Khosla Ventures

Overture Life, Inc. is a biotechnology company based in New York, established in 2017, that specializes in developing robotic solutions for in vitro fertilization (IVF) applications. The company focuses on automating the IVF process through innovative medical devices and embryo testing methodologies, which enhance the efficiency and success rates of fertility treatments. By optimizing resource use and lowering costs, Overture Life aims to make IVF more accessible to a broader audience. Its technology includes automated cryopreservation and embryo testing services, enabling fertility clinics to identify viable embryos prior to implantation, thereby improving patient outcomes and supporting individuals in their journey to parenthood.

Mainspring Energy, Inc. is a technology company based in Menlo Park, California, that specializes in developing linear generator technology for low carbon, dispatchable energy solutions. Founded in 2010 by three Stanford engineers, the company focuses on creating advanced prototypes that convert fuel into electricity through a unique, low-temperature reaction of air and fuel. This innovative approach allows Mainspring to offer generators that provide affordable, reliable electricity while significantly reducing carbon emissions compared to traditional electric grids. The company's mission is to address climate change and enhance energy accessibility, contributing to the development of net-zero carbon energy systems for the future.

ReSource Chemical is a company based in Berkeley, California, focused on developing high-performance plastics derived from carbon dioxide. The company utilizes a proprietary bio-based platform to create chemicals that enable the production of environmentally friendly plastics with superior physical properties compared to traditional fossil fuel-based plastics. By converting CO2 into these innovative materials, ReSource Chemical aims to provide sustainable alternatives that do not contribute to environmental pollution.

Ramp offers a comprehensive financial operations platform designed for businesses seeking to streamline their financial tasks. The platform includes corporate cards, expense management, bill payments, and accounting integrations, assisting organizations in managing their finances efficiently.

Founded in 2022, Atomicwork is a San Francisco-based company specializing in modern service management software. Its platform integrates with popular tools like Microsoft Teams and Slack, enabling employees to resolve IT issues directly from these platforms without needing to access separate portals.

Rad AI develops an artificial intelligence platform that automates report generation for radiologists. Its solution integrates with existing workflows, automating repetitive tasks to enhance efficiency, reduce burnout, and improve patient care.

Clear Labs is a biotechnology company specializing in next-generation sequencing and data analytics for infectious disease surveillance and food safety testing. Its platforms, Clear Dx™ and Clear Safety™, enable rapid identification of pathogens, supporting public health initiatives and enhancing safety across various sectors.

LuxWall is a building materials company that designs and manufactures vacuum-insulated glass, a transparent insulation material that reduces heating and cooling losses and improves building energy efficiency. Its vacuum-insulated glass supports energy standards for commercial and residential buildings and uses technology aimed at enabling greater thermal performance. Founded in 2020 and headquartered in Ypsilanti, Michigan, LuxWall seeks to advance sustainable construction and has indicated a potential to reduce global carbon emissions by more than 0.5 gigatonnes per year, highlighting its environmental impact.

Mooncake Labs is building the modern lakehouse for every developer and application. We are an open source studio based in SF.

Paladin Drones Inc. is a technology company based in Berkeley, California, established in 2018. The company specializes in developing software that enhances the capabilities of drones to support first responders during emergencies. Upon receiving a 911 call, Paladin's software automatically dispatches a drone to the incident location, providing immediate situational awareness through a live video feed streamed back to the responders' application. This system simplifies the deployment process by managing various factors in the background, such as security, safety, weather conditions, and route planning, allowing emergency personnel to focus on their critical tasks.

Imprint is a financial services company founded in 2020 and based in New York, specializing in payments, rewards, and loyalty services. The firm has developed a full-stack payments and loyalty platform that facilitates payment processing for merchants and consumers. This platform allows users to execute financial transactions while also earning loyalty and reward points, streamlining the management of daily financial transactions. Imprint aims to enhance the payment experience by integrating rewards and loyalty features, making it easier for users to engage with their financial activities.

Inflammatix develops rapid molecular diagnostics tests that interpret the immune system to resolve major clinical challenges. Initially focused on acute bacterial and viral infections, sepsis, and other conditions like tropical infections and autoimmune diseases.

Viome Life Sciences, established in 2016 and headquartered in Bellevue, Washington, specializes in providing comprehensive health insights through its proprietary at-home clinical-grade tests. The company analyzes RNA from stool samples, along with other bodily fluids, to determine the makeup of microbial communities, offering personalized recommendations for diet and lifestyle based on the results. Viome's services aim to empower individuals to track their microbiome health, mitochondrial health, cellular health, and biological age, ultimately aiding in the prevention and reversal of chronic diseases. The company operates as a subsidiary of BlueDot LLC and sells its products through distributors and online channels.

PollyEx, Inc. operates a loan trading platform focused on the mortgage capital markets, facilitating transactions between buyers and sellers of mortgage loans. Founded in 2017 and based in San Francisco, California, PollyEx enhances loan sale execution through its cloud-based platform, which integrates with buyers and sellers via API, thereby increasing liquidity and automating various functions within capital markets. The platform aims to provide pricing transparency and improve operational efficiency for lenders, enabling them to make informed decisions throughout the lifecycle of a loan.

