Define Ventures

Define Ventures is an early-stage venture capital firm based in San Francisco that concentrates on digital health and healthcare technology. Founded in 2019, the firm invests in startups developing digital health solutions and related healthcare tech, aiming to accelerate product development and market adoption. It partners with founders who bring specialized digital health expertise to redefine healthcare, providing support to help early-stage companies scale and navigate regulatory and market challenges.

Kristi Ebong

Investor

Chuka Esiobu

Investor

Garrett Howard

Senior Associate and Investor

Lynne Chou O’Keefe

Managing Partner

Chirag Shah

Partner

Hong Truong

Principal

Frank Williams

Venture Partner

46 past transactions

Marit Health

Seed Round in 2025
Marit Health is a digital platform designed to empower clinicians in their career progression. It facilitates anonymous, verified salary sharing among healthcare professionals, providing detailed insights into compensation by specialty and location. This includes data on salaries, bonuses, benefits, and shifts, enabling clinicians to make more informed career decisions.

Layer Health

Series A in 2025
Layer Health is a technology company specializing in AI-driven healthcare information solutions. It develops an AI-powered platform designed to help healthcare providers extract valuable insights from patient data, enabling them to make informed decisions, enhance patient care, and improve operational efficiency. The platform focuses on processing unstructured data from clinical, administrative, and research sources, transforming it into actionable insights.

Soda Health

Series B in 2024
Founded in 2021, Soda Health is a Chicago-based healthcare technology company committed to reducing health disparities by addressing social determinants of health. It operates a platform that delivers personalized benefits, providing real-time access to essential services such as healthy food, over-the-counter medications, and transportation.

Blackbird Health

Series A in 2024
Blackbird Health is a mental health clinic specializing in supporting children and young adults facing social, developmental, and academic challenges. It offers both in-person and virtual therapy sessions, ensuring accessibility for a wider range of clients. The clinic takes a holistic approach to mental health care, aiming to address the overall well-being of its clients by combining innovative technology and interdisciplinary teams for accurate diagnosis and efficient treatment.

9amHealth

Series A in 2024
9amHealth is a healthcare service provider that aims to deliver comprehensive medical support for chronic conditions such as diabetes, hypertension, and hyperlipidemia. The company offers personalized care plans, prescription medication, at-home lab tests, and unlimited virtual visits, ensuring that patients have direct access to affordable and compassionate care. By redesigning all care elements into a single digital service, 9amHealth caters to the modern realities of patients' lives, making healthcare always available and convenient, even for those without insurance. Its focus on chronic conditions highlights its commitment to improving the health and well-being of customers in the United States.

Cohere Health

Series C in 2024
Founded in 2019 and based in Boston, Cohere Health is a healthcare technology company dedicated to enhancing efficiency and effectiveness within the healthcare system. It achieves this by leveraging technology to simplify processes, improve communication among stakeholders, and ultimately optimize patient outcomes.

Datalogz

Series A in 2023
Datalogz is a company that specializes in a platform designed for data discovery and understanding, focused on reducing data ambiguity from various sources. Its platform offers a suite of features, including a data catalog, data lineage, data governance, and a data glossary. These tools empower data scientists and analysts to utilize AI-driven recommendations, thereby enhancing project quality and minimizing inefficiencies in workflows. By streamlining the data management process, Datalogz aims to facilitate better decision-making and foster a clearer understanding of data across organizations.

RepubliK GG

Seed Round in 2023
RepubliK GG specializes in developing a suite of tools for creators. It helps creators to unlock a wealth of untapped opportunities that cannot be reached within the confines of current social platforms.

DexCare

Series C in 2023
DexCare is a Seattle-based company founded in 2021 that specializes in providing a platform-as-a-service solution for managing health system capacity and demand across various lines of care. The company's platform aims to transform traditional patient-to-provider relationships into scalable digital experiences, thereby increasing revenue from new patients while reducing acquisition costs. By optimizing access to healthcare services, DexCare helps healthcare institutions generate new patients, enhance satisfaction, achieve cost savings, and ensure that patients receive timely and effective care.

