Ann Arbor SPARK

Asalyxa Bio is a drug development and platform technology company focused on novel therapeutics to treat major unmet medical needs caused by the dysregulation of immune signaling. With applications across a wide array of disease areas and conditions, Asalyxa Bio's platform technology enables delivery of existing and novel drugs directly into over-reactive immune cells.

Orbion Space Technology, Inc. specializes in the development and manufacturing of plasma propulsion systems designed for small satellites. Founded in 2016 and headquartered in Houghton, Michigan, the company provides electric propulsion technology that enables the last-mile delivery of spacecraft from launch vehicles to their designated orbits. This technology assists clients in maneuvering satellites in space, avoiding potential collisions, and ensuring safe de-orbiting at the conclusion of their mission lifetimes. Through its innovative propulsion systems, Orbion enhances the operational capabilities and longevity of small satellite missions.

Barracuda Labs is a research and threat analysis team within Barracuda Networks, focused on enhancing cybersecurity through innovative technologies and actionable threat intelligence. The team evaluates the threat landscape across various domains, including email, web, network, and cloud security, aiming to improve security awareness and education. By collaborating with government and law enforcement agencies, Barracuda Labs contributes to the reduction of cybersecurity crimes. The team comprises security engineers and research scientists who utilize diverse data sources, including partnerships and real-time scans, to inform their findings. Barracuda Networks, established in 2002 and headquartered in Campbell, California, designs and sells a range of security solutions, such as email and web security appliances, data protection services, and application delivery solutions. Its products cater to various industries, including education, healthcare, and finance, and are distributed through a network of partners both domestically and internationally.

SPLT is an enterprise-first carpooling and car sharing platform that connects employees within organizations to share their commute, saving time and money while reducing traffic congestion and lowering CO2 emissions.

Banza is a food manufacturer that focuses on producing pasta products. Its first products feature a pasta made from chickpeas. The company is driven by a mission to make nutritious food more accessible. Its products are now available in 8,000 stores, including Target, Kroger, and Whole Foods. Banza has been endorsed in the NYT, Food & Wine, Bon Appetit, on Good Morning America, Today, and been named one of TIME Magainze's 25 Best Inventions of the Year. Banza was founded in 2014 and is headquartered in Detroit, Michigan.

TurtleCell will offer its customers unique and stylish protective cases for the most popular smart phones on the market. The first case to be offered will include a mechanism to retract and store a set of headphones inside the volume of the protective case. TurtleCell’s proprietary design allows a full length cord to be stored within a volume thinner than the leading external battery case.

Argo Labs' team has designed and developed on the web for small businesses with one employee and large corporations with thousands, learning a lot of do’s and dont’s along the way. The company builds sites from the ground up, shot videos for local businesses and families and designed entire online brands. Not to mention we have a perfect track record of meeting each of them one on one to make whatever they need 100% unique. The company combines backgrounds in computer science, engineering, videography, graphic design, marketing, and entrepreneurship. Everyone at Argo Labs has owned or worked for small businesses and has done freelance work on their own.

SkySpecs, Inc. specializes in developing unmanned aerial vehicles designed to automate operations and maintenance for the wind energy sector. Based in Ann Arbor, Michigan, with an additional office in Amsterdam, the company offers a range of services including analytics, wind turbine blade maintenance, and engineering projects. Its solutions feature Horizon, a software tool that facilitates collaboration and data management for blade operations and maintenance, enabling streamlined communication and efficient repair project execution. Founded in 2012, SkySpecs employs custom autonomous drones to perform inspections, diagnostics, and maintenance of utility-scale wind turbines, providing high-quality data and enhancing safety during inspections. The company aims to improve productivity and efficiency in the renewable energy industry through its innovative technologies and services.

CureLauncher, LLC is a healthcare company based in Bloomfield Hills, Michigan, that specializes in clinical trial matching services. Established in 2012, the company connects patients with new treatment options tailored to their specific health conditions and personal goals. In addition to assisting patients, CureLauncher also supports caregivers and healthcare professionals in navigating available clinical trials. Through its online platform, CureLauncher aims to simplify the process of finding suitable medical treatments, ultimately helping users maintain their health and well-being.

TM3 Systems develops smart, mobile microgrid products for remote and off-grid power applications.

TM3 Systems develops smart, mobile microgrid products for remote and off-grid power applications.

Seelio is a student portfolio network designed for college students and educators. They build custom portfolio networks and galleries for engineering, design, and business programs to empower students to document their learnings and showcase their work. Schools on Seelio include [Massachusetts Institute of Technology](http://seelio.com/gallery/q/MIT), [University of Michigan](http://seelio.com/g/UMDesignExpoW13), and [University of Texas - Austin](http://seelio.com/gallery/t/utdmi2013). Founded in 2011, Seelio is a venture-backed startup in Ann Arbor, MI, and has been featured in Forbes, TechCrunch, and MTV.

IROA Technologies LLC offers isotopes of carbon used in identifying and analyzing chemical signatures in biological compounds. The company was incorporated in 2013 and is based in Ann Arbor, Michigan.

AutoBike, Inc. is a manufacturer of bicycles based in Troy, Michigan, founded in 2011. The company has developed a unique automatic shifting technology aimed at enhancing the cycling experience by making it simpler, more comfortable, and enjoyable. This technology is integrated into AutoBike's own line of bicycles and is also offered to other original equipment manufacturers (OEMs) for inclusion in their products.

Eloquence Communications is a healthcare IT company focused on enhancing care delivery through innovative communication solutions. The company develops nurse-call systems utilizing its proprietary communication technology, Eloquence, which facilitates bi-directional remote communication between patients and their care providers. Eloquence Communications offers two main products: the Advanced Communication System (ACS) and the Language Access Solution (LAS), both designed to enable quick and accurate exchanges between patients and the most qualified providers. By addressing language barriers and improving communication in healthcare settings, Eloquence Communications aims to optimize staffing allocation, enhance workflow efficiency, and ultimately improve patient care outcomes.

