National Science Foundation

The National Science Foundation (NSF), established in 1950 and located in Alexandria, Virginia, is an independent federal agency dedicated to advancing fundamental research and education across all scientific and engineering disciplines. With an annual budget of approximately $7.8 billion, the NSF operates America's Seed Fund, which allocates nearly $200 million each year to support startups and small businesses through the Small Business Innovation Research (SBIR) program. This initiative provides non-dilutive funding of up to $1.5 million to assist in research and development efforts, thereby facilitating the transformation of scientific discoveries into commercially viable products and services. By helping to de-risk technology, the NSF plays a crucial role in fostering innovation and addressing societal challenges through scientific advancements.

James Donlon

Program Director

Sean L. Jones

Assistant Director for Mathematical and Physical Sciences

Sethuraman Panchanathan

Director

Ben Schrag Ph.D

Program Director and Policy Liaison, SBIR / STTR

Past deals in Indiana

CRCL Solutions

Grant in 2021
CRCL Solutions, founded in 2021 and based in South Bend, Indiana, specializes in providing advanced weather forecasting services for wind and solar energy markets, particularly focusing on the Electric Reliability Council of Texas (ERCOT). The company's platform leverages artificial intelligence to enhance forecast accuracy and strengthen the resilience of the power grid. By identifying when existing wind and solar forecasts are inaccurate, CRCL Solutions delivers improved atmospheric forecasting in real-time. This enables power traders to engage in low-risk, high-return trading opportunities while also anticipating market fluctuations, ultimately contributing to more efficient energy management and trading strategies.

Maijker

Grant in 2021
Maijker Corp commercializes groundbreaking AI and sensor technology research. The company uses Industry Standards to develop novel approaches to applying AI to specific manufacturing problems.

Compact Medical

Grant in 2021
Compact Medical Solutions LLC, founded in 2016 and based in Indianapolis, Indiana, specializes in the development of a medical bag-valve-mask (BVM) known as Butterfly BVM. This innovative device is designed to assist medical personnel in ventilating patients experiencing respiratory distress. The Butterfly BVM enhances resuscitation efforts by preventing hyperventilation, ensuring that caregivers can safely and effectively manage patients who are not breathing properly. Through its focus on creating ultra-compact breathing solutions, Compact Medical aims to improve emergency response in critical situations.

Lucata

Grant in 2021
Emu Technology is focused on developing innovative hardware and software solutions that enhance memory utilization and eliminate data bottlenecks in microprocessors. Founded in 2004 and headquartered in South Bend, Indiana, the company has established strategic partnerships with notable firms such as Graham Allen Partners, Aunalytics, Data Realty, and Qumulus Solutions. A key offering from Emu Technology is the next-generation Lucata computer architecture, which significantly accelerates graph analytics, allowing organizations to conduct high-performance, multi-hop analytics on vast databases with up to one trillion vertices. This architecture leverages patented migrating thread technology to scale unified memory and facilitates deeper data analysis using existing graph database software or custom solutions. Emu Technology's solutions are applicable across various sectors, including financial services, cybersecurity, healthcare, telecommunications, and government, thereby enabling organizations to harness the power of advanced analytics and machine learning.

MITS

Grant in 2021
MITS develops multiscale integrated technology solutions to improve mechanical, thermal, and electrical performance. The company was founded in 2019 and is headquartered in Carmel, Indiana.

South Bend Woodworks

Grant in 2021
South Bend Woodworks, established in 2013 and based in South Bend, Indiana, specializes in creating handcrafted wooden toys and furniture tailored for small children. The company offers a diverse product catalog that includes personalized name puzzles, memorabilia, blocks, cutting boards, and various play accessories. South Bend Woodworks focuses on providing engaging and enjoyable play experiences for children through its high-quality, handcrafted items.

Eradivir

Grant in 2021
Eradivir is a biotech company established in 2020 and based in West Lafayette, Indiana. The company focuses on developing a novel bispecific immunotherapy platform aimed at combating the virus responsible for COVID-19. Eradivir's approach involves creating non-immunological targeting agents that possess high specificity and avidity for a unique domain of the spike protein found on various coronaviruses. This innovation enables the effective elimination of both free viruses and virus-infected cells, even during advanced stages of infection, thereby empowering patients' immune systems to address viral challenges more efficiently.
Akanocure's mission is to synthesize and develop biotargeted anti-cancer chemotherapeutic drugs derived from natural sources. Akanocure's pipeline will consist of analogs of fully validated, highly potent anti-cancer natural products that can only be produced on a large scale through Akanocure's proprietary CCC synthesis platform. The company has competitive edges on two fronts: the synthesis platform that gives Akanocure exclusive access to rare compounds and the potential pipeline of anti-cancer products that are far superior to existing therapies.

