IndieBio

Fermeate is a stealth-mode biotechnology company that specializes in photomolecular fermentation technology. This innovative approach aims to enhance sustainability and efficiency within the biomanufacturing industry.

Capro-X Inc., founded in 2017 and based in Ithaca, New York, is an ag-tech company focused on improving sustainability within the dairy industry. The company specializes in developing a fermentation bioprocess technology that converts acid whey, a byproduct of Greek yogurt production, into bio-oils. Capro-X offers WheyAway, a treatment technology utilizing naturally occurring, non-GMO microbes to transform dairy waste streams into clean water and natural bio-oils. This process occurs at the site of waste generation, addressing the environmental challenges posed by acid whey while producing valuable bio-oil from what would otherwise be discarded material. The company serves the dairy industry by providing a solution that enhances sustainability and increases yield over time.

Materia Bioworks is a pioneering company that develops data-driven informatics tools to facilitate the creation and adoption of sustainable biomaterials. Their AI-powered platform streamlines the process of developing and manufacturing biomaterial products, from sourcing materials to final production. This enables material scientists, product developers, suppliers, and converters to accelerate and enhance their work in biomaterial applications, fostering a more sustainable future across various industries.

Prellis Biologics is a biotechnology company based in San Francisco, founded in 2016, focused on bioprinting vascularized human tissues and organs for drug development, disease modeling, and transplantation. Its platform enables rapid, high-resolution printing of tissues and organoids, including lymph node models, to reproduce human immune responses. This capability supports antibody discovery, immunogenicity assessment, and tumor–immune studies, aiming to accelerate early-stage drug discovery and translational pharmacology while advancing the development of tissue and organ therapies.

Puna Bio specializes in developing biological products for the agricultural sector. Based in Buenos Aires, Argentina, the company focuses on enhancing crop nutrition using extremophile microorganisms, aiming to improve yields and soil quality sustainably.

Particella is a biotechnology company that specializes in developing a proprietary oral lipid nanoparticle technology designed to deliver mRNA and other nucleic acids. This innovative approach aims to transform the administration of biological medicines by utilizing the intestinal tract to facilitate the secretion of proteins into the bloodstream. By enabling the oral delivery of protein biologics, Particella's technology seeks to address the limitations of current methods, ultimately allowing healthcare providers to prevent gastrointestinal diseases in patients more effectively. The company's advancements hold the potential to create a new category of medicines, enhancing the accessibility and efficacy of treatments.

Farm Minerals is a pioneering agricultural company that produces innovative, emissions-free NPK fertilizers at market prices, without compromising on quality or cost. Utilizing proprietary carbon capsule technology, the company enhances nutrient bioavailability, boosting efficiency up to 100 times compared to traditional inputs. By avoiding the Haber-Bosch process, Farm Minerals eliminates CO₂ emissions, reduces nutrient runoff, and minimizes waste. Its product line combines essential macro and microelements, promoting crop performance and animal health, and contributing to sustainable, high-yield agriculture.

Giraffe Bio specializes in developing biomolecular technology to enhance the efficiency and sustainability of critical mineral extraction. Their platform tailors biomolecules to the specific geology of each mine, boosting metal recovery, reducing water usage, and minimizing environmental impact. This is achieved by integrating biology, artificial intelligence, and hardware to optimize extraction processes, enabling clients to improve recovery rates and reduce extraction times.

Ten63 Therapeutics, Inc. is a biotechnology company based in Chapel Hill, North Carolina, focused on developing potent therapeutics for medically validated yet undruggable targets. Founded in 2017, the company utilizes its innovative platform, COPPER, which combines machine learning-based computational chemistry with advanced physical modeling to explore an extensive chemical space. This approach allows Ten63 Therapeutics to discover novel drug candidates for some of the most lethal diseases by employing proprietary algorithms for scaffold redesign and optimizing chemical design. By integrating these technologies, the company aims to produce durable therapies and improve drug resistance prediction, ultimately addressing challenges in drug development for previously intractable targets.

Founded in 2023, AlkaLi Labs is a biotechnology company based in San Francisco. It specializes in recovering critical minerals like lithium and cobalt from industrial waste streams using bioengineering solutions.

Unlocked Labs develops targeted probiotics designed to manage specific health conditions. Their first product focuses on reducing kidney stone risk by digesting a stone-forming compound found in healthy foods like leafy vegetables.

