MedTech Innovator

Endiatx is a medical device manufacturing company that specializes in developing a series of pill-sized robots to perform remote diagnosis. Its unique propulsion system which allows our pill robots to actively navigate the entire length of the GI tract is approximately 30 minutes with real-time video control. It was founded in 2019 and headquartered in Redwood City, California.

Endoron Medical specializes in the development of innovative medical devices aimed at improving the treatment of abdominal aortic aneurysms. The company has created an endovascular suture-like device designed for use in endovascular aneurysm repair. This fixation device enhances the performance of endografts, providing a more effective and durable sealing solution. By leveraging advanced technology, Endoron Medical aims to facilitate better patient outcomes during procedures for abdominal aortic aneurysms, thereby addressing a critical need in vascular surgery.

CardiaCare is focused on developing a wearable medical device aimed at the non-invasive treatment and monitoring of atrial fibrillation (AFib) in patients. Utilizing a closed-loop approach and machine learning algorithms, the device applies personalized peripheral neuromodulation to elicit a cardiovascular antiarrhythmic response. This innovative technology enables users to effectively reduce the burden of atrial fibrillation and mitigate its precursors, such as premature atrial contractions. As a result, patients can experience rapid clinical and symptomatic relief while managing their condition from the comfort of their homes.

MastOR SAS is a medical device company based in Paris, France, founded in 2019. The company focuses on developing a surgical robot designed to assist with laparoscopy, a minimally invasive surgical technique. This innovative platform aims to enhance access to advanced surgical procedures for surgeons and improve resource utilization in operating rooms. By providing tools that facilitate laparoscopy, MastOR seeks to advance surgical practices and patient care.

52 North Health is focused on enhancing healthcare for cancer patients, specifically those undergoing chemotherapy, by providing a portable and easy-to-use medical device. This device employs artificial intelligence to assess the risk of neutropenic sepsis, a serious and potentially fatal side effect of chemotherapy. Through a finger prick blood test and a corresponding digital platform, the device measures a patient's neutrophil count and C-reactive protein (CRP) levels at home. This functionality allows for timely identification of patients at risk of sepsis, thereby improving their safety and quality of life. By facilitating rapid management of their condition, 52 North Health offers a reliable and cost-effective solution for cancer patients.

Aqua Medical, Inc. develops a disruptive, vapor-based, endoscopic, ablation technology to treat gastrointestinal (GI) disease and prevent GI cancers. Its ablation technology includes high temperature water vapor created by a radio frequency generator and delivered endoscopically through proprietary catheters to the GI tract. The company’s platform technology uses a vapor generator system with two catheter types to deliver treatment for multiple diseases throughout the GI tract. The company was incorporated in 2016 and is based in Santa Ana, California.

Phiex Technologies on-demand, interactive materials for efficient and cost-effective medical device manufacturing, food safety and packaging, and innovations for pathogens.

Healthcare X.0 is an online healthcare platform that provides its clients with digitization solutions. The platform provides its clients with health, vascular, patient, onco, nephro, cardio, wound, tele, patient, and diabetic assist database solutions. Healthcare X.0 was launched in 2013 by and is based in Niedersachsen.

LiveMetric is a medical device company developing non-invasive sensing and deep data analytics solutions. The company transforming the care and condition-management of hypertension and cardiovascular diseases. Using their own proprietary, non-invasive arterial pressure technology, they provide a wearable, non-invasive medical device which enables AI-augmented care and condition management treatment services management. LiveMetric delivers high fidelity arterial pressure waveforms and detailed activity mapping of the single user at any time. They seek to empower individuals, payors, self-insured employers and healthcare providers with an accurate, fact-based, personalized care platform that has the potential for improving the care and lives of over 1 Billion people worldwide who suffer from these conditions. The company's goal is to provide prescribed patients, caregivers, and payors with pertinent data and detailed daily activity mapping.

Robotic Hospital Nutrition Management Systems

Anumana is an AI-driven company that develops ECG algorithms enabling early disease diagnosis and intervention. Anumana harnesses industry-leading AI and translational science to decode the electrocardiogram (ECG) – like a deep predictive tool and biomarker of disease, empowering care providers to help patients early.

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Indago is a biotechnology company that creates the operating room of the future through smart surgical tools. For surgeons who struggle with cumbersome wires and outdated technology, they built ArthroFree, a fully wireless visualization platform with an attractive cost profile that integrates into existing OR workflows, allowing physicians to focus on patients and procedures, not their tools. The company was founded in 2015 and is headquartered in Cleveland, Ohio, United States.

Augment Health is a medical device company in the southeast United States. Augment Health is focused on improving patient quality of life and care outcomes, initially focused on the population of catheter users with limited bladder sensation. They have developed a bladder management system that lets patients know when they need to go.

Leadoptik is a California-based company operating in stealth mode, focused on developing advanced miniature imaging technology for minimally invasive medical procedures. This innovative technology enhances surgeons' ability to view small objects with improved clarity compared to existing imaging systems, offering 3D navigation capabilities and high-resolution imaging. By facilitating the early detection of cancer in patients, Leadoptik aims to significantly improve surgical outcomes and patient care.

CARI Health is a digital health company based in San Diego, California, that specializes in the development of remote medication monitors. Founded in 2015 and incorporated in 2021, the company creates wireless sensors that patients wear on their skin. These sensors continuously transmit real-time data about medication levels to the cloud, allowing clinicians to safely prescribe, dose, and monitor adherence to critical medications. By providing this innovative solution, CARI Health aims to enhance patient care and improve health outcomes through better medication management.

