The National Science Foundation (NSF), established in 1950 and located in Alexandria, Virginia, is an independent federal agency dedicated to advancing fundamental research and education across all scientific and engineering disciplines. With an annual budget of approximately $7.8 billion, the NSF operates America's Seed Fund, which allocates nearly $200 million each year to support startups and small businesses through the Small Business Innovation Research (SBIR) program. This initiative provides non-dilutive funding of up to $1.5 million to assist in research and development efforts, thereby facilitating the transformation of scientific discoveries into commercially viable products and services. By helping to de-risk technology, the NSF plays a crucial role in fostering innovation and addressing societal challenges through scientific advancements.
Rift Valley provides solutions for addressing burnout, turnover, and mental health disruption within the workplace. They provide management with a holistic dashboard and suite of tools. They are changing that model and offering institutions the means to prioritize their people effectively.
Aspero Medical, Inc. is a medical device manufacturer based in Boulder, Colorado, established in 2018. The company specializes in gastrointestinal balloon endoscopy procedures, offering a product known as the AP Balloon Overtube. This innovative device utilizes pillar micro-texture technology to improve the performance of endoscopic procedures by enhancing mucosal wall traction and anchoring consistency within the gastrointestinal tract. By optimizing these aspects, Aspero Medical aims to reduce procedure time and sedation requirements, ultimately improving patient outcomes and providing cost-effective solutions for healthcare providers.
University of Colorado Boulder is a bold, innovative community of scholars and learners who accelerate human potential. University of Colorado Boulder, colloquially referred to as CU or Colorado, is a public research university in Boulder, Colorado. It is the flagship university of the University of Colorado system, and was founded in 1876, five months before Colorado became a state.
Green Sun Medical, LLC is a medical device company established in 2013 and located in Fort Collins, Colorado. The company specializes in the design, development, and manufacturing of orthotic braces aimed at treating Adolescent Idiopathic Scoliosis (AIS) and Kyphosis. Its innovative products are designed to correct spinal deformities, providing support and alignment for patients with these conditions.
Skyhaven Systems is a specialty research and development firm that focuses on solving critical US Government needs in the Defense, Energy, Aerospace, and Environmental sectors. With the firm’s headquarters located in Steamboat Springs, CO and its main research and development laboratories located in Westford, MA, the firm applies advanced electrochemical engineering and science principles to solve technical problems of concern to the Government including the Department of Defense, NASA, Environmental Protection Agency, National Science Foundation, Department of Energy, USDA, NIH, and the Centers for Disease Control. Skyhaven Systems is a privately held limited liability company formed in 2017 that merged its former business, Reactive Innovations, LLC, into its new operations. The Firm owns a 4200 ft2 facility in Westford, MA where it conducts its primary research and development activities along with light manufacturing. Skyhaven conducts innovative research and development work in the chemical process technology area focusing on reaction chemistry, reactor design, separation systems, sensors, thermal management, and materials development. At the core of their technologies is a reaction-based chemical process used to fabricate the product, or that the product uses to conduct its operation. Skyhaven’s mission is to explore, develop, and commercialize novel chemical and electrochemical-based systems that larger organizations are disinterested in developing due to small market sizes, high risk, or lengthy development times that can be counter to meeting short-term profit margin goals. Skyhaven seeks out high risk development areas via responding to competitive solicitations and securing government funded contracts and grants. These contracts enable the firm to innovate and develop new technologies to solve government identified problems culminating in the delivery of research reports, operational prototypes, or a limited number of operational systems for use by the government. As a small business, Skyhaven owns the technology rights to its government funded research and development projects. The government receives a royalty-free license to use the technology for its needs while Skyhaven is free to commercialize the technology toward non-government needs. Consequently, the firm files patents and establishes trade secrets on select technologies to protect core development areas that are being primed for commercialization.
Contextualize provides the tools needed to capture the expertise spread across an organization and make it accessible and usable to others across the organization. It also leverages mathematical descriptions of complex phenomena and machine learning models to extract physics from the latter and models from the former, enabling clients to transform the wealth of information into actionable insights.
LumenAstra, founded in 2020 and headquartered in Longmont, Colorado, develops non-invasive, wearable deep-tissue temperature sensors aimed at enhancing patient care in various medical contexts. The company's innovative technology allows for the external measurement of internal temperature, making it particularly useful in cancer hyperthermia therapy. Additionally, LumenAstra's sensors have applications in monitoring hypothermia during aortic dissection repair, brain temperature in neonatal hypoxia-ischemia cases, and internal heat stress in military and hazardous environments. This technology enables medical professionals to effectively protect patients from serious injuries and fatalities related to heat stress.
DrivenData focuses on leveraging data science and crowdsourcing to address significant social challenges. The company organizes online challenges, typically lasting 2-3 months, where a global community of data scientists competes to develop effective statistical models for complex predictive problems. In addition to these competitions, DrivenData offers services that include comprehensive data assessment, predictive modeling, statistical analysis, and rapid development and prototyping. By connecting mission-driven organizations with skilled data scientists, DrivenData aims to empower these organizations to make impactful decisions based on their data.
Intersphere, founded in 2020 and headquartered in Fort Collins, Colorado, specializes in providing environmental services, focusing on weather and climate forecasts for seasonal to decadal planning horizons. The company employs a combination of artificial and human intelligence to deliver accurate predictions, helping clients manage risks related to weather and climate. Intersphere's services cater to various sectors, including natural resource management, energy, and agriculture, enabling clients to make informed decisions based on optimized forecasts.