Egenesis is a biotechnology company focused on gene editing and genome engineering to develop human-compatible organs, tissues, and cells for transplantation. Its platform enables the creation of solid organs and therapeutic cells intended for transplantation, addressing the global organ shortage. The company pursues programs in kidney and islet cell transplantation and related regenerative approaches. It is based in Cambridge, Massachusetts, with an additional office in New York.

Openwater is a medical technology startup founded in 2016 and based in San Francisco, California. The company specializes in developing advanced wearable devices that utilize novel optoelectronics to achieve MRI-like resolution for medical diagnostics and treatments. By employing LCDs with small pixels, Openwater's technology creates holographic images that reduce scattering, enabling physicians to visualize the inner workings of the body and brain at a cellular level. This innovation allows for precise diagnosis and targeted treatment of diseases by manipulating or destroying individual cells without damaging surrounding tissue. Openwater aims to revolutionize medical imaging and improve patient outcomes through its cutting-edge approach.

Q Bio, Inc., established in 2015, develops a comprehensive health assessment platform that combines advanced non-invasive imaging, genetic testing, vital signs, and medical history to provide a snapshot of an individual's health. The company's flagship product, Q BioVault, aggregates and summarizes an individual's entire medical history, identifying and tracking significant health changes. Q Bio's interdisciplinary team, based in San Carlos, California, comprises experts in applied math, computational physics, electrical engineering, genetics, and radiology. Backed by prominent venture capital firms, the company aims to empower healthcare professionals with proactive, data-driven insights to improve patient outcomes.

WindBorne Systems designs, builds, and operates a network of long-duration high-altitude weather balloons equipped with sensors to collect atmospheric data for weather forecasting, climate research, and environmental monitoring. The company delivers its data to government and private weather services and has developed a balloon-based sensor delivery system alongside a weather forecasting platform that provides atmospheric data collection, AI-driven forecasts, insights, alerts, evaluations, and visualizations for decision-makers. By integrating data collection with advanced forecasting tools, WindBorne Systems supports more accurate forecasts, timely warnings for severe weather, and planning for climate adaptation.

PolyAI Ltd is a company that specializes in developing a conversational artificial intelligence platform aimed at enhancing human-machine voice interactions. Established in 2017 and headquartered in London, United Kingdom, with an additional office in New York, the company focuses on building enterprise voice assistants that engage in natural conversations with customers to address their needs. The platform utilizes advanced machine learning and natural language processing technologies, enabling it to understand and respond to customers effectively, regardless of the variations in their speech. Key features of PolyAI’s platform include multilingual support, dynamic flow design, and task-agnostic capabilities, allowing developers to create seamless and human-like interactions within various digital environments.

Glydways is a South San Francisco-based company specializing in affordable autonomous transportation systems. It designs, manufactures, installs, and operates efficient, high-capacity mobility solutions that are environmentally friendly with zero greenhouse gas emissions.

Rad AI develops an artificial intelligence platform that automates report generation for radiologists. Its solution integrates with existing workflows, automating repetitive tasks to enhance efficiency, reduce burnout, and improve patient care.

Karius is a life sciences company that develops genomic insights for infectious diseases. Its core offering, the Karius Test, is a non-invasive blood test that sequences microbial cell-free DNA to identify and quantify pathogens—including bacteria, DNA viruses, fungi, and parasites—for use in complicated pneumonia, infections in immunocompromised patients, and endocarditis. The company also provides laboratory services for pathogen biomarker detection for biopharmaceutical research and development. Founded in 2014, Karius is headquartered in Redwood City, California, with an additional office in Menlo Park, California. The laboratory operations are CLIA-certified and CAP-accredited, enabling high-complexity clinical testing. By mapping a patient’s microbial landscape from a single blood draw, Karius aims to support rapid, informed treatment decisions.

Rubedo Life Sciences, Inc. is a biopharmaceutical company based in Sunnyvale, California, focused on developing innovative therapies that target senescent cells implicated in age-related diseases. Established in 2018, the company utilizes its proprietary ALEMBIC drug discovery platform to create a pipeline of therapeutic candidates. These candidates are designed to selectively address senescent cells, as well as pro-inflammatory and pro-fibrotic cell populations that contribute to various chronic conditions, including pulmonary, dermatological, oncological, neurodegenerative, and fibrotic diseases. Rubedo's leadership team comprises industry experts with significant experience in drug development and commercialization across both large pharmaceutical companies and biotech firms.

Ramp offers a comprehensive financial operations platform designed for businesses seeking to streamline their financial tasks. The platform includes corporate cards, expense management, bill payments, and accounting integrations, assisting organizations in managing their finances efficiently.

Varda Space Industries, Inc. is a space manufacturing startup based in San Francisco, California, founded in 2020 by Delian Asparouhov and Trae Stephens. The company specializes in creating products in space that are intended for terrestrial applications, leveraging the unique advantages of low gravity. Varda aims to establish an infrastructure for harvesting materials from asteroids, enabling the production of new products in space. This approach not only facilitates the manufacturing of innovative goods but also promotes sustainability by reducing reliance on the destructive extraction of Earth's resources.

