Connecticut Innovations, founded in 1989 and based in New Haven, Connecticut, is a venture capital investment firm focused on high-tech industries, including energy, biotechnology, information technology, and photonics. The firm provides strategic capital and operational insight to companies at various stages of development, from seed to later stages. Its investment strategy encompasses a wide range of sectors, such as SaaS, manufacturing, life sciences, clean tech, oncology, cybersecurity, infrastructure, big data, e-commerce, and other technology-based fields. Connecticut Innovations aims to be the primary source of financing and support for innovative companies in Connecticut, offering flexible financing solutions, strategic guidance, and valuable connections to help businesses succeed and grow.
Normunity is a biotechnology company focused on developing precision immuno-oncology medicines, specifically a new class known as immune normalizers. These medicines aim to target novel mechanisms that enhance the body’s natural immune response against cancer. In collaboration with the lab of Dr. Lieping Chen at Yale School of Medicine, Normunity is researching newly-discovered mechanisms of immune disruption in cancer, utilizing proprietary discovery platforms to explore the intricate interactions between cancer and the immune system. The company is advancing a pipeline of immune normalizers, which includes initial drug programs designed to address the exclusion of T-cells from immune-sensitive tumors and other factors that impede normal immune function in cancer. Normunity operates from locations in Boston, Massachusetts, and West Haven, Connecticut.
Quantum Circuits
Venture Round in 2024
Quantum Circuits, Inc. specializes in the development and manufacture of quantum computers utilizing superconducting devices. Founded in 2015 and located in New Haven, Connecticut, the company aims to innovate in the field of quantum computing by delivering full-stack systems that efficiently scale. Led by Dr. Robert Schoelkopf, a prominent figure in quantum science, Quantum Circuits employs a unique dual-rail quantum qubit design that incorporates built-in hardware error detection and conversion. This approach allows for a highly scalable error-corrected system, requiring significantly fewer physical qubits per logical qubit and providing a more efficient pathway to fault-tolerant quantum computing. By focusing on solid-state quantum bits, the company enables clients to perform error-free computations, thereby accelerating research and advancing the practical applications of quantum technology.
IntelliBoard
Venture Round in 2023
IntelliBoard, Inc. is a developer of a learning analytics platform focused on delivering insights and reporting services to educational institutions and corporate clients. Founded in 2015 and based in Monroe, Connecticut, IntelliBoard's platform integrates with various Learning Management Systems (LMS) to provide comprehensive data analysis tools. These tools enable faculty and management to access real-time data on learner engagement, performance, and the effectiveness of educational content. By presenting statistical data in an accessible format, including charts and formatted reports, IntelliBoard helps institutions make informed decisions, improve learning outcomes, and enhance operational efficiency. The company's mission is to empower clients to achieve their educational goals and maximize the return on their e-learning investments.
SLOOH
Venture Round in 2023
Slooh, LLC, founded in 2003 and based in Washington Depot, Connecticut, offers an innovative platform for public engagement in astronomy by providing online access to robotic telescopes located in various observatories worldwide. The company connects these telescopes to the internet, allowing users to view celestial events in real-time and participate in astronomical discoveries. Slooh has developed partnerships with institutions such as NASA and the Institute of Astrophysics of the Canary Islands, enhancing its credibility in the field. Through its automated observatories, Slooh has facilitated the capture of millions of celestial images and has broadcast live events like eclipses and asteroid observations, featuring expert narration. The platform is geared towards making astronomy accessible and affordable, particularly for educational institutions, enabling students and the public to explore the universe collaboratively with guidance from astronomy educators.
Inbox Health
Series B in 2023
Inbox Health Corp. is a digital healthcare company based in New Haven, Connecticut, founded in 2014. It specializes in developing a patient communication platform aimed at medical billers in the United States. The Inbox Health platform automates the patient communication process through bi-directional correspondence and utilizes proprietary algorithms, machine learning, and artificial intelligence. This enables patients to better understand their medical bills and access various payment options. By analyzing a wide range of data points across its customer base, the platform allows billers to personalize the billing, payment, and communication experiences for each patient, ultimately enhancing patient collections and overall satisfaction. The company's mission is to reduce administrative waste in healthcare by streamlining the billing and payment experience for patients.
Torigen Pharmaceuticals
Venture Round in 2022
Torigen Pharmaceuticals is dedicated to advancing cancer care for companion animals through innovative treatment options. Founded in 2013 and based in Farmington, Connecticut, the company focuses on developing immunotherapy solutions, particularly an experimental autologous cancer vaccine. This vaccine aims to activate the immune system to target specific tumor-associated antigens present on cancer cells, allowing for more effective detection and treatment of tumors. By providing alternatives to traditional, invasive methods such as surgeries and chemotherapy, Torigen seeks to improve the quality of life for pets facing cancer. The company builds on years of scientific research and is committed to pushing the boundaries of veterinary oncology.
Source Defense
Series B in 2022
Source Defense Ltd. specializes in website security software aimed at preventing attacks originating from third-party sources. Established in 2014 and headquartered in Rosh-ha’ayin, Israel, with additional offices in Beer-Sheva and Stamford, Connecticut, the company offers a real-time Software-as-a-Service platform. This platform empowers site owners to set and enforce permissions, receive real-time alerts, and monitor the behavior of third-party vendors on their sites. Source Defense provides tailored solutions for various sectors, including financial institutions, insurance companies, e-commerce, and content publishers. By focusing on prevention rather than detection, Source Defense helps organizations eliminate security concerns associated with third-party integrations, ultimately allowing them to concentrate on enhancing revenue opportunities while ensuring the safety and performance of their websites.
NourishedRx
Seed Round in 2022
NourishedRx is a provider of personalized food solutions aimed at health plan members and patients with diet-sensitive chronic health conditions, particularly those experiencing nutrition insecurity. Founded in 2019 in Stamford, Connecticut, the company delivers customized meal plans and meal prep kits tailored to individual eating habits. In addition to food solutions, NourishedRx offers educational resources and support to promote lasting behavior change, ultimately enhancing member engagement and satisfaction. The company's approach is designed to improve clinical outcomes and deliver significant cost savings for both individuals and healthcare systems.
Wellinks
Series C in 2021
Wellinks, Inc., established in 2014 and headquartered in New Haven, Connecticut, specializes in wearable health technology for orthotics and prosthetics. The company develops a smart strap for scoliosis braces, tracking wear duration and tightness, and providing real-time data to patients, parents, and doctors. This information enables better-informed treatment decisions, enhances patient motivation, and facilitates remote patient monitoring between clinical visits.
Lumeda
Series A in 2021
Lumeda Inc. is a biotechnology company focused on developing advanced photonic tools for intraoperative photodynamic therapy (PDT) to treat lung cancer. Founded in 2020 and based in Rocky Hill, Connecticut, the company aims to enhance the efficacy and ease of PDT procedures. Lumeda's innovative solutions include light delivery instrumentation and proprietary software that automates the delivery of light to targeted tumors with precise dosimetry profiles. By integrating advanced photonics with artificial intelligence, Lumeda's technology improves treatment planning and performance, allowing for a streamlined and reliable intraoperative PDT procedure. This approach not only addresses tumor margins during conventional non-small cell lung cancer resections but also seeks to reduce post-operative recurrence and improve overall patient outcomes.
Inbox Health
Series A in 2021
Inbox Health Corp. is a digital healthcare company based in New Haven, Connecticut, founded in 2014. It specializes in developing a patient communication platform aimed at medical billers in the United States. The Inbox Health platform automates the patient communication process through bi-directional correspondence and utilizes proprietary algorithms, machine learning, and artificial intelligence. This enables patients to better understand their medical bills and access various payment options. By analyzing a wide range of data points across its customer base, the platform allows billers to personalize the billing, payment, and communication experiences for each patient, ultimately enhancing patient collections and overall satisfaction. The company's mission is to reduce administrative waste in healthcare by streamlining the billing and payment experience for patients.
Artizan Biosciences
Series A in 2021
Artizan Biosciences, Inc. is a biotechnology company based in New Haven, Connecticut, founded in 2016. The company focuses on developing small molecule drugs aimed at treating serious diseases linked to intestinal inflammation. Utilizing its proprietary IgA-SEQ technology platform, Artizan distinguishes disease-driving bacteria within the intestinal microbiota. This innovative approach enables the development of precision therapeutics designed to address unmet medical needs in various conditions, including digestive disorders, obesity, autoimmune diseases, and disorders affecting the skin, lungs, and central nervous system. Through its research, Artizan aims to provide new and potentially curative treatment options for patients suffering from these diverse health challenges.
