ViroCell Biologics
Convertible Note in 2024
ViroCell Biologics is a contract development and manufacturing organization (CDMO) specializing in the production of viral vectors and gene-modified cells. The company focuses on facilitating the advancement of novel cell and gene therapies into clinical trials. By providing a platform that ensures a rapid, safe, and reliable transition from laboratory research to clinical application, ViroCell Biologics aims to de-risk and enhance the value of cell and gene therapy innovations. This enables medical researchers to obtain the necessary gene-modified cells for their clinical studies, supporting the development of new treatments in the field of regenerative medicine.
TheWell Bioscience
Corporate Round in 2024
TheWell Bioscience is a biotechnology company specializing in 3D cell culture technology designed to enhance life science research. It provides a novel hydrogel system that supports scientists and researchers in drug screening, tissue engineering, and pre-clinical applications. By bridging the gap between traditional in vitro studies and in vivo models, TheWell Bioscience enables more robust analysis platforms that contribute to drug discovery and personalized medicine. Its innovative approach aims to improve the efficiency and effectiveness of research methodologies within the healthcare industry.
SPARTA Biodiscovery
Seed Round in 2023
Sparta Biodiscovery specializes in providing analytical testing services for nanoparticles used in pharmaceutical and biotechnology industries. The company facilitates nanoformulations for upcoming therapies, offering simultaneous size and chemical compositional analysis on a single-particle basis, catering to diagnostic and therapeutic purposes.
Polyplus-transfection
Acquisition in 2023
Polyplus-transfection SA is a biotechnology company based in Illkirch-Graffenstaden, France, specializing in the development and sale of solutions for nucleic acid delivery across research, bioproduction, and therapeutic applications. Established in 2001 and ISO 9001-certified since 2002, the company offers a diverse range of proprietary reagents for the transfection of genes, oligonucleotides, and siRNA. These products facilitate various applications including enhanced in vivo delivery, molecular biology, diagnostics, gene expression, RNA interference, and protein production. Polyplus-transfection's reagents are increasingly utilized in clinical trials globally, supported by a network of distributors. The company also holds a comprehensive portfolio of patents and licenses, featuring innovative methods for therapeutic siRNA delivery.
Albumedix
Acquisition in 2022
Albumedix is a biotechnology company based in Nottingham, England, specializing in the development of albumin-based technologies that enhance biopharmaceuticals. With over 30 years of experience, the company focuses on creating superior drug formulations and stabilizing vaccines, thereby improving therapies for patients with serious diseases. Albumedix partners with pharmaceutical companies to provide innovative solutions that facilitate the formulation of advanced therapeutics, including drug conjugates and cell therapy formulations. The company's dedication to advancing albumin-enabled therapies has established it as a leader in the field, with its products and technologies utilized in both clinical and marketed drugs worldwide. With a team of over 80 professionals, Albumedix is committed to enhancing patient quality of life through its cutting-edge biopharmaceutical solutions.
Novasep - Chromatography Equipment
Acquisition in 2022
Novasep - Chromatography Equipment comprises resin-based batch and intensified chromatography systems, and focuses on low & high pressure for small and large molecules such as monoclonal antibodies, oligonucleotides, peptides and insulin.
ALS Automated Lab Solutions
Acquisition in 2021
ALS Automated Lab Solutions specializes in providing advanced laboratory services for life science applications. The company offers the ALS CellCelector, an automated system designed for fluorescence imaging, selection, and precise picking of clones or single cells, which is essential for mammalian cell line generation. This innovative platform combines cutting-edge robotic technology with sophisticated image processing software, enabling the scanning of cell culture plates to accurately identify and select target cells or colonies. The ALS CellCelector ensures high image quality and precision in picking, incorporates real-time image-based quality control, and eliminates the risk of cross-contamination through the use of disposable tips. Additionally, it requires no routine maintenance, making it a reliable solution for researchers aiming to streamline their workflows and enhance experimental outcomes.
Xell is a company that specializes in providing efficient solutions for the biotech and pharmaceutical sectors, focusing primarily on cell culture technology. It offers a range of products designed to improve the production of biopharmaceuticals, diagnostic proteins, viral vectors, and vaccines utilizing mammalian cell lines. Xell's product portfolio includes cell culture media, cell culture feeds, dietary supplements, and custom formulations tailored to the specific needs of its clients. With a team of experienced experts, Xell collaborates closely with healthcare organizations to address their cell culture challenges, leveraging advanced analytical tools for the in-depth characterization of biological systems and pharmaceutical proteins. The company aims to deliver optimal solutions that enhance the capabilities of its customers in bioprocessing.
CellGenix
Acquisition in 2021
CellGenix is a manufacturer specializing in raw and ancillary materials for cell and gene therapy as well as regenerative medicine. The company develops, produces, and markets human cytokines, growth factors, and other recombinant cell culture components, offered in both preclinical and GMP quality. Additionally, CellGenix provides proprietary serum-free media specifically designed for the manufacturing of Advanced Therapy Medicinal Products (ATMPs). Their products support academia and industry partners in clinical trials and commercial manufacturing globally. With extensive expertise in cell culture and regulatory processes, CellGenix is well-equipped to meet the stringent requirements faced by customers during product development and regulatory approval.
Biological Industries
Acquisition in 2019
Biological Industries is a manufacturer specializing in life science research products focused on cell culture and molecular biology. The company develops and produces cell culture media specifically designed for stem cell research and potential cell therapy applications. Its expertise encompasses the manufacturing of stem cell culture and differentiation media, human cytogenetics, tissue culture, and custom cell media formulation. Additionally, Biological Industries offers contract manufacturing services, mycoplasma detection and elimination solutions, and products for assessing cell proliferation and viability, including QF-PCR test kits. By providing these specialized products, the company supports academic institutions, biotechnical firms, and pharmaceutical companies in their research and development endeavors in the fields of cell therapy and molecular biology.