ChameleonCloud

Grant in 2020
Cloud services have become ubiquitous to all major 21st century economic activities. However, cloud services and technologies can be significantly more powerful than they are now. A persistent barrier to further advancement has been the lack of a large-scale and open cloud research platforms. With funding from the National Science Foundation (NSF), the Chameleon project will provide such a large-scale platform to the open research community allowing them explore transformative concepts in deeply programmable cloud services, design, and core technologies. Chameleon will allow users to explore problems ranging from the creation of Software as a Service to kernel support for virtualization. This broad range of supported research includes many other areas such as developing Platforms as a Service, creating new and optimizing existing Infrastructure as a Service components, investigating software-defined networking, and optimizing virtualization technologies. The Chameleon testbed, will be deployed at the University of Chicago and the Texas Advanced Computing Center and will consist of 650 multi-core cloud nodes, 5PB of total disk space, and leverage 100 Gbps connection between the sites. While a large part of the testbed will consist of homogenous hardware to support large-scale experiments, a portion of it will support heterogeneous units allowing experimentation with high-memory, large-disk, low-power, GPU, and co-processor units. The project will also leverage existing FutureGrid hardware at the University of Chicago and the Texas Advanced Computing Center in its first year to provide a transition period for the existing FutureGrid community of experimental users. To support the broad range of experiments experiments described above, the project will support a graduated configuration system allowing full user configurability of the software stack, from provisioning of bare metal and network interconnects to delivery of fully functioning cloud environments. A special feature of Chameleon is that it provides for an exceptionally close integration of clouds and networks, which substantially enhances the capabilities of both. In addition, to facilitate experiments, Chameleon will support a set of services designed to meet researchers needs, including support for experimental management, reproducibility, and repositories of trace and workload data of production cloud workloads. The project is led by the Computation Institute at the University of Chicago and partners from the Texas Advanced Computing Center at the University of Texas at Austin, the International Center for Advanced Internet Research at Northwestern University, the Ohio State University, and University of Texas at San Antonio, comprising a highly qualified and experienced team. The team includes members from the NSF supported FutureGrid project and from the GENI community, both forerunners of the NSFCloud solicitation under which this project is funded. Chameleon will also form a set of partnerships with commercial and academic clouds, such as Rackspace, CERN and Open Science Data Cloud (OSDC), and will partner with other testbeds, notably GENI and INRIA's Grid'5000 testbed.

Terran Robotics

Grant in 2020
Terran Robotics is a construction company that specializes in AI and robotics. The company's headquarters are in Bloomington, Indiana.

MIFtek

Grant in 2020
MIFtek is a company based in West Lafayette, Indiana, established in 2013, that specializes in developing advanced cellular analysis platforms. These platforms are designed to extract complex information from cells using innovative detectors and illumination processes. By employing new parameters and methods, MIFtek enables research organizations to gain insights into cellular systems and their functions, facilitating a deeper understanding of biological processes.

RightFit Analytics

Grant in 2020
RightFit Analytics develops a precision health-focused analytics platform that learns success patterns associated with medical operations. The company was founded in 2018 and is based in West Lafayette, Indiana.
Akanocure's mission is to synthesize and develop biotargeted anti-cancer chemotherapeutic drugs derived from natural sources. Akanocure's pipeline will consist of analogs of fully validated, highly potent anti-cancer natural products that can only be produced on a large scale through Akanocure's proprietary CCC synthesis platform. The company has competitive edges on two fronts: the synthesis platform that gives Akanocure exclusive access to rare compounds and the potential pipeline of anti-cancer products that are far superior to existing therapies.

Valgotech

Grant in 2020
Valgotech specializes in advanced materials, energy storage, and renewable energy systems. The company was established in 2018 and is based in Fishers, Indiana.

Biomineral Systems

Grant in 2020
Provider of environmental biochemical research, education, and technology-related services intended to address global environmental challenges. The company's services include phosphorus management, management of soil organic carbon and enhancing soil quality, biogeochemical modeling for forest management, carbon trading and capture, mineral synthesis and characterization, and acid mine drainage, enabling scientists and engineers to address challenges related to food security, environmental sustainability, and biodiversity.