Quikly is a digital marketing platform that empowers marketers to consistently acquire, activate, and retain customers, which leads to superior ROI. Leveraging elements of consumer psychology, their solutions deliver highly effective and measurable results across nearly every marketing initiative. Quikly’s technology provides an immediate way for brands to boost digital activation and engagement within existing channels like email, social, and mobile to deliver meaningful revenue over a short period of time. Quikly was founded in 2012 and is headquartered in Detroit, Michigan.

AlertWatch, Inc. is an Ann Arbor-based spinoff from the University of Michigan Health System, and produces clinical decision support systems for hospitals. Founded in 2011, AlertWatch simplifies patient monitoring with intuitive products for the OR or ICU. AlertWatch products now run at the University of Michigan and several other training hospitals across the United States. Contact us if you’re interested in starting a pilot project at your site.

Beet, Inc. specializes in providing diagnostic and analytical tools designed to enhance problem-solving capabilities for operations facing complex assembly and automation challenges. Founded in 2011 and headquartered in Plymouth, Michigan, with an additional office in China, the company offers a range of software solutions under its ENVISION brand. This includes ENVISION Enterprise SMART, ENVISION Sentinel SMART, and ENVISION System Scope, which cater to various operational scales and needs. Additionally, Beet provides a cloud-based Software-as-a-Service solution and consulting services. Its Process Visibility System (PVS) transforms manufacturing workflows by promoting proactive management and predictive maintenance, ultimately maximizing existing asset capacity and reducing unplanned downtime. The company's technology plays a crucial role in advancing manufacturers' efforts towards Industrial IoT and Industry 4.0, positioning them to improve production efficiency through real-time data utilization. Beet serves a diverse clientele, including automotive original equipment manufacturers and tooling manufacturers.

Beet, Inc. specializes in providing diagnostic and analytical tools designed to enhance problem-solving capabilities for operations facing complex assembly and automation challenges. Founded in 2011 and headquartered in Plymouth, Michigan, with an additional office in China, the company offers a range of software solutions under its ENVISION brand. This includes ENVISION Enterprise SMART, ENVISION Sentinel SMART, and ENVISION System Scope, which cater to various operational scales and needs. Additionally, Beet provides a cloud-based Software-as-a-Service solution and consulting services. Its Process Visibility System (PVS) transforms manufacturing workflows by promoting proactive management and predictive maintenance, ultimately maximizing existing asset capacity and reducing unplanned downtime. The company's technology plays a crucial role in advancing manufacturers' efforts towards Industrial IoT and Industry 4.0, positioning them to improve production efficiency through real-time data utilization. Beet serves a diverse clientele, including automotive original equipment manufacturers and tooling manufacturers.

Advanced Battery Concepts, LLC is a battery technology development company based in Clare, Michigan, founded in 2008. The company specializes in designing and developing bi-polar lead-acid batteries, which are aimed at enhancing performance across various sectors, including military, industrial, stationary, renewable, automotive, and motive markets. Advanced Battery Concepts focuses on addressing challenges associated with bipolar batteries by offering products that ensure uniform current density, increased active material utilization, and improved energy and power density. These innovations allow clients to achieve better battery performance while reducing production costs compared to traditional lead-acid batteries. The company was previously known as Advanced Battery Concepts Michigan, changing its name in March 2011.

3D Biomatrix Inc. designs and manufactures three-dimensional cell culture plates and scaffolds for cellular assays in drug discovery. Its scaffolds are used by researchers and drug discovery experts in bone-marrow, hepatocytes, and thymus applications. 3D Biomatrix Inc. was founded in 2010 and is based in Ann Arbor, Michigan.

Fusion Coolant Systems, Inc. specializes in manufacturing and marketing advanced coolant and lubrication systems for the manufacturing industry, utilizing supercritical carbon dioxide technology. The company offers products such as Pure-Cut 1000 and LUBE-CUT 1600, which deliver supercritical CO2 with varying lubrication rates for different cutting applications. These systems enhance production rates and extend tool life while addressing the shortcomings of traditional metalworking fluids, which can pose health and environmental risks. Fusion Coolant's innovative CHiP Lube system significantly outperforms conventional methods, reducing costs and eliminating toxic waste. The company's products find applications in various sectors, including medical implants, aerospace, automotive, and power generation. Fusion Coolant Systems, founded in 2009 and based in Canton, Michigan, also maintains an office in Saint-Priest, France, and has a strategic partnership with Air Liquide.

Larky, Inc. is a marketing and engagement platform that enables organizations to connect with their audiences through targeted geo-notifications and relevant communications. The company offers a mobile platform called Nudge, which facilitates timely interactions, and Larky Classic, a mobile engagement solution that enhances member relationships and supports local businesses. Larky also provides a merchant-funded loyalty platform that offers instant savings at local merchants, enhancing brand visibility. The company serves a diverse clientele that includes financial institutions, health insurance providers, universities, and media companies across the United States and Canada. Founded in 2011 and based in Ann Arbor, Michigan, Larky was previously known as PerkPerk, Inc.

Algal Scientific has two distinct business units that serve the animal feed, human nutrition, and wastewater treatment industries. One unit is focused on the production of their ProGlucan beta-glucan products for animal feeds and human nutrition. The second unit is dedicated to the commercialization of their Hypertrophic wastewater treatment system, which they license to customers in the food and beverage industry. It was acquired by Kemin Industries in March 2017. It was founded in 2017 and is based in Plymouth, Michigan.

New Eagle specializes in the development of mechatronic control systems aimed at addressing challenges in mechanical systems. The company designs electronic control modules for a diverse range of applications, including electric and hybrid vehicles, autonomous vehicles, intelligent machines, hydraulic systems, and engine systems. New Eagle offers end-to-end solutions, creating custom applications tailored to client needs. Their expertise in selecting appropriate hardware and developing control systems ensures that these solutions are both scalable and reliable, utilizing efficient embedded model-based development techniques.