Laudio

Series B in 2023
Laudio LLC is a Boston-based company that offers a software-as-a-service platform focused on healthcare leadership and staff relationship management. Established in 2017, Laudio's platform employs artificial intelligence and predictive analytics to enhance employee engagement and retention while minimizing burnout. It provides healthcare executives and managers with an integrated management system that facilitates timely interactions with staff, digitizes workflows, and suggests proactive interventions based on individual risk factors for turnover. By streamlining processes and improving communication, Laudio aims to help healthcare organizations reduce turnover costs and foster a more engaged workforce.

Intrinsic

Venture Round in 2023
Intrinsic Brands is an eCommerce acquisition and growth platform uniquely focused on digital-first health and wellness brands.

Crescendo Health

Seed Round in 2023
Crescendo Health is a digital health company that collects and curates patient health data for clinical research. It builds relationships with patients, gaining consent to gather health information securely, providing trial sponsors with comprehensive longitudinal views of patient health.

UpStream Care

Series B in 2022
UpStream Care is a primary care services and technology company providing physicians with support and systems. It allows physicians to focus on what they and their patients value the most. Their intelligent technology platform, which integrates with all physician EMRs and provides an elegant workflow for all care coordination activities, augments this in-person clinical support.

Folx Health

Series B in 2022
Folx Health is a Boston-based telehealth platform founded in 2020, specializing in digital healthcare services tailored for the LGBTQIA+ community. It offers access to queer and trans clinicians, focusing on gender-affirming hormone therapy, sexual health, and family creation services.

Soda Health

Series A in 2022
Founded in 2021, Soda Health is a Chicago-based healthcare technology company committed to reducing health disparities by addressing social determinants of health. It operates a platform that delivers personalized benefits, providing real-time access to essential services such as healthy food, over-the-counter medications, and transportation.

Fair Square Medicare

Series A in 2022
Fair Square Medicare is a company dedicated to simplifying the process of purchasing health insurance for seniors. It offers a personalized Medicare guide that aggregates various health insurance plans based on the client's zip code, utilizing data sourced directly from the Centers for Medicare Services (CMS). The company's systematic software analyzes available plans to identify the most relevant options for customers. Once the options are narrowed down, licensed partner agents assist clients in understanding the benefits and drawbacks of each plan, ensuring they make informed decisions about their healthcare coverage.

Concert Health

Series B in 2022
Founded in 2016, Concert Health operates an online platform that connects patients with therapists and psychiatrists through their primary care providers. The company offers remote clinical staffing, screening tools, implementation guidance, documentation support, and evidence-based care integration to facilitate behavioral health services within medical practices.

Waltz Health

Series A in 2022
Waltz Health is a company focused on innovating the pharmaceutical supply chain by developing technology-driven solutions for pricing, distribution, and prescription of medications. It collaborates with various partners, including consumers, payers, and pharmacies, to create smarter ways to manage prescription care. The company utilizes AI-driven marketplaces to reduce costs and offers consumer tools that enhance decision-making regarding healthcare. These tools provide users with better pricing, comprehensive information, and resources aimed at lowering expenses, empowering consumers, and enabling payers to effectively manage their pharmacy benefits. Through these efforts, Waltz Health strives to improve the overall experience and affordability of prescription medications.

9amHealth

Series A in 2022
9amHealth is a healthcare service provider that aims to deliver comprehensive medical support for chronic conditions such as diabetes, hypertension, and hyperlipidemia. The company offers personalized care plans, prescription medication, at-home lab tests, and unlimited virtual visits, ensuring that patients have direct access to affordable and compassionate care. By redesigning all care elements into a single digital service, 9amHealth caters to the modern realities of patients' lives, making healthcare always available and convenient, even for those without insurance. Its focus on chronic conditions highlights its commitment to improving the health and well-being of customers in the United States.