Purdue University

Grant in 2019
Purdue University, established in 1869 and located in West Lafayette, Indiana, is a non-profit educational institution renowned for its diverse academic offerings, including undergraduate and graduate programs in fields such as agriculture, engineering, health sciences, and liberal arts. The university enhances its educational mission through a significant endowment, which is supported by contributions from alumni and friends, providing a stable funding source for scholarships, professorships, and research initiatives. In addition to its main campus, Purdue also offers learning programs at various locations across Indiana through the College of Technology. The management of the university's assets is overseen by an executive management team, ensuring effective governance and strategic growth in its academic and financial endeavors.

Bee Corp.

Grant in 2019
Bee Corp. is a company that focuses on developing data analytics and decision-support solutions for beekeeping. Its primary products include Queen's Guard, a tool for monitoring and managing bee queens, which utilizes a beehive sensor and data analytics software to track hive conditions. The system monitors temperature and other critical data, sending alerts to users when it detects potential queen loss. Additionally, Bee Corp. offers Verifli, which employs infrared inspection technology to assess bee health and distribution, ensuring effective pollination for growers. By providing these advanced monitoring solutions, Bee Corp. aims to support beekeepers and contribute to the sustainable restoration of honeybee populations. Founded in 2016, the company is headquartered in Indianapolis, Indiana.

Nutramaize

Grant in 2019
NutraMaize is an Indiana based AgBioScience company commercializing a more nutritious, better tasting, variety of non-GMO corn. NutraMaize's proprietary corn variety possesses a deep orange color, which is produced by its high carotenoid content. Carotenoids are a family of nutrients with a number of critical functions in the human body including serving as anti-oxidants, anti-inflammatory agents, and providing pro-vitamin A.

NutraMaize

Grant in 2019
NutraMaize LLC has developed and is attempting to broadly commercialize orange-colored corn which contains higher levels of carotenoids

Purdue University

Grant in 2019
Purdue University, established in 1869 and located in West Lafayette, Indiana, is a non-profit educational institution renowned for its diverse academic offerings, including undergraduate and graduate programs in fields such as agriculture, engineering, health sciences, and liberal arts. The university enhances its educational mission through a significant endowment, which is supported by contributions from alumni and friends, providing a stable funding source for scholarships, professorships, and research initiatives. In addition to its main campus, Purdue also offers learning programs at various locations across Indiana through the College of Technology. The management of the university's assets is overseen by an executive management team, ensuring effective governance and strategic growth in its academic and financial endeavors.

Explore Interactive

Grant in 2019
At Explore Interactive we democratize access to and improve educational outcomes in STEM, through immersive, educational games anywhere, anytime and at a great price. Their first product, coming soon, will bring together the delight of tabletop card games and the immersion of our augmented reality technology to build excitement for and expertise in the world of STEM. Explore! brings inquiry-based learning to the world of augmented reality through educational games. Their experiences engage Explorers through a visual, auditory and tactile learning environment to progress through standards-based curricula. Whether a tinkerer, competitor, or social player, Explore! has something for everyone!

Vibronix

Grant in 2019
Vibronix, Inc. develops healthcare equipment for diagnosis and treatment of cancer. It offers LipoPAT, a multi-modal intraoperative imaging tool based on ultrasound and photoacoustic tomography; and AcouStar, an optoacoustic fiber guide with augmented reality for tumor localization and device tracking. The company also provides IVPA, an intravascular photoacoustic catheter system for atherosclerosis disease characterization that is used to guide treatment procedures, customize treatment, and assess efficacy of therapeutics in clinical trial. The company was incorporated in 2013 and is based in West Lafayette, Indiana with an additional office in Suzhou, China.