BioLattice is a biotechnology company focused on developing tissue-engineered cornea technology. Their primary goal is to provide a viable alternative to donor tissue for full-thickness corneal transplants. The company's innovative technology offers a corneal prototype with vision-correcting capabilities, aiming to restore sight for patients requiring corneal transplants.

Vitarka Therapeutics is a London-based company that specializes in developing medical technologies and solutions aimed at treating various types of cancer. The company has created a targeted non-viral delivery platform designed for intracellular targets, particularly in oncology, neuroscience, and neurodegeneration. This innovative platform works by activating the immune system and normalizing tumor vasculature, significantly improving outcomes for late-stage cancer patients, including those with lung, colon, and breast cancers. By utilizing re-engineered pore-forming proteins, Vitarka Therapeutics enables cell-specific targeting and endosomal release of therapeutic cargo, providing cancer patients with improved prospects for leading normal lives and maintaining hope for the future.

VIAN Therapeutics is an early-stage biotechnology company focused on transforming retinal disease treatment. Its lead product, a first-in-class non-invasive eyedrop, aims to replace invasive injections for conditions like age-related macular degeneration and diabetic macular edema.

Asterix Foods is a biotechnology company based in Tel Aviv, Israel, founded in 2022. The company specializes in developing protein production through plant-cell culture techniques, focusing on the creation of bioactive proteins for food applications. Asterix Foods aims to provide scalable, functional, and complex proteins that are derived from plant cell cultures, offering an animal-free alternative for consumers.

Sci-Lume Labs specializes in the development of innovative, bio-based and biodegradable fibers designed to replace conventional petrochemical fibers like nylon and polyester. Their high-performance materials maintain the functionality and versatility of traditional synthetics while addressing environmental concerns, catering to textile and apparel manufacturers seeking sustainable alternatives.

Ceal is a Climate Tech Manufacturing firm making energy efficient technology for carbon dioxide removal.

Quorum Earth, based in Brooklyn, New York, is a pioneering agricultural technology company. It specializes in the development of innovative, eco-friendly pesticides, harnessing the power of the fungal kingdom to create products that are safe for the planet and effective in controlling pests. Currently, the company operates in stealth mode.

Sun Genomics, Inc. is a microbiome health company based in San Diego, California, specializing in customized probiotics aimed at addressing dysbiosis. Founded in 2014, the company’s flagship product, Floré, combines a gut microbiome test with personalized probiotic formulations tailored to individual gut profiles, assessed through whole-genome sequencing. The Floré Gut Test includes a microflora collection kit, a comprehensive microflora profile analysis, and wellness consultations. Additionally, Sun Genomics offers Floré Tots, a probiotic solution designed for children up to age 12, which comes in a convenient powder form that can be easily mixed with beverages. The company sells its products online, providing an automatic renewal service to enhance customer convenience.

Capra Biosciences is a biotechnology company that develops bioreactor technology to enable efficient, low-carbon production of bio-based chemicals. Its biofilm bioreactor platform reduces downstream processing requirements and costs in bio-manufacturing and supports the production of hydrophobic products, including fuels, retinol, and performance lubricants.

Synplexity is a biotechnology company located in New Castle, Delaware, specializing in mutational scanning and multiplexed gene synthesis through advanced artificial intelligence technology. The company operates a large-scale gene synthesis and proteomics discovery platform that utilizes microdroplets as microreactors. This innovative approach allows for the efficient creation of multiplex gene libraries, which have applications across various sectors, including therapeutics, biomanufacturing, agriculture, and climate systems. Synplexity aims to drive advancements in healthcare and other industries through its cutting-edge genetic technologies.

Founded in 2022 and headquartered in Berkeley, California, Laguna Bio develops a drug discovery platform designed to selectively activate and expand the innate immune system against cancer. The company focuses on providing a specific type of T cell for the immune system to fight solid tumors by increasing the response rate of bispecific antibody drugs.

FREZENT is a biotechnology company focused on developing innovative therapeutics for advanced-stage cancer patients. It specializes in creating biological inhibitors that target cancer-specific lipid metabolism, aiming to prevent the reactivation of dormant cancer cells.

NanoPlume is a biomaterial manufacturer specializing in the large-scale production of innovative, eco-friendly biomaterials, notably Bio-Aerogel. The company focuses on creating advanced insulating biomaterials and aerogels, aiming to enhance energy and space efficiency, as well as promote circularity across various industries. By utilizing organic and recycled feedstocks and green technology, NanoPlume reduces waste and minimizes energy consumption. Its products are designed to insulate cargo boxes in the cold chain healthcare logistics sector, reducing payload and energy consumption, and extending battery range.