BioRez
Seed Round in 2020
Biorez, Inc. is a medical device company specializing in the development of bioresorbable scaffold implants aimed at regenerating functional tissue in vivo. Founded in 2008 and based in New Haven, Connecticut, Biorez offers innovative products such as an off-the-shelf implant for anterior cruciate ligament (ACL) reconstruction, which eliminates the need for harvesting donor tissue and serves as a superior alternative to cadaver-based materials. The company's technology utilizes a degradable polymer, specifically PLLA, to create implants that stabilize surgical repairs and facilitate the body's natural tissue regeneration, thereby enhancing musculoskeletal outcomes. Among its product lineup is the L-C Ligament® and the biorez GRAFT™, an FDA-cleared device designed for soft tissue augmentation of the rotator cuff. By leveraging this technology, Biorez aims to accelerate patient recovery and improve surgical outcomes in orthopedic procedures.
Simcha Therapeutics
Series A in 2020
Simcha Therapeutics is a biopharmaceutical company focused on developing engineered cytokine immunotherapies for cancer treatment. Based in New Haven, Connecticut, the company employs directed evolution to create novel cytokines aimed at enhancing the immune system's ability to combat diseases. Its lead program, ST-067, is a designer IL-18 cytokine that has demonstrated significant antitumor activity in animal studies, both as a standalone treatment and in combination with anti-PD-1 checkpoint inhibitors. Founded in 2018, Simcha Therapeutics is dedicated to advancing innovative therapies that empower patients to effectively fight cancer.
IntelliBoard
Series A in 2020
IntelliBoard, Inc. is a developer of a learning analytics platform focused on delivering insights and reporting services to educational institutions and corporate clients. Founded in 2015 and based in Monroe, Connecticut, IntelliBoard's platform integrates with various Learning Management Systems (LMS) to provide comprehensive data analysis tools. These tools enable faculty and management to access real-time data on learner engagement, performance, and the effectiveness of educational content. By presenting statistical data in an accessible format, including charts and formatted reports, IntelliBoard helps institutions make informed decisions, improve learning outcomes, and enhance operational efficiency. The company's mission is to empower clients to achieve their educational goals and maximize the return on their e-learning investments.
CytoVeris
Venture Round in 2020
CytoVeris is a company focused on developing optical-based technologies to assist surgical oncologists in identifying and removing tumor tissue during cancer resection surgeries. Founded in 2018 by Alan Kersey in Farmington, Connecticut, CytoVeris aims to enhance the surgeon's ability to achieve clean margins, thereby improving patient outcomes. The company’s devices facilitate real-time assessment of tissue and generate molecular-specific information by detecting unique signatures created by cancer cells that alter cellular metabolic processes. This includes variations in lipids, proteins, and metabolites, which can be identified using their OncoMap system. By providing oncologists with critical information during surgery, CytoVeris seeks to reduce healthcare costs associated with repeat surgeries.
Mindnest Health
Seed Round in 2020
MindNest Health, Inc. is a Connecticut-based company founded in 2016 that develops a digital platform for parent training, enabling caregivers to implement clinically validated behavioral interventions for children with conditions such as ADHD, autism, and disruptive behaviors. The platform aims to promote children's development by providing evidence-based solutions that address behavioral health challenges, including anxiety and depression. MindNest Health's approach seeks to eliminate barriers parents face when seeking help, thereby enhancing access to care for their children and reducing stress for families. Additionally, the company is focused on decreasing the overall cost of care for employers and payers, with a vision of fostering an environment where children and families can thrive.
Inbox Health
Venture Round in 2020
Inbox Health Corp. is a digital healthcare company based in New Haven, Connecticut, founded in 2014. It specializes in developing a patient communication platform aimed at medical billers in the United States. The Inbox Health platform automates the patient communication process through bi-directional correspondence and utilizes proprietary algorithms, machine learning, and artificial intelligence. This enables patients to better understand their medical bills and access various payment options. By analyzing a wide range of data points across its customer base, the platform allows billers to personalize the billing, payment, and communication experiences for each patient, ultimately enhancing patient collections and overall satisfaction. The company's mission is to reduce administrative waste in healthcare by streamlining the billing and payment experience for patients.
P2 Science
Series C in 2020
P2 Science, Inc. is a bio-renewable chemistry company based in Woodbridge, Connecticut, specializing in the development and production of specialty chemicals derived from renewable feedstocks, such as vegetable oils. Founded in 2009 by a team that includes Yale scientists and an experienced chemical industry executive, the company focuses on creating high-value ingredients for flavors, fragrances, cosmetics, and other applications. P2 Science aims to provide sustainable alternatives to traditional petrochemical products, catering to diverse markets, including personal care, household cleaning, agriculture, and environmental remediation. Their innovative technology enables the conversion of renewable resources into cost-effective chemical solutions, addressing the increasing demand for greener options among major users in the specialty chemicals sector. The company also maintains a laboratory in New Haven, Connecticut, to support ongoing research and partnerships throughout the supply chain.
Enviro Power
Series A in 2020
Enviro Power, LLC, founded in 2013 and based in Hartford, Connecticut, specializes in the development and marketing of innovative heating equipment for both residential and commercial applications. The company offers two main products: the Commercial SmartWatt Boiler, designed for light-commercial and high-end residential settings, and the Residential SmartWatt Boiler for home use. Enviro Power's SmartWatt Boiler technology platform not only meets heating requirements but also generates electricity at nearly zero cost, providing backup power and enhancing grid stability. This system allows building owners to potentially reduce utility bills while simultaneously lowering their carbon footprint and contributing to improved grid resiliency.
IsoPlexis
Series C in 2020
IsoPlexis is a life science technology company based in Branford, Connecticut, founded in 2013. It focuses on developing a single-cell detection system that identifies patient immune responses at the single-cell level. This innovative platform enables the assessment of therapeutic safety and efficacy, as well as the monitoring of disease progression. IsoPlexis specializes in cell-based proteomic systems and biomarkers, providing insights into functional protein biology and cellular signaling networks with high resolution. By offering these capabilities, the company aids in predicting patient responses to novel immunotherapies and cellular therapies, ultimately enhancing therapeutic development and informing clinical decisions.
Wellinks
Series B in 2019
Wellinks, Inc., established in 2014 and headquartered in New Haven, Connecticut, specializes in wearable health technology for orthotics and prosthetics. The company develops a smart strap for scoliosis braces, tracking wear duration and tightness, and providing real-time data to patients, parents, and doctors. This information enables better-informed treatment decisions, enhances patient motivation, and facilitates remote patient monitoring between clinical visits.
Budderfly
Venture Round in 2019
Budderfly, Inc. is a company based in Shelton, Connecticut, that specializes in energy management systems designed to optimize energy consumption for various facilities, including office buildings, retail stores, schools, healthcare facilities, and restaurants. Established in 2007, Budderfly offers a comprehensive Energy-as-a-Service model that incorporates proprietary energy intelligence software and a range of energy-efficient technology upgrades. This includes the deployment of IoT devices, LED lighting, HVAC controls, and refrigeration systems to monitor and manage energy usage effectively. By implementing these solutions at no upfront cost to clients, Budderfly not only delivers immediate energy expense savings but also ensures ongoing maintenance and updates to prevent obsolescence in energy infrastructure. The company's approach contributes to significant reductions in carbon footprints while enhancing the overall efficiency of energy consumption in client facilities.
Inbox Health
Seed Round in 2019
Inbox Health Corp. is a digital healthcare company based in New Haven, Connecticut, founded in 2014. It specializes in developing a patient communication platform aimed at medical billers in the United States. The Inbox Health platform automates the patient communication process through bi-directional correspondence and utilizes proprietary algorithms, machine learning, and artificial intelligence. This enables patients to better understand their medical bills and access various payment options. By analyzing a wide range of data points across its customer base, the platform allows billers to personalize the billing, payment, and communication experiences for each patient, ultimately enhancing patient collections and overall satisfaction. The company's mission is to reduce administrative waste in healthcare by streamlining the billing and payment experience for patients.
