platform that is designed to be user-friendly and adaptable to various needs. The company's innovative offerings enhance the experience for all stakeholders involved in the workers' compensation process.
Cadenza Innovation
Series A in 2016
Cadenza Innovation, Inc. is a manufacturer of lithium-ion batteries, primarily serving the electric vehicle market. Founded in 2012 and based in Wilton, Connecticut, the company specializes in patented battery design and architecture that combines the advantages of traditional jelly roll and large prismatic cell structures. This innovative design enables high energy density at a lower cost, making it suitable for various applications. Cadenza Innovation focuses on developing safe, reliable, and high-performance energy storage solutions, which are utilized in hybrid, off-grid, and grid-connected telecom sites. The company's offerings emphasize long cycle life, optional high-temperature performance configurations, and real-time monitoring capabilities, enhancing performance and safety for clients in the global energy sector.
PayVeris
Venture Round in 2016
PayVeris, LLC is a cloud-based digital payment and money transfer platform that provides comprehensive solutions for both consumer and business bill payments, as well as external account-to-account transfers between various financial institutions. Founded in 2011 and headquartered in Cromwell, Connecticut, PayVeris enables person-to-person payments, allowing users to send money electronically from their bank or credit union accounts via web, smartphone, or tablet. The platform includes PayWatch, an integrated fraud prevention solution that monitors transactions for potential risks, and PayItNow, a service that connects financial institutions, merchants, and consumers in the payments process. PayVeris has established strategic partnerships with Kony and Corelation to enhance its offerings and expand its reach in the digital payments landscape.
Wellinks
Venture Round in 2016
Wellinks, Inc., established in 2014 and headquartered in New Haven, Connecticut, specializes in wearable health technology for orthotics and prosthetics. The company develops a smart strap for scoliosis braces, tracking wear duration and tightness, and providing real-time data to patients, parents, and doctors. This information enables better-informed treatment decisions, enhances patient motivation, and facilitates remote patient monitoring between clinical visits.
ShopLandia
Convertible Note in 2015
Shoplandia, Inc. is a mobile application developer based in Stamford, Connecticut, established in 2014. The company offers a unique shoppable video platform that allows users to create, edit, and stream product videos for online sales. This end-to-end software as a service (SaaS) solution enables peer-to-peer selling through both recorded and live video formats. Users can customize their videos with various features, including music, filters, and special effects, facilitating a dynamic and engaging shopping experience. Shoplandia's innovative approach aims to streamline the process of showcasing products, making it easier for sellers to connect with potential buyers.
Arccos Golf
Venture Round in 2015
Arccos Golf, LLC, incorporated in 2012 and based in Stamford, Connecticut, specializes in developing and marketing sensor-based technology and mobile applications for real-time performance tracking in golf. The company offers the Arccos Caddie platform, which features automatic shot tracking, smart distance club averages, an A.I.-powered GPS rangefinder, and advanced analytics to assist golfers of all skill levels. By utilizing sensors that attach to golf clubs, Arccos Golf enables users to track critical metrics such as clubhead speed and face angle, uploading this data to a mobile application for analysis. The insights provided by Arccos Golf's products aim to help golfers make informed decisions, enhance their skills, and ultimately improve their game.
Chiefofstaff.com
Convertible Note in 2015
Chiefofstaff.com LLC is a cloud-based strategic plan management platform headquartered in Hartford, Connecticut, with additional offices in major cities including New York, Boston, and Chicago, as well as international locations in Brussels and Oslo. The company provides a collaborative strategy execution software designed to facilitate the implementation and monitoring of strategic plans within organizations. Its platform enables executives to measure and manage the execution of strategies in real-time, allowing for immediate feedback and actionable insights. This functionality empowers CEOs to focus on critical issues while maintaining visibility into every aspect of their organization's plans. Chiefofstaff.com is tailored to meet the needs of complex organizations, offering a customizable and scalable solution that integrates multiple strategic plans into a single, transparent view. The platform has been utilized by various clients, including New York Life Mexico and Deloitte, and was founded by Robert Epner, a seasoned Chief-of-Staff.