Skyflow, Inc. specializes in providing a privacy-focused application program interface solution that enables businesses to securely store and manage sensitive user information, including personally identifiable information (PII), payment card information (PCI), and protected health information (PHI). Founded in 2017 and based in Los Altos, California, Skyflow offers a cloud-native data privacy vault that employs advanced encryption and tokenization techniques to protect sensitive data across various applications. Its platform simplifies compliance with stringent regulations such as HIPAA, GDPR, and CCPA, ensuring that businesses can effectively govern and utilize their data while maintaining privacy standards. Formerly known as Prekari Labs, Inc., the company rebranded to Skyflow in December 2019.

Siolta Therapeutics, Inc. is a clinical-stage biotechnology company focused on developing microbiome-based therapeutics and diagnostics aimed at preventing and treating chronic inflammatory diseases, particularly asthma and atopic conditions. Founded in 2016 and headquartered in San Francisco, California, the company utilizes its extensive understanding of the developing gut microbiome to promote immune tolerance. Siolta Therapeutics is advancing pharmaceutical-grade anaerobic organisms and is currently in phase 2 of development for its products. By leveraging insights from human microbiome studies, the company aims to create targeted microbial therapeutics and companion diagnostics that facilitate precision medicine in the management of inflammatory diseases.

Encellin Inc., established in 2016, is a biotechnology company based in San Francisco, California. It specializes in developing innovative thin-film cell encapsulation devices for cell-based therapeutics, aiming to improve the lives of patients with chronic diseases initially focusing on Type 1 diabetes. The company's technology enables encapsulated cells to function as smart molecular factories, providing potential therapeutic solutions.

Founded in 2021, Kognitos is a San Jose-based company specializing in AI-driven business automation. Its platform leverages natural language processing to automate complex end-to-end processes across departments like finance, HR, and operations with minimal IT involvement.

Black Ore Technologies, established in 2022 and headquartered in Texas, USA, specializes in AI-driven financial services. The company's core product, Tax Autopilot, is an end-to-end automation solution for 1040 tax preparation, designed to streamline the process for Certified Public Accountants (CPAs) and tax firms. By leveraging artificial intelligence, Black Ore enables professionals to focus on client advisory services and practice growth.

Credit Genie is a fintech company that provides financial tools and debt relief services. It helps Americans take control of their finances, by offering no-fee-or-interest cash advances between paydays, tools to get out of debt, and insights into their spending habits.

Founded in 2015, Mojo Vision specializes in developing and commercializing advanced micro-LED display technology for various applications. The company is renowned for creating the world's smallest dynamic display for augmented reality smart contact lenses. Headquartered in Saratoga, California, Mojo Vision aims to disrupt the $160 billion display industry with its proprietary quantum-dot technology.

Glydways is a South San Francisco-based company specializing in affordable autonomous transportation systems. It designs, manufactures, installs, and operates efficient, high-capacity mobility solutions that are environmentally friendly with zero greenhouse gas emissions.

Founded in 2017, Mighty Buildings is a pioneering construction technology company based in San Francisco. It specializes in manufacturing custom houses using proprietary 3D printing techniques, aiming to revolutionize the residential housing market by reducing waste and enhancing energy efficiency.

Founded in 2016, Rejuvenation Technologies is a biotechnology company based in Mountain View, California. It specializes in developing nucleoside-modified TERT mRNA to safely extend telomeres for human health extension.

Reflex Robotics specializes in developing affordable humanoid robots, priced at around $10,000, to automate hazardous and repetitive tasks in logistics and manufacturing sectors. Their robots are designed and manufactured in-house by a team that previously led the development of the Stretch robot at Boston Dynamics and key components of Tesla's Model S, X, and Y production lines. The company's robotic technology is currently employed in beverage packing, warehouse palletizing, and shelf tote picking, aiming to streamline daily operations for various industries.

Viome Life Sciences, established in 2016 and headquartered in Bellevue, Washington, specializes in providing comprehensive health insights through its proprietary at-home clinical-grade tests. The company analyzes RNA from stool samples, along with other bodily fluids, to determine the makeup of microbial communities, offering personalized recommendations for diet and lifestyle based on the results. Viome's services aim to empower individuals to track their microbiome health, mitochondrial health, cellular health, and biological age, ultimately aiding in the prevention and reversal of chronic diseases. The company operates as a subsidiary of BlueDot LLC and sells its products through distributors and online channels.

Founded in 2019, Teamshares operates an online platform facilitating employee ownership in small businesses. It acquires traditional companies from retiring owners, transitioning them to be majority employee-owned within two decades. The company provides new leadership, financial education, equity management software, and financial products to support this process.

Caelux is a renewable energy company based in Pasadena, California, founded in 2014. It specializes in developing and manufacturing perovskite-on-glass technology for the terrestrial solar and commercial space industries. This innovative technology is designed to enhance solar device efficiency while minimizing the amount of semiconducting material required, thereby reducing production costs. Caelux's products improve power production and integrate seamlessly into existing photovoltaic module manufacturing processes, allowing users to lower installed costs and boost overall performance.

WindBorne Systems designs, builds, and operates a network of long-duration high-altitude weather balloons equipped with sensors to collect atmospheric data for weather forecasting, climate research, and environmental monitoring. The company delivers its data to government and private weather services and has developed a balloon-based sensor delivery system alongside a weather forecasting platform that provides atmospheric data collection, AI-driven forecasts, insights, alerts, evaluations, and visualizations for decision-makers. By integrating data collection with advanced forecasting tools, WindBorne Systems supports more accurate forecasts, timely warnings for severe weather, and planning for climate adaptation.

