Eli Lilly and Company

Insilico Medicine, Inc. is a biotechnology company that leverages artificial intelligence (AI) to transform drug discovery, biomarker development, and aging research. Founded in 2014 and based in Baltimore, Maryland, the company has established itself as a pioneer in applying advanced AI techniques, such as generative adversarial networks and reinforcement learning, to create novel molecular structures for various diseases, including cancer and age-related conditions. Insilico Medicine operates an integrated platform that covers all stages of drug discovery, from initial research to clinical trial analysis. Its projects include Pharma.AI, which offers machine learning services to various sectors, and Young.AI, a platform focused on aging predictors. The company also pursues internal drug discovery initiatives targeting diseases like Alzheimer's and Parkinson's, and has partnered with Life Extension to produce nutraceutical products utilizing deep learning and bioinformatics. Additionally, Insilico Medicine provides consumer applications aimed at enhancing health and longevity.

Sunbird Bio is a diagnostics platform developer focused on advancing molecular diagnostics to deliver faster and more accurate results. Founded by Huilin Shao, the company specializes in detecting a wide array of diseases, including infectious diseases, neurodegenerative disorders, and cancer. By enabling early diagnosis, Sunbird Bio aims to enhance healthcare outcomes and support physicians in making informed decisions. The platform is designed to improve clarity and accessibility in diagnostic testing, thereby contributing to better patient care.

Amprion is a biotechnology company specializing in the development of diagnostic tests for brain diseases. Founded in 2007, it is headquartered in San Francisco, California. The company focuses on detecting pathological α-synuclein in cerebrospinal fluid to aid clinicians in diagnosing neurodegenerative conditions like Parkinson's and Lewy body dementia.

Ionetix Corporation specializes in the development, manufacturing, and distribution of superconducting cyclotrons designed for point-of-care production of positron emission tomography (PET) radioisotopes. Established in 2010, the company is headquartered in San Francisco, California, with an additional location in Lansing, Michigan. Ionetix offers the ION-12SC system, which produces N-13 ammonia for PET myocardial perfusion imaging. Its compact cyclotron technology provides advantages such as smaller size, lighter weight, lower power requirement, and a reduced price point compared to conventional designs. The company installs, operates, and manages cyclotrons near imaging suites to provide necessary doses of Ammonia N-13.

RetiSpec is developing a non-invasive eye scanner for the early detection of Alzheimer’s Disease pathology years before symptoms occur. This enables clinicians to intervene with emerging therapeutics at an earlier stage when there's a chance of impacting the disease.

Alumis is a clinical-stage biopharmaceutical company specializing in precision medicines for autoimmune disorders. It leverages its proprietary precision data analytics platform and expertise in immunology to develop targeted therapies that significantly improve patients' lives.

Beijing Targeting One Technology Co., Ltd. specializes in the development and production of biomedical instruments and consumables, focusing on in vitro diagnostic reagents for precision medicine, health management, and life science research. Established in 2015 and based in Beijing, the company offers a range of products including sample preparation apparatus, biochip readers, digital PCR supplies, and genetic testing kits. Its digital PCR solutions play a crucial role in medical diagnostics, with applications in transplant rejection monitoring, targeted sequencing, tumor liquid biopsy, and non-invasive prenatal screening. Targeting One aims to enhance gene testing and precision medicine through its innovative technologies and comprehensive offerings.

Alto Neuroscience is a clinical-stage biopharmaceutical company focused on redefining psychiatry through the integration of patient neurobiology into the drug development process. Utilizing an AI-enabled biomarker platform, the company combines diverse information about patients' brain activity and behavior to create personalized and effective treatment options. Alto Neuroscience is developing several clinical assets, including ALTO-100, ALTO-202, ALTO-101, and ALTO-300, primarily targeting depressive disorders and schizophrenia, identified through independent brain-based biomarkers. By moving away from traditional trial-and-error methods, the company aims to align its innovative therapies with the specific needs of patients, ultimately improving the management of mental health conditions.

AltPep Corp is a biomedical startup that specializes in diagnosing and treating amyloid diseases, which are known for their complexity and difficulty in management. The company has developed a proprietary peptide-based platform designed to diagnose and neutralize toxic precursors associated with these diseases. This innovative approach includes diagnostic, therapeutic, and anti-biofilm applications, particularly aimed at the early detection of toxic oligomers in Alzheimer's disease through a soluble oligomer binding assay. By focusing on early detection and effective treatment strategies, AltPep aims to enhance healthcare outcomes related to amyloid diseases, ultimately improving human health.