Danaher Life Science
Acquisition in 2019
Danaher Life Sciences provide scientists with meaningful research tools and services to gain a better understanding of biological and chemical matters. The combined efforts of Beckman Coulter Life Sciences, SCIEX, Molecular Devices, Pall, and Leica Microsystems work synergistically to provide increasingly sophisticated technologies designed to integrate across systems faster and with more accurate data.
ForteBio
Acquisition in 2019
ForteBio is a life science company that specializes in developing analytical systems for the rapid and real-time quantification and characterization of proteins and their interactions. The company offers a range of instruments known as the Octet family, designed to provide scientists with detailed information about biomolecular interactions in micro-volume sample sizes. These systems facilitate the analysis of proteins, peptides, DNA, RNA, and small molecules in a microplate format. Among its key products are the Octet RED, which enables quantitation and kinetic analysis while supporting small molecule screening, as well as the Octet Q and QK models, which also focus on quantitation and kinetics. Through these advanced tools, ForteBio aims to enhance research capabilities in the field of biomolecular interactions.
MKS Umetrics
Acquisition in 2017
MKS Umetrics is a prominent provider of data analytics software focused on enhancing biopharmaceutical development and manufacturing processes. The company's software solutions include tools for predictive modeling, design of experiments (DOE), and multivariate data analysis (MVDA). These offerings enable clients to optimize their operations and improve decision-making by leveraging advanced analytical methodologies. Through its innovative software, MKS Umetrics aims to add significant value to businesses in the biopharmaceutical sector.
Essen BioScience
Acquisition in 2017
Essen BioScience Inc. is a leading developer and manufacturer of innovative instruments, software, reagents, and consumables aimed at life science researchers worldwide. Established in 1996 and based in Ann Arbor, Michigan, the company specializes in cell-based in vitro assays and instrumentation. Its flagship product, the IncuCyte S3, is a real-time quantitative live-cell imaging and analysis platform that facilitates the visualization and quantification of cell behavior over extended periods by automatically capturing and analyzing images within a standard laboratory incubator. This technology allows researchers to conduct live-cell experiments and obtain quantitative data analysis with ease. Essen BioScience has a strong reputation for pioneering advancements in optical cell-based screening, high-throughput electrophysiology, and kinetic imaging, contributing significantly to the field and generating substantial sales globally. In April 2010, the company rebranded from Essen Instruments Inc. and has since operated as a subsidiary of Sartorius Aktiengesellschaft.
ViroCyt
Acquisition in 2016
ViroCyt is a biotechnology company based in Broomfield, Colorado, founded in 2012. It specializes in the development and commercialization of innovative technologies that enable the rapid quantification of viruses. ViroCyt aims to enhance critical processes in various fields, including vaccine manufacturing, protein expression, and antiviral development. Its tools are utilized by vaccine companies, biotechnology firms, and research institutions, both domestically and internationally, to improve efficiency and outcomes in settings where viruses are a significant factor.
kSep Systems
Acquisition in 2016
kSep Systems, LLC, founded in 2011 and based in Morrisville, North Carolina, specializes in producing automated single-use bioprocessing solutions. The company's primary technology, kSep, is designed to harvest cells as either a product or by-product during manufacturing processes. This technology retains particles such as cells or microcarriers in a concentrated fluidized bed under continuous media or buffer flow. It serves clients in recombinant therapeutics, cell therapy, and vaccine manufacturing, offering applications like harvest clarification and concentrate-wash-harvesting. kSep Systems provides engineering expertise and cGMP manufacturing services to create robust bioprocessing solutions. The company is currently a subsidiary of Sartorius Stedim Biotech S.A., having previously been part of KBI Biopharma Inc.
IntelliCyt
Acquisition in 2016
IntelliCyt Corporation, founded in 2006 and based in Albuquerque, New Mexico, specializes in developing high-throughput cell and bead-based screening solutions for the life sciences sector. The company utilizes proprietary technologies to create its iQue Screener platform, which integrates instruments, software, and reagents for multiplexed analysis of samples in liquid suspension. IntelliCyt's offerings include ForeCyt software for data visualization and analysis, as well as MultiCyt screening kits designed for use with iQue Screeners. These products cater to the needs of pharmaceutical and biotechnology companies, as well as medical centers, by significantly increasing the speed and efficiency of detecting and measuring cells and beads. The company addresses critical demands in drug discovery, antibody discovery, and in vitro toxicology, providing earlier and more relevant results while reducing costs. IntelliCyt operates as a subsidiary of Sartorius AG and is recognized for pioneering high-throughput screening technologies that enhance productivity in modern life sciences research.
Cellca
Acquisition in 2015
Cellca is a specialized technology and service provider that focuses on upstream processes for mammalian protein manufacturing. The company develops cell lines and offers fermentation processes tailored for biopharmaceutical products. Through its proprietary process technologies, Cellca enhances the efficiency, robustness, and scalability of large-scale protein production in mammalian cells, making the manufacturing process faster and more cost-effective. Their expertise in process development positions them as a key player in the biopharmaceutical industry, addressing the increasing demand for biologics.
TAP Biosystems Group
Acquisition in 2013
TAP Biosystems Group is a company that specializes in the design, development, and manufacture of automated cell culture and fermentation systems. Its technology is utilized in pharmaceutical, biotechnology, and academic laboratories, facilitating bioprocess development and Good Manufacturing Practice (GMP) production of biologics and cell therapies. Additionally, TAP Biosystems supports various research programs, including those focused on discovery and stem cell research. The company's innovative solutions play a crucial role in advancing biotechnological applications and enhancing laboratory efficiency.