Local Orbit is a developer of business management tools designed to address the challenges within the food distribution system. Through extensive engagement with farmers, food producers, chefs, and consumers, the company has identified issues related to disconnected markets and inefficient communication. Local Orbit's platform facilitates multi-channel sales, streamlined purchasing, and effective business management, serving various stakeholders in the food supply chain. By providing back-office software for entrepreneurs, farmers, food hubs, and independent distributors, the company enables clients to connect wholesale buyers with local producers, thereby supporting the development of emerging supply chains in the connected food economy.

Envy Modular Wall Systems specializes in the manufacturing and installation of lightweight modular panels designed for temporary construction barriers. Founded by Doug Spear, the company emerged from extensive experience in construction and business, addressing the need for a versatile wall system that meets the demands of various industries. The panels are easy to assemble and disassemble, utilizing 100% recycled materials, which makes them reusable after dismantling and fully recyclable thereafter. This innovative approach allows service companies in sectors such as industrial construction, airports, casinos, malls, and stadiums to expedite project timelines while maintaining environmental sustainability.

Mitostem, Inc. was founded in 2008 with the goal to drive innovation, and accelerate the scientific breakthroughs that will advance Stem Cell research and the field of Regenerative Medicine. MitoStem focuses on developing and commercializing novel technologies to advance stem cell research and the field of regenerative medicine. Stem cells have the ability to reproduce themselves (self-renew) or differentiate into each of the cell types found in the body. In the future, Pluripotent Stem Cells (PSC) will be able to replace diseased and damaged organs. Until recently, only stem cells derived from embryos were pluripotent. However, controversies are associated with using cells from embryos, and they can only be used for study of diseases that are diagnosed during assisted reproduction procedures (in vitro fertilization).

Atterocor, Inc. focuses on research and development of therapeutics for adrenal disease. Atterocor, Inc. was incorporated in 2012 and is based in Ann Arbor, Michigan.

FreeStride Therapeutics, Inc. was created for one purpose: to develop a companion animal therapy that goes beyond medicating the pain of arthritis and lameness by targeting the mechanisms that result in healing. They are dedicated to creating a safe, effective treatment that will restore horses, dogs and cats to active lifestyles so they can enjoy their lives with you. Their management team draws upon decades of experience in biotechnology, research, the business of Life Science, and drug development.

Seelio is a student portfolio network designed for college students and educators. They build custom portfolio networks and galleries for engineering, design, and business programs to empower students to document their learnings and showcase their work. Schools on Seelio include [Massachusetts Institute of Technology](http://seelio.com/gallery/q/MIT), [University of Michigan](http://seelio.com/g/UMDesignExpoW13), and [University of Texas - Austin](http://seelio.com/gallery/t/utdmi2013). Founded in 2011, Seelio is a venture-backed startup in Ann Arbor, MI, and has been featured in Forbes, TechCrunch, and MTV.

Axonia Medical is a privately owned-company located in Kalamazoo MI, founded by the University of Pennsylvania, Dr. Douglas H. Smith, The Robert A. Groff Endowed Professor and Vice Chairman for Research, Department of Neurosurgery, University of Pennsylvania, and Dr. Harry C. Ledebur, Fmr. Executive in Residence at Southwest Michigan Life Science Venture Fund. Axonia Medical is pioneering a revolutionary and proprietary approach to repair and restore damaged peripheral or central nervous systems using tissue-engineered nerve grafts (TENGs). By recapitulating the anatomy of the nervous system, TENGs are expected to bridge lost nervous tissue and jump-start regenerative mechanisms to achieve levels of functional recovery not possible with current technologies. As a result, TENGs may not only change the way nervous system injuries are treated, but also clinical expectations for restoration or recovery of sensory, motor and/or cognitive deficits

Celsee Diagnostics (formerly DeNovo Sciences) mission is to provide an easy to use platform for cancer research and diagnosis. Specifically, the company will sell an instrument system and reagent kit that allows for the separation, detection, and retrieval of circulating tumor cells (CTCs) from peripheral whole blood as an alternative to traditionally painful and invasive biopsies. Their company is developing a proprietary product that will not only allow researchers to identify and capture rare and difficult to harvest cancer cells in a microfluidic chip but also enable them to conduct downstream molecular analysis. This technology allows for the development of personalized therapies as well as the ability to monitor patient prognosis.

Oxus is a technology company that designs and manufactures oxygen concentrator products for several markets. Oxus has been in business for over 13 years. Oxus is proud to manufacture the Oxus Portable Oxygen Concentrator in the USA.

Blaze develops technologies that enable integrated and standardized assessments of blood damage, particularly for red blood cells (RBC). The company’s principal product lines include RBC Mechanical Fragilimeter™ systems for testing the mechanical fragility (MF) of red blood cells, and RBC Hemolysis Tester systems which also include the Fragilimeter™ capability. Initial models of these systems are for a wide range of industrial R&D and other research applications, while subsequent lines will target medical applications.

First Sense Medical provides an automated tester for breast cancer screening. It offers Breast Exam, a device that uses advanced thermal profiling for automated testing. The company’s Breast Exam system allows input of biopsy data, compares data nationally, updates the algorithms, and provides for updates to the tester for continual improvement.

Ventech, LLC provides mobile heating solutions. It offers Liquid Heat Generator, a rapid auxiliary heating system for vehicle applications. The company also provides vehicle harnesses, control modules, mounting brackets, dashboard switches, belts, drive pulleys, idlers, hoses, and fasteners and other parts. It offers its products for school buses, mass transits, and bus OEMs. The company provides its products through dealers in the United States and Canada. Ventech, LLC was founded in 2003 and is based in Wixom, Michigan.

FlockTAG operates a universal loyalty card network aimed at supporting independent neighborhood businesses by enhancing customer loyalty programs. The company has developed a mobile loyalty system that simplifies the process for businesses to manage their customer engagement initiatives. By partnering with local merchants, FlockTAG enables them to offer meaningful rewards and discounts to customers, fostering a stronger connection between businesses and their clientele. Customers can easily register for a FlockTAG card at participating locations, allowing them to earn points and access exclusive deals at various venues. This initiative not only benefits consumers by providing attractive offers but also helps businesses boost profitability by reducing competitive pricing pressures.

