Digitalis

Digitalis is a venture capital firm founded in 2016 and headquartered in New York, with additional offices in Boston, Los Angeles, and San Francisco. The firm focuses on investing in innovative solutions addressing complex challenges in both human and animal health. Digitalis collaborates with entrepreneurs, inventors, and scientists at various stages of development, aiming to support advancements across the entire healthcare ecosystem. Through its strategic investments, Digitalis seeks to drive progress in health-related technology and contribute to the improvement of health outcomes.

Stephen R. Allen

Partner

Amit Bansal

Partner

Cindy Cole

Technical Partner

Jonathan Friedlander Ph.D

Principal

Ben Jacobs

Partner

Auro Nair

Partner

Dac Nguyen

Technical Partner

Drew Taylor

Partner

Misti Ushio

Managing Partner

48 past transactions

Ascend supports manufacturing and process development projects from design through to clinical and commercial scales. They partner with biotechnology teams to embed scalable manufacturing in their operations from the beginning. They respond to customer inquiries by phone and contact form.

Terray Therapeutics

Series A in 2022
Terray Therapeutics, Inc. operates as a biotechnology company. The company develops treatments for intractable cause of human diseases. It engages in development of a screening platform for drug discovery and Platinum Technology, which is working on an electrode-like product for deep brain stimulation. The company was founded in 2018 and is based in Pasadena, California.

Faeth

Seed Round in 2022
Faeth Therapeutics is a healthcare company dedicated to enhancing cancer treatment through a deep understanding of the relationship between dietary nutrients and tumor growth. By aligning specific diets with tumor genotypes and treatment regimens, Faeth aims to limit the energy and resources that tumors need to proliferate, thereby improving patient outcomes in cancer therapy. Founded by leading researchers and clinicians, the company seeks to translate significant discoveries from cancer research laboratories into effective clinical practices, focusing on evidence-based approaches to optimize treatment strategies for cancer patients.

Good Therapeutics

Series B in 2021
Good Therapeutics develops new technology for self-regulating drugs that will provide a therapeutic activity when, where it is needed. It is an early-stage biotechnology company based in Seattle, Washington. They are developing context-dependent protein drugs that sense biomarkers and respond with therapeutic activity. Their goal is to make safer, more effective drugs that act only when and where they are needed, limiting systemic toxicity without reducing therapeutic efficacy. Their core technology is an algorithm for designing allosterically-regulated proteins. These proteins change their conformation (shape) when they bind a biomarker or metabolite, and in doing so activate a therapeutic domain. They are currently focused on immuno-oncology applications of the technology.

GRO Biosciences

Series A in 2021
GRO Biosciences is leveraging breakthrough technologies from computational protein design and synthetic biology to develop best-in-class protein therapeutics with enhanced properties. The company has established multiple genomically recoded strains of bacteria that can incorporate non-standard amino acids into proteins to confer increased potency, stability, and targeted delivery. GRO Biosciences is applying its technology platform to develop improved protein therapeutics for diabetes, growth disorders and autoimmunity. The company, co-founded by Dr. George Church, is located at the Harvard Life Lab, a shared laboratory space for high-potential life sciences and biotechnology startups founded by Harvard faculty, alumni, students, and postdoctoral scholars.

BIOMILQ

Series A in 2021
We leverage our patent-pending technology to produce nutritionally equivalent breastmilk from cultured human mammary cells. With Biomilq, families can achieve the recommended six months of exclusive breastfeeding while alleviating the climate impacts of bovine-based infant formula.

Scout Bio

Series B in 2021
Scout Bio, Inc. researches and develops one-time therapies for major chronic pet health conditions using veterinary biotechnology and gene therapy. It offers therapies for anemia associated with chronic kidney disease (CKD) in cats. The company offers pet therapeutics, including small molecular drugs, protein therapies, and gene therapies. Scout Bio, Inc. was founded in 2016 and is headquartered in Philadelphia, Pennsylvania.