SeeClickFix
Venture Round in 2015
SeeClickFix, Inc. is a communications platform that enables citizens to report non-emergency issues while providing governments with tools to track, manage, and respond to these reports. Founded in 2007 and based in New Haven, Connecticut, the company aims to enhance community engagement through transparency and collaboration. Its offerings include Request Management for data collection and citizen communication, Work Management for internal communications, and Citizen Engagement tools that facilitate interaction between local communities and their governments. Additionally, SeeClickFix provides data analytics to assess public service effectiveness and inform decision-making. The platform also features mobile applications and backend tools designed to streamline communication between citizens and city officials, thereby fostering a more responsive and accountable local government.
NorthPage
Venture Round in 2015
NorthPage Inc. is a technology company that offers a cloud-based digital marketing optimization platform designed to enhance the performance of enterprise marketing organizations. Founded in 2007 and headquartered in Southbury, Connecticut, NorthPage provides tools for frictionless performance benchmarking, competitive analysis, and best-practice guidance. Its platform leverages cognitive marketing analytics and algorithmic approaches to analyze and optimize various digital marketing programs, including websites, e-commerce sites, mobile marketing, social media, search engine marketing, content marketing, and e-retail initiatives. The company caters to a diverse range of sectors, including retail, financial services, consumer products, pharmaceuticals, and technology, enabling marketers to gain data-driven insights and actionable recommendations to improve customer journeys, user experiences, and overall engagement.
Cafe Learn
Seed Round in 2015
Cafe Learn LLC is a cloud-based Software-as-a-Service platform based in Stamford, Connecticut, that enhances educational experiences for school students. Incorporated in 2015, the company enables instructors to create, share, and customize blended, social, and personalized courses, offering complete content flexibility. By focusing on student success, Cafe Learn provides educators with real-time data that tracks student mastery of measurable outcomes, thereby facilitating improved engagement and learning strategies. As a subsidiary of O'Donnell Group LLC, Cafe Learn aims to evolve teaching and learning methodologies within educational institutions.
Device42
Seed Round in 2015
Device42, Inc. is a software company that specializes in providing solutions for system, network, and data center engineers, as well as IT managers. Founded in 2010 and headquartered in West Haven, Connecticut, with an additional office in Boston, Massachusetts, Device42 offers a comprehensive suite of tools designed for IT inventory management, patch panel cable management, data center power management, and IP address tracking. Its platform includes essential features such as Configuration Management Database (CMDB), Application Dependency Mapping (ADM), and a DCIM Software Marketplace, all aimed at helping organizations maintain accurate inventories of both IP-based and non-IP assets. The software facilitates various IT operations, compliance auditing, migration, and modernization processes, making it easier for clients to manage hybrid IT environments and execute successful cloud migrations while ensuring compliance with internal and external regulations.
eBrevia
Seed Round in 2014
eBrevia Inc., established in 2011, specializes in developing artificial intelligence-driven software for legal professionals. Its primary products include Diligence Accelerator for streamlined due diligence processes, Contract Analyzer for efficient contract management, Lease Abstractor to simplify lease reviews, and Bespoke for custom term identification. These tools enable law firms and corporate legal departments to enhance accuracy, reduce time and costs associated with document review, and improve overall workflow efficiency. Headquartered in Stamford, Connecticut, with additional offices in San Francisco and New York, eBrevia operates as a subsidiary of Donnelley Financial Solutions Inc., following its acquisition in 2018. The company's innovative technology has been recognized through various awards, including the Startup America DEMO Competition and the Connecticut Technology Council's Most Promising Software Product of the Year award.
