National Science Foundation

Glossifi is a developer of web3 blockchain software focused on Ethereum trading. The company creates blockchain analytics tools that facilitate digital money transactions, global payments, and various applications. Through its innovations, Glossifi aims to enable users to efficiently trade and invest in Ethereum, enhancing the overall experience in the blockchain ecosystem.

InsectaPel specializes in biobased insect repellent products designed for textiles, focusing on providing effective solutions to prevent blood-sucking insects from biting humans. The company’s innovative extended-release technology enhances the functionality of fabrics, ensuring long-lasting protection while adhering to regulatory standards. By offering sustainable and cost-effective alternatives, InsectaPel aims to transform the market for insect repellents, addressing both consumer needs and public health concerns related to insect-borne diseases.

SpheroFill is a drug delivery platform that specializes in the development of injectable tissue fillers, particularly for treating age-related atrophy in the larynx. The company utilizes a unique combination of solid, hollow, and porous-wall hollow glass microspheres mixed with biocompatible and bioactive matrices. This innovative approach enhances the delivery of active pharmaceutical ingredients (APIs) in various forms, including solids, liquids, and gases. By improving compliance through reduced dosing frequency and enabling previously impossible oral formulations, SpheroFill is positioned as a leader in advancing drug delivery technology, offering healthcare professionals enhanced devices for more effective treatments.

DPX Technologies, founded in 2007 and based in Columbia, South Carolina, specializes in patented pipette tip technology aimed at enhancing the quality of products used in complex chemical and biological analyses. The company's innovative technology is designed for automated liquid handling systems, offering customizable solutions that simplify and automate intricate sample preparation processes. This enables scientists to efficiently implement automated solutions that can be tailored to various laboratory workflows and methods, thereby improving overall analytical performance in research and development settings.

GeoMat is a nanotechnology company headquartered in Columbia, South Carolina, that specializes in oil remediation. Founded in 2014, the company has developed a technology that utilizes nanoparticles and magnets to effectively separate oil from water mixtures. This innovative platform enables the removal of oil from both soil and water, allowing industries to clean major water bodies and natural resources. GeoMat's solutions aim to ensure the availability of drinkable and decontaminated water while also addressing the challenges posed by oil spills.

Cloud services have become ubiquitous to all major 21st century economic activities. However, cloud services and technologies can be significantly more powerful than they are now. A persistent barrier to further advancement has been the lack of a large-scale and open cloud research platforms. With funding from the National Science Foundation (NSF), the Chameleon project will provide such a large-scale platform to the open research community allowing them explore transformative concepts in deeply programmable cloud services, design, and core technologies. Chameleon will allow users to explore problems ranging from the creation of Software as a Service to kernel support for virtualization. This broad range of supported research includes many other areas such as developing Platforms as a Service, creating new and optimizing existing Infrastructure as a Service components, investigating software-defined networking, and optimizing virtualization technologies. The Chameleon testbed, will be deployed at the University of Chicago and the Texas Advanced Computing Center and will consist of 650 multi-core cloud nodes, 5PB of total disk space, and leverage 100 Gbps connection between the sites. While a large part of the testbed will consist of homogenous hardware to support large-scale experiments, a portion of it will support heterogeneous units allowing experimentation with high-memory, large-disk, low-power, GPU, and co-processor units. The project will also leverage existing FutureGrid hardware at the University of Chicago and the Texas Advanced Computing Center in its first year to provide a transition period for the existing FutureGrid community of experimental users. To support the broad range of experiments experiments described above, the project will support a graduated configuration system allowing full user configurability of the software stack, from provisioning of bare metal and network interconnects to delivery of fully functioning cloud environments. A special feature of Chameleon is that it provides for an exceptionally close integration of clouds and networks, which substantially enhances the capabilities of both. In addition, to facilitate experiments, Chameleon will support a set of services designed to meet researchers needs, including support for experimental management, reproducibility, and repositories of trace and workload data of production cloud workloads. The project is led by the Computation Institute at the University of Chicago and partners from the Texas Advanced Computing Center at the University of Texas at Austin, the International Center for Advanced Internet Research at Northwestern University, the Ohio State University, and University of Texas at San Antonio, comprising a highly qualified and experienced team. The team includes members from the NSF supported FutureGrid project and from the GENI community, both forerunners of the NSFCloud solicitation under which this project is funded. Chameleon will also form a set of partnerships with commercial and academic clouds, such as Rackspace, CERN and Open Science Data Cloud (OSDC), and will partner with other testbeds, notably GENI and INRIA's Grid'5000 testbed.