Cybrexa Therapeutics
Series B in 2019
Cybrexa, Inc. is focused on developing innovative DNA repair inhibitors aimed at enhancing cancer therapeutics through the use of peptide-based technology that directly targets the tumor microenvironment. Established in 2016 and based in New Haven, Connecticut, the company leverages a unique tumor-localizing peptide technology developed at Yale University. This approach aims to revolutionize drug delivery by improving the therapeutic index, allowing for safer administration of higher doses of chemotherapy and radiotherapy. Cybrexa's pipeline includes a collection of small molecule inhibitors that can be combined with existing anticancer agents, thereby expanding treatment options for patients and addressing significant unmet medical needs in oncology. Through its research, Cybrexa seeks to improve patient outcomes and redefine the landscape of cancer treatment.
PayVeris
Series D in 2019
Payveris, LLC operates a cloud-based digital payment and money transfer platform aimed at serving financial institutions and their partners. Founded in 2011 and headquartered in Cromwell, Connecticut, Payveris provides a range of services including consumer and business bill payment solutions, account-to-account external transfers, and person-to-person payment capabilities. Customers can easily send money from their bank or credit union accounts to others via the web, smartphones, or tablets. The platform also features PayWatch, an integrated fraud prevention solution that monitors transactions across various payment types, and PayItNow, which connects financial institutions, merchants, and consumers in the payment process. Payveris has established strategic partnerships with Kony and Corelation to enhance its offerings.
IsoPlexis
Series C in 2019
IsoPlexis is a life science technology company based in Branford, Connecticut, founded in 2013. It focuses on developing a single-cell detection system that identifies patient immune responses at the single-cell level. This innovative platform enables the assessment of therapeutic safety and efficacy, as well as the monitoring of disease progression. IsoPlexis specializes in cell-based proteomic systems and biomarkers, providing insights into functional protein biology and cellular signaling networks with high resolution. By offering these capabilities, the company aids in predicting patient responses to novel immunotherapies and cellular therapies, ultimately enhancing therapeutic development and informing clinical decisions.
Allyx Therapeutics
Convertible Note in 2019
Allyx Therapeutics, founded in 2018 and based in Durham, Connecticut, is a clinical-stage biotechnology company focused on developing disease-modifying treatments for Alzheimer's Disease. The company’s primary product is an orally bioavailable small molecule that functions as a silent allosteric modulator of mGluR5. This innovative drug aims to reverse neurodegeneration and offers a potential approach to preserve cognitive function in patients with Alzheimer's. By targeting the underlying mechanisms of the disease, Allyx Therapeutics strives to provide effective therapeutic solutions for those affected by neurodegenerative disorders.
Torigen Pharmaceuticals
Series A in 2019
Torigen Pharmaceuticals is dedicated to advancing cancer care for companion animals through innovative treatment options. Founded in 2013 and based in Farmington, Connecticut, the company focuses on developing immunotherapy solutions, particularly an experimental autologous cancer vaccine. This vaccine aims to activate the immune system to target specific tumor-associated antigens present on cancer cells, allowing for more effective detection and treatment of tumors. By providing alternatives to traditional, invasive methods such as surgeries and chemotherapy, Torigen seeks to improve the quality of life for pets facing cancer. The company builds on years of scientific research and is committed to pushing the boundaries of veterinary oncology.
Phlatbed
Venture Round in 2019
Phlatbed Inc. is a consumer logistics company that developed an on-demand moving application designed to connect users with local drivers for transporting items. Founded in 2016 and based in Norwalk, Connecticut, the platform allows customers to place real-time requests and select from multiple drivers who can assist with moving, packing, loading, and junk removal. By centralizing moving requests based on geographic preferences and pricing, Phlatbed enhances accessibility and efficiency in the logistics sector. Payments are processed automatically through various methods, including credit cards and PayPal, upon completion of the service. The platform operates across the United States and Canada, with plans to expand into the United Kingdom. Additionally, Phlatbed maintains an active blog and social media presence to engage with the community and provide updates on its services.
Bactana
Series A in 2019
Bactana Corporation focuses on researching and developing nutritional products aimed at enhancing microbiome health in livestock and pets. The company has created a product platform called FPS-4, which leverages the beneficial interaction between an animal’s immune system and metabolism to boost productivity while ensuring good health. Bactana's approach includes identifying and isolating beneficial molecules from anaerobic bacteria found in the animal microbiome. The company also targets metabolic conditions and digestive disorders in pets, aiming to develop therapies for issues such as prediabetes and diabetes. Additionally, Bactana is committed to creating sustainable products that reduce the reliance on antibiotics and conserve natural resources in livestock production. Founded in 2016 and headquartered in Farmington, Connecticut, Bactana serves cattle farmers primarily in Connecticut and New York.
Source Defense
Series A in 2018
Source Defense Ltd. specializes in website security software aimed at preventing attacks originating from third-party sources. Established in 2014 and headquartered in Rosh-ha’ayin, Israel, with additional offices in Beer-Sheva and Stamford, Connecticut, the company offers a real-time Software-as-a-Service platform. This platform empowers site owners to set and enforce permissions, receive real-time alerts, and monitor the behavior of third-party vendors on their sites. Source Defense provides tailored solutions for various sectors, including financial institutions, insurance companies, e-commerce, and content publishers. By focusing on prevention rather than detection, Source Defense helps organizations eliminate security concerns associated with third-party integrations, ultimately allowing them to concentrate on enhancing revenue opportunities while ensuring the safety and performance of their websites.
Inbox Health
Seed Round in 2018
Inbox Health Corp. is a digital healthcare company based in New Haven, Connecticut, founded in 2014. It specializes in developing a patient communication platform aimed at medical billers in the United States. The Inbox Health platform automates the patient communication process through bi-directional correspondence and utilizes proprietary algorithms, machine learning, and artificial intelligence. This enables patients to better understand their medical bills and access various payment options. By analyzing a wide range of data points across its customer base, the platform allows billers to personalize the billing, payment, and communication experiences for each patient, ultimately enhancing patient collections and overall satisfaction. The company's mission is to reduce administrative waste in healthcare by streamlining the billing and payment experience for patients.
Tunxis Community College
Grant in 2018
In the Farmington, Connecticut area, Tunxis Community College has academic, workforce training, and personal enrichment courses for students with all sorts of different interests that can earn you an associate’s degree or certificate. Among the many majors to choose from are programs such as Allied Health, Graphic Design, Visual Fine Arts, Business Office Technology, Computer Information Systems, Criminal Justice, Drug and Alcohol Recovery Counselor, Early Childhood Education, Engineering Science and Technology Studies, and New Media Communication, as well as many more. Counselors in the financial aid office can point you toward programs that will help you earn loans, grants, scholarships, veteran’s benefits, and more if you qualify. These financial aid options can help you pay for tuition and other expenses. Student life at TCC includes a student lounge, The Cyber Café, and the Barnes-Franklin Gallery, which is filled with student, community, and professional art. Academic advising is available for any student who needs help. The career center can help students find employment. Other student resources includes child care, health care, media center, and student activities.
Phlatbed
Venture Round in 2018
Phlatbed Inc. is a consumer logistics company that developed an on-demand moving application designed to connect users with local drivers for transporting items. Founded in 2016 and based in Norwalk, Connecticut, the platform allows customers to place real-time requests and select from multiple drivers who can assist with moving, packing, loading, and junk removal. By centralizing moving requests based on geographic preferences and pricing, Phlatbed enhances accessibility and efficiency in the logistics sector. Payments are processed automatically through various methods, including credit cards and PayPal, upon completion of the service. The platform operates across the United States and Canada, with plans to expand into the United Kingdom. Additionally, Phlatbed maintains an active blog and social media presence to engage with the community and provide updates on its services.
ReNetX Bio
Series A in 2018
ReNetX Bio, Inc. is a biotechnology company focused on developing therapeutics for injuries and damage to the central nervous system (CNS). Its primary product, Nogo Trap, is a decoy receptor that binds to growth inhibitors, facilitating the natural growth of nerve fibers and promoting processes such as axonal regeneration, axonal sprouting, and synaptic plasticity. The company's treatments address various CNS conditions, including spinal cord injury, stroke recovery, and glaucoma. Additionally, ReNetX Bio is involved in developing disease-modifying therapeutics aimed at conditions like Alzheimer's disease, utilizing small molecule oral compounds that inhibit the binding of β-amyloid oligomers in the brain. Founded in 2009 and based in New Haven, Connecticut, the company was previously known as Axerion Therapeutics, Inc. before rebranding in July 2017.
