Nth Cycle is a start-up focused on transforming the electronics manufacturing supply chain through innovative low-cost recycling methods. The company aims to shift the industry from a linear material model to a more efficient circular model, thereby reducing dependence on overseas mining and refining of rare earth and specialty metals. By developing an electrochemical recycling device, Nth Cycle enables the reclamation of valuable metals from end-of-life electronic devices, creating a secure domestic source for these materials. This approach not only supports the manufacturing sector but also contributes to advancements in clean energy, addressing the growing demand for sustainable practices in the recycling and electronics industries.
CodeCrew empowers kids from underrepresented communities to be tech innovators and leaders through practical, hands-on computer science training. Today, they have multiple summer camps, multiple after-school programs, eight in-school electives programs, a young adult Code School, and a number of special events.
Infusense is a platform biosensor to measure propofol levels in patients undergoing anesthesia and sedation.
Eden Concepts is a precision agriculture technology development and consulting firm based in Lenoir City, Tennessee, founded in 2018. The company focuses on enhancing farm productivity for small farmers by providing innovative solutions for vegetable and specialty crop cultivation. Its precision systems are designed to prepare and plant germinated seeds, replacing traditional methods of growing and transplanting seedlings. This approach not only improves soil health but also offers flexibility in crop selection, thereby helping farmers reduce labor costs and streamline energy-intensive farming processes.
Eonix is a manufacturer focused on developing semi-autonomous materials that streamline the design process for lithium-ion batteries. The company has introduced the ATLAS-system, an innovative research and development platform that significantly cuts down the time and costs associated with creating new materials. This system allows for the rapid design of drop-in compatible electrolyte solutions that enhance energy density and support higher voltage operations. By addressing specific challenges faced by electric vehicles, grid storage, and hybrid defense systems, Eonix aims to facilitate the adoption of clean technology and advance the performance of next-generation energy storage solutions.
Dextrous Robotics is a robotics company that develops AI-enabled warehouse robots. The company was founded in 2019 and is headquartered in Memphis, Tennessee.
Winter Innovations is focused on developing medical devices aimed at enhancing patient outcomes following orthopedic injuries. The company is working on EasyWhip, a patent-pending suturing needle specifically designed for orthopedic ligament and tendon reconstruction surgeries. This innovative device simplifies and standardizes the whip stitching technique, providing benefits such as ease of use, speed, stability, and versatility. By improving the speed and consistency of orthopedic reconstruction procedures, Winter Innovations aims to support surgeons in delivering more effective treatments for their patients.
NellOne Therapeutics, Inc. is a regenerative medicine company based in Oak Ridge, Tennessee, focused on developing and commercializing protein therapeutics aimed at restoring cardiac muscle mass and function in patients recovering from myocardial infarction and congestive cardiac failure. Established in 2007 and spun out from the U.S. Department of Energy's Oak Ridge National Laboratory, NellOne's foundation is rooted in research conducted by Dr. Cymbeline Culiat, who identified the therapeutic potential of the Nell1 gene pathway in tissue regeneration. The company’s primary goal is to translate scientific discoveries into clinical applications that improve recovery outcomes for individuals affected by heart conditions.
Active Energy Systems is leveraging its scientific expertise to develop and market an improved form of ice thermal energy storage. The company's headquarters are in Knoxville, Tennessee.
Healing Innovations, Inc. is a medical technology company founded in 2018 and based in Nashville, Tennessee. It specializes in the development and commercialization of advanced rehabilitation equipment aimed at aiding individuals recovering from spinal cord injuries, strokes, traumatic brain injuries, and other neurological conditions such as cerebral palsy, multiple sclerosis, and muscular dystrophy. The company's innovative robotic devices and software enhance the rehabilitation process, enabling clinicians to provide more effective treatment for patients with gait impairments through dynamic weight-bearing activities and locomotor therapy. Healing Innovations collaborates with leading regional innovation organizations to advance its mission of improving patient care and outcomes in various rehabilitation settings.