Story Health

Series A in 2022
Story Health Corporation is a healthcare technology company founded in 2020 and based in Saratoga, California. The company develops intelligent embedded virtualized clinical care software tools designed to assist healthcare specialists, including neurologists and primary care physicians, in understanding medical situations and making informed clinical decisions. Story Health's platform utilizes data from high-frequency sources to enhance therapy management through virtual protocols and adaptive machine learning. By focusing on patient-centered design, Story Health aims to bridge the gap between clinical evidence and real-world patient experiences, enabling clinicians to effectively address the physiological effects of disease and therapy.

DexCare

Series B in 2022
DexCare is a Seattle-based company founded in 2021 that specializes in providing a platform-as-a-service solution for managing health system capacity and demand across various lines of care. The company's platform aims to transform traditional patient-to-provider relationships into scalable digital experiences, thereby increasing revenue from new patients while reducing acquisition costs. By optimizing access to healthcare services, DexCare helps healthcare institutions generate new patients, enhance satisfaction, achieve cost savings, and ensure that patients receive timely and effective care.

Found

Series B in 2021
Found is dedicated to improving people’s overall wellbeing by making evidence-based weight loss accessible and affordable. The company was founded in 2019 and is headquartered in San Francisco, California, United States.

MedArrive

Series A in 2021
MedArrive, Inc. is a New York-based company that operates a software-as-a-service health platform designed to enhance care management by connecting healthcare providers with patients in their homes. The platform integrates clinical data into electronic medical records and facilitates communication and billing processes. By utilizing emergency medical services professionals, MedArrive enables healthcare providers to deliver high-quality care at home, improving access for vulnerable populations while reducing overall healthcare costs. This innovative approach fosters patient self-advocacy and continuity of care, helping to re-engage patients in primary care and enhance health outcomes. MedArrive's technology and holistic care model represent a strategic effort to bridge the gap between virtual care and in-person support, ultimately benefiting both patients and healthcare providers.

Lightship

Series C in 2021
Founded in 2018, Lightship aims to enhance health equity globally by transforming clinical trials. It combines digital health innovations, technology, remote care, and high-quality clinical research to make studies more accessible and offer choices, keeping patients at the core of its work.

Centivo

Venture Round in 2021
Centivo Corporation is a health insurance provider that specializes in offering innovative health plans for self-funded employers, employees, and clinicians. Established in 2016 and headquartered in Stamford, Connecticut, with additional offices in New York and Buffalo, Centivo serves as an alternative to traditional insurance carriers and third-party administrators. The company integrates technology, network management, claims processing, and customer support to effectively administer health benefits. Centivo emphasizes collaboration between employees and their primary care teams to coordinate healthcare needs, encouraging members to engage in high-value care through personalized matching tools and a user-friendly app. By focusing on controlling costs and improving navigation through the healthcare system, Centivo positions itself as a dedicated partner to employers, ensuring accountability and minimizing waste in healthcare spending.

9amHealth

Seed Round in 2021
9amHealth is a healthcare service provider that aims to deliver comprehensive medical support for chronic conditions such as diabetes, hypertension, and hyperlipidemia. The company offers personalized care plans, prescription medication, at-home lab tests, and unlimited virtual visits, ensuring that patients have direct access to affordable and compassionate care. By redesigning all care elements into a single digital service, 9amHealth caters to the modern realities of patients' lives, making healthcare always available and convenient, even for those without insurance. Its focus on chronic conditions highlights its commitment to improving the health and well-being of customers in the United States.

Tia

Series B in 2021
Tia, Inc. is a health advisory platform focused on providing personalized and data-driven healthcare solutions for women. Founded in 2015 and headquartered in New York, with an additional location in San Francisco, Tia offers a mobile application that features a range of services including birth control recommendations, sexual health advice, symptom tracking, and doctor locators. The platform empowers women to make informed decisions about their health by facilitating access to both in-office appointments and virtual care. Recognizing that traditional healthcare systems often overlook women's needs, Tia aims to create a distinctly female-centered model of care that addresses the unique healthcare challenges women face.