Bactery is a manufacturer of innovative bacteria-powered batteries, known as bacteries, which harness microbial processes in soil to self-recharge. This technology offers a continuous source of clean electricity, functioning effectively regardless of weather conditions or geographic location. Bactery's environmentally friendly batteries are particularly suited for powering remote applications, such as field sensors and Internet of Things (IoT) devices, making them an ideal solution for sustainable energy needs in agriculture and other sectors.

Huue is a company specializing in sustainable dyeing solutions for the fashion and textile industries, particularly focusing on the denim supply chain. It employs innovative biotechnology to produce bio-synthesized dyes through a fermentation process involving naturally occurring microorganisms. This method not only eliminates the need for toxic chemicals traditionally used in dye production but also utilizes renewable resources, making it an eco-friendly alternative. By offering greener options for color production, Huue aims to support the industry's transition towards more sustainable practices, ultimately contributing to a more environmentally responsible approach to fashion.

DisperseBio is a Biotechnology Research firm developing a mechanism to counter microbial contamination on natural surfaces like human body.

Metabolic Psychiatry Labs is a mental healthcare company that provides remote treatment solutions for mental illnesses. Their platform integrates metabolic and mental health research, data tracking, metabolic interventions, and personalized medical care, enabling patients to receive effective treatments from home. The company offers assessments, lab tests, and wellness solutions based on metabolic therapy.

Mothership Materials specializes in converting agricultural waste into valuable biomolecules using its proprietary Targeted Molecular Recovery (TMR) technology. The company's process efficiently extracts proteins, lipids, antioxidants, sugars, and cellulose from waste streams, enabling agricultural producers and waste managers to create a circular economy and maximize waste value.

Minutia is a biotechnology company focused on developing innovative stem cell-derived transplants aimed at treating Type 1 Diabetes. The company specializes in creating insulin-producing cell transplants that incorporate proprietary nanosensors, allowing for real-time monitoring of transplant status. These immune-evasive cells are designed for subcutaneous implantation, addressing common challenges associated with transplant procedures. By advancing this technology, Minutia seeks to transform the clinical landscape for diabetes management and cell replacement therapies, ultimately working towards a functional cure for this condition.

Gatehouse Bio is a biotech company based in Waltham, Massachusetts, founded in 2016. The company specializes in the development of therapies utilizing a novel bioinformatics platform that focuses on small ribonucleic acid (RNA) biomarkers. This platform is designed to classify patient samples with binary accuracy and identifies disease-associated mutations, enabling the creation of targeted therapeutics. By employing artificial intelligence, Gatehouse Bio aims to analyze small RNA genes and design oligonucleotides that can effectively counteract the effects of these mutations. Their research and development efforts target therapeutic areas with known heterogeneity, such as fibrosis, inflammation, and neurodegeneration, with the goal of unlocking the potential for improved patient outcomes through personalized medicine.

Founded in 2021, Sóliome is a biotechnology company based in San Francisco, California. It specializes in developing protein-based sunscreens that are safe and effective, using molecules naturally produced by the human body to protect against harmful UV rays.

BioMetallum is a biomining company specializing in sustainable metal extraction. It designs and develops solutions, primarily focused on lithium, using microorganisms to enhance efficiency and minimize environmental impact. The company's services promote a circular economy, aiming to enable a healthier, more sustainable society.

Calyx develops advanced sensor platforms that monitor various parameters in poultry farming with exceptional specificity and sensitivity. The company combines AI computer vision technology, bio-engineered sensors, and data science to address complex challenges in the poultry industry.

Asta Bio is a biotechnology company specializing in the development of radiotherapeutics for cancer treatment. It focuses on combining the alpha-emitting radioisotope 211-Astatine with multivalent single-domain antibodies to deliver targeted alpha radiation to tumor cells, sparing healthy cells. This approach aims to effectively destroy cancer cells by breaking their DNA strands.

DNAzyme is a biotechnology company specializing in the development of enzymes derived from Antarctic extremophile microorganisms as active ingredients for skin health applications. Utilizing recombinant DNA repair technology, the company produces highly pure enzymes at an industrial scale, enabling clinicians to create innovative solutions for skin health and rejuvenation in both the cosmetic and pharmaceutical industries.