Kingdom Supercultures

Series A in 2021
Kingdom Supercultures develops and produces microbial cultures that help food manufacturers to produce new varieties of food. The company produces and offers Koji, a Japanese food ingredient used to make miso, sake, soy sauce, and more. Its products helps in producing fermented sodas, beers, and plant-based dairy replacements. The company offers a platform that uses software and hardware automation to assemble microbial cultures for natural food production. The company was founded in 2019 and is based in Brooklyn, New York.

UnifiHealth

Seed Round in 2021
UnifiHealth is reimagining how health benefits are built and delivered to small businesses. The company was founded in 2019 and based in Columbus, Ohio.

PetMedix

Series B in 2021
PetMedix Ltd is a veterinary biopharmaceutical company based in Cambridge, United Kingdom, focused on developing innovative therapeutic drug solutions for pets. Founded in 2017, the company utilizes advanced scientific methods to create transgenic mouse platforms, specifically Ky9 and Felyne, which are designed to produce high-quality therapeutic antibodies tailored for pets. Drawing on over thirty years of expertise in human drug development, PetMedix aims to improve the health and well-being of animals by delivering effective therapies that enhance their quality of life.

Cayaba Care

Seed Round in 2021
Cayaba Care is a maternal health company offering community-based clinical services via technology-enabled multidisciplinary care teams.

Terray Therapeutics

Seed Round in 2021
Terray Therapeutics, Inc. operates as a biotechnology company. The company develops treatments for intractable cause of human diseases. It engages in development of a screening platform for drug discovery and Platinum Technology, which is working on an electrode-like product for deep brain stimulation. The company was founded in 2018 and is based in Pasadena, California.

AnimalBiome

Venture Round in 2021
AnimalBiome helps to restore gut health to the millions of dogs and cats in the US living with chronic digestive disorders by offering microbiome-based supplements and non-invasive diagnostics.

Aunt Bertha

Series D in 2021
Aunt Bertha is a Public Benefit Corporation that operates a social services search and referrals software platform designed to help individuals locate various welfare programs. Founded in 2010 and based in Austin, Texas, the company provides users with access to resources related to food, shelter, healthcare, employment, and financial assistance. The platform facilitates connections between those in need and available support services, streamlining the process of finding and applying for government and charitable programs. Aunt Bertha serves a diverse range of sectors, including healthcare, education, government, and child welfare, effectively reducing the administrative costs associated with social service program management by enabling online applications.

Code Ocean

Series A in 2021
Code Ocean, Inc. operates a cloud-based platform designed for computational reproducibility, enabling researchers and developers to share, discover, and execute code published in academic journals and conferences. Founded in 2015 and based in New York, the company offers an end-to-end workflow that supports reproducibility by providing tools for researchers to consolidate their code, data, and necessary dependencies into a single compute capsule. This platform facilitates collaboration from the inception of a project through to publication, allowing users to access and run published software without the need for local installations. Code Ocean enhances transparency by documenting the algorithms and processes used in research, catering to the needs of researchers, institutions, and publishers. Through its services, the company promotes the reuse of research results and the reproducibility of scientific findings.

Ansel Health

Series A in 2021
Brella is modernizing supplemental health benefits to build a world where health hardship doesn’t mean financial hardship. Brella’s simple supplemental plan covers 13,000+ conditions and pays cash on the diagnosis that you can use for anything that is needed on the road to recovery. Brella Insurance was founded in 2019 and is based in Hoboken, New Jersey.

SeQure DX

Venture Round in 2021
SeQure DX is in the business activities at non-commercial site business. It was founded in 2020 and is based in Waltham, Massachusetts.

UnifiHealth

Seed Round in 2021
UnifiHealth is reimagining how health benefits are built and delivered to small businesses. The company was founded in 2019 and based in Columbus, Ohio.

