National Science Foundation
The National Science Foundation (NSF), established in 1950 and located in Alexandria, Virginia, is an independent federal agency dedicated to advancing fundamental research and education across all scientific and engineering disciplines. With an annual budget of approximately $7.8 billion, the NSF operates America's Seed Fund, which allocates nearly $200 million each year to support startups and small businesses through the Small Business Innovation Research (SBIR) program. This initiative provides non-dilutive funding of up to $1.5 million to assist in research and development efforts, thereby facilitating the transformation of scientific discoveries into commercially viable products and services. By helping to de-risk technology, the NSF plays a crucial role in fostering innovation and addressing societal challenges through scientific advancements.
OPOS operates a patient monitoring and opioid prescriber compliance platform designed to assist primary care and pain specialists across various practice settings. The company focuses on ensuring that opioid prescribers adhere to guidelines set by the Centers for Disease Control and Prevention, state authorities, and medical boards. By providing documented evidence of compliance, along with clinical decision support, OPOS enables healthcare providers to enhance patient outcomes and assess individual and collective risks associated with patients, prescribers, and practices. Their services not only promote regulatory compliance but also aim to reduce prescribing risks and administrative overhead, thus generating revenue through improved operational efficiency in opioid treatment.
ColoWrap, LLC is a medical device company based in Durham, North Carolina, focused on enhancing the colonoscopy experience. Founded in 2012, the company has developed a non-invasive device designed to prevent looping in the colon during procedures. This device applies sustained, adjustable pressure to the lower abdomen, specifically targeting the sigmoid and transverse colon, which reduces the need for manual pressure and frequent patient repositioning. Made from latex-free materials similar to those used in high-performance wetsuits, the device aims to improve patient comfort while allowing medical practitioners to perform colonoscopies with minimal invasion.
OsciFlex LLC, founded in 2017 and based in Philadelphia, Pennsylvania, specializes in developing medical devices aimed at preventing blood clots, particularly at the valves. The Osciflex system mimics natural processes to reduce the risk of venous thromboembolism (VTE) in patients, providing an innovative alternative to traditional compression therapy. By enhancing the effectiveness of compression therapy, OsciFlex seeks to minimize the reliance on costly and potentially hazardous anticoagulant medications.
AbiliLife, Inc. is a Pennsylvania-based company focused on creating biomedical solutions for individuals suffering from neurodegenerative disorders, particularly Parkinson's disease. Incorporated in 2014, AbiliLife designs and manufactures innovative products aimed at enhancing the quality of life for patients. One of its key offerings is Calibrace, a specialized brace that assists patients in restoring equilibrium through a back tensioning system. This product is designed to improve posture, positioning, and balance, providing users with postural stability and relief from discomfort associated with neurodegenerative conditions.
DoseCue is a medication adherence company. DoseCue is proven to increase medication adherence without adding steps to patients’ dose-taking routine. Increasing medication adherence fosters better health outcomes for patients, which reduces costs for health insurance providers and sponsors. DoseCue containers are programmed when filled and are ready to go when received, so there are no additional steps for patients; they simply follow the lights. The top light flashes green at dose time, the second flashes green when a dose is taken, the third flashes red if a dose is missed, and the fourth flashes yellow when it’s time to order a refill.
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