Volastra Therapeutics, Inc. is a biotechnology company focused on developing innovative therapies for metastatic cancers. Established in 2019 and headquartered in New York, the company leverages unique insights into chromosomal instability to create targeted treatment strategies. Volastra utilizes a library of organoids derived from metastatic cancer samples to better understand tumor spread and identify effective therapeutic approaches. Additionally, the company combines artificial intelligence, bioinformatics, and proprietary imaging techniques, which enhance the ability of healthcare professionals to determine which cancers are more likely to metastasize. This approach aims to facilitate quicker target identification, optimize patient selection for therapies, and ultimately improve patient outcomes.

Iterative Scopes, Inc. is a Boston-based company established in 2017 that specializes in developing machine learning-powered diagnostic tools aimed at assisting gastroenterologists in the prevention of colon cancer. The company focuses on providing innovative solutions for physicians and life sciences professionals within the colorectal cancer and inflammatory bowel disease sectors. By leveraging advanced technology, Iterative Scopes aims to enhance diagnostic accuracy and improve patient outcomes in these critical areas of healthcare.

Virtue Diagnostics (Suzhou) Co., Ltd. is an in vitro diagnostic (IVD) company based in Suzhou, China, with a research and development office in Singapore. Founded in 2019, the company specializes in developing advanced diagnostic platforms for the detection of infectious diseases, cancer, and chronic diseases. Its technology offerings include clinical mass spectrometry, multiplex immunohistochemistry for pathology-based cancer detection, and a molecular and immunoassay platform. Virtue Diagnostics aims to enhance diagnostic capabilities and improve patient outcomes through its innovative solutions.

Singleron Biotechnologies Ltd. is a molecular diagnostic company specializing in single cell sequencing solutions. Founded in 2018 and based in Nanjing, China, with additional offices and laboratories in Suzhou, the United States, and Germany, the firm develops a range of innovative products, including the Singleron Matrix automated instrument for high-density microwell processing and GEXSCOPE single cell RNA sequencing kits. The company also offers a microfluidic chip for cell partitioning, magnetic beads for cell barcoding, and tools for data analysis such as CeleScope and SynEcoSys, which facilitate the interpretation of single cell sequencing data. Singleron provides services in single cell RNA sequencing, single nucleus RNA sequencing, and bioinformatics analysis, aiming to advance clinical diagnosis, drug development, and health management. The company collaborates with research institutes, hospitals, and pharmaceutical firms primarily in China and the United States, leveraging its exclusive IP license from Yale University to enhance its innovative capabilities in single cell analysis.

Hopstem Biotechnology LLC is a Houston-based company that focuses on the development of neural stem cell technology and stem cell therapies specifically for neurological disorders. Established in 2019, the company specializes in the neural differentiation, cell banking, and cell engineering of human induced pluripotent stem cells (iPSCs) and human embryonic stem cells (ESCs). By leveraging its advanced technologies, Hopstem aims to enhance biomedical research and improve diagnostic and therapeutic options for various neurological conditions. Through its innovative approaches, the company seeks to provide effective treatment solutions for patients suffering from these disorders.

Scivita Medical is a high-tech enterprise specializing in optical diagnosis and treatment, as well as the development of multidimensional imaging technologies and high-performance materials. The company focuses on precision manufacturing for minimally invasive medical procedures and is recognized for its advancements in endoscopy technology. Scivita Medical offers a range of products that include flexible and rigid endoscopes, featuring innovations such as ultra-high-definition visualization, 3D imaging, and specialized light visualization techniques, including fluorescence. Its portfolio encompasses various medical devices, including 4K medical endoscope camera systems, integrated endoscope systems, and single-use electronic instruments like hysteroscopes, bladder pyeloscopes, and bronchoscopes. These products are designed to provide healthcare professionals with efficient tools for diagnosis and treatment, enhancing the capabilities of modern endoscopic procedures.

Iterative Scopes, Inc. is a Boston-based company established in 2017 that specializes in developing machine learning-powered diagnostic tools aimed at assisting gastroenterologists in the prevention of colon cancer. The company focuses on providing innovative solutions for physicians and life sciences professionals within the colorectal cancer and inflammatory bowel disease sectors. By leveraging advanced technology, Iterative Scopes aims to enhance diagnostic accuracy and improve patient outcomes in these critical areas of healthcare.