Empirical Bioscience, LLC is a company based in Grand Rapids, Michigan, that specializes in designing and manufacturing high-grade molecular biology reagents for various applications in research, education, and diagnostics. The company offers a wide range of PCR reagents optimized for standard, quantitative, and real-time PCR research across human, animal, and plant DNA. Their product lineup includes the rEVAlution qPCR Master Mix, an environmentally friendly hot-start qPCR mixture, and the Taq 2x MeanGreen Master Mix, which provides a ready-to-use solution for efficient PCR amplification. Additionally, Empirical Bioscience supports custom configurations of its products and offers technical assistance for assay and product development. The company, incorporated in 2009, was previously known as Syzygy Biotech Inc. and rebranded in February 2014.

VNN, Inc. operates a high school sports marketing and networking platform that enables athletes to share videos, pictures, stories, and scores while allowing coaches to report game results to media outlets. Founded in 2010 and based in Grand Rapids, Michigan, the company serves schools across numerous states, including Alabama, California, and Texas. VNN is recognized as the largest and fastest-growing platform of its kind in the United States, catering to a community of over 7 million fans and adding approximately 8,000 fans daily. The platform aggregates the fragmented high school sports market, enhancing the consumer experience by providing digital and Internet advertising and promotional services.

ePaySelect restructures monthly payments into smaller, more affordable payments that are much less than the customer expects. These automated payments are collected on paydays, held and paid to the lender on the due date. This eliminates late fees and protects credit ratings. Retailers benefit because smaller payments are inherently easier to sell. Customers include retailers like auto dealerships or anyone who needs help making monthly payments

Coliant Corporation specializes in the manufacturing and distribution of rugged electrical devices and accessories designed for powersport environments. The company offers a wide range of products, including powersport connectors, tire inflaters, battery charging solutions, and heated clothing such as jacket liners and gloves. Additionally, Coliant provides various mounting systems, power distribution products, and direct power cables compatible with devices like iPods and GPS units. Their products are designed for use with motorcycles, snowmobiles, all-terrain vehicles, and personal watercraft, and are available through dealers and online in multiple regions, including the United States, Europe, and Asia. Founded in 2001 and based in Warren, Michigan, Coliant serves both individual customers and powersport vehicle manufacturers, positioning itself as a reliable provider in the industry.

Clean Emission Fluids, Inc. manufactures fueling and fluid dispensing solutions for the transportation industry. It also resells biofuels, clean diesel, and emission related fluids. The company’s product enables fleet operators, truck stops, gas stations, and municipal fleets to store and dispense fluids and fuels. Clean Emission Fluids, Inc. was incorporated in 2007 and is based in Grosse Pointe, Michigan.

Ix Innovations is dedicated to enhancing the usability of electrical test and measurement instrumentation.

Estrakon is a fabrication company that specializes in designing and producing electronic signage and custom marketing media using a variety of materials. With advanced facilities in the USA, UK, and China, Estrakon focuses on creating visually appealing products that enhance brand visibility. The company is recognized for its innovative edge-lit display technologies, which are particularly effective in premium brand advertising and consumer displays. Committed to quality, Estrakon employs the latest construction techniques to ensure products are both durable and cost-effective for large-scale production. They prioritize research and development to continuously improve their offerings and maintain a competitive edge. Clear communication between clients and Estrakon's design and production teams is emphasized throughout the project lifecycle to ensure that all specifications are met precisely.

Arbor Plastic Technologies, LLC is a manufacturer and marketer of specialty additives and related delivery systems for the plastic resin industry. Established in 2007 and based in Sterling Heights, Michigan, the company produces a range of products including process enhancer additives, multi-functional pellets, and foaming agents. Its innovative additive delivery system allows for the integration of various additives—such as UV stabilizers, fire retardants, and colorants—into a single pellet, which enhances production efficiency and provides significant value to clients in the additive and plastic industries.

LEID Products, also known as Law Enforcement Intelligent Devices, LLC, specializes in the manufacturing of electronic lockers and cabinets designed to enhance asset security for various organizations, particularly police departments. Their innovative systems utilize electronic tracking and fingerprinting technology to safeguard critical assets such as firearms, radios, and other equipment. Beyond law enforcement, LEID's products have been employed in diverse sectors, including amusement parks for tracking radios, libraries for managing books and media, and businesses for securing sensitive documents. These solutions offer biometric, keypad, and card swipe access, ensuring that valuable assets are both protected and easily monitored.

RetroSense Therapeutics is a biotechnology company developing life-enhancing gene therapies designed to restore vision in patients suffering from blindness due to retinitis pigmentosa (RP) and advanced dry age-related macular degeneration (advanced dry-AMD). There are currently no FDA approved drugs to improve or restore vision in patients with these retinal degenerative conditions. The company's approach to using optogenetics in vision restoration is based on pioneering, proprietary research conducted at Wayne State University and Massachusetts General Hospital. Founded in 2009, RetroSense Therapeutics is headquartered in Ann Arbor, Michigan.

Practical EHR Solutions, Pehr for short (pronounced “pear”), is a company that specializes in implementing and supporting electronic health records in physician groups. Pehr's mission is to improve patient outcomes. As healthcare professionals, the Pehr founders understand just how important a physician’s individuality is and have developed a unique and practical electronic health record implementation methodology to preserve that individuality. Pehr focuses on enhancing the physician experience by improving the physician’s work day, increasing the practice’s profitability and improving quality and safety. This results in quick acceptance and full functionality use of the EHR. It is this use of full feature functionality that patient outcomes can, and will, improve.

Empirical Bioscience, LLC is a company based in Grand Rapids, Michigan, that specializes in designing and manufacturing high-grade molecular biology reagents for various applications in research, education, and diagnostics. The company offers a wide range of PCR reagents optimized for standard, quantitative, and real-time PCR research across human, animal, and plant DNA. Their product lineup includes the rEVAlution qPCR Master Mix, an environmentally friendly hot-start qPCR mixture, and the Taq 2x MeanGreen Master Mix, which provides a ready-to-use solution for efficient PCR amplification. Additionally, Empirical Bioscience supports custom configurations of its products and offers technical assistance for assay and product development. The company, incorporated in 2009, was previously known as Syzygy Biotech Inc. and rebranded in February 2014.

