Define Ventures

Define Ventures is an early-stage venture capital firm based in San Francisco, California, founded in 2019. The firm specializes in investing exclusively in digital health companies, aiming to support entrepreneurs who are dedicated to transforming healthcare through innovative digital solutions. By partnering with these entrepreneurs, Define Ventures seeks to leverage their expertise and insights to redefine the healthcare landscape.

Chuka Esiobu

Senior Associate

Garrett Howard

Senior Associate and Investor

Lynne Chou O'Keefe

Founder and Managing Partner

Chirag Shah

Partner

Hong Truong

Principal

Frank Williams

Venture Partner

46 past transactions

Marit Health

Seed Round in 2025
Marit Health is a digital platform designed to empower clinicians in their career progression. It facilitates anonymous, verified salary sharing among healthcare professionals, providing detailed insights into compensation by specialty and location. This includes data on salaries, bonuses, benefits, and shifts, enabling clinicians to make more informed career decisions.

Layer Health

Series A in 2025
Layer Health is a technology company specializing in AI-driven healthcare information solutions. It develops an AI-powered platform designed to help healthcare providers extract valuable insights from patient data, enabling them to make informed decisions, enhance patient care, and improve operational efficiency. The platform focuses on processing unstructured data from clinical, administrative, and research sources, transforming it into actionable insights.

Soda Health

Series B in 2024
Soda Health, established in 2021 with its headquarters in Chicago, Illinois, is a healthcare technology company focused on reducing health disparities by addressing social determinants of health. The company operates a platform designed to help individuals identify, access, and afford necessary resources for leading healthier lives. This platform facilitates personalized benefit administration and reimbursement, bridging the gap between medical claims and retail payments more cost-effectively than traditional methods.

Blackbird Health

Series A in 2024
Blackbird Health is a mental health clinic specializing in supporting children and young adults facing social, developmental, and academic challenges. It offers both in-person and virtual therapy sessions, ensuring accessibility for a wider range of clients. The clinic takes a holistic approach to mental health care, aiming to address the overall well-being of its clients by combining innovative technology and interdisciplinary teams for accurate diagnosis and efficient treatment.

9amHealth

Series A in 2024
9amHealth is a healthcare service provider that aims to deliver comprehensive medical support for chronic conditions such as diabetes, hypertension, and hyperlipidemia. The company offers personalized care plans, prescription medication, at-home lab tests, and unlimited virtual visits, ensuring that patients have direct access to affordable and compassionate care. By redesigning all care elements into a single digital service, 9amHealth caters to the modern realities of patients' lives, making healthcare always available and convenient, even for those without insurance. Its focus on chronic conditions highlights its commitment to improving the health and well-being of customers in the United States.

Cohere Health

Series C in 2024
Cohere Health, Inc. is a healthcare technology company based in Boston, Massachusetts, founded in 2019. The company specializes in developing a platform that enhances collaboration among healthcare stakeholders, including patients, providers, and payers. Cohere Health focuses on improving the efficiency and effectiveness of healthcare delivery by simplifying complex processes through technology. Its primary offering is an intelligent prior authorization solution that is configurable to meet the specific needs of different health plans. This solution can be implemented as a fully outsourced utilization management service, utilizing artificial intelligence, machine learning, and real-time analytics to automate the prior authorization process. By doing so, Cohere Health aims to facilitate seamless communication and guide quality care throughout the patient journey, ultimately improving patient outcomes.

Datalogz

Series A in 2023
Datalogz is a company that specializes in a platform designed for data discovery and understanding, focused on reducing data ambiguity from various sources. Its platform offers a suite of features, including a data catalog, data lineage, data governance, and a data glossary. These tools empower data scientists and analysts to utilize AI-driven recommendations, thereby enhancing project quality and minimizing inefficiencies in workflows. By streamlining the data management process, Datalogz aims to facilitate better decision-making and foster a clearer understanding of data across organizations.

RepubliK GG

Seed Round in 2023
RepubliK GG specializes in developing a suite of tools for creators. It helps creators to unlock a wealth of untapped opportunities that cannot be reached within the confines of current social platforms.

