Malin Corporation

Malin Corporation plc is an Irish public limited company established in 2015, with its headquarters in Dublin and additional offices in New Haven, Connecticut, and Research Triangle, North Carolina. The company specializes in venture capital investments, focusing on innovative enterprises within the life sciences and healthcare technology sectors, particularly in oncology, immunology, and genetic diseases. Malin's strategy involves the selective application of capital and operational expertise to support private, pre-IPO, and pre-trade sale businesses in rapidly growing markets. By actively engaging with its investee companies, Malin aims to enhance their value propositions and facilitate their journey toward commercial success.

Adrian Howd

CEO

17 past transactions

CG Oncology

Series F in 2023
CG Oncology, formerly known as Cold Genesys, is a privately held clinical-stage biopharmaceutical company specializing in the development of innovative oncolytic immunotherapies aimed at treating cancer. The company focuses on creating therapies that offer alternatives to conventional cancer treatments, particularly for patients with bladder cancer. Its lead candidate, cretostimogene grenadenorepvec, is a targeted intravesical immunotherapy agent designed to be delivered directly to the bladder. Currently, CG Oncology is conducting multiple clinical trials, including two phase three trials addressing high-risk and intermediate-risk non-muscle invasive bladder cancer (NMIBC), as well as a phase two study in combination with a checkpoint inhibitor for high-risk NMIBC. Through its research and clinical endeavors, CG Oncology aims to provide effective and less invasive treatment options for bladder cancer patients.

CG Oncology

Series E in 2022
CG Oncology, formerly known as Cold Genesys, is a privately held clinical-stage biopharmaceutical company specializing in the development of innovative oncolytic immunotherapies aimed at treating cancer. The company focuses on creating therapies that offer alternatives to conventional cancer treatments, particularly for patients with bladder cancer. Its lead candidate, cretostimogene grenadenorepvec, is a targeted intravesical immunotherapy agent designed to be delivered directly to the bladder. Currently, CG Oncology is conducting multiple clinical trials, including two phase three trials addressing high-risk and intermediate-risk non-muscle invasive bladder cancer (NMIBC), as well as a phase two study in combination with a checkpoint inhibitor for high-risk NMIBC. Through its research and clinical endeavors, CG Oncology aims to provide effective and less invasive treatment options for bladder cancer patients.

Poseida Therapeutics

Series C in 2019
Poseida Therapeutics, Inc. is a clinical-stage biopharmaceutical company based in San Diego, California, dedicated to developing innovative therapeutics for patients with significant unmet medical needs. The company specializes in genome engineering technologies and is focused on creating targeted treatments, including a pipeline of autologous and allogeneic chimeric antigen receptor T cell (CAR-T) therapies aimed at addressing hematological malignancies and solid tumors. Additionally, Poseida is advancing gene therapies for rare and life-threatening diseases, such as Ornithine transcarbamylase deficiency and methylmalonic acidemia, along with therapies for genetic liver diseases. Founded in 2014, Poseida Therapeutics is committed to improving patient outcomes through its cutting-edge research and development efforts.

Poseida Therapeutics

Series B in 2018
Poseida Therapeutics, Inc. is a clinical-stage biopharmaceutical company based in San Diego, California, dedicated to developing innovative therapeutics for patients with significant unmet medical needs. The company specializes in genome engineering technologies and is focused on creating targeted treatments, including a pipeline of autologous and allogeneic chimeric antigen receptor T cell (CAR-T) therapies aimed at addressing hematological malignancies and solid tumors. Additionally, Poseida is advancing gene therapies for rare and life-threatening diseases, such as Ornithine transcarbamylase deficiency and methylmalonic acidemia, along with therapies for genetic liver diseases. Founded in 2014, Poseida Therapeutics is committed to improving patient outcomes through its cutting-edge research and development efforts.

Poseida Therapeutics

Series A in 2017
Poseida Therapeutics, Inc. is a clinical-stage biopharmaceutical company based in San Diego, California, dedicated to developing innovative therapeutics for patients with significant unmet medical needs. The company specializes in genome engineering technologies and is focused on creating targeted treatments, including a pipeline of autologous and allogeneic chimeric antigen receptor T cell (CAR-T) therapies aimed at addressing hematological malignancies and solid tumors. Additionally, Poseida is advancing gene therapies for rare and life-threatening diseases, such as Ornithine transcarbamylase deficiency and methylmalonic acidemia, along with therapies for genetic liver diseases. Founded in 2014, Poseida Therapeutics is committed to improving patient outcomes through its cutting-edge research and development efforts.