Grid7
Grant in 2021
Grid7’s project, E-Blockchain: A Scalable Platform for Secure Energy Transactions and Control, aims to use blockchain technology to address power plant cybersecurity issues and explore how a decentralized approach can improve the reliability of energy networks.
Terra Cover is a monitoring platform operator based in Denver, Colorado, specializing in applications for insurance and water resource management. Founded in 2020, the company utilizes data, machine learning, and physics to provide insights into the Earth's constantly changing surface. Its platform enables businesses to analyze satellite imagery and geospatial data at scale, facilitating improved decision-making in resource management and risk assessment.
Cobio Diagnostics is a biotechnology company that develops diagnostics for bacterial identification and phenotypic antibiotic resistance testing. The company was established in 2016 and is based in Golden, Colorado.
Vapor Cell Technologies, founded in 2020 and based in Boulder, Colorado, specializes in the development of ultra-compact vapor cells that achieve sub-nanometer precision in distance measurement. These innovative vapor cells convert lasers into wavelength standards, facilitating accurate measurements of length and optical frequency. By providing advanced sensing capabilities, the company supports various industries and laboratories in their efforts to advance atomic technology and enhance precision in scientific research and applications.
ElectraSteel uses intermittent renewable energy for the electrification and decarbonization of iron and steelmaking. ElectraSteel's investors include leading sustainability-focused global venture capital funds with $300B+ assets under management.
Tortuga AgTech focuses on enhancing agricultural practices through the development of digital horticulture systems that integrate robotics, automation, precision data analytics, and machine learning. By automating labor-intensive tasks such as picking, packing, and trimming, Tortuga AgTech aims to significantly reduce the manual labor required in farming while increasing yields through optimized growing conditions. The company's mission is to promote a healthier society and a thriving ecosystem by empowering growers to produce unique, nutritious food that is environmentally sustainable. This approach not only helps farmers compete with large-scale agriculture but also fosters the creation of local technical jobs. Ultimately, Tortuga AgTech strives to provide fresher and healthier products to communities near their grower clients.
Manufaturer of environmental sampling products intended to simplify the sample collection process. The company's system creates ultrasonic personal air sampler and water sampling products for environment analysis, enabling researchers and industrial hygienists to monitor particulates and pollutants in the work environment and perform fixed measurements within one device.
Aspero Medical, Inc. is a medical device manufacturer based in Boulder, Colorado, established in 2018. The company specializes in gastrointestinal balloon endoscopy procedures, offering a product known as the AP Balloon Overtube. This innovative device utilizes pillar micro-texture technology to improve the performance of endoscopic procedures by enhancing mucosal wall traction and anchoring consistency within the gastrointestinal tract. By optimizing these aspects, Aspero Medical aims to reduce procedure time and sedation requirements, ultimately improving patient outcomes and providing cost-effective solutions for healthcare providers.
Cloud services have become ubiquitous to all major 21st century economic activities. However, cloud services and technologies can be significantly more powerful than they are now. A persistent barrier to further advancement has been the lack of a large-scale and open cloud research platforms. With funding from the National Science Foundation (NSF), the Chameleon project will provide such a large-scale platform to the open research community allowing them explore transformative concepts in deeply programmable cloud services, design, and core technologies. Chameleon will allow users to explore problems ranging from the creation of Software as a Service to kernel support for virtualization. This broad range of supported research includes many other areas such as developing Platforms as a Service, creating new and optimizing existing Infrastructure as a Service components, investigating software-defined networking, and optimizing virtualization technologies. The Chameleon testbed, will be deployed at the University of Chicago and the Texas Advanced Computing Center and will consist of 650 multi-core cloud nodes, 5PB of total disk space, and leverage 100 Gbps connection between the sites. While a large part of the testbed will consist of homogenous hardware to support large-scale experiments, a portion of it will support heterogeneous units allowing experimentation with high-memory, large-disk, low-power, GPU, and co-processor units. The project will also leverage existing FutureGrid hardware at the University of Chicago and the Texas Advanced Computing Center in its first year to provide a transition period for the existing FutureGrid community of experimental users. To support the broad range of experiments experiments described above, the project will support a graduated configuration system allowing full user configurability of the software stack, from provisioning of bare metal and network interconnects to delivery of fully functioning cloud environments. A special feature of Chameleon is that it provides for an exceptionally close integration of clouds and networks, which substantially enhances the capabilities of both. In addition, to facilitate experiments, Chameleon will support a set of services designed to meet researchers needs, including support for experimental management, reproducibility, and repositories of trace and workload data of production cloud workloads. The project is led by the Computation Institute at the University of Chicago and partners from the Texas Advanced Computing Center at the University of Texas at Austin, the International Center for Advanced Internet Research at Northwestern University, the Ohio State University, and University of Texas at San Antonio, comprising a highly qualified and experienced team. The team includes members from the NSF supported FutureGrid project and from the GENI community, both forerunners of the NSFCloud solicitation under which this project is funded. Chameleon will also form a set of partnerships with commercial and academic clouds, such as Rackspace, CERN and Open Science Data Cloud (OSDC), and will partner with other testbeds, notably GENI and INRIA's Grid'5000 testbed.
