Notable Labs, Inc. develops and operates a platform that provides lab testing services for brain cancer patients. The company runs drug combination experiments on the tumor and gives a report back to the patient’s doctor. Notable Labs, Inc. was formerly known as StemCycle, Inc. The company was incorporated in 2014 and is based in Foster City, California.
Foresight Mental Health is a technology-enabled company focused on providing comprehensive psychiatry and therapy services. It employs a team of psychiatrists, therapists, and psychiatric nurse practitioners who deliver treatment directly to patients in its clinics. Foresight aims to transform mental healthcare by integrating advanced technology developed by its software and biomedical engineers with clinical practice. The company offers a wide range of mental health treatments and wellness services, utilizing patient profiles that incorporate scientific research, genetic information, and detailed assessments of symptoms and brain chemistry. This holistic approach is designed to enhance patient outcomes, promoting improved mental health and overall well-being.
Octant Bio is focused on advancing health and treating complex diseases through innovative synthetic technology. The company utilizes a combination of synthetic biology, genome engineering, next-generation sequencing, and computational methods to assess the activity of numerous receptor pathways within human cells. This approach allows for the development of multi-targeted small molecule drug leads by leveraging machine learning to engineer compounds that interact with multiple receptors. By generating extensive multi-receptor pathway data, Octant Bio aims to enhance rational drug design and uncover new therapeutic possibilities. Founded in 2017 and based in Los Angeles, California, Octant Bio is dedicated to transforming the landscape of drug discovery and development.
Alto Neuroscience Inc is a clinical-stage biopharmaceutical company with a mission to redefine psychiatry by leveraging individuals' neurobiology to develop personalized and effective treatment options. The company currently consists of different clinical-stage assets such as ALTO-100, ALTO-202, ALTO-101, and ALTO-300 among others initially targeting depressive disorders and schizophrenia populations as identified by independent brain-based biomarkers.
Bionaut Labs is a biotechnology company that specializes in developing an intra-tissue navigation platform using nano and micro-robots for medical applications. Founded in 2016 and headquartered in California, Bionaut Labs focuses on creating a delivery mechanism that allows for anatomically precise navigation within the body. The company's innovative micro-robotic technology is designed to access any anatomical location, enabling medical professionals to perform complex surgical procedures remotely and without external incisions. This advancement is achieved through an advanced remote control and imaging system that accurately guides the robots to their targets, monitors their progress, and triggers the release of therapeutic payloads at the appropriate locations and times.
Eigen Therapeutics is a biotechnology company dedicated to developing innovative therapies that enhance the detection and treatment of cancer. The company specializes in "priming" therapies, which help targeted treatments become more effective by addressing cancer heterogeneity and increasing the vulnerability of cancer cells, while simultaneously improving the resilience of healthy cells. Eigen is creating a high-throughput discovery platform that combines biology and engineering, utilizing proprietary machine learning algorithms to identify new drug classes and therapeutic approaches. This platform incorporates robotic systems, laboratory operations software, and machine learning analysis pipelines, all developed in-house. By focusing on combination therapeutics that improve efficacy and reduce toxicity, Eigen aims to provide physicians with access to novel treatments for patients with unmet medical needs, ultimately striving to enhance patient outcomes and save lives.
Circularis Biotechnologies, Inc. is a biotechnology company established in 2014 and based in California. The company focuses on developing innovative methods to regulate gene expression, aiming to enhance the production yields of biotherapeutics. Circularis offers a range of products, including RACRE Variant Libraries, hCMV Variant Library, and T7 Variant Library, as well as services such as RACRE Enhancement, RACRE Discovery, RACRE Technology Access Program, and Ribozyme Analysis of Cis-Regulatory Elements. By improving the targeting of gene therapy and optimizing gene expression in under-researched organisms, Circularis seeks to advance the fields of gene therapy, biomanufacturing, and synthetic biology, ultimately benefiting medical practitioners and enhancing therapeutic outcomes.
NutriSense, Inc. is a Chicago-based company established in 2019 that focuses on personalizing nutrition through advanced continuous glucose monitoring and machine learning technology. The company offers a monthly subscription service that includes a glucose sensor and a mobile application for tracking meals, activities, and fasting. NutriSense aims to help clients understand their metabolism and manage their health effectively by providing tailored dietary recommendations and access to personal dietitians. Through its innovative approach, NutriSense seeks to empower individuals to create a diet that is uniquely suited to their needs.