Founded in 2017, TeraWatt Technology designs and manufactures lithium-ion rechargeable batteries for various electrified applications. The company is headquartered in Santa Clara, California with a subsidiary in Tokyo, Japan.

Credit Genie is a fintech company that provides financial tools and debt relief services. It helps Americans take control of their finances, by offering no-fee-or-interest cash advances between paydays, tools to get out of debt, and insights into their spending habits.

Replit is a browser-based integrated development environment (IDE) founded in 2016. It enables collaborative coding across platforms using over 50 programming languages. Users can build apps and websites, share projects, create communal workspaces, and execute code via containers, all within a browser on any operating system.

Lexion is a Seattle-based company that specializes in developing a software-as-a-service application for contract management. Utilizing artificial intelligence and natural language processing, Lexion's system automatically reads, interprets, and organizes corporate contracts, identifying key terms such as termination notices, renewal dates, and payment obligations. The platform consolidates all contracts into a unified hub, allowing businesses to gain insights and effectively manage their legal documents. By integrating various business, storage, and signature systems, Lexion enables companies to streamline their contract processes, saving time and reducing costs while ensuring that critical contract obligations are automatically tracked and maintained.

Gather Health is an international healthcare technology company dedicated to empowering chronic disease patients to enhance their health. The company develops mobile and cloud-based healthcare applications that utilize cutting-edge medical and behavioral research to motivate and educate patients. By connecting physicians, patients, their families, and communities, Gather Health aims to provide continuous and holistic care that leads to improved health outcomes. The rise in chronic diseases such as obesity, diabetes, and hypertension has created a pressing need for effective patient care solutions, especially given the shortage of healthcare providers. Gather Health's flagship product, the Gather Health Diabetes platform, is currently utilized by physicians and patients in various cities across Hong Kong and India, including Mumbai and Bangalore, demonstrating positive health outcomes for users. Headquartered in Hong Kong, with additional offices in Beijing, New York, and India, the company boasts a diverse team of clinicians, health experts, interaction designers, and engineers experienced in the global healthcare landscape.

Founded in 2015, Mojo Vision specializes in developing and commercializing advanced micro-LED display technology for various applications. The company is renowned for creating the world's smallest dynamic display for augmented reality smart contact lenses. Headquartered in Saratoga, California, Mojo Vision aims to disrupt the $160 billion display industry with its proprietary quantum-dot technology.

Quell, Inc., founded in 2020 and based in San Francisco, California, specializes in developing an immersive fitness game that combines exercise with interactive gameplay. The company's product includes a low-cost wearable device featuring smart resistance bands, which guides users through engaging combat workouts at home. Quell's unique approach to fitness allows players to achieve their fitness goals while enjoying an intense workout within a virtual fantasy world. The startup charges a monthly fee to provide fresh content, positioning itself as a blend of Peloton and gaming experiences.

Light Field Lab, Inc. is a technology company specializing in the development of holographic display systems that create immersive visuals by projecting three-dimensional holograms into physical space. Founded in 2017 and based in San Jose, California, the company leverages advanced light field technology to generate multiple viewing angles that mimic real-world perceptions, allowing objects to appear to float in space without the need for head-mounted displays. Light Field Lab's innovations enable new opportunities in both consumer and enterprise markets, facilitating the integration of existing content into their holographic formats through a universal application programming interface. The company's mission is to pioneer a holographic future, advancing how visual media is experienced across various applications.

Visible is a Miami-based company founded in 2022 that aims to transform real estate transactions through modern technology. By developing a financial network, Visible seeks to empower smaller-scale real estate investors by providing them with access to essential data, legal frameworks, and capital. The company's goal is to create a more equitable environment for buying, selling, and monetizing property, enhancing the traditional title system to facilitate these processes for homeowners and investors alike.

LuxWall is a building materials company that designs and manufactures vacuum-insulated glass, a transparent insulation material that reduces heating and cooling losses and improves building energy efficiency. Its vacuum-insulated glass supports energy standards for commercial and residential buildings and uses technology aimed at enabling greater thermal performance. Founded in 2020 and headquartered in Ypsilanti, Michigan, LuxWall seeks to advance sustainable construction and has indicated a potential to reduce global carbon emissions by more than 0.5 gigatonnes per year, highlighting its environmental impact.

Founded in 2016, Bionaut Labs specializes in developing intra-tissue navigation platforms using micro-robots for precise anatomical targeting. Its innovative technology enables remote-controlled delivery of therapeutics to challenging clinical settings, revolutionizing the treatment of central nervous system disorders and other diseases.

Viome Life Sciences, established in 2016 and headquartered in Bellevue, Washington, specializes in providing comprehensive health insights through its proprietary at-home clinical-grade tests. The company analyzes RNA from stool samples, along with other bodily fluids, to determine the makeup of microbial communities, offering personalized recommendations for diet and lifestyle based on the results. Viome's services aim to empower individuals to track their microbiome health, mitochondrial health, cellular health, and biological age, ultimately aiding in the prevention and reversal of chronic diseases. The company operates as a subsidiary of BlueDot LLC and sells its products through distributors and online channels.