Imagine a solution that understands an athlete’s life beyond their training. A solution that knows how many last-minute, unexpected work, family, and friends things can come up in a week. Imagine how happy coaches would be to free themselves from the manual work of inputting data and focus on the morale of their athletes instead.
Impressio is a manufacturer specializing in the development of ultra-dissipative materials designed to enhance human health and safety through innovative applications. The company focuses on creating advanced liner materials for protective equipment, such as helmet liners and padding, by utilizing liquid-crystal elastomers. These novel materials aim to address existing challenges in energy absorption associated with traditional helmet foams, thereby reducing the risk of concussions and improving head protection. Impressio's products have potential applications across various sectors, including sports, military, automotive, and aerospace.
Meati, also known as Emergy Foods, is a consumer goods company based in Boulder, Colorado, founded in 2016. The company specializes in producing whole muscle, nutritious plant-based meats designed to promote healthier lifestyles and environmental sustainability. By utilizing proprietary, clean technologies, Meati offers nutrient-dense meat alternatives that aim to appeal to a wide audience, ensuring that consumers can enjoy meals that are both good for their health and the planet.
Developer and manufacturer of aerosol particle collector devices designed to revolutionize the science of airborne particle sampling for physical, chemical and biological analysis. The company's collectors provide pre-concentrated samples, with better collection efficiency and offer efficient aerosol measurement capabilities that advance scientific knowledge, that lead to improving the environment, health, safety, and quality of life, enabling researchers to enhance their aerosol research with time-resolved and concentrated particle samples.
Biomimicry Design Alliance is a consulting organization that aims to make biomimicry more accessible to the architecture community. The company was founded in 2018 and is based in Denver, Colorado.
Alligant Scientific
Grant in 2020
Provider of services in energy and materials science industry. The company provides technological services for solving technical issues in the field of energy and materials science. The company was incorporated in 2013 and is based in Highlands Ranch, Colorado.
ClearSight develops intraocular lenses for high-quality vision after cataract surgery. The company was founded in 2012 and is headquartered in Aurora, Colorado.
Grid7
Grant in 2020
Grid7’s project, E-Blockchain: A Scalable Platform for Secure Energy Transactions and Control, aims to use blockchain technology to address power plant cybersecurity issues and explore how a decentralized approach can improve the reliability of energy networks.
Green Sun Medical, LLC is a medical device company established in 2013 and located in Fort Collins, Colorado. The company specializes in the design, development, and manufacturing of orthotic braces aimed at treating Adolescent Idiopathic Scoliosis (AIS) and Kyphosis. Its innovative products are designed to correct spinal deformities, providing support and alignment for patients with these conditions.
Provider of a geospatial remote sensing and hydro spatial data service based in Denver, Colombia. The company provides hydro spatial products, Earth observation analysis services, and Satellite-Derived Bathymetry data for near-shore areas around the globe, enabling research and government agencies to run hydrographic surveys easily.
Meati, also known as Emergy Foods, is a consumer goods company based in Boulder, Colorado, founded in 2016. The company specializes in producing whole muscle, nutritious plant-based meats designed to promote healthier lifestyles and environmental sustainability. By utilizing proprietary, clean technologies, Meati offers nutrient-dense meat alternatives that aim to appeal to a wide audience, ensuring that consumers can enjoy meals that are both good for their health and the planet.
Developer and manufacturer of aerosol particle collector devices designed to revolutionize the science of airborne particle sampling for physical, chemical and biological analysis. The company's collectors provide pre-concentrated samples, with better collection efficiency and offer efficient aerosol measurement capabilities that advance scientific knowledge, that lead to improving the environment, health, safety, and quality of life, enabling researchers to enhance their aerosol research with time-resolved and concentrated particle samples.
NeuDax offers a wide range of artificial intelligence (AI) solutions to upstream oil and gas (O&G) industry. The NeuDax "Analytics and Software-as-a-Service" (A+SaaS) solution provides both AI-Platforms and engineering and technical consults to clients to help them improve their decision making in the unconventional oil and gas projects. The NeuDax solution is beyond limited machine learning (ML) applications. We provide solutions based on cutting-edge technologies, including deep learning (DL) and reinforcement learning (RL), to maximize the advantage of big data to oil and gas operators.
Swift Solar Inc. is a U.S.-based company specializing in the design and manufacture of lightweight, flexible solar panels. Founded in 2017 and headquartered in San Carlos, California, with an additional facility in Golden, Colorado, the company focuses on advanced photovoltaic technology utilizing perovskite semiconductors. Swift Solar's products are engineered for diverse applications, including aerospace, automotive, and building sectors. The team comprises experts from prestigious institutions such as Stanford, MIT, and the University of Washington, who leverage their knowledge to develop innovative solar cell architectures and specialized manufacturing techniques. Swift Solar's ultra-thin perovskite films are designed for high efficiency, enabling the production of tandem solar cells that maximize light absorption and conversion efficiency while maintaining a low weight.
Vartega is a technology development company focused on recycling carbon fiber reinforced plastics, specifically through its innovative patent-pending processes. Established in 2014 and located in Golden, Colorado, Vartega aims to provide low-cost carbon fiber for various mass market applications across several industries, including aerospace, automotive, wind energy, and sporting goods. The company produces recycled carbon fiber suitable for use in nonwoven fabrics, thermoplastic pellets, yarns, and 3D printing filaments. By developing alternative recycling technologies and equipment, Vartega seeks to contribute to the sustainability of carbon fiber materials and enhance their accessibility for broader applications.