Insilico Medicine, Inc. is a biotechnology company that leverages artificial intelligence (AI) to transform drug discovery, biomarker development, and aging research. Founded in 2014 and based in Baltimore, Maryland, the company has established itself as a pioneer in applying advanced AI techniques, such as generative adversarial networks and reinforcement learning, to create novel molecular structures for various diseases, including cancer and age-related conditions. Insilico Medicine operates an integrated platform that covers all stages of drug discovery, from initial research to clinical trial analysis. Its projects include Pharma.AI, which offers machine learning services to various sectors, and Young.AI, a platform focused on aging predictors. The company also pursues internal drug discovery initiatives targeting diseases like Alzheimer's and Parkinson's, and has partnered with Life Extension to produce nutraceutical products utilizing deep learning and bioinformatics. Additionally, Insilico Medicine provides consumer applications aimed at enhancing health and longevity.

Duality Biologics is a biopharmaceutical company focused on oncology and autoimmune diseases, developing novel modality drugs that include antibody-drug conjugates and bispecific antibodies. It operates a sizable internal pipeline of ADCs and bispecific candidates, with multiple programs in clinical development and several preclinical assets. The company has built a next-generation ADC platform with broad global intellectual property rights and aims to translate novel modalities into approved therapies. Its pipeline comprises numerous in-house ADC candidates, including seven clinical-stage ADCs and two next-generation bispecific ADCs, with additional preclinical programs, and some assets have received regulatory designations such as Fast Track.

Scivita Medical is a high-tech enterprise specializing in optical diagnosis and treatment, as well as the development of multidimensional imaging technologies and high-performance materials. The company focuses on precision manufacturing for minimally invasive medical procedures and is recognized for its advancements in endoscopy technology. Scivita Medical offers a range of products that include flexible and rigid endoscopes, featuring innovations such as ultra-high-definition visualization, 3D imaging, and specialized light visualization techniques, including fluorescence. Its portfolio encompasses various medical devices, including 4K medical endoscope camera systems, integrated endoscope systems, and single-use electronic instruments like hysteroscopes, bladder pyeloscopes, and bronchoscopes. These products are designed to provide healthcare professionals with efficient tools for diagnosis and treatment, enhancing the capabilities of modern endoscopic procedures.

Jaguar Gene Therapy is developing gene therapy treatments for severe genetic diseases. Its clinical-stage pipeline focuses on neurodevelopmental disorders, Type 1 galactosemia, and Type 1 diabetes.

Founded in 2008, Nucleix Ltd. specializes in developing non-invasive molecular diagnostic tests for early cancer detection. Its proprietary tests, Bladder EpiCheck and Lung EpiCheck, identify subtle methylation changes in urine and blood samples respectively.

Beijing Targeting One Technology Co., Ltd. specializes in the development and production of biomedical instruments and consumables, focusing on in vitro diagnostic reagents for precision medicine, health management, and life science research. Established in 2015 and based in Beijing, the company offers a range of products including sample preparation apparatus, biochip readers, digital PCR supplies, and genetic testing kits. Its digital PCR solutions play a crucial role in medical diagnostics, with applications in transplant rejection monitoring, targeted sequencing, tumor liquid biopsy, and non-invasive prenatal screening. Targeting One aims to enhance gene testing and precision medicine through its innovative technologies and comprehensive offerings.

MicroTech Medical, founded in January 2011 in Hangzhou Future Technical City, is a company focused on the research, development, and manufacturing of innovative and affordable medical devices for diabetes care. The firm specializes in creating both treatment and monitoring devices aimed at improving diabetes management, primarily serving the Chinese market while also reaching international customers. With significant backing from Eli Lilly and Company, MicroTech Medical is dedicated to enhancing the quality of life for individuals living with diabetes through advanced technology solutions.

Virtue Diagnostics (Suzhou) Co., Ltd. is an in vitro diagnostic (IVD) company based in Suzhou, China, with a research and development office in Singapore. Founded in 2019, the company specializes in developing advanced diagnostic platforms for the detection of infectious diseases, cancer, and chronic diseases. Its technology offerings include clinical mass spectrometry, multiplex immunohistochemistry for pathology-based cancer detection, and a molecular and immunoassay platform. Virtue Diagnostics aims to enhance diagnostic capabilities and improve patient outcomes through its innovative solutions.