Endoluxe, Inc. manufactures a portable device to perform endoscopic procedures. The company’s EVS system offers features, such as wireless display, HD camera, voice activation, and auto image stabilization with applications in Urology, Gynecology, Pulmonology, and Orthopedics. Endoluxe, Inc. was incorporated in 2013 and is based in Dunwoody, Georgia.

Gradient Denervation Technologies develops a endovascular catheter-based medical device to treat pulmonary hypertension. Its medical device aims at reducing pulmonary vascular resistance and improving cardiovascular hemodynamics. The company was incorporated in 2019 and is based in Paris, France.

Operator of a microbiology research company intended to democratize molecular biology by moving complex molecular biology tools out of highly skilled laboratories to non-laboratory settings. The company's innovative enzymatic approach to nucleic acid extraction offers sample preparation suitable for PCR (polymerase chain reaction) analysis, enabling clients to create the next generation of person-portable diagnostic devices for the management of infectious diseases and other personalized medicine applications.

TrackX Technology develops a tracking technology that provides real-time virtual live fluoroscopy. It focuses on creating profound procedurally driven imaging solutions that provide priceless benefits to the surgeon, hospital, and entire operating room.

Garwood Medical Devices, LLC develops and manufactures medical devices related to infection, perio-prosthetic, and wound healing. It offers BioPrax, a minimally invasive device that targets and eliminates biofilm infections on prosthetic knee implants during early intervention procedures. Garwood Medical Devices, LLC was formerly known as Enermed, LLC and changed its name to Garwood Medical Devices, LLC in December 2015. Garwood Medical Devices, LLC was incorporated in 2014 and is based in Buffalo, New York.

Bright Uro is an early-stage medical technology company. It is building the next generation of diagnostic devices for Urology. Utilizing advanced hardware, software, and data science can unlock new data streams and offer actionable insight for clinicians.

New View Surgical, Inc. is a Boston-based medical device company that specializes in the development and commercialization of the VisionPort technology, a novel surgical imaging and access system designed for minimally invasive surgery. Founded in 2009, the company has created a proprietary system that integrates four essential devices—a laparoscope, camera, light source, and access port—into a single, easy-to-use, and disposable unit. This innovation aims to provide surgeons with enhanced control over visualization and instrumentation during procedures, addressing various unmet needs within the surgical market. The leadership team comprises experienced professionals in medical device innovation and commercialization, dedicated to delivering impactful solutions that offer both clinical and economic benefits to operating rooms worldwide.

Limax Biosciences transform tissue healing inside and outside the body.

Phagenesis Limited is focused on developing medical device technology aimed at treating dysphagia, a condition that impairs swallowing, often resulting from strokes or brain injuries. The company's primary product, Phagenyx, consists of a base station that delivers electrical stimulations to the patient and records pertinent information, along with a catheter that is introduced through the nose to stimulate the pharynx. This innovative approach leverages the brain's ability to relearn lost functions through neuroplasticity, effectively aiding patients in regaining control over their swallowing mechanisms. Founded in 2007 and based in Manchester, United Kingdom, Phagenesis emphasizes research and evidence-based solutions, with foundational work led by Professor Shaheen Hamdy of the University of Manchester, whose findings have been published in prestigious medical journals.

Discure Technologies is focused on creating a minimally invasive, implantable bioelectronic device aimed at treating degenerative disc disease (DDD). This innovative device employs a novel bioelectric technique that addresses the root cause of DDD, allowing physicians to alleviate pain and restore normal disc function in patients. By promoting healing of the affected discs, Discure seeks to improve the quality of life for individuals suffering from this condition.

RevBio is commercializing an injectable, self-setting bone adhesive that can bond bone to bone and bone to metal to stabilize implant devices. Over time, the adhesive biodegrades and is replaced by new bone. This unique material will reduce the duration and complexity of medical procedures, allow for more minimally invasive surgeries, and will improve patient outcomes by reducing recovery time and the overall cost of care.

Oxford Endovascular are developing a novel treatment for treating brain aneurysms. The Oxford technology uses a special laser-cut metal alloy which has a shape-memory. It can be posted into a catheter during surgery, inserted into the brain and opened up into a tiny tube mesh (‘flow diverter’) that fits into the natural shape of the blood vessel. This diverts the blood away from the aneurysm, allowing it to heal.

Neurovalens Limited is a company based in Ballymena, United Kingdom, that specializes in the development of medical devices grounded in neuroscience, bioscience, and neurophysiology. Founded in 2013, the company focuses on creating non-invasive neurostimulation products to address significant health challenges, particularly obesity. Notable products include Stimu Slim and Modius, which are electronic headsets designed to promote weight loss through transdermal activation of brainstem and hypothalamic functions. These devices aim to enhance autonomic function and circadian regulation, offering healthcare providers drug-free alternatives to improve patient health outcomes. Neurovalens has also received support from Invest NI as part of the European Union’s Investment for Growth and Jobs Programme, which will facilitate research and development to enhance the company's competitiveness.

ConKay Medical Systems is an early-stage medical device company focused on developing innovative solutions to address valvular regurgitation in patients suffering from progressive heart failure. The company's technology is centered around annular repair, which targets the primary cause of functional regurgitation while preserving the integrity of healthy leaflets. This approach aims to enhance the effectiveness of cardiovascular care, providing healthcare professionals with advanced tools to better manage this condition.