Couture Technologies is a software development firm that specializes in the application of AI, ML, and 3D simulation technologies. The company was founded in 2019 and is headquartered in Gallatin, Tennessee.
Cloud services have become ubiquitous to all major 21st century economic activities. However, cloud services and technologies can be significantly more powerful than they are now. A persistent barrier to further advancement has been the lack of a large-scale and open cloud research platforms. With funding from the National Science Foundation (NSF), the Chameleon project will provide such a large-scale platform to the open research community allowing them explore transformative concepts in deeply programmable cloud services, design, and core technologies. Chameleon will allow users to explore problems ranging from the creation of Software as a Service to kernel support for virtualization. This broad range of supported research includes many other areas such as developing Platforms as a Service, creating new and optimizing existing Infrastructure as a Service components, investigating software-defined networking, and optimizing virtualization technologies. The Chameleon testbed, will be deployed at the University of Chicago and the Texas Advanced Computing Center and will consist of 650 multi-core cloud nodes, 5PB of total disk space, and leverage 100 Gbps connection between the sites. While a large part of the testbed will consist of homogenous hardware to support large-scale experiments, a portion of it will support heterogeneous units allowing experimentation with high-memory, large-disk, low-power, GPU, and co-processor units. The project will also leverage existing FutureGrid hardware at the University of Chicago and the Texas Advanced Computing Center in its first year to provide a transition period for the existing FutureGrid community of experimental users. To support the broad range of experiments experiments described above, the project will support a graduated configuration system allowing full user configurability of the software stack, from provisioning of bare metal and network interconnects to delivery of fully functioning cloud environments. A special feature of Chameleon is that it provides for an exceptionally close integration of clouds and networks, which substantially enhances the capabilities of both. In addition, to facilitate experiments, Chameleon will support a set of services designed to meet researchers needs, including support for experimental management, reproducibility, and repositories of trace and workload data of production cloud workloads. The project is led by the Computation Institute at the University of Chicago and partners from the Texas Advanced Computing Center at the University of Texas at Austin, the International Center for Advanced Internet Research at Northwestern University, the Ohio State University, and University of Texas at San Antonio, comprising a highly qualified and experienced team. The team includes members from the NSF supported FutureGrid project and from the GENI community, both forerunners of the NSFCloud solicitation under which this project is funded. Chameleon will also form a set of partnerships with commercial and academic clouds, such as Rackspace, CERN and Open Science Data Cloud (OSDC), and will partner with other testbeds, notably GENI and INRIA's Grid'5000 testbed.
Crosslink Composites develops a tailor-made carbon fiber technology for a wide range of new industrial applications. The company was founded in 2017 and is headquartered in Harriman, Tennessee.
LightWorks Metrology, founded in 2019 and based in Holladay, Utah, specializes in the development of coordinate measuring machines and three-dimensional interferometer systems utilizing interferometry. The company aims to provide precision measurement solutions, enhancing accuracy in various applications. Its innovative approach combines advanced technology with a focus on quality, positioning LightWorks Metrology as a key player in the metrology sector.
Kampanics is a research and development company based in Oak Ridge, North Carolina, specializing in microacoustic devices and piezomems technology. Founded by Kushal Bhattacharjee, the firm focuses on providing services that support signal processing, sensing, and energy harvesting applications. By collaborating with academic institutions, corporate partners, and industry experts, Kampanics aims to facilitate the development of innovative products and services in the field of microacoustics.
Mobius provides environmental solutions that convert waste streams into chemicals and materials. At Mobius, we're creating a world where There’s Wonder in Waste. We’re a mission-driven company focused on eliminating waste by leveraging industrial organic waste streams from agriculture, forestry, paper and biofuel & biorefining industries to create new materials and chemicals. Our first product is a proprietary, biodegradable polymer made from lignin, a natural material found in all grasses and trees that is produced as waste at a rate of over 50 million tons each year by the paper and biofuel industries. With this biopolymer, we are creating a bio-based, biodegradable plastic pellets for applications in horticulture, agriculture, food service packaging, and beyond.