Singleron Biotechnologies Ltd. is a molecular diagnostic company specializing in single cell sequencing solutions. Founded in 2018 and based in Nanjing, China, with additional offices and laboratories in Suzhou, the United States, and Germany, the firm develops a range of innovative products, including the Singleron Matrix automated instrument for high-density microwell processing and GEXSCOPE single cell RNA sequencing kits. The company also offers a microfluidic chip for cell partitioning, magnetic beads for cell barcoding, and tools for data analysis such as CeleScope and SynEcoSys, which facilitate the interpretation of single cell sequencing data. Singleron provides services in single cell RNA sequencing, single nucleus RNA sequencing, and bioinformatics analysis, aiming to advance clinical diagnosis, drug development, and health management. The company collaborates with research institutes, hospitals, and pharmaceutical firms primarily in China and the United States, leveraging its exclusive IP license from Yale University to enhance its innovative capabilities in single cell analysis.

BGI is a biotechnology company specializing in genomics. It provides genome sequencing and genetic testing services to research institutions and healthcare professionals worldwide. The company's offerings include bioinformatics, multi-omics solutions, and related tools, catering to a diverse range of clients such as pharmaceutical companies and academic institutions. BGI's work has contributed significantly to genetic and genomic research, with notable collaborations including Eli Lilly and Company, Merck, Pfizer Inc., and the Bill & Melinda Gates Foundation.

Geneseeq Technology Inc., founded in 2008 and based in Toronto, Canada, is a clinical testing and diagnostic center specializing in next-generation sequencing (NGS) technologies for precision medicine in cancer treatment. The company's platform translates patients' genomic information into decision-making tools for physicians and cancer patients. Geneseeq's laboratories have achieved numerous qualifications, including passing assessments from the China’s National Center of Clinical Laboratories, College of American Pathologists, and European Molecular Genetics Quality Network.

Insilico Medicine, Inc. is a biotechnology company that leverages artificial intelligence (AI) to transform drug discovery, biomarker development, and aging research. Founded in 2014 and based in Baltimore, Maryland, the company has established itself as a pioneer in applying advanced AI techniques, such as generative adversarial networks and reinforcement learning, to create novel molecular structures for various diseases, including cancer and age-related conditions. Insilico Medicine operates an integrated platform that covers all stages of drug discovery, from initial research to clinical trial analysis. Its projects include Pharma.AI, which offers machine learning services to various sectors, and Young.AI, a platform focused on aging predictors. The company also pursues internal drug discovery initiatives targeting diseases like Alzheimer's and Parkinson's, and has partnered with Life Extension to produce nutraceutical products utilizing deep learning and bioinformatics. Additionally, Insilico Medicine provides consumer applications aimed at enhancing health and longevity.

Burning Rock Biotech is a cancer diagnostics company that leverages next-generation sequencing and bioinformatics to guide personalized cancer treatment. It develops and provides a portfolio of tissue- and blood-based, NGS-driven therapy selection tests, including OncoScreen Plus, LungPlasma, ColonCore and HRDCore, and evaluates biomarkers such as microsatellite instability, tumor mutation burden, and NTRK fusions across multiple cancer types, including lung, gastrointestinal, prostate, breast, hematologic, thyroid, colorectal, ovarian, pancreatic, and bladder cancers. The company supports clinical and research use through one-stop services spanning genetic testing and companion diagnostic development, operating through central laboratory and in-hospital models. It collaborates with major pharmaceutical companies on clinical trials and research to advance targeted therapies and diagnostics. Founded in 2014, it is headquartered in Guangzhou, with a Guangzhou laboratory and an R&D center in Shanghai, reflecting its focus on expanding access to precision oncology in China.

NuVera Medical, Inc. is a privately held company based in Campbell, California, founded in 2016. It specializes in developing an advanced imaging platform that utilizes 4D ultrasound technology for cardiovascular procedures. The platform is designed for real-time intracardiac echocardiography, enabling healthcare specialists to visualize heart chambers during transcatheter cardiac interventions. By simplifying complex cardiovascular procedures, NuVera Medical aims to support cardiologists in making informed decisions throughout their interventions.