Cloudseal

Grant in 2019
Hard-to-reproduce bugs waste developers’ time. Cloudseal’s goal is to make computing reliable and predictable, with all bugs instantly and accurately reproducible. To that end, Cloudseal’s secure deterministic container technology enables efficient, always-on recording of software behavior.
PC Krause and Associates (PCKA) was incorporated in the state of Indiana in 1983. After the successful completion of several small task-ordered contracts with government agencies and Midwest utilities, PCKA was starting to become recognized as an up-and-coming consulting company with highly-talented engineers. It is a high-tech company with a concentration of high-level expertise in the dynamics of electromechanical systems with particular emphasis on power-electronic-based systems of the types to be found in advanced aircraft, ships, and ground vehicles. The company has a well-established reputation for solving engineering challenges through the use of advanced modeling, simulation, analysis, and control techniques.
Akanocure's mission is to synthesize and develop biotargeted anti-cancer chemotherapeutic drugs derived from natural sources. Akanocure's pipeline will consist of analogs of fully validated, highly potent anti-cancer natural products that can only be produced on a large scale through Akanocure's proprietary CCC synthesis platform. The company has competitive edges on two fronts: the synthesis platform that gives Akanocure exclusive access to rare compounds and the potential pipeline of anti-cancer products that are far superior to existing therapies.

Bee Corp.

Grant in 2017
Bee Corp. is a company that focuses on developing data analytics and decision-support solutions for beekeeping. Its primary products include Queen's Guard, a tool for monitoring and managing bee queens, which utilizes a beehive sensor and data analytics software to track hive conditions. The system monitors temperature and other critical data, sending alerts to users when it detects potential queen loss. Additionally, Bee Corp. offers Verifli, which employs infrared inspection technology to assess bee health and distribution, ensuring effective pollination for growers. By providing these advanced monitoring solutions, Bee Corp. aims to support beekeepers and contribute to the sustainable restoration of honeybee populations. Founded in 2016, the company is headquartered in Indianapolis, Indiana.

Perceive

Grant in 2017
Perceive Inc specializes in developing advanced camera software that provides spatial analytics for various physical environments, including retail stores, museums, and libraries. Founded in 2015 and based in Fishers, Indiana, the company utilizes artificial intelligence and computer vision to capture and analyze 3D video data on consumer interactions within these spaces. By integrating sensors into existing lighting wiring, Perceive creates detailed 3D maps without relying on face recognition or traditional tracking methods, enabling businesses to optimize employee performance and enhance customer experiences. This technology allows organizations to make data-driven decisions rather than relying on anecdotal evidence, significantly improving the efficiency of data collection in physical environments.

VinSense

Grant in 2017
VinSense is an Indiana LLC formed in March 2015 to produce an innovative decision support software system for agricultural crop production. The new technology enables producers, field managers, and winemakers to make better crop management decisions to improve production volume, uniformity and quality and increase profitability and long-term sustainability. The VinSense software, initially targeted at the wine grape growing and winemaking industry, will deliver the following value to our customers: Increased crop volume Enhanced crop uniformity Better crop management – cover crop decisions, irrigation practices, pruning, canopy management, and other crop management decisions Long-term crop sustainability Better soil moisture management – resulting in water conservation and lower irrigation costs Optimal soil nutrient management Better environmental protection practices Our product is based on the latest soil, viticulture, enology, and predictive analytics research, as well as the latest sensing technologies (in situ and remotely sensed). The key unique components of the system are the transformation of this data deluge into easily understood information relevant to crop and winemaking decisions and the incorporation of soil physics and hydrology, viticulture, and enological models to increase the relevance of the information and enable predictive analytics for management and planning. The user-friendly visual interface and decision tools are being developed with “real world” producers to ensure that the data provided is relevant, understandable, and, most importantly, actionable.

Perceive

Grant in 2017
Perceive Inc specializes in developing advanced camera software that provides spatial analytics for various physical environments, including retail stores, museums, and libraries. Founded in 2015 and based in Fishers, Indiana, the company utilizes artificial intelligence and computer vision to capture and analyze 3D video data on consumer interactions within these spaces. By integrating sensors into existing lighting wiring, Perceive creates detailed 3D maps without relying on face recognition or traditional tracking methods, enabling businesses to optimize employee performance and enhance customer experiences. This technology allows organizations to make data-driven decisions rather than relying on anecdotal evidence, significantly improving the efficiency of data collection in physical environments.

ZeroUI

Grant in 2017
ZeroUI Inc. is an innovative technology company based in West Lafayette, Indiana, founded in 2012. It specializes in hands-free and gesture-based 3D modeling technology, allowing users to create and interact with 3D shapes through hand gestures. The company offers a variety of applications across virtual reality, augmented reality, robotics, the Internet of Things, and wearables. One of its notable products is HandiMate, a robotic toy construction kit designed for children that promotes STEM learning, playful communication, and storytelling. Additionally, ZeroUI provides an e-learning platform that facilitates immersive experiential learning, making it accessible anytime and anywhere through its IoT Robotics system. This platform encourages users to explore and utilize a collective knowledge base from community projects, fostering creativity and innovation.

