Bio-Techne

Asuragen, Inc. is a molecular diagnostics company based in Austin, Texas, specializing in patient management solutions for oncology and genetic disorders. Founded in 2005, Asuragen focuses on the development and commercialization of diagnostic products for clinical laboratories and pharmaceutical partners. Its product portfolio includes a variety of assays for cancer detection and genetic testing, such as the AmplideX FMR1 PCR reagents for fragile X syndrome and the Signature® line of tests for various cancer mutations. The company utilizes patented technologies, including Armored RNA®, to enhance the accuracy and reliability of its diagnostics. Additionally, Asuragen provides testing services and operates a cGMP manufacturing facility, enabling a comprehensive approach to molecular oncology that encompasses discovery, testing, production, and commercialization. Asuragen's commitment to innovation aids the medical community in improving treatment outcomes through precise diagnostic solutions.

Eminence specializes in the development and manufacturing of chemically-defined media for cell culture, particularly focusing on CHO (Chinese Hamster Ovary) cells. The company has created proprietary products such as EmCD CHO® basal medium and EmCD CHO® Feed, which are designed for various CHO cell lines, including CHO-K1, CHO-S, and CHO-DG44. Eminence offers a comprehensive range of services, including medium formulation development and optimization, tailored to meet the specific needs of its clients in the biopharma sector. With a skilled research and development team and GMP-compliant production facilities, Eminence is committed to delivering high-quality products and flexible solutions, supporting biopharmaceutical companies in adhering to stringent safety and efficacy standards in their processes.

B-MoGen Biotechnologies, based in Saint Paul, Minnesota, specializes in gene editing solutions for various applications, including antibody validation, human disease research, and mitochondrial DNA editing. The company offers a range of services, such as custom vector generation, which includes multi-gene expression vectors delivered via the sleeping beauty transposon system, and custom gene targeting vectors. Additionally, B-MoGen provides genome modification services, including gene knockout, gene knock-in, and the generation of stable transposon cell lines. Their products, including sleeping beauty transposon and transposase vectors, are available for purchase through Neuromics. Since its founding in 2015, B-MoGen has established strategic partnerships with biotechnology firms and completed projects across academia and industry while developing novel intellectual property in the field of genome engineering.

Exosome Diagnostics is developing biofluid-based molecular diagnostic tests for use in personalized medicine. Exosomes and other microvesicles are shed into all biofluids, including blood, urine and cerebrospinal fluid, forming a highly enriched source of intact, disease-specific nucleic acids. The Company's proprietary exosome technology makes use of this natural enrichment to achieve high sensitivity and specificity for rare gene transcripts and the expression of genes responsible for cancers and other diseases.

Quad Technologies is disrupting cell separation and cell therapy workflows by providing researchers with a simple, cell-friendly capture and release technology for cell isolation. Their new MagCloudz™ Streptavidin Cell Separation kit, featuring novel QuickGel™ technology platform, enables straightforward, scalable and fast cell separation with unique magnetic particle dissociation, resulting in complete label free cells. For applications such as T Cell purification, stem cell isolation, circulating tumor cell (CTC) separation and immunotherapy, this unique solution offers drastically improved cell viability, purity and recovery while maintaining a native cellular phenotype.

Astute Medical, Inc. is a life science tools company specializing in the discovery and development of protein biomarkers for rapid diagnosis and risk assessment of acute medical conditions. Founded in 2007 and based in San Diego, California, with a location in Paris, France, the company focuses on validating prognostic biomarkers related to conditions such as abdominal pain, acute coronary syndromes, cerebrovascular injury, kidney injury, and sepsis. Its primary product, NephroCheck, is a single-use cartridge designed to detect biomarkers of acute kidney injury, while the Astute140 meter converts the fluorescent signals from the NephroCheck cartridge into a single numerical result. Astute Medical's products are marketed in the United States and Europe and aim to enhance clinical decision-making and patient outcomes. As of April 2018, Astute Medical operates as a subsidiary of bioMérieux S.A.

Advanced Cell Diagnostics, Inc. specializes in developing and commercializing cell and tissue-based diagnostic tests aimed at advancing personalized medicine. The company employs its proprietary RNAscope technology, which enables the detection and quantification of RNA biomarkers at single-molecule sensitivity through multiplex fluorescent and chromogenic in situ hybridization. Its product offerings include manual assays, reagent kits, and catalog probes, as well as software for quantitative analysis of RNA samples and instruments for manual assay workflows. Advanced Cell Diagnostics also provides pharmaceutical assay services to facilitate understanding of disease mechanisms in preclinical research, target validation, and clinical trials. Additionally, the company has a companion diagnostic assay development program to optimize the assay development process. Its products are distributed through various channels, including international markets, and are also available for online purchase. Founded in 2007 and located in Hayward, California, the company operates as a subsidiary of Bio-Techne Corp.