PhytoGenesis is a company that specializes in developing sustainable plant protection products. It focuses on creating safe and non-toxic alternatives to traditional fungicides and pesticides, using plant-based compounds. The company's technology ensures effectiveness across a broad spectrum of crops, including grains, feed, fiber, oil, vegetables, and fruits. PhytoGenesis aims to minimize environmental impact while maintaining crop health and productivity, contributing to global food security.

Tinkeso Therapeutics is a biotechnology company specializing in the development of innovative, off-the-shelf cell therapies for treating cancer and autoimmune diseases. The company focuses on creating allogeneic chimeric antigen receptor (CAR) engineered natural killer T (NKT) cell therapies, which use NKT cells to target and destroy cancer cells or modulate the immune response in autoimmune conditions. This approach aims to increase treatment accessibility and scalability by utilizing non-patient-specific cells.

microTERRA harnesses Lemna, an aquatic plant with water-cleaning capabilities, to produce sustainable functional ingredients for the food industry. Its flagship product, Flora, enhances sweetness perception while reducing sugar and masking unwanted notes from high-intensity sweeteners.

BugBiome is a biotechnology company that develops eco-friendly bio-repellents to create natural pest control products. It focuses on identifying and enhancing beneficial microbes that deter pests organically, providing an alternative to traditional chemical methods. The company aims to minimize environmental impact and promote sustainable pest management practices, potentially benefiting sectors such as agriculture and households.

heXem bio specializes in recording solutions for the early development of humans for longevity.

Restoring crops' ability to defend against pests.

Fermeate is a stealth-mode biotechnology company that specializes in photomolecular fermentation technology. This innovative approach aims to enhance sustainability and efficiency within the biomanufacturing industry.

Capro-X Inc., founded in 2017 and based in Ithaca, New York, is an ag-tech company focused on improving sustainability within the dairy industry. The company specializes in developing a fermentation bioprocess technology that converts acid whey, a byproduct of Greek yogurt production, into bio-oils. Capro-X offers WheyAway, a treatment technology utilizing naturally occurring, non-GMO microbes to transform dairy waste streams into clean water and natural bio-oils. This process occurs at the site of waste generation, addressing the environmental challenges posed by acid whey while producing valuable bio-oil from what would otherwise be discarded material. The company serves the dairy industry by providing a solution that enhances sustainability and increases yield over time.

Oobli develops healthy, low-calorie protein sweeteners derived from exotic plants. These rare compounds offer great taste without affecting blood sugar levels or gut microbiome. The company has secured regulatory approvals such as FDA 'no questions' letters and GRAS status for multiple proteins.

CellCrine focuses on discovering enzymes that transform cell culture for the cell-based meats industry. CellCrine was founded in 2021and was headquartered in United, States.

Transition Biomining is a technology-focused company specializing in copper ore mining. It employs data-driven methods to enhance copper extraction and mining efficiency. The company's core innovation lies in optimizing microbial communities for heap-leaching operations, aiming to boost metal recovery rates, expedite extraction, and minimize environmental impact. By harnessing the power of microbiomes, Transition Biomining provides sustainable and data-driven solutions to improve clients' extraction processes in both new and existing heap-leaching operations.

MycoWorks is a biotechnology company specializing in the production of non-plastic and non-animal materials. Utilizing fungal mycelium, they create energy-efficient and biodegradable alternatives to plastic foams, textiles, woods, and leather for various industries such as aerospace, automotive, apparel, and architecture.

NovoNutrients is a pioneering biotechnology company specializing in the conversion of waste CO2 emissions into high-value proteins and additives for use in food and animal feed. The company's proprietary technology employs advanced gas fermentation systems and custom microbes to transform industrial waste CO2, hydrogen, and oxygen into safe, natural single-cell protein ingredients. This innovative process not only addresses global food security by providing a sustainable alternative protein source but also contributes to climate change mitigation through carbon capture and utilization.

OncoPrecision develops a patient micro avatar platform that uses single-cell high-throughput biology and machine learning to provide comprehensive patient-derived phenotypic biomarkers. This enables oncologists to tailor cancer therapy across modalities, improving patient success through data-driven decisions based on patient-derived samples.

BugBiome is a biotechnology company that develops eco-friendly bio-repellents to create natural pest control products. It focuses on identifying and enhancing beneficial microbes that deter pests organically, providing an alternative to traditional chemical methods. The company aims to minimize environmental impact and promote sustainable pest management practices, potentially benefiting sectors such as agriculture and households.