DexCare

Series C in 2023
DexCare is a Seattle-based company founded in 2021 that specializes in providing a platform-as-a-service solution for managing health system capacity and demand across various lines of care. The company's platform aims to transform traditional patient-to-provider relationships into scalable digital experiences, thereby increasing revenue from new patients while reducing acquisition costs. By optimizing access to healthcare services, DexCare helps healthcare institutions generate new patients, enhance satisfaction, achieve cost savings, and ensure that patients receive timely and effective care.

Laudio

Series B in 2023
Laudio LLC is a Boston-based company that offers a software-as-a-service platform focused on healthcare leadership and staff relationship management. Established in 2017, Laudio's platform employs artificial intelligence and predictive analytics to enhance employee engagement and retention while minimizing burnout. It provides healthcare executives and managers with an integrated management system that facilitates timely interactions with staff, digitizes workflows, and suggests proactive interventions based on individual risk factors for turnover. By streamlining processes and improving communication, Laudio aims to help healthcare organizations reduce turnover costs and foster a more engaged workforce.

Intrinsic

Venture Round in 2023
Intrinsic Brands is an eCommerce acquisition and growth platform uniquely focused on digital-first health and wellness brands.

Crescendo Health

Seed Round in 2023
Crescendo Health is a digital health company focused on revolutionizing the collection and utilization of patient health data to enhance clinical research. By fostering relationships with patients and obtaining their consent, Crescendo Health collects and curates health information, offering trial sponsors a comprehensive and longitudinal perspective on patient health. Founded by experienced healthcare executives from notable organizations, Crescendo Health combines expertise from various sectors, including research, technology, and healthcare, to create a platform that facilitates the assembly of individuals' health narratives while ensuring privacy protection. Patients have the option to retain access to their personal health records or request their data be deleted, with all information securely stored in a cloud-based database. This approach allows researchers and clinicians to gain deeper insights into health journeys, ultimately contributing to the development of more effective clinical trials.

UpStream Care

Series B in 2022
UpStream Care is a primary care services and technology company providing physicians with support and systems. It allows physicians to focus on what they and their patients value the most. Their intelligent technology platform, which integrates with all physician EMRs and provides an elegant workflow for all care coordination activities, augments this in-person clinical support.

FOLX

Series B in 2022
Folx Health is a telehealth platform established in 2020, based in Boston, Massachusetts, that specializes in providing digital healthcare services for the LGBTQIA+ community. The company focuses on creating a medical service marketplace tailored to the needs of queer and trans individuals, offering access to a network of specialized clinicians. Folx Health's services include gender-affirming hormone therapy, sexual health care, fertility testing, and general medical services. The platform emphasizes discreet delivery of at-home kits for medications, labs, and supplies, enabling users to manage their health without the barriers and stigma often found in traditional healthcare settings.

Soda Health

Series A in 2022
Soda Health, established in 2021 with its headquarters in Chicago, Illinois, is a healthcare technology company focused on reducing health disparities by addressing social determinants of health. The company operates a platform designed to help individuals identify, access, and afford necessary resources for leading healthier lives. This platform facilitates personalized benefit administration and reimbursement, bridging the gap between medical claims and retail payments more cost-effectively than traditional methods.

Fair Square Medicare

Series A in 2022
Fair Square Medicare is a company dedicated to simplifying the process of purchasing health insurance for seniors. It offers a personalized Medicare guide that aggregates various health insurance plans based on the client's zip code, utilizing data sourced directly from the Centers for Medicare Services (CMS). The company's systematic software analyzes available plans to identify the most relevant options for customers. Once the options are narrowed down, licensed partner agents assist clients in understanding the benefits and drawbacks of each plan, ensuring they make informed decisions about their healthcare coverage.