VenoStent, Inc. is a biomaterials and bioengineering company based in Nashville, Tennessee, with an additional office in Houston, Texas. Established in 2017, the company specializes in developing bioresorbable smart polymers aimed at enhancing vascular surgery outcomes. Its primary product, SelfWrap, is a perivascular wrap designed to minimize complications at the junctions of veins and arteries, particularly for dialysis patients. SelfWrap functions as an external stent that promotes outward vein growth and provides mechanical support, thereby reducing the risk of vein collapse. By focusing on innovative solutions in vascular care, VenoStent aims to improve patient outcomes and transform surgical practices.
LiBAMA develops and commercializes next-generation lithium metal batteries. The company was founded in 2017 and is headquartered in Cookeville, Tennessee.
Phase Two Chemicals is a clean chemistry company developing breakthrough technology for on-site hydrogen peroxide production.
VenoStent, Inc. is a biomaterials and bioengineering company based in Nashville, Tennessee, with an additional office in Houston, Texas. Established in 2017, the company specializes in developing bioresorbable smart polymers aimed at enhancing vascular surgery outcomes. Its primary product, SelfWrap, is a perivascular wrap designed to minimize complications at the junctions of veins and arteries, particularly for dialysis patients. SelfWrap functions as an external stent that promotes outward vein growth and provides mechanical support, thereby reducing the risk of vein collapse. By focusing on innovative solutions in vascular care, VenoStent aims to improve patient outcomes and transform surgical practices.
Nth Cycle is a start-up focused on transforming the electronics manufacturing supply chain through innovative low-cost recycling methods. The company aims to shift the industry from a linear material model to a more efficient circular model, thereby reducing dependence on overseas mining and refining of rare earth and specialty metals. By developing an electrochemical recycling device, Nth Cycle enables the reclamation of valuable metals from end-of-life electronic devices, creating a secure domestic source for these materials. This approach not only supports the manufacturing sector but also contributes to advancements in clean energy, addressing the growing demand for sustainable practices in the recycling and electronics industries.
Tennessee State University’s College of Engineering provides quality education in engineering, technology, mathematics, and computer science. It aims to produce graduates with technical competency and excellence, leadership skills, and a global life/language experience. Tennessee State University’s College of Engineering was founded in 1912.
Active Energy Systems is leveraging its scientific expertise to develop and market an improved form of ice thermal energy storage. The company's headquarters are in Knoxville, Tennessee.
SkyNano is a science-based technology company focused on commercializing a free-market solution to carbon pollution.
Stony Creek Colors, Inc. is a manufacturer of bio-based colorants specifically designed for the textile industry. Founded in 2012 and headquartered in Springfield, Tennessee, the company specializes in producing plant-based dyes, including indigo, in collaboration with small farmers in the Southeast United States. By focusing on environmentally friendly alternatives, Stony Creek Colors aims to provide clean and safe natural dyes that replace hazardous chemicals traditionally used in textile supply chains. This approach not only supports sustainable practices in the industry but also enables textile and fashion brands to offer consumers environmentally conscious premium products.
Path Ex, Inc. is a Nashville-based company that specializes in manufacturing extracorporeal blood cleansing equipment. Established in 2017, Path Ex has developed a proprietary technology designed to selectively separate and capture bacteria and toxins from human blood, specifically for the treatment of sepsis, a critical condition often resulting from blood-borne infections. This innovative approach focuses on removing intact bacteria from the bloodstream instead of relying on broad-spectrum antibiotics, making it effective against various bacteria types and drug-resistant strains. The technology aims to improve patient outcomes by reducing diagnostic times, lowering treatment costs, decreasing readmission rates, and ultimately decreasing sepsis-related fatalities.
Secure Food Solutions, Inc. is a food safety company based in Martin, Tennessee, established in 2014. The company specializes in developing advanced technologies for the rapid detection of toxins, pathogens, and other contaminants in the global food supply. Among its notable innovations is a patented hyperspectral imaging technology specifically designed to identify corn contaminated with aflatoxin. Additionally, Secure Food Solutions offers rapid microbial tests that monitor and enumerate dangerous pathogens throughout the food and water supply chains. These diagnostic tools enable clients to enhance their food safety programs and mitigate the public health risks associated with foodborne illnesses and outbreaks, all while maintaining affordability.