Avalo is a plant biology company that employs interpretable machine learning, genomic discovery, and evolutionary theory to expedite the development of new crops tailored for future agricultural needs. Utilizing AI-assisted plant breeding methods, Avalo creates non-GMO products that foster natural biodiversity. Its core technology, a discovery engine, can swiftly identify genetic bases of complex traits even in understudied crops, reducing time and cost significantly compared to traditional methods. This enables Avalo to forecast and enhance crop traits like drought tolerance and nutrient density, adapting agriculture to changing climates.

Farm Minerals is a pioneering agricultural company that produces innovative, emissions-free NPK fertilizers at market prices, without compromising on quality or cost. Utilizing proprietary carbon capsule technology, the company enhances nutrient bioavailability, boosting efficiency up to 100 times compared to traditional inputs. By avoiding the Haber-Bosch process, Farm Minerals eliminates CO₂ emissions, reduces nutrient runoff, and minimizes waste. Its product line combines essential macro and microelements, promoting crop performance and animal health, and contributing to sustainable, high-yield agriculture.

Helex is a biotechnology company developing genomic medicines for kidney-related diseases. It leverages its own genomics data, bioinformatics, and an intelligent data-driven platform to design, verify, and deliver therapy-specific gRNAs, with a focus on non-viral targeted delivery and genome editing for renal indications. The company's platform uses data-driven deep-learning models and high-throughput sequencing data from CRISPR edits in human cell lines to generate reliable predictions and validate them in-house. By combining these capabilities, Helex aims to accelerate CRISPR-based drug research and the development of cell and gene therapies for kidney conditions, offering precise and scalable renal therapeutics.

Calder Biosciences engineers next-generation vaccines using its proprietary 3D-Vaxlock technology. This platform generates molecular staples that lock vaccines into their most potent shape, enhancing immune response and stability. Calder's initial focus is on developing a universal flu vaccine and an RSV vaccine for the elderly. Their vaccines aim to protect against life-threatening diseases with improved safety, efficacy, and durability, reducing healthcare burden globally.

ClimateCrop develops gene editing and related plant technologies to enable crops to store more carbon and energy, with the goal of increasing yields in biomass and fruit. The approach also enhances crop resilience to extreme weather, supporting climate adaptation and more reliable production for agricultural companies. Founded in 2021 and based in Ness Ziona, the company focuses on leveraging plant energy capture to boost productivity.

Finless Foods Inc. is a biotechnology company based in Emeryville, California, that specializes in producing seafood products for human consumption using cellular-agriculture technologies. Founded in 2017, the company focuses on cultivating marine-animal cells to create sustainable fish and seafood alternatives, including bluefin tuna. Finless Foods aims to provide a variety of food options that cater to diverse tastes and dietary preferences while promoting responsible production practices. By offering accessible plant-based and cell-cultured seafood alternatives, the company seeks to contribute to better ocean health and foster a more sustainable future for food consumption.

Bloomlabs provides a method to catalyze waste value by regenerating it as adaptable and appealing bio-plastics and textile fibers. It envisions a future in which outmoded, resource-intensive processes are phased out in favor of cutting-edge, sustainable, and scalable alternatives.

Cayuga Biotech is a biotechnology company developing innovative hemostatic drugs and devices aimed at reducing uncontrollable bleeding, a leading cause of death from traumatic injuries. Its polyphosphate-based drug accelerates the body's natural clotting process to contain bleeding at the injury site, minimizing potential side effects. Cayuga focuses on treating traumatic hemorrhage and rare bleeding disorders.

California Cultured is a food company based in Davis, California, that specializes in creating sustainable, lab-grown cocoa and coffee through advanced cellular agriculture techniques. Founded in 2020, the company focuses on producing cocoa that is less bitter and requires less sugar, while also ensuring its products are healthier for consumers. By stimulating cocoa cell growth using common food ingredients, California Cultured aims to provide high-quality cocoa products that are free from the ethical issues traditionally associated with cocoa production, such as slavery and deforestation. This innovative approach allows customers to enjoy delicious and sustainable cocoa without the environmental and social drawbacks of conventional methods.

Nukoko is a bean-to-bar manufacturer specializing in cocoa-free chocolate. Utilizing UK-sourced ingredients and patent-pending technology, the company produces healthier, environmentally friendly chocolate.

