National Science Foundation

The National Science Foundation (NSF), established in 1950 and located in Alexandria, Virginia, is an independent federal agency dedicated to advancing fundamental research and education across all scientific and engineering disciplines. With an annual budget of approximately $7.8 billion, the NSF operates America's Seed Fund, which allocates nearly $200 million each year to support startups and small businesses through the Small Business Innovation Research (SBIR) program. This initiative provides non-dilutive funding of up to $1.5 million to assist in research and development efforts, thereby facilitating the transformation of scientific discoveries into commercially viable products and services. By helping to de-risk technology, the NSF plays a crucial role in fostering innovation and addressing societal challenges through scientific advancements.

James Donlon

Program Director

Sean L. Jones

Assistant Director for Mathematical and Physical Sciences

Sethuraman Panchanathan

Director

Ben Schrag Ph.D

Program Director and Policy Liaison, SBIR / STTR

Past deals in Software

BrilliantMD

Grant in 2022
Developer of a claim management software designed to solve healthcare problems of claims denials. The company's software uses artificial intelligence, machine learning, blockchain technology and advanced analytics to provide transparency to healthcare data for revenue in the claims process, enabling customers to increase revenue and transform data-driven decisions and insights.

Brainsoft

Grant in 2022
Brainsoft specializes in the development of technologies that leverage human brainwaves to control objects and analyze the relationship between brain activity and emotional and intellectual states. The company creates innovative interfaces that enable intuitive navigation, allowing users to interact with devices based on their mental and emotional conditions. By focusing on the interception and analysis of brainwaves, Brainsoft aims to support researchers in advancing their understanding of brain activity, ultimately benefiting society through improved insights into human cognition and behavior.

LangInnov

Grant in 2021
Developer of a language application intended to assist the development of bilingualism. The company's application is a user-friendly, fully automated, multi-platform, language and literacy assessment for emergent bilinguals to respond in English and their home language, enabling users to learn reading, writing, listening, speaking, and cognitive skills.

OnSystem Logic

Grant in 2021
Developer of security software designed to prevent malware and application vulnerabilities from compromising computer systems. The company's software offers a non-bypassable application hardening ability that works within existing software to protect against cyber threats, enabling businesses to have a preventative layer of defense.

Aliro Security

Grant in 2021
Aliro Technologies, Inc. develops and offers cloud based software-as-a-service platform for coding in quantum environment. The company's platform enables coders with hardware-independent toolkit for developers of quantum algorithms and applications to be used in quantum computers. Aliro Technologies, Inc. was founded in 2019 and is headquartered in Boston, Massachusetts.

Radiologics

Grant in 2020
Developer of clinical trial software designed to provide image data management for clinical trials. The company's platform provides file transfer and verification, integration with clinical data, automation of image processing routines and connectivity, helping health professionals with clinical research and diagnostics.

Docugami

Grant in 2020
Docugami, Inc. is an artificial intelligence document engineering company based in Kirkland, Washington, established in 2017. The company specializes in developing software-as-a-service (SaaS) solutions that utilize various AI techniques, such as natural language processing, image recognition, and declarative markup. These tools are designed to help businesses of all sizes enhance their document creation and management processes, leading to improved insight, efficiency, and overall business impact. Through its innovative approach, Docugami aims to transform how organizations handle their unique documents, making the process more effective and impactful.

Oscilloscape, LLC

Grant in 2020
Oscilloscape, LLC is a technology company based in Hartford, Connecticut, that specializes in the analysis of audio and other time-based signals, including music and speech. Founded in 2016, the company has developed a platform that simulates networks of active elements resembling small populations of neurons in the brain, utilizing nonlinear dynamical systems. Its offerings include the Synchrony LEDS, which synchronizes oscillations to music and detects beats in real time, and the GrFNN API, a software library designed for simulating signal processing, pattern recognition, and auditory system learning. Formerly known as Circular Logic, LLC, Oscilloscape focuses on enhancing rhythmic intelligence for human interaction.