Vanderbilt University, founded in 1873, is a prestigious private research institution located in the United States. It serves approximately 6,500 undergraduate students and 5,300 graduate and professional students across ten schools. The university is renowned for its Peabody College, which is ranked as the top Graduate School of Education by U.S. News and World Report. Vanderbilt offers a diverse range of undergraduate programs in liberal arts, sciences, engineering, music, education, and human development, along with comprehensive graduate and professional degrees. The institution consistently ranks among the top 20 universities in the nation, with numerous programs recognized within the top 10 across various disciplines. In addition to its educational offerings, Vanderbilt is home to a distinguished medical center, a public policy center, and The Freedom Forum First Amendment Center, further enhancing its role as a leader in research and education.
Vana Learning's (SaaS) platform helps tutors, academic coaches, and teachers improve student academic outcomes and grow their businesses by simplifying processes and hosting features including behavior tracking, visualizations, and actionable insights.
Mobius provides environmental solutions that convert waste streams into chemicals and materials. At Mobius, we're creating a world where There’s Wonder in Waste. We’re a mission-driven company focused on eliminating waste by leveraging industrial organic waste streams from agriculture, forestry, paper and biofuel & biorefining industries to create new materials and chemicals. Our first product is a proprietary, biodegradable polymer made from lignin, a natural material found in all grasses and trees that is produced as waste at a rate of over 50 million tons each year by the paper and biofuel industries. With this biopolymer, we are creating a bio-based, biodegradable plastic pellets for applications in horticulture, agriculture, food service packaging, and beyond.
PurSolutions is a biotechnology startup that specializes in cytoskeletons for self-assembling materials and devices. The company was founded in 2015 and is based in Nashville, Tennessee.
Path Ex, Inc. is a Nashville-based company that specializes in manufacturing extracorporeal blood cleansing equipment. Established in 2017, Path Ex has developed a proprietary technology designed to selectively separate and capture bacteria and toxins from human blood, specifically for the treatment of sepsis, a critical condition often resulting from blood-borne infections. This innovative approach focuses on removing intact bacteria from the bloodstream instead of relying on broad-spectrum antibiotics, making it effective against various bacteria types and drug-resistant strains. The technology aims to improve patient outcomes by reducing diagnostic times, lowering treatment costs, decreasing readmission rates, and ultimately decreasing sepsis-related fatalities.
Phase Two Chemicals, operating under Peroxygen Systems, Inc., is focused on developing innovative electrochemical systems for on-site production of low-cost chemical oxidizers, primarily hydrogen peroxide. Founded in 2014 and based in Knoxville, Tennessee, the company’s technology allows for a significant reduction in production costs—over 50%—while addressing safety concerns related to the transportation and handling of high-concentration hydrogen peroxide. The electrochemical process not only enhances energy efficiency in hydrogen peroxide production but also minimizes the environmental waste typically generated by traditional chemical synthesis methods. Through these advancements, Phase Two Chemicals aims to promote cleaner and more sustainable chemical practices.
Secure Food Solutions, Inc. is a food safety company based in Martin, Tennessee, established in 2014. The company specializes in developing advanced technologies for the rapid detection of toxins, pathogens, and other contaminants in the global food supply. Among its notable innovations is a patented hyperspectral imaging technology specifically designed to identify corn contaminated with aflatoxin. Additionally, Secure Food Solutions offers rapid microbial tests that monitor and enumerate dangerous pathogens throughout the food and water supply chains. These diagnostic tools enable clients to enhance their food safety programs and mitigate the public health risks associated with foodborne illnesses and outbreaks, all while maintaining affordability.