Fitscript
Seed Round in 2014
Fitscript LLC is a company that specializes in digital exercise programs aimed at diabetes prevention and weight management. The company's flagship application, GlucoseZone, offers a variety of exercise videos tailored to different needs, including total body workouts, chair exercises, core and abdominal routines, yoga, and strength training. Fitscript provides users with personalized exercise guidance based on their real-time glucose levels, diabetes conditions, and fitness goals, making it particularly beneficial for individuals with type 1 and type 2 diabetes. Type 1 users receive strategies to manage glucose fluctuations, while type 2 users are offered programs focused on weight loss. Originally founded as Exerscrip LLC in 2010, the company rebranded to Fitscript in April 2016 and is headquartered in New Haven, Connecticut.
Wellinks
Seed Round in 2014
Wellinks, Inc., established in 2014 and headquartered in New Haven, Connecticut, specializes in wearable health technology for orthotics and prosthetics. The company develops a smart strap for scoliosis braces, tracking wear duration and tightness, and providing real-time data to patients, parents, and doctors. This information enables better-informed treatment decisions, enhances patient motivation, and facilitates remote patient monitoring between clinical visits.
GestVision
Seed Round in 2014
GestVision, Inc. is a medical diagnostics company based in Groton, Connecticut, focused on developing innovative solutions for the detection of preeclampsia in pregnant women. Established in 2014, the company has commercialized a point-of-care diagnostic test known as the Congo Red Dot urine test, which is designed to confirm or rule out preeclampsia. This pregnancy-related condition, characterized by high blood pressure and protein in the urine, poses significant health risks, including seizures and mortality if left untreated. GestVision aims to improve maternal and fetal health by providing effective diagnostic tools that enhance the detection and management of preeclampsia, addressing a growing concern in both developed and developing countries.
ZetrOZ, LLC is a manufacturer based in Trumbull, Connecticut, specializing in advanced ultrasound technology. Founded in 2009, the company focuses on developing non-invasive medical devices aimed at tissue healing and pain relief for chronic musculoskeletal conditions. ZetrOZ offers a range of products, including the UltrOZ Elite therapeutic systems, wearable veterinary ultrasound systems, and high intensity focused ultrasound systems tailored for biomedical research and industrial applications. Their product lineup also features low-profile ultrasound transducers for therapeutic and diagnostic uses, as well as a variety of applications in industrial monitoring and aquatic environments. The company's innovative generator technology enhances efficiency, portability, and cost-effectiveness, making ultrasound systems more accessible for therapeutic uses such as wound care, surgical procedures, and aesthetic treatments.
IsoPlexis
Series A in 2014
IsoPlexis is a life science technology company based in Branford, Connecticut, established in 2013. It specializes in developing a single-cell detection system that identifies a wide array of patient immune responses at the single-cell level. The company's platform focuses on cell-based proteomic systems and biomarkers, allowing for the assessment of therapeutic safety and efficacy, monitoring of disease progression, and exploration of functional protein biology and cellular signaling networks. IsoPlexis's technology enables clients to predict cancer patient responses to various novel immunotherapies and cellular therapies, thereby enhancing therapeutic development and informing clinical decision-making.
SmartPay Solutions
Series A in 2014
SmartPay Solutions LLC, established in 2010 and headquartered in Southington, Connecticut, specializes in providing software solutions for pay-as-you-go workers' compensation plans. The company offers its SmartPay solution to insurance agents, insurance carriers, and payroll providers, facilitating a streamlined and efficient approach to managing workers' compensation insurance. By leveraging cloud-based technology, SmartPay Solutions enables its clients to access a virtual software platform that is designed to be user-friendly and adaptable to various needs. The company's innovative offerings enhance the experience for all stakeholders involved in the workers' compensation process.