Concert Health

Series B in 2022
Concert Health, Inc. is a San Diego-based company that operates an integrated online platform designed to facilitate collaboration between primary care providers and behavioral health specialists. Founded in 2016, the company assists medical groups in incorporating behavioral health services such as screening, therapy, and psychiatric consultations into their practices. Concert Health offers a range of services, including remote clinical staffing with behavioral care managers and psychiatric consultants, as well as tools for registry, workflow management, and reimbursement support. By working directly with primary care teams, Concert Health develops shared care plans that address both physical and mental health conditions, ensuring the delivery of high-quality, evidence-based behavioral health care.

Waltz Health

Series A in 2022
Waltz Health is a company focused on innovating the pharmaceutical supply chain by developing technology-driven solutions for pricing, distribution, and prescription of medications. It collaborates with various partners, including consumers, payers, and pharmacies, to create smarter ways to manage prescription care. The company utilizes AI-driven marketplaces to reduce costs and offers consumer tools that enhance decision-making regarding healthcare. These tools provide users with better pricing, comprehensive information, and resources aimed at lowering expenses, empowering consumers, and enabling payers to effectively manage their pharmacy benefits. Through these efforts, Waltz Health strives to improve the overall experience and affordability of prescription medications.

9amHealth

Series A in 2022
9amHealth is a healthcare service provider that aims to deliver comprehensive medical support for chronic conditions such as diabetes, hypertension, and hyperlipidemia. The company offers personalized care plans, prescription medication, at-home lab tests, and unlimited virtual visits, ensuring that patients have direct access to affordable and compassionate care. By redesigning all care elements into a single digital service, 9amHealth caters to the modern realities of patients' lives, making healthcare always available and convenient, even for those without insurance. Its focus on chronic conditions highlights its commitment to improving the health and well-being of customers in the United States.

Story Health

Series A in 2022
Story Health Corporation is a healthcare technology company founded in 2020 and based in Saratoga, California. The company develops intelligent embedded virtualized clinical care software tools designed to assist healthcare specialists, including neurologists and primary care physicians, in understanding medical situations and making informed clinical decisions. Story Health's platform utilizes data from high-frequency sources to enhance therapy management through virtual protocols and adaptive machine learning. By focusing on patient-centered design, Story Health aims to bridge the gap between clinical evidence and real-world patient experiences, enabling clinicians to effectively address the physiological effects of disease and therapy.

DexCare

Series B in 2022
DexCare is a Seattle-based company founded in 2021 that specializes in providing a platform-as-a-service solution for managing health system capacity and demand across various lines of care. The company's platform aims to transform traditional patient-to-provider relationships into scalable digital experiences, thereby increasing revenue from new patients while reducing acquisition costs. By optimizing access to healthcare services, DexCare helps healthcare institutions generate new patients, enhance satisfaction, achieve cost savings, and ensure that patients receive timely and effective care.

Found

Series B in 2021
Found is dedicated to improving people’s overall wellbeing by making evidence-based weight loss accessible and affordable. The company was founded in 2019 and is headquartered in San Francisco, California, United States.

MedArrive

Series A in 2021
MedArrive, Inc. is a New York-based company that operates a software-as-a-service health platform designed to enhance care management by connecting healthcare providers with patients in their homes. The platform integrates clinical data into electronic medical records and facilitates communication and billing processes. By utilizing emergency medical services professionals, MedArrive enables healthcare providers to deliver high-quality care at home, improving access for vulnerable populations while reducing overall healthcare costs. This innovative approach fosters patient self-advocacy and continuity of care, helping to re-engage patients in primary care and enhance health outcomes. MedArrive's technology and holistic care model represent a strategic effort to bridge the gap between virtual care and in-person support, ultimately benefiting both patients and healthcare providers.

Lightship

Series C in 2021
Lightship is a company founded in 2018 that focuses on transforming clinical trials to enhance health equity globally. By leveraging digital health innovations and remote care, it aims to make clinical research more accessible and patient-centered. Lightship provides decentralized and hybrid clinical services that improve patient experience, retention, and trial diversity. Its approach expands the pool of potential participants by moving beyond traditional research centers, effectively meeting patients in their own environments. This strategy helps to eliminate the barriers and inefficiencies associated with conventional clinical trial models, ultimately making medical research more inclusive and effective.

