Curie Capital

Curie Capital is a life science-focused venture capital firm established in 2018 and headquartered in Amsterdam, Netherlands. The firm aims to invest in early-stage companies within the biotechnology, pharmaceutical, and medical technology sectors, with particular emphasis on therapeutics, diagnostics, and medical devices. Founded by Mariette van der Velden and Han de Groot, both of whom possess extensive experience in investing and entrepreneurship, Curie Capital combines their complementary skills and networks to support the development of talented teams and innovative science and technology. The firm seeks to foster the growth of its portfolio companies from inception through to potential public exit.

Olivier Tak

Junior Partner

Mariette van der Velden

Managing Partner

11 past transactions

Avidicure

Seed Round in 2025
Avidicure is a cancer care company focused on enhancing immune system performance through innovative therapeutic approaches. The company is developing a novel class of antibodies known as AVC-Boosters, which are engineered to act as dual agonists. This multifunctional modality aims to deliver targeted and effective monotherapy, offering broad applicability in oncology. Currently operating in stealth mode, Avidicure is dedicated to pioneering advancements in cancer treatment that prioritize safety and efficacy.

Sirius Medical

Venture Round in 2025
Sirius Medical helps improve healthcare for cancer patients by developing medical devices that aid in surgical treatment. Their objective is to create intuitive and accurate gadgets that allow surgeons and radiologists to provide the finest treatment. Sirius Perception uses audio and visual feedback to provide real-time, directional advice for pinpointing tumors

Citryll

Series B in 2024
Citryll is a private pharmaceutical company based in Oss, The Netherlands, established in 2015. The company specializes in the development of pharmaceutical drugs aimed at treating autoimmune and other human diseases. Citryll's innovative approach focuses on the formation, function, and clearance of neutrophil extracellular traps (NETs) that are associated with the protein citrullination pathway, which is catalyzed by Peptidylarginine Deiminase (PAD) enzymes. This research and development are instrumental in providing treatment options for various conditions, including lupus, vasculitis, pulmonary fibrosis, rheumatoid arthritis, and organ damage resulting from sepsis.

Flindr Therapeutics

Series A in 2024
Flindr Therapeutics, a private biotech company develops next-generation precision oncology treatments.

Sirius Medical

Series B in 2023
Sirius Medical helps improve healthcare for cancer patients by developing medical devices that aid in surgical treatment. Their objective is to create intuitive and accurate gadgets that allow surgeons and radiologists to provide the finest treatment. Sirius Perception uses audio and visual feedback to provide real-time, directional advice for pinpointing tumors

Cleara Biotech

Seed Round in 2022
Cleara Biotech B.V. is a biotechnology company based in Utrecht, the Netherlands, focused on developing innovative therapeutics to selectively eliminate senescent and senescent-like cancer cells. The company specializes in creating FOXO4-based anti-senescence drugs aimed at addressing chemotoxicity and combating therapy-resistant cancer cells. Cleara Biotech's research targets a crucial aspect of cancer treatment by aiming to enhance the effectiveness of therapies and improve patient outcomes through the targeted removal of problematic cell populations.

TargED Biopharmaceuticals

Series A in 2022
TargED Biopharmaceuticals is a biotechnology company focused on developing innovative biological drugs aimed at enhancing the treatment of thrombosis. The company utilizes small antibodies, known as VhH, to deliver enzymes directly to the sites of thrombus, facilitating targeted thrombolysis. This approach allows for effective treatment regardless of the blood clot's composition, thereby enabling healthcare professionals to accelerate patient care and improve outcomes for those affected by thrombosis.

Sirius Medical

Series A in 2021
Sirius Medical helps improve healthcare for cancer patients by developing medical devices that aid in surgical treatment. Their objective is to create intuitive and accurate gadgets that allow surgeons and radiologists to provide the finest treatment. Sirius Perception uses audio and visual feedback to provide real-time, directional advice for pinpointing tumors

TargED Biopharmaceuticals

Seed Round in 2020
TargED Biopharmaceuticals is a biotechnology company focused on developing innovative biological drugs aimed at enhancing the treatment of thrombosis. The company utilizes small antibodies, known as VhH, to deliver enzymes directly to the sites of thrombus, facilitating targeted thrombolysis. This approach allows for effective treatment regardless of the blood clot's composition, thereby enabling healthcare professionals to accelerate patient care and improve outcomes for those affected by thrombosis.

Sirius Medical

Series A in 2020
Sirius Medical helps improve healthcare for cancer patients by developing medical devices that aid in surgical treatment. Their objective is to create intuitive and accurate gadgets that allow surgeons and radiologists to provide the finest treatment. Sirius Perception uses audio and visual feedback to provide real-time, directional advice for pinpointing tumors

Citryll

Series A in 2019
Citryll is a private pharmaceutical company based in Oss, The Netherlands, established in 2015. The company specializes in the development of pharmaceutical drugs aimed at treating autoimmune and other human diseases. Citryll's innovative approach focuses on the formation, function, and clearance of neutrophil extracellular traps (NETs) that are associated with the protein citrullination pathway, which is catalyzed by Peptidylarginine Deiminase (PAD) enzymes. This research and development are instrumental in providing treatment options for various conditions, including lupus, vasculitis, pulmonary fibrosis, rheumatoid arthritis, and organ damage resulting from sepsis.
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