BioROSA Technologies Inc. develops a blood test for autism spectrum disorders (ASD). The company offers diagnostic tools to allow clinicians to determine who is at risk for ASD and enables therapeutic developments through blood-based biomarkers and machine learning tools. BioROSA Technologies Inc. was incorporated in 2018 and is based in Belmont, Massachusetts.
Enveda Therapeutics is constructing and decoding the largest integrated dataset of anthropological, biological, and chemical information from medicinal plants to inspire new medicines.
Juno Diagnostics, Inc. is a health technology company based in San Diego, California, focused on democratizing access to genetic information. Established in 2017, Juno specializes in cell-free DNA-based prenatal testing and is also engaged in the development of genetic testing tools for various applications, including epigenetics, inherited diseases, and cancer diagnostics. The company aims to create simple and cost-effective devices that facilitate point-of-need genetic testing, thereby enhancing accessibility to vital health information.
HepaTx Corporation, founded in 2015 and located in Palo Alto, California, focuses on developing regenerative medicine solutions for liver diseases. The company aims to address the critical need for improved therapies for life-threatening liver conditions through its innovative technology, which was developed at Stanford University. HepaTx specializes in producing hepatocytes, the primary functional cells of the liver, for therapeutic use. This approach has the potential to restore lost liver function in patients with end-stage liver disease, offering an alternative to costly and complex organ transplants. By harnessing the principles of regenerative medicine, HepaTx's therapies enable the body to repair damaged liver tissues, providing a cost-effective solution for previously untreatable cases.
Based in the Boston biotech and medtech hub, Elucid Bioimaging is focused on improving the accuracy, experience, & cost-effectiveness of cardiovascular diagnostic imaging by leveraging machine learning. Elucid's main product, vascuCAP, is the first-ever, FDA-cleared, histologically-validated software for evaluating plaque vulnerability from a single CTA to inform risk of event (heart attack or stroke) & treatment selection. Additionally, Elucid works with pharmaceutical companies, providers, and research organizations to provide quantitative image analysis services.
IVIVA Medical, Inc. develops bio-artificial platforms and systems to provide therapies. It develops alternative end-state renal disease therapies that alleviate donor organ demand for patients; disease and pathology modeling; and bioreactor systems. The company was incorporated in 2013 and is based in Beverly, Massachusetts.
IVIVA Medical, Inc. develops bio-artificial platforms and systems to provide therapies. It develops alternative end-state renal disease therapies that alleviate donor organ demand for patients; disease and pathology modeling; and bioreactor systems. The company was incorporated in 2013 and is based in Beverly, Massachusetts.
Developer of virus-resistant live bacterial products designed to modulate the human microbiome. The company targets the viral components of the gut microbiome to treat disease and focus on healthy gut bacteria and their predatory phages to engineer resistant strains, and also develops a new class of live biotherapeutics, enabling medical science professionals to specifically target phages or viruses with a specific affinity for inducing lysis.
Contraline, Inc. is a biotechnology company based in Charlottesville, Virginia, focused on developing innovative male birth control solutions. The company has created Echo-V, an ultrasound-visible polymer solution that is injected into the vas deferens, forming a semi-permeable hydrogel device that blocks sperm while allowing bodily fluids to pass through. This product is part of a non-surgical procedure known as Vasintomy. Contraline's first product, Adam, utilizes a proprietary injectable hydrogel platform and is designed for a minimally invasive outpatient procedure. Adam is non-hormonal, intended to provide effective contraception for several years, and can be easily reversed. Established in 2015, Contraline aims to advance reproductive health through its unique approaches to male contraception.
Repair Biotechnologies, Inc. is a biotechnology company based in Syracuse, New York, established in 2018. The company focuses on developing innovative gene and protein therapies aimed at reversing age-related conditions such as immunosenescence and atherosclerosis. It addresses critical issues like thymic atrophy and the associated decline in immune function, which are prevalent in aging populations. By targeting the root causes of age-related diseases, Repair Biotechnologies aims to enhance the health span of individuals and improve overall well-being. The company employs a cholesterol-degrading platform to tackle localized accumulations of excess cholesterol, promoting safe and effective treatments for related medical conditions.
