Founded in 2000, General Catalyst is a venture capital firm specializing in early-stage and growth equity investments. It focuses on accelerating ideas, careers, and companies towards success by providing ongoing momentum and mentorship based on deep experience.

SOSV is a global venture capital firm that supports early-stage startups through active, founder-first development programs. Its flagship initiatives HAX and IndieBio provide facilities, engineering resources, services, and laboratory equipment to accelerate product development and prepare companies for subsequent funding rounds. SOSV focuses on deep technology across health, environmental, and cross-border software sectors, aiming to solve human and planetary health challenges. In addition to providing capital, the firm emphasizes intensive programmatic support to help portfolio companies move quickly from seed toward growth, including customer acquisition and scale. The firm operates globally with a bias toward startups targeting rapid international expansion, especially in Asia, and tends to back a small cohort of high-potential companies to accelerate their progress and attract leading investors.

Founded in 1989, OrbiMed is a New York-based healthcare-dedicated investment firm managing approximately $5 billion in assets. It invests across the spectrum of healthcare companies, from private start-ups to large multinational corporations, focusing on biopharmaceuticals, life sciences, digital health, medical devices, and diagnostics sectors globally.

Alumni Ventures Group is a venture capital firm based in Manchester, New Hampshire, with offices across North America. It provides access to venture investing for individual accredited investors, particularly alumni networks, by offering diversified portfolios of venture opportunities and allowing members to invest alongside fellow alumni in ventures led by peers. The firm backs early-stage and later-stage opportunities across technology, consumer, healthcare, financial services, and other sectors, with a sector- and geography-agnostic approach. It typically invests between $10,000 and $3 million per deal and emphasizes the involvement of alumni connections and an institutional lead investor in opportunities. Alumni Ventures also offers focused funds to broaden participation, enabling accredited investors to access venture portfolios diversified by type, sector, stage, and geography. The model aims to democratize access to venture capital while maintaining rigorous selection standards through alumni networks.

Founded in Boston in 2004, RA Capital is an investment firm specializing in life sciences and drug development. Its team, with backgrounds in biology, chemistry, medicine, and industry experience, invests in early-stage companies with promising technologies and products across healthcare and life science sectors.

New Enterprise Associates is a venture capital firm founded in 1977 and based in Menlo Park, California, with offices in the United States, India and China. It makes investments across technology and healthcare startups at multiple stages, from seed to growth, including software, cloud, data, internet services, fintech, AI, e-commerce, and enterprise technology, as well as healthcare information technology, life sciences, medical devices, and biopharma. It also considers energy technology and infrastructure opportunities, such as solar, batteries and smart grids. The firm pursues a global approach, with activity in the United States, Asia and other regions, and supports companies through rounds of financing ranging from small to sizable investments as they scale. NEA focuses on building portfolios in software, IT services, consumer technology, and healthcare technology, backing ambitious entrepreneurs across sectors and geographies.

Khosla Ventures is a California-based venture capital firm founded in 2004 by Vinod Khosla. It provides capital and strategic guidance to startups across stages, focusing on technology-driven companies in areas such as artificial intelligence, climate and sustainability, enterprise software and services, fintech, digital health, medical technology and diagnostics, therapeutics, consumer products, and frontier technologies. The firm backs bold ventures with the potential to disrupt markets and improve lives, supporting companies from early to growth stages and working closely with entrepreneurs to apply science, technology and innovative business models. While primarily investing in North American technology companies, Khosla Ventures pursues opportunities globally and emphasizes experimentation and impact alongside financial returns. The firm also maintains related impact initiatives that support entrepreneurs addressing socio-economic challenges in emerging markets.

Andreessen Horowitz is a venture capital firm founded in 2009 by Marc Andreessen and Ben Horowitz and based in Menlo Park, California. It funds startups across the entire lifecycle, from seed to growth, with a broad focus on software and technology-enabled businesses. The firm backs companies in software, cloud infrastructure, digital platforms, data storage, and mobile and Internet services, as well as sectors at the intersection of technology with life sciences, such as bio healthcare and computational medicine. Its investments span artificial intelligence, fintech, consumer and enterprise software, crypto and blockchain, cybersecurity, and related infrastructure. Through strategic guidance and a hands-on approach, the firm aims to help portfolio companies scale and innovate.