Aqueduct Fluidics

Grant in 2020
Aqueduct Fluidics, founded in 2019 and headquartered in Philadelphia, PA, specializes in developing automation solutions tailored for physical and life sciences research on laboratory benchtops. The company offers a software automation tool designed to streamline workflows and enhance the integration of hardware components. Its platform enables users to write automation scripts and provides an intuitive interface for controlling and visualizing hardware status. By simplifying system integration and addressing complex elements such as communication protocols, command timing, user interfaces, and data management, Aqueduct Fluidics equips developers with the necessary tools and resources to efficiently create, test, and deploy automation programs for benchtop-scale applications.

SandBox Semiconductor

Grant in 2020
SandBox Semiconductor specializes in developing software tools aimed at enhancing the manufacturing process for semiconductor production. Their innovative software enables process engineers to identify optimal etch and deposition recipes with significantly fewer experiments, achieving this in one-third of the time and at a reduced cost compared to traditional methods. By streamlining recipe development, SandBox Semiconductor facilitates quicker deployment of new microelectronic devices, thereby improving efficiency and productivity in the semiconductor manufacturing industry.

JuliaHub

Grant in 2020
Julia Computing, Inc. specializes in designing and developing software solutions for the Julia programming language, catering to a diverse audience including professionals, engineers, and data scientists. Its offerings include JuliaPro for advanced users, JuliaRun for scalable deployment in production environments, JuliaBox for educational purposes, and JuliaFin, which provides tools for quantitative finance. The company also delivers tailored consulting services, encompassing software development, integration, and performance engineering. Additionally, Julia Computing provides training programs ranging from basic to advanced levels for users of the Julia language. Founded in 2013, the company is headquartered in Newton, Massachusetts, with offices in various locations including Boston, New York, London, San Francisco, Los Angeles, Washington DC, and Bengaluru, India. Julia itself is a high-performance programming language that has gained significant traction, with over 20 million downloads and a growing ecosystem of more than 4,000 packages.

Lotic Labs

Grant in 2019
Lotic Labs develops innovative software focused on enhancing water markets and advancing environmental finance. By integrating fragmented data sets with advanced environmental science models and financial simulations, Lotic Labs facilitates comprehensive analysis of the interplay between financial, operational, and environmental decisions, particularly within the water utility and heavy industrial sectors. The company’s technology is designed to address environmental financial risks, offering tools for climate risk assessment that help minimize revenue and budget variance for water utilities. Additionally, Lotic Labs provides solutions for environmental modeling and analytics, including contract simulation, impact tracking, and opportunity identification, enabling businesses that rely heavily on natural resources to effectively manage the risks associated with volatile environmental conditions.

LangInnov

Grant in 2019
Developer of a language application intended to assist the development of bilingualism. The company's application is a user-friendly, fully automated, multi-platform, language and literacy assessment for emergent bilinguals to respond in English and their home language, enabling users to learn reading, writing, listening, speaking, and cognitive skills.

BrilliantMD

Grant in 2019
Developer of a claim management software designed to solve healthcare problems of claims denials. The company's software uses artificial intelligence, machine learning, blockchain technology and advanced analytics to provide transparency to healthcare data for revenue in the claims process, enabling customers to increase revenue and transform data-driven decisions and insights.

Ultorg

Grant in 2019
Ultorg creates general-purpose software that helps organizations manage their data. Based on a new method for interactive data visualization, our product combines ease-of-use with expressive power to allow end-users to query, display, and edit relational data, without resorting to custom programming. This fills a long-standing gap between spreadsheets and tailor-made database applications.

Geospiza

Grant in 2019
Geospiza is a tech startup that changes the way crisis and emergency management decisions are made. The Geospiza software platform integrates real-time IoT, big data, advanced analytics, and evidence-based consequence projections to support decision making that saves lives and protects the environment.

Comake

Grant in 2018
Comake is a software platform that addresses the challenges faced by modern knowledge workers who navigate multiple communication channels and fragmented information systems. By consolidating and contextualizing digital information from various sources, Comake provides users with a single interface to view, search, communicate, share, and collaborate on content. The platform automatically maps emails, messages, files, and tasks to relevant employees, clients, and projects, enhancing internal communication and fostering valuable connections across organizations. As more collaborators join, the platform's utility increases, making it an effective tool for improving workflow and collaboration within teams.