Octagon Therapeutics, a preclinical-stage biopharmaceutical company developing antibiotics for multi-drug resistant infections, Octagon has demonstrated effectiveness against the most critical pathogens as identified by the WHO. Octagon World Headquarters is based in the Pagliuca Life Lab directly adjacent to Harvard campus. This state-of-the-art facility has allowed Octagon to accelerate the development of our vital medicines with minimal overhead and equipment costs.
Octagon’s management team includes highly skilled scientists, clinicians, and entrepreneurs with decades of research experience and deep expertise in drug development. The scientific team is growing and continues to add top research talent.
Circularis Biotechnologies, Inc. is a biotechnology company established in 2014 and based in California. The company focuses on developing innovative methods to regulate gene expression, aiming to enhance the production yields of biotherapeutics. Circularis offers a range of products, including RACRE Variant Libraries, hCMV Variant Library, and T7 Variant Library, as well as services such as RACRE Enhancement, RACRE Discovery, RACRE Technology Access Program, and Ribozyme Analysis of Cis-Regulatory Elements. By improving the targeting of gene therapy and optimizing gene expression in under-researched organisms, Circularis seeks to advance the fields of gene therapy, biomanufacturing, and synthetic biology, ultimately benefiting medical practitioners and enhancing therapeutic outcomes.
Volumetric, Inc. develops bioprinting platform, which offers 3D bioprinters creating vascularized human tissue. It provides bioprinters and bio inks for applications in the life sciences, drug discovery, and medical devices. The company was incorporated in 2014 and is based in Houston, Texas.
VastBiome is a biotechnology company that mines microbiome drugs to treat cancer and autoimmune disease. The company employs its proprietary methods in genomic sequencing, artificial intelligence, and synthetic biology to discover biomarkers and therapeutics for challenging immunologic disorders. It offers a platform that aims to aggregate public and private data in order to generate a microbiome database and leverages analytical processes to discover connections between distinct and biologically related data in order to increase statistical power and drive discovery. In addition, the platform can be used to identify novel biomarkers to risk-stratify patients and predict clinical outcomes. It was co-founded by Peter McCaffrey, Kovi Bessoff, Ayin Vala, and Kareem Barghouti in Millbrae, California in 2018.
Contraline, Inc. is a biotechnology company based in Charlottesville, Virginia, focused on developing innovative male birth control solutions. The company has created Echo-V, an ultrasound-visible polymer solution that is injected into the vas deferens, forming a semi-permeable hydrogel device that blocks sperm while allowing bodily fluids to pass through. This product is part of a non-surgical procedure known as Vasintomy. Contraline's first product, Adam, utilizes a proprietary injectable hydrogel platform and is designed for a minimally invasive outpatient procedure. Adam is non-hormonal, intended to provide effective contraception for several years, and can be easily reversed. Established in 2015, Contraline aims to advance reproductive health through its unique approaches to male contraception.
Contraline, Inc. is a biotechnology company based in Charlottesville, Virginia, focused on developing innovative male birth control solutions. The company has created Echo-V, an ultrasound-visible polymer solution that is injected into the vas deferens, forming a semi-permeable hydrogel device that blocks sperm while allowing bodily fluids to pass through. This product is part of a non-surgical procedure known as Vasintomy. Contraline's first product, Adam, utilizes a proprietary injectable hydrogel platform and is designed for a minimally invasive outpatient procedure. Adam is non-hormonal, intended to provide effective contraception for several years, and can be easily reversed. Established in 2015, Contraline aims to advance reproductive health through its unique approaches to male contraception.
RockStep Solutions, Inc. is a software development company based in Portland, Maine, focused on modernizing information management in laboratory settings. Founded in 2014, the company offers its flagship product, Climb, a cloud-based application that enhances collaboration among animal caretakers, laboratory technicians, and researchers. Climb addresses operational inefficiencies and data management challenges in drug discovery by providing features such as job and sample tracking, customizable workflows, scheduling, and inventory management. The platform is designed to be accessible on mobile devices, thereby facilitating seamless communication and improving productivity within tier-1 pharmaceutical companies, biotechnology firms, contract research organizations, and academic institutions.
Excision BioTherapeutics Inc. is a life science company based in Philadelphia, Pennsylvania, that specializes in the development of gene editing therapeutics targeting life-threatening diseases caused by neurotropic viruses. Founded in 2015, the company employs CRISPR-based technology to create innovative treatments that aim to eradicate or disrupt viral genes in human patients. Excision is committed to advancing these therapeutics into safe and effective medicines, addressing significant medical needs and improving the quality of life for individuals affected by viral infections.