ArborWind is a green energy company that specializes in manufacturing and installing small vertical axis wind turbines. It aims to provide energy to rural areas in an economical and efficient manner. The company’s primary product provides the energy needs of rural areas without the usual costly expenses, transmission losses, and logistics disadvantages. It was founded in 2010 by Frank Fike, James Vincke, and Dilip Nigam. ArborWind is headquartered in Ann Arbor, Michigan.

Reveal Design Automation, Inc. is a start-up based in Ann Arbor, Michigan, specializing in electronic design automation (EDA) software tools aimed at enhancing the formal verification of intricate semiconductor chip designs. Founded in 2009, the company offers Reveal-AV, a product that employs architectural equivalence methodology to ensure comprehensive design verification of various core types, including CPU, MPU, DSP, GPU, and microcontroller RTL against the instruction set architecture (ISA) specifications. Reveal's automated solutions significantly streamline the verification process, enabling tasks that typically take days with other methods to be completed in hours. This efficiency can lead to substantial cost savings for chip designers, reducing verification expenses and accelerating time-to-market, while also bolstering confidence in the accuracy and reliability of chip designs.

zipments is a local logistics platform providing businesses and individuals with the fastest, most affordable same day delivery service available. zipments customers can request local deliveries through www.zipments.com, the zipments mobile app or through a variety of online retailers who have integrated the zipments API with their online shopping carts. zipments serves a variety of sectors including retail, professional service firms and restaurants. Additionally, zipments is an easy to use and affordable solution for consumers in need of assistance with their personal deliveries.

RetroSense Therapeutics is a biotechnology company developing life-enhancing gene therapies designed to restore vision in patients suffering from blindness due to retinitis pigmentosa (RP) and advanced dry age-related macular degeneration (advanced dry-AMD). There are currently no FDA approved drugs to improve or restore vision in patients with these retinal degenerative conditions. The company's approach to using optogenetics in vision restoration is based on pioneering, proprietary research conducted at Wayne State University and Massachusetts General Hospital. Founded in 2009, RetroSense Therapeutics is headquartered in Ann Arbor, Michigan.

NextCAT is commercializing a series of catalysts for use in biodiesel production. With a world class team of catalysis experts, an experienced management team, and industry leading strategic partners, NextCAT sits poised to help turnaround an industry that will not only lessen our dependence on foreign oil, but also improve our environment. Developed at the National Biofuels Energy Lab at Wayne State University, the NextCAT solution allows producers to lower their overall production costs through savings in not only the incoming feedstock but the process as well through fewer process steps and higher efficiency.

Tangent Medical Technologies, a development stage medical device company, was founded in Ann Arbor in 2009 based on technology exclusively licensed from the University of Michigan's Medical Innovation Center. The Company's mission is to improve infusion therapy for patients and healthcare workers with its proprietary, intravenous catheters and associated products. Tangent is led by an experienced, successful management team and the original inventors of the technology. The Company expects to begin generating commercial revenues from its lead product, the NovaCath™ Closed IV Catheter System, in 2012.

Fulcrum Composites Inc is a Michigan based company dedicated to developing new products and bringing them to market. Although their product portfolio is diverse, they are linked by common themes of structural efficiency obtained by synergistic and often unconventional combinations of materials and manufacturing processes.

Armune BioScience, Inc. is a medical diagnostics company based in Kalamazoo, Michigan, focused on developing and commercializing blood tests that utilize the immune system's responses to detect cancer early. Founded in 2007 by members of the Apjohn Group, the company specializes in diagnostic and prognostic tests for prostate, lung, and breast cancers, facilitating personalized treatment decisions for patients and physicians. Its flagship product, APIFINY, is a cancer-specific blood test that assesses the risk of prostate cancer by measuring immune-related biological markers, and is utilized by primary care physicians, urologists, and oncologists. Armune BioScience operates through direct sales to healthcare providers and authorized representatives and has secured exclusive licensing of its technology from the University of Michigan, based on significant research published in reputable medical journals. As of December 2023, Armune operates as a subsidiary of Exact Sciences Corporation.

Inventure Enterprises Inc. is a management consulting and technology services firm based in East Lansing, Michigan, founded in 2002. The company specializes in providing a range of performance solutions, including secure background checks, homeland security, human capital management, and customer relationship management. It also offers information technology application services, encompassing application development and modernization, business intelligence, and mobile applications. One of its key products is idView, a comprehensive background check suite that streamlines the background check process from request to final disposition. Inventure Enterprises serves various sectors, including federal and state government, defense, security, manufacturing, financial services, energy, transportation, and healthcare, both domestically and internationally.

Current Motor Company is based in Ann Arbor, Michigan, and specializes in the development and manufacture of electric motor scooters aimed at urban commuters. The company produces all-electric maxi-scooters that are designed to be fast, fun, and affordable, offering zero-emission transportation solutions. These maxi-scooters can reach speeds of up to 70 MPH and have a range of up to 50 miles, charging conveniently from a standard 110V outlet in approximately five hours. Current Motor sells and services its products through a network of dealers and has formed a strategic partnership with Dakkota Integrated Systems. The company is supported by various investors, including BELLE Capital and the State of Michigan.

NextCAT is commercializing a series of catalysts for use in biodiesel production. With a world class team of catalysis experts, an experienced management team, and industry leading strategic partners, NextCAT sits poised to help turnaround an industry that will not only lessen our dependence on foreign oil, but also improve our environment. Developed at the National Biofuels Energy Lab at Wayne State University, the NextCAT solution allows producers to lower their overall production costs through savings in not only the incoming feedstock but the process as well through fewer process steps and higher efficiency.