OncoSynergy
Series A in 2018
OncoSynergy, a spin-out from the University of California, San Francisco, focuses on developing innovative immunotherapies aimed at enhancing outcomes for cancer patients with unmet medical needs. Founded in 2011 and based in Greenwich, Connecticut, the company specializes in Resistance Mechanism Inhibitors (RMIs), a novel class of therapeutics that target multiple pathways associated with cancer progression. This approach has shown significant preclinical efficacy both as standalone treatments and in strategic combinations, offering the potential for more durable patient outcomes and cures. By addressing several cancer-driving mechanisms simultaneously, OncoSynergy aims to transform the landscape of cancer treatment.
Rallybio
Series A in 2018
Rallybio is a clinical-stage biopharmaceutical company focused on developing transformative therapies for patients with severe and rare disorders. Founded in 2018 and based in New Haven, Connecticut, the company is advancing its lead product candidate, RLYB211, which aims to prevent fetal and neonatal alloimmune thrombocytopenia (FNAIT), a serious condition that can lead to uncontrolled bleeding in fetuses and newborns. Rallybio's portfolio includes a range of promising product candidates targeting rare diseases across various therapeutic areas, including hematology, immuno-inflammation, maternal-fetal health, and metabolic disorders. The company's efforts are supported by a team of experienced professionals with extensive expertise in biopharma research and development.
GoNation
Venture Round in 2018
GoNation LLC operates a mobile platform designed to enhance the connection between users and local businesses across several states, including Connecticut, Massachusetts, Louisiana, California, and New York. Founded in 2011 and headquartered in Milford, Connecticut, the company offers personalized user profiles that facilitate sharing, saving, and discovering information about local enterprises. GoNation aims to empower small businesses by providing innovative technology and data-driven tools that streamline online operations, increase revenue, and foster customer relationships. By integrating aspects of social media and search functionalities, the platform serves as a comprehensive local discovery tool, enabling users to explore their communities effectively while helping businesses strengthen their digital presence.
FallCall Solutions
Seed Round in 2018
FallCall Solutions, LLC specializes in developing fall detection and telemonitoring applications aimed at enhancing the safety and communication between the elderly and their caregivers. Founded in 2015 and based in Trumbull, Connecticut, the company's flagship product, FallCall Now, is designed to differentiate between low and high mechanism falls and can alert family members and emergency services when a fall occurs. Additionally, the ElderCheck Now application facilitates communication between the geriatric population and their caregivers, promoting independence for seniors while providing peace of mind for caregivers. By utilizing widely adopted mobile platforms, FallCall Solutions focuses on creating user-friendly software that caters to the specific needs of its consumers, enabling elders to maintain active and independent lifestyles while ensuring they have access to necessary support.
BioRez
Series C in 2018
Biorez, Inc. is a medical device company specializing in the development of bioresorbable scaffold implants aimed at regenerating functional tissue in vivo. Founded in 2008 and based in New Haven, Connecticut, Biorez offers innovative products such as an off-the-shelf implant for anterior cruciate ligament (ACL) reconstruction, which eliminates the need for harvesting donor tissue and serves as a superior alternative to cadaver-based materials. The company's technology utilizes a degradable polymer, specifically PLLA, to create implants that stabilize surgical repairs and facilitate the body's natural tissue regeneration, thereby enhancing musculoskeletal outcomes. Among its product lineup is the L-C Ligament® and the biorez GRAFT™, an FDA-cleared device designed for soft tissue augmentation of the rotator cuff. By leveraging this technology, Biorez aims to accelerate patient recovery and improve surgical outcomes in orthopedic procedures.
GoNation
Funding Round in 2017
GoNation LLC operates a mobile platform designed to enhance the connection between users and local businesses across several states, including Connecticut, Massachusetts, Louisiana, California, and New York. Founded in 2011 and headquartered in Milford, Connecticut, the company offers personalized user profiles that facilitate sharing, saving, and discovering information about local enterprises. GoNation aims to empower small businesses by providing innovative technology and data-driven tools that streamline online operations, increase revenue, and foster customer relationships. By integrating aspects of social media and search functionalities, the platform serves as a comprehensive local discovery tool, enabling users to explore their communities effectively while helping businesses strengthen their digital presence.
LambdaVision
Series A in 2017
LambdaVision, Incorporated is dedicated to designing and developing a protein-based artificial retina with the goal of restoring vision for individuals suffering from advanced retinal degenerative diseases, such as retinitis pigmentosa and age-related macular degeneration. Founded in 2009 and based in Farmington, Connecticut, the company is focused on commercializing a retinal implant that employs a light-activated protein, bacteriorhodopsin, to stimulate the retinas of patients experiencing impaired vision or significant sight loss. This innovative technology aims to enhance the quality of life for millions affected by these conditions.
Wellinks
Venture Round in 2017
Wellinks, Inc., established in 2014 and headquartered in New Haven, Connecticut, specializes in wearable health technology for orthotics and prosthetics. The company develops a smart strap for scoliosis braces, tracking wear duration and tightness, and providing real-time data to patients, parents, and doctors. This information enables better-informed treatment decisions, enhances patient motivation, and facilitates remote patient monitoring between clinical visits.
Edge2Web
Convertible Note in 2017
Edge2Web, Inc. specializes in providing cloud-based visual tools that empower industrial application builders to quickly develop, assemble, and deploy various IIoT-style applications. Founded in 2016 and headquartered in Woodbury, Connecticut, the company offers Edge2Web Director, which enables industrial domain experts to create sophisticated dashboards and mash-up applications. Its low-code solutions facilitate the development of interactive machine and plant monitors, device-connected diagnostic guides, and manufacturing process dashboards. By integrating data and applications across operational technology (OT), information technology (IT), and enterprise cloud environments, Edge2Web's tools minimize IT disruption and allow for rapid scaling to meet diverse industrial needs. This approach helps equipment manufacturers, systems integrators, and industrial experts deliver actionable insights to end users, ultimately enhancing operational performance.
IsoPlexis
Series B in 2017
IsoPlexis is a life science technology company based in Branford, Connecticut, founded in 2013. It focuses on developing a single-cell detection system that identifies patient immune responses at the single-cell level. This innovative platform enables the assessment of therapeutic safety and efficacy, as well as the monitoring of disease progression. IsoPlexis specializes in cell-based proteomic systems and biomarkers, providing insights into functional protein biology and cellular signaling networks with high resolution. By offering these capabilities, the company aids in predicting patient responses to novel immunotherapies and cellular therapies, ultimately enhancing therapeutic development and informing clinical decisions.
The Big Willow
Convertible Note in 2017
The Big Willow, Inc. is a company that specializes in designing and developing platforms for marketing teams, focusing on uncovering buyer intent through advanced data processing. By indexing content consumption across web sessions, The Big Willow connects off-site behaviors to activity data from various marketing and customer relationship management tools. Its product offerings include a B2B-centric programmatic advertising platform, account-based marketing solutions, and various Adtech and Paid Media Solutions aimed at pre-targeted advertising and custom content syndication for prospects demonstrating buyer intent. Additionally, the company provides Martech Solutions to support account-based marketing initiatives and Sales Enablement Solutions to enhance deal flow and revenue generation from qualified leads. Founded in 2013 and headquartered in Wilton, Connecticut, The Big Willow operates as a subsidiary of Aberdeen Group LLC.
Cybrexa Therapeutics
Series B in 2017
Cybrexa, Inc. is focused on developing innovative DNA repair inhibitors aimed at enhancing cancer therapeutics through the use of peptide-based technology that directly targets the tumor microenvironment. Established in 2016 and based in New Haven, Connecticut, the company leverages a unique tumor-localizing peptide technology developed at Yale University. This approach aims to revolutionize drug delivery by improving the therapeutic index, allowing for safer administration of higher doses of chemotherapy and radiotherapy. Cybrexa's pipeline includes a collection of small molecule inhibitors that can be combined with existing anticancer agents, thereby expanding treatment options for patients and addressing significant unmet medical needs in oncology. Through its research, Cybrexa seeks to improve patient outcomes and redefine the landscape of cancer treatment.