Xenex

Venture Round in 2017
Xenex is a company dedicated to reducing healthcare-associated infections (HAIs) through its innovative disinfection technology. Founded in 2009 and headquartered in San Antonio, Texas, Xenex develops a portable ultraviolet room disinfection system that employs pulsed xenon UV light to effectively eliminate harmful microorganisms, including bacteria and viruses, in healthcare environments. Since its commercial introduction in 2010, Xenex's devices have been integrated into infection control protocols in nearly three hundred hospitals across the United States. The company's mission focuses on saving lives and alleviating suffering by significantly lowering the bacterial load that contributes to the risk of HAIs, thereby protecting patients, healthcare staff, and the financial health of medical facilities.

Artizan Biosciences

Venture Round in 2017
Artizan Biosciences, Inc. is a biotechnology company focused on developing small molecule drugs for human use, particularly targeting diseases linked to intestinal inflammation. Founded in 2016 and headquartered in New Haven, Connecticut, the company employs its proprietary IgA-SEQ technology platform to identify and characterize disease-driving bacteria within the intestinal microbiota. This innovative approach aims to create precision therapeutics that address the root causes of various serious conditions, including digestive disorders, obesity, autoimmune diseases, and a range of other health issues affecting the skin, lungs, and central nervous system. By focusing on unmet medical needs, Artizan Biosciences seeks to provide novel treatment options for patients.

Wren Therapeutics

Funding Round in 2017
Wren Therapeutics Limited is a biopharmaceutical company based in Cambridge, United Kingdom, established in 2016. The company focuses on drug discovery and development for various protein misfolding diseases, which encompass neurological disorders such as Alzheimer's and Parkinson's diseases, as well as type-2 diabetes and several rare forms of amyloidosis. Wren Therapeutics leverages a proprietary technology platform that stems from extensive scientific research conducted at the University of Cambridge and Lund University. This platform enables Wren to develop small molecule therapeutics aimed at addressing the underlying mechanisms of these complex diseases.

Cilatus BioPharma

Acquisition in 2017
Cilatus BioPharma AG is a consulting firm based in Sarnen, Switzerland, specializing in comprehensive services for biopharma technical operations. Founded in 2014, the company supports small, medium, and large biopharma organizations by offering expertise in CMC (Chemistry, Manufacturing, and Controls) development, regulatory affairs, quality management, and engineering. Cilatus provides end-to-end solutions that include strategy development and execution, project management, and operational oversight of both drug substance and drug product manufacturing. Key services encompass technical CMC development from the discovery phase through to commercial manufacturing, as well as the management of contract development and manufacturing organizations (CDMO and CMO). Additionally, Cilatus offers quality assurance management, vendor auditing, and regulatory affairs services, ensuring compliance with industry standards. The firm’s integrated team of experienced consultants focuses on delivering tailored solutions to enhance the efficiency and effectiveness of biopharma operations.

Kymab

Series C in 2016
Kymab Limited is a clinical-stage biopharmaceutical company based in Cambridge, United Kingdom, specializing in the discovery and development of fully human monoclonal antibody therapeutics. Founded in 2009, Kymab utilizes its proprietary Kymouse and IntelliSelect platforms to develop therapies targeting challenging and novel drug targets within immuno-oncology and immune-mediated diseases. The company's comprehensive antibody platforms are designed to maximize the diversity of human antibodies, enabling the creation of novel therapeutic options for conditions such as cancer and autoimmune diseases. Kymab has established strategic collaborations with Heptares Therapeutics and LifeArc to advance its research and development efforts. As a subsidiary of Kymab Group Limited, the company is focused on addressing unmet medical needs through innovative antibody-based therapies.

Poseida Therapeutics

Series A in 2015
Poseida Therapeutics, Inc. is a clinical-stage biopharmaceutical company based in San Diego, California, dedicated to developing innovative therapeutics for patients with significant unmet medical needs. The company specializes in genome engineering technologies and is focused on creating targeted treatments, including a pipeline of autologous and allogeneic chimeric antigen receptor T cell (CAR-T) therapies aimed at addressing hematological malignancies and solid tumors. Additionally, Poseida is advancing gene therapies for rare and life-threatening diseases, such as Ornithine transcarbamylase deficiency and methylmalonic acidemia, along with therapies for genetic liver diseases. Founded in 2014, Poseida Therapeutics is committed to improving patient outcomes through its cutting-edge research and development efforts.