P2 Science
Series A in 2014
P2 Science, Inc. is a bio-renewable chemistry company based in Woodbridge, Connecticut, that specializes in developing and producing specialty chemicals derived from renewable feedstocks, such as vegetable oils. Founded in 2009 by a team including Yale scientists, P2 Science has created innovative process technologies that transform these sustainable materials into high-value products, including ingredients for flavors, fragrances, and cosmetics, which are traditionally sourced from petrochemicals. The company's offerings cater to various industries, including household and industrial cleaning, personal care, agriculture, environmental remediation, and more. P2 Science aims to support businesses in decarbonizing the chemical industry by providing renewable alternatives to conventional petrochemical ingredients. With a laboratory in New Haven, the company collaborates with major partners across the supply chain to further enhance its technology and market reach.
Avitus Orthopaedics
Seed Round in 2014
Avitus Orthopaedics, Inc. is a medical device company dedicated to developing and commercializing minimally invasive orthopedic surgical devices, specifically focusing on autologous bone graft harvesting. Founded in 2011 and headquartered in Shelton, Connecticut, the company offers innovative instruments, including the Avitus bone harvester, which is designed to efficiently harvest cancellous bone and marrow. Avitus Orthopaedics aims to enhance clinical outcomes and reduce healthcare costs through its advanced surgical technologies, contributing to improved patient care in reconstructive orthopedic surgeries. The company, formerly known as BOSS Medical, Inc., changed its name in March 2014 to reflect its commitment to orthopedic solutions.
CashPath Financial
Seed Round in 2014
CashPath Financial LLC is a financial technology company based in Stamford, Connecticut, established in 2011. The company specializes in cash-flow management services, utilizing innovative technology to help individuals achieve everyday financial success. CashPath has developed a mobile application that predicts future cash flow, enabling users to understand how much they can spend on a daily, weekly, and monthly basis. By providing insights into spending and saving, the app aims to guide users towards positive cash flow, enhanced savings, and improved financial well-being. The company is currently preparing to launch a beta version of its mobile application, which will further facilitate users in planning for their financial growth.
GlyGenix Therapeutics
Seed Round in 2014
GlyGenix Therapeutics, Inc. is a biotechnology company focused on developing therapeutic products aimed at treating metabolic disorders. Specifically, the company works on manufacturing and delivering gene therapies to address Glycogen Storage Disease Type 1a (GSD1a). Founded in 2006 and headquartered in Woodbridge, Connecticut, GlyGenix Therapeutics collaborates with prominent institutions, including the National Institutes of Health, Duke University, the University of Florida, and Royal Philips Electronics, to advance its innovative approaches in gene therapy.
Eli Nutrition
Seed Round in 2014
Eli Nutrition, Inc. is a company specializing in the development of antacid products. Founded in 2013 and based in New Haven, Connecticut, the company offers Tummyzen, a zinc-based over-the-counter antacid pill designed to provide relief from heartburn.
BioRez
Venture Round in 2014
Biorez, Inc. is a medical device company focused on developing bioresorbable scaffold implants aimed at enhancing tissue regeneration in vivo. Founded in 2008 and based in New Haven, Connecticut, the company offers innovative products such as the L-C Ligament, designed for anterior cruciate ligament (ACL) reconstruction, which eliminates the need for donor tissue harvesting and serves as a superior alternative to cadaver-based materials. Biorez utilizes patented technology involving a degradable polymer, PLLA, in its orthopedic implants to promote the regeneration and augmentation of soft tissue. Among its offerings is the biorez GRAFT, a FDA-cleared device for soft tissue augmentation of the rotator cuff. The company’s bioinductive implants stabilize surgical repairs while the body rebuilds its musculoskeletal tissue, thereby facilitating quicker and safer recovery for patients and providing surgeons with effective tools to improve soft tissue repair outcomes.
CashPath Financial
Venture Round in 2013
CashPath Financial LLC is a financial technology company based in Stamford, Connecticut, established in 2011. The company specializes in cash-flow management services, utilizing innovative technology to help individuals achieve everyday financial success. CashPath has developed a mobile application that predicts future cash flow, enabling users to understand how much they can spend on a daily, weekly, and monthly basis. By providing insights into spending and saving, the app aims to guide users towards positive cash flow, enhanced savings, and improved financial well-being. The company is currently preparing to launch a beta version of its mobile application, which will further facilitate users in planning for their financial growth.