Singlera Genomics Inc. is a biotechnology company that specializes in genetic testing and molecular diagnostic technologies. Founded in 2014 and headquartered in La Jolla, California, with additional operations in Shanghai, China, Singlera develops a methylation detection platform designed for early cancer diagnosis and prevention. The company offers a range of services, including tumor diagnosis, personalized treatment, non-invasive prenatal diagnosis, and pre-implantation genetic screening. Additionally, Singlera is focused on advancing precision medicine, aiming to provide patients with early, accurate, and informative diagnostic solutions to improve healthcare outcomes.

Entrega Bio is a Boston-based company that specializes in developing a proprietary hydrogel technology aimed at improving the oral delivery of injectable substances, including biologics, vaccines, and other medications that typically face absorption challenges. This innovative platform allows for the creation of customizable oral dosage forms that enhance the stability and absorption of large and unstable drug molecules by effectively controlling the gastrointestinal fluid microenvironment. By collaborating with both pharmaceutical and non-pharmaceutical partners, Entrega Bio aims to advance therapeutic and diagnostic applications across various fields, including disease management and mobile health.

NuVera Medical, Inc. is a privately held company based in Campbell, California, founded in 2016. It specializes in developing an advanced imaging platform that utilizes 4D ultrasound technology for cardiovascular procedures. The platform is designed for real-time intracardiac echocardiography, enabling healthcare specialists to visualize heart chambers during transcatheter cardiac interventions. By simplifying complex cardiovascular procedures, NuVera Medical aims to support cardiologists in making informed decisions throughout their interventions.

ReadCoor, Inc. is a technology company based in Cambridge, Massachusetts, specializing in the development and commercialization of a panomic spatial sequencing platform. The company offers the RC2 Platform, which utilizes proprietary Fluorescent in situ Sequencing (FISSEQ) technology to enable researchers, clinicians, and pharmaceutical and diagnostics companies to perform multi-omic analyses. This platform allows for the simultaneous detection and sequencing of numerous RNA, DNA, proteins, and therapeutics while visualizing sub-cellular nanoscale 3D resolution across tissue sections. By integrating high throughput sequencing with morphometric analysis and three-dimensional spatial imaging, ReadCoor provides valuable insights into human biology, facilitating the development of new therapeutics for various conditions, including cancer, infectious diseases, and neurological disorders. Founded in 2016, ReadCoor operates as a subsidiary of 10x Genomics, Inc. as of October 2020.

MicroTech Medical, founded in January 2011 in Hangzhou Future Technical City, is a company focused on the research, development, and manufacturing of innovative and affordable medical devices for diabetes care. The firm specializes in creating both treatment and monitoring devices aimed at improving diabetes management, primarily serving the Chinese market while also reaching international customers. With significant backing from Eli Lilly and Company, MicroTech Medical is dedicated to enhancing the quality of life for individuals living with diabetes through advanced technology solutions.

Singlera Genomics Inc. is a biotechnology company that specializes in genetic testing and molecular diagnostic technologies. Founded in 2014 and headquartered in La Jolla, California, with additional operations in Shanghai, China, Singlera develops a methylation detection platform designed for early cancer diagnosis and prevention. The company offers a range of services, including tumor diagnosis, personalized treatment, non-invasive prenatal diagnosis, and pre-implantation genetic screening. Additionally, Singlera is focused on advancing precision medicine, aiming to provide patients with early, accurate, and informative diagnostic solutions to improve healthcare outcomes.

ACEA Biosciences, Inc., established in 2002 and headquartered in San Diego, California, specializes in developing and commercializing microelectronic sensor systems for cell-based assays, drug discovery, and diagnostics. The company's flagship product, the x-CELLigence System, offers real-time, label-free cell analysis, serving diverse applications such as cell proliferation, cytotoxicity testing, and receptor function monitoring. ACEA's products cater to science research and drug discovery markets, with over 800 customers worldwide and numerous peer-reviewed publications. The company operates a state-of-the-art manufacturing facility in Hangzhou, China, and serves its global customer base as a subsidiary of Agilent Technologies, Inc.

MicroTech Medical, founded in January 2011 in Hangzhou Future Technical City, is a company focused on the research, development, and manufacturing of innovative and affordable medical devices for diabetes care. The firm specializes in creating both treatment and monitoring devices aimed at improving diabetes management, primarily serving the Chinese market while also reaching international customers. With significant backing from Eli Lilly and Company, MicroTech Medical is dedicated to enhancing the quality of life for individuals living with diabetes through advanced technology solutions.