Biomineral Systems

Grant in 2017
Provider of environmental biochemical research, education, and technology-related services intended to address global environmental challenges. The company's services include phosphorus management, management of soil organic carbon and enhancing soil quality, biogeochemical modeling for forest management, carbon trading and capture, mineral synthesis and characterization, and acid mine drainage, enabling scientists and engineers to address challenges related to food security, environmental sustainability, and biodiversity.

Nutramaize

Grant in 2017
NutraMaize is an Indiana based AgBioScience company commercializing a more nutritious, better tasting, variety of non-GMO corn. NutraMaize's proprietary corn variety possesses a deep orange color, which is produced by its high carotenoid content. Carotenoids are a family of nutrients with a number of critical functions in the human body including serving as anti-oxidants, anti-inflammatory agents, and providing pro-vitamin A.

Pinpoint Pharma

Grant in 2017
Pinpoint Pharma, a healthcare company, is changing veterinary medicine by printing custom medicine for pets on demand.
Sintact Medical Systems, founded in 2013 and based in Bloomington, Indiana, specializes in the development of non-resorbable films designed to prevent surgical adhesions. These films serve as a barrier that separates adjacent organs and tissues during the healing process, significantly reducing the risk of internal scar formation and associated postoperative complications. By preventing tissue attachment, Sintact's products not only enhance patient outcomes but also facilitate clearer visibility for clinicians in the event of reoperation.
Developer of biomass conversion and hydrogen storage technology designed to study the storage of hydrogen on a novel material produced from silicon. The company's technology has the potential to eclipse all prior methods of hydrogen storage in terms of pressure, temperature, safety, cost, and convenience and converts biomass into energy, chemicals, fuel, and heat, enabling clients to access their technology to store biogas in porous silicon, smaller, lighter, and safer than battery storage.

Vibronix

Grant in 2016
Vibronix, Inc. develops healthcare equipment for diagnosis and treatment of cancer. It offers LipoPAT, a multi-modal intraoperative imaging tool based on ultrasound and photoacoustic tomography; and AcouStar, an optoacoustic fiber guide with augmented reality for tumor localization and device tracking. The company also provides IVPA, an intravascular photoacoustic catheter system for atherosclerosis disease characterization that is used to guide treatment procedures, customize treatment, and assess efficacy of therapeutics in clinical trial. The company was incorporated in 2013 and is based in West Lafayette, Indiana with an additional office in Suzhou, China.

Spero Energy

Grant in 2016
Spero Energy, Inc. is an Indiana based company with the mission of developing cost competitive processes for the conversion of abundant non-food biomass to high value chemicals (HVCs) and renewable fuels. With its experienced and outstanding research and business team, Spero Energy has developed processes for a range of renewable chemicals targeting the flavor, fragrance, and pharmaceutical industries. Our initial lignin-derived flavor and fragrance chemicals target a multi-billion dollar market segment.
PC Krause and Associates (PCKA) was incorporated in the state of Indiana in 1983. After the successful completion of several small task-ordered contracts with government agencies and Midwest utilities, PCKA was starting to become recognized as an up-and-coming consulting company with highly-talented engineers. It is a high-tech company with a concentration of high-level expertise in the dynamics of electromechanical systems with particular emphasis on power-electronic-based systems of the types to be found in advanced aircraft, ships, and ground vehicles. The company has a well-established reputation for solving engineering challenges through the use of advanced modeling, simulation, analysis, and control techniques.

Purdue University

Grant in 2016
Purdue University, established in 1869 and located in West Lafayette, Indiana, is a non-profit educational institution renowned for its diverse academic offerings, including undergraduate and graduate programs in fields such as agriculture, engineering, health sciences, and liberal arts. The university enhances its educational mission through a significant endowment, which is supported by contributions from alumni and friends, providing a stable funding source for scholarships, professorships, and research initiatives. In addition to its main campus, Purdue also offers learning programs at various locations across Indiana through the College of Technology. The management of the university's assets is overseen by an executive management team, ensuring effective governance and strategic growth in its academic and financial endeavors.