Trinity Mobile Networks
Venture Round in 2017
Trinity Mobile Networks, Inc. specializes in developing advanced networking solutions aimed at enhancing mobile connectivity. The company has created a multi-network overlay SDN platform, known as TrinitySDN, which integrates cellular, Wi-Fi, and mesh connections specifically designed for smartphones and other mobile devices with multiple interfaces. This platform empowers network operators with tools for unified monitoring across various connection types, enabling features such as software-defined multipath transmissions, seamless network handoffs, and real-time diagnostics for network performance. Additionally, Trinity Mobile Networks has developed wireless mesh networking technologies and a corresponding Android application that allows users to access high-quality, affordable mesh connections, thereby reducing dependence on costly cellular services. Founded in 2014 and headquartered in New Haven, Connecticut, the company is committed to improving data speeds and overall network bandwidth while optimizing traffic across existing infrastructure.
Bactana
Seed Round in 2017
Bactana Corporation focuses on researching and developing nutritional products aimed at enhancing microbiome health in livestock and pets. The company has created a product platform called FPS-4, which leverages the beneficial interaction between an animal’s immune system and metabolism to boost productivity while ensuring good health. Bactana's approach includes identifying and isolating beneficial molecules from anaerobic bacteria found in the animal microbiome. The company also targets metabolic conditions and digestive disorders in pets, aiming to develop therapies for issues such as prediabetes and diabetes. Additionally, Bactana is committed to creating sustainable products that reduce the reliance on antibiotics and conserve natural resources in livestock production. Founded in 2016 and headquartered in Farmington, Connecticut, Bactana serves cattle farmers primarily in Connecticut and New York.
Inbox Health
Seed Round in 2017
Inbox Health Corp. is a digital healthcare company based in New Haven, Connecticut, founded in 2014. It specializes in developing a patient communication platform aimed at medical billers in the United States. The Inbox Health platform automates the patient communication process through bi-directional correspondence and utilizes proprietary algorithms, machine learning, and artificial intelligence. This enables patients to better understand their medical bills and access various payment options. By analyzing a wide range of data points across its customer base, the platform allows billers to personalize the billing, payment, and communication experiences for each patient, ultimately enhancing patient collections and overall satisfaction. The company's mission is to reduce administrative waste in healthcare by streamlining the billing and payment experience for patients.
SmartPay Solutions
Series A in 2016
SmartPay Solutions LLC, founded in 2010 and based in Southington, Connecticut, specializes in providing a cloud-based software solution for pay-as-you-go workers’ compensation plans. The SmartPay platform is designed for insurance carriers, independent agents, and payroll providers, offering a flexible and user-friendly system that enables immediate access to essential services. The company's technology aims to streamline the workers' compensation process, ensuring that it meets the diverse needs of its clients. By leveraging innovative software, SmartPay Solutions enhances the efficiency and effectiveness of pay-as-you-go workers’ compensation administration.
Cadenza Innovation
Series A in 2016
Cadenza Innovation, Inc. specializes in the design and manufacturing of lithium-ion batteries tailored for electric vehicles. Founded in 2012 and located in Wilton, Connecticut, the company, previously known as Cloteam LLC, offers a patented battery architecture that merges the characteristics of both wound jelly rolls and large prismatic cells. This innovative design significantly enhances energy density while maintaining low production costs. Cadenza Innovation focuses on providing reliable and safe energy storage solutions, which are suitable for various applications, including power backup for hybrid, off-grid, and grid-connected telecom sites. Their technology emphasizes performance, long cycle life, and options for high-temperature operation, while also allowing for real-time monitoring to enhance safety and reliability in the global energy market.
PayVeris
Venture Round in 2016
Payveris, LLC operates a cloud-based digital payment and money transfer platform aimed at serving financial institutions and their partners. Founded in 2011 and headquartered in Cromwell, Connecticut, Payveris provides a range of services including consumer and business bill payment solutions, account-to-account external transfers, and person-to-person payment capabilities. Customers can easily send money from their bank or credit union accounts to others via the web, smartphones, or tablets. The platform also features PayWatch, an integrated fraud prevention solution that monitors transactions across various payment types, and PayItNow, which connects financial institutions, merchants, and consumers in the payment process. Payveris has established strategic partnerships with Kony and Corelation to enhance its offerings.
Wellinks
Venture Round in 2016
Wellinks, Inc., established in 2014 and headquartered in New Haven, Connecticut, specializes in wearable health technology for orthotics and prosthetics. The company develops a smart strap for scoliosis braces, tracking wear duration and tightness, and providing real-time data to patients, parents, and doctors. This information enables better-informed treatment decisions, enhances patient motivation, and facilitates remote patient monitoring between clinical visits.
ShopLandia
Convertible Note in 2015
ShopLandia, Inc. is a company based in Stamford, Connecticut, founded in 2014. It specializes in a mobile application that provides a unique shoppable video platform, allowing users to create, edit, and stream product videos for online sales. The platform features end-to-end SaaS capabilities, enabling customization of videos with music, filters, and special effects. By facilitating both recorded and live video, ShopLandia supports peer-to-peer buying and selling, empowering users to showcase their products effectively and efficiently.
Arccos Golf
Venture Round in 2015
Arccos Golf, LLC, founded in 2012 and headquartered in Stamford, Connecticut, specializes in developing and marketing sensor-based products and mobile applications aimed at enhancing golfers' performance. The company's flagship Arccos Caddie platform offers features such as automatic shot tracking, smart distance club averages, an AI-powered GPS rangefinder, advanced analytics, and personalized caddie advice. By utilizing sensors attached to golf clubs, along with a mobile application and web dashboard, Arccos Golf enables golfers to monitor key performance metrics, including clubhead speed and face angle, facilitating data-driven insights for improvement. This innovative approach caters to golfers of all skill levels, helping them make informed decisions on the course and ultimately lower their scores.
Chiefofstaff.com
Convertible Note in 2015
Chiefofstaff.com LLC operates a cloud-based strategic plan management platform designed to assist organizations in measuring, monitoring, and managing the implementation of their strategic plans. Based in Hartford, Connecticut, with additional offices in major cities worldwide, the platform provides real-time feedback and insights for executives, particularly CEOs, enabling them to make informed decisions by offering a comprehensive overview of plan progress. It facilitates communication between top management and front-line managers, allowing for effective execution and alignment of strategic initiatives across various departments. The platform is intuitive, customizable, and scalable, catering to the needs of complex organizations. Clients include notable organizations such as New York Life Mexico, Zodiac Aerospace, and Deloitte. Founded by Robert Epner, the platform is designed to streamline strategy execution across multiple countries and businesses, enhancing operational efficiency and transparency.
SeeClickFix
Venture Round in 2015
SeeClickFix, Inc. is a communications platform designed to facilitate the reporting of non-emergency issues by citizens and enable governments to effectively track, manage, and respond to these reports. The company provides a suite of tools aimed at enhancing transparency, collaboration, and civic engagement within communities. Key offerings include Request Management for efficient data collection and communication, Work Management for managing assignments and internal communication, and Citizen Engagement tools that keep residents informed. Additionally, SeeClickFix offers data analytics solutions to measure success and provide insights for decision-making. The platform is designed to accommodate various community sizes and budgets, thereby empowering citizens and government entities to work together toward improving neighborhoods. Founded in 2007 and based in New Haven, Connecticut, SeeClickFix operates as a subsidiary of CivicPlus, LLC.
NorthPage
Venture Round in 2015
NorthPage Inc. offers a cloud-based digital marketing optimization platform designed to assist enterprise marketing organizations in enhancing their digital performance. Founded in 2007 and headquartered in Southbury, Connecticut, the company provides tools for performance benchmarking, competitive analysis, and best-practice guidance across various digital channels. Its solutions focus on optimizing websites, e-commerce sites, mobile marketing, social media, search engine marketing, content marketing, and e-retail programs. NorthPage serves a diverse range of industries, including retail, financial services, consumer products, pharmaceuticals, and technology. The platform leverages cognitive marketing analytics and an algorithmic approach to provide actionable insights that help marketers improve customer journeys, user experiences, engagement, and conversion rates.
Cafe Learn
Seed Round in 2015
Cafe Learn LLC, based in Stamford, Connecticut, is a subsidiary of O'Donnell Group LLC that specializes in a cloud-based Software-as-a-Service platform designed for educational institutions. Founded in 2015, Cafe Learn's platform empowers instructors to create, share, and customize blended, social, and personalized courses for students. The platform focuses on enhancing student success by offering content flexibility and real-time data on student mastery of measurable outcomes. By facilitating a more engaging learning experience, Cafe Learn aims to support schools in evolving their teaching methods and improving overall educational outcomes.
