Daiichi Sankyo Company

Daiichi Sankyo Company, Limited is a pharmaceutical firm engaged in the research, development, manufacturing, import, sale, and marketing of a diverse range of pharmaceutical products, including prescription and over-the-counter medications, as well as quasi-drugs. The company's portfolio features key products for various medical conditions, such as Olmetec and Rezaltas for cardiovascular diseases, Cravit for infectious diseases, Loxonin for bone and joint ailments, and Urief for urological issues. Additionally, Daiichi Sankyo is actively involved in vaccine development and has a pipeline of products in various stages of clinical trials. The company also manufactures cosmetics, medical equipment, food, beverages, and veterinary medicines, alongside producing active pharmaceutical ingredients. Established in 2005 from the merger of Daiichi Pharmaceuticals and Sankyo, Daiichi Sankyo operates primarily in Japan, North America, Europe, and India, with a significant focus on expanding its global presence and driving growth through its innovative antibody drug conjugates. The company is headquartered in Tokyo, Japan.

Sunao Manabe

Representative Director Executive Chairperson and CEO

10 past transactions

Cuorips

Venture Round in 2018
Cuorips Inc. is a medical care company based in Chuo, Japan, with an additional office in Osaka. Founded in 2017, the company focuses on the research, development, and commercialization of iPS cell-derived cardiomyocyte sheets and various cell therapeutic products. Cuorips is involved in the manufacturing and sales of cellular and tissue-based products, as well as providing contract development and manufacturing services. The company aims to advance medical treatments through innovative cell products and therapies.

Cuorips

Seed Round in 2017
Cuorips Inc. is a medical care company based in Chuo, Japan, with an additional office in Osaka. Founded in 2017, the company focuses on the research, development, and commercialization of iPS cell-derived cardiomyocyte sheets and various cell therapeutic products. Cuorips is involved in the manufacturing and sales of cellular and tissue-based products, as well as providing contract development and manufacturing services. The company aims to advance medical treatments through innovative cell products and therapies.

Im Co.

Acquisition in 2015
Im Co.,Ltd. manufactures and sells cosmetics and over-the-counter drugs. The company offers skin care products, including moisturizing lotions and creams, make up removers, face washes, makeup primers with sun protection, and lip moisturizing treatments; and beauty supplements.

Ambit Biosciences

Acquisition in 2014
Ambit Biosciences is a privately-held biopharmaceutical company engaged in the discovery and development of small molecule kinase inhibitors for the treatment of cancer, inflammatory disease, and other indications. Ambit's lead compound, AC220, is a novel, potent, highly selective, orally bioavailable FMS-like tyrosine kinase-3 (FLT3) inhibitor, and is currently under clinical investigation in patients with relapsed or refractory AML. Ambit is developing AC220 in collaboration with Astellas Pharma Inc. as part of a worldwide agreement to jointly develop and commercialize FLT3 kinase inhibitors in oncology and non-oncology indications. In addition to AC220, Ambit's clinical pipeline includes AC480, a pan-HER inhibitor, and AC430, an oral JAK2 inhibitor. Ambit also has a pipeline of preclinical candidates which includes CEP-32496, a BRAF inhibitor licensed to Cephalon.

Orphan Disease Treatment Institute

Pre Seed Round in 2013
Orphan Disease Treatment Institute develops a treatment for Duchenne muscular dystrophy.

Coherus Biosciences

Series B in 2012
Coherus Biosciences is a biopharmaceutical company that specializes in the development, manufacture, and commercialization of biologic therapeutics, with a strong emphasis on oncology and inflammatory diseases. The company is actively engaged in research and development, focusing on process science, analytical characterization, and protein production. Coherus's portfolio includes FDA-approved products such as UDENYCA, a biosimilar of Neulasta, and it plans to launch YUSIMRY, a biosimilar of Humira, in the United States. Additionally, the company is advancing a pipeline of biosimilar candidates across areas such as immunology and ophthalmology, as well as anti-tumor necrosis factor treatments. With a commitment to building an immuno-oncology franchise, Coherus aims to leverage its diversified portfolio to generate revenue and enhance patient access to biologic therapies.

Plexxikon

Acquisition in 2011
Plexxikon, Inc. is a biopharmaceutical company focused on the discovery and development of small molecule pharmaceuticals aimed at treating various human diseases. The company has developed several products, including PLX204 for diabetes and PLX4032 for melanoma and colorectal cancer. Additionally, it is advancing PLX5568 kinase inhibitors for conditions such as pain, polycystic kidney disease, rheumatoid arthritis, metastatic breast cancer, and renal disease. Plexxikon's research encompasses a diverse portfolio of clinical and preclinical programs across multiple therapeutic areas, including metabolic diseases like obesity, oncology targeting osteolytic metastatic disease, and central nervous system disorders such as multiple sclerosis. The company is also exploring treatments for inflammation-related conditions and cardiovascular diseases.

Ranbaxy Laboratories

Acquisition in 2008
Ranbaxy Laboratories Limited is a pharmaceutical company established in 1961, specializing in the production of quality and affordable generic medicines. The company operates in 49 countries with manufacturing facilities in 11 countries, serving customers across approximately 125 countries. Ranbaxy's extensive product portfolio includes around 5,000 stock-keeping units (SKUs) that cover a wide range of therapeutic areas for both chronic and acute conditions. The company focuses on value-added formulations and has developed several Novel Drug Delivery Systems (NDDS) aimed at enhancing drug efficacy, particularly in oral controlled-release products. Additionally, Ranbaxy engages in New Drug Discovery Research (NDDR) targeting various therapeutic segments, including infectious diseases, metabolic diseases, and oncology. The company has several ongoing research programs and has established collaborations with academic institutions to explore novel pharmaceutical agents. Notably, Ranbaxy formed a strategic alliance with Daiichi Sankyo in 2008 to strengthen its position in the generic pharmaceutical market and has entered into agreements for products such as Neuronox, a botulinum toxin for cosmetic use.

U3 Pharma

Acquisition in 2008
U3 Pharma GmbH, based in Martinsried near Munich, Germany, is a leader in targeted cancer drug development. Established in July 2001, the company has produced a pipeline of novel targeted therapeutics based on the ground-breaking discoveries made by its founder - Professor Axel Ullrich. Since May 2008 U3 Pharma belongs to DAIICHI Sankyo Co. Ltd., one of the top 20 leading pharmaceutical companies worldwide and no. 3 in Japan. Being part of this global environment, U3 Pharma is striving to provide patients around the world with innovative antibody-based therapeutics.

SymBio Pharmaceuticals

Series A in 2005
SymBio Pharmaceuticals Limited operates as a biopharmaceutical company. It offers Symbenda medicine for treating low-grade non-Hodgkin's lymphoma and chronic lymphatic leukemia in Singapore. The company was founded in 2005 and is headquartered in Tokyo, Japan.
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