Soda Health

Seed Round in 2021
Founded in 2021, Soda Health is a Chicago-based healthcare technology company committed to reducing health disparities by addressing social determinants of health. It operates a platform that delivers personalized benefits, providing real-time access to essential services such as healthy food, over-the-counter medications, and transportation.

Intrinsic

Series A in 2021
Intrinsic Brands is an eCommerce acquisition and growth platform uniquely focused on digital-first health and wellness brands.

Cohere Health

Series B in 2021
Founded in 2019 and based in Boston, Cohere Health is a healthcare technology company dedicated to enhancing efficiency and effectiveness within the healthcare system. It achieves this by leveraging technology to simplify processes, improve communication among stakeholders, and ultimately optimize patient outcomes.

DexCare

Series A in 2021
DexCare is a Seattle-based company founded in 2021 that specializes in providing a platform-as-a-service solution for managing health system capacity and demand across various lines of care. The company's platform aims to transform traditional patient-to-provider relationships into scalable digital experiences, thereby increasing revenue from new patients while reducing acquisition costs. By optimizing access to healthcare services, DexCare helps healthcare institutions generate new patients, enhance satisfaction, achieve cost savings, and ensure that patients receive timely and effective care.

Unite Us

Series C in 2021
Unite Us is a veteran-led technology company founded in 2013 in New York, specializing in creating coordinated care networks that connect health and social service providers. The company develops a platform that enables providers to send and receive secure referrals, track individuals' health journeys, and report on outcomes across a variety of services. By integrating social determinants of health into patient care, Unite Us facilitates a cohesive and collaborative ecosystem that enhances the ability of communities to deliver services effectively. This innovative approach moves beyond traditional resource directories, allowing systems to measure impact and improve health outcomes on a larger scale.

Folx Health

Series A in 2021
Folx Health is a Boston-based telehealth platform founded in 2020, specializing in digital healthcare services tailored for the LGBTQIA+ community. It offers access to queer and trans clinicians, focusing on gender-affirming hormone therapy, sexual health, and family creation services.

Found

Series A in 2021
Found is dedicated to improving people’s overall wellbeing by making evidence-based weight loss accessible and affordable. The company was founded in 2019 and is headquartered in San Francisco, California, United States.

Story Health

Seed Round in 2020
Story Health Corporation is a healthcare technology company founded in 2020 and based in Saratoga, California. The company develops intelligent embedded virtualized clinical care software tools designed to assist healthcare specialists, including neurologists and primary care physicians, in understanding medical situations and making informed clinical decisions. Story Health's platform utilizes data from high-frequency sources to enhance therapy management through virtual protocols and adaptive machine learning. By focusing on patient-centered design, Story Health aims to bridge the gap between clinical evidence and real-world patient experiences, enabling clinicians to effectively address the physiological effects of disease and therapy.

Centivo

Series B in 2020
Centivo Corporation is a health insurance provider that specializes in offering innovative health plans for self-funded employers, employees, and clinicians. Established in 2016 and headquartered in Stamford, Connecticut, with additional offices in New York and Buffalo, Centivo serves as an alternative to traditional insurance carriers and third-party administrators. The company integrates technology, network management, claims processing, and customer support to effectively administer health benefits. Centivo emphasizes collaboration between employees and their primary care teams to coordinate healthcare needs, encouraging members to engage in high-value care through personalized matching tools and a user-friendly app. By focusing on controlling costs and improving navigation through the healthcare system, Centivo positions itself as a dedicated partner to employers, ensuring accountability and minimizing waste in healthcare spending.

MedArrive

Seed Round in 2020
MedArrive, Inc. is a New York-based company that operates a software-as-a-service health platform designed to enhance care management by connecting healthcare providers with patients in their homes. The platform integrates clinical data into electronic medical records and facilitates communication and billing processes. By utilizing emergency medical services professionals, MedArrive enables healthcare providers to deliver high-quality care at home, improving access for vulnerable populations while reducing overall healthcare costs. This innovative approach fosters patient self-advocacy and continuity of care, helping to re-engage patients in primary care and enhance health outcomes. MedArrive's technology and holistic care model represent a strategic effort to bridge the gap between virtual care and in-person support, ultimately benefiting both patients and healthcare providers.