Branch Technology, Inc. is a Chattanooga, Tennessee-based company specializing in cellular fabrication technology through advanced 3D printing. Founded in 2014 by Christopher W. Weller and Platt Boyd, the company focuses on creating innovative architectural components such as decorative walls, non-loadbearing interior partitions, ceilings, and furniture. Utilizing proprietary algorithms, Branch Technology constructs complex geometries in open spaces without the need for support materials or highly controlled environments. This unique approach allows for the development of structures that traditional construction methods cannot achieve, resulting in cost-effective designs with improved material strength, reduced energy consumption, and enhanced job site efficiency.
Stony Creek Colors, Inc. is a manufacturer of bio-based colorants specifically designed for the textile industry. Founded in 2012 and headquartered in Springfield, Tennessee, the company specializes in producing plant-based dyes, including indigo, in collaboration with small farmers in the Southeast United States. By focusing on environmentally friendly alternatives, Stony Creek Colors aims to provide clean and safe natural dyes that replace hazardous chemicals traditionally used in textile supply chains. This approach not only supports sustainable practices in the industry but also enables textile and fashion brands to offer consumers environmentally conscious premium products.
Volumetrix focuses on creating innovative non-invasive monitoring technologies designed to improve individual well-being. The company develops sensors that capture venous waveforms, allowing for the assessment of various physiological conditions. This technology enables clinicians to accurately monitor patient health and detect congestion in diverse settings, including hospitals and homes. Volumetrix collaborates closely with patients and healthcare practitioners to ensure effective implementation and utilization of its monitoring solutions.
Branch Technology, Inc. is a Chattanooga, Tennessee-based company specializing in cellular fabrication technology through advanced 3D printing. Founded in 2014 by Christopher W. Weller and Platt Boyd, the company focuses on creating innovative architectural components such as decorative walls, non-loadbearing interior partitions, ceilings, and furniture. Utilizing proprietary algorithms, Branch Technology constructs complex geometries in open spaces without the need for support materials or highly controlled environments. This unique approach allows for the development of structures that traditional construction methods cannot achieve, resulting in cost-effective designs with improved material strength, reduced energy consumption, and enhanced job site efficiency.
Coulometrics specializes in manufacturing and providing services for the battery and ultracapacitor industries. The company produces battery electrodes, cylindrical batteries, and pouch cells, and offers a comprehensive suite of battery testing services, including safety testing, cycle life testing, and high precision coulometry. This facilitates support for material development companies, battery manufacturers, and end-users by assisting in the development of new materials, formulations, and processes. Additionally, Coulometrics operates a toll coating and converting line that is fully operational, available for mixing, coating, calendaring, and slitting needs, and is actively accepting reservations for coating trials to advance technology within the sector.
Eonix is a manufacturer focused on developing semi-autonomous materials that streamline the design process for lithium-ion batteries. The company has introduced the ATLAS-system, an innovative research and development platform that significantly cuts down the time and costs associated with creating new materials. This system allows for the rapid design of drop-in compatible electrolyte solutions that enhance energy density and support higher voltage operations. By addressing specific challenges faced by electric vehicles, grid storage, and hybrid defense systems, Eonix aims to facilitate the adoption of clean technology and advance the performance of next-generation energy storage solutions.
490 BioTech is a life sciences company that develops patent protected light-emitting (bioluminescent) human cell lines genetically programmed to ‘report’ on biological events or interactions that affect their metabolic status. The incorporation of these cell lines into cell culture and small animal preclinical efficacy/toxicity testing models is designed to accelerate the pace of new drug discovery and move drugs more rapidly and more effectively towards Phase I human testing with a reduced overall cost.
Coulometrics specializes in manufacturing and providing services for the battery and ultracapacitor industries. The company produces battery electrodes, cylindrical batteries, and pouch cells, and offers a comprehensive suite of battery testing services, including safety testing, cycle life testing, and high precision coulometry. This facilitates support for material development companies, battery manufacturers, and end-users by assisting in the development of new materials, formulations, and processes. Additionally, Coulometrics operates a toll coating and converting line that is fully operational, available for mixing, coating, calendaring, and slitting needs, and is actively accepting reservations for coating trials to advance technology within the sector.