Lodo Therapeutics Corporation is a drug discovery and development company dedicated to creating novel therapeutics derived from natural sources. It focuses on addressing significant health challenges, particularly resistant infectious diseases and cancers, by collaborating with global pharmaceutical companies and leading non-governmental organizations. Founded to realize the scientific vision of Dr. Sean Brady from Rockefeller University, Lodo Therapeutics utilizes a genome-based, culture-independent platform to discover and characterize small molecules sourced from environmental microbial DNA. This innovative approach leverages advancements in DNA sequencing and bioinformatics to explore the untapped potential of microbial evolution, aiming to identify therapeutically valuable pharmaceutical products. Headquartered in New York City at the Alexandria Center for Life Science, Lodo Therapeutics is committed to harnessing the power of nature in the fight against undruggable targets and high unmet medical needs.

ACEA Biosciences, Inc., established in 2002 and headquartered in San Diego, California, specializes in developing and commercializing microelectronic sensor systems for cell-based assays, drug discovery, and diagnostics. The company's flagship product, the x-CELLigence System, offers real-time, label-free cell analysis, serving diverse applications such as cell proliferation, cytotoxicity testing, and receptor function monitoring. ACEA's products cater to science research and drug discovery markets, with over 800 customers worldwide and numerous peer-reviewed publications. The company operates a state-of-the-art manufacturing facility in Hangzhou, China, and serves its global customer base as a subsidiary of Agilent Technologies, Inc.

Caldan Therapeutics is a spinout from the University of Glasgow and the University of Southern Denmark focused on developing therapeutics that modulate free fatty acid receptors to address metabolic diseases, including Type 2 Diabetes, with potential applications in non-alcoholic steatohepatitis and inflammatory conditions. Building on a long-term collaboration between leading researchers, the company seeks to target multiple aspects of diabetes pathology, such as insulin secretion, insulin sensitivity, and islet cell protection, while aiming to reduce inflammatory activity in muscle, liver, and adipose tissue. The approach centers on delivering glucose-lowering effects by modulating receptor pathways implicated in diabetes and related inflammatory diseases.

Avid Radiopharmaceuticals is a Philadelphia-based company focused on the development of molecular imaging agents designed to enhance the medical management of chronic diseases. Its mission centers on creating innovative imaging compounds that facilitate the early identification of pathological changes, thereby supporting earlier diagnosis and improved management of various conditions. Avid's notable product, Amyvid, is an imaging tool utilized in positron emission tomography to detect beta-amyloid plaques in the brain, which plays a crucial role in the assessment of Alzheimer's disease. Through its advancements in molecular imaging, Avid aims to contribute to the development of new therapies and improve clinical outcomes for patients suffering from significant chronic illnesses.

Avid Radiopharmaceuticals is a Philadelphia-based company focused on the development of molecular imaging agents designed to enhance the medical management of chronic diseases. Its mission centers on creating innovative imaging compounds that facilitate the early identification of pathological changes, thereby supporting earlier diagnosis and improved management of various conditions. Avid's notable product, Amyvid, is an imaging tool utilized in positron emission tomography to detect beta-amyloid plaques in the brain, which plays a crucial role in the assessment of Alzheimer's disease. Through its advancements in molecular imaging, Avid aims to contribute to the development of new therapies and improve clinical outcomes for patients suffering from significant chronic illnesses.

Avid Radiopharmaceuticals is a Philadelphia-based company focused on the development of molecular imaging agents designed to enhance the medical management of chronic diseases. Its mission centers on creating innovative imaging compounds that facilitate the early identification of pathological changes, thereby supporting earlier diagnosis and improved management of various conditions. Avid's notable product, Amyvid, is an imaging tool utilized in positron emission tomography to detect beta-amyloid plaques in the brain, which plays a crucial role in the assessment of Alzheimer's disease. Through its advancements in molecular imaging, Avid aims to contribute to the development of new therapies and improve clinical outcomes for patients suffering from significant chronic illnesses.

Hypnion is a neuroscience drug discovery and development company based in Worcester, Massachusetts, founded in 2000. The company specializes in creating innovative therapeutics for central nervous system disorders, particularly focusing on sleep and wake-alertness disorders, as well as circadian rhythm abnormalities. Hypnion utilizes its proprietary drug discovery platform, SCORE-2004, which measures the effects of drugs on sleep and wake parameters. This unique system enables the company to advance its research and development efforts effectively. In recognition of its innovative approach and contributions to the field, Hypnion was acquired by Eli Lilly and Company.