Centivo

Venture Round in 2021
Centivo Corporation is a health insurance provider that specializes in offering innovative health plans for self-funded employers, employees, and clinicians. Established in 2016 and headquartered in Stamford, Connecticut, with additional offices in New York and Buffalo, Centivo serves as an alternative to traditional insurance carriers and third-party administrators. The company integrates technology, network management, claims processing, and customer support to effectively administer health benefits. Centivo emphasizes collaboration between employees and their primary care teams to coordinate healthcare needs, encouraging members to engage in high-value care through personalized matching tools and a user-friendly app. By focusing on controlling costs and improving navigation through the healthcare system, Centivo positions itself as a dedicated partner to employers, ensuring accountability and minimizing waste in healthcare spending.

9amHealth

Seed Round in 2021
9amHealth is a healthcare service provider that aims to deliver comprehensive medical support for chronic conditions such as diabetes, hypertension, and hyperlipidemia. The company offers personalized care plans, prescription medication, at-home lab tests, and unlimited virtual visits, ensuring that patients have direct access to affordable and compassionate care. By redesigning all care elements into a single digital service, 9amHealth caters to the modern realities of patients' lives, making healthcare always available and convenient, even for those without insurance. Its focus on chronic conditions highlights its commitment to improving the health and well-being of customers in the United States.

Tia

Series B in 2021
Tia, Inc. is a health advisory platform focused on providing personalized and data-driven healthcare solutions for women. Founded in 2015 and headquartered in New York, with an additional location in San Francisco, Tia offers a mobile application that features a range of services including birth control recommendations, sexual health advice, symptom tracking, and doctor locators. The platform empowers women to make informed decisions about their health by facilitating access to both in-office appointments and virtual care. Recognizing that traditional healthcare systems often overlook women's needs, Tia aims to create a distinctly female-centered model of care that addresses the unique healthcare challenges women face.

Soda Health

Seed Round in 2021
Soda Health, established in 2021 with its headquarters in Chicago, Illinois, is a healthcare technology company focused on reducing health disparities by addressing social determinants of health. The company operates a platform designed to help individuals identify, access, and afford necessary resources for leading healthier lives. This platform facilitates personalized benefit administration and reimbursement, bridging the gap between medical claims and retail payments more cost-effectively than traditional methods.

Intrinsic

Series A in 2021
Intrinsic Brands is an eCommerce acquisition and growth platform uniquely focused on digital-first health and wellness brands.

Cohere Health

Series B in 2021
Cohere Health, Inc. is a healthcare technology company based in Boston, Massachusetts, founded in 2019. The company specializes in developing a platform that enhances collaboration among healthcare stakeholders, including patients, providers, and payers. Cohere Health focuses on improving the efficiency and effectiveness of healthcare delivery by simplifying complex processes through technology. Its primary offering is an intelligent prior authorization solution that is configurable to meet the specific needs of different health plans. This solution can be implemented as a fully outsourced utilization management service, utilizing artificial intelligence, machine learning, and real-time analytics to automate the prior authorization process. By doing so, Cohere Health aims to facilitate seamless communication and guide quality care throughout the patient journey, ultimately improving patient outcomes.

DexCare

Series A in 2021
DexCare is a Seattle-based company founded in 2021 that specializes in providing a platform-as-a-service solution for managing health system capacity and demand across various lines of care. The company's platform aims to transform traditional patient-to-provider relationships into scalable digital experiences, thereby increasing revenue from new patients while reducing acquisition costs. By optimizing access to healthcare services, DexCare helps healthcare institutions generate new patients, enhance satisfaction, achieve cost savings, and ensure that patients receive timely and effective care.

Unite Us

Series C in 2021
Unite Us is a veteran-led technology company founded in 2013 in New York, specializing in creating coordinated care networks that connect health and social service providers. The company develops a platform that enables providers to send and receive secure referrals, track individuals' health journeys, and report on outcomes across a variety of services. By integrating social determinants of health into patient care, Unite Us facilitates a cohesive and collaborative ecosystem that enhances the ability of communities to deliver services effectively. This innovative approach moves beyond traditional resource directories, allowing systems to measure impact and improve health outcomes on a larger scale.