Teton Simulation

Grant in 2018
Developer of a software technology designed to enable automatic validation and optimization of 3D print parameters. The company's technology is used to replace the standard print-break-repeat prototyping cycle in order to speed development and reduce the time and cost of production, enabling users to develop applications through structural behavior and progressive failure analysis.

Saber Corporation

Grant in 2018
Saber Software Corporation develops and markets PC utility software products for local area networks.

SandBox Semiconductor

Grant in 2018
SandBox Semiconductor specializes in developing software tools aimed at enhancing the manufacturing process for semiconductor production. Their innovative software enables process engineers to identify optimal etch and deposition recipes with significantly fewer experiments, achieving this in one-third of the time and at a reduced cost compared to traditional methods. By streamlining recipe development, SandBox Semiconductor facilitates quicker deployment of new microelectronic devices, thereby improving efficiency and productivity in the semiconductor manufacturing industry.

Albeado

Grant in 2018
Albeado provides a software platform that allows an organization to understand its business process control knobs. The company helps them make connections between the knobs putting more control and fast effective decision-making power at their fingertips. It was founded in 2010 and headquartered in Saratoga, California.

QC Ware

Grant in 2018
QC Ware, Corp. develops enterprise applications for quantum computers, offering hardware-agnostic software solutions that address challenges in combinatorial optimization and machine learning. Founded in 2014 and headquartered in Palo Alto, California, with an additional office in Paris, France, the company provides a graphical web application that serves various sectors, including finance, deep learning, network and cybersecurity, and hybrid computing platforms. Its software is designed to enhance efficiency beyond traditional high-performance computing solutions, making it suitable for enterprise, government, and academic clients.

AutoModality

Grant in 2017
AutoModality Inc. specializes in developing flight control software for unmanned aerial vehicles (UAVs) that allows these systems to operate autonomously in GPS-denied environments. Founded in 2014 and based in Syracuse, New York, the company focuses on providing technology for automated close-up inspections, particularly in the agriculture and infrastructure sectors. AutoModality's software enables drones to navigate challenging locations, such as bridges, culverts, and cell towers, while delivering live streaming data to users, facilitating detailed inspections comparable to those conducted by human operators. The company also manufactures drone platforms that utilize off-the-shelf components, enhancing their inspection capabilities.

Stocastic

Grant in 2017
StoCastic develops healthcare enterprise software that benefits both patients and healthcare organizations. The company was founded in 2015 and is based in Towson, Maryland.

Teton Simulation

Grant in 2017
Developer of a software technology designed to enable automatic validation and optimization of 3D print parameters. The company's technology is used to replace the standard print-break-repeat prototyping cycle in order to speed development and reduce the time and cost of production, enabling users to develop applications through structural behavior and progressive failure analysis.

SciArt Software

Grant in 2017
SciArt Software, Inc. specializes in developing topology optimization software that enhances the design process for physical parts through generative design. Founded in 2018 and based in Madison, Wisconsin, the company offers a range of products including ParetoCreo, an add-in for design analysis; ParetoWin, a CAD-agnostic topology optimization tool; ParetoCloud, a cloud-based solution for finite element analysis and topology optimization; and ParetoWorks, a subscription service for design analysis. SciArt's technology allows users to optimize material distribution based on specific strength and functionality requirements, significantly reducing manufacturing costs while preserving structural integrity. The software delivers insights to engineers approximately 60 times faster than traditional solutions, effectively doubling the design cycle speed.

QC Ware

Grant in 2016
QC Ware, Corp. develops enterprise applications for quantum computers, offering hardware-agnostic software solutions that address challenges in combinatorial optimization and machine learning. Founded in 2014 and headquartered in Palo Alto, California, with an additional office in Paris, France, the company provides a graphical web application that serves various sectors, including finance, deep learning, network and cybersecurity, and hybrid computing platforms. Its software is designed to enhance efficiency beyond traditional high-performance computing solutions, making it suitable for enterprise, government, and academic clients.
Developer of a textile visualization and manufacturing software created for designers to have easy access to textile manufacturing. The company's software offers a Web application and manufacturing process that enables anyone to transform design ideas into intricately patterned woven cloth, one yard or 100 yards at once, enabling textile manufacturing industry to access advanced 3D rendering tools which has become an essential part of the market for printed textiles, to a new higher-value segment for professional applications.