Robotic Materials provides solutions to improve efficiency in manufacturing and e-commerce by leveraging robotic AI. The company develops general purpose mobile manipulators that combine the power of deep learning with semantic reasoning to perform mobile bin picking, kitting, and assembly.
Alef is an app for teaching, learning, and doing math that provides a visceral connection to an equation through touch, and a unique way of communicating abstract concepts on mobile devices.
Stateless, Inc. specializes in providing innovative network architecture solutions for organizations utilizing private or hybrid cloud infrastructures. Founded in 2016 and headquartered in Boulder, Colorado, the company offers a software-defined interconnect network platform known as Luxon, which enables colocation providers to deliver dynamic routing, security, and automation services at network interconnection points. Stateless focuses on enhancing connectivity by allowing providers to control and connect various endpoints, including data centers, tenant sites, and hyperscale clouds. Through its enterprise software platform, Stateless integrates scalable, fault-tolerant network functions with virtualization capabilities, facilitating the creation of multi-tenant connectivity services that are flexible, scalable, and cost-effective for cloud service providers.
Robotic Materials provides solutions to improve efficiency in manufacturing and e-commerce by leveraging robotic AI. The company develops general purpose mobile manipulators that combine the power of deep learning with semantic reasoning to perform mobile bin picking, kitting, and assembly.
ClearSight develops intraocular lenses for high-quality vision after cataract surgery. The company was founded in 2012 and is headquartered in Aurora, Colorado.
MRX Analytics specializes in solving problems that require 3D temperature measurements in an MRI or other magnetic resonance imaging system. The company was founded in 2017 and is headquartered in Colorado Springs, CO.
Geospiza is a tech startup that changes the way crisis and emergency management decisions are made. The Geospiza software platform integrates real-time IoT, big data, advanced analytics, and evidence-based consequence projections to support decision making that saves lives and protects the environment.
Tortuga AgTech focuses on enhancing agricultural practices through the development of digital horticulture systems that integrate robotics, automation, precision data analytics, and machine learning. By automating labor-intensive tasks such as picking, packing, and trimming, Tortuga AgTech aims to significantly reduce the manual labor required in farming while increasing yields through optimized growing conditions. The company's mission is to promote a healthier society and a thriving ecosystem by empowering growers to produce unique, nutritious food that is environmentally sustainable. This approach not only helps farmers compete with large-scale agriculture but also fosters the creation of local technical jobs. Ultimately, Tortuga AgTech strives to provide fresher and healthier products to communities near their grower clients.
Microbial Pulse Diagnostics
Grant in 2019
Microbial Pulse Diagnostics is developing and deploying an innovative NIST technology for the rapid measurement of antimicrobial susceptibility. This technology “takes the pulse” of bacterial cells, sensing changes in their metabolism, motility, and growth after exposure to an effective antibiotic.
Meati, also known as Emergy Foods, is a consumer goods company based in Boulder, Colorado, founded in 2016. The company specializes in producing whole muscle, nutritious plant-based meats designed to promote healthier lifestyles and environmental sustainability. By utilizing proprietary, clean technologies, Meati offers nutrient-dense meat alternatives that aim to appeal to a wide audience, ensuring that consumers can enjoy meals that are both good for their health and the planet.
Alligant Scientific
Grant in 2018
Provider of services in energy and materials science industry. The company provides technological services for solving technical issues in the field of energy and materials science. The company was incorporated in 2013 and is based in Highlands Ranch, Colorado.
Provider of a geospatial remote sensing and hydro spatial data service based in Denver, Colombia. The company provides hydro spatial products, Earth observation analysis services, and Satellite-Derived Bathymetry data for near-shore areas around the globe, enabling research and government agencies to run hydrographic surveys easily.
MusiQuest is a music application developed by Edify Technologies, Inc. aimed at helping children explore their passion for music through engaging games and educational content. The application features interactive adventures and animal characters that introduce fundamental musical concepts, guiding kids in the process of composing their own music. MusiQuest provides a platform where young users can learn, improve, and create music in various styles, making the learning experience enjoyable and accessible. Founded in 2015 and based in Denver, Colorado, Edify Technologies, Inc. also offers other music-related applications, including Sketch-a-Song and Opus, which cater to both children and music educators.
Rebound Technologies, Inc. manufactures and supplies embedded thermal energy storage systems for commercial freezer environments and off-grid cooling environments. It offers IcePoint, a low temperature refrigeration cooling equipment for supermarkets; and SunChill, an off-grid refrigeration solution that enables increased agricultural productivity by removing field heat from crops immediately following harvest, and provides continued product cooling at local markets and central processing facilities. The company’s products are used by retail stores and farmers in the United States. Rebound Technologies, Inc. was founded in 2012 and is headquartered in Commerce City, Colorado.
Elementum 3D, Inc. is a research and development company based in Erie, Colorado, specializing in additive manufacturing. Founded in 2014, it focuses on the creation of advanced materials, including metals, composites, and ceramics specifically designed for the 3D printing industry. The company produces a variety of products such as aluminum Metal-Matrix Composites, tungsten, copper, nickel and steel Metal-Matrix Composites, nickel titanium, and cemented carbide. These materials are engineered to withstand high loads while providing resistance to abrasion, heat, oxidation, and corrosion. Elementum 3D aims to meet the growing demands of the printing industry by delivering high-quality materials that enhance performance and reliability.