Eli Lilly and Company is a global pharmaceutical leader engaged in the discovery, development, manufacture, and sale of medicines. It operates facilities in the United States, Puerto Rico, and many other countries, with products sold in about 135 countries. The company focuses on therapies in neuroscience, cardiometabolic, cancer, and immunology, and also conducts research in animal health and animal agriculture. Lilly supports patient outcomes and education through a philanthropic foundation that funds programs in underserved communities, including STEM education in Indianapolis.

Right Side Capital Management is a San Francisco based venture capital firm that backs early-stage technology startups with a focus on pre-seed rounds. It makes about 75-100 investments per year in capital-efficient companies seeking to reach product-market fit, typically in rounds of 50k to 500k and pre-money valuations of 1M to 3M. The firm pursues opportunities outside the San Francisco Bay Area and New York City, and it invests across the United States, Canada, Israel, Australia, New Zealand, and Western Europe, with a portfolio spanning many states and roughly two hundred prior investments since its early operations.

Qiming Venture Partners is a China-based venture capital firm founded in 2006, with offices in Shanghai, Beijing, Suzhou, Hong Kong and Singapore, and a global arm through Qiming Venture Partners USA. It manages multiple funds and invests in early and growth-stage companies across technology, information technology, healthcare, new consumer sectors, AI, robotics, semiconductors, software and digital health. The firm emphasizes a hands-on approach, often taking board seats and providing operational guidance to help CEOs scale and reach exits. Through its investments, it has backed hundreds of companies and supported numerous IPOs and M&A outcomes, with unicorns among its portfolio, illustrating breadth and depth across China and international markets.

Polaris Partners is a venture capital firm based in Boston, Massachusetts, with offices in San Francisco. Founded in 1996, it targets investments in technology and life science companies across the United States and Europe, supporting startups from early formation to profitable growth. The firm's healthcare and biotechnology focus encompasses digital health, consumer-centric care delivery, patient-provider solutions, data science and analytics, as well as therapeutics, genomics and other life science platforms. It backs companies across business-to-business and business-to-consumer models, software as a service, healthcare information technology and health tech sectors, partnering with repeat entrepreneurs to build durable, scale-ready businesses.

Founded in 2011, StartUp Health is dedicated to improving global health through collaboration with entrepreneurs. It invests in 'Health Transformers' across six continents, focusing on various health moonshots such as Access to Care, Cure Disease, and Mental Health. With over 330 companies in its portfolio, it's backed by prominent investors.

Founded in 2009 and based in New York City, BoxGroup is an early-stage investment fund focusing on pre-seed to Series A rounds. It invests globally, with a primary focus on New York City, Silicon Valley, and Los Angeles. The firm typically allocates between $50,000 and $250,000 per investment across various sectors including consumer, enterprise, fintech, healthcare, life science, marketplace, synthetic biology, and climate.

Venrock is a Palo Alto-based venture capital firm founded in 1969 as the venture capital arm of the Rockefeller family. It concentrates on seed and early-stage investments in technology and healthcare, with interests spanning information technology, life sciences and related sectors in the United States. The firm has supported a broad portfolio of companies, including Apple, Intel, Illumina, DoubleClick, Athenahealth, Gilead Sciences, Nest, SlideShare and Tudou. Venrock emphasizes long-term partnerships with entrepreneurs, combining hands-on venture support with rigorous data analysis to help startups grow into enduring companies.

Maverick Capital is a global investment firm with offices in New York, San Francisco, London, Hong Kong, Philadelphia, and Dallas. The firm seeks to grow and preserve capital through long/short hedged equity strategies and has extended its reach by backing private companies that represent disruptive business models or technologies. In addition to its main investment activities, Maverick Capital operates Maverick Ventures, its venture arm, which supports entrepreneurs from seed to growth stages, with a focus on healthcare, software and deep technology. The team generally leads rounds, takes board seats, and collaborates with management to build successful enterprises.

Founded in Singapore in 2017, Antler is an early-stage venture capital firm that invests globally. It focuses on backing exceptional founders from day one, offering a global community network of co-founders, talent, advisors, expansion support, and capital across various sectors such as technology, healthcare, finance, consumer goods, and more.

Novo Holdings is a Danish holding and investment firm managing the assets of the Novo Nordisk Foundation. Established in 1999, it invests globally in life science companies at all stages of development, with a portfolio also including equities, bonds, real estate, and infrastructure.

Oak HC/FT is a venture and growth equity investment firm specializing in healthcare information services and financial technology. It supports portfolio companies with strategic counsel, board-level participation, and access to a broad network of industry leaders to drive transformation in these sectors. The firm, based in Stamford, Connecticut, operates within the Oak Investment Partners family, leveraging sector-specific expertise from Oak's healthcare and fintech teams to build and scale innovative businesses.