Onc AI

Venture Round in 2020
Onc AI, founded in 2020 and based in San Carlos, California, specializes in clinical oncology and offers a precision oncology clinical management platform. The company focuses on enhancing decision-making in cancer care through a comprehensive approach that encompasses genomics, proteomics, and radiomics. By leveraging deep learning technologies, Onc AI aims to provide actionable insights that empower healthcare providers in the effective treatment of cancer.

Nuperfect

Seed Round in 2020
Nuperfect is a company that specializes in designing and developing invisible orthodontic devices, specifically custom braces for teeth correction. Utilizing advanced technologies such as artificial intelligence, cloud computing, 3D reconstruction, and 3D printing, Nuperfect creates personalized correction solutions based on three-dimensional digital dental models. Additionally, the company offers offline dental scanning and home dental mold tools to facilitate data collection for its products. Customers can access Nuperfect's services and products through an online portal. Founded in 2019, Nuperfect is headquartered in Shenzhen, China.

Ansel Health

Seed Round in 2020
Brella is modernizing supplemental health benefits to build a world where health hardship doesn’t mean financial hardship. Brella’s simple supplemental plan covers 13,000+ conditions and pays cash on the diagnosis that you can use for anything that is needed on the road to recovery. Brella Insurance was founded in 2019 and is based in Hoboken, New Jersey.

Smalls

Series A in 2020
Smalls is a direct-to-consumer pet food company that produces human-grade and fresh food for cats. The company's cat food is prepared with human-grade ingredients and offers customized kits as per the cat's nutrition needs, enabling pet owners to get healthy and fresh food directly at their doorstep. It offers variants such as chicken and beef; freeze-dried chicken, and turkey and duck. In 2017, co-founders and best friends Matt Michaelson and Calvin headquartered the company in New York, New York.

Base5 Genomics

Venture Round in 2020
Base5 Genomics, Inc. is a biotechnology company that specializes in developing sequencing solutions aimed at personalized care. Founded in 2018 and headquartered in Palo Alto, California, the company provides technology that uncovers the complete genomic diversity in humans and various organisms. This capability allows healthcare professionals to tailor treatments to individual patients, enhancing the effectiveness of medical interventions. By focusing on the intricate details of genetic information, Base5 Genomics plays a crucial role in advancing personalized medicine.

Good Therapeutics

Series A in 2020
Good Therapeutics develops new technology for self-regulating drugs that will provide a therapeutic activity when, where it is needed. It is an early-stage biotechnology company based in Seattle, Washington. They are developing context-dependent protein drugs that sense biomarkers and respond with therapeutic activity. Their goal is to make safer, more effective drugs that act only when and where they are needed, limiting systemic toxicity without reducing therapeutic efficacy. Their core technology is an algorithm for designing allosterically-regulated proteins. These proteins change their conformation (shape) when they bind a biomarker or metabolite, and in doing so activate a therapeutic domain. They are currently focused on immuno-oncology applications of the technology.

Kenzen

Seed Round in 2019
Kenzen, Inc. specializes in developing personal health wearables, notably the Kenzen ECHO, a wireless smart patch designed for health and performance monitoring. This innovative patch offers personalized health insights and notifications that aid in improving performance, recovery, and injury prevention. The ECHO system includes components such as disposable patch sensors, a USB charging cable, and a mobile application that provides real-time data on users' performance and health. Kenzen's technology serves various sectors, including industrial environments, where it helps monitor vital signs to prevent heat-related injuries and over-exertion. The company, founded in 2014 by Sonia Sousa and Steve Pecko, operates from San Francisco, California, and distributes its products through various channels, including resellers and retail locations.

Scratch

Series B in 2019
Scratch Financial, operating under the brand Scratchpay, is the leading provider of accessible payment plans for veterinary care in the United States. Established in 2016 by Caleb Morse and John Keatley, the company is based in Los Angeles, California. Scratchpay collaborates with veterinary clinics to offer pet owners straightforward and pet-friendly financing options. The platform allows users to apply for and receive approval for payment plans in approximately 90 seconds, facilitating timely access to essential veterinary services. Scratchpay aims to enhance the affordability and transparency of veterinary care, ultimately ensuring that more pet owners can obtain the medical attention their animals require.

