Arvinas
Arvinas, Inc. is a clinical-stage biopharmaceutical company based in New Haven, Connecticut, focused on developing therapies that target and degrade disease-causing proteins. The company employs its proprietary Proteolysis-Targeting Chimera (PROTAC) technology, which harnesses the body's own cellular mechanisms to eliminate harmful proteins. Arvinas' lead product candidates include ARV-110, currently in phase I clinical trials for treating metastatic castration-resistant prostate cancer by targeting the androgen receptor, and ARV-471, aimed at treating metastatic ER-positive/HER2-negative breast cancer through estrogen receptor degradation. Additionally, the company is exploring other PROTACs and therapeutic options for neurodegenerative diseases. Founded in 2015, Arvinas has established collaborations with major pharmaceutical companies such as Pfizer, Genentech, and Bayer to advance its innovative drug development efforts.
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