CloudMedx Inc. is a software development company based in Palo Alto, California, that specializes in artificial intelligence solutions for the healthcare sector. Founded in 2014, the company focuses on extracting key clinical concepts from electronic health records to provide actionable insights that enhance clinical operations, documentation, and patient care. Its platform transforms disparate healthcare data into a cohesive view that supports better clinical, treatment, and diagnostic outcomes. By integrating with existing systems, CloudMedx aims to facilitate collaboration among healthcare providers, payers, and patients. The company offers tools for patient engagement, risk stratification, and timely notifications for care needs, serving a diverse clientele that includes managed care organizations, accountable care organizations, and various healthcare facilities. The mission of CloudMedx is driven by a commitment to improve healthcare delivery, stemming from personal experiences related to misdiagnosis and the inefficiencies within the healthcare system.

Digma Medical is a clinical stage medical device company established in 2013, focused on innovating treatments for Type-2 Diabetes and related metabolic syndromes, including NASH. The company is developing the DiaGone™, an endoscopic and disposable device that employs advanced laser technology to treat the duodenum without the need for an implant. The Duodenal Glycemic Control™ procedure, which lasts approximately 30 minutes, allows gastroenterologists to use the DiaGone™ to enhance the body's ability to regulate glucose levels. This approach aims to offer patients the potential for long-term remission from Type-2 Diabetes and other metabolic conditions, thereby improving their overall quality of life and health outcomes. Supported by prominent venture capital firms, Digma Medical is dedicated to advancing effective therapies for diabetes management.

Woven Orthopedic Technologies is a medical device company based in Manchester, Connecticut, that specializes in developing orthopedic technologies aimed at improving patient care. Founded in 2013, the company focuses on enhancing the screw-to-bone interface to address challenges related to screw fixation in orthopedic procedures. Its innovative solutions utilize biopolymers and biotextile materials to increase surface area contact between screws and bone, thereby promoting bone healing and remodeling while enhancing fixation. The company aims to provide orthopedic surgeons with standardized, efficient, and accessible solutions that meet the diverse needs of patients. By addressing the most commonly used orthopedic implants, Woven Orthopedic Technologies strives to influence advancements in musculoskeletal care, ensuring that effective treatments are available to a wider population.

Tricog Health Services Pvt Limited, established in 2014 and headquartered in Bengaluru, India, specializes in cloud-connected ECG devices that facilitate the interpretation and analysis of electrocardiography (ECG) reports. The company addresses critical gaps in cardiac care, particularly in regions with limited access to diagnostic tools and trained personnel. Tricog's offerings include the InstaECG and VCardia applications, which enhance the speed and accuracy of cardiac monitoring. The company leverages artificial intelligence to provide real-time reporting and analysis of ECG results, enabling quicker diagnosis of cardiac events. This timely intervention is crucial, as survival rates for heart attack patients significantly improve with prompt treatment, yet many patients experience delays in diagnosis and care. Tricog Health aims to bridge these gaps, potentially saving millions of lives by ensuring that primary care clinics are equipped with affordable and efficient ECG solutions. With a presence in Singapore, Malaysia, and China, Tricog is positioned to expand its impact in the global healthcare landscape.

DermaSensor, Inc. develops a hand-held device that uses artificial intelligence to evaluate skin lesions for cancer. It offers DermaSensor, a device that allows physicians and consumers to perform skin checks in physician offices and patient homes. The company’s device is also used for lesion identification, scanning, photon scattering, and algorithmic analysis. DermaSensor, Inc. was founded in 2009 and is based in Miami, Florida.

SymPhysis Medical focuses on developing innovative medical technologies aimed at treating chronic diseases, with an emphasis on enhancing patient experience and quality of life. The company's flagship product, releaze, addresses malignant pleural effusion (MPE), a common complication in late-stage cancer patients that can lead to severe shortness of breath and chest pain. This therapeutic device is designed for home use, effectively draining excess fluid from the pleural space. By utilizing an active component that enhances fluid removal efficiency, releaze alleviates distressing symptoms and improves treatment accessibility for patients requiring indwelling pleural catheter (IPC) therapies.

SUTUREGARD Medical, Inc. is an Oregon-based company that develops, manufactures, and supplies innovative wound closure devices. Founded in 2014 and headquartered in Portland, the company offers products designed to enhance surgical outcomes. Its flagship device, SUTUREGARD ISR, facilitates stress-relaxation during wound healing, addressing issues such as skin stretch and reduced tension on surgical sites. Additionally, the HEMIGARD ARS serves as an adhesive retention suture device that reinforces skin strength, allowing for linear wound closure without the risk of skin ripping. By commercializing these advanced surgical products, SUTUREGARD Medical aims to simplify the wound closure process and improve patient recovery.

Fluid Biomed Inc. is a Calgary-based company that specializes in the development of innovative implantable vascular stents aimed at enhancing patient well-being. Established in 2012, the company focuses on creating a stent designed to gently divert blood flow away from brain aneurysms, facilitating their healing process. Through its commitment to innovation, Fluid Biomed seeks to improve health outcomes and overall quality of life for patients.

Corveus Medical is focused on creating innovative solutions to prevent heart failure through the development of a neuromodulation device. This catheter-based technology aims to safely and effectively access nerve tissue, enabling nerve ablation for improved treatment outcomes. By employing minimally invasive methods, Corveus Medical seeks to alleviate both the clinical and economic burdens associated with heart failure, marking a significant advancement in the field of cardiac care. The company is committed to delivering consistent results and enhancing patient quality of life through its pioneering approach to heart failure treatment.