FOLX

Series A in 2021
Folx Health is a telehealth platform established in 2020, based in Boston, Massachusetts, that specializes in providing digital healthcare services for the LGBTQIA+ community. The company focuses on creating a medical service marketplace tailored to the needs of queer and trans individuals, offering access to a network of specialized clinicians. Folx Health's services include gender-affirming hormone therapy, sexual health care, fertility testing, and general medical services. The platform emphasizes discreet delivery of at-home kits for medications, labs, and supplies, enabling users to manage their health without the barriers and stigma often found in traditional healthcare settings.

Found

Series A in 2021
Found is dedicated to improving people’s overall wellbeing by making evidence-based weight loss accessible and affordable. The company was founded in 2019 and is headquartered in San Francisco, California, United States.

Story Health

Seed Round in 2020
Story Health Corporation is a healthcare technology company founded in 2020 and based in Saratoga, California. The company develops intelligent embedded virtualized clinical care software tools designed to assist healthcare specialists, including neurologists and primary care physicians, in understanding medical situations and making informed clinical decisions. Story Health's platform utilizes data from high-frequency sources to enhance therapy management through virtual protocols and adaptive machine learning. By focusing on patient-centered design, Story Health aims to bridge the gap between clinical evidence and real-world patient experiences, enabling clinicians to effectively address the physiological effects of disease and therapy.

Centivo

Series B in 2020
Centivo Corporation is a health insurance provider that specializes in offering innovative health plans for self-funded employers, employees, and clinicians. Established in 2016 and headquartered in Stamford, Connecticut, with additional offices in New York and Buffalo, Centivo serves as an alternative to traditional insurance carriers and third-party administrators. The company integrates technology, network management, claims processing, and customer support to effectively administer health benefits. Centivo emphasizes collaboration between employees and their primary care teams to coordinate healthcare needs, encouraging members to engage in high-value care through personalized matching tools and a user-friendly app. By focusing on controlling costs and improving navigation through the healthcare system, Centivo positions itself as a dedicated partner to employers, ensuring accountability and minimizing waste in healthcare spending.

MedArrive

Seed Round in 2020
MedArrive, Inc. is a New York-based company that operates a software-as-a-service health platform designed to enhance care management by connecting healthcare providers with patients in their homes. The platform integrates clinical data into electronic medical records and facilitates communication and billing processes. By utilizing emergency medical services professionals, MedArrive enables healthcare providers to deliver high-quality care at home, improving access for vulnerable populations while reducing overall healthcare costs. This innovative approach fosters patient self-advocacy and continuity of care, helping to re-engage patients in primary care and enhance health outcomes. MedArrive's technology and holistic care model represent a strategic effort to bridge the gap between virtual care and in-person support, ultimately benefiting both patients and healthcare providers.

Cohere Health

Series A in 2020
Cohere Health, Inc. is a healthcare technology company based in Boston, Massachusetts, founded in 2019. The company specializes in developing a platform that enhances collaboration among healthcare stakeholders, including patients, providers, and payers. Cohere Health focuses on improving the efficiency and effectiveness of healthcare delivery by simplifying complex processes through technology. Its primary offering is an intelligent prior authorization solution that is configurable to meet the specific needs of different health plans. This solution can be implemented as a fully outsourced utilization management service, utilizing artificial intelligence, machine learning, and real-time analytics to automate the prior authorization process. By doing so, Cohere Health aims to facilitate seamless communication and guide quality care throughout the patient journey, ultimately improving patient outcomes.

Tia

Series A in 2020
Tia, Inc. is a health advisory platform focused on providing personalized and data-driven healthcare solutions for women. Founded in 2015 and headquartered in New York, with an additional location in San Francisco, Tia offers a mobile application that features a range of services including birth control recommendations, sexual health advice, symptom tracking, and doctor locators. The platform empowers women to make informed decisions about their health by facilitating access to both in-office appointments and virtual care. Recognizing that traditional healthcare systems often overlook women's needs, Tia aims to create a distinctly female-centered model of care that addresses the unique healthcare challenges women face.