InfoReady Corporation, established in 2010 and based in Ann Arbor, Michigan, develops web-based software solutions that streamline workflow and grant application processes for universities. The company's main products include InfoReady Review, which connects researchers with suitable research grants, and InfoReady Thrive, a platform that facilitates access to scholarships, fellowships, and internships. These applications are designed to empower users by enabling them to find relevant information, collaborate with colleagues, and track various activities efficiently. InfoReady serves a diverse range of university sectors, including research offices, academic affairs, and student success services. The company's mission is to simplify the use of business software, ensuring that it enhances productivity rather than hinders it. By offering a seamless, cloud-based solution, InfoReady aims to transform how educational institutions manage information and engage with their communities.

Sentio MMG® is a surgical access tool. It is intended to locate and map motor nerve roots and their peripheral extensions originating from spinal levels C3-T1 and L2-S2. Sentio MMG® smart-sensors are different from all other forms of neuromonitoring electrodes. In contrast to electromyography, or EMG, which relies on needles to detect subtle changes in electrical signals in muscle, Sentio MMG® smart-sensors employ proprietary accelerometer technology. These non-invasive accelerometer-based sensors measure MMG (mechanomyography) activity, or the mechanical “twitch” associated with muscle contraction. When MMG activity is detected, the surgeon is provided with a ‘STOP’ alert indicating a nerve has been identified. The result is an intuitive, surgeon-directed tool for establishing safe access in a variety of surgical applications. Sentio MMG® was specifically designed to facilitate safe lateral transpsoas surgery. Sentio believed there was a better way to identify and map nerves during lateral surgery that did not require EMG. Design objectives included:

Trapelo Health is an Information Technology company focused on precision oncology. Trapelo is an innovative decision support platform that aligns the interests of providers, labs, and payors in the appropriate, scalable use of precision medicine - in real-time.

Mandy & Pandy teaches kids Chinese in a fun and easy way through books, CDs, DVDs, toys, fashion, and television. Similarly, Mandy & Pandy teaches English to Chinese-speaking children.

RealBio Technology, Inc. is a life science product development company based in Kalamazoo, Michigan, founded in 2009. The company specializes in the development and commercialization of advanced cell and tissue culture technologies that support the growth and differentiation of both human and non-human cells. One of its key offerings is the Nth Degree System, a disposable cell culture technology designed to facilitate in vitro cultures that closely mimic natural in vivo cell and tissue development. RealBio Technology aims to provide innovative solutions for scientists and healthcare professionals engaged in life sciences research, enhancing their ability to grow and manipulate cells effectively.

Algal Scientific has two distinct business units that serve the animal feed, human nutrition, and wastewater treatment industries. One unit is focused on the production of their ProGlucan beta-glucan products for animal feeds and human nutrition. The second unit is dedicated to the commercialization of their Hypertrophic wastewater treatment system, which they license to customers in the food and beverage industry. It was acquired by Kemin Industries in March 2017. It was founded in 2017 and is based in Plymouth, Michigan.

Azenic is a dental device company focusing on unmet market needs in the dental profession with emphasis on novel disposable instruments. Axenic Dental was founded in 2008 and is based in Kalamazoo, Michigan.

Michelle's Miracle, Inc., operating under the name Cherry Works, specializes in the production and sale of dietary supplements derived from Montmorency tart cherry concentrate. Founded in 2001 and based in Traverse City, Michigan, the company offers its products in various forms, including concentrates and tablets, aimed at promoting wellness, exercise recovery, muscle and joint relief, and improved sleep. Its offerings are designed to support healthy joint and cartilage function, immune health, cardiovascular health, cognitive performance, and sleep hygiene. Michelle's Miracle markets its products online and through health food stores and grocery retailers across North America. Additionally, the company engages in private label packaging and is actively seeking partnerships for custom supplement formulations. The company was previously known as Leland Cherry Company, Inc. before rebranding in September 2008.

White Pine Systems, LLC (dba SPINN) is dedicated to delivering a complete solution for consumer-engaged healthcare that compliments existing health information technology investments. Their Internet-based patient engagement systems are at the core of the rapidly emerging “connected health” movement. Connected health uses technology to provide access to critical personal health information, improve communication between healthcare providers, patients and their families, and better manage chronic conditions to facilitate living normal lives.

As a provider of workflow enhancing visualization and analysis solutions for cardiology, Epsilon Imaging is transforming cardiac diagnostic workflow with a vendor neutral suite of software applications for echocardiography. EchoInsight assists clinicians with innovative visualization and analysis technologies that enhance, standardize, and streamline analysis, interpretation and trending with echo. Epsilon Imaging offers premier customer support with EchoInsight. The Epsilon Imaging Customer Support Team is comprised of expert technical and clinical specialists that offer rapid and proactive service and training. Echocardiography strain-imaging program consultation is also available. Epsilon Imaging strives to achieve the highest level of satisfaction by partnering with customers to improve efficiency and standardization within their echo programs.

Nymirum, Inc. is a privately held drug discovery company based in Ann Arbor, Michigan, established in 2009. It specializes in developing innovative platforms that target RNA using small molecules. The company's proprietary RNArchitect suite enables the rapid resolution of high-resolution RNA 3D structures, facilitating the identification of new molecules and scaffolds for validated RNA targets. This approach focuses on discovering specific atomic-level RNA conformers that exist in a dynamic ensemble, integrating these findings into the traditional medicinal chemistry and biology pipeline. Nymirum's unique methodology positions it at the forefront of RNA-targeted drug discovery.

OcuSciences is a medical diagnostic device company based in Ann Arbor, Michigan, founded in 2008. The company specializes in developing a non-invasive ocular imaging technique known as flavoprotein fluorescence (FPF), which facilitates the detection and monitoring of retinal metabolic dysfunction. Its key innovation, the Retinal Metabolic Analysis (RMA), allows for the early identification of retinal diseases such as diabetic retinopathy, macular degeneration, and glaucoma, often before irreversible damage occurs. The OcuMet Beacon device captures photographs of the back of the eye while utilizing RMA technology to assess the metabolic health of retinal cells. OcuSciences aims to advance the understanding of ocular manifestations related to diabetes and improve therapeutic approaches for these conditions.

Arbor Photonics, LLC engages in the development of optical-fiber technology and is based in Ann Arbor, Michigan.