Quest Thermal Group is a technology and product development engineering firm, specializing in the design and development of advanced thermal insulation systems. Quest Thermal focuses on developing and bringing to market advanced, next generation, structural thermal insulation solutions for aerospace and commercial applications. Their solutions achieve lower mass and enhanced thermal performance with discrete patented spacer technology. They are creative, inventive, capable engineers and scientists, with extensive thermal insulation expertise, R&D experience, and a product-centric vision. Quest Thermal has developed multiple advanced insulation systems, for aerospace and commercial applications. These customizable engineering solutions can be used for insulating spacecraft, launch vehicles, high turndown variable radiators, vapor cooling, ISRU liquefaction storage tanks, dewars, LNG carriers and tanks, and appliances such as refrigerators.Quest's high performance Integrated Multi-Layer Insulation (IMLI) is in space insulating the flight dewar for NASA's Robotic Refueling Mission 3 on the ISS, and is at TRL9. IMLI will fly on the NASA/Ball Aerospace Green Propellant Infusion Mission on the June 2019 Flacon 9 Heavy flight, and IMLI is in early design for the NASA Lucy spacecraft to Jupiter's Trojan asteroids. Quest Load Bearing MLI supported a Broad Area Cooled shield in the NASA Reduced Boiloff 2 experiment, and led to a successful test program aimed at achieving Zero Boil Off of cryogenic propellants.
2B Technologies is dedicated to the development and commercialization of new analytical instruments for atmospheric and environmental measurements. They specialize in miniaturized instruments for measurements of ozone (O3), nitric oxide (NO), nitrogen dioxide (NO2), mercury (Hg; under development), and other chemical species in air. The photo to the right shows their Model 202 Ozone Monitor and their Personal Ozone Monitor (POM) sitting atop a conventional ozone monitor. Their Model 202 was originally developed out of the need for the University of Colorado research group of co-founder Dr. John Birks to make vertical profiling measurements of ozone on kites and balloons where measurements using conventional ozone monitors are impossible. The POM represents another advance in miniaturization and portability. Their small, lightweight, low-power instruments are now used for atmospheric measurements using balloons, kites, UAVs, research aircraft, and at many remote sites, including Antarctica, the Galapagos Islands, the Greenland ice sheet, the summit of Mont Blanc, the Amazon rain forest, on buoys in the Arctic Ocean, on commercial airliners, in many U.S. National Parks and at numerous other locations throughout the world. More than 1,700 of Their Model 202 and Model 205 Ozone Monitors, over 140 POMs, and more than 4,100 total instruments have been sold since the year 2000, with about half of their instruments going to researchers outside the U.S. More than 500 scientific papers have been published that cite use of 2B Tech instruments, and those papers have been cited more than 7,000 times by other researchers.
Robotic Materials provides solutions to improve efficiency in manufacturing and e-commerce by leveraging robotic AI. The company develops general purpose mobile manipulators that combine the power of deep learning with semantic reasoning to perform mobile bin picking, kitting, and assembly.
Big Blue Technologies specializes in high-temperature thermal processes for upgrading the value of minerals and ores into metals and ceramics. Currently, BBT is developing a thermal magnesium metal production process.
LightStanza, a startup located in Boulder, Colorado, specializes in daylight simulation software designed for the construction industry. The company offers a web application that provides a comprehensive analysis of daylighting, which is often overlooked in building design. LightStanza's software utilizes cloud computing to deliver features like point-in-time rendering, illuminance grid animations, and multiple annual analyses, along with tools for LEED scorecards and glare reports. This enables architects, lighting consultants, and sustainable design specialists to generate accurate reports that simulate daylight conditions throughout the year. By focusing specifically on daylighting, LightStanza aims to enhance energy efficiency and improve the overall design of spaces, acknowledging the complexity of light as a dynamic element in architecture.
DMC Biotechnologies, Inc. is a biotechnology company based in Boulder, Colorado, focused on developing bio-based products through microbial fermentation technology. The company specializes in the production of specialty chemicals, flavors, fragrances, nutraceuticals, and pharmaceuticals. By utilizing Dynamic Metabolic Control technology, DMC aims to streamline the production process, reducing both costs and development timelines from discovery to commercial viability. Founded in 2014, DMC Biotechnologies is dedicated to creating sustainable manufacturing solutions that utilize lower energy and resources, contributing to a more sustainable economy.
Developer and manufacturer of aerosol particle collector devices designed to revolutionize the science of airborne particle sampling for physical, chemical and biological analysis. The company's collectors provide pre-concentrated samples, with better collection efficiency and offer efficient aerosol measurement capabilities that advance scientific knowledge, that lead to improving the environment, health, safety, and quality of life, enabling researchers to enhance their aerosol research with time-resolved and concentrated particle samples.
MVSystems designs, builds and delivers world-class ultra-high vacuum (UHV) single and multi-chamber deposition systems for R&D, prototype production and small production lines. As part of the systems sales, we specifically guarantee state of the art opto-electronic properties of thin film semiconductors such as amorphous and nanocrystalline silicon, dielectrics and transparent conductive oxides (TCOs).
Alef is an app for teaching, learning, and doing math that provides a visceral connection to an equation through touch, and a unique way of communicating abstract concepts on mobile devices.