Perceive

Grant in 2016
Perceive Inc specializes in developing advanced camera software that provides spatial analytics for various physical environments, including retail stores, museums, and libraries. Founded in 2015 and based in Fishers, Indiana, the company utilizes artificial intelligence and computer vision to capture and analyze 3D video data on consumer interactions within these spaces. By integrating sensors into existing lighting wiring, Perceive creates detailed 3D maps without relying on face recognition or traditional tracking methods, enabling businesses to optimize employee performance and enhance customer experiences. This technology allows organizations to make data-driven decisions rather than relying on anecdotal evidence, significantly improving the efficiency of data collection in physical environments.

VinSense

Grant in 2016
VinSense is an Indiana LLC formed in March 2015 to produce an innovative decision support software system for agricultural crop production. The new technology enables producers, field managers, and winemakers to make better crop management decisions to improve production volume, uniformity and quality and increase profitability and long-term sustainability. The VinSense software, initially targeted at the wine grape growing and winemaking industry, will deliver the following value to our customers: Increased crop volume Enhanced crop uniformity Better crop management – cover crop decisions, irrigation practices, pruning, canopy management, and other crop management decisions Long-term crop sustainability Better soil moisture management – resulting in water conservation and lower irrigation costs Optimal soil nutrient management Better environmental protection practices Our product is based on the latest soil, viticulture, enology, and predictive analytics research, as well as the latest sensing technologies (in situ and remotely sensed). The key unique components of the system are the transformation of this data deluge into easily understood information relevant to crop and winemaking decisions and the incorporation of soil physics and hydrology, viticulture, and enological models to increase the relevance of the information and enable predictive analytics for management and planning. The user-friendly visual interface and decision tools are being developed with “real world” producers to ensure that the data provided is relevant, understandable, and, most importantly, actionable.

Phytoption

Grant in 2016
Phytoption LLC, founded in 2011 and based in West Lafayette, Indiana, specializes in developing phytoglycogen-based biopolymers and natural-derived materials. The company focuses on creating sustainable ingredients that enhance human health and address solubility challenges in various applications. Its product offerings include proprietary non-GMO biomaterials and ingredients tailored for the pharmaceutical, agriculture, cosmetics, and food and beverage industries. By improving product shelf life, sensory properties, bioavailability, functionality, and nutritional values, Phytoption aims to provide valuable solutions that benefit its clients across multiple sectors.

ZeroUI

Grant in 2015
ZeroUI Inc. is an innovative technology company based in West Lafayette, Indiana, founded in 2012. It specializes in hands-free and gesture-based 3D modeling technology, allowing users to create and interact with 3D shapes through hand gestures. The company offers a variety of applications across virtual reality, augmented reality, robotics, the Internet of Things, and wearables. One of its notable products is HandiMate, a robotic toy construction kit designed for children that promotes STEM learning, playful communication, and storytelling. Additionally, ZeroUI provides an e-learning platform that facilitates immersive experiential learning, making it accessible anytime and anywhere through its IoT Robotics system. This platform encourages users to explore and utilize a collective knowledge base from community projects, fostering creativity and innovation.

Mobile Enerlytics

Grant in 2015
Mobile Enerlytics, LLC, founded in 2014 and based in West Lafayette, Indiana, specializes in technologies aimed at extending smartphone battery life through innovative mobile application design. The company offers Estar, an Android application that helps users identify and uninstall energy-inefficient apps, thereby enhancing battery longevity. Additionally, Mobile Enerlytics provides Eprof, an energy analysis and diagnostic tool that assists application developers in identifying sources of excessive battery drain within their code. This tool enables creators to optimize their applications, minimize user frustration due to low battery life, and improve competitive positioning in the market. By addressing energy management effectively, Mobile Enerlytics contributes to increased user engagement and revenue for both app vendors and handset manufacturers.

SensorHound

Grant in 2015
SensorHound Innovations LLC, founded in 2012 and based in West Lafayette, Indiana, specializes in Internet of Things (IoT) software products and services aimed at minimizing development and operational costs. The company has developed a proactive and automated operations monitoring platform that addresses the critical issues of reliability and security in IoT applications. By providing continuous monitoring, the platform detects failures, security vulnerabilities, and performance issues in real time, delivering immediate alerts and detailed diagnostic information to facilitate rapid root cause analysis. This innovative solution, built on over a decade of research by leading IoT experts, significantly enhances the efficiency of monitoring operations, ultimately reducing maintenance costs associated with IoT deployments.