The Mighty

Series B in 2019
The Mighty is a digital health community designed to empower and connect individuals facing health challenges and disabilities. It provides a platform for users to share their personal experiences through stories and videos related to disability, disease, and mental illness. By fostering connections among users with similar experiences, The Mighty aims to create a supportive environment that encourages positivity and resilience in the face of adversity.

Aunt Bertha

Series C in 2019
Aunt Bertha is a Public Benefit Corporation that operates a social services search and referrals software platform designed to help individuals locate various welfare programs. Founded in 2010 and based in Austin, Texas, the company provides users with access to resources related to food, shelter, healthcare, employment, and financial assistance. The platform facilitates connections between those in need and available support services, streamlining the process of finding and applying for government and charitable programs. Aunt Bertha serves a diverse range of sectors, including healthcare, education, government, and child welfare, effectively reducing the administrative costs associated with social service program management by enabling online applications.

Code Ocean

Series A in 2019
Code Ocean, Inc. operates a cloud-based platform designed for computational reproducibility, enabling researchers and developers to share, discover, and execute code published in academic journals and conferences. Founded in 2015 and based in New York, the company offers an end-to-end workflow that supports reproducibility by providing tools for researchers to consolidate their code, data, and necessary dependencies into a single compute capsule. This platform facilitates collaboration from the inception of a project through to publication, allowing users to access and run published software without the need for local installations. Code Ocean enhances transparency by documenting the algorithms and processes used in research, catering to the needs of researchers, institutions, and publishers. Through its services, the company promotes the reuse of research results and the reproducibility of scientific findings.

Pawp

Seed Round in 2019
Pawp, Inc. is a New York-based company founded in 2018 that offers an online platform for pet owners to manage their pets' needs efficiently. The service provides users with unlimited 24/7 access to licensed veterinarians and features a $3,000 annual emergency fund for pet healthcare expenses. This model serves as an alternative to traditional pet insurance, covering emergencies of any size and aiming to make pet care more affordable. Through curated product recommendations and expert advice, Pawp seeks to enhance the overall pet ownership experience while addressing the financial challenges associated with pet care.

Scout Bio

Series B in 2019
Scout Bio, Inc. researches and develops one-time therapies for major chronic pet health conditions using veterinary biotechnology and gene therapy. It offers therapies for anemia associated with chronic kidney disease (CKD) in cats. The company offers pet therapeutics, including small molecular drugs, protein therapies, and gene therapies. Scout Bio, Inc. was founded in 2016 and is headquartered in Philadelphia, Pennsylvania.

Terray Therapeutics

Seed Round in 2019
Terray Therapeutics, Inc. operates as a biotechnology company. The company develops treatments for intractable cause of human diseases. It engages in development of a screening platform for drug discovery and Platinum Technology, which is working on an electrode-like product for deep brain stimulation. The company was founded in 2018 and is based in Pasadena, California.

GRO Biosciences

Seed Round in 2019
GRO Biosciences is leveraging breakthrough technologies from computational protein design and synthetic biology to develop best-in-class protein therapeutics with enhanced properties. The company has established multiple genomically recoded strains of bacteria that can incorporate non-standard amino acids into proteins to confer increased potency, stability, and targeted delivery. GRO Biosciences is applying its technology platform to develop improved protein therapeutics for diabetes, growth disorders and autoimmunity. The company, co-founded by Dr. George Church, is located at the Harvard Life Lab, a shared laboratory space for high-potential life sciences and biotechnology startups founded by Harvard faculty, alumni, students, and postdoctoral scholars.

PetMedix

Series A in 2019
PetMedix Ltd is a veterinary biopharmaceutical company based in Cambridge, United Kingdom, focused on developing innovative therapeutic drug solutions for pets. Founded in 2017, the company utilizes advanced scientific methods to create transgenic mouse platforms, specifically Ky9 and Felyne, which are designed to produce high-quality therapeutic antibodies tailored for pets. Drawing on over thirty years of expertise in human drug development, PetMedix aims to improve the health and well-being of animals by delivering effective therapies that enhance their quality of life.