Precipio Diagnostics
Series B in 2013
Precipio Diagnostics is a cancer diagnostics company based in New Haven, Connecticut, specializing in clinical diagnostic services for hematopoietic cancers. The company offers advanced diagnostic products, including the HemeScreen panel for genetic mutation testing and the IV-Cell media, which enhances the accuracy of laboratory results. Precipio serves a diverse clientele, including oncologists, hospitals, reference laboratories, and pharmaceutical companies. In its commitment to improving cancer care, the company collaborates with prominent academic institutions such as the Yale School of Medicine and Dana-Farber Cancer Institute, fostering connections between physicians and leading pathologists. With laboratories in New Haven and Omaha, Precipio aims to reduce instances of cancer misdiagnoses and provide essential diagnostics to oncologists across the United States.
AxioMx
Venture Round in 2013
AxioMx Inc., founded in 2012 and based in Branford, Connecticut, specializes in the discovery, development, production, and delivery of recombinant antibodies. The company provides a comprehensive suite of custom antibody services, catering to the needs of life science researchers across diagnostic, pharmaceutical, biotechnology, and academic sectors. AxioMx's offerings include antigen and project design consultation, recombinant antibody development, antibody optimization, and protein production and purification services. Utilizing proprietary phage display libraries and affinity maturation techniques, the company excels in creating high-affinity, specific antibodies, including those for challenging targets such as phosphorylated proteins and non-immunogenic antigens. Additionally, AxioMx supports various antibody optimization processes, including scFv to IgG conversion and antibody labeling. The company is recognized for its innovative approach to synthetic recombinant antibodies, which serve vital roles in research, diagnostic tests, and therapeutic applications.
Arvinas, Inc. is a clinical-stage biopharmaceutical company based in New Haven, Connecticut, that specializes in the discovery, development, and commercialization of innovative therapies aimed at degrading disease-causing proteins. The company's lead product candidates include ARV-110, a proteolysis targeting chimera (PROTAC) currently in phase I clinical trials for metastatic castration-resistant prostate cancer, and ARV-471, which targets the estrogen receptor for patients with metastatic ER-positive/HER2-negative breast cancer. In addition to these, Arvinas is developing various other PROTACs aimed at degrading clinically relevant androgen receptor mutations and treatments for neurodegenerative diseases, including tauopathies. The company has established collaborations with prominent pharmaceutical firms such as Pfizer Inc., Genentech, and Bayer AG, enhancing its research capabilities and reach within the biopharmaceutical landscape. Founded in 2015, Arvinas aims to improve patient outcomes by eliminating harmful proteins from the body through its proprietary technology.
American Oil Solutions
Seed Round in 2013
American Oil Solutions (AOS) is a green technology company based in Bridgeport, Connecticut, specializing in the recycling of used hydrocarbon products, particularly tires. The company employs a closed-loop, pollution-free process that transforms old tires into various valuable resources, including fuel oil, carbon products, syngas, scrap steel, and specialty chemicals. AOS aims to establish itself as a leader in the market for hydrocarbon product recycling by utilizing the readily available supply of tires, which allows for multiple product lines and revenue streams. Through its innovative technology, AOS contributes to environmental sustainability while addressing the challenges of waste management in the hydrocarbon sector.
iCleanse
Seed Round in 2013
iCleanse is a privately held company that specializes in the development of multi-bay docking stations designed for the secure storage, charging, and disinfection of mobile devices such as tablets and smartphones. Established in 2012 and headquartered in Avon, Connecticut, iCleanse is recognized for being the first provider of a chemical-free disinfection solution for mobile devices. Its products are widely utilized across various sectors, including healthcare, retail, and food service, where the safe management of devices is crucial. By effectively eliminating pathogens that could cause infections, iCleanse aims to enhance safety and promote a healthier environment in workplaces and public spaces. The company markets its innovative solutions through a network of resellers.
