Elm Street Ventures

Elm Street Ventures is a venture capital firm specializing in investments in seed, startups, and early stage. It seeks to invest in life sciences and technology companies founded on intellectual property developed at Yale University and other research institutions in the region (from New York City through Southern New England). In life sciences the firm focuses on therapeutics, medical devices, laboratory tools, diagnostics, research tools and services, materials, healthcare, and healthcare services and in technology companies it invests in software, green technology, clean technology, green chemistry, information technology, mobile, and social web. The firm prefers to invest in or near New Haven, however this is not a requirement. It typically makes initial investments from several hundred thousand dollars to $1 million or more, with follow-on investments. The firm may invest in a syndicate with other institutional investors. Elm Street Ventures is based in New Haven, Connecticut.

Rob Bettigole

Managing Partner

Brian Dixon

Venture Partner

CM

Chris McLeod

Managing Partner

RS

Rick Stahl

Venture Partner

DT

Dean Takahashi

Founder and Executive Director, Yale Carbon Containment Lab

23 past transactions

Cybrexa, Inc.

Series B in 2021
Cybrexa, Inc. develops DNA repair inhibitors for radio- and chemo-sensitizers in cancer therapeutics. The product consists of peptide-based technology that directly targets tumor microenvironment. Cybrexa, Inc. was formerly known as Cybrexa, Inc. The company was founded in 2016 and is based in New Haven, Connecticut.

Halda Therapeutics

Series A in 2019
Halda Therapeutics is a research-stage drug discovery company, seeking to create the next generation of precision medicine based on a novel therapeutic modality which may be a platform for a number of disease states.
Kolltan Pharmaceuticals, Inc., is a private company founded in 2007 that is developing novel monoclonal antibody (mAb) drugs targeting receptor tyrosine kinases (RTKs). Kolltan's primary targets derive from seminal discoveries made in the laboratory of Dr. Joseph Schlessinger, Chairman of the Department of Pharmacology at the Yale School of Medicine, and in Kolltan’s laboratories. Dr. Schlessinger's laboratory has characterized a novel molecular mechanism underlying activation of RTKs providing, for the first time, a clear molecular explanation — at atomic resolution — for the oncogenic activity of mutations that have been identified in a variety of human cancers.

SeeClickFix, Inc.

Venture Round in 2015
SeeClickFix provides tools for residents and governments to communicate for all sizes, populations, and budgets. The company empowers citizens, community organizations, and governments to care for and improve their neighborhoods by providing technology tools that promote civic engagement and government transparency. They focused reports allow officials at all levels to evaluate public service performance, plan for improvements, and have the facts necessary to make data-driven decisions. SeeClickFix was established in 2008 and is based in New Haven, Connecticut, United States.

Iconic Therapeutics

Venture Round in 2018
Iconic Therapeutics, Inc. operates as a biopharmaceutical company that translates tissue factor biology in angiogenesis, inflammation, and metastasis to develop new therapeutics for retinal disease and cancer. Its products include ICON-1, a fusion protein designed to address the basis of vision loss in age-related macular degeneration. Iconic Therapeutics, Inc. was incorporated in 2002 and is based in South San Francisco, California.

Arvinas

Series A in 2013
Arvinas is a pharmaceutical company that focuses on developing novel therapeutics to treat a variety of diseases including cancer, pro-inflammatory, autoimmune and rare diseases. Its proprietary approach is the targeting of disease-causing proteins for degradation thus eliminating them from the body. The company was founded in 2013 and is headquartered in Connecticut, United States.

zid

Seed Round in 2019
Zid is an e-commerce in a box - solution that any retailer can use to start their eRetail. Zid helps them to build their own eStores (with their own name and identity) and integrates them with the supply chain players to enable them to manage and with ease. The company aims to enable the retail sector to enter the world of electronic retail in an easy and professional. Zid was founded in 2017 and based in Riyadh, Ar Riyad, Saudi Arabia.

P2 Science

Series C in 2020
P2 Science, Inc., a bio-renewable chemistry company, develops and produces specialty chemicals using renewable feedstocks. It offers flavor, fragrance, cosmetics, and petrochemical fragrance ingredients. The company serves flavors and fragrances, household cleaning, industrial and institutional cleaning, personal care and cosmetics, polymers, oilfield, agricultural chemicals, mining, environmental cleanup and remediation, paints and coatings, and food markets. P2 Science, Inc. was incorporated in 2009 and is based in Woodbridge, Connecticut.
Accelerated Orthopedic Technologies, Inc. provides instruments to treat articular cartilage defects with custom sizes, shapes, and matching topography. The company was formerly known as Advanced Orthopedic Technologies, Inc. and changed its name to Accelerated Orthopedic Technologies, Inc. in February 2010. Accelerated Orthopedic Technologies, Inc. was incorporated in 2009 and is based in Guilford, Connecticut.

Metagenomix

Seed Round in 2010
Metagenomix is an early-stage biotechnology company developing novel methods of screening microbes for pharmacologically active compounds. Among the indications under investigation are cancer, inflammation and infectious diseases including fungal infections and malaria. The technology also has applications in agriculture.