Epineuron Technologies, Inc. is a medical device company based in Hamilton, Canada, focused on developing innovative treatment solutions for peripheral nerve injuries. Founded in 2016, Epineuron is pioneering bioelectronic medicine with a mission to set new standards in nerve repair and regeneration. The company is creating a range of surgical solutions, including an electroceutical device that provides electrical stimulation to enhance the natural healing processes of injured peripheral nerves. By accelerating nerve regeneration, Epineuron aims to offer patients advanced care options and aims to establish itself as a leader in the field of bioelectronic nerve therapy.

SafeBeat Rx replaces a hospitalization with a take-home kit that combines FDA-approved wearables with life-saving ECG software that expands access to proven heart therapies.

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EvoEndo is a medical technology company focused on advancing unsedated endoscopic procedures for both pediatric and adult patients. The company has developed a system that incorporates sterile, single-use flexible endoscopes, a virtual reality-based distraction method, and a comprehensive software integration platform. This innovative approach allows for routine endoscopies to be performed in a clinical setting without the need for general anesthesia or sedation. By streamlining the process, EvoEndo's technology aims to decrease complexity, lower costs, and alleviate the anxiety often associated with endoscopic procedures, making them more accessible and manageable for patients and healthcare providers alike.

Liquet Medical is a medical device development company focused on improving the treatment of vascular disease through innovative localized drug delivery methods. The company's flagship product, the Versus Catheter, features a dual-tip infusion design, real-time pressure monitoring, and a flow-directed placement balloon. These advancements aim to enhance patient outcomes and promote healthcare sustainability by providing healthcare professionals with more effective tools for managing vascular conditions. Liquet Medical's commitment to developing patented technologies positions it as a significant player in the medical device sector.

PyrAmes is a healthcare technology company focused on transforming the delivery of medical care through advanced sensor measurement. The company has developed a paper-thin, flexible device that enables non-invasive, continuous blood pressure monitoring. This ultra-low power device is designed to be accurate and wireless, making it suitable for patients across all age groups, from newborns to seniors. By providing a pain-free method for blood pressure monitoring, PyrAmes aims to enhance the quality of care offered by healthcare providers, particularly for vulnerable populations such as neonates.

Flosonics is a medical device company that focuses on developing non-invasive sensors to improve the management of critically ill patients. Flosonics's flagship smart-bandage product, the FloPatch, addresses unmet clinical needs of critically ill patients and the physicians, nurses, and paramedics who care for them in the ambulance, emergency department, operating room, and intensive care unit.

Forest Devices, Inc. is a medical device company based in Pittsburgh, Pennsylvania, with an additional office in Canada. Founded in 2014, the company focuses on developing innovative solutions for stroke detection. Its flagship product, AlphaStroke, is a non-invasive, AI-powered device designed for medical personnel to identify strokes in various environments, even before advanced imaging techniques like CT or MRI are available. This portable and durable device can detect both ischemic and hemorrhagic strokes, enabling practitioners to triage patients effectively and improve treatment outcomes. By streamlining the decision-making process in stroke management, AlphaStroke aims to reduce delays in critical care and enhance the overall frequency of stroke treatments.

ApiFix Ltd. is focused on developing a minimally invasive scoliosis deformity correction system specifically designed for adolescents suffering from Adolescent Idiopathic Scoliosis (AIS). Targeting patients categorized as Lenke Type 1 or Type 5 with a Cobb angle between 35 and 55 degrees, ApiFix's innovative approach differs from traditional scoliosis surgeries by allowing for gradual correction over several months, rather than a single invasive procedure. This system utilizes a miniature ratchet mechanism to facilitate incremental adjustments as the patient bends in the corrective direction, combined with specialized physical therapy to enhance outcomes. Founded in 2011 and based in Misgav, Israel, ApiFix operates as a subsidiary of OrthoPediatrics Corp. since April 2020.

OncoRes Medical Pty Ltd is an early-stage medical device company based in Nedlands, Australia, founded in 2014. The company specializes in developing a patented imaging technology that provides surgeons with real-time, micro-scale images of tissue stiffness and elasticity during breast cancer surgeries. This innovative tool integrates optical coherence tomography to enhance surgical accuracy, aiding in the differentiation between tumor and healthy tissue. OncoRes collaborates with leading researchers at the University of Western Australia and the Harry Perkins Institute of Medical Research, as well as breast cancer surgeons in the Western Australian public health system. With support from the Medical Research Commercialisation Fund, OncoRes Medical aims to improve clinical applications by enabling precise intraoperative assessments of tissue microstructure, ultimately striving to transform the standard of care in breast cancer treatment.

Bardy Diagnostics, Inc. is a medical device company that specializes in the development and manufacturing of cardiac monitoring solutions, primarily focused on arrhythmia detection. Its flagship product, the Carnation Ambulatory Monitor (CAM), is a lightweight, discreet cardiac patch that can be worn comfortably for up to seven days, even during physical activities like exercise or showering. The CAM is designed with a unique hourglass shape to enhance comfort, particularly for female patients. Complementing the monitor is the BDxCONNECT patient management system, which allows healthcare providers to create and manage patient reports efficiently. By utilizing innovative P-wave centric ECG detection technology, Bardy Diagnostics aims to improve clinical management and outcomes for patients and their physicians. Founded in 2013, the company is headquartered in Seattle, Washington, with additional offices in Houston, Texas, and New Providence, New Jersey.

Patchd Inc is a healthcare technology company based in San Francisco, California, founded in 2017. The company specializes in developing a wearable device designed to predict sepsis in outpatient settings. Its wireless patch continuously collects vital sign data, enabling healthcare providers to monitor patients effectively. By employing artificial intelligence algorithms, Patchd's technology facilitates the early detection of life-threatening conditions, particularly when used by hospitals for newly admitted patients. This innovative approach aims to enhance patient care and improve outcomes in post-acute care scenarios.