Foresight Mental Health is a technology-enabled company focused on providing comprehensive psychiatry and therapy services. It employs a team of psychiatrists, therapists, and psychiatric nurse practitioners who deliver treatment directly to patients in its clinics. Foresight aims to transform mental healthcare by integrating advanced technology developed by its software and biomedical engineers with clinical practice. The company offers a wide range of mental health treatments and wellness services, utilizing patient profiles that incorporate scientific research, genetic information, and detailed assessments of symptoms and brain chemistry. This holistic approach is designed to enhance patient outcomes, promoting improved mental health and overall well-being.
Thryve, Inc. specializes in microbiome testing and personalized probiotics aimed at enhancing immunity and gastrointestinal health. Founded in 2016 and based in Sunnyvale, California, the company offers a subscription-based testing kit that analyzes gut bacteria to provide tailored dietary and lifestyle recommendations. Users receive comprehensive reports detailing the types of microbes present in their bodies, along with insights on their microbiome diversity and overall gut wellness. Thryve's platform not only supports individual users in understanding their microbiomes but also facilitates collaboration among citizen scientists, researchers, and pharmaceutical companies to deepen knowledge of microbiome health. The company's services cater to customers in the United States, focusing on actionable insights that help in the prevention of chronic diseases such as obesity, cystic fibrosis, and Alzheimer's.
Suggestic, Inc. is a technology company based in San Francisco that specializes in personalized lifestyle and nutrition coaching through its innovative application. Founded in 2014, Suggestic empowers health-related organizations, including clinicians and nutritionists, to create tailored nutrition programs efficiently and cost-effectively using white label solutions or direct API integration. The platform utilizes proprietary artificial intelligence to encode dietary programs into rulesets, enabling the collection of user data through assessments, lab tests, and devices. By analyzing this data, Suggestic offers users personalized meal plans, smart shopping lists, recipe suggestions, and restaurant recommendations tailored to their dietary goals and preferences. The company's focus on precision eating aims to help individuals lose weight, enhance vitality, and manage chronic diseases.
Thryve, Inc. specializes in microbiome testing and personalized probiotics aimed at enhancing immunity and gastrointestinal health. Founded in 2016 and based in Sunnyvale, California, the company offers a subscription-based testing kit that analyzes gut bacteria to provide tailored dietary and lifestyle recommendations. Users receive comprehensive reports detailing the types of microbes present in their bodies, along with insights on their microbiome diversity and overall gut wellness. Thryve's platform not only supports individual users in understanding their microbiomes but also facilitates collaboration among citizen scientists, researchers, and pharmaceutical companies to deepen knowledge of microbiome health. The company's services cater to customers in the United States, focusing on actionable insights that help in the prevention of chronic diseases such as obesity, cystic fibrosis, and Alzheimer's.
Intelligent Implants specializes in developing wireless implantable electronics designed to stimulate, steer, and monitor bone growth. The company provides electrotherapeutic devices that address various diseases and support the recovery of bone and other tissues. By integrating data, engineering, and medicine, Intelligent Implants creates innovative, active, and connected medical devices aimed at improving patient treatment and assisting healthcare professionals in their decision-making processes. Founded in 2014 in Cork, the company was established by Erik Zellmer, Rory Murphy, Martin Larsson, and John Zellmer.
Leucadia Therapeutics Inc is a privately-held, pre-clinical stage company based in Riverside, California, focused on the prevention and treatment of Alzheimer's disease. The company is developing an implantable device called Arethusta, which aims to restore cerebrospinal fluid flow and enhance the clearance of toxic metabolites from the brain's early affected regions. This innovative approach seeks to prevent the onset of Alzheimer's disease, particularly in individuals with mild cognitive impairment. Additionally, Leucadia is working on a diagnostic algorithm that leverages big data to assess Alzheimer's disease risk. The company's efforts are geared towards providing effective therapeutic solutions and improving the quality of care for patients at risk of neurodegeneration.