Logicbroker
Series A in 2013
Logicbroker, Inc. is a technology company specializing in cloud and supply chain automation solutions tailored for digital commerce. Founded in 2010 and headquartered in Shelton, Connecticut, Logicbroker provides advanced electronic data interchange (EDI) and drop ship technology that integrates brands, retailers, and their operational systems. The company's offerings include a comprehensive suite of tools for monitoring supply chain data, such as inventory management, acknowledgments, shipments, and invoices, alongside a robust Logicbroker Commerce API that streamlines communication between partners throughout the order lifecycle. With a network of over 4,000 brand suppliers and more than 140 certified retail and marketplace channels, Logicbroker facilitates significant online sales growth, driving over $2.2 billion annually for leading retailers. Its notable clients include well-known brands such as Kroger, Coca-Cola, and Unilever, and the company maintains a strategic partnership with Ingram Micro Commerce & Lifecycle Services to enhance its service offerings.
P2 Science
Seed Round in 2013
P2 Science, Inc. is a bio-renewable chemistry company based in Woodbridge, Connecticut, that specializes in developing and producing specialty chemicals derived from renewable feedstocks, such as vegetable oils. Founded in 2009 by a team including Yale scientists, P2 Science has created innovative process technologies that transform these sustainable materials into high-value products, including ingredients for flavors, fragrances, and cosmetics, which are traditionally sourced from petrochemicals. The company's offerings cater to various industries, including household and industrial cleaning, personal care, agriculture, environmental remediation, and more. P2 Science aims to support businesses in decarbonizing the chemical industry by providing renewable alternatives to conventional petrochemical ingredients. With a laboratory in New Haven, the company collaborates with major partners across the supply chain to further enhance its technology and market reach.
eBrevia
Seed Round in 2013
eBrevia Inc., established in 2011, specializes in developing artificial intelligence-driven software for legal professionals. Its primary products include Diligence Accelerator for streamlined due diligence processes, Contract Analyzer for efficient contract management, Lease Abstractor to simplify lease reviews, and Bespoke for custom term identification. These tools enable law firms and corporate legal departments to enhance accuracy, reduce time and costs associated with document review, and improve overall workflow efficiency. Headquartered in Stamford, Connecticut, with additional offices in San Francisco and New York, eBrevia operates as a subsidiary of Donnelley Financial Solutions Inc., following its acquisition in 2018. The company's innovative technology has been recognized through various awards, including the Startup America DEMO Competition and the Connecticut Technology Council's Most Promising Software Product of the Year award.
Innovatient Solutions
Series A in 2013
Innovatient Solutions provides a patient engagement solution to the health care industry. They strive every day to enable patients to take more control of their health and to have more say in how they are cared for before, during, and after their hospital stay. It was founded in 2010 and headquartered in Farmington, Connecticut.
ZetrOZ, LLC is a manufacturer based in Trumbull, Connecticut, specializing in advanced ultrasound technology. Founded in 2009, the company focuses on developing non-invasive medical devices aimed at tissue healing and pain relief for chronic musculoskeletal conditions. ZetrOZ offers a range of products, including the UltrOZ Elite therapeutic systems, wearable veterinary ultrasound systems, and high intensity focused ultrasound systems tailored for biomedical research and industrial applications. Their product lineup also features low-profile ultrasound transducers for therapeutic and diagnostic uses, as well as a variety of applications in industrial monitoring and aquatic environments. The company's innovative generator technology enhances efficiency, portability, and cost-effectiveness, making ultrasound systems more accessible for therapeutic uses such as wound care, surgical procedures, and aesthetic treatments.
iCleanse
Seed Round in 2013
iCleanse is a privately held company that specializes in the development of multi-bay docking stations designed for the secure storage, charging, and disinfection of mobile devices such as tablets and smartphones. Established in 2012 and headquartered in Avon, Connecticut, iCleanse is recognized for being the first provider of a chemical-free disinfection solution for mobile devices. Its products are widely utilized across various sectors, including healthcare, retail, and food service, where the safe management of devices is crucial. By effectively eliminating pathogens that could cause infections, iCleanse aims to enhance safety and promote a healthier environment in workplaces and public spaces. The company markets its innovative solutions through a network of resellers.