Pristine Surgical LLC, founded in 2011 and based in Manchester, New Hampshire, has developed a groundbreaking single-use digital imaging platform tailored for surgical and diagnostic rigid endoscopic procedures. The company specializes in single-use digital arthroscopes and laparoscopes that come in a completely sterile kit. By integrating high-definition digital imaging, advanced LED lighting, artificial intelligence, and cloud-based software, Pristine Surgical aims to enhance the efficiency and safety of over 23 million procedures annually. The platform not only improves the surgical experience for patients and healthcare providers but also addresses key concerns such as cost reduction, risk mitigation, and the elimination of cross-contamination associated with reprocessing instruments. Through its innovative technology, Pristine Surgical strives to streamline the entire surgical episode, ultimately improving communication and satisfaction among surgeons and healthcare facilities.

HD Medical Group Pty Ltd. designs and develops innovative medical products aimed at the screening and detection of cardiac conditions. The company's primary offerings include the ViScope, an electronic stethoscope featuring a visual display for auscultation, and the ViScope MD, which integrates a phonocardiogram visual display along with a murmur indicator. These products are distributed through various channels, enhancing accessibility for healthcare professionals. Founded in 2005 and headquartered in Melbourne, Australia, HD Medical also maintains additional offices in Sunnyvale, California; St. Leonards, Australia; and Chennai, India. The company is recognized as a global leader in the management of cardiovascular disease, focusing on enabling evidence-based patient diagnosis.

toSense is focused on rapidly bringing devices to the market that address real-world medical issues. toSense’s solutions include both hardware (custom sensors) and software (servers), along with wireless solutions (gateways) that connect these components. Our core focus is the CoVa Sensor and its unique hardware and algorithms. Third-party software systems can integrate with this novel component using our gateways and web services.

Starling Surgical is focused on advancing wound closure technology by developing innovative medical devices that enhance the efficiency and effectiveness of surgical sutures. The company manufactures surgical sutures and staplers designed to perform wound closures with the speed and convenience of a skin stapler, minimizing complications such as pain, infection, and unsightly scarring. By improving the wound closure process, Starling Surgical aims to facilitate better healing outcomes for patients following surgical procedures.

AltraTech Limited, established in 2013 and located in Shannon, Ireland, specializes in the design of biosensors and semiconductor chips aimed at DNA testing for food traceability in the agricultural sector. The company has developed a portable device that enhances molecular detection of viral DNA and RNA using advanced enrichment and semiconductor techniques. This innovation achieves the sensitivity and specificity comparable to traditional PCR methods, allowing for rapid and accurate measurement of viral samples. Through these technologies, AltraTech contributes to improving food safety and quality in the agri-business industry.

EPIC Neuro is focused on creating a small, leadless device designed for brain stimulation and cortical EEG recording to aid in stroke recovery. The device is powered externally through a headset or handheld module, making it simple to implant and eliminating the need for battery replacements. Its minimally invasive design ensures that it is inexpensive, easily removable, and safe for MRI procedures. This innovation aims to provide a hassle-free recovery experience for patients suffering from stroke symptoms.

Orbit Genomics applies its proprietary OrbiSeq technology platform to aid in diagnosing and ultimately preventing complex diseases.

Avelas BioSciences, Inc. is a clinical stage biotechnology company that focuses on developing technologies that advance care for cancer surgery and therapeutic intervention. It develops AVB-620, an intravenously administered in vivo fluorescent protease-activatable peptide that detects, marks, and diagnoses cancer. The company was incorporated in 2008 and is based in La Jolla, California.

Venari Medical Limited, founded in 2018 and based in Galway, Ireland, develops innovative medical devices aimed at treating chronic venous diseases (CVD). The company's flagship product, BioVena, employs the body's natural healing processes to provide a more effective and less invasive treatment option for conditions such as varicose veins and venous ulcers. Venari Medical seeks to address the significant gap in treatment, as only a small fraction of the 120 million individuals suffering from venous disease in the US and EU receive adequate care. Their technology not only offers a safer alternative to existing methods but also targets the underserved population of venous ulcer patients who currently rely on ineffective compression bandaging. By widening the indications for superficial venous ablation, Venari Medical aims to reduce the annual costs associated with venous ulcers, which total approximately $33 billion for insurers in these regions. The company's commitment to patient-centered solutions positions it to disrupt traditional treatment practices that have seen limited innovation in recent years.

ATRO Medical B.V., based in Nijmegen, the Netherlands, specializes in the development of an anatomically shaped polymer-based meniscus implant known as the Trammpolin. This innovative implant is designed to restore the protective function of the meniscus by acting as a spacer in the joint. ATRO Medical emerged as a spin-out from DSM and Radboudumc, leveraging expertise gained from a collaborative initiative that began in 2010, which included universities, private companies, and support from the Dutch government. The company combines clinical, biomechanical, and polymer knowledge to advance the Trammpolin design and its prototype development.

Previvo is a medical device company focused on preventing genetic diseases through its innovative technology that enhances pre-implantation genetic testing. By offering a more natural and healthier alternative to traditional in vitro fertilization and embryo collection methods, Previvo aims to empower women and couples undergoing assisted reproduction. Its patent-pending device is designed to facilitate pre-implantation genetic diagnosis and screening, helping to ensure healthier outcomes for prospective parents and their future children.