Stateless, Inc. specializes in providing innovative network architecture solutions for organizations utilizing private or hybrid cloud infrastructures. Founded in 2016 and headquartered in Boulder, Colorado, the company offers a software-defined interconnect network platform known as Luxon, which enables colocation providers to deliver dynamic routing, security, and automation services at network interconnection points. Stateless focuses on enhancing connectivity by allowing providers to control and connect various endpoints, including data centers, tenant sites, and hyperscale clouds. Through its enterprise software platform, Stateless integrates scalable, fault-tolerant network functions with virtualization capabilities, facilitating the creation of multi-tenant connectivity services that are flexible, scalable, and cost-effective for cloud service providers.
Boulder Environmental Sciences and Technology (BEST) is developing several new radiometers for environmental monitoring: a Profiling Radiometer for Atmospheric and Cloud Observation PRACO, a Marine Profiling Radiometer MPR, and an Autonomous Profiling Radiometer. These instruments use novel design approaches that aim to remove the user completely from supervision and allow all-weather operation, data collection, and retrievals. In cooperation with the Atmospheric and Environmental Research (AER) they are working on a design of a Hyperspectral Microwave Sensor.
MusiQuest is a music application developed by Edify Technologies, Inc. aimed at helping children explore their passion for music through engaging games and educational content. The application features interactive adventures and animal characters that introduce fundamental musical concepts, guiding kids in the process of composing their own music. MusiQuest provides a platform where young users can learn, improve, and create music in various styles, making the learning experience enjoyable and accessible. Founded in 2015 and based in Denver, Colorado, Edify Technologies, Inc. also offers other music-related applications, including Sketch-a-Song and Opus, which cater to both children and music educators.
Symbios Technologies is commercializing its disruptive advanced low-cost aqueous plasma oxidation technology, the Symbios Tubular Plasma Reactor, to clean water, preserve the environment, and protect human health.
PlayPosit, Inc. operates an online learning platform that allows users to create and share interactive video lessons, transforming passive video content into engaging learning experiences. Founded in 2012 and based in Washington, D.C., PlayPosit serves both educational institutions and corporate clients, facilitating training for employees, partners, and customers. The platform supports various learning environments, including K-12, flipped classrooms, and blended learning settings. Users can enhance videos from sources such as TED and Khan Academy with interactive elements like quizzes, annotations, and peer reviews, enabling educators and trainers to monitor and assess learner engagement and understanding effectively. PlayPosit was previously known as eduCanon Inc. and rebranded in 2016. The company has received backing from notable organizations, including AT&T and Stanford’s startX, and has been recognized as a leading open educational resource.
Lupine Labs specializes in the design, development, and integration of automated manufacturing processes. Thier expertise is in material science and machine automation, two skill sets that work well with cutting edge manufacturing. They work with manufacturing teams to develop and build production ready tools that push the limits of science and technology.
Xerion Advanced Battery develops nanotechnology-based, high-power, and high-energy battery systems. While advancement in battery technology has been steady, most of this advancement has been evolutionary in nature, based upon refinement in electrode materials and chemistries, and incremental advances in electrolyte stability. However, even with these advances, today’s commercial batteries still exhibit slow charging, inadequate power, insufficient capacity, and poor safety for today’s rapidly growing portable power needs.
Developer of a biopharmaceutical company intended to make biological medicines and other beneficial products. The company develops bioprocesses for the manufacture of biosimilar therapeutic molecules, using high cell density continuous perfusion bioreactors and continuous chromatography or downstream processing techniques, enabling clients to access processes for therapeutic biologicals and viral vaccines.
Stryd, Inc. is a company based in Boulder, Colorado, that specializes in wearable technology for runners. Founded in 2013, it manufactures a foot-mounted power meter designed to enhance running performance by measuring various metrics, including efficiency, technique, and muscle strength. The device utilizes advanced sensing technologies to assess a runner's movement in three-dimensional space while adapting to environmental conditions such as hills and wind. This allows for precise training guidance without relying on GPS, making it suitable for use indoors or outdoors. Stryd's product seamlessly integrates with existing devices and applications, enabling users to monitor their training and refine their performance through personalized insights. The company sells its products online and through retail channels, catering to runners of all levels seeking to improve their training and race outcomes.
Elementum 3D, Inc. is a research and development company based in Erie, Colorado, specializing in additive manufacturing. Founded in 2014, it focuses on the creation of advanced materials, including metals, composites, and ceramics specifically designed for the 3D printing industry. The company produces a variety of products such as aluminum Metal-Matrix Composites, tungsten, copper, nickel and steel Metal-Matrix Composites, nickel titanium, and cemented carbide. These materials are engineered to withstand high loads while providing resistance to abrasion, heat, oxidation, and corrosion. Elementum 3D aims to meet the growing demands of the printing industry by delivering high-quality materials that enhance performance and reliability.
Mallinda LLC, based in Aurora, Colorado, specializes in the development and supply of advanced composite materials. The company has created Pliashell, a platform technology that features intrinsically recyclable and malleable self-healing polymers. These advanced thermoset prepreg laminates allow for the production of lightweight, strong, and remoldable composite materials, significantly enhancing manufacturing efficiency. Pliashell composites can be molded at relatively low temperatures and eliminate the need for a curing step, resulting in reduced manufacturing cycle times. This innovative approach not only streamlines production processes but also supports the circular economy, enabling clients in the automotive and aerospace industries to lower vehicle weight and improve efficiency. Overall, Mallinda is poised to transform product development across various market segments.