Equii is a food technology company that discovers nutritious microbial proteins from various sources. These are used to ferment grains, resulting in high-protein grain flours.

Mainspring Energy, Inc. is a technology company based in Menlo Park, California, that specializes in developing linear generator technology for low carbon, dispatchable energy solutions. Founded in 2010 by three Stanford engineers, the company focuses on creating advanced prototypes that convert fuel into electricity through a unique, low-temperature reaction of air and fuel. This innovative approach allows Mainspring to offer generators that provide affordable, reliable electricity while significantly reducing carbon emissions compared to traditional electric grids. The company's mission is to address climate change and enhance energy accessibility, contributing to the development of net-zero carbon energy systems for the future.

PolyAI Ltd is a company that specializes in developing a conversational artificial intelligence platform aimed at enhancing human-machine voice interactions. Established in 2017 and headquartered in London, United Kingdom, with an additional office in New York, the company focuses on building enterprise voice assistants that engage in natural conversations with customers to address their needs. The platform utilizes advanced machine learning and natural language processing technologies, enabling it to understand and respond to customers effectively, regardless of the variations in their speech. Key features of PolyAI’s platform include multilingual support, dynamic flow design, and task-agnostic capabilities, allowing developers to create seamless and human-like interactions within various digital environments.

AliveCor, Inc. specializes in developing digital medical-grade electrocardiograms, enabling users to monitor their heart health through mobile technology. The company's flagship product, KardiaMobile, is a personal mobile EKG device that provides instant detection of common heart arrhythmias, along with features for blood pressure and weight tracking, as well as storage for recorded EKGs. Additionally, AliveCor offers KardiaMobile 6L, a six-lead EKG device that allows patients to share detailed EKG readings with healthcare providers. The company also operates KardiaCare, a digital health subscription service that empowers users to manage their heart health conveniently at home. Founded in 2010 and incorporated in 2011, AliveCor is headquartered in Mountain View, California, and is recognized for its innovative contributions to cardiac care through the integration of machine learning techniques.

Prellis Biologics is a biotechnology company based in San Francisco, founded in 2016, focused on bioprinting vascularized human tissues and organs for drug development, disease modeling, and transplantation. Its platform enables rapid, high-resolution printing of tissues and organoids, including lymph node models, to reproduce human immune responses. This capability supports antibody discovery, immunogenicity assessment, and tumor–immune studies, aiming to accelerate early-stage drug discovery and translational pharmacology while advancing the development of tissue and organ therapies.

Aisera, Inc. is a technology company based in Palo Alto, California, that specializes in artificial intelligence solutions aimed at automating tasks and workflows for enterprises and consumers. Established in 2017, Aisera offers a range of products including AI Service Desk and AI Customer Service, which cater to various functions such as IT, human resources, sales, and operations. The company’s AI Experience platform combines generative AI capabilities with domain-specific large language models to create customizable solutions that enhance user interactions and improve productivity. Aisera's technology facilitates auto-resolution of service issues and streamlines business processes, resulting in significant cost savings and increased efficiency for organizations across multiple sectors, including healthcare, finance, and retail. Recognized for its innovation, Aisera continues to lead in service automation through its advanced AI-driven offerings.

Lead Bank is a commercial bank based in Garden City, Missouri, established in 1928. It provides a comprehensive range of banking and financial services aimed at promoting economic growth for businesses. The bank offers business accounts, cash management, credit card services, and business loans, along with online and mobile banking options. Additionally, Lead Bank specializes in transaction and financial advisory services, including interim executive placements, financial and strategic planning, mergers and acquisitions advisory, private equity placements, capital sourcing, and business valuations. Through its division, Lead Business Advisors, the bank also delivers advisory services that encompass bookkeeping and business brokerage.

Founded in 2017, TeraWatt Technology designs and manufactures lithium-ion rechargeable batteries for various electrified applications. The company is headquartered in Santa Clara, California with a subsidiary in Tokyo, Japan.

Ultima Genomics is a biotechnology company established in 2016 and headquartered in Newark, California. It specializes in genome-scale sequencing technology, focusing on providing analytical services to various enterprises. By employing an open substrate, Ultima Genomics creates a vast, low-cost reaction surface that facilitates billions of reads without relying on expensive flow cells or complex fluidic systems. The company utilizes specialized sequencing hardware combined with machine learning techniques to ensure reproducible and accurate results. This innovative approach enables clients to obtain genomic reports at scale, enhancing the speed and efficiency of sequencing while significantly reducing costs. Ultima Genomics aims to harness the potential of genomic information to drive advancements in biology and improve human health.

Mainspring Energy, Inc. is a technology company based in Menlo Park, California, that specializes in developing linear generator technology for low carbon, dispatchable energy solutions. Founded in 2010 by three Stanford engineers, the company focuses on creating advanced prototypes that convert fuel into electricity through a unique, low-temperature reaction of air and fuel. This innovative approach allows Mainspring to offer generators that provide affordable, reliable electricity while significantly reducing carbon emissions compared to traditional electric grids. The company's mission is to address climate change and enhance energy accessibility, contributing to the development of net-zero carbon energy systems for the future.