Space Import Export S.r.l. is a distribution company that has been working in the Life Science business since 1985, specialized in the fields of Biomedical Research and Diagnostic Market. Our distribution activity has grown, through an active cooperation with a sister company, called LaboSpace, provider of laboratory services, with branches in Italy, UK and USA.

Zephyrus Biosciences, Inc. is a life science research tools company based in Berkeley, California, founded in 2013. The company specializes in the development and commercialization of innovative research tools that facilitate protein analysis at the single-cell level. Its flagship product, the scWestern System, allows for western blotting on individual cells, a significant advancement in the field of single-cell analysis. This system employs microfluidics technology to isolate single cells in micro-wells, lysing them and performing SDS-PAGE separation on each lysate. Researchers utilize Zephyrus's tools to explore critical areas such as cancer biology, stem cell research, neurology, and broader human disease studies, ultimately contributing to advancements in diagnostics and therapeutics. As of March 2016, Zephyrus operates as a subsidiary of Bio-Techne Corp.

CLINIQA Corp is specializes in the manufacturing and commercialization of quality controls and calibrators. For over 40 years, CLINIQA has earned an enviable track record within the IVD industry by manufacturing and marketing high quality products, designed to improve the accuracy of diagnostic tests. CLINIQA operates from facilities in San Diego County in Southern California. CLINIQA's Quality Management Systems are compliant with the FDA QSR and certified to EN ISO 13485:2012 and ISO 13485:2003 standards. CLINIQA specializes in the supply of reagents, controls, calibrators, calibration verifiers, proficiency test materials, biologicals and contract manufacturing services. Liquid QC® products from CLINIQA feature the benefits of "ready-to-use" convenience, 30-day open vial stability, and a 24-36 month shelf life when refrigerated. With total dedication to quality and a unique focus on liquid stablization techology, CLINIQA's products consistently meet market demands for stability, convenience, and reproducibility.

CyVek, Inc. is a company based in Wallingford, Connecticut, focused on developing a technology platform designed to measure analytes in biological samples. Incorporated in 2008, CyVek provides an integrated test system that features a microfluidic cartridge, enabling the analysis of multiple biomarkers from minimal volumes of biological materials. This innovative approach facilitates efficient and accurate measurement, contributing to advancements in the field of diagnostics.

Novus Biologicals, LLC is dedicated to accelerating scientific discovery by developing and marketing specialized products for the life sciences sector. The company offers a wide range of research tools, including primary and secondary antibodies, peptides, proteins, kits, controls, lysates, RNAi, and other reagents essential for life science research. These products aid in the study of protein functions across various fields, such as cancer, neuroscience, autophagy, and cardiovascular research. Novus Biologicals focuses on monitoring scientific trends to ensure the availability of relevant materials and provides detailed technical information and ongoing support to researchers. By catering to both niche and emerging markets, Novus Biologicals fosters strong partnerships with its customers, ultimately contributing to the advancement of biological research.

ProteinSimple is part of the Protein Platforms division of Bio-Techne (NASDAQ: TECH). They rethinking protein tools and helping thousands of researchers around the world resolve their protein analysis problems so they can reveal new insight into proteins and their role in disease. Their wide-ranging portfolio of tools includes everything from immunoassay systems that quantify protein expression to systems that probe the structure and purity of protein-based therapeutics.

Shanghai PrimeGene Bio-Tech Co is a leader in the China market in the development, manufacture and distribution of recombinant proteins for research and diagnostic applications.

CyVek, Inc. is a company based in Wallingford, Connecticut, focused on developing a technology platform designed to measure analytes in biological samples. Incorporated in 2008, CyVek provides an integrated test system that features a microfluidic cartridge, enabling the analysis of multiple biomarkers from minimal volumes of biological materials. This innovative approach facilitates efficient and accurate measurement, contributing to advancements in the field of diagnostics.

Bionostics is a world-leading developer and manufacturer of high quality, turnkey calibrators and quality control products for original equipment manufacturers (OEMs) for critical care / point-of-care and diabetes diagnostics test systems. Located in Devens, Massachusetts, Bionostics offers a variety of services to provide high quality, cost effective, turn-key solutions to our customers, large and small. We maintain professional associations with customers and suppliers, striving to work together in relationships that are beneficial for all parties. As a key partner to world-class OEMs, we are acutely aware of our responsibility to maintain and foster the brand identities of our clients. Our quality systems are certified to ISO 9001:2008 and 13485:2003. Our products are listed as Class I and Class II with the US FDA, bear Class II and Class III Medical Device Licenses in Canada and fully comply with requirements of 98/79/EC, the In-Vitro Diagnostics Directive.

Tocris Holdings is a supplier of reagents for non-clinical life science research.

ChemoCentryx focuses on discovery, development and commercialization of orally-administered small molecule therapeutics that target chemokine receptors and related chemo-attractant receptors. Their small molecule product candidates is designed to target a specific chemokine or chemo-attractant receptor, thereby blocking the inappropriate immune system cascade underlying a given disease.