Biotectix, LLC specializes in the development and commercialization of bioactive conductive polymer electrodes and coatings designed for medical devices. Founded in 2007 and based in Richmond, California, the company offers innovative products such as Amplicoat, which enhances communication between human tissue and medical device electrodes, and Tecticoat, a conductive coating for textiles and materials. These products are utilized in various medical applications, including retinal and cochlear prostheses, cardiac rhythm management devices, electrophysiology tools, biosensors, wearables, physiological monitoring systems, and deep brain stimulators. Biotectix serves medical device manufacturers, providing durable coatings that improve device stability and long-term electrical performance while addressing challenges like foreign body reactions.

Creative Byline, Inc. provides an online service that enables writers and editors to connect according to their interests and qualifications. Its Website brings together editors from various publishers and enables them to indicate their interests, as well as make a direct connection between the writer and interested editors. The company was founded in 2007 and is based in Holland, Michigan.

Armune BioScience, Inc. is a medical diagnostics company based in Kalamazoo, Michigan, focused on developing and commercializing blood tests that utilize the immune system's responses to detect cancer early. Founded in 2007 by members of the Apjohn Group, the company specializes in diagnostic and prognostic tests for prostate, lung, and breast cancers, facilitating personalized treatment decisions for patients and physicians. Its flagship product, APIFINY, is a cancer-specific blood test that assesses the risk of prostate cancer by measuring immune-related biological markers, and is utilized by primary care physicians, urologists, and oncologists. Armune BioScience operates through direct sales to healthcare providers and authorized representatives and has secured exclusive licensing of its technology from the University of Michigan, based on significant research published in reputable medical journals. As of December 2023, Armune operates as a subsidiary of Exact Sciences Corporation.

Fulcrum Composites Inc is a Michigan based company dedicated to developing new products and bringing them to market. Although their product portfolio is diverse, they are linked by common themes of structural efficiency obtained by synergistic and often unconventional combinations of materials and manufacturing processes.

ERT Systems was founded in 2005 by John Ellis, 25-year veteran firefighter and incident commander, and Dennis Carmichael, owner of a successful IT services company. From his field experience, John knew that managing resources is one of the toughest challenges for an incident commander. He also knew that any solution would have to be completely automatic: responders don’t have time for “overhead” at a chaotic and busy scene. Working with Dennis, the pair came up with a system architecture that could do just that: fully-automatic tracking, locating, and environmental monitoring, in a rapidly-deployable product. ERT Systems was founded to develop that idea into a product. A Beta version was developed and deployed to its first customer, the Macomb College Firefighter Training Facility, in mid-2006.

The 3IS navigation structure is configured specifically for the automotive electronics industry. Linked to the navigation are a multitude of public and private domain industry specific databases. This combination produces the most accurate, comprehensive and relevant search results for technical or commercial data in the global automotive electronics industry.

Aursos, Inc. is a biotechnology company focused on the development of innovative treatments for bone loss. Founded in 2007 and headquartered in Kalamazoo, Michigan, with an additional office in Houghton, Michigan, Aursos is known for its black bear PTH (BB-PTH) 1-34, aimed at preventing and treating osteoporosis, including cases related to chronic immobilization. In addition to its pharmaceutical developments, the company has also created implantable orthobiological technology designed for bone grafting procedures, effectively addressing conditions such as bone voids, non-union fractures, and spinal fusions.

Afid Therapeutics, Inc. develops chemical and biochemical technologies and strategies that are used in the design, discovery, delivery, and development of new drugs. Its products include lactones and esters acids, hydroxy cyclopentane carboxylic acids and derivatives, hydroxy cyclopentane acetic acids and derivatives, amino acids, cyclopentane amino alcohols, cyclopentanones, bicyclic amines and advanced diamines, amino alcohols and diols, unprotected amino diols, diamines, and oxathiolanes and oxazolidinones. The company also involves in the development of a platform of chiral chemical entities to emulate structural, reactive, and physicochemical aspects of biomolecules that potentiate and direct the chemistry of life processes. In addition, it offers ring systems in various screening collections, which include piperazines, oxazolines, oxazolidinones, morpholines, pyrrolidines, pyrrolidones, aza-sugars, macrolides, lactones, lactams, thiolactams, cyclopentanes, furans, pyrans, quinolines, isoquinolines, quinolones, purines, pyridines, pyrimidines, imidazoles, benzimidazoles, triazoles plus many more. Other functionalities include sulfonamides, phosphates, phosphonates, sulfates, sulfonates, alcohols, acids, amines, and oximes, as well as carbohydrate derivatives, nucleoside analogs, and oligosaccharides. The company’s technology base utilizes the structural richness of carbohydrates to allow intervention and therapies across a range of disease spectrum, including bacterial and viral infections, cancer, autoimmune disorders, cardiovascular disorders, diabetes, and Alzheimer's and other neurological disorders. Its drug targets include kinases, phosphatases, nucleases, glycosidases, glycosyltransferases, ribosomes, cell membranes, and nucleic acids. The company was founded in 2003 and is based in Lansing, Michigan.

Global Energy Innovations Inc. provides alternate energy services. The Company manufactures fuel cell energy systems. Global Energy Innovations serves customers worldwide.

Emiliem, Inc. is a private biotechnology company based in San Francisco, California, that specializes in the development of novel oncology therapeutics and treatments for inflammatory and metabolic diseases. The company focuses on understanding the molecular mechanisms that influence the effectiveness of therapeutics and the potential for adverse drug reactions. Emiliem is actively engaged in drug discovery and development, with a portfolio that includes EM101, EM370, and EM400, which target various kinases and cell cycle pathways. Additionally, the company is interested in diagnostic markers for rare diseases and employs computational methods to predict patient outcomes, both positive and negative. Founded in 2005, Emiliem aims to advance therapeutic options through its innovative research and development efforts.