Device42
Seed Round in 2015
Device42, Inc. is a software company that specializes in providing solutions for system, network, and data center engineers, as well as IT managers. Founded in 2010 and headquartered in West Haven, Connecticut, with an additional office in Boston, Massachusetts, Device42 offers a comprehensive suite of tools designed for IT inventory management, patch panel cable management, data center power management, and IP address tracking. Its platform includes essential features such as Configuration Management Database (CMDB), Application Dependency Mapping (ADM), and a DCIM Software Marketplace, all aimed at helping organizations maintain accurate inventories of both IP-based and non-IP assets. The software facilitates various IT operations, compliance auditing, migration, and modernization processes, making it easier for clients to manage hybrid IT environments and execute successful cloud migrations while ensuring compliance with internal and external regulations.
eBrevia
Seed Round in 2014
eBrevia, Inc. specializes in artificial intelligence-driven software designed for legal applications, including due diligence, contract management, lease abstraction, and document drafting. The company's offerings include the Diligence Accelerator, which helps attorneys efficiently navigate the due diligence process by extracting relevant content from legal documents and populating summary templates. Additionally, the eBrevia Contract Analyzer aids organizations in storing, retrieving, and analyzing contracts, while the Lease Abstractor streamlines the lease review process by highlighting pertinent information. eBrevia Bespoke further enhances this by identifying custom terms within legal documents. Founded in 2011 and headquartered in Stamford, Connecticut, with additional offices in San Francisco and New York, eBrevia serves law firms and corporate legal departments. The company has received recognition for its innovative technology, including awards from the Connecticut Technology Council and accolades at national competitions. eBrevia operates as a subsidiary of Donnelley Financial Solutions, Inc.
Fitscript
Seed Round in 2014
Fitscript LLC is a Connecticut-based company that specializes in providing digital exercise programs aimed at diabetes prevention and weight management. Through its application, GlucoseZone, the company offers a range of online videos, including total body workouts, chair exercises, core training, and yoga specifically designed for individuals managing diabetes. The platform tailors exercise guidance based on users' real-time glucose levels, diabetes conditions, and fitness goals, catering to both type 1 and type 2 diabetes. For type 1 diabetes, it focuses on stabilizing glucose fluctuations, while for type 2 diabetes, it emphasizes weight loss through structured exercise programs. Originally founded as Exerscrip LLC in 2010, the company rebranded to Fitscript in April 2016 and was launched by Charles O’Connell.
Wellinks
Seed Round in 2014
Wellinks, Inc., established in 2014 and headquartered in New Haven, Connecticut, specializes in wearable health technology for orthotics and prosthetics. The company develops a smart strap for scoliosis braces, tracking wear duration and tightness, and providing real-time data to patients, parents, and doctors. This information enables better-informed treatment decisions, enhances patient motivation, and facilitates remote patient monitoring between clinical visits.
GestVision
Seed Round in 2014
GestVision, Inc. develops a diagnostic test aimed at detecting preeclampsia in pregnant women, a condition marked by high blood pressure and protein in the urine. The company's primary offering is the Congo Red Dot (CRD) urine test, designed to confirm or rule out the presence of this serious pregnancy-related condition. Established in 2014 and based in Groton, Connecticut, GestVision focuses on providing point-of-care diagnostic solutions that improve maternal and fetal health outcomes. Preeclampsia poses significant risks, including seizures and mortality, making effective detection and management essential. The company seeks to enhance the safety of pregnancies by delivering innovative diagnostic tools that support healthcare providers in identifying and addressing this critical health issue.
ZetrOZ
Grant in 2014
ZetrOZ, LLC is a manufacturer based in Trumbull, Connecticut, specializing in advanced ultrasound technology. Founded in 2009, the company focuses on developing non-invasive medical devices aimed at tissue healing and pain relief for chronic musculoskeletal conditions. ZetrOZ offers a range of products, including the UltrOZ Elite therapeutic systems, wearable veterinary ultrasound systems, and high intensity focused ultrasound systems tailored for biomedical research and industrial applications. Their product lineup also features low-profile ultrasound transducers for therapeutic and diagnostic uses, as well as a variety of applications in industrial monitoring and aquatic environments. The company's innovative generator technology enhances efficiency, portability, and cost-effectiveness, making ultrasound systems more accessible for therapeutic uses such as wound care, surgical procedures, and aesthetic treatments.
IsoPlexis
Series A in 2014
IsoPlexis is a life science technology company based in Branford, Connecticut, founded in 2013. It focuses on developing a single-cell detection system that identifies patient immune responses at the single-cell level. This innovative platform enables the assessment of therapeutic safety and efficacy, as well as the monitoring of disease progression. IsoPlexis specializes in cell-based proteomic systems and biomarkers, providing insights into functional protein biology and cellular signaling networks with high resolution. By offering these capabilities, the company aids in predicting patient responses to novel immunotherapies and cellular therapies, ultimately enhancing therapeutic development and informing clinical decisions.
SmartPay Solutions
Series A in 2014
SmartPay Solutions LLC, founded in 2010 and based in Southington, Connecticut, specializes in providing a cloud-based software solution for pay-as-you-go workers’ compensation plans. The SmartPay platform is designed for insurance carriers, independent agents, and payroll providers, offering a flexible and user-friendly system that enables immediate access to essential services. The company's technology aims to streamline the workers' compensation process, ensuring that it meets the diverse needs of its clients. By leveraging innovative software, SmartPay Solutions enhances the efficiency and effectiveness of pay-as-you-go workers’ compensation administration.
P2 Science
Series A in 2014
P2 Science, Inc. is a bio-renewable chemistry company based in Woodbridge, Connecticut, specializing in the development and production of specialty chemicals derived from renewable feedstocks, such as vegetable oils. Founded in 2009 by a team that includes Yale scientists and an experienced chemical industry executive, the company focuses on creating high-value ingredients for flavors, fragrances, cosmetics, and other applications. P2 Science aims to provide sustainable alternatives to traditional petrochemical products, catering to diverse markets, including personal care, household cleaning, agriculture, and environmental remediation. Their innovative technology enables the conversion of renewable resources into cost-effective chemical solutions, addressing the increasing demand for greener options among major users in the specialty chemicals sector. The company also maintains a laboratory in New Haven, Connecticut, to support ongoing research and partnerships throughout the supply chain.
Avitus Orthopaedics
Seed Round in 2014
Avitus Orthopaedics, Inc. is a medical device company focused on developing and commercializing minimally invasive surgical devices specifically for autologous bone graft harvesting. The company’s flagship product, the Avitus bone harvester, is designed to efficiently harvest cancellous bone and marrow, aimed at enhancing clinical outcomes in orthopedic surgeries. Founded in 2011 and initially known as BOSS Medical, Inc., the company rebranded to Avitus Orthopaedics in March 2014. With its headquarters in Shelton, Connecticut, Avitus Orthopaedics combines technical expertise and clinical experience to create innovative instruments that not only improve surgical techniques but also aim to reduce healthcare costs for patients.
CashPath Financial
Seed Round in 2014
Cashpath Financial LLC, established in 2011 and located in Stamford, Connecticut, specializes in cash-flow management through its innovative mobile application. This app assists users in predicting their future cash flow, providing insights into daily, weekly, and monthly spending limits. By offering actionable guidance on saving and spending, Cashpath aims to foster financial success and help users manage their finances more effectively. The company is currently preparing to launch a beta version of its application, which is designed to enhance users' financial planning and promote positive cash flow.
GlyGenix Therapeutics
Seed Round in 2014
GlyGenix Therapeutics develops therapeutic products aimed at curing metabolic disorders, specifically focusing on the treatment of Glycogen Storage Disease type 1a (GSD1a). The company is involved in the manufacture and delivery of gene therapies designed to address this condition. Established in 2006 and headquartered in Woodbridge, Connecticut, GlyGenix Therapeutics collaborates with prominent institutions such as the National Institutes of Health, Duke University, the University of Florida, and Royal Philips Electronics to advance its research and therapeutic initiatives.