Animated Dynamics

Grant in 2015
Animated Dynamics, Inc. specializes in the development and commercialization of live-tissue imaging technologies aimed at enhancing drug assessment and analysis in the life and health sciences. The company's core offering, Biodynamic Imaging, utilizes low-coherence digital holography to capture and analyze cellular motions within living tissue, providing insights that are more physiologically relevant than traditional two-dimensional methods. This label-free technique enables the examination of drug responses in three-dimensional tissue environments, facilitating a comprehensive understanding of cellular mechanisms of action. Animated Dynamics also supplies advanced microscopy solutions to support its imaging platform. Founded in 2011 and based in West Lafayette, Indiana, the company focuses on transforming drug evaluation through innovative imaging capabilities.

LC Drives

Grant in 2015
LC Drives, Inc., doing business as LC Drives, develops, manufactures, markets, and sells light-weight motors and generators for marine propulsion, wind, and industrial process automation. It offers power-dense, liquid-cooled permanent magnet electrical machines. The company was founded in 2012 and is based in Potsdam, New York.

ZeroUI

Grant in 2015
ZeroUI Inc. is an innovative technology company based in West Lafayette, Indiana, founded in 2012. It specializes in hands-free and gesture-based 3D modeling technology, allowing users to create and interact with 3D shapes through hand gestures. The company offers a variety of applications across virtual reality, augmented reality, robotics, the Internet of Things, and wearables. One of its notable products is HandiMate, a robotic toy construction kit designed for children that promotes STEM learning, playful communication, and storytelling. Additionally, ZeroUI provides an e-learning platform that facilitates immersive experiential learning, making it accessible anytime and anywhere through its IoT Robotics system. This platform encourages users to explore and utilize a collective knowledge base from community projects, fostering creativity and innovation.

AccuPS

Grant in 2014
AccuPS, LLC, established in 2014 and based in West Lafayette, Indiana, specializes in high-definition 3D motion tracking technology. The company offers innovative products such as AeroWand, which turns smartphones and TVs into virtual reality entertainment systems, and AeroDynaPen, a versatile 3D stylus compatible with various devices including phones, tablets, and computers. AccuPS has developed a mobile virtual reality system that incorporates a head-tracking device, hand controller, and transmitting antenna, all of which connect to smartphones to facilitate precise motion tracking for virtual and augmented reality experiences.

Animated Dynamics

Grant in 2014
Animated Dynamics, Inc. specializes in the development and commercialization of live-tissue imaging technologies aimed at enhancing drug assessment and analysis in the life and health sciences. The company's core offering, Biodynamic Imaging, utilizes low-coherence digital holography to capture and analyze cellular motions within living tissue, providing insights that are more physiologically relevant than traditional two-dimensional methods. This label-free technique enables the examination of drug responses in three-dimensional tissue environments, facilitating a comprehensive understanding of cellular mechanisms of action. Animated Dynamics also supplies advanced microscopy solutions to support its imaging platform. Founded in 2011 and based in West Lafayette, Indiana, the company focuses on transforming drug evaluation through innovative imaging capabilities.

Spero Energy

Grant in 2014
Spero Energy, Inc. is an Indiana based company with the mission of developing cost competitive processes for the conversion of abundant non-food biomass to high value chemicals (HVCs) and renewable fuels. With its experienced and outstanding research and business team, Spero Energy has developed processes for a range of renewable chemicals targeting the flavor, fragrance, and pharmaceutical industries. Our initial lignin-derived flavor and fragrance chemicals target a multi-billion dollar market segment.

WisdomTools

Grant in 2014
Viyant is an integrated suite of technology that enables mobile communication and collaboration by providing a combination of hardware, mixed reality software tools and support services that are optimized for facilitating work at a distance. By leveraging the company's team's extensive expertise with mixed/augmented reality software development, wireless communication, networking and industry expertise, Information in Place will develop Viyant to evolve with the market and to be the lead provider of mobile mixed reality products and services across a range of industries and operating environments.
Nano-Meta Technologies develops and commercializes intellectual property. The company offers nano-antennas for heat-assisted magnetic data recording, ultra-thin optical elements, meta-surfaces, and chemical/bio/medical sensing and probing applications. It was founded in 2010 and headquartered in West Lafayette, Indiana.