8VC is a technology and life sciences investment firm that partners with founders to develop transformational technologies and create long-term value. Its activities span sectors such as healthcare, logistics, software, energy, manufacturing, enterprise IT, and life sciences, with a focus on supporting early-stage and growth opportunities in the United States and beyond.

Deerfield Management is a New York-based investment firm established in 1994 that focuses on healthcare. It operates across investment, information, and philanthropy to support the healthcare ecosystem. The firm provides private and public investments and offers long-term, structured capital to both public and private healthcare companies. Its portfolio spans life sciences, medical devices, diagnostics, digital health, and health services. As an investment adviser, it seeks opportunities in healthcare products and services and aims to accelerate innovation by combining capital with industry insight.

Versant Ventures is a healthcare-focused venture capital firm founded in 1999 and based in San Francisco, with offices in Canada, the United States, and Europe. The firm invests across the healthcare sector at all stages of company development, with emphasis on discovery and development of novel therapeutics. It leverages deep investment, operating, and scientific expertise to take a hands-on approach to building companies. Since its inception, more than 65 portfolio companies have achieved successful acquisitions or IPOs, reflecting its track record of helping startups advance therapies, devices, and life sciences ventures. The firm focuses on medical devices, biotechnology, pharmaceuticals, and life sciences, including oncology. It aims to support early-stage and growth-stage companies across the United States, Canada, and Europe, enabling development across the healthcare continuum.

Founded in 2014, Gaingels is a venture investment syndicate dedicated to supporting the LGBT+ community. It invests globally in companies led by LGBT+ founders or C-suite executives at all stages of growth, focusing on inclusivity and positive social change.

Bossa Invest is a venture capital firm based in Sao Paulo, Brazil, founded in 2011, that manages investment portfolios and provides asset management services to clients across sectors, with a focus on software as a service companies, and analyzes market trends to inform its investment decisions while operating in finance, technology, and real estate.

Founded in 2015, FJ Labs is a New York-based venture capital firm focusing on stage-agnostic investments in marketplaces and consumer-facing startups. Their investment range varies from $50,000 to $5,000,000, typically at seed or series A stages.

Founded in 2000, Lux Capital is a venture capital firm based in New York and Silicon Valley. It manages over $5 billion in assets, focusing on seed to growth investments at the intersection of technology and sciences. Lux actively supports entrepreneurs building successful businesses in high-growth sectors such as biochemistry, material science, electronics, infrastructure, aerospace, genomics, synthetic biology, and robotics.

Frist Cressey Ventures is a venture capital firm headquartered in Nashville, Tennessee, focused on early- and growth-stage investments in healthcare and digital health technologies and services. It seeks opportunities that improve quality of care, system integration, patient outcomes, and population health, partnering with entrepreneurs to accelerate growth and translate viable solutions into practical healthcare improvements. The firm targets technology-enabled healthcare enterprises and service businesses with strong potential to advance care delivery and health outcomes, and it emphasizes value-added collaboration with portfolio companies.

Established in 2020, the European Innovation Council supports innovative startups and researchers with promising ideas, focusing on early-stage companies with positive environmental, social, or governance impacts. It co-invests alongside private investors.

Founded in 1986, ARCH Venture Partners is a venture capital firm specializing in investments that bring innovations in life sciences to market. It focuses on companies co-founded by scientists and entrepreneurs, with a strong track record in commercializing technologies from academic research institutions and national laboratories.

Founded in 2018, Town Hall Ventures is a New York-based investment firm dedicated to transforming the U.S. healthcare market through technology. It invests in and supports visionary entrepreneurs focused on improving care delivery and health outcomes for underserved populations.

F-Prime Capital is a venture capital firm based in Cambridge, Massachusetts, affiliated with Fidelity Investments. It backs technology and life sciences entrepreneurs across the Americas, Europe, and Asia, drawing on Fidelity’s experience in funding early-stage companies. The firm focuses on sectors such as healthcare IT, medtech, therapeutics, fintech, frontier technologies, crypto, and broader information technology and technology-enabled services. With a global network of regional teams and affiliated funds, F-Prime provides domain expertise, strategic guidance, and industry connections to help founders build durable companies. It operates with a long-term, founder-centric approach, emphasizing value creation rather than external fundraising pressures.