MBio Diagnostics, Inc., operating as LightDeck Diagnostics, specializes in developing rapid clinical diagnostics and sample testing products that provide immediate results for various diseases, including HIV, hepatitis, COVID-19, and influenza. The company offers innovative solutions such as the MBio multiplex analyzers and disposable cartridges, which are applicable in medical, veterinary, environmental, food, agricultural, and military sectors. Their flagship product, the LightDeck device, delivers lab-quality results within minutes, making it suitable for diverse settings, from emergency departments and nursing homes to pharmacies and workplaces. Additionally, MBio array systems enable the simultaneous measurement of multiple analytes from a single sample through multiplexed fluorescence immunoassays. Founded in 2009 and headquartered in Boulder, Colorado, MBio Diagnostics is committed to advancing point-of-care testing with its proprietary technology that combines advanced laser waveguides and novel materials.
High Precision Devices, Inc. manufactures, researches, and develops precision instruments. It offers research cryostats for scientific applications, including low-temperature detectors, superconducting devices, and quantum computing; custom cryogenics for low temperature science applications; air sampling systems to collect atmospheric air samples; voltage standard cryo probes and low thermal reversing switches; custom cryo probes and sample holders; quantitative magnetic resonance imaging phantoms; optical mounts; and Heliodon, a sun emulator tool for architects and students. The company also provides research instrument development, balloon and UAV instruments, and outsourced research and development services that include new product development, new product engineering and design, new product design and development, contract precision CNC machining, and product research and development assembly/testing. It serves clients in precision instruments, vacuum and UHV, cryogenics, optics, research physics, aerospace, medical, telecommunications, semi-conductor, science education, and standards and calibration industries; as well as government and university laboratories, and private companies. High Precision Devices, Inc. was incorporated in 1988 and is based in Boulder, Colorado. As of October 19, 2020, High Precision Devices, Inc. operates as a subsidiary of FormFactor, Inc.
Big Blue Technologies specializes in high-temperature thermal processes for upgrading the value of minerals and ores into metals and ceramics. Currently, BBT is developing a thermal magnesium metal production process.
AMP Robotics Corporation specializes in designing and manufacturing robotic systems for material recovery facilities and recycling operations, focusing on automating the identification, sorting, and processing of complex waste streams. The company's flagship product, AMP Cortex, utilizes advanced robotics and computer vision technology to efficiently pick and sort recyclable materials, significantly lowering sorting costs. Additionally, AMP Neuron, a software solution, captures and analyzes material data to identify features in a manner similar to human perception. By leveraging artificial intelligence and machine learning, AMP Robotics enhances recycling processes for various waste types, including municipal solid waste and e-waste. The modular design of its systems allows for easy integration into existing infrastructure, minimizing disruption and capital investment. Founded in 2014 and headquartered in Louisville, Colorado, AMP Robotics has formed strategic partnerships to further its mission of improving recycling rates and economic recovery of recyclables.
DMC Biotechnologies, Inc. is a biotechnology company based in Boulder, Colorado, focused on developing bio-based products through microbial fermentation technology. The company specializes in the production of specialty chemicals, flavors, fragrances, nutraceuticals, and pharmaceuticals. By utilizing Dynamic Metabolic Control technology, DMC aims to streamline the production process, reducing both costs and development timelines from discovery to commercial viability. Founded in 2014, DMC Biotechnologies is dedicated to creating sustainable manufacturing solutions that utilize lower energy and resources, contributing to a more sustainable economy.
LightStanza, a startup located in Boulder, Colorado, specializes in daylight simulation software designed for the construction industry. The company offers a web application that provides a comprehensive analysis of daylighting, which is often overlooked in building design. LightStanza's software utilizes cloud computing to deliver features like point-in-time rendering, illuminance grid animations, and multiple annual analyses, along with tools for LEED scorecards and glare reports. This enables architects, lighting consultants, and sustainable design specialists to generate accurate reports that simulate daylight conditions throughout the year. By focusing specifically on daylighting, LightStanza aims to enhance energy efficiency and improve the overall design of spaces, acknowledging the complexity of light as a dynamic element in architecture.
High Precision Devices, Inc. manufactures, researches, and develops precision instruments. It offers research cryostats for scientific applications, including low-temperature detectors, superconducting devices, and quantum computing; custom cryogenics for low temperature science applications; air sampling systems to collect atmospheric air samples; voltage standard cryo probes and low thermal reversing switches; custom cryo probes and sample holders; quantitative magnetic resonance imaging phantoms; optical mounts; and Heliodon, a sun emulator tool for architects and students. The company also provides research instrument development, balloon and UAV instruments, and outsourced research and development services that include new product development, new product engineering and design, new product design and development, contract precision CNC machining, and product research and development assembly/testing. It serves clients in precision instruments, vacuum and UHV, cryogenics, optics, research physics, aerospace, medical, telecommunications, semi-conductor, science education, and standards and calibration industries; as well as government and university laboratories, and private companies. High Precision Devices, Inc. was incorporated in 1988 and is based in Boulder, Colorado. As of October 19, 2020, High Precision Devices, Inc. operates as a subsidiary of FormFactor, Inc.
Couragion is a company that offers a work-based learning platform aimed at helping students explore and understand career options in science, technology, engineering, and math (STEM). Through its engaging application, Couragion presents videos, games, and self-reflection quizzes that highlight diverse role models in their work environments. This approach not only informs students about various STEM careers but also encourages them to align their interests, values, and desired work characteristics with potential career paths. By fostering STEM career literacy, Couragion supports workforce development and prepares students for future opportunities in these vital fields.