Purdue Research Park

Grant in 2013
Purdue Research Park is dedicated to fostering innovation and economic development in alignment with Purdue University's strategic goals. The Purdue Research Foundation, which manages the park, focuses on advancing discovery and learning through effective stewardship of resources. It supports technology transfer, oversees intellectual property management, and engages in real estate and financial asset development. The park provides valuable business incubation services and networking opportunities, including events such as "Party in the Park," seminars, and entrepreneurship academies. Additionally, it distributes an e-newsletter, Innovation Express, to keep stakeholders informed about developments and milestones within the park. Tenants benefit from a range of low-cost or complimentary services designed to enhance their business prospects.

SensorHound

Grant in 2013
SensorHound Innovations LLC, founded in 2012 and based in West Lafayette, Indiana, specializes in Internet of Things (IoT) software products and services aimed at minimizing development and operational costs. The company has developed a proactive and automated operations monitoring platform that addresses the critical issues of reliability and security in IoT applications. By providing continuous monitoring, the platform detects failures, security vulnerabilities, and performance issues in real time, delivering immediate alerts and detailed diagnostic information to facilitate rapid root cause analysis. This innovative solution, built on over a decade of research by leading IoT experts, significantly enhances the efficiency of monitoring operations, ultimately reducing maintenance costs associated with IoT deployments.

Phytoption

Grant in 2013
Phytoption LLC, founded in 2011 and based in West Lafayette, Indiana, specializes in developing phytoglycogen-based biopolymers and natural-derived materials. The company focuses on creating sustainable ingredients that enhance human health and address solubility challenges in various applications. Its product offerings include proprietary non-GMO biomaterials and ingredients tailored for the pharmaceutical, agriculture, cosmetics, and food and beverage industries. By improving product shelf life, sensory properties, bioavailability, functionality, and nutritional values, Phytoption aims to provide valuable solutions that benefit its clients across multiple sectors.

En'urga

Grant in 2013
Developer of customized optical diagnostic equipment designed to serve in factory floor applications. The company specializes in research, design, prototype development, customization, and calibration of optical diagnostic equipment, enabling businesses and clients to get quality measurements and control varied processes in a wide array of industries.

Spensa

Grant in 2013
Spensa Technologies Inc. is an agricultural software solutions provider based in West Lafayette, Indiana, founded in 2009 by Johnny Park. The company develops innovative tools designed to enhance crop production efficiency and reduce reliance on manual labor. Among its offerings are OpenScout, a scouting application for recording field observations, and MyTraps, a mobile tool for collecting and visualizing pest data. Additionally, Spensa provides Z-Trap, a smart insect trap system that helps farmers analyze and predict insect populations. With a focus on eco-friendly farming practices, Spensa leverages advanced technologies in wireless sensor networks, robotics, and computer vision to support the agricultural industry. As of 2018, Spensa operates as a subsidiary of Telvent DTN, LLC.
Tymora Analytical Operations, LLC specializes in providing tools for phosphorylation analysis aimed at research and development organizations within the life sciences sector. Founded in 2010 and based in West Lafayette, Indiana, the company has developed innovative nanotechnologies to analyze protein phosphorylation, which is linked to various diseases, including cancer. Its primary products include pIMAGO, a non-antibody solution for unbiased detection of phosphoproteins, and PolyMAC, designed for the isolation of phosphopeptides. Tymora serves its customers through a network of distributors in the United States and internationally, as well as through online channels. The company has also established a strategic alliance with Veravas, Inc., further enhancing its position in the field of proteomics and drug development.

Medtric Biotech

Grant in 2012
Medtric Biotech, LLC develops and commercializes antibiotic-free germicidal solutions for the medical field, as well as consumer, industrial, and agricultural applications. Its solutions are based on water-based nano-emulsion technology that utilizes plant derived compounds as antimicrobial agents. The company offers wound care and sanitizing products that hand sanitizers and skin antiseptics; antimicrobial solutions for the living room and the clean room; and sanitizers to prolong shelf-life and increase consumer health. Medtric Biotech, LLC was founded in 2010 and is based in Lafayette, Indiana.

SmarterShade

Grant in 2012
Imagine - being able to electronically darken a window with the flip of a switch.SmarterShade is an emerging clean technology that does just this. Windows, skylights and other glazings made with SmarterShade can be darkened on command. As part of a daylighting/natural heating strategy, this technology has the potential to save the United States billions in energy costs. SmarterShade is a concept from Lono, LLC, a company based in South Bend, Indiana. Through their own proprietary technology, they have developed an aftermarket application for selectable tint on windows that:
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