Albeado

Grant in 2016
Albeado provides a software platform that allows an organization to understand its business process control knobs. The company helps them make connections between the knobs putting more control and fast effective decision-making power at their fingertips. It was founded in 2010 and headquartered in Saratoga, California.

Symbyon Systems

Grant in 2016
Symbyon develops enterprise software and intellectual property for advanced error correction coding and machine learning. This technology has been proven and has been already deployed in storage devices. Their work resulting is the top choice for IEEE P1890 Standards for Error Correction Coding for Non-Volatile Memories. They are working with commercial partners to design their solution tailored to specific requirements for new applications.

OpenRefactory

Grant in 2016
Developer of intelligent code repair tool designed to fix bugs and avoid threatening security. The company's tool helps software developers achieve higher security, reliability, and compliance goals by analyzing source code to detect and automatically fix critical programming errors, enabling businesses to meet the secure coding standard for security and reliability.

Fluidity Software

Grant in 2016
Fluidity Software enables teachers and students to easily create, solve, graph, and animate math and physics problems. Since 2005, Fluidity Software, Inc. has been researching, designing, developing, marketing, and selling state of the art education and scientific visualization systems aimed at revolutionizing the way people learn. Fluidity has achieved considerable success in acquiring funding from the federal government to pursue the research and development of its core products. This funding has come in the form of grants and contracts from the U.S. Department of Education, the National Institutes of Health (NIH), and the National Science Foundation (NSF).

Stocastic

Grant in 2016
StoCastic develops healthcare enterprise software that benefits both patients and healthcare organizations. The company was founded in 2015 and is based in Towson, Maryland.

Arogi, Inc.

Angel Round in 2016
Arogi builds open source software for developers to optimize site location, routing, and logistics. Integrating geospatial analyses and artificial intelligence, Arogi tools enable organizations to save time, reduce costs, and increase market share.

DataWare Ventures

Grant in 2015
Dataware Ventures is a software company that is developing a technology to help enterprise application software (EAS) vendors optimize the performance of their applications. Our patent-pending micro-specialization technology addresses the major pain points of EAS, including slow data loads and slow query performance. Our technology is targeted towards CRM, ERP, HR, and big data analytics applications, as well as their underlying database management systems (DBMS), which are used by virtually every medium and large business.

CHI Systems, Inc.

Grant in 2015
CHI Systems is a computer software company that provides big data analytics, instructional analysis, and design solutions.

SecondWrite

Grant in 2015
SecondWrite LLC specializes in creating automated malware analysis solutions aimed at detecting advanced persistent threats (APTs), targeted attacks, and zero-day evasions. The company's flagship product, the SecondWrite Sandbox, is designed to identify evasive malware, capture indicators of compromise (IOCs), and process various file types while integrating seamlessly with existing security systems. Founded in 2010 and based in College Park, Maryland, SecondWrite serves a diverse clientele that includes network security providers, endpoint security firms, security operations centers (SOCs) at enterprises, managed security service providers (MSSPs), incident response teams, and threat intelligence vendors. The company's technology, developed in collaboration with university partners, employs a patent-pending approach that reveals hidden paths in malware and executes them to ensure comprehensive code coverage.

Symbyon Systems

Grant in 2015
Symbyon develops enterprise software and intellectual property for advanced error correction coding and machine learning. This technology has been proven and has been already deployed in storage devices. Their work resulting is the top choice for IEEE P1890 Standards for Error Correction Coding for Non-Volatile Memories. They are working with commercial partners to design their solution tailored to specific requirements for new applications.

Aventusoft

Grant in 2015
AventuSoft is a pioneer in biologically inspired solutions! Our mission, is to continuously enhance the efficiency and function of people through advanced biologically inspired engineering. The human auditory system is an existence proof for accurate speech processing and has solved the principal complexities that currently plague speech processing solutions: multiple sources, noisy environments, and mismatched test/train data. Solutions by AventuSoft, are developed by applying in-depth knowledge of psychoacoustics, biological signals, and novel signal processing techniques to leverage the benefits seen in human system.