Standard BioTools develops, manufactures, and sells technologies that accelerate biomedical research and medicines development. The company provides standardized, next-generation tools built around proprietary mass cytometry and microfluidics platforms to generate reliable insights into health and disease. Its proteomics and genomics capabilities support a range of applications in translational and clinical research, including oncology, immunology, and immunotherapy. The products are used by academic, government, pharmaceutical, biotechnology, plant and animal research, and clinical laboratories worldwide. By delivering repeatable measurement platforms, Standard BioTools helps researchers translate discoveries into improved patient outcomes.

Avid Radiopharmaceuticals is a Philadelphia-based company focused on the development of molecular imaging agents designed to enhance the medical management of chronic diseases. Its mission centers on creating innovative imaging compounds that facilitate the early identification of pathological changes, thereby supporting earlier diagnosis and improved management of various conditions. Avid's notable product, Amyvid, is an imaging tool utilized in positron emission tomography to detect beta-amyloid plaques in the brain, which plays a crucial role in the assessment of Alzheimer's disease. Through its advancements in molecular imaging, Avid aims to contribute to the development of new therapies and improve clinical outcomes for patients suffering from significant chronic illnesses.

Remon Medical Technologies is a development-stage company based in Caesarea, Israel, specializing in communication technology for medical device applications. It focuses on creating innovative miniature implants and medical devices to improve patient monitoring. The company's flagship products include RemonCHF, which is designed to monitor the hemodynamic status of patients suffering from congestive heart failure, and RemonAAA, a device that tracks pressure levels following endograft procedures in patients with abdominal aortic aneurysms. Through its advanced monitoring solutions, Remon Medical Technologies aims to enhance patient care and outcomes in critical healthcare scenarios.

Remon Medical Technologies is a development-stage company based in Caesarea, Israel, specializing in communication technology for medical device applications. It focuses on creating innovative miniature implants and medical devices to improve patient monitoring. The company's flagship products include RemonCHF, which is designed to monitor the hemodynamic status of patients suffering from congestive heart failure, and RemonAAA, a device that tracks pressure levels following endograft procedures in patients with abdominal aortic aneurysms. Through its advanced monitoring solutions, Remon Medical Technologies aims to enhance patient care and outcomes in critical healthcare scenarios.

EyeTel Imaging, founded in 1996, specializes in developing advanced imaging technologies aimed at preventing vision loss associated with undetected diabetic retinopathy. The company's flagship product, the EyeTel Retinal Imaging System, utilizes the DigiScope, a semi-automated fundus camera that captures high-quality images, facilitating the detection of various ocular conditions, including age-related macular degeneration and glaucoma. EyeTel also operates the EyeTel Reading Center, a telemedicine service that offers expert analysis of patient images by trained specialists, ensuring accurate diagnoses. Collaborating with the Wilmer Eye Institute and manufacturing partner Topzone in China, EyeTel has successfully enhanced its retinal imaging capabilities while maintaining a commitment to cost-effectiveness and ease of use. The technology is clinically validated and designed for primary care settings, reflecting the company's dedication to improving patient care in a convenient manner.

Perlegen Sciences engages in the discovery and commercialization of genetic variations that provide physicians with information to improve the clinical decision-making process and patient treatment outcomes. Its products include MammaPLUS, a breast cancer risk stratifier and a panel of common genetic variants that stratifies individual genetic and background/clinical risk for those at moderately elevated risk for non-familial breast cancer, as well as impacts the risk for developing invasive breast cancer; and Genotype Browser Website that provides a way to access and view the results of a study of genetic variation in various diverse human populations. Perlegen Sciences, Inc. was founded in 2000 and is based in Mountain View, California.

NexCura is a provider of online decision support services aimed at enhancing communication between patients and physicians. The company's applications and custom services are offered through an application service provider model, enabling the collection of comprehensive clinical data. NexCura's tools include the NexProfiler, which integrates clinical evidence with personal concerns and individual patient circumstances to assist in pre-treatment decision-making. Additionally, the company offers patient education and market research services, delivering valuable insights to healthcare organizations, pharmaceutical companies, physicians, and patients alike.

Pacific Biotech develops and markets diagnostic tests for detection of pregnancy, infectious diseases, strep throat, and mononucleosis.