CareDox

Series C in 2019
CareDox Inc. operates a care coordination platform designed to assist parents and schools in managing and sharing medical information effectively. Founded in 2010 and based in New York, the company focuses on streamlining the collection and accessibility of health data to enhance child safety. Its platform enables parents to organize their family's health information, eliminating the need for paper forms during school, camp, and daycare enrollment. Parents can selectively share health information while maintaining a secure record of their children's medical history. For schools, CareDox facilitates the medical enrollment process, ensuring compliance with safety requirements and providing school staff, including nurses and teachers, with essential health information about students. This access allows for real-time insights into allergies, medications, and special dietary needs, ultimately improving health outcomes and supporting the continuity of care for children in the K-12 education system.

Good Therapeutics

Series A in 2019
Good Therapeutics develops new technology for self-regulating drugs that will provide a therapeutic activity when, where it is needed. It is an early-stage biotechnology company based in Seattle, Washington. They are developing context-dependent protein drugs that sense biomarkers and respond with therapeutic activity. Their goal is to make safer, more effective drugs that act only when and where they are needed, limiting systemic toxicity without reducing therapeutic efficacy. Their core technology is an algorithm for designing allosterically-regulated proteins. These proteins change their conformation (shape) when they bind a biomarker or metabolite, and in doing so activate a therapeutic domain. They are currently focused on immuno-oncology applications of the technology.

MollyBox

Series B in 2018
MollyBox is a subscription-based e-commerce platform for pet-owners. The company offers a monthly themed box of pet foods and supplies. MollyBox was founded in 2015 by Yifu Sun and Yi Ju and is based in Shanghai, China.

Girihlet

Seed Round in 2018
Girihlet Inc. is a genetic-sequencing company based in Oakland, California, that specializes in providing rapid and accurate deep sequencing services. Established in 2012, the company focuses on non-canonical genomics solutions, particularly in the profiling of T cell receptor repertoires. Through the development of novel, bias-free sequencing technologies, Girihlet aims to leverage mitochondrial DNA and T cell receptors as biomarkers for diagnostic and therapeutic applications across various medical disorders. By enhancing the understanding of the immune system, Girihlet contributes to advancements in precision medicine and the identification of potential treatments.

Rejuvenate Bio

Seed Round in 2018
Rejuvenate Bio Inc is a biotechnology company based in Brookline, Massachusetts, founded in 2017. The company specializes in developing gene therapies aimed at enhancing the health and longevity of domesticated animals, particularly dogs. Rejuvenate Bio offers anti-aging treatments by introducing new DNA instructions into the animals' bodies. Additionally, the company provides gene therapies designed to target and cure specific diseases in pets, contributing to improved overall well-being and lifespan.

Scratch

Series A in 2018
Scratch Financial, operating under the brand Scratchpay, is the leading provider of accessible payment plans for veterinary care in the United States. Established in 2016 by Caleb Morse and John Keatley, the company is based in Los Angeles, California. Scratchpay collaborates with veterinary clinics to offer pet owners straightforward and pet-friendly financing options. The platform allows users to apply for and receive approval for payment plans in approximately 90 seconds, facilitating timely access to essential veterinary services. Scratchpay aims to enhance the affordability and transparency of veterinary care, ultimately ensuring that more pet owners can obtain the medical attention their animals require.

Kenzen

Convertible Note in 2018
Kenzen, Inc. specializes in developing personal health wearables, notably the Kenzen ECHO, a wireless smart patch designed for health and performance monitoring. This innovative patch offers personalized health insights and notifications that aid in improving performance, recovery, and injury prevention. The ECHO system includes components such as disposable patch sensors, a USB charging cable, and a mobile application that provides real-time data on users' performance and health. Kenzen's technology serves various sectors, including industrial environments, where it helps monitor vital signs to prevent heat-related injuries and over-exertion. The company, founded in 2014 by Sonia Sousa and Steve Pecko, operates from San Francisco, California, and distributes its products through various channels, including resellers and retail locations.