Forest Devices, Inc. is a medical device company based in Pittsburgh, Pennsylvania, with an additional office in Canada. Founded in 2014, the company focuses on developing innovative solutions for stroke detection. Its flagship product, AlphaStroke, is a non-invasive, AI-powered device designed for medical personnel to identify strokes in various environments, even before advanced imaging techniques like CT or MRI are available. This portable and durable device can detect both ischemic and hemorrhagic strokes, enabling practitioners to triage patients effectively and improve treatment outcomes. By streamlining the decision-making process in stroke management, AlphaStroke aims to reduce delays in critical care and enhance the overall frequency of stroke treatments.

CoapTech, Inc. is a medical device company based in Baltimore, Maryland, founded in 2016. It specializes in developing ultrasound-based solutions for feeding tube placement, primarily through its Point-of-care Ultrasound Magnet Aligned (PUMA-G) System. This innovative system enhances safety by using ultrasound visualization to guide the insertion of gastrostomy tubes, thereby eliminating risks associated with traditional methods such as PEG blind sticks, endoscope reprocessing, and fluoroscopy. CoapTech’s technology, known as Coaptive Ultrasound, utilizes strong rare-earth magnets for device placement and low-cost ultrasound for real-time visual feedback. This approach allows non-surgical providers to perform the percutaneous ultrasound gastrostomy (PUG) procedure efficiently and safely, improving patient care delivery while reducing healthcare costs. The company aims to disrupt multiple medical procedures by providing simpler, safer, and more affordable alternatives, focusing on enhancing access to quality medical services globally.

EndObetes is a medical device company that develops an endoscopically food delivery solution for treating obesity and diabetes. The company's device shunts food directly from the esophagus to the intestine, bypassing the stomach and duodenum, much like gastric bypass surgery, enabling people to get access to a durable, safe and effective non-surgical treatment for obesity and diabetes. It was founded in 2015 and is based in New York, New York.

CloudCath is a company that specializes in developing a remote monitoring platform for peritoneal dialysis patients. Their innovative system utilizes sensor-enabled technology to provide continuous monitoring, allowing for early detection of complications associated with catheter-based treatments. By leveraging Internet of Things (IoT) capabilities, CloudCath's platform enables healthcare providers to remotely oversee patients during their home treatment, significantly reducing the frequency of in-person visits. This approach not only enhances patient safety but also improves the overall management of care for individuals undergoing peritoneal dialysis, ultimately promoting better health outcomes.

Embolx, Inc. is a medical device manufacturer based in Sunnyvale, California, focused on creating catheter-based systems for cancer treatment. Founded in 2013, the company has developed innovative devices such as the Sniper, a drug delivery balloon microcatheter that enhances the precision of delivering therapeutic agents directly to tumors while minimizing the risk of affecting surrounding healthy tissues. Utilizing a technique known as Low Pressure Embolization (LPE), Embolx's devices regulate pressure to improve drug distribution within the tumor and eliminate non-target delivery. This technology aims to set a new standard in minimally invasive localized cancer therapy, while also addressing conditions such as benign prostatic hyperplasia and uterine fibroids.

Subtle Medical, Inc., a healthcare technology company, develops medical imaging software for clinical imaging centers and hospitals. Its product includes SubtleMR, an artificial intelligence-based image processing software that reduces image noise and increases image sharpness for non-contrast enhanced magnetic resonance imaging (MRI). It enables to reduce cost, imaging time, and radiation/contrast dose. The company was founded in 2017 and is based in Menlo Park, California.

Bone Health Technologies, Inc. is focused on creating innovative medical devices to combat low bone mass conditions such as osteopenia and osteoporosis. The company's flagship product, OsteoBoost, is a wearable device designed for the lower back that utilizes whole-body vibration technology to deliver gentle mechanical stimulation. This stimulation mimics the effects of weight-bearing exercise, promoting bone health by activating stem cells to strengthen bone density. Founded in 2018 and headquartered in San Francisco, California, Bone Health Technologies aims to provide a safe and effective non-drug intervention for individuals at risk of bone mass deterioration.

Soletics is a wearable technology company developing isothermal gloves to improve textiles service.

ThermopeutiX is a privately held company that offers imaginative, innovative and economical solutions to unmet medical needs.

ZKR Ortho is engaged in developing innovative medical devices and procedures aimed at alleviating chronic knee pain associated with Condromalacia Patellae, a condition characterized by the degeneration of cartilage and inflammation beneath the patella. This condition affects millions, often leading individuals to delay intervention due to the invasiveness of traditional surgical solutions. ZKR Ortho's approach offers a minimally invasive implant procedure that unloads the patellofemoral joint by elevating the patella tendon, thereby realigning the knee cap towards healthier cartilage. This method not only relieves pain but also promotes mobility and may reduce the necessity for knee replacement surgeries. Founded by Dr. Jeffrey Halbrecht, a leader in minimally invasive arthroscopic techniques, the company holds multiple patents and has developed prototypes for its devices. Currently, ZKR Ortho is in the process of raising capital to support product trials.

Respirix, Inc. is a medical technology company based in San Francisco, California, specializing in the development of precise analysis sensors for monitoring breath exhalation and cardiogenic oscillations. Founded in 2015, Respirix focuses on creating hardware and software solutions that provide insights into cardiac health, particularly through non-invasive monitoring of the pulmonary vasculature. Its product pipeline addresses various applications, including at-home monitoring and critical care, specifically targeting conditions such as heart failure and hemodynamics. The company's innovative approach integrates digital health tools to enhance the understanding and management of cardiac conditions.