Vestaron Corporation is a biotechnology company that specializes in developing, manufacturing, and selling peptide-based biologic crop protection products. Founded in 2005 and headquartered in Durham, North Carolina, with a research and development center in Kalamazoo, Michigan, Vestaron offers a range of bioinsecticides including Spear-T for thrips in vegetables and ornamentals, Spear-Lep for various fruits and vegetables, and Leprotec for field use. The company's products are designed to enhance the safety, efficacy, and sustainability of agricultural practices while being safe for humans, birds, fish, and pollinators. By utilizing peptides derived from spiders, Vestaron aims to provide innovative solutions for agriculture, animal health, and commercial pest control applications.

iTrack LLC is a developer of autonomous navigation and tracking software designed to accurately monitor personnel and vehicles. The company's technology, funded by the Department of Defense, aims to provide solutions for situations where GPS may not be accessible, allowing users to manage operations from a safe distance. iTrack has established a partnership with Royal Oak Industries, an engineering and manufacturing firm based in Michigan, to facilitate the commercialization of its products. As part of this collaboration, iTrack plans to relocate its operations from the Oakland University Business Incubator to the headquarters of Royal Oak Industries in Lake Orion, Michigan. This move, scheduled for early 2010, will provide iTrack with essential office and engineering space, as well as administrative and financial support to enhance its business development efforts.

Drawing on nearly three decades of experience, The Advisory Board Company serves a membership of more than 2,700 leading hospitals, health systems, universities and other mission-driven enterprises in the United States and, increasingly, worldwide. Our staff is comprised of over 900 researchers, terrain-based experts, hospital administrators, clinicians and consultants, all dedicated to examining the critical issues facing our members and discerning "True North", communicating these insights and best practices with clarity, and providing innovative support such that members can achieve "best in class" performance. We offer an array of professional services—including research, executive education and development, decision-support tools, and consulting—allowing us to target the unique needs of each member institution.

Compendia Bioscience is dedicated to applying the global collection of cancer genomic data to impact patient treatment by enabling the discovery and development and better cancer diagnostics and treatments.

RazorThreat is your trusted solutions to the insidious change in cyber threats. Instead of generalized global operating system or application vulnerability attacks, public and private enterprises are faced with targeted, customized, persistent attacks unique to their environment. Now you can employ a personalized defense to targeted attacks that leverages existing security investments. RazorThreat deploys a Policy-based, Positive Control Communication Profile, which is unique to each client taking the guess-work and complexity out of deepening the security of your network. RazorThreat′s preemptive threat intelligence - highlights unknown and unauthorized activity - identifying both internal and external threats in real time.

Vestaron Corporation is a biotechnology company that specializes in developing, manufacturing, and selling peptide-based biologic crop protection products. Founded in 2005 and headquartered in Durham, North Carolina, with a research and development center in Kalamazoo, Michigan, Vestaron offers a range of bioinsecticides including Spear-T for thrips in vegetables and ornamentals, Spear-Lep for various fruits and vegetables, and Leprotec for field use. The company's products are designed to enhance the safety, efficacy, and sustainability of agricultural practices while being safe for humans, birds, fish, and pollinators. By utilizing peptides derived from spiders, Vestaron aims to provide innovative solutions for agriculture, animal health, and commercial pest control applications.

NRG Dynamix, Inc. is a Michigan-based company specializing in the development of hydraulic hybrid powertrains and advanced hydraulic solutions, including piston accumulators and variable displacement gear pumps. Founded in 2004, the company serves a range of applications such as buses, taxis, commercial transport, and automobiles, and also provides products to the U.S. Department of Defense. NRG Dynamix was formerly known as Hybra-Drive Systems, LLC and has focused on creating energy-efficient technologies for on-highway vehicles, utilizing compressed gas for energy storage. The company has developed and patented several innovations in hydraulic hybrid systems and piston accumulators, positioning itself within the off-highway, marine, alternative fuel, and energy storage markets.

XG Sciences, Inc. is a manufacturer of graphene nanoplatelets, which are advanced carbon nanoparticles derived from graphite. Headquartered in Lansing, Michigan, the company produces xGnP brand graphene nanoplatelets in various thicknesses and diameters for diverse applications across automotive, aerospace, medical, electronics, and energy storage sectors. These nanoplatelets are utilized in polymeric and metallic composites, coatings, and concrete additives, as well as in the formulation of conductive inks and coatings, electrodes, and specialty sheet products. XG Sciences also develops energy storage materials for lithium-ion batteries and provides thermal management solutions, including thermal interface materials. The company serves a global customer base, which includes research organizations, automotive suppliers, and various specialty material companies, and collaborates with partners such as national laboratories and universities. Founded in 2006, XG Sciences enhances product performance through its proprietary manufacturing technology and licensed production capabilities.

Phrixus Pharmaceuticals, Inc. is a biotechnology company focused on developing and commercializing pharmaceutical therapies for heart failure. Based in Ann Arbor, Michigan, the company was incorporated in 2006 and has created Carmeseal, a therapeutic product designed to treat heart failure, particularly in patients with Duchenne muscular dystrophy. This innovative therapy utilizes a polymer to repair muscle damage and aims to improve patient outcomes by providing cost-effective and efficient treatment options for acute heart failure. Through its research and development efforts, Phrixus Pharmaceuticals seeks to address significant healthcare challenges associated with heart failure.

SensiGen is a biotechnology company specializing in gene-based molecular diagnostics. The company focuses on developing and commercializing nucleic acid tests aimed at the early detection of serious diseases, effective monitoring, and reducing overall healthcare costs. SensiGen has a late-stage pipeline featuring high-value diagnostic tests for conditions such as cervical cancer, head and neck cancer, chronic kidney disease, and lupus. These tests are designed to address significant unmet needs in large markets, ultimately enabling healthcare professionals to provide better patient care.

Pixel Velocity creates productive and safe operating environments for businesses and the communities they operate in. It was founded in 2001, is strategically located in Ann Arbor, Michigan, a center for image processing research and the development of advanced sensor technology. Pixel Velocity's technology grew out the Environmental Research Institute of Michigan (ERIM). ERIM’s advanced image processing hardware and software resulted in solutions for the Department of Defense’s imaging problems, including UAV navigation, automatic target recognition, reconnaissance, and surveillance. Pixel Velocity has developed an open architecture video surveillance product that easily layers-in advanced imaging hardware and software developments.