Mirvie is a biotechnology company specializing in precise, non-invasive diagnostic tests for maternal-fetal health. Founded in 2018, the company aims to enhance pregnancy safety by providing actionable insights to families and enabling early intervention for potential complications.

Bubbles is a contextual collaboration tool that enables users to communicate asynchronously by tagging content directly on their screens. The platform facilitates discussions in-context through screen, video, and audio messages, allowing team members to capture, comment, and share information without the need for account creation or installation. Bubbles promotes organic growth and viral engagement rather than relying on paid advertising. It is actively engaged on various social media platforms, including Medium, Twitter, and Product Hunt, to enhance its visibility and user interaction.

Adyton PBC specializes in designing and developing cloud-based software solutions for reporting, data maintenance, and scheduling. The company offers products such as AKADEMIA, which provides real-time reporting and analytics along with training data recording and management, and Smart Schedule, a software designed for managing training, qualifications, and daily operations. Additionally, Adyton PBC has created the Adyton Operations Kit (AOK), a secure mobile software tailored for mission-critical tasks, particularly suited for defense and emergency response applications. Founded in 2018 and headquartered in Wilmington, Delaware, Adyton PBC serves a diverse range of industries, including defense, heavy industries, law enforcement, and emergency responders.

VitroLabs specializes in 3D tissue engineering, focusing on the development of real leather using stem cell-based technologies. Founded in 2016 and based in San Jose, California, the company aims to create luxury quality lab-grown leather with a low carbon footprint, thereby reducing harm to animals.

Primer is a San Francisco-based company that operates an online platform focused on providing customized educational experiences for students at home. Through its Primer Microschools, the company emphasizes personalized learning, allowing students to progress at their own pace while pursuing their individual interests. The platform is designed to support learners by fostering an environment conducive to personal growth and development, positioning itself as a forward-thinking educational solution for the leaders of tomorrow.

Enso is a creative impact agency founded in 2012 and headquartered in Santa Monica, California. The company leverages strategic, creative, and community-building skills to create positive change for the planet and individuals. It focuses on developing innovative ideas that challenge the status quo and have the potential for widespread scalability by fostering collaboration among brands, organizations, and individuals around shared missions. Additionally, Enso offers tools that enable rapid software creation, allowing business leaders, analysts, data scientists, and developers to collaboratively design workflows and enhance communication. Through its multifaceted approach, Enso aims to drive forward-thinking solutions that contribute to a better future.

Founded in 2014, Ellevest is an employee-owned investment firm dedicated to empowering women financially. It offers a user-friendly digital platform that provides personalized investment plans tailored to women's unique financial needs and goals.

Tarana Wireless, Inc. is a technology company that specializes in researching, developing, and commercializing non-line-of-sight (NLoS) wireless transport solutions. Its flagship product, AbsoluteAir 2, offers advanced wireless transport capabilities with features such as deterministic True NLOS performance, extensive coverage, multi-kilometer range, and high spectral efficiency. The company provides construction-grade installation services and a carrier-class management system that allows operators to configure, monitor, and manage their network nodes effectively. Tarana's solutions are designed to support various applications, including small-cell backhaul, wireless fiber extension, and fixed wireless broadband access. The company serves tier-1 telecommunications operators globally and is headquartered in Milpitas, California, with additional offices in Berkeley, California, and Pune, India. Tarana Wireless was established in 2009 and has made significant advancements in wireless technology, offering lower total cost of ownership and unmatched scalability for its clients.

Hermeus Corporation, founded in 2018 and based in Atlanta, Georgia, is focused on developing hypersonic aircraft capable of flying at speeds exceeding Mach 5. These advanced jets significantly reduce travel times, allowing a flight from New York to London to take just 90 minutes instead of the typical seven hours. Hermeus aims to enhance the global transportation network by enabling businesses to operate efficiently without major changes to existing aviation infrastructure. The company's innovations not only decrease flight durations but also enhance safety for long-haul and business class air travel, facilitating improved connectivity between major global cities.

Roofstock operates an online marketplace enabling investors to buy and sell single-family rental homes with existing tenants. Founded in 2015, the company provides research tools, analytics, and insights to facilitate informed investment decisions.

Volta Labs, Inc. is a biotechnology company based in Cambridge, Massachusetts, founded in 2018. The company specializes in engineering and developing innovative tools for biological automation, focusing on scalable automation solutions for genetic engineering. Its platform is designed to revolutionize genomics research by providing affordable genomic sample preparation and automation for complex biological workflows. By integrating expertise from engineering, surface chemistry, and molecular biology, Volta Labs aims to streamline sample processing and enhance the capabilities of biotech organizations in the next generation of genomic automation.

Emi Labs is a technology company that develops AI-powered recruitment software to transform the hiring process for firms with high-volume openings. Its flagship AI recruitment assistant engages applicants in natural conversations to identify qualified candidates while automating screening, skills validation, interview scheduling and document collection, thereby shortening hiring cycles and boosting recruiter productivity. The platform aims to improve the candidate experience and enable scalable, personalized engagement. The company operates a remote-first model with office hubs in Buenos Aires, Mexico City, and San Francisco.