Eli Nutrition
Seed Round in 2014
Eli Nutrition, Inc. is a company based in New Haven, Connecticut, that specializes in the development of antacid products. Its primary offering is Tummyzen, a zinc-based over-the-counter acid reducer designed to provide relief from heartburn. Founded in 2013, Eli Nutrition focuses on addressing digestive health issues through its innovative product line.
BioRez
Venture Round in 2014
Biorez, Inc. is a medical device company specializing in the development of bioresorbable scaffold implants aimed at regenerating functional tissue in vivo. Founded in 2008 and based in New Haven, Connecticut, Biorez offers innovative products such as an off-the-shelf implant for anterior cruciate ligament (ACL) reconstruction, which eliminates the need for harvesting donor tissue and serves as a superior alternative to cadaver-based materials. The company's technology utilizes a degradable polymer, specifically PLLA, to create implants that stabilize surgical repairs and facilitate the body's natural tissue regeneration, thereby enhancing musculoskeletal outcomes. Among its product lineup is the L-C Ligament® and the biorez GRAFT™, an FDA-cleared device designed for soft tissue augmentation of the rotator cuff. By leveraging this technology, Biorez aims to accelerate patient recovery and improve surgical outcomes in orthopedic procedures.
CashPath Financial
Venture Round in 2013
Cashpath Financial LLC, established in 2011 and located in Stamford, Connecticut, specializes in cash-flow management through its innovative mobile application. This app assists users in predicting their future cash flow, providing insights into daily, weekly, and monthly spending limits. By offering actionable guidance on saving and spending, Cashpath aims to foster financial success and help users manage their finances more effectively. The company is currently preparing to launch a beta version of its application, which is designed to enhance users' financial planning and promote positive cash flow.
Precipio Diagnostics
Series B in 2013
Precipio is a cancer diagnostics reference laboratory, delivering the latest in advanced diagnostics and personalized medicine. Our goal is to assist oncologists in providing the best care for their patients. At the intersection of academia, cancer research, and diagnostics, we connect physicians with world-renown pathologists at the Yale School of Medicine. At Precipio, our customers and their patients benefit from the most accurate, expert diagnosis.
AxioMx
Venture Round in 2013
AxioMx Inc., founded in 2012 and headquartered in Branford, Connecticut, specializes in the discovery, development, and production of recombinant antibodies. The company offers a comprehensive suite of custom antibody services, including antigen design, antibody optimization, and production tailored to the needs of researchers in diagnostics, pharmaceuticals, biotechnology, and academia. AxioMx utilizes proprietary phage display libraries and advanced affinity maturation techniques to create high-affinity antibodies that can target challenging proteins, including phosphorylated and non-immunogenic targets. Additionally, the company provides services for converting antibody formats, such as scFv to IgG, and optimizing antibody frameworks. With a focus on enhancing binding affinities and producing consistent recombinant antibodies, AxioMx supports the development of essential tools for life science research and diagnostic applications. In 2015, AxioMx became a subsidiary of Abcam Plc, further expanding its capabilities in the antibody market.
Arvinas
Series A in 2013
Arvinas, Inc. is a clinical-stage biopharmaceutical company based in New Haven, Connecticut, that specializes in the discovery, development, and commercialization of innovative therapies aimed at degrading disease-causing proteins. The company's lead product candidates include ARV-110, a proteolysis targeting chimera (PROTAC) currently in phase I clinical trials for metastatic castration-resistant prostate cancer, and ARV-471, which targets the estrogen receptor for patients with metastatic ER-positive/HER2-negative breast cancer. In addition to these, Arvinas is developing various other PROTACs aimed at degrading clinically relevant androgen receptor mutations and treatments for neurodegenerative diseases, including tauopathies. The company has established collaborations with prominent pharmaceutical firms such as Pfizer Inc., Genentech, and Bayer AG, enhancing its research capabilities and reach within the biopharmaceutical landscape. Founded in 2015, Arvinas aims to improve patient outcomes by eliminating harmful proteins from the body through its proprietary technology.
American Oil Solutions
Seed Round in 2013
American Oil Solutions (AOS) is a green technology company located in Bridgeport, Connecticut, specializing in the recycling of used hydrocarbon products, particularly tires. The company utilizes a closed-loop, pollution-free process to convert old tires into valuable products such as fuel oil, carbon char, syngas, scrap steel, and specialty chemicals. AOS aims to establish itself as a leader in the hydrocarbon product recycling market, leveraging the abundant supply of tires to create multiple revenue streams and promote sustainable practices in waste management.
iCleanse
Seed Round in 2013
iCleanse, established in 2012, specializes in the manufacturing and distribution of multi-bay docking stations for secure storage, charging, and disinfection of mobile devices. Its flagship product, ReadyDock, is the world's first and only chemical-free disinfection docking station, designed to support workflow and overall management of mobile devices in various sectors such as hospitals, retail, food service, and education. The company's products are sold through resellers and are headquartered in Avon, Connecticut.
Logicbroker
Series A in 2013
Logicbroker, Inc. is a technology company specializing in cloud and supply chain automation solutions tailored for digital commerce. Founded in 2010 and headquartered in Shelton, Connecticut, Logicbroker provides advanced electronic data interchange (EDI) and drop ship technology that integrates brands, retailers, and their operational systems. The company's offerings include a comprehensive suite of tools for monitoring supply chain data, such as inventory management, acknowledgments, shipments, and invoices, alongside a robust Logicbroker Commerce API that streamlines communication between partners throughout the order lifecycle. With a network of over 4,000 brand suppliers and more than 140 certified retail and marketplace channels, Logicbroker facilitates significant online sales growth, driving over $2.2 billion annually for leading retailers. Its notable clients include well-known brands such as Kroger, Coca-Cola, and Unilever, and the company maintains a strategic partnership with Ingram Micro Commerce & Lifecycle Services to enhance its service offerings.
P2 Science
Seed Round in 2013
P2 Science, Inc. is a bio-renewable chemistry company based in Woodbridge, Connecticut, specializing in the development and production of specialty chemicals derived from renewable feedstocks, such as vegetable oils. Founded in 2009 by a team that includes Yale scientists and an experienced chemical industry executive, the company focuses on creating high-value ingredients for flavors, fragrances, cosmetics, and other applications. P2 Science aims to provide sustainable alternatives to traditional petrochemical products, catering to diverse markets, including personal care, household cleaning, agriculture, and environmental remediation. Their innovative technology enables the conversion of renewable resources into cost-effective chemical solutions, addressing the increasing demand for greener options among major users in the specialty chemicals sector. The company also maintains a laboratory in New Haven, Connecticut, to support ongoing research and partnerships throughout the supply chain.
eBrevia
Seed Round in 2013
eBrevia, Inc. specializes in artificial intelligence-driven software designed for legal applications, including due diligence, contract management, lease abstraction, and document drafting. The company's offerings include the Diligence Accelerator, which helps attorneys efficiently navigate the due diligence process by extracting relevant content from legal documents and populating summary templates. Additionally, the eBrevia Contract Analyzer aids organizations in storing, retrieving, and analyzing contracts, while the Lease Abstractor streamlines the lease review process by highlighting pertinent information. eBrevia Bespoke further enhances this by identifying custom terms within legal documents. Founded in 2011 and headquartered in Stamford, Connecticut, with additional offices in San Francisco and New York, eBrevia serves law firms and corporate legal departments. The company has received recognition for its innovative technology, including awards from the Connecticut Technology Council and accolades at national competitions. eBrevia operates as a subsidiary of Donnelley Financial Solutions, Inc.
Innovatient Solutions
Series A in 2013
Innovatient Solutions provides a patient engagement solution to the health care industry. They strive every day to enable patients to take more control of their health and to have more say in how they are cared for before, during, and after their hospital stay. It was founded in 2010 and headquartered in Farmington, Connecticut.
ZetrOZ
Series A in 2013
ZetrOZ, LLC is a manufacturer based in Trumbull, Connecticut, specializing in advanced ultrasound technology. Founded in 2009, the company focuses on developing non-invasive medical devices aimed at tissue healing and pain relief for chronic musculoskeletal conditions. ZetrOZ offers a range of products, including the UltrOZ Elite therapeutic systems, wearable veterinary ultrasound systems, and high intensity focused ultrasound systems tailored for biomedical research and industrial applications. Their product lineup also features low-profile ultrasound transducers for therapeutic and diagnostic uses, as well as a variety of applications in industrial monitoring and aquatic environments. The company's innovative generator technology enhances efficiency, portability, and cost-effectiveness, making ultrasound systems more accessible for therapeutic uses such as wound care, surgical procedures, and aesthetic treatments.
iCleanse
Seed Round in 2013
iCleanse, established in 2012, specializes in the manufacturing and distribution of multi-bay docking stations for secure storage, charging, and disinfection of mobile devices. Its flagship product, ReadyDock, is the world's first and only chemical-free disinfection docking station, designed to support workflow and overall management of mobile devices in various sectors such as hospitals, retail, food service, and education. The company's products are sold through resellers and are headquartered in Avon, Connecticut.