ShareGrove

Seed Round in 2009
ShareGrove hosts private online conversations that are media-rich, fluid and dynamic. ShareGrove makes it easy to select friends from Facebook (and other networks), and to engage them in real time, or over time, through a single Web interface. Integrated Web search (from Google, Amazon and Yelp), along with inline presentation of media, add richness and expression to ShareGrove conversations, while also generating revenues through affiliate programs.

Retail Optimization

Series B in 2008
Retail Optimization Inc. provides predictive macro optimization analytics to determine the most profitable levels of product selection, category space and inventory investment while enhancing the shopping experience for consumers.

EvolveImmune Therapeutics

Venture Round in 2020
EvolveImmune Therapeutics transforms the discovery and development of novel immunotherapies. By leveraging its proprietary in vivo target discovery platform, EvolveImmune is building a pipeline of novel therapeutic candidates against numerous targets that are expressed on multiple immune cell types. The company’s platform will generate first-in-class treatments for unmet needs in oncology and autoimmune diseases.

P2 Science

Seed Round in 2013
P2 Science, Inc., a bio-renewable chemistry company, develops and produces specialty chemicals using renewable feedstocks. It offers flavor, fragrance, cosmetics, and petrochemical fragrance ingredients. The company serves flavors and fragrances, household cleaning, industrial and institutional cleaning, personal care and cosmetics, polymers, oilfield, agricultural chemicals, mining, environmental cleanup and remediation, paints and coatings, and food markets. P2 Science, Inc. was incorporated in 2009 and is based in Woodbridge, Connecticut.

Desmos, Inc.

Venture Round in 2012
Desmos, Inc. develops a Web-based graphing calculator for students and teachers in the United States and internationally. The company’s solution allows users to graph functions, plot tables of data, evaluate equations, explore transformations, and more. Desmos, Inc. was formerly known as Tutor Trove, LLC and changed its name to Desmos, Inc. in March 2011. The company was founded in 2007 and is based in San Francisco, California.

Artizan Biosciences

Series A in 2019
Artizan Biosciences, Inc. develops small molecule drugs for use in humans. The company use IgA-SEQ technology platform to distinguish disease-driving bacteria from the intestinal microbiota to developing new and potentially curative treatments. Artizan Biosciences, Inc. was founded in 2016 and is headquartered in New Haven, Connecticut.

P2 Science

Series A in 2014
P2 Science, Inc., a bio-renewable chemistry company, develops and produces specialty chemicals using renewable feedstocks. It offers flavor, fragrance, cosmetics, and petrochemical fragrance ingredients. The company serves flavors and fragrances, household cleaning, industrial and institutional cleaning, personal care and cosmetics, polymers, oilfield, agricultural chemicals, mining, environmental cleanup and remediation, paints and coatings, and food markets. P2 Science, Inc. was incorporated in 2009 and is based in Woodbridge, Connecticut.

Saphlux

Series A in 2017
Saphlux, Inc. develops, produces, and commercializes semi-polar gallium nitride (GaN) materials that solve droop and green gap problems in LEDs and lasers. The company offers semi-polar GaN templates in two diameters or customized size (quarters). Saphlux, Inc. was founded in 2014 and is based in New Haven, Connecticut.

BioRelix

Series A in 2007
BioRelix, Inc., a biopharmaceutical company, engages in the discovery and development of anti-biotic drug candidates for the treatment of infectious diseases in the United States. It develops a portfolio of riboswitch-based therapeutic agents to overcome the lethal and devastating causes of bacterial infections. The company was founded in 2005 and is based in New Haven, Connecticut.

Iconic Therapeutics

Venture Round in 2009
Iconic Therapeutics, Inc. operates as a biopharmaceutical company that translates tissue factor biology in angiogenesis, inflammation, and metastasis to develop new therapeutics for retinal disease and cancer. Its products include ICON-1, a fusion protein designed to address the basis of vision loss in age-related macular degeneration. Iconic Therapeutics, Inc. was incorporated in 2002 and is based in South San Francisco, California.

Artizan Biosciences

Series A in 2021
Artizan Biosciences, Inc. develops small molecule drugs for use in humans. The company use IgA-SEQ technology platform to distinguish disease-driving bacteria from the intestinal microbiota to developing new and potentially curative treatments. Artizan Biosciences, Inc. was founded in 2016 and is headquartered in New Haven, Connecticut.

P2 Science

Series B in 2017
P2 Science, Inc., a bio-renewable chemistry company, develops and produces specialty chemicals using renewable feedstocks. It offers flavor, fragrance, cosmetics, and petrochemical fragrance ingredients. The company serves flavors and fragrances, household cleaning, industrial and institutional cleaning, personal care and cosmetics, polymers, oilfield, agricultural chemicals, mining, environmental cleanup and remediation, paints and coatings, and food markets. P2 Science, Inc. was incorporated in 2009 and is based in Woodbridge, Connecticut.

Affomix Corporation

Series A in 2008
Affomix has proprietary technology for rapid, automated, high-throughput selection of human monoclonal antibodies (mAbs). Their mission is to commercialize proprietary mAbs, mAb microarrays and mAb libraries for research, drug discovery, diagnostic and therapeutic applications, with a particular focus on the use of their mAbs for sensitive and accurate measurement of very large numbers of proteins in biological samples.