SecondWrite

Grant in 2014
SecondWrite LLC specializes in creating automated malware analysis solutions aimed at detecting advanced persistent threats (APTs), targeted attacks, and zero-day evasions. The company's flagship product, the SecondWrite Sandbox, is designed to identify evasive malware, capture indicators of compromise (IOCs), and process various file types while integrating seamlessly with existing security systems. Founded in 2010 and based in College Park, Maryland, SecondWrite serves a diverse clientele that includes network security providers, endpoint security firms, security operations centers (SOCs) at enterprises, managed security service providers (MSSPs), incident response teams, and threat intelligence vendors. The company's technology, developed in collaboration with university partners, employs a patent-pending approach that reveals hidden paths in malware and executes them to ensure comprehensive code coverage.

Aventusoft

Grant in 2013
AventuSoft is a pioneer in biologically inspired solutions! Our mission, is to continuously enhance the efficiency and function of people through advanced biologically inspired engineering. The human auditory system is an existence proof for accurate speech processing and has solved the principal complexities that currently plague speech processing solutions: multiple sources, noisy environments, and mismatched test/train data. Solutions by AventuSoft, are developed by applying in-depth knowledge of psychoacoustics, biological signals, and novel signal processing techniques to leverage the benefits seen in human system.

Salgomed

Grant in 2013
Salgomed Inc develops algorithms for use in combined drug interventions in multi-drug therapies. The company was founded in 2009 and is based in Del Mar, California.

Telestream

Grant in 2013
Telestream provides live and on-demand digital video tools and workflow solutions that allow consumers and businesses to transform videos on the desktop and across the enterprise. Its customers include media and entertainment companies, enterprises, professionals, and individual users, who use its products to reach broader audiences, streamline operations, and generate more revenue from their media. Telestream’s products include hardware and software for video capture and ingest; live and on-demand encoding and transcoding; and playout, delivery, live streaming, and screencasting as well as management and automation of the entire digital media workflow. It was launched in 1998 and is based in Nevada City, C.A.

Zipreel

Grant in 2013
Zipreel is a software development company based in Princeton, New Jersey, focused on creating reliable and scalable solutions for media processing. The company specializes in media classification, transcoding, and metadata generation, providing tools that enhance the efficiency and effectiveness of media management. By leveraging advanced technology, Zipreel aims to streamline the handling of media assets, making it easier for businesses to organize and utilize their digital content.

Signalogic

Grant in 2013
Signalogic is a leader in the development of efficient, low SWaP, HPC solutions for the server and embedded systems markets. Through their work with key business customers, channel partners and government agencies, they are advancing the use of HPC computing for a new generation of compute intensive applications.

SecondWrite

Grant in 2013
SecondWrite LLC specializes in creating automated malware analysis solutions aimed at detecting advanced persistent threats (APTs), targeted attacks, and zero-day evasions. The company's flagship product, the SecondWrite Sandbox, is designed to identify evasive malware, capture indicators of compromise (IOCs), and process various file types while integrating seamlessly with existing security systems. Founded in 2010 and based in College Park, Maryland, SecondWrite serves a diverse clientele that includes network security providers, endpoint security firms, security operations centers (SOCs) at enterprises, managed security service providers (MSSPs), incident response teams, and threat intelligence vendors. The company's technology, developed in collaboration with university partners, employs a patent-pending approach that reveals hidden paths in malware and executes them to ensure comprehensive code coverage.

TestWorks

Grant in 2012
TestWorks is a social enterprise based in Seoul, Korea, specializing in innovative solutions for AI data processing and software testing. The company focuses on creating tools that enhance business software delivery and testing through automation and artificial intelligence. Their offerings include services for collecting, annotating, and managing training datasets, which are essential for AI training and verification. TestWorks is recognized for its technical excellence and commitment to quality, making it a leader in the data processing sector. Additionally, the company promotes an inclusive employment model by providing opportunities for socially disadvantaged individuals, aligning its business objectives with social responsibility.
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