AquaLith Advanced Materials specializes in the development of innovative lithium-ion battery materials. The company has secured exclusive rights to a portfolio of patents from the University of Maryland, which focus on advancements made by researchers in the field of chemical and materials engineering. AquaLith's technology includes an ultra-high energy cathode, a novel silicon anode, and a non-flammable aqueous electrolyte, all designed to enhance the performance of lithium-ion batteries. This technology addresses key challenges such as efficiency in low temperatures, faster charging times, and improved safety by reducing fire risks associated with short circuits. The company's materials aim to provide high energy density while being cost-effective and abundant, ultimately benefiting consumer electronics and other applications in need of reliable battery solutions.

Avisa Myko is a biotechnology company based in San Francisco, California. It specializes in the production of melanin, a natural pigment with applications in cosmetics, biomedicine, organic semiconductors, biosensors, and latex products. The company's patented technology enables large-scale production of soluble, affordable melanin, offering protection against ionizing radiation and contributing to better health and environmental sustainability.

Terra Bioindustries produces plant-based protein derived from underutilized waste materials like spent grains from beer manufacturing. This process transforms these unused parts into functional vegan protein, offering clients sustainable alternatives to soy and pea protein for use in meat and dairy replacements.

Reactosome is a biotechnology company that develops synthetic nuclei for gene therapy. Its core product, a synthetic nucleus, operates continuously within cells, mimicking the natural nucleus to affect multiple genes simultaneously. This approach aims to enhance the safety and longevity of gene expression, thereby enabling the development of treatments for complex diseases such as cancer and age-related disorders.

Bioeutectics develops and supplies high-performance, natural solvents for industrial processes. Utilizing eutectic technology and renewable resources, the company produces eco-friendly alternatives to petrochemical solvents, serving industries such as personal care, food ingredients, agro-tech, and green tech.

Founded in 2013, ZymoChem develops eco-friendly chemical production processes using engineered microbes. These processes convert renewable feedstocks like sugars into industrial chemicals, minimizing carbon loss and enabling cost-competitive bio-based manufacturing.

Chronus Health develops a portable diagnostic device for delivering point-of-care lab results in minutes. Its device enables real-time diagnosis at the point-of-care, improving time to care and patient outcomes.

Voyage Foods develops sustainable alternatives to popular foods. Using natural ingredients and proprietary technology, they create products like nut-free spreads, cocoa-free chocolate, and bean-free coffee that maintain original taste and nutrition without environmental compromise.

Sun Genomics, Inc. is a microbiome health company based in San Diego, California, specializing in customized probiotics aimed at addressing dysbiosis. Founded in 2014, the company’s flagship product, Floré, combines a gut microbiome test with personalized probiotic formulations tailored to individual gut profiles, assessed through whole-genome sequencing. The Floré Gut Test includes a microflora collection kit, a comprehensive microflora profile analysis, and wellness consultations. Additionally, Sun Genomics offers Floré Tots, a probiotic solution designed for children up to age 12, which comes in a convenient powder form that can be easily mixed with beverages. The company sells its products online, providing an automatic renewal service to enhance customer convenience.

Unlocked Labs develops targeted probiotics designed to manage specific health conditions. Their first product focuses on reducing kidney stone risk by digesting a stone-forming compound found in healthy foods like leafy vegetables.

RyboDyn is a biotechnology research company focused on developing innovative therapeutics aimed at training the immune system to identify and eliminate cancer from within the body. By leveraging cutting-edge scientific breakthroughs, RyboDyn creates advanced treatments that promise significant improvements in the management of terminal diseases and various ailments. The company's commitment to enhancing medicine through its research positions it at the forefront of the fight against cancer, with the potential to transform patient care and outcomes.

Prellis Biologics is a biotechnology company based in San Francisco, founded in 2016, focused on bioprinting vascularized human tissues and organs for drug development, disease modeling, and transplantation. Its platform enables rapid, high-resolution printing of tissues and organoids, including lymph node models, to reproduce human immune responses. This capability supports antibody discovery, immunogenicity assessment, and tumor–immune studies, aiming to accelerate early-stage drug discovery and translational pharmacology while advancing the development of tissue and organ therapies.

Hypercell Technologies specializes in developing innovative tools for controlling infectious diseases in animals. The company's core focus is on creating rapid, accurate diagnostic tools using molecular biology techniques, which enable veterinarians to detect and manage infections swiftly. Additionally, Hypercell develops monoclonal antibodies designed to proactively control viruses in production animal reservoirs, aiming to prevent potential zoonotic disease outbreaks in humans by addressing the source in animals.