Casdin Capital is a New York‑based investment firm founded in 2012 by Eli Casdin. The firm specializes in fundamental research and long‑short equity strategies focused on the life sciences and healthcare sectors, including oncology, digital health, and agtech. In addition to its public‑market fund, Casdin Capital invests in early‑stage to late‑stage private companies within these industries. It operates as a Registered Investment Adviser and, as of October 2020, managed approximately $2.2 billion in assets.

Echo Health Ventures is a venture capital firm that invests in healthcare companies, health technology, insurance technology and digital health in the United States. Based in Seattle with offices in Durham and Portland, the firm is stage-agnostic and aims to accelerate healthcare innovations to scale nationally by offering strategic guidance in addition to capital. Echo Health Ventures focuses on building deep, high-value relationships with portfolio companies to support growth and clinical impact, partnering with startups to advance patient care, improve care delivery, and broaden access to digital health tools.

First Round Capital is a San Francisco-headquartered seed-stage venture capital firm that backs technology startups from pre-seed through Series A. Since its founding in 2004, it has sought to build a vibrant community of entrepreneurs and support portfolio companies beyond capital through a suite of services, custom software, and in-person programs. The firm invests nationally and maintains offices in San Francisco and New York, often taking an active role in its companies. Typical initial investments are around $500,000, and it targets opportunities across enterprise, fintech, healthcare, consumer, hardware, artificial intelligence, and web3 sectors. First Round emphasizes founder support and inclusive practices, including initiatives such as the Diversity Term Sheet Rider.

Norwest Venture Partners is a venture capital and growth equity firm founded in 1961 and headquartered in California, with a presence in Menlo Park and Palo Alto. It backs technology-driven companies across stages, from seed to growth, primarily in the United States, with extensions into India and Israel. The firm invests in sectors including software, information services, business services, financial services, healthcare, enterprise technology, and consumer products and services. Norwest emphasizes a proactive, partnership-based approach, leveraging its extensive network, operating experience, and a broad range of resources to help CEOs and founders scale their businesses. Across its portfolio, Norwest has supported hundreds of companies through multiple rounds of financing, aiming to partner with teams that demonstrate strong market position, revenue traction, and durable growth potential. The firm seeks to combine capital with strategic guidance, enabling portfolio companies to accelerate product development, go-to-market execution, and international expansion where appropriate.

Founded in 2013, Susa Ventures is a venture capital firm based in San Francisco. It invests primarily in early-stage technology companies across sectors such as software, fintech, health, commerce, and education. The firm focuses on investments in Los Angeles, San Francisco, New York, and the Bay Area.

Invus Financial Advisors, LLC is an employee-owned investment firm based in New York, founded in 2006. The firm specializes in private equity investments and manages pooled investment vehicles, including hedge funds and funds of funds. Invus focuses on making direct and indirect investments in special situations, venture capital, and growth equity stages, with an emphasis on smaller companies and opportunistic co-investments. The firm adopts a flexible approach, recognizing the uniqueness of each company and the complexities of business transformation. Invus maintains a long-term commitment to its investments, aligning its incentives with those of its partners. With a history of empowering owner-managers since 1985 and a strong backing from a group of European families, Invus Financial Advisors manages over $4 billion in an evergreen fund and operates additional offices in London, Paris, and Hong Kong.

Founded in 2015, Flare Capital Partners is a Boston-based venture capital firm specializing in early-stage investments in healthcare technology. The firm focuses on transformational technologies and services that enable value-based healthcare, with an interest in medical devices, biopharmaceuticals, diagnostics, predictive medicine, data-centric devices, healthcare software, services, and digital health.

Optum is a healthcare services and innovation company dedicated to improving health outcomes. It offers a range of services including family medicine, mental health care, and specialized therapies for rare diseases. Optum also provides healthcare financial services and technology solutions to health plan providers.

IP Group is a London-based corporate firm that provides financial, strategic, and commercial expertise to clients internationally. Founded in 2001, the company focuses on creating value through the commercialisation of intellectual property derived from research-intensive institutions. It manages the end-to-end process of identifying viable IP, developing or partnering to build value, and establishing commercial arrangements that translate scientific advances into practical products and businesses. IP Group combines industry insight and financial experience to support science- and technology-based ventures, offering capital as well as strategic guidance to help companies grow and accelerate the impact of research. Its work spans clean technology, life sciences, and other deep technology sectors, with a track record of backing and developing ventures that aim to deliver tangible societal and economic outcomes.

Blue Venture Fund is the corporate venture capital arm of the BlueCross and BlueShield Association, based in Chicago. It operates as a strategic investor in healthcare, backing emerging companies in healthcare technology, healthcare services, and clinical sciences. The organization targets innovations that improve quality of care, enhance patient experience, and reduce costs, aligning with the needs of BCBS member companies and their policyholders. By funding early to growth-stage ventures, it supports the adoption of new solutions within the healthcare system and complements BCBS efforts to advance value-based care.