Moving Analytics. is a tele-health company dedicated to helping people thrive after heart disease. Our flagship product is Movn a virtual cardiac rehabilitation program that leverages evidence based guidelines, behavioral science, remote monitoring and personalized coaching to help patients recover to full health after a cardiac event. Movn is currently used by the Veterans Affairs Medical Center, Highmark Health Plan, Kaiser Permanente Northwest and many more health systems across the US.

Olfactomics is a Finnish university-based spinoff company developing a novel technology for surgical tissue assessment. They focus on improving breast-concerving lumpectomies where residual tumor continues to be an issue. Realtime tissue analysis allows the surgeon to remove the whole tumor in one operation and minimize the resection of healthy tissues.

Koya Medical, Inc. is a company based in Oakland, California, founded in 2018. It focuses on developing a connected wearable platform designed to address the significant unmet needs in the treatment of cancer-related chronic lymphedema and venous diseases. The technology aims to provide a drug-free solution for patients suffering from these conditions, enhancing their quality of life through innovative medical devices.

Avisi Technologies Inc. is focused on developing innovative solutions to combat glaucoma, a leading cause of irreversible blindness. The company has created VisiPlate, a next-generation aqueous shunt designed for mid to late-stage glaucoma treatment. This product is notable for its ultrathin design, being 20 times thinner than a human hair, which facilitates a less invasive insertion procedure that reduces operating time and simplifies follow-up care. VisiPlate is constructed from alumina, a material recognized for its use in hip replacements, thus ensuring biocompatibility. Founded in 2017 and headquartered in Philadelphia, Pennsylvania, Avisi Technologies aims to address the challenges associated with current glaucoma treatments, including patient non-compliance and post-operative complications, ultimately striving to prevent blindness in affected individuals.

ClearCam Inc. is a medical technology company based in Austin, Texas, founded in 2018. The company specializes in manufacturing a laparoscopic lens cleaner device known as ClearCam Kelling, which is designed to enhance the visual field for surgeons during laparoscopic procedures. This innovative device allows for intra-operative lens cleaning without the need to remove the laparoscope from the body cavity, thereby streamlining surgical processes and improving safety. By eliminating the requirement for additional supplies, ClearCam's technology contributes to reduced procedure time, benefiting patients, surgeons, and surgical staff alike.

Evergaze, Inc. is a company based in Richardson, Texas, that focuses on developing innovative visual aids for individuals with macular degeneration. Established in 2016, Evergaze has created a unique device that consists of prescription glasses equipped with a monocular electronic vision augmentation system on one lens. The founding team comprises experienced engineers who have leveraged their expertise from various technical sectors to design this product. The seeBoost® device was developed through extensive collaboration with patients, practitioners, and researchers in the field of low vision, embodying a commitment to addressing the needs of those affected by visual impairments.

HEPTA Medical develops a sensor, embedded into a bronchoscopic or percutaneous ablation catheter, which provides temperature-based feedback. This enables real-time dosing to precisely target and ablates pulmonary nodules, the precursor of lung cancer, without the need for surgery or radiation.

Auctus Surgical is focused on innovative solutions for treating pediatric scoliosis through its dynamic vertebral body tethering system. This system is designed for non-fusion scoliosis correction, allowing for non-surgical adjustments over time. By incorporating dynamic magnetic technology, Auctus enables surgeons to implement a spinal tethering system that facilitates growth modulation without the need for traditional surgical interventions. In addition to its primary product, Auctus has also licensed technology related to magnetically adjustable growing rods, which can be utilized for both pediatric scoliosis treatment and limb lengthening. This approach aims to improve outcomes for young patients by providing a less invasive alternative to conventional surgical methods.

AMB Surgical is a developer of innovative medical devices aimed at treating pediatric deformities, particularly scoliosis. The company has created an electro-mechanical smart automated growing rod known as "FLYTE," which allows for precise and frequent non-surgical adjustments through sensor feedback. This technology enhances the capabilities of surgeons in managing complex cases involving pediatric scoliosis, dynamic external fixation for deformity correction, and applications related to long bone lengthening. By providing a solution that minimizes the need for invasive surgical procedures, AMB Surgical aims to improve treatment outcomes for children facing these conditions.

AblaCare is a Paris-based company founded in 2017 that focuses on addressing infertility related to Polycystic Ovary Syndrome (PCOS). The company has developed a minimally invasive procedure designed to restore ovulation in patients with PCOS, offering a more natural and less medicalized approach to pregnancy. This innovative treatment is performed transvaginally under ultrasound guidance, eliminating the need for general anesthesia. The procedure can be conducted in a clinic setting, utilizing techniques similar to those used by fertility specialists in in vitro fertilization (IVF). Through its solution, AblaCare aims to enhance the reproductive health and pregnancy experiences of women affected by PCOS.

Conavi Medical is a healthcare company focused on providing image guidance technologies for minimally invasive cardiovascular procedures.

Strados Labs, LLC is a medical technology company based in Philadelphia, Pennsylvania, that focuses on innovating respiratory health management through advanced biosensors and artificial intelligence. Founded in 2016, Strados Labs develops a wearable device that provides real-time insights into respiratory metrics such as breathing speed, sounds, and patterns. This device is equipped with a continuous breathing sensor that enables remote monitoring of patients with respiratory conditions like asthma and chronic obstructive pulmonary disease. By connecting the device to a mobile application, patients and healthcare providers can access critical respiratory data, facilitating informed decision-making and improved management of respiratory health.