Lillianah Technologies is a company dedicated to developing innovative carbon capture technology aimed at restoring marine ecosystems affected by pollution and other environmental challenges. Comprising a team of scientists, Lillianah focuses on optimizing the biological pump in oceans, which is crucial for maintaining ecological balance. By harnessing the ocean's potential, the company seeks to address the detrimental impacts of human activity, such as fertilizer runoff, and contribute to reversing environmental degradation. Through its efforts, Lillianah Technologies aspires to create sustainable solutions that benefit both the oceans and the broader environment.

BioFluff is a manufacturer specializing in plant-based fur designed to serve the fashion industry by providing a sustainable alternative to animal and plastic fur. The company utilizes a patented process along with retrofitted equipment to ensure a scalable production of its eco-friendly materials. Sourced from organic renewable fiber plants, BioFluff’s products are developed without gene splicing, gene editing, or the use of petrochemicals and unsustainable raw-oil derivatives. This commitment to sustainability extends to its customization services, allowing clients to personalize their materials according to specific features such as fur length, fiber density, color, top fur strength, bottom fur insulation properties, and suppleness. By combining innovation with customization options, BioFluff aims to meet the growing demand for luxury, sustainable textiles within the fashion industry.

Founded in 2021, Pyrone Systems specializes in developing biopesticides that combine biological and chemical approaches. The company aims to create safe, effective, and sustainable products by utilizing scalable biology-based methodologies.

Founded in 2018, Rizlab Health specializes in developing compact blood diagnostic devices. Their flagship product is CytoTracker, a pocket-sized, wireless analyzer powered by artificial intelligence, designed to deliver rapid and affordable white blood cell count analysis.

FREZENT is a biotechnology company focused on developing innovative therapeutics for advanced-stage cancer patients. It specializes in creating biological inhibitors that target cancer-specific lipid metabolism, aiming to prevent the reactivation of dormant cancer cells.

BioAesthetics develops tissue-engineered nipple-areolar complex grafts to support breast reconstruction after mastectomy. The graft is designed as a scaffold for the patient's own cells to populate and regenerate the nipple and areola during reconstruction, aiming to improve cosmetic and reconstructive outcomes. The company originated as a Tulane University spin-out and was founded in 2015.

Gatehouse Bio is a biotech company based in Waltham, Massachusetts, founded in 2016. The company specializes in the development of therapies utilizing a novel bioinformatics platform that focuses on small ribonucleic acid (RNA) biomarkers. This platform is designed to classify patient samples with binary accuracy and identifies disease-associated mutations, enabling the creation of targeted therapeutics. By employing artificial intelligence, Gatehouse Bio aims to analyze small RNA genes and design oligonucleotides that can effectively counteract the effects of these mutations. Their research and development efforts target therapeutic areas with known heterogeneity, such as fibrosis, inflammation, and neurodegeneration, with the goal of unlocking the potential for improved patient outcomes through personalized medicine.

Diptera.ai is a Jerusalem-based company specializing in innovative mosquito control solutions. The firm has developed a technology that employs the sterile insect technique, utilizing advanced optics, computer vision, and artificial intelligence. Its ready-to-use module is designed to release sterile male mosquitoes over several weeks, allowing municipal corporations to implement large-scale mosquito control initiatives effectively. This approach eliminates the need for traditional mosquito rearing and sorting facilities, making the technology more affordable and accessible for municipalities. By focusing on biological solutions, Diptera.ai aims to address the challenges posed by mosquito-borne diseases and improve public health outcomes.

Calder Biosciences engineers next-generation vaccines using its proprietary 3D-Vaxlock technology. This platform generates molecular staples that lock vaccines into their most potent shape, enhancing immune response and stability. Calder's initial focus is on developing a universal flu vaccine and an RSV vaccine for the elderly. Their vaccines aim to protect against life-threatening diseases with improved safety, efficacy, and durability, reducing healthcare burden globally.

BryoSphere is a company specializing in the manufacturing of specialty chemicals, employing moss plants and biotechnology methods in the production of their goods. The company is currently focused on the development of two key products: one for addressing skin hyperpigmentation in topical treatments, and another as an anti-cancer drug.