Founders Fund is a San Francisco-based venture capital firm that backs science and technology companies across multiple stages, from seed to late-stage. It pursues transformative technologies and follows a founder-friendly investment approach that provides substantial support with minimal interference. The firm invests in ventures solving difficult problems across sectors such as aerospace and transportation, artificial intelligence, advanced computing, energy, healthcare, biotechnology, cybersecurity, fintech, consumer internet, software, robotics, and related technology fields. It has backed notable companies early, including SpaceX, Palantir, and Facebook, reflecting a history of partnering with ambitious founders to scale breakthrough technologies.

Thrive Capital is a New York–based venture capital firm founded in 2009 that focuses on building and investing in internet, software, and technology-enabled companies. The firm provides venture-building services, operates as a registered investment adviser, and backs both early-stage and growth opportunities in software, media, and TMT sectors. Its investments span the United States and regions such as South America, with the aim of helping portfolio companies scale through capital and strategic guidance. Thrive Capital seeks long-term partnerships with entrepreneurs, leveraging its experience in the internet and software ecosystems to support product development, market expansion, and operational scaling.

Bessemer Venture Partners is a long-established venture capital firm based in Redwood City, California, founded in 1911. The firm makes early-stage and growth investments across software, cloud, fintech, cybersecurity, artificial intelligence, biotech, healthcare, consumer services, marketplaces and other technology sectors, with global reach in the United States, Israel, Canada and India. It supports founders from seed to scale, providing strategic guidance and capital to build durable businesses. The firm has backed notable companies such as Pinterest, LinkedIn, Shopify, Yelp, Twilio, DocuSign and Wix, among others, reflecting a history of funding transformative technology companies. Bessemer Venture Partners operates as a registered investment adviser and pursues opportunities across information technology, hardware and services worldwide.

Vivo Capital is a global healthcare investment firm based in Palo Alto with offices in Asia. Founded in 1996, it focuses on investing in and building high-quality companies in the United States and China. The firm engages across multiple strategies, including growth equity, private equity (buyouts), venture capital, and public equity, and invests in biopharmaceuticals, medical devices, and healthcare services. With about 25 years of operation, it manages approximately 5.8 billion in assets and has participated in over 290 public and private companies worldwide. The team comprises physicians, scientists, entrepreneurs, operating executives, and industry experts, reflecting a hands-on approach to helping portfolio companies scale in major healthcare markets.

Ben Franklin Technology Partners of Southeastern Pennsylvania is a technology-focused capital provider based in Philadelphia, founded in 1982 to advance the region's technology community. The organization funds and supports technology companies across Pennsylvania, especially in information technology, health, and physical sciences, investing substantial capital in early-stage and established ventures. It has invested over 170 million dollars in more than 1,750 regional technology companies and has launched university-industry partnerships to translate scientific discoveries into commercial products, while seeding regional initiatives that strengthen the entrepreneurial ecosystem and create jobs.

Everywhere Ventures is a New York-based venture capital firm focused on early-stage, pre-seed investments. Founded by founders for founders, it operates as a community-powered investing platform that unites capital, expertise, and mentoring from a broad network of founders and operators across ten micro funds. The firm supports global startups in their first financing rounds, with a focus on purpose-driven teams across money, health, and work verticals. Its model combines hands-on guidance from experienced builders with early-stage funding to help entrepreneurs build durable companies.

Liquid 2 Ventures is a San Francisco-based venture capital firm founded in 2015 that provides seed- and early-stage capital to technology startups. The firm supports founders across technology sectors and seeks to partner with ambitious teams developing innovative software and related technologies.

City Light Capital is a New York-based venture capital firm founded in 2004 that invests in seed, early, and growth-stage companies across technology, education, digital health, climate, food, wellness, energy, agriculture, safety and care, and the environment in the United States. It emphasizes impact investing, partnering with experienced teams to build category-defining solutions in education, safety and care, and the environment, aiming to scale revenue in ways that improve lives. Notable portfolio companies include 2U, ShotSpotter, Trilogy Education, and Ready Responders.

Established in 2005, SMBC Venture Capital is a Tokyo-based corporate venture capital arm of Sumitomo Mitsui Banking Corporation. It invests primarily in early-stage companies operating within the information technology, life sciences, services, and manufacturing sectors.