P2 Science
Seed Round in 2013
P2 Science, Inc. is a bio-renewable chemistry company based in Woodbridge, Connecticut, that specializes in developing and producing specialty chemicals derived from renewable feedstocks, such as vegetable oils. Founded in 2009 by a team including Yale scientists, P2 Science has created innovative process technologies that transform these sustainable materials into high-value products, including ingredients for flavors, fragrances, and cosmetics, which are traditionally sourced from petrochemicals. The company's offerings cater to various industries, including household and industrial cleaning, personal care, agriculture, environmental remediation, and more. P2 Science aims to support businesses in decarbonizing the chemical industry by providing renewable alternatives to conventional petrochemical ingredients. With a laboratory in New Haven, the company collaborates with major partners across the supply chain to further enhance its technology and market reach.
NorthPage
Venture Round in 2013
NorthPage Inc. is a technology company that offers a cloud-based digital marketing optimization platform designed to enhance the performance of enterprise marketing organizations. Founded in 2007 and headquartered in Southbury, Connecticut, NorthPage provides tools for frictionless performance benchmarking, competitive analysis, and best-practice guidance. Its platform leverages cognitive marketing analytics and algorithmic approaches to analyze and optimize various digital marketing programs, including websites, e-commerce sites, mobile marketing, social media, search engine marketing, content marketing, and e-retail initiatives. The company caters to a diverse range of sectors, including retail, financial services, consumer products, pharmaceuticals, and technology, enabling marketers to gain data-driven insights and actionable recommendations to improve customer journeys, user experiences, and overall engagement.
eBrevia
Seed Round in 2013
eBrevia Inc., established in 2011, specializes in developing artificial intelligence-driven software for legal professionals. Its primary products include Diligence Accelerator for streamlined due diligence processes, Contract Analyzer for efficient contract management, Lease Abstractor to simplify lease reviews, and Bespoke for custom term identification. These tools enable law firms and corporate legal departments to enhance accuracy, reduce time and costs associated with document review, and improve overall workflow efficiency. Headquartered in Stamford, Connecticut, with additional offices in San Francisco and New York, eBrevia operates as a subsidiary of Donnelley Financial Solutions Inc., following its acquisition in 2018. The company's innovative technology has been recognized through various awards, including the Startup America DEMO Competition and the Connecticut Technology Council's Most Promising Software Product of the Year award.
Nxt-ID, Inc. is a technology company focused on developing and marketing innovative solutions for healthcare applications, payment systems, and the Internet of Things (IoT). Founded in 2011 and headquartered in Oxford, Connecticut, the company specializes in areas such as access control, biometric identity verification, security, encryption, and data protection. Through its subsidiary, LogicMark LLC, Nxt-ID manufactures and distributes both non-monitored and monitored personal emergency response systems, primarily targeting dealers, distributors, and the United States Department of Veterans Affairs. The company serves a diverse range of markets, including security, healthcare, financial technology, and IoT.
CyVek, Inc., established in 2008 and headquartered in Wallingford, Connecticut, specializes in developing a platform technology for measuring analytes in biological samples. The company offers an integrated test system comprising a microfluidic cartridge that enables the analysis of multiple biomarkers from minimal amounts of biological samples.