Xias Bio is a biotechnology company focused on producing recombinant proteins. It specializes in creating advanced soluble ingredients with improved attributes such as enhanced gel and film formation, and antioxidant properties. The company's core expertise lies in developing non-immunogenic natural motifs to deliver functionalities for research, beauty, and healthcare applications.

Terra Bioindustries produces plant-based protein derived from underutilized waste materials like spent grains from beer manufacturing. This process transforms these unused parts into functional vegan protein, offering clients sustainable alternatives to soy and pea protein for use in meat and dairy replacements.

Veloz Bio is a biotechnology company founded in 2021 and based in Monterrey, Nuevo León. The company specializes in molecular farming to develop and manufacture animal-free and alternative proteins. Utilizing a rapid protein production system, Veloz Bio leverages efficient plant metabolism to create sustainable and affordable protein solutions. This innovative approach enables the company to support biotechnology firms by providing expertise in key areas such as protein production, supercritical fluid extraction, and membrane purification. Through its focus on scalable protein development, Veloz Bio aims to contribute to the advancement of alternative protein sources in the food industry.

Founded in 2014, QuantumCyte develops an automated tissue dissection system that uses digital maps to isolate regions of interest containing informative biomarkers. This platform aims to improve cancer outcomes by enabling precise cellular data analysis for predicting drug efficacy.

CroBio is an agricultural biotechnology company developing a sustainable solution for managing global agricultural drought. It uses genetically engineered root-associated bacteria to produce biomaterials that retain water in the soil, enhancing crop resilience and reducing irrigation requirements.

Cell BioEngines is a clinical-stage biotechnology company specializing in developing 'off-the-shelf' stem cell therapies as drugs for treating human diseases. The company's core platform enables the production of high-quality, pure, and potent cell products at scale using a universal blood stem cell-derived technology.

Nukoko is a bean-to-bar manufacturer specializing in cocoa-free chocolate. Utilizing UK-sourced ingredients and patent-pending technology, the company produces healthier, environmentally friendly chocolate.

Avisa Myko is a biotechnology company based in San Francisco, California. It specializes in the production of melanin, a natural pigment with applications in cosmetics, biomedicine, organic semiconductors, biosensors, and latex products. The company's patented technology enables large-scale production of soluble, affordable melanin, offering protection against ionizing radiation and contributing to better health and environmental sustainability.

Re-Fresh Global is a company focused on advancing the circular economy in the textile industry by providing innovative solutions for managing textile waste. Utilizing a patented method, the company addresses the growing issue of textile waste through advanced waste management technologies. Re-Fresh Global initiates and implements various projects aimed at promoting circularity, offering training and fostering international collaborations. Their services include smart collection and separation techniques, as well as low-cost upcycling processes for large volumes of low-value textile waste. The company engages with its customers through phone, email, and online applications to address inquiries and support their needs.

Cereswaves is a specialized machinery manufacturer focused on mining, agriculture, and construction processes.

Transition Biomining is a technology-focused company specializing in copper ore mining. It employs data-driven methods to enhance copper extraction and mining efficiency. The company's core innovation lies in optimizing microbial communities for heap-leaching operations, aiming to boost metal recovery rates, expedite extraction, and minimize environmental impact. By harnessing the power of microbiomes, Transition Biomining provides sustainable and data-driven solutions to improve clients' extraction processes in both new and existing heap-leaching operations.

Bloomlabs provides a method to catalyze waste value by regenerating it as adaptable and appealing bio-plastics and textile fibers. It envisions a future in which outmoded, resource-intensive processes are phased out in favor of cutting-edge, sustainable, and scalable alternatives.

TippingPoint Biosciences is developing therapeutics that target abnormal DNA packaging states in diseases such as cancer.

Founded in 2022, Carbonade is an innovative chemical manufacturing company based in Ness Ziona, Israel. It specializes in patented Electro-Chemical CO2 reduction solutions, aiming to disrupt the industry and mitigate climate change by converting chemical compounds into sustainable carbon-based products.

California Cultured is a food company based in Davis, California, that specializes in creating sustainable, lab-grown cocoa and coffee through advanced cellular agriculture techniques. Founded in 2020, the company focuses on producing cocoa that is less bitter and requires less sugar, while also ensuring its products are healthier for consumers. By stimulating cocoa cell growth using common food ingredients, California Cultured aims to provide high-quality cocoa products that are free from the ethical issues traditionally associated with cocoa production, such as slavery and deforestation. This innovative approach allows customers to enjoy delicious and sustainable cocoa without the environmental and social drawbacks of conventional methods.