Spire, Inc., also known as Spire Health, develops health-tracking devices and remote patient monitoring solutions aimed at managing respiratory chronic diseases. Founded in 2013 and based in San Francisco, the company specializes in continuous respiration sensing and offers ambulatory monitoring services. Its technology includes an activity tracker that monitors physical movement, breathing patterns, and sleep, providing insights into inhalation and exhalation times, apneic events, and daily activities. Spire Health's solutions cater to various health conditions, including chronic obstructive pulmonary disease, congestive heart failure, asthma, sleep disorders, and anxiety. By leveraging advanced algorithms and sensors, Spire Health aims to empower patients and healthcare providers with actionable data to improve health outcomes and overall well-being.

Medable, Inc. operates a cloud-based platform that facilitates decentralized clinical trials, enabling healthcare providers, biopharma sponsors, and clinical research organizations to enhance trial design, recruitment, retention, and data quality. The platform integrates various digital tools and services, ensuring compliance with health regulations while improving patient access and experience. Key offerings include solutions for telemedicine, such as HIPAA-compliant video consultations and platforms for capturing clinical trial outcomes remotely. Medable's services support the creation of applications for mobile, desktop, and web use, addressing the needs of doctors, hospitals, and health technology companies. Founded in 2015 and headquartered in Palo Alto, California, Medable has been utilized in clinical trials across over 30 countries and 26 languages, contributing to more effective therapy delivery and patient outcomes.

Deneb Medical is a start-up dedicated to developing a robotic platform for applications in neurosurgery, CMF surgery, head and neck surgery, urology and general surgery.

CroiValve Limited, founded in 2016 and based in Dublin, Ireland, specializes in the development of a medical device aimed at treating severe tricuspid regurgitation through a minimally invasive procedure. The company's innovative device allows for percutaneous delivery via a vein into the right heart, effectively sealing the gap between the native tricuspid valve leaflets. This approach restores proper valve function and prevents regurgitation, enabling healthcare professionals to address this condition in a safe, effective, and cost-efficient manner. CroiValve's solution is designed to be user-friendly, catering to a broad range of patients suffering from this serious heart issue.

Tasso, Inc. is a healthcare company based in Seattle, Washington, that specializes in the development of clinical-grade blood sample collection devices. Founded in 2012, Tasso has created innovative self-sampling devices that allow patients to collect their own blood at home with ease and convenience. These disposable devices are designed for user-friendliness, enabling individuals to obtain blood samples painlessly and securely. After collection, patients can mail the samples directly to qualified laboratories for analysis. Tasso's approach prioritizes patient comfort and privacy, fundamentally transforming the traditional blood collection process.

Deneb Medical is a start-up dedicated to developing a robotic platform for applications in neurosurgery, CMF surgery, head and neck surgery, urology and general surgery.

Paragate Medical is a company based in Nazareth Illit, Israel, specializing in the design and development of implantable devices aimed at providing continuous relief for patients suffering from congestive heart failure and fluid overload conditions related to heart and kidney failure. The company's innovative solutions address the clinical symptoms associated with these health issues, ultimately aiming to alleviate the associated healthcare burden for patients.

Darmiyan, Inc. is a company that specializes in the development of diagnostic software aimed at the early detection and monitoring of Alzheimer's disease and other neurodegenerative disorders. Based in San Francisco and founded in 2014, the company offers BrainSee, a Software as a Service platform that utilizes non-invasive brain MRI scans to produce detailed brain maps. This innovative tool quantifies neurodegeneration in individual brain voxels and generates a summary score reflecting brain health and the risk of cognitive decline. BrainSee operates using proprietary technology, referred to as The Virtual Microscope, which provides insights into brain cell distortion before clinical symptoms manifest. The algorithm has undergone successful third-party validation in the US and Canada, demonstrating its accuracy in predicting mild cognitive impairment. By leveraging advanced medical imaging and artificial intelligence, Darmiyan aims to enhance early diagnosis and intervention for patients with neurodegenerative diseases.

Colabs is a medical device manufacturing company that focuses on developing an emergency airway and ventilation system. Its device specializes in airway management and ventilation during cardiac arrest. The company was founded in 2012 and headquartered in St, Morgan Hill, California.

Ictero Medical is a medical devices company focused on developing innovative solutions for patients with gallstone disease. The company has created a minimally invasive gallbladder ablation tool that allows for the treatment of high-risk patients without the need for surgical removal of the gallbladder. This device can be utilized in interventional radiology suites and requires only minimal local anesthesia, thereby reducing the associated risks of traditional surgery. By offering a definitive treatment option, Ictero Medical aims to improve patient outcomes while minimizing complications related to gallbladder surgery.

Sana Health UK Limited develops a sleep mask for people with severe sleep problems caused by high anxiety or pain. The company offers Sana, a wearable device that allows the wearer to put themselves to sleep in 10 minutes. Its mask measures and tracks user’s overall state of health and vitality over time, and uses this measure to tailor the device to get user to deep relaxation and sleep fast. Sana Health UK Limited was founded in 2015 and is based in Dorchester, United Kingdom.

PercuSense is a development-stage company dedicated to advancing healthcare through innovative invasive medical devices that utilize physiological triggers for continuous monitoring. The company has developed a calibration-free electrochemical sensor capable of simultaneously measuring glucose, lactate, and oxygen levels. This technology provides patients with real-time and retrospective data on their metabolic health, facilitating better disease management and informed therapeutic decisions. By focusing on continuous multi-analyte monitoring, PercuSense aims to enhance patient outcomes and improve the overall understanding of metabolic health.