OccamzRazor is a San Francisco-based AI-neuroscience startup dedicated to developing disease-modifying treatments for Parkinson's Disease and other complex ailments. The company employs a computational approach that leverages both structured and unstructured biomedical data, including published literature and clinical trial results. By constructing a comprehensive knowledge graph that encapsulates all known information about Parkinson's Disease, OccamzRazor facilitates enhanced therapeutic insights and informed decision-making in biomedical research. This platform aims to identify new therapeutic targets and support strategic drug development, addressing the multifactorial nature of complex diseases like Parkinson's.
EnClear Therapies, Inc. is a life sciences company based in Newburyport, Massachusetts, focused on developing device-based therapies for neurodegenerative diseases. The company specializes in the delivery and monitoring of cerebrospinal fluid (CSF) and has created a proprietary therapeutic platform aimed at removing toxic proteins from the CSF. EnClear's products are primarily designed to improve the lives of patients suffering from conditions such as Amyotrophic Lateral Sclerosis (ALS) and Progressive Supranuclear Palsy (PSP). By providing innovative solutions in the treatment of these neurological diseases, EnClear Therapies aims to help halt disease progression and extend patient lifespans.
Blue Mesa Health Inc., digital therapeutics company, develops and operates a platform to deliver diabetes prevention program. The company offers Transform, which is a digital health platform that helps in reversing prediabetes through health coaching and support. It product caters to healthcare sector. The company was founded in 2015 and is based in New York, New York. As of January 9, 2020, Blue Mesa Health Inc. operates as a subsidiary of Virgin Pulse, Inc.
Blue Mesa Health Inc., digital therapeutics company, develops and operates a platform to deliver diabetes prevention program. The company offers Transform, which is a digital health platform that helps in reversing prediabetes through health coaching and support. It product caters to healthcare sector. The company was founded in 2015 and is based in New York, New York. As of January 9, 2020, Blue Mesa Health Inc. operates as a subsidiary of Virgin Pulse, Inc.
Ligandal Inc. is a biotechnology company based in Oakland, California, that specializes in developing therapeutic nanotechnologies. Founded in 2013 and previously known as Ligandal Technology LLC, the company focuses on creating personalized gene therapies aimed at curing various diseases. Ligandal employs a ligand discovery engine to design materials that can accurately deliver a range of genetic materials and gene-specific payloads, including CRISPR and mRNA, to specific cell types with high precision. The company is initially targeting applications in gene editing within the fields of hematology and immuno-oncology, emphasizing its commitment to advancing the discovery and delivery of innovative gene therapies.
Notable Labs, Inc. develops and operates a platform that provides lab testing services for brain cancer patients. The company runs drug combination experiments on the tumor and gives a report back to the patient’s doctor. Notable Labs, Inc. was formerly known as StemCycle, Inc. The company was incorporated in 2014 and is based in Foster City, California.
CrowdMed, Inc. is a healthcare technology company based in San Francisco, California, established in 2012. It utilizes a prediction market platform to address complex medical issues by tapping into the collective intelligence of a network of medical detectives, which includes licensed physicians, medical students, and other healthcare professionals. This innovative approach allows CrowdMed to provide patients with potential diagnoses and solutions for undiagnosed or chronic symptoms that have eluded traditional medical practices. By combining the insights of numerous contributors, CrowdMed aims to deliver accurate and timely medical suggestions, thereby streamlining the healthcare process. The company seeks to become a trusted resource for millions of patients facing challenging medical conditions.
At Echo, we believe health is about people not pills. That’s why we’ve created a new kind of pharmacy. One that comes to you, not the other way around. We start with being brilliant at fulfilling prescriptions, because getting people taking the right medicine is the first step in staying well. But there’s more we can do. It’s not just patients we support, its partners. Together with other like-minded pharmacies, GPs and prescribing services we deliver even more positive experiences. Ultimately, we want to help patients understand and do more for themselves, so together they can make the right decisions with their GPs. And when it comes time to improve our health, we all know more Technology should make the future of health care more human. So ours comes packed with care.
Echo is a provider of am automated microscope intended for biological research and pathologies. The company's product provides features like inverted images, cell counting, phase contrast, brightfield and fluorescence, enabling customers to have accurate images at a lower cost.
Notable Labs, Inc. develops and operates a platform that provides lab testing services for brain cancer patients. The company runs drug combination experiments on the tumor and gives a report back to the patient’s doctor. Notable Labs, Inc. was formerly known as StemCycle, Inc. The company was incorporated in 2014 and is based in Foster City, California.