Obsidio, Inc. develops shear-thinning hydrogel biomaterial technology and manufactures therapeutic devices and universal gel embolization material using that technology. The company’s embolic material, injectable through catheters in a minimally invasive way, helps to stop undesired blood flow through vessels anywhere in the body. Its technology can be used in the treatment of hemorrhage, aneurysm, and cancer. The company was founded in 2018 and is based in Solana Beach, California.

Clemson University is a prominent land-grant institution located in South Carolina, known for its commitment to research that benefits the community. It is the second-largest university in the state by student enrollment, offering a vibrant campus life with over 400 student clubs and organizations. The university emphasizes both academic and extracurricular engagement, particularly through its NCAA Division I athletic program, represented by the Clemson Tigers. The Clemson Venture Accelerator supports students, faculty, and staff in entrepreneurial endeavors, offering resources such as workshops, incubator workspace, and mentoring to help develop business ideas. Founded in 1933, the Clemson University Foundation enhances academic and research initiatives, public service, and student experiences, further solidifying the university's role in fostering educational excellence and community improvement.

Tetramer Technologies is a research company offering polymer design and synthesis services.

Tetramer Technologies is a research company offering polymer design and synthesis services.

ZillionInfo provides location intelligence solutions to help clients deal with large datasets, dig into data insights, and make better location allocation decisions such as site selection, territory mapping, and routing.

Cirtemo specializes in the development of advanced optical filter technology aimed at enhancing chemical detection capabilities. The company's innovative multivariate optical elements utilize microscopic sensors to provide increased sensitivity and specificity in analyte detection, surpassing the limitations of traditional narrow band pass filters. By partnering with Optical Filter Manufacturers and Optical Component and System Manufacturers, Cirtemo enables these partners to offer differentiated products while maintaining a strong intellectual property position. This collaboration empowers clients to address new applications in chemical measurement that were previously unattainable, ultimately improving detection limits and minimizing crosstalk in their analytical processes.

The Center for the Environmental Implications of NanoTechnology (CEINT) is exploring the relationship between a vast array of nanomaterials— from natural, to manufactured, to those produced incidentally by human activities— and their potential environmental exposure, biological effects, and ecological impacts. Headquartered at Duke University, CEINT is a collaborative effort bringing together researchers from Duke, Carnegie Mellon University, Howard University, Virginia Tech, University of Kentucky, and Stanford University. CEINT academic collaborations include on-going activities coordinated with faculty at Baylor, Clemson, North Carolina State, and North Carolina Central universities, with researchers at NIST and EPA government labs, and with key international partners.

Tetramer Technologies is a research company offering polymer design and synthesis services.

Dynepic is powering corporate digital innovation, training, and engagement with its DX-Platform technology. The DX-Platform is a fully immersive app and training creation, distribution, and management platform. Founded originally as a product design firm in 2011, Dynepic had the pleasure of developing a number of products for clients, helping take them from a seed of an idea to released products. In the course of this work, Dynepic even reinvented the common handle and spun out its patented Spiral Strength grip technology to Dynepic Sports, LLC where it is the basis of a number of sporting good products.

ZillionInfo provides location intelligence solutions to help clients deal with large datasets, dig into data insights, and make better location allocation decisions such as site selection, territory mapping, and routing.

FirstString Research, Inc. is a clinical-stage biopharmaceutical company based in Mount Pleasant, South Carolina, that focuses on developing therapies for inflammation-based medical conditions. Founded in 2005, the company specializes in translating cell-cell communication and adhesion science into innovative drug applications aimed at scar prevention, inflammation reduction, wound healing, and complex tissue regeneration. FirstString holds an exclusive worldwide license for its connexin-technology platform and a portfolio of peptides that modulate junctional proteins essential for inter-cellular communication. The company has demonstrated the safety and efficacy of its lead peptide in a Phase I human clinical trial and is currently advancing Granexin Gel, a topical formulation derived from this peptide, through three Phase II clinical trials targeting scar reduction and chronic wound treatment. FirstString Research has a strategic collaboration with Relief Therapeutics SA and operates as a subsidiary of Relief Therapeutics Holding AG.

Tetramer Technologies is a research company offering polymer design and synthesis services.