Elemental Machines

Series A in 2018
Elemental Machines is revolutionizing science-based industries with a smart lab platform that offers powerful, data-driven insights to improve laboratory operations, research, development, and manufacturing outcomes. Continuously monitoring equipment and environmental variables provides new levels of clarity, transparency and consistency, and improved repeatability and gathers new data sets for advanced analytics.

GRO Biosciences

Seed Round in 2018
GRO Biosciences is leveraging breakthrough technologies from computational protein design and synthetic biology to develop best-in-class protein therapeutics with enhanced properties. The company has established multiple genomically recoded strains of bacteria that can incorporate non-standard amino acids into proteins to confer increased potency, stability, and targeted delivery. GRO Biosciences is applying its technology platform to develop improved protein therapeutics for diabetes, growth disorders and autoimmunity. The company, co-founded by Dr. George Church, is located at the Harvard Life Lab, a shared laboratory space for high-potential life sciences and biotechnology startups founded by Harvard faculty, alumni, students, and postdoctoral scholars.

Kenzen

Seed Round in 2017
Kenzen, Inc. specializes in developing personal health wearables, notably the Kenzen ECHO, a wireless smart patch designed for health and performance monitoring. This innovative patch offers personalized health insights and notifications that aid in improving performance, recovery, and injury prevention. The ECHO system includes components such as disposable patch sensors, a USB charging cable, and a mobile application that provides real-time data on users' performance and health. Kenzen's technology serves various sectors, including industrial environments, where it helps monitor vital signs to prevent heat-related injuries and over-exertion. The company, founded in 2014 by Sonia Sousa and Steve Pecko, operates from San Francisco, California, and distributes its products through various channels, including resellers and retail locations.

Somatix

Series A in 2017
Somatix, Inc. specializes in developing wearable remote patient monitoring (RPM) solutions that utilize advanced gesture detection technology and machine learning. Founded in 2015 and headquartered in New York, the company has created platforms that analyze large volumes of gesture data in real time, allowing for the passive detection of various physical and emotional indicators. These indicators help identify risk factors such as poor medical compliance, inactivity, falls, and dehydration. Notable products include SafeBeing, aimed at elderly individuals, and SmokeBeat, which assists in smoking cessation. Somatix’s solutions cater to a diverse clientele, including corporate employers, health insurance companies, and clinics, facilitating improved health interventions and ongoing support for patients through insights derived from commonly used wearable devices like smartwatches and smartbands.

CareDox

Series B in 2016
CareDox Inc. operates a care coordination platform designed to assist parents and schools in managing and sharing medical information effectively. Founded in 2010 and based in New York, the company focuses on streamlining the collection and accessibility of health data to enhance child safety. Its platform enables parents to organize their family's health information, eliminating the need for paper forms during school, camp, and daycare enrollment. Parents can selectively share health information while maintaining a secure record of their children's medical history. For schools, CareDox facilitates the medical enrollment process, ensuring compliance with safety requirements and providing school staff, including nurses and teachers, with essential health information about students. This access allows for real-time insights into allergies, medications, and special dietary needs, ultimately improving health outcomes and supporting the continuity of care for children in the K-12 education system.

Second Genome

Series B in 2016
Second Genome’s mission is to transform lives with medicines developed through innovative microbiome science. Second Genome has built a novel platform for microbiome drug discovery. Second Genome has completed more than 400 microbiome studies, analyzing more than 75,000 samples, for internal R&D, as well as for external partners across government, academia, pharmaceutical, nutrition and industrial companies. The team leverages its microbiome analysis platform with its partners’ specific expertise to generate insightful findings that can accelerate research programs by elucidating the role of the microbiome in human health conditions, agriculture, animal health and other industries. The company has established a pipeline of therapeutic products for the treatment of inflammation and metabolic diseases.
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