Scipher Medicine develops a molecular technology platform that predicts patient responsiveness to specific drugs in cardiovascular and autoimmune diseases. Its flagship product, PrismRA, identifies rheumatoid arthritis patients unlikely to respond to anti-TNF therapies, enabling alternative treatments. The company aims to transform drug prescription by predicting optimal therapy using simple blood samples.

Academia.edu is the largest and fastest-growing platform in the world for sharing academic research. Its mission is to accelerate and democratize academic research. Over 150 million academics have signed up to Academia.edu, adding 25 million papers. Over 100,000 people join Academia.edu each day. Academia.edu attracts over 52 million unique visitors a month. 40% of the world's faculty log in to Academia.edu every month. The company was founded in 2008 and is headquartered in San Francisco, California.

Founded in 2017, WorkWhile is a technology platform that connects skilled hourly laborers with job shifts across industries such as warehousing, light industrial work, delivery services, hospitality, food production, and event management. The platform uses cognitive science and behavioral analysis to match workers' skills, schedules, and locations with suitable jobs. It offers benefits like next-day pay and sick leave credits for its workforce.

Helium Systems Inc. develops Internet-of-Things (IoT) technology, focusing on sensor devices that monitor environmental factors such as temperature, humidity, barometric pressure, motion, and light. These sensors are utilized in various applications, including facility monitoring and quality control for medical products, energy management, air quality assessment, and refrigeration temperature regulation. The company offers a web and mobile dashboard for users to manage and access sensor data. Additionally, Helium operates a decentralized wireless network that enables low-power IoT devices to connect to the internet. This network incentivizes individuals to become network operators, rewarding them with a cryptocurrency for validating network transactions and contributing to the network's integrity. Incorporated in 2013 and based in San Francisco, Helium Systems continues to innovate within the IoT landscape, enhancing the ability to gather insights from smart devices.

Homebound is a tech-enabled custom homebuilder that manages the entire construction process for homeowners, from insurance negotiations and architecture to permitting, construction and move-in. Born out of the 2017 Northern California wildfires and based in Santa Rosa, California, the company focuses on rebuilding homes after disasters and uses technology and a network of vetted building professionals to simplify the process and support homeowners at every step.

Verdagy specializes in innovative water electrolysis technology for large-scale green hydrogen production. Based in Moss Landing, California, the company operates laboratory and pilot plant facilities to advance its technology platform, aiming to achieve low upfront capital costs and competitive unit economics.

LEX Markets Corp., established in 2018 and based in New York, operates an online platform for trading shares of individual commercial real estate assets. It facilitates both accredited and non-accredited investors to buy and sell shares, with investments starting at $250 and no lockup periods. The company specializes in taking commercial buildings public through single-asset IPOs, making it possible for a broader range of investors to access the real estate market. LEX Markets' platform is powered by Nasdaq technology, ensuring robust, low latency, and high-performance trading features.

PollyEx, Inc. operates a loan trading platform focused on the mortgage capital markets, facilitating transactions between buyers and sellers of mortgage loans. Founded in 2017 and based in San Francisco, California, PollyEx enhances loan sale execution through its cloud-based platform, which integrates with buyers and sellers via API, thereby increasing liquidity and automating various functions within capital markets. The platform aims to provide pricing transparency and improve operational efficiency for lenders, enabling them to make informed decisions throughout the lifecycle of a loan.

Culdesac Inc. is a real estate development company based in San Francisco, California, focused on creating car-free residential neighborhoods in the United States. Established in 2018, the company's first project is in Tempe, Arizona, where it aims to build the first car-free neighborhood from scratch in the country. This innovative approach prioritizes pedestrian accessibility and eco-friendly living by eliminating parking spaces for residents while providing designated areas for visitors. The neighborhood will feature essential services such as grocery stores, coffee shops, coworking spaces, and market halls, allowing residents to engage with their community directly from their doorsteps. Culdesac's vision is to reimagine urban living by putting people before cars, fostering a sustainable and vibrant lifestyle.

Founded in 2018, Azibo is a financial services platform dedicated to streamlining rental property management. It offers solutions for rent collection, banking, lending, and insurance, aiming to improve efficiency and reduce administrative burden for small real estate owners.

Prellis Biologics is a biotechnology company based in San Francisco, founded in 2016, focused on bioprinting vascularized human tissues and organs for drug development, disease modeling, and transplantation. Its platform enables rapid, high-resolution printing of tissues and organoids, including lymph node models, to reproduce human immune responses. This capability supports antibody discovery, immunogenicity assessment, and tumor–immune studies, aiming to accelerate early-stage drug discovery and translational pharmacology while advancing the development of tissue and organ therapies.

Robin Healthcare, Inc. is a healthcare technology company founded in 2017 and headquartered in Berkeley, California, with an additional office in Austin, Texas. The company specializes in developing innovative solutions for the medical industry, including a smart assistant device, clinical documentation solutions, and services for order and medication entry, chart review, billing and coding, and referral management. Robin Healthcare provides comprehensive medical scribe services designed to alleviate administrative burdens on healthcare providers, thereby enhancing the doctor-patient experience. By integrating technology and trained medical scribes directly into electronic medical records, the company aims to streamline workflows and allow physicians to focus more on patient care.