FOLX

Venture Round in 2020
Folx Health is a telehealth platform established in 2020, based in Boston, Massachusetts, that specializes in providing digital healthcare services for the LGBTQIA+ community. The company focuses on creating a medical service marketplace tailored to the needs of queer and trans individuals, offering access to a network of specialized clinicians. Folx Health's services include gender-affirming hormone therapy, sexual health care, fertility testing, and general medical services. The platform emphasizes discreet delivery of at-home kits for medications, labs, and supplies, enabling users to manage their health without the barriers and stigma often found in traditional healthcare settings.

Found

Seed Round in 2020
Found is dedicated to improving people’s overall wellbeing by making evidence-based weight loss accessible and affordable. The company was founded in 2019 and is headquartered in San Francisco, California, United States.

Verana Health

Series D in 2020
Verana Health, Inc. is a digital health company based in San Francisco, California, that specializes in transforming healthcare data into actionable insights. Founded in 2008 and formerly known as Digisight Technologies, the company connects healthcare providers with patients through innovative solutions. Its flagship product, SightBook, is a mobile application that enables users to test their vision and share results with their physicians in real-time, facilitating timely appointments and treatments. Verana Health manages data from over 20,000 healthcare providers and 70 electronic health record systems, leveraging its AI-enhanced platform, VeraQ™, to create a robust healthcare data ecosystem. By utilizing advanced analytics on curated datasets, Verana Health supports life sciences partners in improving clinical research and enhancing patient care outcomes.

Lightship

Series B in 2020
Lightship is a company founded in 2018 that focuses on transforming clinical trials to enhance health equity globally. By leveraging digital health innovations and remote care, it aims to make clinical research more accessible and patient-centered. Lightship provides decentralized and hybrid clinical services that improve patient experience, retention, and trial diversity. Its approach expands the pool of potential participants by moving beyond traditional research centers, effectively meeting patients in their own environments. This strategy helps to eliminate the barriers and inefficiencies associated with conventional clinical trial models, ultimately making medical research more inclusive and effective.

Unite Us

Series B in 2019
Unite Us is a veteran-led technology company founded in 2013 in New York, specializing in creating coordinated care networks that connect health and social service providers. The company develops a platform that enables providers to send and receive secure referrals, track individuals' health journeys, and report on outcomes across a variety of services. By integrating social determinants of health into patient care, Unite Us facilitates a cohesive and collaborative ecosystem that enhances the ability of communities to deliver services effectively. This innovative approach moves beyond traditional resource directories, allowing systems to measure impact and improve health outcomes on a larger scale.

Tia

Seed Round in 2019
Tia, Inc. is a health advisory platform focused on providing personalized and data-driven healthcare solutions for women. Founded in 2015 and headquartered in New York, with an additional location in San Francisco, Tia offers a mobile application that features a range of services including birth control recommendations, sexual health advice, symptom tracking, and doctor locators. The platform empowers women to make informed decisions about their health by facilitating access to both in-office appointments and virtual care. Recognizing that traditional healthcare systems often overlook women's needs, Tia aims to create a distinctly female-centered model of care that addresses the unique healthcare challenges women face.

Cohere Health

Cohere Health, Inc. is a healthcare technology company based in Boston, Massachusetts, founded in 2019. The company specializes in developing a platform that enhances collaboration among healthcare stakeholders, including patients, providers, and payers. Cohere Health focuses on improving the efficiency and effectiveness of healthcare delivery by simplifying complex processes through technology. Its primary offering is an intelligent prior authorization solution that is configurable to meet the specific needs of different health plans. This solution can be implemented as a fully outsourced utilization management service, utilizing artificial intelligence, machine learning, and real-time analytics to automate the prior authorization process. By doing so, Cohere Health aims to facilitate seamless communication and guide quality care throughout the patient journey, ultimately improving patient outcomes.
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