Cohere Health

Series A in 2020
Founded in 2019 and based in Boston, Cohere Health is a healthcare technology company dedicated to enhancing efficiency and effectiveness within the healthcare system. It achieves this by leveraging technology to simplify processes, improve communication among stakeholders, and ultimately optimize patient outcomes.

Tia

Series A in 2020
Tia, Inc. is a health advisory platform focused on providing personalized and data-driven healthcare solutions for women. Founded in 2015 and headquartered in New York, with an additional location in San Francisco, Tia offers a mobile application that features a range of services including birth control recommendations, sexual health advice, symptom tracking, and doctor locators. The platform empowers women to make informed decisions about their health by facilitating access to both in-office appointments and virtual care. Recognizing that traditional healthcare systems often overlook women's needs, Tia aims to create a distinctly female-centered model of care that addresses the unique healthcare challenges women face.

Folx Health

Venture Round in 2020
Folx Health is a Boston-based telehealth platform founded in 2020, specializing in digital healthcare services tailored for the LGBTQIA+ community. It offers access to queer and trans clinicians, focusing on gender-affirming hormone therapy, sexual health, and family creation services.

Found

Seed Round in 2020
Found is dedicated to improving people’s overall wellbeing by making evidence-based weight loss accessible and affordable. The company was founded in 2019 and is headquartered in San Francisco, California, United States.

Verana Health

Series D in 2020
Verana Health, Inc. is a digital health company based in San Francisco, California, that specializes in transforming healthcare data into actionable insights. Founded in 2008 and formerly known as Digisight Technologies, the company connects healthcare providers with patients through innovative solutions. Its flagship product, SightBook, is a mobile application that enables users to test their vision and share results with their physicians in real-time, facilitating timely appointments and treatments. Verana Health manages data from over 20,000 healthcare providers and 70 electronic health record systems, leveraging its AI-enhanced platform, VeraQ™, to create a robust healthcare data ecosystem. By utilizing advanced analytics on curated datasets, Verana Health supports life sciences partners in improving clinical research and enhancing patient care outcomes.

Lightship

Series B in 2020
Founded in 2018, Lightship aims to enhance health equity globally by transforming clinical trials. It combines digital health innovations, technology, remote care, and high-quality clinical research to make studies more accessible and offer choices, keeping patients at the core of its work.

Unite Us

Series B in 2019
Unite Us is a veteran-led technology company founded in 2013 in New York, specializing in creating coordinated care networks that connect health and social service providers. The company develops a platform that enables providers to send and receive secure referrals, track individuals' health journeys, and report on outcomes across a variety of services. By integrating social determinants of health into patient care, Unite Us facilitates a cohesive and collaborative ecosystem that enhances the ability of communities to deliver services effectively. This innovative approach moves beyond traditional resource directories, allowing systems to measure impact and improve health outcomes on a larger scale.

Tia

Seed Round in 2019
Tia, Inc. is a health advisory platform focused on providing personalized and data-driven healthcare solutions for women. Founded in 2015 and headquartered in New York, with an additional location in San Francisco, Tia offers a mobile application that features a range of services including birth control recommendations, sexual health advice, symptom tracking, and doctor locators. The platform empowers women to make informed decisions about their health by facilitating access to both in-office appointments and virtual care. Recognizing that traditional healthcare systems often overlook women's needs, Tia aims to create a distinctly female-centered model of care that addresses the unique healthcare challenges women face.

Cohere Health

Founded in 2019 and based in Boston, Cohere Health is a healthcare technology company dedicated to enhancing efficiency and effectiveness within the healthcare system. It achieves this by leveraging technology to simplify processes, improve communication among stakeholders, and ultimately optimize patient outcomes.
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