CloudTrucks is a San Francisco-based company founded in 2019 that offers a virtual trucking carrier platform designed to help truck owners and operators reduce operating costs by managing and booking loads from brokers and shippers. The platform provides instant payments after load delivery and access to affordable insurance options, enabling users to plan their schedules and design a revenue-maximizing driving program.

Founded in 2013, Fundbox operates a payments network that facilitates transactions between businesses. It provides credit and payment solutions to small businesses serving other businesses (SMB2B), empowering them with fast and intuitive access to business credit.

Up&Up is a New York-based real estate company founded in 2017 that offers a platform for fractional homeownership. This innovative approach allows renters to invest in their homes upfront, enabling them to benefit from home price appreciation while building equity through portions of their rent payments. By making every resident a part-owner of their chosen home, Up&Up provides a more accessible and flexible alternative to traditional rental models. The company aims to enhance the rental experience by offering financial benefits typically associated with homeownership, while also preserving the convenience and ease of renting.

Founded in 2018, Fountain Therapeutics develops cellular model-based therapeutics targeting age-related diseases. It employs an AI-driven platform for identifying novel targets and potential treatments.

Founded in 2015, Heyday operates a digital marketplace platform designed to accelerate consumer product brands. Headquartered in San Francisco with a presence in New York, the company specializes in data-driven strategies to drive revenue growth for partnered eCommerce businesses.

Faire is a two-sided marketplace connecting local retail stores with unique wholesale merchandise from brands and makers. It offers retailers tools for data insights, financial terms, and logistics support to compete with larger competitors. Faire's platform simplifies wholesale buying and selling processes, offering net 60 payment terms and free returns.

ThoughtSpot provides an AI-native intelligence platform that empowers enterprises to explore any data, ask questions, and uncover actionable insights. It offers intuitive natural language search, enabling users to generate answers from business data at every point of decision-making. ThoughtSpot serves various industries, with clients including NVIDIA, Hilton Worldwide, Capital One, and Huel.

Viome Life Sciences, established in 2016 and headquartered in Bellevue, Washington, specializes in providing comprehensive health insights through its proprietary at-home clinical-grade tests. The company analyzes RNA from stool samples, along with other bodily fluids, to determine the makeup of microbial communities, offering personalized recommendations for diet and lifestyle based on the results. Viome's services aim to empower individuals to track their microbiome health, mitochondrial health, cellular health, and biological age, ultimately aiding in the prevention and reversal of chronic diseases. The company operates as a subsidiary of BlueDot LLC and sells its products through distributors and online channels.

Enso is a creative impact agency founded in 2012 and headquartered in Santa Monica, California. The company leverages strategic, creative, and community-building skills to create positive change for the planet and individuals. It focuses on developing innovative ideas that challenge the status quo and have the potential for widespread scalability by fostering collaboration among brands, organizations, and individuals around shared missions. Additionally, Enso offers tools that enable rapid software creation, allowing business leaders, analysts, data scientists, and developers to collaboratively design workflows and enhance communication. Through its multifaceted approach, Enso aims to drive forward-thinking solutions that contribute to a better future.

Velo3D specializes in metal laser sintering 3D printing technology for industrial applications. It offers the Sapphire Printer system, Flow software for print preparation, and Assure for quality assurance. Serving contract manufacturing, aviation/aerospace, energy, and industrial sectors, Velo3D enables support-free metal printing.

VitroLabs specializes in 3D tissue engineering, focusing on the development of real leather using stem cell-based technologies. Founded in 2016 and based in San Jose, California, the company aims to create luxury quality lab-grown leather with a low carbon footprint, thereby reducing harm to animals.

Vicarious Surgical Inc. is a robotics company based in Charlestown, Massachusetts, established in 2014. The company specializes in developing advanced technologies for minimally invasive surgical procedures, focusing on enhancing surgical efficiency, improving patient outcomes, and reducing healthcare costs. Its flagship product, the Vicarious Surgical Robotic System, integrates virtual reality software with human-like robotic capabilities, enabling surgeons to perform complex surgeries with greater precision and control. Designed for abdominal access through a single port, the system is compact and portable, facilitating easy integration into existing operating rooms. By minimizing invasiveness, Vicarious Surgical aims to accelerate patient recovery times and decrease post-operative discomfort, thereby transforming the landscape of surgical care.

StateSpace provides performance analytics and a suite of tools for casual gamers and esports athletes to maximize their potential. It uses cognitive science and artificial intelligence to revolutionize the way humans improve. Leveraging expertise as neuroscientists, data scientists, video game developers, and computer visionaries, the products bring much needed standardized performance analytics to train.It was founded in 2017 and is headquartered in New York, New York.

Juno Residential, Inc. is a company focused on the development of residential apartments, incorporating innovative construction methods to provide environmentally friendly housing solutions. Based in San Francisco, California, Juno specializes in prefabricated houses, utilizing techniques that emphasize speed and efficiency. The company is committed to sustainability, employing organic and low-carbon materials, such as mass timber, in its projects. By offering modern and curated living spaces, Juno aims to address the growing demand for sustainable housing alternatives in urban environments. Founded in 2018, Juno Residential, Inc. was previously known as Lighthouse Residential, Inc.