MusiQuest is a music application developed by Edify Technologies, Inc. aimed at helping children explore their passion for music through engaging games and educational content. The application features interactive adventures and animal characters that introduce fundamental musical concepts, guiding kids in the process of composing their own music. MusiQuest provides a platform where young users can learn, improve, and create music in various styles, making the learning experience enjoyable and accessible. Founded in 2015 and based in Denver, Colorado, Edify Technologies, Inc. also offers other music-related applications, including Sketch-a-Song and Opus, which cater to both children and music educators.
Boulder Environmental Sciences and Technology (BEST) is developing several new radiometers for environmental monitoring: a Profiling Radiometer for Atmospheric and Cloud Observation PRACO, a Marine Profiling Radiometer MPR, and an Autonomous Profiling Radiometer. These instruments use novel design approaches that aim to remove the user completely from supervision and allow all-weather operation, data collection, and retrievals. In cooperation with the Atmospheric and Environmental Research (AER) they are working on a design of a Hyperspectral Microwave Sensor.
Air Squared designs and manufactures oil-free scroll compressors, vacuum pumps, and expanders for OEMs. Air Squared, Inc. was founded in 1991 to service the needs of OEMs with oil-free scroll solutions for demanding positive displacement applications. 20 years later, Air Squared is the industry leader in oil-free scroll design and manufacturing, with more experience and more scroll compressor models than any other company.
Double Helix is a team of top talent from a range of fields coming together to advance discovery and research in precision 3D nano-imaging. They have recognized world experts in super-resolution, first-rate engineers in optics, 3D imaging, software, and advisors from the research and business world. They are experts in their fields, collaborators in others, and excited by discovery.
Manufaturer of environmental sampling products intended to simplify the sample collection process. The company's system creates ultrasonic personal air sampler and water sampling products for environment analysis, enabling researchers and industrial hygienists to monitor particulates and pollutants in the work environment and perform fixed measurements within one device.
Developer of a biopharmaceutical company intended to make biological medicines and other beneficial products. The company develops bioprocesses for the manufacture of biosimilar therapeutic molecules, using high cell density continuous perfusion bioreactors and continuous chromatography or downstream processing techniques, enabling clients to access processes for therapeutic biologicals and viral vaccines.
Alef is an app for teaching, learning, and doing math that provides a visceral connection to an equation through touch, and a unique way of communicating abstract concepts on mobile devices.
OptiEnz Sensors, LLC, is a biotech company that produces innovative biosensors for continuously measuring organic chemical concentrations in water and aqueous solutions. The technology is based on fundamental research on enzymatic sensor tips by the company’s founder and CTO, Dr. Ken Reardon. Reardon, a professor and researcher at Colorado State University (CSU), recognized a significant need for a device that could measure the concentration of chemical contaminants in food and water—a device that could take these measurements rapidly, accurately, and inexpensively. Although traditional laboratory sampling methods can yield very accurate measurements, they are also complex, time-intensive, expensive, and—most importantly—they do not provide continuous in-place measurements. Building on his years of research experience in biosensor technology and bioremediation, Reardon decided to combine his knowledge of biosensors and bacterial enzymes to produce a better tool for measuring contaminants in water. In 2010, working in tandem with Colorado State University’s tech transfer, CSU Ventures, Reardon spun-out OptiEnz Sensors, LLC, to develop, manufacture, and sell the biosensors. The company has identified over 50 candidate organic chemicals and has constructed and tested sensor tips for 20 different organic chemicals including alcohols, sugars, hydrocarbons, and solvents. The company is engaged in product trials, as well as sponsored development pilot projects with customers.
Blank Slate Systems, Inc. is a company based in Boulder, Colorado, that specializes in developing design tools and cloud-based collaboration solutions. Founded in 2012, Blank Slate Systems focuses on providing a sketch design tool that integrates with a cloud repository, allowing users to enhance and expedite the creation process. The company's offerings are aimed at design professionals and businesses, facilitating faster prototyping and manufacturing.
Asius Technologies is a Colorado-based company that specializes in the development and marketing of innovative in-ear technology through its product, ADEL (Ambrose Diaphonic Ear Lens). This technology features a polymer bubble that is inserted into the ear canal and inflated to create a comfortable, customizable fit. ADEL enhances sound quality for various audio devices, including hearing aids, headsets, and earbuds, while also minimizing the occlusion effect. The company's focus is on providing users with safe and comfortable audio solutions that can be used over extended periods, ultimately aiming to improve the listening experience while reducing the risk of hearing damage.
Manufaturer of environmental sampling products intended to simplify the sample collection process. The company's system creates ultrasonic personal air sampler and water sampling products for environment analysis, enabling researchers and industrial hygienists to monitor particulates and pollutants in the work environment and perform fixed measurements within one device.
Keystone Tower Systems, Inc. manufactures and installs wind turbine steel towers using spiral welding. It performs all the rolling and welding operations. The company was founded in 2010 and is based in Westminster, Colorado.
Double Helix is a team of top talent from a range of fields coming together to advance discovery and research in precision 3D nano-imaging. They have recognized world experts in super-resolution, first-rate engineers in optics, 3D imaging, software, and advisors from the research and business world. They are experts in their fields, collaborators in others, and excited by discovery.
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