AxioMx
Venture Round in 2012
AxioMx Inc., founded in 2012 and based in Branford, Connecticut, specializes in the discovery, development, production, and delivery of recombinant antibodies. The company provides a comprehensive suite of custom antibody services, catering to the needs of life science researchers across diagnostic, pharmaceutical, biotechnology, and academic sectors. AxioMx's offerings include antigen and project design consultation, recombinant antibody development, antibody optimization, and protein production and purification services. Utilizing proprietary phage display libraries and affinity maturation techniques, the company excels in creating high-affinity, specific antibodies, including those for challenging targets such as phosphorylated proteins and non-immunogenic antigens. Additionally, AxioMx supports various antibody optimization processes, including scFv to IgG conversion and antibody labeling. The company is recognized for its innovative approach to synthetic recombinant antibodies, which serve vital roles in research, diagnostic tests, and therapeutic applications.
Deets, Inc. is a mobile technology company based in Westport, Connecticut, founded in 2011 by former leaders from prominent online companies. It specializes in a mobile communication application available for both Android and iPhone users. The application facilitates organized group messaging, private sharing, and the customization of multiple user profiles. Furthermore, it includes features such as push notifications for group interactions and a dynamic synchronization of contacts, allowing users to manage group conversations and collaboration from a unified mobile dashboard. Deets aims to enhance productivity and meaningful communication through its innovative solutions.
Innovatient Solutions
Debt Financing in 2012
Innovatient Solutions provides a patient engagement solution to the health care industry. They strive every day to enable patients to take more control of their health and to have more say in how they are cared for before, during, and after their hospital stay. It was founded in 2010 and headquartered in Farmington, Connecticut.
Lean Launch Ventures
Seed Round in 2012
Lean Launch Ventures (LLV) was established in 2012 in Weston, Connecticut, with the goal of providing an accelerator curriculum for entrepreneurs utilizing the Lean LaunchPad methodology developed by Steve Blank and Bob Dorf. The company focused on mentoring and investing in early-stage startups while also advising larger enterprises on innovation strategies. Through its initiatives, LLV aimed to support the growth of startups by delivering structured programs designed to enhance their development and potential for success. However, the firm ceased operations on December 31, 2018.
NovaTract Surgical
Series A in 2012
NovaTract Surgical, Inc. is a medical device company dedicated to enhancing minimally invasive surgical practices. Founded in 2010 and based in Madison, Connecticut, the company specializes in developing innovative solutions such as the NovaGrasp, a single-use laparoscopic grasper for tissue and organ retraction, and the NovaTract, a dynamic retractor designed for various surgical fields including colorectal, urologic, gynecologic, and robotic-assisted procedures. NovaTract Surgical aims to address the needs of the rapidly evolving fields of single-incision laparoscopic surgery and natural orifice transluminal endoscopic surgery, providing healthcare institutions with advanced tools to improve surgical outcomes.
BioRelix
Venture Round in 2012
BioRelix, Inc., a biopharmaceutical company, engages in the discovery and development of anti-biotic drug candidates for the treatment of infectious diseases in the United States. It develops a portfolio of riboswitch-based therapeutic agents to overcome the lethal and devastating causes of bacterial infections. The company was founded in 2005 and is based in New Haven, Connecticut.
eBrevia
Convertible Note in 2012
eBrevia Inc., established in 2011, specializes in developing artificial intelligence-driven software for legal professionals. Its primary products include Diligence Accelerator for streamlined due diligence processes, Contract Analyzer for efficient contract management, Lease Abstractor to simplify lease reviews, and Bespoke for custom term identification. These tools enable law firms and corporate legal departments to enhance accuracy, reduce time and costs associated with document review, and improve overall workflow efficiency. Headquartered in Stamford, Connecticut, with additional offices in San Francisco and New York, eBrevia operates as a subsidiary of Donnelley Financial Solutions Inc., following its acquisition in 2018. The company's innovative technology has been recognized through various awards, including the Startup America DEMO Competition and the Connecticut Technology Council's Most Promising Software Product of the Year award.
Umbie Health
Debt Financing in 2012
Umbie Health Corporation, an East Hartford, Conn.-based that develops a Web-based and mobile practice management application for dentists.