P2 Science
Seed Round in 2013
P2 Science, Inc. is a bio-renewable chemistry company based in Woodbridge, Connecticut, specializing in the development and production of specialty chemicals derived from renewable feedstocks, such as vegetable oils. Founded in 2009 by a team that includes Yale scientists and an experienced chemical industry executive, the company focuses on creating high-value ingredients for flavors, fragrances, cosmetics, and other applications. P2 Science aims to provide sustainable alternatives to traditional petrochemical products, catering to diverse markets, including personal care, household cleaning, agriculture, and environmental remediation. Their innovative technology enables the conversion of renewable resources into cost-effective chemical solutions, addressing the increasing demand for greener options among major users in the specialty chemicals sector. The company also maintains a laboratory in New Haven, Connecticut, to support ongoing research and partnerships throughout the supply chain.
NorthPage
Venture Round in 2013
NorthPage Inc. offers a cloud-based digital marketing optimization platform designed to assist enterprise marketing organizations in enhancing their digital performance. Founded in 2007 and headquartered in Southbury, Connecticut, the company provides tools for performance benchmarking, competitive analysis, and best-practice guidance across various digital channels. Its solutions focus on optimizing websites, e-commerce sites, mobile marketing, social media, search engine marketing, content marketing, and e-retail programs. NorthPage serves a diverse range of industries, including retail, financial services, consumer products, pharmaceuticals, and technology. The platform leverages cognitive marketing analytics and an algorithmic approach to provide actionable insights that help marketers improve customer journeys, user experiences, engagement, and conversion rates.
eBrevia
Seed Round in 2013
eBrevia, Inc. specializes in artificial intelligence-driven software designed for legal applications, including due diligence, contract management, lease abstraction, and document drafting. The company's offerings include the Diligence Accelerator, which helps attorneys efficiently navigate the due diligence process by extracting relevant content from legal documents and populating summary templates. Additionally, the eBrevia Contract Analyzer aids organizations in storing, retrieving, and analyzing contracts, while the Lease Abstractor streamlines the lease review process by highlighting pertinent information. eBrevia Bespoke further enhances this by identifying custom terms within legal documents. Founded in 2011 and headquartered in Stamford, Connecticut, with additional offices in San Francisco and New York, eBrevia serves law firms and corporate legal departments. The company has received recognition for its innovative technology, including awards from the Connecticut Technology Council and accolades at national competitions. eBrevia operates as a subsidiary of Donnelley Financial Solutions, Inc.
NXT-ID
Seed Round in 2013
Nxt-ID, Inc. is a technology company focused on developing and marketing innovative solutions for healthcare applications, payment systems, and the Internet of Things (IoT). Founded in 2011 and headquartered in Oxford, Connecticut, the company specializes in areas such as access control, biometric identity verification, security, encryption, and data protection. Through its subsidiary, LogicMark LLC, Nxt-ID manufactures and distributes both non-monitored and monitored personal emergency response systems, primarily targeting dealers, distributors, and the United States Department of Veterans Affairs. The company serves a diverse range of markets, including security, healthcare, financial technology, and IoT.
CyVek
Series D in 2013
CyVek, Inc. is a biotechnology company based in Wallingford, Connecticut, established in 2008. The company specializes in developing a technology platform designed for measuring analytes in biological samples. CyVek offers an integrated test system that features a microfluidic cartridge, enabling the analysis of multiple biomarkers from minimal quantities of biological materials. This innovative approach facilitates efficient and accurate testing, supporting advancements in diagnostics and research.
AxioMx
Venture Round in 2012
AxioMx Inc., founded in 2012 and headquartered in Branford, Connecticut, specializes in the discovery, development, and production of recombinant antibodies. The company offers a comprehensive suite of custom antibody services, including antigen design, antibody optimization, and production tailored to the needs of researchers in diagnostics, pharmaceuticals, biotechnology, and academia. AxioMx utilizes proprietary phage display libraries and advanced affinity maturation techniques to create high-affinity antibodies that can target challenging proteins, including phosphorylated and non-immunogenic targets. Additionally, the company provides services for converting antibody formats, such as scFv to IgG, and optimizing antibody frameworks. With a focus on enhancing binding affinities and producing consistent recombinant antibodies, AxioMx supports the development of essential tools for life science research and diagnostic applications. In 2015, AxioMx became a subsidiary of Abcam Plc, further expanding its capabilities in the antibody market.
deets
Series A in 2012
Deets, Inc. is a mobile technology company based in Westport, Connecticut, founded in 2011. It specializes in a mobile communication application for Android and iPhone users, which enables the creation of organized groups, private messaging, and profile customization. The application also features a dashboard that synchronizes contacts and facilitates group conversations and collaboration. Deets aims to enhance productivity and meaningful sharing among users by providing a secure platform that mitigates the presence of fake profiles. The company launched its first product in 2012, drawing on the expertise of its founders, who previously held leadership roles in successful online companies.
Innovatient Solutions
Debt Financing in 2012
Innovatient Solutions provides a patient engagement solution to the health care industry. They strive every day to enable patients to take more control of their health and to have more say in how they are cared for before, during, and after their hospital stay. It was founded in 2010 and headquartered in Farmington, Connecticut.
Lean Launch Ventures
Seed Round in 2012
Lean Launch Ventures (LLV), founded in 2012 and based in Weston, Connecticut, aimed to support entrepreneurs through an accelerator curriculum grounded in the Lean LaunchPad methodology developed by Steve Blank and Bob Dorf. The firm focused on mentoring and investing in early-stage startups while also advising larger enterprises on fostering innovation. LLV served as a platform for its principals to raise and manage capital for investments in companies participating in its acceleration initiatives. However, LLV ceased operations on December 31, 2018.
NovaTract Surgical
Series A in 2012
NovaTract Surgical, Inc. is a medical device company focused on enhancing minimally invasive surgical practices. Founded in 2010 and based in Connecticut, the company develops innovative solutions such as NovaGrasp, a single-use laparoscopic grasper for tissue and organ retraction, and NovaTract, a dynamic retractor for various minimally invasive surgeries, including colorectal, urologic, gynecologic, and robotic-assisted procedures. NovaTract Surgical aims to address the growing fields of single-incision laparoscopic surgery and natural orifice transluminal endoscopic surgery, providing advanced tools to improve surgical outcomes for healthcare institutions and surgeons.
BioRelix
Venture Round in 2012
BioRelix, Inc., a biopharmaceutical company, engages in the discovery and development of anti-biotic drug candidates for the treatment of infectious diseases in the United States. It develops a portfolio of riboswitch-based therapeutic agents to overcome the lethal and devastating causes of bacterial infections. The company was founded in 2005 and is based in New Haven, Connecticut.
eBrevia
Convertible Note in 2012
eBrevia, Inc. specializes in artificial intelligence-driven software designed for legal applications, including due diligence, contract management, lease abstraction, and document drafting. The company's offerings include the Diligence Accelerator, which helps attorneys efficiently navigate the due diligence process by extracting relevant content from legal documents and populating summary templates. Additionally, the eBrevia Contract Analyzer aids organizations in storing, retrieving, and analyzing contracts, while the Lease Abstractor streamlines the lease review process by highlighting pertinent information. eBrevia Bespoke further enhances this by identifying custom terms within legal documents. Founded in 2011 and headquartered in Stamford, Connecticut, with additional offices in San Francisco and New York, eBrevia serves law firms and corporate legal departments. The company has received recognition for its innovative technology, including awards from the Connecticut Technology Council and accolades at national competitions. eBrevia operates as a subsidiary of Donnelley Financial Solutions, Inc.
Umbie Health
Debt Financing in 2012
Umbie Health Corporation, an East Hartford, Conn.-based that develops a Web-based and mobile practice management application for dentists.
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