3D4Medical.com

Venture Round in 2015
3D4Medical Limited is a technology company focused on developing medical, educational, and health and fitness applications for various platforms, including iOS, Android, and Windows. Founded in 2004 and based in Dublin, Ireland, the company creates a range of apps designed to aid professional reference, student learning, and patient education. Their notable products include Essential Anatomy 2, Essential Skeleton, and iMuscle, among others. 3D4Medical also specializes in producing high-quality 3D medical images and animations, which are utilized by major publications worldwide. The company's innovative platform covers various aspects of human anatomy, muscle movement, and interactive radiology, allowing users to explore anatomical details in a 3D environment. As of late 2019, 3D4Medical operates as a subsidiary of Elsevier B.V.

Altan Pharma

Acquisition in 2015
Altan Pharma is a specialty pharmaceutical company focused on the development, manufacturing, and marketing of injectable medicines specifically for hospital use. The company offers a diverse range of medical products in injectable forms, including flexible plastic bags, liquid vials, lyophilized vials, and ampoules. Altan Pharma's product portfolio addresses various medical needs, providing medications utilized in pain management, anesthesia, epilepsy treatment, oncology, anti-infectives, cardiovascular care, and gynecology. Through its comprehensive offerings, Altan Pharma aims to support healthcare providers in delivering effective treatments to patients in critical care settings.

Melinta Therapeutics

Post in 2015
Melinta Therapeutics, Inc. is a commercial-stage pharmaceutical company based in Morristown, New Jersey, specializing in the discovery, development, and commercialization of anti-infective therapies for bacterial infections in North America. The company offers a range of antibiotics, including Baxdela, Vabomere, Orbactiv, and Minocin, targeting various serious bacterial infections such as acute bacterial skin and skin structure infections (ABSSSIs) and gram-negative infections. Melinta is actively advancing its investigational antibiotic, delafloxacin, which is currently in Phase 3 development for ABSSSIs. Additionally, the company is engaged in research to develop new classes of antibiotics aimed at combating drug-resistant pathogens, particularly the ESKAPE group responsible for many hospital-acquired infections. Through its innovative approaches, Melinta Therapeutics addresses the urgent need for new therapies against drug-resistant infections, a critical public health challenge today.

Kymab

Series B in 2015
Kymab Limited is a clinical-stage biopharmaceutical company based in Cambridge, United Kingdom, specializing in the discovery and development of fully human monoclonal antibody therapeutics. Founded in 2009, Kymab utilizes its proprietary Kymouse and IntelliSelect platforms to develop therapies targeting challenging and novel drug targets within immuno-oncology and immune-mediated diseases. The company's comprehensive antibody platforms are designed to maximize the diversity of human antibodies, enabling the creation of novel therapeutic options for conditions such as cancer and autoimmune diseases. Kymab has established strategic collaborations with Heptares Therapeutics and LifeArc to advance its research and development efforts. As a subsidiary of Kymab Group Limited, the company is focused on addressing unmet medical needs through innovative antibody-based therapies.

Novan

Private Equity Round in 2015
Novan, Inc. is a clinical development-stage biotechnology company headquartered in Morrisville, North Carolina, focused on creating nitric oxide-based therapies for dermatological and oncovirus-mediated diseases. The company is engaged in the development of several clinical-stage dermatology product candidates, including SB204, a topical treatment for acne vulgaris; SB206, an anti-viral gel for viral skin infections; SB208, a broad-spectrum anti-fungal gel for skin and nail infections; and SB414, a topical cream for inflammatory skin diseases. Additionally, Novan is developing SB207, another topical anti-viral product candidate. By utilizing a proprietary technology platform that encapsulates nitric oxide in nano-particles, Novan aims to deliver therapeutic agents precisely to targeted areas in the body. Established in 2006, the company collaborates with strategic partners to advance its innovative therapies addressing unmet medical needs.

Serenus Biotherapeutics

Venture Round in 2015
Serenus Biotherapeutics is a privately held specialty biopharmaceutical company focused on the late-stage development and commercialization of therapies aimed at addressing critical diseases. The company engages in in-licensing and registering drugs that have received approval in the United States, Europe, and Japan, specifically targeting unmet medical needs with high prevalence in the African market. Through its efforts, Serenus Biotherapeutics aims to provide effective treatment options for patients in regions where such therapies are urgently required.
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